$189+ Cheap flights from Harrisburg to San Francisco (MDT - SFO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/13. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — SFO
Nov 10 — Nov 171
Round-trip
1 adult, Economy
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Find cheap flights from Harrisburg to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Harrisburg to San Francisco
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Best
Last-minute
One-way
Cheapest flights from Harrisburg to San FranciscoExplore the most affordable flight options available from Harrisburg to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 11, 2026.
Explore the most affordable flight options available from Harrisburg to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 11, 2026.
This Delta deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/226:22 pm -
1 stop8h 36m
Fri 12/41:36 pm -
1 stop6h 34m
Deal found 10/8![Delta logo]()
$399
This American Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2312:18 pm -
1 stop10h 33m
Sun 11/110:58 pm -
1 stop7h 13m
Deal found 10/10![American Airlines logo]()
$439
This Delta deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:05 pm -
1 stop8h 57m
Wed 12/212:17 pm -
1 stop7h 53m
Deal found 10/8![Delta logo]()
$449
This Delta deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/302:56 pm -
1 stop9h 43m
Sun 11/110:45 pm -
1 stop9h 48m
Deal found 10/8![Delta logo]()
$459
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:15 pm -
1 stop8h 45m
Mon 11/309:50 pm -
1 stop8h 33m
Deal found 10/7![American Airlines logo]()
$469
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/176:00 am -
1 stop8h 34m
Mon 1/411:30 pm -
1 stop7h 29m
Deal found 10/8![United Airlines logo]()
$471
This Delta deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:00 am -
1 stop9h 34m
Mon 10/261:30 pm -
1 stop6h 28m
Deal found 10/7![Delta logo]()
$479
This Delta deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/226:22 pm -
1 stop8h 36m
Thu 12/36:00 am -
2 stops14h 10m
Deal found 10/7![Delta logo]()
$483
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:15 am -
1 stop8h 30m
Sun 11/229:50 pm -
1 stop8h 33m
Deal found 10/8![American Airlines logo]()
$489
This Delta deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:05 pm -
1 stop8h 57m
Wed 12/21:36 pm -
1 stop6h 34m
Deal found 10/8![Delta logo]()
$499
This Delta deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:00 am -
1 stop7h 48m
Wed 12/21:36 pm -
1 stop6h 34m
Deal found 10/8![Delta logo]()
$519
Best flights from Harrisburg to San FranciscoDiscover carefully curated flight deals from Harrisburg to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 11, 2026.
Discover carefully curated flight deals from Harrisburg to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 11, 2026.
This Delta deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/226:22 pm -
1 stop8h 36m
Fri 12/41:36 pm -
1 stop6h 34m
Deal found 10/7![Delta logo]()
$399
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1810:30 am -
1 stop10h 05m
Wed 11/251:50 pm -
1 stop6h 54m
Deal found 10/6![United Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:00 pm -
2 stops10h 39m
Wed 11/2511:00 pm -
1 stop9h 23m
Deal found 10/6![American Airlines logo]()
$582
This United Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/96:20 am -
1 stop8h 50m
Wed 1/136:01 am -
1 stop9h 43m
Deal found 10/10![United Airlines logo]()
$529
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/226:15 am -
1 stop8h 07m
Fri 11/277:00 am -
1 stop8h 57m
Deal found 10/8![United Airlines logo]()
$529
This Delta deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2212:09 pm -
2 stops13h 20m
Wed 12/26:00 am -
1 stop7h 16m
Deal found 10/7![Delta logo]()
$593
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/268:15 am -
1 stop8h 15m
Tue 12/15:00 am -
2 stops12h 54m
Deal found 10/8![United Airlines logo]()
$613
Last-minute flights from Harrisburg to San FranciscoDiscover last-minute flight deals from Harrisburg to San Francisco. Data last updated October 11, 2026 and is based on user searches.
