What’s the top layover airport for flights from Istanbul Airport to San Francisco?

London (LHR) – chosen by Cheapflights users on 87% of 1-stop itineraries from Istanbul Airport to San Francisco on Cheapflights.

What day of the week experiences the fewest flight delays on this route?

Tuesday tends to have the lowest number of delays on this route, whereas Wednesday has historically faced a higher average of delays compared to other days of the week.

What’s the cheapest layover airport for flights from Istanbul Airport to San Francisco?

London (LHR) is the most affordable 1-stop option, with an average round-trip price of $621.

Which airline has the best punctuality record on Istanbul to San Francisco flights?

Over the last year, Turkish Airlines have had the lowest number of delays on this route, with just 22% of flights being delayed.

How often are flights from Istanbul to San Francisco delayed?

About 22% of weekly flights between Istanbul and San Francisco have experienced delays in the past year, with the average delay time being 89 minutes.

What’s the fastest layover option from Istanbul Airport to San Francisco?

Flights via Frankfurt am Main (FRA) have the shortest average one-way travel time for 1-stop routes: 16h 10m.

What is the most punctual flight time for Istanbul to San Francisco flights?

Historically, flights departing in the morning are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.

Which airport typically offers the quickest layover for flights from Istanbul Airport to San Francisco?

Flights via Frankfurt am Main (FRA) offer the fastest connection on this route, with an average layover time of 2h 56m.

How long is the flight from Istanbul Airport to San Francisco?

Departing from Istanbul Airport to San Francisco will take you 33h 33m. The distance from Istanbul Airport to San Francisco is about 6684 mi.

What are the cheapest airlines flying from Istanbul Airport to San Francisco round-trip?

Our cheapest airline available from Istanbul Airport to San Francisco is KLM. Our recent data shows that you can find tickets from as low as $445 on this airline. Additional options worth looking into are American Airlines and British Airways, starting at $490 and $506 round-trip. These flights start at 43% lower than the current average price 3 months from now.

What are the cheapest airlines to fly from Istanbul Airport to San Francisco one-way?

The cheapest airline one-way is British Airways, with whom users have recently found tickets for as low as $376. However, be on the lookout for offers from American Airlines and Qatar Airways, as they are both options that can get you from Istanbul Airport to San Francisco for a low price.

Weekly flight availability from Istanbul Airport to San Francisco

The most flights from IST to SFO are scheduled on a Tuesday (6 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (3 on average).

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

What are the cheapest flights from Istanbul Airport to San Francisco?

Looking for the cheapest flight from Istanbul Airport to San Francisco? While on average our users pay $1,019, our data indicates the cheapest price to be $667. The most popular route (Istanbul - San Francisco), is priced around $556.

What are the most reliable airlines from Istanbul Airport to San Francisco?

The top 3 most reliable airlines when flying from Istanbul Airport to San Francisco are Turkish Airlines (73%), Pakistan International Airlines (73%) and IndiGo (73%).

What are the most popular airlines that fly from Istanbul Airport to San Francisco?

Before booking your flight from Istanbul Airport to San Francisco check out the most popular airlines for this route: Turkish Airlines, Lufthansa or British Airways.

Where are the most common layover locations when flying from Istanbul Airport to San Francisco?

The most popular layover on flights from Istanbul Airport to San Francisco is Frankfurt am Main.

Where are the least popular layover locations for Istanbul Airport to San Francisco flights?

Of the flights from Istanbul Airport to San Francisco that have layovers, the fewest flights stop in London.

What are some popular things to do or see while on a layover in Frankfurt am Main?

Römerberg, Konstablerwache, and Festhalle are the most popular attractions in Frankfurt am Main if you're in need of something to do during your layover. Those on a layover in Frankfurt am Main interested in visiting Römerberg, Konstablerwache, or Festhalle can do so by traveling 7.4 mi, 7.7 mi, and 6.5 mi, respectively from Frankfurt am Main. Those looking to explore during their layover in Frankfurt am Main can rent a car from Frankfurt am Main for about $43 per day.

Most accurate provider : When it comes to deals on Istanbul Airport-San Francisco flights, users find the pricing of Justfly.com to be most consistent on Cheapflights vs. Justfly.com Users can find the same prices on Istanbul Airport-San Francisco flight deals on Cheapflights vs. Justfly.com >95% of the time. Price accuracy is based on data collected from Istanbul Airport-San Francisco flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Istanbul Airport-San Francisco flights, Cheapflights users trust Justfly.com the most. Justfly.com has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Istanbul Airport-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

What airport do you fly into for flights to San Francisco from Istanbul?

