San Francisco

$247+ Cheap flights from Grand Cayman to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/11. Fares are subject to change and may not be available on all flights or dates of travel.
GCM — SFO
ene. 11 — ene. 181
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Cheap flight deals from Grand Cayman to San Francisco

Best flights from Grand Cayman to San Francisco
Discover carefully curated flight deals from Grand Cayman to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated diciembre 12, 2025.

This JetBlue deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/243:15 pmGCM - SFO
1 stop11h 43mJetBlue
dom. 3/111:30 pmSFO - GCM
1 stop12h 05mJetBlue
Deal found 12/10$411
This JetBlue deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/243:15 pmGCM - SFO
1 stop11h 43mJetBlue
lun. 3/210:39 pmSFO - GCM
1 stop12h 16mJetBlue
Deal found 12/10$411
This JetBlue deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 2/282:50 pmGCM - SFO
1 stop12h 08mJetBlue
dom. 3/111:30 pmSFO - GCM
1 stop12h 05mJetBlue
Deal found 12/10$411
This JetBlue deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 2/263:15 pmGCM - SFO
1 stop11h 43mJetBlue
dom. 3/111:30 pmSFO - GCM
1 stop12h 05mJetBlue
Deal found 12/11$437
This JetBlue deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 2/263:15 pmGCM - SFO
1 stop11h 43mJetBlue
lun. 3/210:39 pmSFO - GCM
1 stop12h 16mJetBlue
Deal found 12/11$437
This JetBlue deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/243:15 pmGCM - SFO
1 stop11h 43mJetBlue
mié. 3/411:30 pmSFO - GCM
1 stop12h 05mJetBlue
Deal found 12/10$444
This JetBlue deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 2/282:50 pmGCM - SFO
1 stop12h 08mJetBlue
mié. 3/411:30 pmSFO - GCM
1 stop12h 05mJetBlue
Deal found 12/10$444

Find flight deals from Grand Cayman to San Francisco

Keep the following information in mind while searching for Grand Cayman to San Francisco flight deals. Data was last updated diciembre 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$399
(Flysmarter)

One-way from

$247
(Kiwi.com)

Popular in

November

Cheapest in

February

Average price

$536
Provider with most accurate pricing for George Town Owen Roberts Intl-San Francisco flight deals.
Provider most trusted by Cheapflights users for George Town Owen Roberts Intl-San Francisco flights.
From Grand Cayman to San Francisco
One-way flight from Grand Cayman to San Francisco
Highest demand for flights based on searches. 22% potential increase in price ($205 potential increase over avg. RT price).
Cheapest flight prices on average. 14% potential price decrease ($87 potential savings vs. average RT price).
Average for round-trip flights in December 2025

Cheapflights Fare Finder

 
Customize your flight search to find flights from Grand Cayman to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 12, 2025.
Use the filters below to find and compare flights from Grand Cayman to San Francisco that are best for you.

Fly from

Grand Cayman

Fly to

San Francisco

Route

Depart

Return

Price

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

mar. 2/24

3:15 pm-11:58 pm

1 stop11h 43m

San Francisco

dom. 3/1

11:30 pm-2:35 pm

1 stop12h 05m

$411

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

mar. 2/24

3:15 pm-11:58 pm

1 stop11h 43m

San Francisco

lun. 3/2

10:39 pm-1:55 pm

1 stop12h 16m

$411

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

sáb. 2/28

2:50 pm-11:58 pm

1 stop12h 08m

San Francisco

dom. 3/1

11:30 pm-2:35 pm

1 stop12h 05m

$411

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

jue. 2/26

3:15 pm-11:58 pm

1 stop11h 43m

San Francisco

dom. 3/1

11:30 pm-2:35 pm

1 stop12h 05m

$437

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

jue. 2/26

3:15 pm-11:58 pm

1 stop11h 43m

San Francisco

lun. 3/2

10:39 pm-1:55 pm

1 stop12h 16m

$437

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

mar. 2/24

3:15 pm-11:58 pm

1 stop11h 43m

San Francisco

mié. 3/4

11:30 pm-2:35 pm

1 stop12h 05m

$444

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

sáb. 2/28

2:50 pm-11:58 pm

1 stop12h 08m

San Francisco

mié. 3/4

11:30 pm-2:35 pm

1 stop12h 05m

$444

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

mar. 1/13

3:30 pm-11:29 pm

1 stop10h 59m

$250

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

mar. 1/13

1:30 pm-10:34 am

2 stops24h 04m

$338

George TownSan Francisco

GCM - SFO

GCMSFO

George Town Owen Roberts Intl

vie. 1/9

3:40 pm-5:09 pm

1 stop28h 29m

$349

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 17 results
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Best time to book a flight from Grand Cayman to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Grand Cayman with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Grand Cayman to San Francisco
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated diciembre 12, 2025.
Read reviews from past customers who have flown American Airlines from Grand Cayman to San Francisco. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

7.5

Food

6.5

Entertainment

6.9

Crew

8.0

Comfort

7.2

Overall

7.2

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

Boarding

7.5

Food

6.5

Entertainment

6.9

Crew

8.0

Comfort

7.2

Overall

7.2

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

Related info for your journey

Find useful and relevant information for your journey from Grand Cayman to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to San Francisco from Grand Cayman?

    San Francisco (SFO), located 11.8 mi from the city center, is the airport you fly into when you book flights from Grand Cayman to San Francisco.

  • How long is the flight from Grand Cayman to San Francisco?

    There are many flights that can get you from Grand Cayman to San Francisco in 11h 43m. Fly via JetBlue to get the fastest option. Grand Cayman and San Francisco are separated by a distance of 2764 mi.

  • Can I find deals for flights from Grand Cayman to San Francisco that include hotel bookings?

    Yes. In addition to deals on Grand Cayman to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Grand Cayman to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Grand Cayman to San Francisco.

  • Can I find deals for business class flights from Grand Cayman to San Francisco?

    Yes. Cheapflights offers flight deals from Grand Cayman to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
South San Francisco
Santa Cruz
Livermore
Turlock
Manteca
Watsonville
Sunnyvale
Santa Clara
San Bruno
Redwood City
Daly City
Vallejo
Hollister
Foster City
Union City
Davis
San Ramon
Burlingame
Milpitas

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Alternative routes for Grand Cayman to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Grand Cayman to San Francisco

Discover the top airline that operate flights from Grand Cayman to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$709Average$1,478FlexibilityNo cancel feeOn-time71%

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