Discover last-minute flight deals from Harrisburg to San Francisco. Data last updated October 11, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:00 am -
1 stop9h 34m
Mon 10/261:30 pm -
1 stop6h 28m
Deal found 10/7![Delta logo]()
$479
This American Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2312:18 pm -
1 stop10h 33m
Sun 11/110:58 pm -
1 stop7h 13m
Deal found 10/10![American Airlines logo]()
$439
This Delta deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/302:56 pm -
1 stop9h 43m
Sun 11/110:45 pm -
1 stop9h 48m
Deal found 10/8![Delta logo]()
$459
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:15 am -
1 stop8h 30m
Sun 11/229:50 pm -
1 stop8h 33m
Deal found 10/8![American Airlines logo]()
$489
This Delta deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:00 am -
1 stop7h 48m
Wed 12/21:36 pm -
1 stop6h 34m
Deal found 10/8![Delta logo]()
$519
This Delta deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:05 pm -
1 stop8h 57m
Wed 12/212:17 pm -
1 stop7h 53m
Deal found 10/8![Delta logo]()
$449
This Delta deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/226:22 pm -
1 stop8h 36m
Fri 12/41:36 pm -
1 stop6h 34m
Deal found 10/8![Delta logo]()
$399
This Delta deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/226:22 pm -
1 stop8h 36m
Thu 12/36:00 am -
2 stops14h 10m
Deal found 10/7![Delta logo]()
$483
This Delta deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:05 pm -
1 stop8h 57m
Wed 12/21:36 pm -
1 stop6h 34m
Deal found 10/8![Delta logo]()
$499
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:15 am -
1 stop8h 07m
Sat 12/56:35 am -
1 stop7h 21m
Deal found 10/8![United Airlines logo]()
$529
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:15 pm -
1 stop8h 45m
Mon 11/309:50 pm -
1 stop8h 33m
Deal found 10/7![American Airlines logo]()
$469
One-way flights from Harrisburg to San FranciscoSearch for one-way flight options from Harrisburg to San Francisco. Find affordable one-way fares based on user searches. Data last updated October 11, 2026.
Search for one-way flight options from Harrisburg to San Francisco. Find affordable one-way fares based on user searches. Data last updated October 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/134:05 pm -
3 stops48h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/10![Multiple Airlines logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/171:21 pm -
3 stops44h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![Multiple Airlines logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/309:18 pm -
3 stops47h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![Multiple Airlines logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/209:14 pm -
2 stops52h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/9![Multiple Airlines logo]()
$259
This Kiwi.com deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/228:40 pm -
2 stops22h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![Multiple Airlines logo]()
$276
This Kiwi.com deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/59:59 pm -
2 stops28h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![Multiple Airlines logo]()
$294
This Kiwi.com deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/207:35 pm -
2 stops41h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![Multiple Airlines logo]()
$308
Find flight deals from Harrisburg to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $399 (United Airlines) |
One-way from | $189 (Kiwi.com) |
Popular in | July |
Cheapest in | April |
Average price | $459 |
Cheapflights Fare Finder
Customize your flight search to find flights from Harrisburg to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 11, 2026.
Use the filters below to find and compare flights from Harrisburg to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
HarrisburgSan Francisco
MDT Harrisburg - SFO San Francisco
MDTSFO
Harrisburg
Sun 12/13
4:05 pm-1:53 pm
3 stops48h 48m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$189
HarrisburgSan Francisco
MDT Harrisburg - SFO San Francisco
MDTSFO
Harrisburg
Sun 11/22
8:40 pm-4:38 pm
2 stops22h 58m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$276
HarrisburgSan Francisco
MDT Harrisburg - SFO San Francisco
MDTSFO
Harrisburg
Thu 11/5
9:59 pm-11:04 pm
2 stops28h 05m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$294
HarrisburgSan Francisco
MDT Harrisburg - SFO San Francisco
MDTSFO
Harrisburg
Fri 11/20
7:35 pm-9:44 am
2 stops41h 09m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$308
HarrisburgSan Francisco
MDT Harrisburg - SFO San Francisco
MDTSFO
Harrisburg
Sun 12/13
12:20 pm-11:43 pm
2 stops14h 23m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$382
Quickest round-trip
HarrisburgSan Francisco
MDT Harrisburg - SFO San Francisco
MDTSFO
Harrisburg
Sun 11/22
2:38 pm-8:35 pm
1 stop8h 57m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$389
HarrisburgSan Francisco
MDT Harrisburg - SFO San Francisco
MDTSFO
Harrisburg
Sun 12/13
6:00 am-12:27 pm
1 stop9h 27m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$389
