San Francisco

$190+ Cheap flights from Harrisburg to San Francisco (MDT - SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/23. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — SFO
Apr 13 — Apr 201
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1. Tell us where you want to go

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Cheap flight deals from Harrisburg to San Francisco

Cheapest flights from Harrisburg to San Francisco
Explore the most affordable flight options available from Harrisburg to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 14, 2026.

This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/73:37 pm
MDT
-
SFO
1 stop8h 27m
American Airlines
Tue 4/1410:06 am
SFO
-
MDT
1 stop10h 19m
American Airlines
Deal found 3/10$349
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/235:06 pm
MDT
-
SFO
1 stop9h 04m
American Airlines
Tue 3/3111:49 pm
SFO
-
MDT
1 stop8h 43m
American Airlines
Deal found 3/9$353
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/243:15 pm
MDT
-
SFO
2 stops10h 59m
American Airlines
Mon 3/3012:25 am
SFO
-
MDT
1 stop8h 36m
American Airlines
Deal found 3/9$358
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:53 pm
MDT
-
SFO
1 stop9h 46m
United Airlines
Sun 5/310:35 pm
SFO
-
MDT
1 stop8h 09m
United Airlines
Deal found 3/10$369
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/143:15 pm
MDT
-
SFO
1 stop10h 34m
American Airlines
Tue 3/1711:49 pm
SFO
-
MDT
1 stop8h 43m
American Airlines
Deal found 3/9$377
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/203:37 pm
MDT
-
SFO
1 stop10h 38m
American Airlines
Sun 5/2411:14 pm
SFO
-
MDT
1 stop8h 53m
American Airlines
Deal found 3/12$389
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/43:15 pm
MDT
-
SFO
2 stops11h 29m
American Airlines
Sat 4/1112:06 pm
SFO
-
MDT
1 stop8h 19m
American Airlines
Deal found 3/12$394
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1811:57 am
MDT
-
SFO
1 stop10h 15m
American Airlines
Tue 3/2411:49 pm
SFO
-
MDT
1 stop8h 43m
American Airlines
Deal found 3/13$397
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/225:50 pm
MDT
-
SFO
1 stop10h 52m
United Airlines
Sat 8/811:30 pm
SFO
-
MDT
1 stop7h 39m
United Airlines
Deal found 3/9$401
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/172:56 pm
MDT
-
SFO
1 stop10h 43m
Delta
Tue 9/2211:45 pm
SFO
-
MDT
1 stop8h 51m
Delta
Deal found 3/10$404
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/246:30 am
MDT
-
SFO
1 stop8h 14m
United Airlines
Sat 8/811:30 pm
SFO
-
MDT
1 stop7h 39m
United Airlines
Deal found 3/9$414

Find flight deals from Harrisburg to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 14, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$349
(American Airlines)

One-way from

$190
(Kiwi.com)

Popular in

June

Cheapest in

August

Average price

$458
Provider with most accurate pricing for Harrisburg-San Francisco flight deals.
Provider most trusted by Cheapflights users for Harrisburg-San Francisco flights.
From Harrisburg to San Francisco
One-way flight from Harrisburg to San Francisco
Highest demand for flights based on searches. 9% potential increase in price ($49 potential increase over avg. RT price).
Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
Average for round-trip flights in March 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 14, 2026.
Use the filters below to find and compare flights from Harrisburg to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Sat 8/29

