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$228+ Cheap flights from Harrisburg to San Francisco (MDT - SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/5. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — SFO
Mar 27 — Apr 31
Fri 3/27
Fri 4/3
1 adult, Economy
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Cheap flight deals from Harrisburg to San Francisco

Cheapest flights from Harrisburg to San Francisco
Explore the most affordable flight options available from Harrisburg to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 25, 2026.

This United Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:30 am
MDT
-
SFO
1 stop8h 55m
United Airlines
Wed 5/135:30 am
SFO
-
MDT
1 stop8h 23m
United Airlines
Deal found 2/23$329
This American Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:51 pm
MDT
-
SFO
1 stop8h 25m
American Airlines
Wed 8/55:15 am
SFO
-
MDT
1 stop8h 16m
American Airlines
Deal found 2/24$330
This American Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/143:15 pm
MDT
-
SFO
1 stop10h 34m
American Airlines
Tue 3/176:21 am
SFO
-
MDT
1 stop9h 49m
American Airlines
Deal found 2/24$333
This Delta deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/46:00 am
MDT
-
SFO
1 stop8h 04m
Delta
Wed 3/1112:06 pm
SFO
-
MDT
1 stop8h 35m
Delta
Deal found 2/22$347
This American Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/227:40 pm
MDT
-
SFO
1 stop8h 38m
American Airlines
Wed 5/276:01 am
SFO
-
MDT
1 stop10h 01m
American Airlines
Deal found 2/22$349
This Delta deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/202:56 pm
MDT
-
SFO
1 stop9h 25m
Delta
Tue 8/2511:45 pm
SFO
-
MDT
1 stop8h 51m
Delta
Deal found 2/23$354
This United Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/272:07 pm
MDT
-
SFO
1 stop8h 12m
United Airlines
Sun 3/111:20 pm
SFO
-
MDT
1 stop7h 17m
United Airlines
Deal found 2/21$357
This American Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/275:06 pm
MDT
-
SFO
2 stops10h 42m
American Airlines
Sun 3/16:21 am
SFO
-
MDT
1 stop9h 49m
American Airlines
Deal found 2/24$362
This American Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:33 am
MDT
-
SFO
1 stop8h 13m
American Airlines
Mon 3/911:29 pm
SFO
-
MDT
2 stops9h 03m
American Airlines
Deal found 2/24$368

Find flight deals from Harrisburg to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 25, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$329
(United Airlines)

One-way from

$228
(Delta)

Popular in

June

Cheapest in

August

Average price

$433
Provider with most accurate pricing for Harrisburg-San Francisco flight deals.
Search Deals
Provider most trusted by Cheapflights users for Harrisburg-San Francisco flights.
Search Deals
From Harrisburg to San Francisco
Search Deals
One-way flight from Harrisburg to San Francisco
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($48 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 25, 2026.
Use the filters below to find and compare flights from Harrisburg to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Fri 5/22

