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$342+ Cheap flights from Prague (PRG) to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/30. Fares are subject to change and may not be available on all flights or dates of travel.
PRG — SFO
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheapflights Tip: The best prices from Václav Havel Prague to San Francisco are usually found in September or August, booked 60 days in advance, depart on a Monday or Tuesday and return on a Wednesday

Cheap flight deals from Prague to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Prague (PRG) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$501
(Finnair)

One-way from

$342
(Trip.com)

Popular in

December

Cheapest in

September

Average price

$655
From Václav Havel Prague to San Francisco
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One-way flight from Václav Havel Prague to San Francisco
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Highest demand for flights based on searches. 8% potential increase in price ($70 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Prague to San Francisco

Cheapest flights from Prague to San Francisco
Explore the most affordable flight options available from Prague to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Finnair deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/57:35 pmPRG - SFO
2 stops32h 26mMultiple Airlines
Mon 12/155:30 pmSFO - PRG
1 stop18h 05mMultiple Airlines
Deal found 9/10$502
This lol.travel deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/307:15 pmPRG - SFO
1 stop29h 50mTAP AIR PORTUGAL
Fri 11/147:10 pmSFO - PRG
1 stop38h 15mTAP AIR PORTUGAL
Deal found 9/10$503
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/291:45 pmPRG - SFO
1 stop34h 15mAmerican Airlines
Sat 11/155:00 pmSFO - PRG
2 stops20h 50mAmerican Airlines
Deal found 9/11$505
This lol.travel deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/411:40 amPRG - SFO
2 stops21h 19mFinnair
Tue 11/1112:49 pmSFO - PRG
2 stops21h 01mFinnair
Deal found 9/11$506
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/237:10 amPRG - SFO
1 stop19h 15mAmerican Airlines
Sun 11/92:06 pmSFO - PRG
2 stops19h 04mAmerican Airlines
Deal found 9/10$507
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/148:10 amPRG - SFO
2 stops20h 11mAmerican Airlines
Sat 10/254:45 pmSFO - PRG
2 stops19h 05mAmerican Airlines
Deal found 9/11$508
This oojo deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/147:30 pmPRG - SFO
1 stop28h 05mTAP AIR PORTUGAL
Sat 10/257:35 pmSFO - PRG
1 stop31h 45mTAP AIR PORTUGAL
Deal found 9/11$509
This Billigflug deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Billigflug is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/36:45 amPRG - SFO
2 stops20h 41mMultiple Airlines
Sun 11/162:06 pmSFO - PRG
2 stops19h 04mMultiple Airlines
Deal found 9/11$510
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/316:00 amPRG - SFO
2 stops22h 43mAmerican Airlines
Sun 11/163:54 pmSFO - PRG
2 stops17h 16mAmerican Airlines
Deal found 9/11$511
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/216:40 amPRG - SFO
2 stops20h 59mAmerican Airlines
Mon 11/101:11 pmSFO - PRG
2 stops19h 19mAmerican Airlines
Deal found 9/10$512
This Finnair deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/307:35 pmPRG - SFO
2 stops33h 08mFinnair
Wed 11/1210:16 amSFO - PRG
2 stops23h 34mFinnair
Deal found 9/11$513
This Finnair deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/147:35 pmPRG - SFO
2 stops34h 21mFinnair
Tue 11/1810:16 amSFO - PRG
2 stops23h 34mFinnair
Deal found 9/10$516

Cheapflights Fare Finder

 
Customize your flight search to find flights from Prague to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Prague to San Francisco that are best for you.