For a flight from Istanbul to San Francisco, you will be flying into San Francisco. San Francisco (SFO) is just 11.8 mi from the center of the city. San Francisco is the only San Francisco airport and it handles 4 inbound flights from Istanbul per day. 7 airlines have flights to San Francisco from Istanbul on a regular basis.

Can I find deals for flights from Istanbul to San Francisco that include hotel bookings?

Yes. In addition to deals on Istanbul to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Istanbul to San Francisco?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Istanbul to San Francisco.

Can I find deals for business class flights from Istanbul to San Francisco?

Yes. Cheapflights offers flight deals from Istanbul to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$602+ Flights from Istanbul Airport to San Francisco

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1. Tell us where you want to go

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Cheapflights Tip: The best prices from Istanbul to San Francisco are usually found in March or December, booked 79 days in advance, depart on a Thursday or Monday and return on a Monday

Cheap flight deals from Istanbul to San Francisco

Cheapest flights from Istanbul to San Francisco
Explore the most affordable flight options available from Istanbul to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 31, 2025.

Sun 12/289:20 pmIST - SFO

2 stops32h 17mBritish Airways

Sat 3/144:59 pmSFO - IST

2 stops22h 11mBritish Airways

Deal found 12/28

$942

Wed 12/316:30 amIST - SFO

2 stops28h 56mUnited Airlines

Fri 1/307:25 amSFO - IST

2 stops23h 40mUnited Airlines

Deal found 12/30

$1,091

Sun 12/289:20 pmIST - SFO

2 stops32h 17mMultiple Airlines

Thu 1/15:30 pmSFO - IST

1 stop36h 55mMultiple Airlines

Deal found 12/28

$1,374

Wed 12/315:55 pmIST - SFO

1 stop28h 55mDelta

Fri 1/303:40 pmSFO - IST

1 stop25h 10mDelta

Deal found 12/30

$1,402

Wed 12/311:50 pmIST - SFO

Nonstop13h 55mTurkish Airlines

Fri 1/306:50 pmSFO - IST

Nonstop13h 10mTurkish Airlines

Deal found 12/30

$1,722

Tue 12/302:00 amIST - SFO

2 stops21h 40mMultiple Airlines

Fri 1/307:30 amSFO - IST

3 stops33h 20mMultiple Airlines

Deal found 12/30

$1,767

Best flights from Istanbul to San Francisco
Discover carefully curated flight deals from Istanbul to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 31, 2025.

Mon 3/235:55 pmIST - SFO

2 stops33h 33mDelta

Mon 5/118:55 amSFO - IST

2 stops30h 25mDelta

Deal found 12/28

$658

Tue 3/176:30 amIST - SFO

1 stop24h 40mUnited Airlines

Wed 4/292:40 pmSFO - IST

1 stop20h 45mUnited Airlines

Deal found 12/30

$675

Thu 2/265:55 pmIST - SFO

2 stops34h 53mDelta

Sat 3/79:50 amSFO - IST

2 stops20h 05mDelta

Deal found 12/29

$659

Mon 1/125:55 pmIST - SFO

2 stops40h 09mDelta

Tue 3/102:55 pmSFO - IST

1 stop16h 00mDelta

Deal found 12/29

$660

Sat 1/36:30 amIST - SFO

2 stops28h 33mUnited Airlines

Mon 3/167:50 pmSFO - IST

1 stop16h 55mUnited Airlines

Deal found 12/30

$751

Fri 3/274:50 amIST - SFO

2 stops23h 42mDelta

Sat 5/91:45 pmSFO - IST

1 stop25h 35mDelta

Deal found 12/28

$664

Thu 3/264:50 amIST - SFO

2 stops25h 35mDelta

Sat 5/91:45 pmSFO - IST

1 stop25h 35mDelta

Deal found 12/28

$664

Tue 2/245:55 pmIST - SFO

2 stops33h 14mDelta

Wed 3/118:55 pmSFO - IST

2 stops44h 55mDelta

Deal found 12/29

$665

Thu 2/264:50 amIST - SFO

2 stops27h 21mDelta

Wed 3/118:55 pmSFO - IST

2 stops44h 55mDelta

Deal found 12/29

$671

Sun 3/225:55 pmIST - SFO

1 stop28h 55mDelta

Thu 5/211:45 pmSFO - IST

1 stop25h 35mDelta

Deal found 12/28

$678

Mon 1/125:55 pmIST - SFO

1 stop28h 55mDelta

Fri 1/231:55 pmSFO - IST

1 stop16h 00mDelta

Deal found 12/29

$680

Last-minute flights from Istanbul to San Francisco
Discover last-minute flight deals from Istanbul to San Francisco. Data last updated December 31, 2025 and is based on user searches.

