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$268+ Cheap flights from Jose Maria Cordova Intl (MDE) to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/16. Fares are subject to change and may not be available on all flights or dates of travel.
MDE — SFO
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheapflights Tip: The best prices from Medellín Jose Maria Cordova Intl to San Francisco are usually found in May or June, booked 9 days in advance, depart on a Thursday or Tuesday and return on a Monday

Cheap flight deals from Jose Maria Cordova Intl to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Jose Maria Cordova Intl (MDE) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$463
(JetBlue)

One-way from

$268
(Kiwi.com)

Popular in

December

Cheapest in

May

Average price

$553
From Medellín Jose Maria Cordova Intl to San Francisco
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One-way flight from Medellín Jose Maria Cordova Intl to San Francisco
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Highest demand for flights based on searches. 11% potential increase in price ($71 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Jose Maria Cordova Intl to San Francisco

Cheapest flights from Jose Maria Cordova Intl to San Francisco
Explore the most affordable flight options available from Jose Maria Cordova Intl to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This JetBlue deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/11:30 pmMDE - SFO
1 stop11h 40mJetBlue
Wed 10/1511:20 pmSFO - MDE
1 stop12h 45mJetBlue
Deal found 9/10$463
This Viajes Éxito deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Viajes Éxito is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/21:30 pmMDE - SFO
1 stop11h 40mJetBlue
Thu 10/2310:35 amSFO - MDE
1 stop25h 30mJetBlue
Deal found 9/9$487
This Expedia deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/261:10 pmMDE - SFO
1 stop22h 15mJetBlue
Sun 11/29:44 pmSFO - MDE
1 stop13h 48mJetBlue
Deal found 9/10$504
This deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/281:10 pmMDE - SFO
1 stop12h 21mJetBlue
Mon 11/39:44 pmSFO - MDE
1 stop13h 48mJetBlue
Deal found 9/9$510
This JetBlue deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/71:30 pmMDE - SFO
1 stop11h 46mJetBlue
Tue 10/1411:20 pmSFO - MDE
1 stop12h 45mJetBlue
Deal found 9/9$518
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/117:00 amMDE - SFO
1 stop18h 59mAmerican Airlines
Tue 11/1811:59 pmSFO - MDE
1 stop11h 10mAmerican Airlines
Deal found 9/11$521
This lastminute.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/241:30 pmMDE - SFO
1 stop23h 57mJetBlue
Sun 11/28:00 amSFO - MDE
1 stop27h 32mJetBlue
Deal found 9/8$525
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/261:35 pmMDE - SFO
2 stops21h 10mAmerican Airlines
Sun 11/26:15 pmSFO - MDE
2 stops16h 54mAmerican Airlines
Deal found 9/10$526
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/76:00 amMDE - SFO
2 stops15h 21mAmerican Airlines
Tue 10/146:00 amSFO - MDE
2 stops12h 15mAmerican Airlines
Deal found 9/9$532
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/186:00 amMDE - SFO
1 stop18h 54mAmerican Airlines
Fri 9/2611:10 amSFO - MDE
1 stop23h 40mAmerican Airlines
Deal found 9/11$538

Cheapflights Fare Finder

 
Customize your flight search to find flights from Jose Maria Cordova Intl to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Medellín Jose Maria Cordova Intl Airport to San Francisco that are best for you.

Fly from

Jose Maria Cordova Intl

Fly to

San Francisco

Route

Depart

Return

Price

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Tue 10/7

1:30 pm-11:16 pm

1 stop11h 46m

San Francisco

Tue 10/14

11:20 pm-2:05 pm

1 stop12h 45m

$518

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Tue 11/11

6:59 pm-1:00 pm

2 stops45h 01m

San Francisco

Tue 11/18

11:10 pm-12:55 pm

1 stop10h 45m

$521

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Fri 10/24

1:30 pm-11:27 am

1 stop23h 57m

San Francisco

Sun 11/2

8:00 am-2:32 pm

1 stop27h 32m

$525

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Thu 10/23

1:16 am-9:29 am

2 stops34h 13m

San Francisco

Sun 11/2

11:10 pm-12:55 pm

1 stop10h 45m

$526

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Tue 11/11

7:00 am-10:59 pm

1 stop18h 59m

San Francisco

Tue 11/18

11:59 pm-2:09 pm

1 stop11h 10m

$528

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Mon 2/2

6:50 am-11:08 pm

1 stop19h 18m

San Francisco

Tue 2/3

12:27 am-8:52 pm

2 stops17h 25m

$532

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Wed 10/29

6:00 am-10:59 pm

1 stop18h 59m

San Francisco

Wed 11/19

4:21 pm-2:09 pm

2 stops18h 48m

$532

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Tue 10/7

6:00 am-7:23 pm

2 stops15h 23m

San Francisco

Tue 10/14

11:59 pm-8:15 pm

1 stop18h 16m

$532

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Sun 10/26

9:17 am-11:39 pm

1 stop16h 22m

San Francisco

Sat 11/1

1:36 am-4:59 pm

1 stop13h 23m

$541

MedellínSan Francisco

MDE - SFO

MDESFO

Medellín Jose Maria Cordova Intl

Sun 11/9

1:30 am-3:00 pm

2 stops16h 30m

San Francisco

Tue 11/18

6:00 am-11:39 pm

2 stops14h 39m

$542

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 22 results
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Best time to book a flight from Jose Maria Cordova Intl to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Jose Maria Cordova Intl with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medellín Jose Maria Cordova Intl Airport to San Francisco