Fly from

Prague

Fly to

San Francisco

Route

Depart

Return

Price

PragueSan Francisco

PRG - SFO

PRGSFO

Václav Havel Prague

Fri 12/5

7:35 pm-7:01 pm

2 stops32h 26m

San Francisco

Mon 12/15

5:30 pm-8:35 pm

1 stop18h 05m

$502

PragueSan Francisco

PRG - SFO

PRGSFO

Václav Havel Prague

Fri 12/5

7:35 pm-7:01 pm

2 stops32h 26m

San Francisco

Mon 12/15

12:37 pm-6:50 pm

2 stops21h 13m

$512

PragueSan Francisco

PRG - SFO

PRGSFO

Václav Havel Prague

Thu 10/30

7:35 pm-8:43 pm

2 stops33h 08m

San Francisco

Fri 11/14

12:49 pm-6:50 pm

2 stops21h 01m

$512

PragueSan Francisco

PRG - SFO

PRGSFO

Václav Havel Prague

Fri 11/14

7:35 pm-8:56 pm

2 stops34h 21m

San Francisco

Tue 11/18

10:16 am-6:50 pm

2 stops23h 34m

$513

PragueSan Francisco

PRG - SFO

PRGSFO

Václav Havel Prague

Sat 2/7

6:00 am-11:50 am

1 stop14h 50m

San Francisco

Tue 2/10

6:05 am-11:40 am

2 stops20h 35m

$531

PragueSan Francisco

PRG - SFO

PRGSFO

Václav Havel Prague

Tue 11/4

6:00 am-11:50 am

1 stop14h 50m

San Francisco

Tue 11/11

7:00 am-11:40 am

2 stops19h 40m

$531

PragueSan Francisco

PRG - SFO

PRGSFO

Václav Havel Prague

Thu 10/30

6:00 am-12:50 pm

1 stop14h 50m

San Francisco

Fri 11/14

6:00 am-11:55 am

2 stops20h 55m

$534

PragueSan Francisco

PRG - SFO

PRGSFO

Václav Havel Prague

Sat 2/7

6:00 am-11:50 am

1 stop14h 50m

San Francisco

Wed 2/11

7:00 am-11:40 am

2 stops19h 40m

$534

PragueSan Francisco

PRG - SFO

PRGSFO

Václav Havel Prague

Wed 10/29

9:30 pm-6:43 pm

2 stops29h 13m

San Francisco

Fri 11/14

3:30 pm-9:05 pm

2 stops20h 35m

$536

PragueSan Francisco

PRG - SFO

PRGSFO

Václav Havel Prague

Thu 10/30

8:10 am-8:44 am

2 stops32h 34m

$342

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 17 results
1
2

Best time to book a flight from Prague to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Prague with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Prague to San Francisco

How far ahead should I book a flight from Prague to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Prague to San Francisco. Price data was last updated on August 29, 2025.

The price you pay for your flight from Prague to San Francisco may vary depending on when you book. For the best chance of a lower fare, look to book 60 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Prague to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Prague to San Francisco (average of $276). Flying from Prague to San Francisco in June is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PRG to SFO?

Find hourly flight availability from Prague to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

When flying from Prague to San Francisco, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 35% versus a flight in the afternoon.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated September 11, 2025.
See what other customers who have flown with United Airlines, American Airlines, and Lufthansa from Prague to San Francisco have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,937 reviews

Boarding

7.7

Crew

8.1

Entertainment

7.1

Overall

7.4

Comfort

7.3

Food

6.6

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
United Airlines
7.4
Good
8,937 reviews
United Airlines
7.4
Good
8,937 reviews

Boarding

7.7

Crew

8.1

Entertainment

7.1

Overall

7.4

Comfort

7.3

Food

6.6

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,937 reviews

Boarding

7.7

Crew

8.1

Entertainment

7.1

Overall

7.4

Comfort

7.3

Food

6.6

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
Lufthansa
6.8
Okay
7,409 reviews
United Airlines
7.4
Good
8,937 reviews

Boarding

7.7

Crew

8.1

Entertainment

7.1

Overall

7.4

Comfort

7.3

Food

6.6

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
British Airways
6.7
Okay
7,361 reviews
United Airlines
7.4
Good
8,937 reviews

Boarding

7.7

Crew

8.1

Entertainment

7.1

Overall

7.4

Comfort

7.3

Food

6.6

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
Condor
6.3
Okay
364 reviews
United Airlines
7.4
Good
8,937 reviews

Boarding

7.7

Crew

8.1

Entertainment

7.1

Overall

7.4

Comfort

7.3

Food

6.6

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.

Related info for your journey

Find useful and relevant information for your journey from Prague to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Prague to San Francisco?

    Departing from Prague to San Francisco will take you 32h 26m. Prague and San Francisco are separated by a distance of 5822 mi.

  • What are the cheapest airlines flying from Prague to San Francisco round-trip?

    Cheapflights users have booked flights from Prague to San Francisco round-trip from $405. Other airlines that can offer you cheap pricing are Condor, from $490, and British Airways, from $529. American Airlines is 45% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Prague to San Francisco that include hotel bookings?

    Yes. In addition to deals on Prague to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Prague to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Prague to San Francisco.

  • Can I find deals for business class flights from Prague to San Francisco?

    Yes. Cheapflights offers flight deals from Prague to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Prague to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Prague to San Francisco (average of $276). Flying from Prague to San Francisco in June is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
Santa Cruz
Livermore
South San Francisco
Turlock
Antioch
Watsonville
Manteca
Santa Clara
Sunnyvale
Hollister
Vacaville
Foster City
Vallejo
Burlingame
Redwood City
Union City
San Leandro
San Mateo
Lathrop

Browse thousands of different options on Cheapflights for your next trip

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Top 6 airlines flying from Prague to San Francisco

Discover the top 6 airlines that operate flights from Prague to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$405Average$593FlexibilityNo cancel feeOn-time71%
CondorCheapest$490Average$620FlexibilityNo cancel feeOn-time76%
British AirwaysCheapest$529Average$738FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$604Average$715FlexibilityNo cancel feeOn-time69%
SWISSCheapest$621Average$870FlexibilityNo cancel feeOn-time79%
LufthansaCheapest$670Average$979FlexibilityNo cancel feeOn-time76%

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