HarrisburgSan Francisco
MDT Harrisburg - SFO San Francisco
MDTSFO
Harrisburg
Sun 11/22
6:22 pm-11:58 pm
1 stop8h 36m
San Francisco
Fri 12/4
1:36 pm-11:10 pm
1 stop6h 34m
$399
HarrisburgSan Francisco
MDT Harrisburg - SFO San Francisco
MDTSFO
Harrisburg
Wed 11/18
10:30 am-5:35 pm
1 stop10h 05m
San Francisco
Wed 11/25
1:50 pm-11:44 pm
1 stop6h 54m
$399
HarrisburgSan Francisco
MDT Harrisburg - SFO San Francisco
MDTSFO
Harrisburg
Tue 12/29
9:15 am-7:50 pm
3 stops37h 35m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$427
Showing 1-10 of 15 resultsSorted by cheapest first
Compare providers for flights from Harrisburg to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to San Francisco in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Harrisburg-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Harrisburg-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Harrisburg-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Harrisburg-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Harrisburg to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Harrisburg with our price prediction graph.
MDT-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Harrisburg to San Francisco
Prices
More
How far ahead should I book a flight from Harrisburg to San Francisco?
The best time to book flights from Harrisburg to San Francisco is 24 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Harrisburg to San Francisco?
Currently, April is the cheapest month in which you can book a flight from Harrisburg to San Francisco (average of $416). Flying from Harrisburg to San Francisco in July is currently the most expensive (average of $756). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Harrisburg to San Francisco?
Airfare is typical for this route at the moment.
Harrisburg to San Francisco flights typically cost between $398 and $488 in November.The cheapest round-trip price found within the last 5 days was $399 on United Airlines (Nov 18-Nov 25).
What’s the top layover airport for flights from Harrisburg to San Francisco?
Share of 1-stop round-trip flights from Harrisburg to San Francisco chosen by Cheapflights users in the past 12 months, using the same layover each way.
Chicago (ORD) – chosen by Cheapflights users on 88% of 1-stop itineraries from Harrisburg to San Francisco on Cheapflights.
What’s the cheapest layover airport for flights from Harrisburg to San Francisco?
Average round-trip fare for 1-stop flights from Harrisburg to San Francisco, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Charlotte (CLT) is the most affordable 1-stop option, with an average round-trip price of $378.
What’s the fastest layover option from Harrisburg to San Francisco?
Shortest average travel time for 1-stop one-way flights from Harrisburg to San Francisco, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Chicago (ORD) have the shortest average one-way travel time for 1-stop routes: 7h 48m.
Which airport typically offers the quickest layover for flights from Harrisburg to San Francisco?
Average layover duration for 1-stop one-way flights from Harrisburg to San Francisco, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Chicago (ORD) offer the fastest connection on this route, with an average layover time of 0h 58m.
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated October 11, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Harrisburg to San Francisco by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Overall
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Crew
8.5
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Overall
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Crew
8.5
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Overall
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Crew
8.5
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Overall
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
TUS - LAX
Related info for your journey
Find useful and relevant information for your journey from Harrisburg to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Clara
Santa Cruz
Walnut Creek
San Bruno
Emeryville
Hayward
Burlingame
Rancho Cordova
Roseville
Redwood City
Cupertino
Newark
Fairfield
San Ramon
Manteca
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Alternative routes for Harrisburg to San Francisco
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Harrisburg and San Francisco flights
Browse other Harrisburg and San Francisco flight options. Last updated on October 11, 2026.
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Check out other popular destinations found by fellow travelers in 2026
Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 11, 2026.
Top 3 airlines flying from Harrisburg to San Francisco
Discover the top 3 airlines that operate flights from Harrisburg to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$329 | Average$484 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$348 | Average$478 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$353 | Average$491 | FlexibilityNo cancel fee | On-timeN/A |