Mon 1/125:55 pmIST - SFO

2 stops40h 09mDelta

Thu 1/221:55 pmSFO - IST

1 stop16h 00mDelta

Deal found 12/29

$660

Mon 1/125:55 pmIST - SFO

1 stop28h 55mDelta

Fri 1/231:55 pmSFO - IST

1 stop16h 00mDelta

Deal found 12/29

$680

Thu 1/154:50 amIST - SFO

2 stops27h 08mDelta

Mon 2/238:55 amSFO - IST

2 stops21h 00mDelta

Deal found 12/28

$665

Thu 1/154:50 amIST - SFO

2 stops27h 08mDelta

Thu 2/263:40 pmSFO - IST

1 stop25h 10mDelta

Deal found 12/28

$671

Thu 1/154:50 amIST - SFO

2 stops27h 08mDelta

Wed 2/259:10 amSFO - IST

2 stops31h 40mDelta

Deal found 12/28

$681

Thu 1/154:50 amIST - SFO

2 stops27h 08mDelta

Sat 2/281:55 pmSFO - IST

1 stop16h 00mDelta

Deal found 12/28

$695

Sat 1/174:50 amIST - SFO

2 stops23h 57mKLM

Thu 2/261:55 pmSFO - IST

1 stop16h 00mKLM

Deal found 12/28

$692

Mon 1/195:55 pmIST - SFO

2 stops34h 52mDelta

Tue 2/1010:30 amSFO - IST

2 stops30h 20mDelta

Deal found 12/28

$679

Mon 1/195:55 pmIST - SFO

2 stops34h 52mDelta

Thu 2/121:55 pmSFO - IST

1 stop16h 00mDelta

Deal found 12/28

$686

Tue 1/205:55 pmIST - SFO

2 stops34h 52mKLM

Wed 2/2511:02 amSFO - IST

2 stops18h 53mKLM

Deal found 12/28

$656

Wed 1/215:55 pmIST - SFO

2 stops33h 14mDelta

Mon 2/235:55 amSFO - IST

2 stops24h 00mDelta

Deal found 12/28

$659

One-way flights from Istanbul to San Francisco
Search for one-way flight options from Istanbul to San Francisco. Find affordable one-way fares based on user searches. Data last updated December 31, 2025.

Fri 1/308:10 pmIST - SFO

1 stop27h 30mQatar Airways

Deal found 12/28

$602

Wed 3/257:20 pmIST - SFO

3 stops36h 18mMultiple Airlines

Deal found 12/28

$604

Thu 1/221:50 pmIST - SFO

1 stop33h 50mQatar Airways

Deal found 12/29

$608

Fri 2/68:10 pmIST - SFO

1 stop27h 30mQatar Airways

Deal found 12/30

$616

Thu 3/268:10 pmIST - SFO

1 stop27h 30mQatar Airways

Deal found 12/28

$622

Sat 1/318:10 pmIST - SFO

1 stop27h 30mQatar Airways

Deal found 12/28

$624

Fri 1/2312:00 pmIST - SFO

1 stop35h 40mQatar Airways

Deal found 12/29

$627

Thu 3/267:35 amIST - SFO

2 stops23h 12mBritish Airways

Deal found 12/28

$634

Fri 3/278:10 pmIST - SFO

1 stop27h 30mQatar Airways

Deal found 12/28

$641

Sun 1/258:05 amIST - SFO

Nonstop14h 00mTurkish Airlines

Deal found 12/30

$666

Sat 1/243:50 amIST - SFO

2 stops27h 20mMultiple Airlines

Deal found 12/30

$670

Find flight deals from Istanbul to San Francisco

Most accurate provider	Justfly.com 3 stars
Most trusted provider	Justfly.com 3 stars
Round-trip from	$656 (Air France)
One-way from	$602 (SmartFares)
Popular in	July
Cheapest in	March
Average price	$691
Good round-trip deal	$844 or less
Good one-way deal	$695 or less

Provider with most accurate pricing for Istanbul-San Francisco flight deals.

Search Deals

Provider most trusted by Cheapflights users for Istanbul-San Francisco flights.

