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$176+ Cheap flights from Harrisburg to San Francisco (MDT - SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/1. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — SFO
Nov 21 — Nov 281
Fri 11/21
Fri 11/28
1 adult, Economy
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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

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Cheapflights Tip: The best prices from Harrisburg to San Francisco are usually found in September or August, booked 88 days in advance, depart on a Saturday or Tuesday and return on a Wednesday

Find flight deals from Harrisburg to San Francisco

Cheapest flights from Harrisburg to San Francisco
Explore the most affordable flight options available from Harrisburg to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 22, 2025.

This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:00 amMDT - SFO
1 stop7h 46mDelta
Tue 12/97:15 amSFO - MDT
1 stop8h 17mDelta
Deal found 10/20$309
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/35:40 amMDT - SFO
2 stops10h 53mAmerican Airlines
Tue 12/911:59 pmSFO - MDT
1 stop7h 27mAmerican Airlines
Deal found 10/20$314
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/82:35 pmMDT - SFO
1 stop9h 30mUnited Airlines
Wed 11/1211:44 pmSFO - MDT
1 stop7h 22mUnited Airlines
Deal found 10/21$339
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/811:56 amMDT - SFO
2 stops10h 06mAmerican Airlines
Wed 11/127:15 amSFO - MDT
1 stop7h 29mAmerican Airlines
Deal found 10/21$344
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1011:07 amMDT - SFO
2 stops11h 07mAmerican Airlines
Wed 12/176:00 amSFO - MDT
2 stops10h 07mAmerican Airlines
Deal found 10/20$353
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/56:30 amMDT - SFO
1 stop9h 55mUnited Airlines
Sun 11/911:20 pmSFO - MDT
1 stop7h 15mUnited Airlines
Deal found 10/21$369
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/316:44 amMDT - SFO
1 stop9h 27mAmerican Airlines
Mon 11/311:14 pmSFO - MDT
1 stop8h 10mAmerican Airlines
Deal found 10/20$373
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2511:21 amMDT - SFO
1 stop9h 31mAmerican Airlines
Sat 1/1011:13 pmSFO - MDT
1 stop8h 41mAmerican Airlines
Deal found 10/19$409
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2912:33 pmMDT - SFO
1 stop8h 18mDelta
Tue 11/47:15 amSFO - MDT
1 stop7h 15mDelta
Deal found 10/20$414
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2911:40 amMDT - SFO
1 stop9h 19mAmerican Airlines
Tue 11/49:15 amSFO - MDT
2 stops10h 41mAmerican Airlines
Deal found 10/21$419

Cheap flight deals from Harrisburg to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 22, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$309
(Delta)

One-way from

$176
(Kiwi.com)

Popular in

June

Cheapest in

September

Average price

$459
Provider with most accurate pricing for Harrisburg-San Francisco flight deals.
Search Deals
Provider most trusted by Cheapflights users for Harrisburg-San Francisco flights.
Search Deals
From Harrisburg to San Francisco
Search Deals
One-way flight from Harrisburg to San Francisco
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($73 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 22, 2025.
Use the filters below to find and compare flights from Harrisburg to San Francisco that are best for you.

