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$399+ Cheap flights from Tuscany to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/7. Fares are subject to change and may not be available on all flights or dates of travel.
FLR — SFO
Nov 8 — Nov 151
Sat 11/8
Sat 11/15
1 adult, Economy
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Find flight deals from Tuscany to San Francisco

Cheapest flights from Tuscany to San Francisco
Explore the most affordable flight options available from Tuscany to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 9, 2025.

This Booking.com deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/207:15 pmFLR - SFO
1 stop29h 50mTAP AIR PORTUGAL
Fri 11/287:10 pmSFO - FLR
1 stop31h 25mTAP AIR PORTUGAL
Deal found 10/9$449
This Cheapflightsfares deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/229:20 amFCO - SFO
Nonstop13h 05mITA Airways
Thu 10/304:05 pmSFO - FCO
Nonstop12h 10mITA Airways
Deal found 10/8$565
This Expedia deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/223:40 pmFCO - SFO
Nonstop12h 35mLufthansa
Fri 10/3110:40 pmSFO - FCO
1 stop16h 20mLufthansa
Deal found 10/7$566
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1110:20 amFCO - SFO
1 stop20h 27mUnited Airlines
Sat 10/1811:40 amSFO - FCO
1 stop36h 35mUnited Airlines
Deal found 10/6$571
This Expedia deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2311:00 amFCO - SFO
1 stop20h 55mBritish Airways
Sun 11/305:30 pmSFO - FCO
1 stop19h 25mBritish Airways
Deal found 10/8$585
This Mytrip deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/218:50 pmFCO - SFO
2 stops26h 55mMultiple Airlines
Sat 11/294:35 pmSFO - FCO
1 stop17h 10mMultiple Airlines
Deal found 10/9$588
This lol.travel deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/309:10 amFCO - SFO
Nonstop12h 55mITA Airways
Thu 11/133:05 pmSFO - FCO
Nonstop12h 10mITA Airways
Deal found 10/9$592
This lol.travel deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/57:10 pmFLR - SFO
1 stop26h 55mITA Airways
Wed 11/129:05 amSFO - FLR
2 stops20h 40mITA Airways
Deal found 10/8$594
This lol.travel deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/179:20 amFCO - SFO
Nonstop13h 05mITA Airways
Wed 10/223:15 pmSFO - FCO
Nonstop12h 00mITA Airways
Deal found 10/8$594
This KLM deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/56:10 amFCO - SFO
1 stop14h 40mMultiple Airlines
Sun 11/163:40 pmSFO - FCO
1 stop14h 35mMultiple Airlines
Deal found 10/8$595
This lol.travel deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2011:00 amFCO - SFO
1 stop22h 35mBritish Airways
Thu 12/48:40 pmSFO - FCO
1 stop17h 10mBritish Airways
Deal found 10/8$596
This KLM deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/56:10 amFCO - SFO
1 stop14h 40mKLM
Sun 11/168:15 amSFO - FCO
1 stop17h 15mKLM
Deal found 10/8$599

Cheap flight deals from Tuscany to San Francisco

Keep the following information in mind while searching for Tuscany to San Francisco flight deals. Data was last updated October 9, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$449
(Booking.com)

One-way from

$399
(Mytrip)

Popular in

December

Cheapest in

January

Average price

$652
Provider with most accurate pricing for Florence Peretola-San Francisco flight deals.
Search Deals
Provider most trusted by Cheapflights users for Florence Peretola-San Francisco flights.
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From Tuscany to San Francisco
Search Deals
One-way flight from Tuscany to San Francisco
Search Deals
High demand for flights, 4% potential price rise
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Tuscany to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 9, 2025.
Use the filters below to find and compare flights from Tuscany to San Francisco that are best for you.