Search Deals

From Istanbul to San Francisco

Search Deals

One-way flight from Istanbul to San Francisco

Search Deals

Highest demand for flights based on searches. 11% potential increase in price ($100 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($19 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Price to beat on a round-trip flight from Istanbul to San Francisco.

Search Deals

Price to beat on a one-way flight from Istanbul to San Francisco.

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Istanbul Airport to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

IstanbulSan Francisco

IST - SFO

ISTSFO

Istanbul

Mon 3/23

5:55 pm-5:28 pm

2 stops33h 33m

San Francisco

Mon 5/11

8:55 am-1:20 am

2 stops30h 25m

$658

IstanbulSan Francisco

IST - SFO

ISTSFO

Istanbul

Thu 2/26

5:55 pm-5:48 pm

2 stops34h 53m

San Francisco

Sat 3/7

9:50 am-4:55 pm

2 stops20h 05m

$659

IstanbulSan Francisco

IST - SFO

ISTSFO

Istanbul

Mon 1/12

5:55 pm-11:04 pm

2 stops40h 09m

San Francisco

Tue 3/10

2:55 pm-4:55 pm

1 stop16h 00m

$660

IstanbulSan Francisco

IST - SFO

ISTSFO

Istanbul

Fri 3/27

4:50 am-6:32 pm

2 stops23h 42m

San Francisco

Sat 5/9

1:45 pm-1:20 am

1 stop25h 35m

$664

IstanbulSan Francisco

IST - SFO

ISTSFO

Istanbul

Thu 3/26

4:50 am-8:25 pm

2 stops25h 35m

San Francisco

Sat 5/9

1:45 pm-1:20 am

1 stop25h 35m

$664

IstanbulSan Francisco

IST - SFO

ISTSFO

Istanbul

Tue 2/24

5:55 pm-4:09 pm

2 stops33h 14m

San Francisco

Wed 3/11

8:55 pm-3:50 am

2 stops44h 55m

$665

IstanbulSan Francisco

IST - SFO

ISTSFO

Istanbul

Thu 2/26

4:50 am-9:11 pm

2 stops27h 21m

San Francisco

Wed 3/11

8:55 pm-3:50 am

2 stops44h 55m

$671

IstanbulSan Francisco

IST - SFO

ISTSFO

Istanbul

Tue 3/17

6:30 am-9:10 pm

1 stop24h 40m

San Francisco

Wed 4/29

2:40 pm-9:25 pm

1 stop20h 45m

$675

IstanbulSan Francisco

IST - SFO

ISTSFO

Istanbul

Sun 3/22

5:55 pm-12:50 pm

1 stop28h 55m

San Francisco

Thu 5/21

1:45 pm-1:20 am

1 stop25h 35m

$678

IstanbulSan Francisco

IST - SFO

ISTSFO

Istanbul

Mon 1/12

5:55 pm-11:50 am

1 stop28h 55m

San Francisco

Fri 1/23

1:55 pm-4:55 pm

1 stop16h 00m

$680

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/30

Showing 1-10 of 23 results

Compare providers for flights from Istanbul to San Francisco

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Istanbul to San Francisco in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars
Cheapflightsfares	Price Accuracy3 stars	Trust Score*2 stars
Justfly.com	Price Accuracy3 stars	Trust Score*3 stars
AranGrant	Price Accuracy2 stars	Trust Score*3 stars
Priceline	Price Accuracy1 star	Trust Score*3 stars
Kiwi.com	Price Accuracy3 stars	Trust Score*3 stars
OneTravel	Price Accuracy3 stars	Trust Score*3 stars
Gurufare	Price Accuracy2 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Istanbul Airport-San Francisco flights, users find the pricing of Justfly.com to be most consistent on Cheapflights vs. Justfly.com Users can find the same prices on Istanbul Airport-San Francisco flight deals on Cheapflights vs. Justfly.com >95% of the time. Price accuracy is based on data collected from Istanbul Airport-San Francisco flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Istanbul Airport-San Francisco flights, Cheapflights users trust Justfly.com the most. Justfly.com has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Istanbul Airport-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Istanbul to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Istanbul with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Istanbul Airport to San Francisco

Prices

Airlines

Delays

How far ahead should I book a flight from Istanbul Airport to San Francisco?

The best time to book flights from Istanbul Airport to San Francisco is 79 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Istanbul Airport to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Istanbul Airport to San Francisco (average of $476). Flying from Istanbul Airport to San Francisco in August is currently the most expensive (average of $626). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IST to SFO?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Istanbul Airport to San Francisco as you normally would.

