San Francisco

$316+ Cheap flights from Grand Cayman to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/14. Fares are subject to change and may not be available on all flights or dates of travel.
GCM — SFO
May 3 — May 101
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1. Tell us where you want to go

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Cheap flight deals from Grand Cayman to San Francisco

Cheapest flights from Grand Cayman to San Francisco
Explore the most affordable flight options available from Grand Cayman to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 3, 2026.

This Air Canada deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/1310:55 am
GCM
-
SFO
1 stop12h 15m
Air Canada
Wed 6/174:30 pm
SFO
-
GCM
1 stop16h 55m
Air Canada
Deal found 4/2$735
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/1312:31 pm
GCM
-
SFO
2 stops12h 07m
American Airlines
Wed 6/176:54 pm
SFO
-
GCM
2 stops14h 36m
American Airlines
Deal found 3/30$791

Find flight deals from Grand Cayman to San Francisco

Keep the following information in mind while searching for Grand Cayman to San Francisco flight deals. Data was last updated April 3, 2026.

Round-trip from

$735
(Air Canada)

One-way from

$316
(Southwest)
From Grand Cayman to San Francisco
One-way flight from Grand Cayman to San Francisco

Cheapflights Fare Finder

 
Customize your flight search to find flights from Grand Cayman to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 3, 2026.
Use the filters below to find and compare flights from Grand Cayman to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Sat 6/13

10:55 am-9:10 pm

1 stop12h 15m

San Francisco

Wed 6/17

4:30 pm-11:25 am

1 stop16h 55m

$735
Quickest round-trip

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Sat 6/13

12:31 pm-10:38 pm

2 stops12h 07m

San Francisco

Wed 6/17

6:54 pm-11:30 am

2 stops14h 36m

$791
Cheapest one-way

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Tue 7/14

12:45 pm-12:10 am

2 stops13h 25m

$316

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Sat 5/16

1:25 pm-11:51 pm

1 stop12h 26m

$340
Quickest one-way

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Wed 4/22

1:05 pm-10:45 pm

2 stops11h 40m

$349

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Tue 7/14

11:30 am-9:21 pm

3 stops35h 51m

$423

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Wed 4/22

8:00 am-11:25 am

1 stop29h 25m

$448

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

Tue 7/14

1:45 pm-9:55 pm

3 stops34h 10m

$451

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/29

Sorted by cheapest first

Best time to book a flight from Grand Cayman to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Grand Cayman with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Grand Cayman to San Francisco
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated April 3, 2026.
Read reviews from past customers who have flown American Airlines from Grand Cayman to San Francisco. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Overall

7.1

Crew

7.9

Comfort

7.2

Entertainment

6.9

Food

6.4

Boarding

7.5

Reviews

1 / 20
4.0
Okay

Elizabeth,Mar 2026

ORD - MIA

Staff was rude and flight attendants 2 out of 3 looked like they had just been thru a hurricane.

Overall

7.1

Crew

7.9

Comfort

7.2

Entertainment

6.9

Food

6.4

Boarding

7.5

Reviews

1 / 20
4.0
Okay

Elizabeth,Mar 2026

ORD - MIA

Staff was rude and flight attendants 2 out of 3 looked like they had just been thru a hurricane.

Related info for your journey

Find useful and relevant information for your journey from Grand Cayman to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to San Francisco from Grand Cayman?

    San Francisco (SFO), located 11.0 mi from the city center, is the airport you fly into when you book flights from Grand Cayman to San Francisco.

  • How long is the flight from Grand Cayman to San Francisco?

    There are many flights that can get you from Grand Cayman to San Francisco in 12h 07m. Fly via Air Canada or American Airlines to get the fastest option. Grand Cayman and San Francisco are separated by a distance of 2764 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Grand Cayman to San Francisco that include hotel bookings?

    Yes. In addition to deals on Grand Cayman to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Grand Cayman to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Grand Cayman to San Francisco.

  • Can I find deals for business class flights from Grand Cayman to San Francisco?

    Yes. Cheapflights offers flight deals from Grand Cayman to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
South San Francisco
Santa Cruz
Santa Clara
Livermore
Roseville
Rancho Cordova
San Bruno
Watsonville
San Ramon
Sunnyvale
Vacaville
San Carlos
Redwood City
Turlock
San Lorenzo
Davis
Manteca
Union City
Elk Grove
Foster City

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Alternative routes for Grand Cayman to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Grand Cayman to San Francisco

Discover the top airline that operate flights from Grand Cayman to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 3, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$709Average$1,161FlexibilityNo cancel feeOn-time71%

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