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$552+ Cheap flights from Palermo (PMO) to San Francisco (SFO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/12. Fares are subject to change and may not be available on all flights or dates of travel.
PMO — SFO
Jan 14 — Jan 211
Wed 1/14
Wed 1/21
1 adult, Economy
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Cheap flight deals from Palermo to San Francisco

Best flights from Palermo to San Francisco
Discover carefully curated flight deals from Palermo to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 15, 2025.

This lol.travel deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/126:10 amPMO - SFO
1 stop15h 55mMultiple Airlines
Sun 3/1510:35 amSFO - PMO
2 stops19h 55mMultiple Airlines
Deal found 12/13$552
This lol.travel deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/199:30 amPMO - SFO
1 stop34h 35mTurkish Airlines
Fri 1/236:50 pmSFO - PMO
1 stop37h 55mTurkish Airlines
Deal found 12/14$707
This KLM deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/276:10 amPMO - SFO
2 stops25h 54mKLM
Tue 2/37:00 amSFO - PMO
2 stops22h 30mKLM
Deal found 12/13$707
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/286:10 amPMO - SFO
2 stops24h 27mLufthansa
Wed 2/49:25 pmSFO - PMO
1 stop28h 55mLufthansa
Deal found 12/14$840
This United Airlines deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/186:10 amPMO - SFO
2 stops24h 12mUnited Airlines
Sun 2/227:00 amSFO - PMO
2 stops19h 40mUnited Airlines
Deal found 12/12$948
This lol.travel deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/286:10 amPMO - SFO
2 stops24h 15mMultiple Airlines
Wed 2/47:30 amSFO - PMO
2 stops22h 00mMultiple Airlines
Deal found 12/14$563
This FlightHub deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/1712:10 pmPMO - SFO
1 stop16h 25mMultiple Airlines
Sun 1/258:25 amSFO - PMO
2 stops20h 15mMultiple Airlines
Deal found 12/13$796
This Expedia deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/277:10 pmPMO - SFO
2 stops35h 25mMultiple Airlines
Tue 2/37:25 pmSFO - PMO
1 stop33h 30mMultiple Airlines
Deal found 12/13$855
This lol.travel deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/197:10 pmPMO - SFO
2 stops30h 35mMultiple Airlines
Fri 1/236:50 pmSFO - PMO
1 stop37h 55mMultiple Airlines
Deal found 12/14$879

Find flight deals from Palermo to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Palermo (PMO) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 15, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$552
(lol.travel)
Provider with most accurate pricing for Palermo Punta Raisi-San Francisco flight deals.
Search Deals
Provider most trusted by Cheapflights users for Palermo Punta Raisi-San Francisco flights.
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From Palermo Punta Raisi to San Francisco
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Palermo to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Palermo to San Francisco that are best for you.

Fly from

Palermo

Fly to

San Francisco

Route

Depart

Return

Price

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Thu 3/12

6:10 am-2:05 pm

1 stop15h 55m

San Francisco

Sun 3/15

10:35 am-2:30 pm

2 stops19h 55m

$552

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Wed 1/28

6:10 am-9:25 pm

2 stops24h 15m

San Francisco

Wed 2/4

7:30 am-2:30 pm

2 stops22h 00m

$563

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Mon 1/19

9:30 am-11:05 am

1 stop34h 35m

San Francisco

Fri 1/23

6:50 pm-5:45 pm

1 stop37h 55m

$707

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Tue 1/27

6:10 am-11:04 pm

2 stops25h 54m

San Francisco

Tue 2/3

7:00 am-2:30 pm

2 stops22h 30m

$707

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Sat 1/17

12:10 pm-7:35 pm

1 stop16h 25m

San Francisco

Sun 1/25

8:25 am-1:40 pm

2 stops20h 15m

$796

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Wed 1/28

6:10 am-9:37 pm

2 stops24h 27m

San Francisco

Wed 2/4

9:25 pm-11:20 am

1 stop28h 55m

$840

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Tue 1/27

7:10 pm-9:35 pm

2 stops35h 25m

San Francisco

Tue 2/3

7:25 pm-1:55 pm

1 stop33h 30m

$855

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Mon 1/19

7:10 pm-4:45 pm

2 stops30h 35m

San Francisco

Fri 1/23

6:50 pm-5:45 pm

1 stop37h 55m

$879

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Wed 2/18

6:10 am-9:22 pm

2 stops24h 12m

San Francisco

Sun 2/22

7:00 am-11:40 am

2 stops19h 40m

$948

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/13

Compare providers for flights from Palermo to San Francisco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Palermo to San Francisco in December.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Palermo-San Francisco flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Palermo-San Francisco flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Palermo-San Francisco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Palermo-San Francisco flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Palermo-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Palermo to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Palermo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Palermo to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Palermo to San Francisco?

    Turkish Airlines and KLM can get you from Palermo to San Francisco in just under 25h 54m. Your travel time can differ by up to 8h 41m. The distance from Palermo to San Francisco is about 6478 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Palermo to San Francisco one-way?

    The cheapest airlines for a one-way flight from Palermo to San Francisco are ITA Airways ($553), SWISS ($636), and Lufthansa ($664).

  • Can I find deals for flights from Palermo to San Francisco that include hotel bookings?

    Yes. In addition to deals on Palermo to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Palermo to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Palermo to San Francisco.

  • Can I find deals for business class flights from Palermo to San Francisco?

    Yes. Cheapflights offers flight deals from Palermo to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
South San Francisco
Santa Cruz
Livermore
Turlock
Manteca
Watsonville
Redwood City
Sunnyvale
Santa Clara
San Bruno
Daly City
San Carlos
Vallejo
Hollister
San Ramon
Foster City
Union City
Davis
Emeryville

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