How far ahead should I book a flight from Medellín Jose Maria Cordova Intl Airport to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Jose Maria Cordova Intl to San Francisco. Price data was last updated on August 29, 2025.

To ensure you get the cheapest price possible for a flight from Medellín Jose Maria Cordova Intl Airport to San Francisco, you should look to book at least 9 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Medellín Jose Maria Cordova Intl Airport to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Medellín Jose Maria Cordova Intl Airport to San Francisco (average of $276). Flying from Medellín Jose Maria Cordova Intl Airport to San Francisco in June is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDE to SFO?

Find hourly flight availability from Jose Maria Cordova Intl to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

A simple way to save on the total cost of your ticket is to fly from Medellín Jose Maria Cordova Intl Airport to San Francisco at noon. If you’re flexible enough to do this you can expect to save up to 14% on your trip compared to booking a flight in the evening.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated September 11, 2025.
Peruse reviews from past customers who have flown with Copa Airlines, United Airlines, and American Airlines from Medellín Jose Maria Cordova Intl Airport to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,531 reviews

Entertainment

6.8

Crew

8.1

Boarding

7.8

Comfort

7.4

Overall

7.6

Food

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
Copa Airlines
7.6
Good
1,531 reviews
Copa Airlines
7.6
Good
1,531 reviews

Entertainment

6.8

Crew

8.1

Boarding

7.8

Comfort

7.4

Overall

7.6

Food

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
United Airlines
7.4
Good
8,937 reviews
Copa Airlines
7.6
Good
1,531 reviews

Entertainment

6.8

Crew

8.1

Boarding

7.8

Comfort

7.4

Overall

7.6

Food

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
American Airlines
7.2
Good
10,000 reviews
Copa Airlines
7.6
Good
1,531 reviews

Entertainment

6.8

Crew

8.1

Boarding

7.8

Comfort

7.4

Overall

7.6

Food

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
Avianca
6.7
Okay
2,436 reviews
Copa Airlines
7.6
Good
1,531 reviews

Entertainment

6.8

Crew

8.1

Boarding

7.8

Comfort

7.4

Overall

7.6

Food

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring

Related info for your journey

Find useful and relevant information for your journey from Jose Maria Cordova Intl to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from Medellín Jose Maria Cordova Intl?

    Located just 11.8 mi from the city center, San Francisco is the airport most travelers will use when flying to San Francisco from Medellín Jose Maria Cordova Intl. Booking flights from Medellín Jose Maria Cordova Intl to San Francisco (SFO) should be relatively easy as there are 0 daily inbound flights from Medellín Jose Maria Cordova Intl from 4 different airlines.

  • How long is the flight from Medellín Jose Maria Cordova Intl Airport to San Francisco?

    Airlines like JetBlue and American Airlines fly from Medellín Jose Maria Cordova Intl Airport to San Francisco in about 11h 46m. The time it takes to get you to your destination can typically vary by up to 7h 13m. Medellín Jose Maria Cordova Intl Airport and San Francisco are separated by a distance of 3653 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Medellín Jose Maria Cordova Intl Airport to San Francisco round-trip?

    Cheapflights users have booked flights from Medellín Jose Maria Cordova Intl Airport to San Francisco round-trip from $314. Other airlines that can offer you cheap pricing are Avianca, from $386, and United Airlines, from $440. Copa Airlines is 45% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Jose Maria Cordova Intl to San Francisco that include hotel bookings?

    Yes. In addition to deals on Jose Maria Cordova Intl to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Jose Maria Cordova Intl to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jose Maria Cordova Intl to San Francisco.

  • Can I find deals for business class flights from Jose Maria Cordova Intl to San Francisco?

    Yes. Cheapflights offers flight deals from Jose Maria Cordova Intl to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medellín Jose Maria Cordova Intl Airport to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Medellín Jose Maria Cordova Intl Airport to San Francisco (average of $276). Flying from Medellín Jose Maria Cordova Intl Airport to San Francisco in June is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Jose Maria Cordova Intl to San Francisco

Discover the top 4 airlines that operate flights from Jose Maria Cordova Intl to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$314Average$591FlexibilityNo cancel feeOn-time70%
AviancaCheapest$386Average$571FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$440Average$621FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$587Average$724FlexibilityNo cancel feeOn-time71%

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