Fly from

Tuscany

Fly to

San Francisco

Route

Depart

Return

Price

RomeSan Francisco

FCO - SFO

FCOSFO

Rome Fiumicino

Wed 1/14

6:10 am-11:50 am

1 stop14h 40m

San Francisco

Wed 1/28

3:40 pm-10:45 pm

1 stop22h 05m

$593

RomeSan Francisco

FCO - SFO

FCOSFO

Rome Fiumicino

Tue 2/17

6:10 am-11:50 am

1 stop14h 40m

San Francisco

Mon 2/23

11:05 am-3:15 pm

2 stops19h 10m

$593

FlorenceSan Francisco

FLR - SFO

FLRSFO

Florence Peretola

Wed 11/5

7:10 pm-1:05 pm

1 stop26h 55m

San Francisco

Wed 11/12

9:05 am-2:45 pm

2 stops20h 40m

$594

RomeSan Francisco

FCO - SFO

FCOSFO

Rome Fiumicino

Wed 1/14

10:40 am-12:47 am

2 stops23h 07m

San Francisco

Wed 1/28

12:30 pm-4:55 pm

2 stops19h 25m

$594

RomeSan Francisco

FCO - SFO

FCOSFO

Rome Fiumicino

Fri 11/7

6:10 am-11:50 am

1 stop14h 40m

San Francisco

Mon 11/17

12:25 pm-5:25 pm

2 stops20h 00m

$595

RomeSan Francisco

FCO - SFO

FCOSFO

Rome Fiumicino

Tue 2/17

6:10 am-11:50 am

1 stop14h 40m

San Francisco

Sun 2/22

10:10 am-11:45 am

2 stops16h 35m

$595

RomeSan Francisco

FCO - SFO

FCOSFO

Rome Fiumicino

Tue 2/17

6:10 am-11:50 am

1 stop14h 40m

San Francisco

Tue 2/24

10:31 am-3:15 pm

2 stops19h 44m

$595

RomeSan Francisco

FCO - SFO

FCOSFO

Rome Fiumicino

Sun 11/23

1:10 pm-10:05 pm

1 stop17h 55m

San Francisco

Sun 11/30

5:30 pm-5:50 pm

1 stop15h 20m

$600

RomeSan Francisco

FCO - SFO

FCOSFO

Rome Fiumicino

Fri 10/24

1:35 pm-9:21 am

1 stop28h 46m

San Francisco

Thu 10/30

12:15 pm-4:55 pm

2 stops20h 40m

$600

RomeSan Francisco

CIA - SFO

CIASFO

Rome Ciampino

Fri 11/21

9:20 pm-9:22 pm

3 stops33h 02m

San Francisco

Sat 11/29

8:25 am-9:30 pm

3 stops28h 05m

$624

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/8

Showing 1-10 of 59 results
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Best time to book a flight from Tuscany to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Tuscany with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Tuscany to San Francisco

What is the cheapest month to book a flight from Tuscany to San Francisco?

Currently, April is the cheapest month in which you can book a flight from Tuscany to San Francisco (average of $533). Flying from Tuscany to San Francisco in December is currently the most expensive (average of $734). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TO to SFO?

Find hourly flight availability from Tuscany to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 9, 2025.

It’s optimal to fly from Tuscany to San Francisco in the evening. By choosing this option you can save up to 37% on the cost of your flight, compared to a flight in the afternoon.

Related info for your journey

Find useful and relevant information for your journey from Tuscany to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from Tuscany?

    For a flight from Tuscany to San Francisco, you will be flying into San Francisco. San Francisco (SFO) is just 11.8 mi from the center of the city.

  • How long is the flight from Tuscany to San Francisco?

    Departing from Tuscany to San Francisco will take you 14h 40m. There are 6246 mi between Tuscany and San Francisco. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Tuscany to San Francisco one-way?

    $404 is the cheapest one-way deal found within the past few days, from TAP AIR PORTUGAL. You may also be able to find cheap deals on Finnair and British Airways, with prices starting from $416 and $745, respectively.

  • What are the most popular routes from Tuscany to San Francisco?

    When deciding which route to take from Tuscany to San Francisco consider Rome Fiumicino - San Francisco, Rome Ciampino - San Francisco or Florence Peretola - San Francisco as they are the most popular.

  • Can I find deals for flights from Tuscany to San Francisco that include hotel bookings?

    Yes. In addition to deals on Tuscany to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Tuscany to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Tuscany to San Francisco.

  • Can I find deals for business class flights from Tuscany to San Francisco?

    Yes. Cheapflights offers flight deals from Tuscany to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Tuscany to San Francisco?

    Currently, April is the cheapest month in which you can book a flight from Tuscany to San Francisco (average of $533). Flying from Tuscany to San Francisco in December is currently the most expensive (average of $734). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
Santa Cruz
Livermore
South San Francisco
Turlock
Antioch
Watsonville
Santa Clara
Manteca
Sunnyvale
Vacaville
Hollister
Foster City
Union City
Vallejo
Fairfield
Burlingame
Redwood City
Lodi
San Mateo

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Tuscany to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Tuscany to San Francisco

Discover the top 2 airlines that operate flights from Tuscany to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 9, 2025.
AirlineCheapestAverageFlexibilityOn-time
LufthansaCheapest$554Average$790FlexibilityNo cancel feeOn-time76%
United AirlinesCheapest$566Average$714FlexibilityNo cancel feeOn-time69%

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