$324+ Cheap flights from Santo Domingo (SDQ) to San Antonio (SAT)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/4. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — SAT
Apr 30 — May 71
Round-trip
1 adult, Economy
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Santo Domingo to San Antonio
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Best
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One-way
Cheapest flights from Santo Domingo to San AntonioExplore the most affordable flight options available from Santo Domingo to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2026.
Explore the most affordable flight options available from Santo Domingo to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/252:35 pm
SDQ
- SAT
1 stop10h 16m
Spirit Airlines
Sat 5/26:00 am
SAT
- SDQ
1 stop6h 29m
Spirit Airlines
Deal found 3/26![Spirit Airlines logo]()
$429
This eDestinos deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/22:52 am
SDQ
- SAT
1 stop7h 35m
Spirit Airlines
Tue 4/710:22 am
SAT
- SDQ
1 stop14h 16m
Spirit Airlines
Deal found 3/27![Spirit Airlines logo]()
$440
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/62:52 am
SDQ
- SAT
1 stop7h 35m
Spirit Airlines
Tue 4/1410:22 am
SAT
- SDQ
1 stop26h 07m
Spirit Airlines
Deal found 3/27![Spirit Airlines logo]()
$472
This eDestinos deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/12:52 am
SDQ
- SAT
1 stop7h 35m
Spirit Airlines
Tue 4/710:22 am
SAT
- SDQ
1 stop14h 16m
Spirit Airlines
Deal found 3/27![Spirit Airlines logo]()
$497
This Mytrip deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/62:52 am
SDQ
- SAT
3 stops34h 35m
Multiple Airlines
Tue 4/1410:22 am
SAT
- SDQ
3 stops29h 07m
Multiple Airlines
Deal found 3/27![Multiple Airlines logo]()
$535
Best flights from Santo Domingo to San AntonioDiscover carefully curated flight deals from Santo Domingo to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 31, 2026.
Discover carefully curated flight deals from Santo Domingo to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 31, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/252:35 pm
SDQ
- SAT
1 stop10h 16m
Spirit Airlines
Sat 5/26:00 am
SAT
- SDQ
1 stop6h 29m
Spirit Airlines
Deal found 3/26![Spirit Airlines logo]()
$429
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:35 pm
SDQ
- SAT
2 stops16h 28m
Delta
Sat 6/61:33 pm
SAT
- SDQ
1 stop10h 08m
Delta
Deal found 3/27![Delta logo]()
$682
This American Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/117:00 am
SDQ
- SAT
1 stop17h 25m
American Airlines
Mon 8/315:06 am
SAT
- SDQ
1 stop14h 24m
American Airlines
Deal found 3/28![American Airlines logo]()
$701
This United Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/113:20 pm
SDQ
- SAT
2 stops21h 51m
United Airlines
Mon 8/315:30 am
SAT
- SDQ
2 stops16h 16m
United Airlines
Deal found 3/28![United Airlines logo]()
$759
This Mytrip deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1112:45 pm
SDQ
- SAT
2 stops21h 20m
Multiple Airlines
Sat 8/1511:15 am
SAT
- SDQ
3 stops23h 35m
Multiple Airlines
Deal found 3/26![Multiple Airlines logo]()
$885
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1110:25 am
SDQ
- SAT
1 stop14h 00m
American Airlines
Sat 8/155:00 am
SAT
- SDQ
2 stops12h 20m
American Airlines
Deal found 3/26![American Airlines logo]()
$703
This Mytrip deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/112:45 pm
SDQ
- SAT
2 stops21h 20m
Multiple Airlines
Thu 7/94:05 pm
SAT
- SDQ
2 stops12h 54m
Multiple Airlines
Deal found 3/26![Multiple Airlines logo]()
$893
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/110:25 am
SDQ
- SAT
1 stop14h 34m
American Airlines
Thu 7/98:00 am
SAT
- SDQ
2 stops13h 59m
American Airlines
Deal found 3/26![American Airlines logo]()
$825
Last-minute flights from Santo Domingo to San AntonioDiscover last-minute flight deals from Santo Domingo to San Antonio. Data last updated March 31, 2026 and is based on user searches.
Discover last-minute flight deals from Santo Domingo to San Antonio. Data last updated March 31, 2026 and is based on user searches.
This eDestinos deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/12:52 am
SDQ
- SAT
1 stop7h 35m
Spirit Airlines
Tue 4/710:22 am
SAT
- SDQ
1 stop14h 16m
Spirit Airlines
Deal found 3/27![Spirit Airlines logo]()
$497
This eDestinos deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/22:52 am
SDQ
- SAT
1 stop7h 35m
Spirit Airlines
Tue 4/710:22 am
SAT
- SDQ
1 stop14h 16m
Spirit Airlines
Deal found 3/27![Spirit Airlines logo]()
$440
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/62:52 am
SDQ
- SAT
1 stop7h 35m
Spirit Airlines
Tue 4/1410:22 am
SAT
- SDQ
1 stop26h 07m
Spirit Airlines
Deal found 3/27![Spirit Airlines logo]()
$472
This Mytrip deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/62:52 am
SDQ
- SAT
3 stops34h 35m
Multiple Airlines
Tue 4/1410:22 am
SAT
- SDQ
3 stops29h 07m
Multiple Airlines
Deal found 3/27![Multiple Airlines logo]()
$535
This Cheapflightsfares deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/252:35 pm
SDQ
- SAT
1 stop10h 16m
Spirit Airlines
Sat 5/26:00 am
SAT
- SDQ
1 stop6h 29m
Spirit Airlines
Deal found 3/26![Spirit Airlines logo]()
$429
One-way flights from Santo Domingo to San AntonioSearch for one-way flight options from Santo Domingo to San Antonio. Find affordable one-way fares based on user searches. Data last updated March 31, 2026.
