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$432+ Cheap flights from Palermo (PMO) to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/17. Fares are subject to change and may not be available on all flights or dates of travel.
PMO — SFO
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Palermo to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Palermo (PMO) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$635
(American Airlines)

One-way from

$432
(Mytrip)
From Palermo Punta Raisi to San Francisco
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One-way flight from Palermo Punta Raisi to San Francisco
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Find flight deals from Palermo to San Francisco

Cheapest flights from Palermo to San Francisco
Explore the most affordable flight options available from Palermo to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This lol.travel deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/158:30 pmPMO - SFO
1 stop25h 55mITA Airways
Tue 9/233:15 pmSFO - PMO
1 stop18h 05mITA Airways
Deal found 9/10$564
This SWISS deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SWISS is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/267:10 pmPMO - SFO
1 stop30h 20mSWISS
Sun 11/27:25 pmSFO - PMO
1 stop34h 05mSWISS
Deal found 9/11$711
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/159:45 amPMO - SFO
2 stops24h 14mUnited Airlines
Tue 9/2311:59 pmSFO - PMO
2 stops22h 16mUnited Airlines
Deal found 9/11$736
This Lufthansa deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/266:25 pmPMO - SFO
1 stop34h 10mLufthansa
Sun 11/22:40 pmSFO - PMO
2 stops17h 15mLufthansa
Deal found 9/11$753
This Mytrip deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/267:10 amPMO - SFO
2 stops21h 25mMultiple Airlines
Sun 11/27:25 pmSFO - PMO
2 stops18h 55mMultiple Airlines
Deal found 9/11$886
This Air Canada deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/155:50 amPMO - SFO
2 stops22h 48mMultiple Airlines
Tue 9/2311:45 pmSFO - PMO
2 stops25h 55mMultiple Airlines
Deal found 9/10$999
This Iberia deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/154:25 pmPMO - SFO
1 stop34h 45mIberia
Tue 9/238:10 pmSFO - PMO
1 stop32h 35mIberia
Deal found 9/11$1,132

Cheapflights Fare Finder

 
Customize your flight search to find flights from Palermo to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Palermo to San Francisco that are best for you.

Fly from

Palermo

Fly to

San Francisco

Route

Depart

Return

Price

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Thu 3/5

1:55 pm-6:45 pm

1 stop37h 50m

San Francisco

Mon 3/9

11:59 pm-10:45 am

2 stops50h 46m

$635

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Thu 3/5

6:10 am-1:05 pm

1 stop15h 55m

San Francisco

Mon 3/9

4:05 pm-6:20 pm

1 stop18h 15m

$675

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Sun 10/26

7:10 pm-5:30 pm

1 stop30h 20m

San Francisco

Sun 11/2

7:25 pm-2:30 pm

1 stop34h 05m

$711

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Sun 10/26

6:25 pm-8:35 pm

1 stop34h 10m

San Francisco

Sun 11/2

2:40 pm-4:55 pm

2 stops17h 15m

$753

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Sun 10/26

7:10 am-8:35 pm

2 stops21h 25m

San Francisco

Sun 11/2

7:25 pm-11:20 pm

2 stops18h 55m

$886

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Mon 11/10

7:15 pm-4:30 pm

1 stop30h 15m

San Francisco

Fri 11/21

8:25 am-1:55 pm

2 stops44h 30m

$3,770

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Tue 11/11

3:15 pm-4:30 pm

2 stops34h 15m

San Francisco

Sat 11/22

8:25 am-5:25 pm

2 stops24h 00m

$3,785

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Wed 9/17

6:00 am-9:30 am

3 stops36h 30m

$432

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Sat 9/27

8:15 am-9:24 pm

2 stops22h 09m

$559

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Fri 10/10

9:20 am-10:35 am

1 stop34h 15m

$621

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 13 results
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Best time to book a flight from Palermo to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Palermo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Palermo to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Palermo to San Francisco?

    American Airlines and ITA Airways can get you from Palermo to San Francisco in just under 15h 55m. Your travel time can differ by up to 21h 55m. The distance from Palermo to San Francisco is about 6478 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Palermo to San Francisco that include hotel bookings?

    Yes. In addition to deals on Palermo to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Palermo to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Palermo to San Francisco.

  • Can I find deals for business class flights from Palermo to San Francisco?

    Yes. Cheapflights offers flight deals from Palermo to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Palermo to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Palermo to San Francisco (average of $276). Flying from Palermo to San Francisco in June is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
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Santa Clara
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Hollister
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