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$221+ Cheap flights from Mexico City Federal District to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/18. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — SFO
Dec 16 — Dec 231
Tue 12/16
Tue 12/23
1 adult, Economy
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Cheap flight deals from Mexico City Federal District to San Francisco

Keep the following information in mind while searching for Mexico City Federal District to San Francisco flight deals. Data was last updated November 16, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$344
(Delta)

One-way from

$221
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$391

Good round-trip deal

$274 or less

Good one-way deal

$254 or less
Provider with most accurate pricing for Mexico City Benito Juarez-San Francisco flight deals.
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Provider most trusted by Cheapflights users for Mexico City Benito Juarez-San Francisco flights.
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From Mexico City Federal District to San Francisco
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One-way flight from Mexico City Federal District to San Francisco
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Highest demand for flights based on searches. 7% potential increase in price ($30 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Price to beat on a round-trip flight from Mexico City Federal District to San Francisco.
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Price to beat on a one-way flight from Mexico City Federal District to San Francisco.
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Find flight deals from Mexico City Federal District to San Francisco

Cheapest flights from Mexico City Federal District to San Francisco
Explore the most affordable flight options available from Mexico City Federal District to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 16, 2025.

This United Airlines deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/109:05 amMEX - SFO
1 stop8h 11mUnited Airlines
Thu 1/81:15 pmSFO - MEX
Nonstop4h 20mUnited Airlines
Deal found 11/15$345
This United Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/23:20 pmMEX - SFO
1 stop10h 39mUnited Airlines
Mon 1/1210:47 amSFO - MEX
Nonstop4h 23mUnited Airlines
Deal found 11/13$346
This deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/247:50 amMEX - SFO
1 stop12h 08mUnited Airlines
Wed 12/3110:47 amSFO - MEX
Nonstop4h 23mUnited Airlines
Deal found 11/14$351
This Frontier deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/48:10 amMEX - SFO
2 stops13h 53mFrontier
Fri 12/511:38 pmSFO - MEX
2 stops20h 22mFrontier
Deal found 11/13$352
This United Airlines deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/231:50 pmMEX - SFO
Nonstop4h 59mUnited Airlines
Tue 12/210:49 pmSFO - MEX
Nonstop4h 16mUnited Airlines
Deal found 11/15$360
This United Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/261:50 pmMEX - SFO
Nonstop4h 59mUnited Airlines
Tue 12/27:10 pmSFO - MEX
1 stop12h 55mUnited Airlines
Deal found 11/16$361
This United Airlines deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/51:50 pmMEX - SFO
Nonstop4h 59mUnited Airlines
Sun 12/710:49 pmSFO - MEX
Nonstop4h 16mUnited Airlines
Deal found 11/14$362
This American Airlines deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/512:30 pmMEX - SFO
1 stop12h 55mAmerican Airlines
Mon 12/83:54 pmSFO - MEX
1 stop6h 16mAmerican Airlines
Deal found 11/15$364
This United Airlines deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:10 amMEX - SFO
Nonstop4h 59mUnited Airlines
Mon 12/812:43 amSFO - MEX
1 stop7h 22mUnited Airlines
Deal found 11/15$365
This United Airlines deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:10 amMEX - SFO
Nonstop4h 59mUnited Airlines
Mon 12/87:10 pmSFO - MEX
1 stop12h 55mUnited Airlines
Deal found 11/15$366
This American Airlines deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/234:13 pmMEX - SFO
1 stop9h 20mAmerican Airlines
Tue 12/23:00 pmSFO - MEX
1 stop7h 10mAmerican Airlines
Deal found 11/15$370
This Kiwi.com deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/26:00 amTLC - SFO
2 stops13h 24mMultiple Airlines
Sat 12/67:00 amSFO - TLC
1 stop8h 05mMultiple Airlines
Deal found 11/14$479

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico City Federal District to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 16, 2025.
Use the filters below to find and compare flights from Mexico City Federal District to San Francisco that are best for you.