Search for one-way flight options from Santo Domingo to San Antonio. Find affordable one-way fares based on user searches. Data last updated March 31, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/42:52 am
SDQ
- SAT
1 stop7h 35m
Spirit Airlines
Deal found 3/27![Spirit Airlines logo]()
$324
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/42:52 am
SDQ
- SAT
3 stops46h 27m
Multiple Airlines
Deal found 3/27![Multiple Airlines logo]()
$341
Find flight deals from Santo Domingo to San Antonio
Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to San Antonio (SAT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 31, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $429 (Cheapflightsfares) |
One-way from | $324 (Kiwi.com) |
Popular in | April |
Cheapest in | December |
Average price | $531 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santo Domingo to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2026.
Use the filters below to find and compare flights from Santo Domingo to San Antonio that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Santo DomingoSan Antonio
SDQ - SAT
SDQSAT
Santo Domingo Las Americas
Sat 4/25
2:35 pm-11:51 pm
1 stop10h 16m
San Antonio
Sat 5/2
6:00 am-1:29 pm
1 stop6h 29m
$429
Santo DomingoSan Antonio
SDQ - SAT
SDQSAT
Santo Domingo Las Americas
Tue 5/26
7:35 pm-11:03 am
2 stops16h 28m
San Antonio
Sat 6/6
1:33 pm-12:41 am
1 stop10h 08m
$682
Santo DomingoSan Antonio
SDQ - SAT
SDQSAT
Santo Domingo Las Americas
Tue 8/11
7:00 am-11:25 pm
1 stop17h 25m
San Antonio
Mon 8/31
5:06 am-8:30 pm
1 stop14h 24m
$701
Santo DomingoSan Antonio
SDQ - SAT
SDQSAT
Santo Domingo Las Americas
Tue 8/11
10:25 am-11:25 pm
1 stop14h 00m
San Antonio
Sat 8/15
5:00 am-6:20 pm
2 stops12h 20m
$703
Santo DomingoSan Antonio
SDQ - SAT
SDQSAT
Santo Domingo Las Americas
Tue 8/11
3:20 pm-12:11 pm
2 stops21h 51m
San Antonio
Mon 8/31
5:30 am-10:46 pm
2 stops16h 16m
$759
Santo DomingoSan Antonio
SDQ - SAT
SDQSAT
Santo Domingo Las Americas
Wed 7/1
10:25 am-11:59 pm
1 stop14h 34m
San Antonio
Thu 7/9
8:00 am-10:59 pm
2 stops13h 59m
$825
Santo DomingoSan Antonio
SDQ - SAT
SDQSAT
Santo Domingo Las Americas
Tue 8/11
12:45 pm-9:05 am
2 stops21h 20m
San Antonio
Sat 8/15
11:15 am-11:50 am
3 stops23h 35m
$885
Santo DomingoSan Antonio
SDQ - SAT
SDQSAT
Santo Domingo Las Americas
Wed 7/1
12:45 pm-9:05 am
2 stops21h 20m
San Antonio
Thu 7/9
4:05 pm-5:59 am
2 stops12h 54m
$893
Cheapest one-way
Quickest one-way
Santo DomingoSan Antonio
SDQ - SAT
SDQSAT
Santo Domingo Las Americas
Sat 4/4
2:52 am-9:27 am
1 stop7h 35m
$324
Santo DomingoSan Antonio
SDQ - SAT
SDQSAT
Santo Domingo Las Americas
Sat 4/4
2:52 am-12:19 am
3 stops46h 27m
$341
Sorted by cheapest first
- Most accurate provider: When it comes to deals on Santo Domingo-San Antonio flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santo Domingo-San Antonio flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santo Domingo-San Antonio flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santo Domingo-San Antonio flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santo Domingo-San Antonio flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santo Domingo to San Antonio
Have a flexible travel schedule? Discover the best time to fly to San Antonio from Santo Domingo with our price prediction graph.
SDQ-SAT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santo Domingo to San Antonio
What is the cheapest month to book a flight from Santo Domingo to San Antonio?
Currently, June is the cheapest month in which you can book a flight from Santo Domingo to San Antonio (average of $172). Flying from Santo Domingo to San Antonio in April is currently the most expensive (average of $468). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Santo Domingo to San Antonio?
Reviews of airlines servicing San Antonio
Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated March 31, 2026.
Peruse reviews from past customers who have flown with American Airlines from Santo Domingo to San Antonio to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.5
Overall
7.1
Crew
7.9
Food
6.4
Comfort
7.2
Entertainment
6.9
Reviews
1 / 20
8.0
ExcellentMonica,Nov 2025
JAC - DFW
Boarding
7.5
Overall
7.1
Crew
7.9
Food
6.4
Comfort
7.2
Entertainment
6.9
Reviews
1 / 20
8.0
ExcellentMonica,Nov 2025
JAC - DFW
Related info for your journey
Find useful and relevant information for your journey from Santo Domingo to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Antonio?
Book flights to San Antonio if you plan to visit one of these locationsNew Braunfels
Kerrville
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Complete your trip
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Santo Domingo and San Antonio flights
Browse other Santo Domingo and San Antonio flight options. Last updated on March 31, 2026.
Other flights from Santo Domingo
Browse through other flights departing from Santo Domingo. Flights are based on user searches made on Cheapflights and were last updated on March 31, 2026.
Popular flight searches
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Other flights to San Antonio
Explore flights to San Antonio departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on March 31, 2026.
Top airline flying from Santo Domingo to San Antonio
Discover the top airline that operate flights from Santo Domingo to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$461 | Average$531 | FlexibilityNo cancel fee | On-time71% |