Reviews of airlines servicing San Francisco

Peruse reviews from past customers who have flown with KLM, United Airlines, and Turkish Airlines from Istanbul Airport to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

KLM

7.7

Good

1,435 reviews

Reviews

1 / 20

8.0

Excellent

Anonymous,Dec 2025

YYC - AMS

Not literally sitting in the very last row in the middle

KLM

7.7

Good

1,435 reviews

KLM

7.7

Good

1,435 reviews

Reviews

1 / 20

8.0

Excellent

Anonymous,Dec 2025

YYC - AMS

Not literally sitting in the very last row in the middle

United Airlines

7.4

Good

9,123 reviews

KLM

7.7

Good

1,435 reviews

Reviews

1 / 20

8.0

Excellent

Anonymous,Dec 2025

YYC - AMS

Not literally sitting in the very last row in the middle

Turkish Airlines

7.3

Good

4,133 reviews

KLM

7.7

Good

1,435 reviews

Reviews

1 / 20

8.0

Excellent

Anonymous,Dec 2025

YYC - AMS

Not literally sitting in the very last row in the middle

Lufthansa

6.8

Okay

7,668 reviews

KLM

7.7

Good

1,435 reviews

Reviews

1 / 20

8.0

Excellent

Anonymous,Dec 2025

YYC - AMS

Not literally sitting in the very last row in the middle

British Airways

6.7

Okay

7,630 reviews

KLM

7.7

Good

1,435 reviews

Reviews

1 / 20

8.0

Excellent

Anonymous,Dec 2025

YYC - AMS

Not literally sitting in the very last row in the middle

Related info for your journey

What airport do you fly into for flights to San Francisco from Istanbul?
For a flight from Istanbul to San Francisco, you will be flying into San Francisco. San Francisco (SFO) is just 11.8 mi from the center of the city. San Francisco is the only San Francisco airport and it handles 4 inbound flights from Istanbul per day. 7 airlines have flights to San Francisco from Istanbul on a regular basis.
How long is the flight from Istanbul Airport to San Francisco?
Departing from Istanbul Airport to San Francisco will take you 33h 33m. The distance from Istanbul Airport to San Francisco is about 6684 mi.
What are the cheapest airlines flying from Istanbul Airport to San Francisco round-trip?
Our cheapest airline available from Istanbul Airport to San Francisco is KLM. Our recent data shows that you can find tickets from as low as $445 on this airline. Additional options worth looking into are American Airlines and British Airways, starting at $490 and $506 round-trip. These flights start at 43% lower than the current average price 3 months from now.
What are the cheapest airlines to fly from Istanbul Airport to San Francisco one-way?
The cheapest airline one-way is British Airways, with whom users have recently found tickets for as low as $376. However, be on the lookout for offers from American Airlines and Qatar Airways, as they are both options that can get you from Istanbul Airport to San Francisco for a low price.
What are the most reliable airlines from Istanbul Airport to San Francisco?
The top 3 most reliable airlines when flying from Istanbul Airport to San Francisco are Turkish Airlines (73%), Pakistan International Airlines (73%) and IndiGo (73%).
What are the cheapest flights from Istanbul Airport to San Francisco?
Looking for the cheapest flight from Istanbul Airport to San Francisco? While on average our users pay $1,019, our data indicates the cheapest price to be $667. The most popular route (Istanbul - San Francisco), is priced around $556.
Where are the most common layover locations when flying from Istanbul Airport to San Francisco?
The most popular layover on flights from Istanbul Airport to San Francisco is Frankfurt am Main.
What are some popular things to do or see while on a layover in Frankfurt am Main?
Römerberg, Konstablerwache, and Festhalle are the most popular attractions in Frankfurt am Main if you're in need of something to do during your layover. Those on a layover in Frankfurt am Main interested in visiting Römerberg, Konstablerwache, or Festhalle can do so by traveling 7.4 mi, 7.7 mi, and 6.5 mi, respectively from Frankfurt am Main. Those looking to explore during their layover in Frankfurt am Main can rent a car from Frankfurt am Main for about $43 per day.
Where are the least popular layover locations for Istanbul Airport to San Francisco flights?
Of the flights from Istanbul Airport to San Francisco that have layovers, the fewest flights stop in London.
Can I find deals for flights from Istanbul to San Francisco that include hotel bookings?
Yes. In addition to deals on Istanbul to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Istanbul to San Francisco?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Istanbul to San Francisco.
Can I find deals for business class flights from Istanbul to San Francisco?
Yes. Cheapflights offers flight deals from Istanbul to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Istanbul Airport to San Francisco?
Currently, January is the cheapest month in which you can book a flight from Istanbul Airport to San Francisco (average of $476). Flying from Istanbul Airport to San Francisco in August is currently the most expensive (average of $626). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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South San Francisco