8:30 pm-1:42 am

1 stop8h 12m

San Francisco

Wed 5/27

11:30 pm-9:35 am

1 stop7h 05m

$329

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Wed 3/25

6:15 am-2:03 pm

1 stop10h 48m

San Francisco

Wed 4/1

6:33 am-4:51 pm

1 stop7h 18m

$329

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Fri 5/8

6:30 am-12:25 pm

1 stop8h 55m

San Francisco

Wed 5/13

5:30 am-4:53 pm

1 stop8h 23m

$329

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Fri 5/8

6:33 pm-12:46 am

1 stop9h 13m

San Francisco

Mon 5/11

8:30 pm-11:07 am

2 stops11h 37m

$457

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Fri 6/5

7:59 pm-1:15 am

1 stop8h 16m

San Francisco

Wed 6/10

5:05 am-4:54 pm

1 stop8h 49m

$499

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Wed 4/15

6:15 am-6:57 pm

2 stops15h 42m

San Francisco

Sun 4/19

10:38 pm-9:44 am

1 stop8h 06m

$511

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Wed 3/11

6:15 am-2:03 pm

1 stop10h 48m

San Francisco

Sun 3/15

9:30 pm-9:32 am

1 stop9h 02m

$613

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Tue 3/10

6:15 am-12:06 pm

1 stop8h 51m

San Francisco

Sat 3/14

9:30 pm-9:32 am

1 stop9h 02m

$613

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Tue 6/9

2:56 pm-11:46 pm

2 stops11h 50m

San Francisco

Fri 6/12

11:45 pm-11:51 am

1 stop9h 06m

$617

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Fri 6/5

7:59 pm-7:35 am

2 stops14h 36m

San Francisco

Mon 6/8

10:35 pm-9:40 am

1 stop8h 05m

$627

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/25

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

Compare providers for flights from Harrisburg to San Francisco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to San Francisco in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Harrisburg-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Harrisburg-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Harrisburg-San Francisco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Harrisburg-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Harrisburg to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to San Francisco

How far ahead should I book a flight from Harrisburg to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Harrisburg to San Francisco. Price data was last updated on February 20, 2026.

The best time to book flights from Harrisburg to San Francisco is 29 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Harrisburg to San Francisco?

Currently, March is the cheapest month in which you can book a flight from Harrisburg to San Francisco (average of $102). Flying from Harrisburg to San Francisco in September is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated February 25, 2026.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Harrisburg to San Francisco by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,237 reviews

Crew

8.5

Entertainment

7.8

Boarding

8.1

Comfort

7.9

Food

7.2

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
7.9
Good
8,237 reviews
Delta
7.9
Good
8,237 reviews

Crew

8.5

Entertainment

7.8

Boarding

8.1

Comfort

7.9

Food

7.2

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
9,348 reviews
Delta
7.9
Good
8,237 reviews

Crew

8.5

Entertainment

7.8

Boarding

8.1

Comfort

7.9

Food

7.2

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
11,352 reviews
Delta
7.9
Good
8,237 reviews

Crew

8.5

Entertainment

7.8

Boarding

8.1

Comfort

7.9

Food

7.2

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Frontier
5.7
Fair
3,040 reviews
Delta
7.9
Good
8,237 reviews

Crew

8.5

Entertainment

7.8

Boarding

8.1

Comfort

7.9

Food

7.2

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Harrisburg to San Francisco?

    Airlines like United Airlines and Delta fly from Harrisburg to San Francisco in about 8h 12m. The time it takes to get you to your destination can typically vary by up to 5h 44m. Harrisburg and San Francisco are separated by a distance of 2430 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Harrisburg to San Francisco round-trip?

    Cheapflights users have booked flights from Harrisburg to San Francisco round-trip from $308. Other airlines that can offer you cheap pricing are United Airlines, from $308, and Delta, from $308. You may be able to fly from Harrisburg to San Francisco for 35% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Harrisburg to San Francisco one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $194. Delta flights start at $224 while deals on United Airlines start at $244 one-way.

  • Can I find deals for flights from Harrisburg to San Francisco that include hotel bookings?

    Yes. In addition to deals on Harrisburg to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to San Francisco.

  • Can I find deals for business class flights from Harrisburg to San Francisco?

    Yes. Cheapflights offers flight deals from Harrisburg to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to San Francisco?

    Currently, March is the cheapest month in which you can book a flight from Harrisburg to San Francisco (average of $102). Flying from Harrisburg to San Francisco in September is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
South San Francisco
Santa Cruz
Santa Clara
Livermore
Roseville
Watsonville
San Bruno
Daly City
Sunnyvale
Vacaville
Turlock
San Carlos
San Ramon
Redwood City
Rancho Cordova
San Lorenzo
Davis
Hollister
Manteca
Union City

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Harrisburg to San Francisco

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Top 4 airlines flying from Harrisburg to San Francisco

Discover the top 4 airlines that operate flights from Harrisburg to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 25, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$308Average$490FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$308Average$501FlexibilityNo cancel feeOn-time71%
DeltaCheapest$308Average$459FlexibilityNo cancel feeOn-timeN/A
FrontierCheapest$350Average$448FlexibilityNo cancel feeOn-time62%

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