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$191+ Cheap flights from Mexico City (TLC) to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/16. Fares are subject to change and may not be available on all flights or dates of travel.
TLC — SFO
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Mexico City to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Mexico City (TLC) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$385
(Kiwi.com)

One-way from

$191
(Trip.com)

Popular in

October

Cheapest in

February

Average price

$386
From Mexico City Toluca Intl to San Francisco
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One-way flight from Mexico City Toluca Intl to San Francisco
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Highest demand for flights based on searches. 25% potential increase in price ($137 potential increase over avg. RT price).
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Cheapest flight prices on average. 11% potential price decrease ($41 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Mexico City to San Francisco

Cheapest flights from Mexico City to San Francisco
Explore the most affordable flight options available from Mexico City to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/143:25 pmTLC - SFO
2 stops30h 57mMultiple Airlines
Tue 10/211:27 pmSFO - TLC
1 stop26h 38mMultiple Airlines
Deal found 9/16$385
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/77:40 pmTLC - SFO
2 stops26h 30mMultiple Airlines
Mon 11/1011:47 amSFO - TLC
1 stop24h 28mMultiple Airlines
Deal found 9/16$422
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/3011:15 amTLC - SFO
1 stop10h 24mMultiple Airlines
Thu 11/65:45 amSFO - TLC
2 stops35h 32mMultiple Airlines
Deal found 9/15$472

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico City to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Mexico City to San Francisco that are best for you.

Fly from

Mexico City

Fly to

San Francisco

Route

Depart

Return

Price

Mexico CitySan Francisco

TLC - SFO

TLCSFO

Mexico City Toluca Intl

Tue 10/14

3:25 pm-9:22 pm

2 stops30h 57m

San Francisco

Tue 10/21

1:27 pm-5:05 pm

1 stop26h 38m

$385

Mexico CitySan Francisco

TLC - SFO

TLCSFO

Mexico City Toluca Intl

Fri 11/7

7:40 pm-8:10 pm

2 stops26h 30m

San Francisco

Mon 11/10

11:47 am-2:15 pm

1 stop24h 28m

$422

Mexico CitySan Francisco

TLC - SFO

TLCSFO

Mexico City Toluca Intl

Thu 10/30

11:15 am-8:39 pm

1 stop10h 24m

San Francisco

Thu 11/6

5:45 am-7:17 pm

2 stops35h 32m

$472

Mexico CitySan Francisco

TLC - SFO

TLCSFO

Mexico City Toluca Intl

Tue 12/16

9:00 am-9:08 pm

2 stops14h 08m

$191

Mexico CitySan Francisco

TLC - SFO

TLCSFO

Mexico City Toluca Intl

Wed 12/17

6:00 am-9:08 pm

2 stops17h 08m

$191

Mexico CitySan Francisco

TLC - SFO

TLCSFO

Mexico City Toluca Intl

Wed 10/8

11:15 am-6:19 pm

1 stop8h 04m

$220

Mexico CitySan Francisco

TLC - SFO

TLCSFO

Mexico City Toluca Intl

Tue 10/7

11:15 am-6:19 pm

1 stop8h 04m

$220

Mexico CitySan Francisco

TLC - SFO

TLCSFO

Mexico City Toluca Intl

Thu 10/9

11:15 am-6:07 pm

1 stop7h 52m

$221

Mexico CitySan Francisco

TLC - SFO

TLCSFO

Mexico City Toluca Intl

Wed 11/19

10:45 am-8:39 pm

1 stop11h 54m

$226

Mexico CitySan Francisco

TLC - SFO

TLCSFO

Mexico City Toluca Intl

Wed 10/22

11:15 am-6:19 pm

1 stop8h 04m

$227

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 11 results
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Best time to book a flight from Mexico City to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Mexico City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City to San Francisco

What is the cheapest month to book a flight from Mexico City to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Mexico City to San Francisco (average of $276). Flying from Mexico City to San Francisco in June is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Mexico City to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find deals for flights from Mexico City to San Francisco that include hotel bookings?

    Yes. In addition to deals on Mexico City to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to San Francisco.

  • Can I find deals for business class flights from Mexico City to San Francisco?

    Yes. Cheapflights offers flight deals from Mexico City to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Mexico City to San Francisco (average of $276). Flying from Mexico City to San Francisco in June is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
Santa Cruz
Livermore
South San Francisco
Turlock
Antioch
Watsonville
Santa Clara
Manteca
Sunnyvale
Hollister
Vacaville
Foster City
Union City
Vallejo
Burlingame
Redwood City
San Mateo
San Leandro
Lathrop

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