Fly from

Mexico City Federal District

Fly to

San Francisco

Route

Depart

Return

Price

Mexico CitySan Francisco

MEX - SFO

MEXSFO

Mexico City Benito Juarez

Fri 2/13

8:45 am-11:51 am

Nonstop5h 06m

San Francisco

Tue 2/17

6:00 am-7:35 pm

1 stop11h 35m

$344

Mexico CitySan Francisco

MEX - SFO

MEXSFO

Mexico City Benito Juarez

Tue 1/20

8:45 am-11:51 am

Nonstop5h 06m

San Francisco

Sun 1/25

12:40 am-1:40 pm

1 stop11h 00m

$344

Mexico CitySan Francisco

MEX - SFO

MEXSFO

Mexico City Benito Juarez

Fri 1/16

8:45 am-11:51 am

Nonstop5h 06m

San Francisco

Sun 1/25

12:40 am-1:40 pm

1 stop11h 00m

$344

Mexico CitySan Francisco

MEX - SFO

MEXSFO

Mexico City Benito Juarez

Tue 12/2

12:25 pm-11:59 pm

1 stop13h 34m

San Francisco

Wed 1/7

10:49 pm-5:05 am

Nonstop4h 16m

$346

Mexico CitySan Francisco

MEX - SFO

MEXSFO

Mexico City Benito Juarez

Tue 12/2

10:05 am-11:59 pm

1 stop15h 54m

San Francisco

Sat 1/10

1:15 pm-7:35 pm

Nonstop4h 20m

$346

Mexico CitySan Francisco

MEX - SFO

MEXSFO

Mexico City Benito Juarez

Wed 1/14

8:45 am-11:51 am

Nonstop5h 06m

San Francisco

Thu 1/22

11:02 am-7:35 pm

1 stop6h 33m

$346

Mexico CitySan Francisco

MEX - SFO

MEXSFO

Mexico City Benito Juarez

Wed 11/26

6:10 am-9:09 am

Nonstop4h 59m

San Francisco

Tue 12/2

10:49 pm-5:05 am

Nonstop4h 16m

$360

Mexico CitySan Francisco

MEX - SFO

MEXSFO

Mexico City Benito Juarez

Wed 12/3

6:10 am-9:09 am

Nonstop4h 59m

San Francisco

Sun 12/7

10:49 pm-5:05 am

Nonstop4h 16m

$361

Mexico CitySan Francisco

MEX - SFO

MEXSFO

Mexico City Benito Juarez

Thu 12/4

6:10 pm-9:04 pm

Nonstop4h 54m

San Francisco

Sun 12/7

10:49 pm-5:05 am

Nonstop4h 16m

$361

Mexico CitySan Francisco

MEX - SFO

MEXSFO

Mexico City Benito Juarez

Wed 12/3

6:10 am-9:09 am

Nonstop4h 59m

San Francisco

Mon 12/8

12:43 am-10:05 am

1 stop7h 22m

$366

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/15

Showing 1-10 of 38 results
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Best time to book a flight from Mexico City Federal District to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Mexico City Federal District with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City Federal District to San Francisco

What is the cheapest month to book a flight from Mexico City Federal District to San Francisco?

Currently, February is the cheapest month in which you can book a flight from Mexico City Federal District to San Francisco (average of $117). Flying from Mexico City Federal District to San Francisco in August is currently the most expensive (average of $188). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DF to SFO?

Find hourly flight availability from Mexico City Federal District to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 16, 2025.

One of the essential ways to save on airfare from Mexico City Federal District to San Francisco is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 29% on airfare.

What is the cheapest day to fly from Mexico City Federal District to San Francisco?

Use this chart to determine the cheapest time to fly round-trip from Mexico City Federal District to San Francisco. Price data was last updated on November 2, 2025.

Travelers seeking maximum savings on their Mexico City Federal District to San Francisco flight should consider departing on Tuesday evenings when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Mexico City Federal District to San Francisco

Explore weekly flight availability from Mexico City Federal District to San Francisco. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated November 16, 2025.

The most flights from MXDF to SFO are scheduled on a Monday (14 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (13 on average).

Related info for your journey

Find useful and relevant information for your journey from Mexico City Federal District to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from Mexico City Federal District?

    San Francisco (SFO), located 11.8 mi from the city center, is the airport you fly into when you book flights from Mexico City Federal District to San Francisco.

  • How popular is this Mexico City Federal District to San Francisco flight route?

    The Mexico City Federal District to San Francisco flight path was viewed by 39 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Mexico City Federal District to San Francisco?

    Delta and United Airlines can get you from Mexico City Federal District to San Francisco in just under 5h 06m. Your travel time can differ by up to 8h 28m. The distance between Mexico City Federal District and San Francisco is about 1881 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most reliable airlines from Mexico City Federal District to San Francisco?

    Consider WestJet (100%), Delta (97%) or Aeromexico (97%) when booking your flight. These represent the most reliable airlines when flying from Mexico City Federal District to San Francisco.

  • What are the cheapest flights from Mexico City Federal District to San Francisco?

    On average you can expect to pay $613 for a flight from Mexico City Federal District to San Francisco. The cheapest flight overall is $222 while the most popular route, (Mexico City Benito Juarez - San Francisco) is currently priced at $319.

  • Can I find deals for flights from Mexico City Federal District to San Francisco that include hotel bookings?

    Yes. In addition to deals on Mexico City Federal District to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City Federal District to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City Federal District to San Francisco.

  • Can I find deals for business class flights from Mexico City Federal District to San Francisco?

    Yes. Cheapflights offers flight deals from Mexico City Federal District to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City Federal District to San Francisco?

    Currently, February is the cheapest month in which you can book a flight from Mexico City Federal District to San Francisco (average of $117). Flying from Mexico City Federal District to San Francisco in August is currently the most expensive (average of $188). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
South San Francisco
Santa Cruz
Livermore
Turlock
Manteca
Watsonville
Sunnyvale
Santa Clara
Vallejo
Hollister
San Bruno
Foster City
Redwood City
Union City
Burlingame
Lodi
San Mateo
Vacaville
Lathrop

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Alternative routes for Mexico City Federal District to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.
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Mérida to Los Angeles flights
Cancún to Ontario flights
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Top 3 airlines flying from Mexico City Federal District to San Francisco

Discover the top 3 airlines that operate flights from Mexico City Federal District to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
AeromexicoCheapest$232Average$415FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$255Average$359FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$255Average$357FlexibilityNo cancel feeOn-time69%

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