$316+ Cheap flights from Grand Cayman to San Francisco (SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/14. Fares are subject to change and may not be available on all flights or dates of travel.
GCM — SFO
May 3 — May 101
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Grand Cayman to San Francisco
Cheapest
Best
One-way
Cheapest flights from Grand Cayman to San FranciscoExplore the most affordable flight options available from Grand Cayman to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 3, 2026.
Explore the most affordable flight options available from Grand Cayman to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 3, 2026.
This Air Canada deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/1310:55 am
GCM
- SFO
1 stop12h 15m
Air Canada
Wed 6/174:30 pm
SFO
- GCM
1 stop16h 55m
Air Canada
Deal found 4/2![Air Canada logo]()
$735
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/1312:31 pm
GCM
- SFO
2 stops12h 07m
American Airlines
Wed 6/176:54 pm
SFO
- GCM
2 stops14h 36m
American Airlines
Deal found 3/30![American Airlines logo]()
$791
Best flights from Grand Cayman to San FranciscoDiscover carefully curated flight deals from Grand Cayman to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 3, 2026.
Discover carefully curated flight deals from Grand Cayman to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 3, 2026.
This Air Canada deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/1310:55 am
GCM
- SFO
1 stop12h 15m
Air Canada
Wed 6/174:30 pm
SFO
- GCM
1 stop16h 55m
Air Canada
Deal found 4/2![Air Canada logo]()
$735
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/1312:31 pm
GCM
- SFO
2 stops12h 07m
American Airlines
Wed 6/176:54 pm
SFO
- GCM
2 stops14h 36m
American Airlines
Deal found 3/30![American Airlines logo]()
$791
One-way flights from Grand Cayman to San FranciscoSearch for one-way flight options from Grand Cayman to San Francisco. Find affordable one-way fares based on user searches. Data last updated April 3, 2026.
Search for one-way flight options from Grand Cayman to San Francisco. Find affordable one-way fares based on user searches. Data last updated April 3, 2026.
This Southwest deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1412:45 pm
GCM
- SFO
2 stops13h 25m
Southwest
Deal found 3/30![Southwest logo]()
$316
This JetBlue deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/161:25 pm
GCM
- SFO
1 stop12h 26m
JetBlue
Deal found 4/3![JetBlue logo]()
$340
This Southwest deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/221:05 pm
GCM
- SFO
2 stops11h 40m
Southwest
Deal found 4/2![Southwest logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2211:30 am
GCM
- SFO
3 stops32h 21m
Multiple Airlines
Deal found 4/2![Multiple Airlines logo]()
$378
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1411:30 am
GCM
- SFO
3 stops35h 51m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$423
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/141:45 pm
GCM
- SFO
3 stops34h 10m
WestJet
Deal found 3/30![WestJet logo]()
$451
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/141:35 pm
GCM
- SFO
1 stop8h 35m
United Airlines
Deal found 4/1![United Airlines logo]()
$483
Find flight deals from Grand Cayman to San Francisco
Keep the following information in mind while searching for Grand Cayman to San Francisco flight deals. Data was last updated April 3, 2026.
Round-trip from | $735 (Air Canada) |
|---|---|
One-way from | $316 (Southwest) |
Cheapflights Fare Finder
Customize your flight search to find flights from Grand Cayman to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 3, 2026.
Use the filters below to find and compare flights from Grand Cayman to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
George TownSan Francisco
GCM - SFO
GCMSFO
George Town Owen Roberts Intl
Sat 6/13
10:55 am-9:10 pm
1 stop12h 15m
San Francisco
Wed 6/17
4:30 pm-11:25 am
1 stop16h 55m
$735
Quickest round-trip
George TownSan Francisco
GCM - SFO
GCMSFO
George Town Owen Roberts Intl
Sat 6/13
12:31 pm-10:38 pm
2 stops12h 07m
San Francisco
Wed 6/17
6:54 pm-11:30 am
2 stops14h 36m
$791
Cheapest one-way
George TownSan Francisco
GCM - SFO
GCMSFO
George Town Owen Roberts Intl
Tue 7/14
12:45 pm-12:10 am
2 stops13h 25m
$316
George TownSan Francisco
GCM - SFO
GCMSFO
George Town Owen Roberts Intl
Sat 5/16
1:25 pm-11:51 pm
1 stop12h 26m
$340
Quickest one-way
George TownSan Francisco
GCM - SFO
GCMSFO
George Town Owen Roberts Intl
Wed 4/22
1:05 pm-10:45 pm
2 stops11h 40m
$349
George TownSan Francisco
GCM - SFO
GCMSFO
George Town Owen Roberts Intl
Tue 7/14
11:30 am-9:21 pm
3 stops35h 51m
$423
George TownSan Francisco
GCM - SFO
GCMSFO
George Town Owen Roberts Intl
Wed 4/22
8:00 am-11:25 am
1 stop29h 25m
$448
George TownSan Francisco
GCM - SFO
GCMSFO
George Town Owen Roberts Intl
Tue 7/14
1:45 pm-9:55 pm
3 stops34h 10m
$451
Sorted by cheapest first
Best time to book a flight from Grand Cayman to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Grand Cayman with our price prediction graph.
GCM-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Grand Cayman to San Francisco
zzLAW-SFO
GCM-SFO
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated April 3, 2026.
Read reviews from past customers who have flown American Airlines from Grand Cayman to San Francisco. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.1
Crew
7.9
Comfort
7.2
Entertainment
6.9
Food
6.4
Boarding
7.5
Reviews
1 / 20
4.0
OkayElizabeth,Mar 2026
ORD - MIA
Overall
7.1
Crew
7.9
Comfort
7.2
Entertainment
6.9
Food
6.4
Boarding
7.5
Reviews
1 / 20
4.0
OkayElizabeth,Mar 2026
ORD - MIA
Related info for your journey
Find useful and relevant information for your journey from Grand Cayman to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
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San Bruno
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San Ramon
Sunnyvale
Vacaville
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Turlock
San Lorenzo
Davis
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Union City
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Foster City
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Grand Cayman and San Francisco flights
Browse other Grand Cayman and San Francisco flight options. Last updated on April 3, 2026.
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Top airline flying from Grand Cayman to San Francisco
Discover the top airline that operate flights from Grand Cayman to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$709 | Average$1,161 | FlexibilityNo cancel fee | On-time71% |