6:30 am-11:25 am

1 stop7h 55m

San Francisco

Sat 9/5

9:30 pm-9:36 am

1 stop9h 06m

$369

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Wed 4/8

6:15 am-12:03 pm

1 stop8h 48m

San Francisco

Mon 4/13

10:38 pm-9:44 am

1 stop8h 06m

$369

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Thu 5/21

5:50 pm-1:42 am

1 stop10h 52m

San Francisco

Wed 5/27

5:05 am-4:54 pm

1 stop8h 49m

$469
Quickest round-trip

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Fri 8/28

6:15 am-11:20 am

1 stop8h 05m

San Francisco

Tue 9/1

1:10 pm-11:25 pm

1 stop7h 15m

$469

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Mon 6/29

7:59 pm-1:15 am

1 stop8h 16m

San Francisco

Fri 7/3

5:05 am-4:54 pm

1 stop8h 49m

$478

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Sat 8/29

6:00 am-3:13 pm

2 stops12h 13m

San Francisco

Wed 9/9

8:00 am-11:28 pm

2 stops12h 28m

$516

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Fri 8/28

11:46 am-7:40 pm

2 stops10h 54m

San Francisco

Tue 9/1

8:00 am-11:51 pm

2 stops12h 51m

$536

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Fri 5/22

5:50 pm-1:42 am

1 stop10h 52m

San Francisco

Wed 5/27

9:00 pm-4:54 pm

2 stops16h 54m

$537

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Wed 6/24

7:59 pm-1:15 am

1 stop8h 16m

San Francisco

Wed 7/1

5:05 am-4:54 pm

1 stop8h 49m

$550

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Thu 5/7

11:53 am-11:01 pm

2 stops14h 08m

San Francisco

Tue 6/16

7:55 am-11:59 pm

2 stops13h 04m

$556

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/12

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

Compare providers for flights from Harrisburg to San Francisco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to San Francisco in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Harrisburg-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Harrisburg-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Harrisburg-San Francisco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Harrisburg-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Harrisburg to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to San Francisco

How far ahead should I book a flight from Harrisburg to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Harrisburg to San Francisco. Price data was last updated on March 6, 2026.

The best time to book flights from Harrisburg to San Francisco is 29 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Harrisburg to San Francisco?

Currently, June is the cheapest month in which you can book a flight from Harrisburg to San Francisco (average of $163). Flying from Harrisburg to San Francisco in September is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated March 14, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Harrisburg to San Francisco by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Overall

7.9

Comfort

7.9

Food

7.2

Crew

8.5

Entertainment

7.8

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Overall

7.9

Comfort

7.9

Food

7.2

Crew

8.5

Entertainment

7.8

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Overall

7.9

Comfort

7.9

Food

7.2

Crew

8.5

Entertainment

7.8

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Overall

7.9

Comfort

7.9

Food

7.2

Crew

8.5

Entertainment

7.8

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Overall

7.9

Comfort

7.9

Food

7.2

Crew

8.5

Entertainment

7.8

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Harrisburg to San Francisco?

    Airlines like United Airlines fly from Harrisburg to San Francisco in about 7h 55m. The time it takes to get you to your destination can typically vary by up to . Harrisburg and San Francisco are separated by a distance of 2430 mi.

  • What are the cheapest airlines flying from Harrisburg to San Francisco round-trip?

    Cheapflights users have booked flights from Harrisburg to San Francisco round-trip from $308. Other airlines that can offer you cheap pricing are United Airlines, from $308, and Delta, from $308. You may be able to fly from Harrisburg to San Francisco for 34% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Harrisburg to San Francisco one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $188. Delta flights start at $224 while deals on United Airlines start at $244 one-way.

  • Can I find deals for flights from Harrisburg to San Francisco that include hotel bookings?

    Yes. In addition to deals on Harrisburg to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to San Francisco.

  • Can I find deals for business class flights from Harrisburg to San Francisco?

    Yes. Cheapflights offers flight deals from Harrisburg to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to San Francisco?

    Currently, June is the cheapest month in which you can book a flight from Harrisburg to San Francisco (average of $163). Flying from Harrisburg to San Francisco in September is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
South San Francisco
Santa Clara
Santa Cruz
Livermore
Roseville
Watsonville
San Bruno
Sunnyvale
Vacaville
Turlock
San Carlos
San Ramon
Redwood City
Daly City
Rancho Cordova
San Lorenzo
Davis
Hollister
Manteca
Union City

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Harrisburg to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Harrisburg to San Francisco

Discover the top 4 airlines that operate flights from Harrisburg to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 14, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$308Average$488FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$308Average$488FlexibilityNo cancel feeOn-time71%
DeltaCheapest$308Average$459FlexibilityNo cancel feeOn-timeN/A
FrontierCheapest$350Average$448FlexibilityNo cancel feeOn-time62%

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