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$341+ Cheap flights from Grand Cayman to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/11. Fares are subject to change and may not be available on all flights or dates of travel.
GCM — SFO
Aug 25 — Sep 11
Mon 8/25
Mon 9/1
1 adult, Economy
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Cheap flight deals from Grand Cayman to San Francisco

Keep the following information in mind while searching for Grand Cayman to San Francisco flight deals. Data was last updated August 20, 2025.

Round-trip from

$564
(Southwest)

One-way from

$341
(FlightHub)

Popular in

October

Cheapest in

February

Average price

$808
From Grand Cayman to San Francisco
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One-way flight from Grand Cayman to San Francisco
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Highest demand for flights based on searches. 15% potential increase in price ($123 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($21 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Grand Cayman to San Francisco

Cheapest flights from Grand Cayman to San Francisco
Explore the most affordable flight options available from Grand Cayman to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 20, 2025.

This Southwest deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/141:30 pmGCM - SFO
2 stops13h 05mSouthwest
Sun 12/147:00 pmSFO - GCM
2 stops14h 35mSouthwest
Deal found 8/18$564
This MaxMilhas deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure MaxMilhas is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/143:45 pmGCM - SFO
1 stop31h 25mJetBlue
Sun 12/1410:32 pmSFO - GCM
1 stop12h 59mJetBlue
Deal found 8/18$627
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/44:45 pmGCM - SFO
2 stops30h 36mMultiple Airlines
Sun 9/710:17 pmSFO - GCM
1 stop14h 28mMultiple Airlines
Deal found 8/17$636
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/44:00 pmGCM - SFO
1 stop20h 43mMultiple Airlines
Wed 10/88:00 amSFO - GCM
2 stops28h 45mMultiple Airlines
Deal found 8/18$639
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/36:10 pmGCM - SFO
1 stop20h 30mMultiple Airlines
Sun 9/711:00 pmSFO - GCM
2 stops20h 20mMultiple Airlines
Deal found 8/17$679
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/112:02 pmGCM - SFO
1 stop13h 14mDelta
Sun 12/149:30 pmSFO - GCM
1 stop12h 07mDelta
Deal found 8/19$701
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/212:28 pmGCM - SFO
1 stop11h 23mAmerican Airlines
Thu 10/98:00 amSFO - GCM
1 stop9h 20mAmerican Airlines
Deal found 8/18$710
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/148:45 amGCM - SFO
2 stops14h 29mAmerican Airlines
Sat 12/1312:27 amSFO - GCM
1 stop13h 04mAmerican Airlines
Deal found 8/18$713
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/412:10 pmGCM - SFO
2 stops13h 15mAmerican Airlines
Wed 10/83:51 pmSFO - GCM
2 stops17h 19mAmerican Airlines
Deal found 8/18$715
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/112:50 pmGCM - SFO
2 stops24h 22mMultiple Airlines
Sat 12/1310:56 pmSFO - GCM
1 stop12h 04mMultiple Airlines
Deal found 8/19$721
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/135:45 pmGCM - SFO
1 stop9h 14mUnited Airlines
Sun 12/1412:43 amSFO - GCM
1 stop12h 47mUnited Airlines
Deal found 8/19$726

Cheapflights Fare Finder

 
Customize your flight search to find flights from Grand Cayman to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
Use the filters below to find and compare flights from Grand Cayman to San Francisco that are best for you.

Fly from

Grand Cayman

Fly to

San Francisco

Route

Depart

Return

Price

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Fri 11/14

1:30 pm-11:35 pm

2 stops13h 05m

San Francisco

Sun 12/14

7:00 pm-12:35 pm

2 stops14h 35m

$564

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Fri 11/14

3:45 pm-8:10 pm

1 stop31h 25m

San Francisco

Sun 12/14

10:32 pm-2:31 pm

1 stop12h 59m

$627

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Thu 9/4

4:45 pm-9:21 pm

2 stops30h 36m

San Francisco

Sun 9/7

10:17 pm-2:45 pm

1 stop14h 28m

$636

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Sat 10/4

4:00 pm-10:43 am

1 stop20h 43m

San Francisco

Wed 10/8

8:00 am-2:45 pm

2 stops28h 45m

$639

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Wed 9/3

6:10 pm-12:40 pm

1 stop20h 30m

San Francisco

Sun 9/7

11:00 pm-9:20 pm

2 stops20h 20m

$679

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Fri 12/12

5:45 pm-11:59 pm

1 stop9h 14m

San Francisco

Sat 12/13

12:43 am-4:30 pm

1 stop12h 47m

$701

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Thu 12/11

2:02 pm-10:52 pm

1 stop11h 50m

San Francisco

Mon 12/15

9:30 pm-12:37 pm

1 stop12h 07m

$701

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Thu 12/11

5:45 pm-12:10 pm

1 stop21h 25m

San Francisco

Sat 12/13

12:43 am-4:30 pm

1 stop12h 47m

$701

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Fri 12/12

5:45 pm-9:45 am

1 stop19h 00m

San Francisco

Tue 12/16

5:00 am-4:30 pm

1 stop8h 30m

$701

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Thu 9/11

12:50 pm-12:23 pm

2 stops25h 33m

$341

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/20

Showing 1-10 of 13 results
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Best time to book a flight from Grand Cayman to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Grand Cayman with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Grand Cayman to San Francisco

What is the cheapest month to book a flight from Grand Cayman to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Grand Cayman to San Francisco (average of $276). Flying from Grand Cayman to San Francisco in June is currently the most expensive (average of $358). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Grand Cayman to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from Grand Cayman?

    San Francisco (SFO), located 11.8 mi from the city center, is the airport you fly into when you book flights from Grand Cayman to San Francisco.

  • How long is the flight from Grand Cayman to San Francisco?

    There are many flights that can get you from Grand Cayman to San Francisco in 13h 05m. Fly via Southwest or JetBlue to get the fastest option. Grand Cayman and San Francisco are separated by a distance of 2764 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Grand Cayman to San Francisco that include hotel bookings?

    Yes. In addition to deals on Grand Cayman to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Grand Cayman to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Grand Cayman to San Francisco.

  • Can I find deals for business class flights from Grand Cayman to San Francisco?

    Yes. Cheapflights offers flight deals from Grand Cayman to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Grand Cayman to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Grand Cayman to San Francisco (average of $276). Flying from Grand Cayman to San Francisco in June is currently the most expensive (average of $358). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
Santa Cruz
Livermore
South San Francisco
Mountain View
Turlock
Santa Clara
Hollister
Antioch
Watsonville
Manteca
Newark
Milpitas
Sunnyvale
Campbell
Foster City
San Leandro
Burlingame
Redwood City
Vallejo

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