Fly from

Harrisburg

Fly to

San Francisco

Route

Depart

Return

Price

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Wed 12/10

6:00 am-10:46 am

1 stop7h 46m

San Francisco

Wed 12/17

5:50 am-4:13 pm

1 stop7h 23m

$309

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Wed 12/3

6:00 am-10:46 am

1 stop7h 46m

San Francisco

Tue 12/9

7:15 am-6:32 pm

1 stop8h 17m

$309

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Wed 11/5

6:30 am-1:25 pm

1 stop9h 55m

San Francisco

Sun 11/9

11:20 pm-9:35 am

1 stop7h 15m

$369

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Tue 3/3

10:40 am-5:50 pm

1 stop10h 10m

San Francisco

Sat 3/7

10:50 pm-8:55 am

1 stop7h 05m

$409

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Wed 12/24

6:00 am-11:01 am

1 stop8h 01m

San Francisco

Fri 1/9

11:30 am-11:40 pm

1 stop9h 10m

$438

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Sat 11/22

2:35 pm-9:49 pm

1 stop10h 14m

San Francisco

Wed 11/26

10:35 am-9:04 pm

1 stop7h 29m

$443

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Mon 11/17

5:00 pm-11:11 pm

1 stop9h 11m

San Francisco

Mon 11/24

5:50 am-4:15 pm

1 stop7h 25m

$468

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Thu 11/6

2:35 pm-9:05 pm

1 stop9h 30m

San Francisco

Sun 11/9

6:45 am-6:55 pm

1 stop9h 10m

$469

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Thu 11/6

6:30 am-5:38 pm

2 stops14h 08m

San Francisco

Mon 11/10

11:20 pm-9:35 am

1 stop7h 15m

$474

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Thu 12/25

11:21 am-5:52 pm

1 stop9h 31m

San Francisco

Fri 1/2

10:49 pm-1:17 pm

2 stops11h 28m

$479

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/21

Showing 1-10 of 17 results
1
2

Compare providers for flights from Harrisburg to San Francisco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to San Francisco in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Harrisburg-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Harrisburg-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Harrisburg-San Francisco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Harrisburg-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Harrisburg to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to San Francisco

How far ahead should I book a flight from Harrisburg to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Harrisburg to San Francisco. Price data was last updated on October 17, 2025.

The best time to book flights from Harrisburg to San Francisco is 37 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Harrisburg to San Francisco?

Currently, March is the cheapest month in which you can book a flight from Harrisburg to San Francisco (average of $102). Flying from Harrisburg to San Francisco in September is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDT to SFO?

Find hourly flight availability from Harrisburg to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 22, 2025.

A simple way to save on the total cost of your ticket is to fly from Harrisburg to San Francisco at noon. If you’re flexible enough to do this you can expect to save up to 22% on your trip compared to booking a flight in the morning.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated October 22, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Harrisburg to San Francisco by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,981 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Overall

7.9

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
7.9
Good
7,981 reviews
Delta
7.9
Good
7,981 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Overall

7.9

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,990 reviews
Delta
7.9
Good
7,981 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Overall

7.9

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
11,028 reviews
Delta
7.9
Good
7,981 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Overall

7.9

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Frontier
5.8
Fair
3,129 reviews
Delta
7.9
Good
7,981 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Overall

7.9

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Harrisburg to San Francisco?

    Airlines like Delta and United Airlines fly from Harrisburg to San Francisco in about 7h 46m. The time it takes to get you to your destination can typically vary by up to 2h 09m. Harrisburg and San Francisco are separated by a distance of 2430 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Harrisburg to San Francisco round-trip?

    Cheapflights users have booked flights from Harrisburg to San Francisco round-trip from $308. Other airlines that can offer you cheap pricing are United Airlines, from $308, and Delta, from $308. You may be able to fly from Harrisburg to San Francisco for 34% less than the average price by searching for these airlines.

  • Can I find deals for flights from Harrisburg to San Francisco that include hotel bookings?

    Yes. In addition to deals on Harrisburg to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to San Francisco.

  • Can I find deals for business class flights from Harrisburg to San Francisco?

    Yes. Cheapflights offers flight deals from Harrisburg to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to San Francisco?

    Currently, March is the cheapest month in which you can book a flight from Harrisburg to San Francisco (average of $102). Flying from Harrisburg to San Francisco in September is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
Santa Cruz
Livermore
South San Francisco
Turlock
Antioch
Watsonville
Santa Clara
Manteca
Sunnyvale
Vacaville
Vallejo
Hollister
Foster City
Union City
Fairfield
Burlingame
Redwood City
Lodi
San Mateo

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Top 4 airlines flying from Harrisburg to San Francisco

Discover the top 4 airlines that operate flights from Harrisburg to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$308Average$514FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$308Average$490FlexibilityNo cancel feeOn-time71%
DeltaCheapest$308Average$418FlexibilityNo cancel feeOn-timeN/A
FrontierCheapest$350Average$448FlexibilityNo cancel feeOn-time62%

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