Santa Cruz

Livermore

Santa Clara

Watsonville

Redwood City

Sunnyvale

San Bruno

Daly City

Manteca

Turlock

San Carlos

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Foster City

Union City

Davis

Emeryville

Browse thousands of different options on Cheapflights for your next trip

Top 7 airlines flying from Istanbul to San Francisco

Airline	Cheapest	Average	Flexibility	On-time
KLM	Cheapest$445	Average$576	FlexibilityNo cancel fee	On-time75%
American Airlines	Cheapest$490	Average$660	FlexibilityNo cancel fee	On-time71%
British Airways	Cheapest$506	Average$627	FlexibilityNo cancel fee	On-time70%
United Airlines	Cheapest$590	Average$688	FlexibilityNo cancel fee	On-time69%
Lufthansa	Cheapest$603	Average$771	FlexibilityNo cancel fee	On-time76%
Turkish Airlines	Cheapest$628	Average$860	FlexibilityNo cancel fee	On-time77%
Delta	Cheapest$647	Average$696	FlexibilityNo cancel fee	On-timeN/A

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$602+ Cheap flights from Istanbul (IST) to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/30. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Istanbul to San Francisco with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Istanbul to San Francisco are usually found in March or December, booked 79 days in advance, depart on a Thursday or Monday and return on a Monday

Cheap flight deals from Istanbul to San Francisco

Cheapest flights from Istanbul to San FranciscoExplore the most affordable flight options available from Istanbul to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 31, 2025.

Explore the most affordable flight options available from Istanbul to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 31, 2025.

Find flight deals from Istanbul to San Francisco

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Use the filters below to find and compare flights from Istanbul Airport to San Francisco that are best for you.

Compare providers for flights from Istanbul to San Francisco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Istanbul to San Francisco in December.

Best time to book a flight from Istanbul to San Francisco

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Cheapflights Insights

Everything you need to know about your flight from Istanbul Airport to San Francisco

How far ahead should I book a flight from Istanbul Airport to San Francisco?

What is the cheapest month to book a flight from Istanbul Airport to San Francisco?

What is the cheapest time of day to fly from IST to SFO?

Weekly flight availability from Istanbul Airport to San Francisco

How often are flights from Istanbul to San Francisco delayed?

What is the most punctual flight time for Istanbul to San Francisco flights?

What day of the week experiences the fewest flight delays on this route?

Which airline has the best punctuality record on Istanbul to San Francisco flights?

What’s the top layover airport for flights from Istanbul Airport to San Francisco?

What’s the cheapest layover airport for flights from Istanbul Airport to San Francisco?

What’s the fastest layover option from Istanbul Airport to San Francisco?

Which airport typically offers the quickest layover for flights from Istanbul Airport to San Francisco?

Reviews of airlines servicing San Francisco

Peruse reviews from past customers who have flown with KLM, United Airlines, and Turkish Airlines from Istanbul Airport to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Istanbul to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to San Francisco from Istanbul?

How long is the flight from Istanbul Airport to San Francisco?

What are the cheapest airlines flying from Istanbul Airport to San Francisco round-trip?

What are the cheapest airlines to fly from Istanbul Airport to San Francisco one-way?

What are the most reliable airlines from Istanbul Airport to San Francisco?

What are the cheapest flights from Istanbul Airport to San Francisco?

Where are the most common layover locations when flying from Istanbul Airport to San Francisco?

What are some popular things to do or see while on a layover in Frankfurt am Main?

Where are the least popular layover locations for Istanbul Airport to San Francisco flights?

Can I find deals for flights from Istanbul to San Francisco that include hotel bookings?

How can I find direct flights from Istanbul to San Francisco?

Can I find deals for business class flights from Istanbul to San Francisco?

What is the cheapest month to book a flight from Istanbul Airport to San Francisco?

Traveling to a place near San Francisco?

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Alternative routes for Istanbul to San Francisco

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Top 7 airlines flying from Istanbul to San Francisco

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Cheapest flights from Istanbul to San Francisco
Explore the most affordable flight options available from Istanbul to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 31, 2025.