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$342+ Cheap flights from Santo Domingo (SDQ) to San Antonio (SAT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/8. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — SAT
Jan 27 — Feb 31
Tue 1/27
Tue 2/3
1 adult, Economy
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Cheap flight deals from Santo Domingo to San Antonio

Best flights from Santo Domingo to San Antonio
Discover carefully curated flight deals from Santo Domingo to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 28, 2025.

This United Airlines deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/206:00 amSDQ - SAT
2 stops19h 13mUnited Airlines
Sat 1/247:00 amSAT - SDQ
2 stops14h 46mUnited Airlines
Deal found 12/25$556
This American Airlines deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/12:16 pmSDQ - SAT
1 stop10h 43mAmerican Airlines
Sun 4/55:00 amSAT - SDQ
1 stop16h 53mAmerican Airlines
Deal found 12/28$607

Find flight deals from Santo Domingo to San Antonio

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to San Antonio (SAT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$556
(United Airlines)

One-way from

$342
(Frontier)

Popular in

October

Cheapest in

June

Average price

$508
Provider with most accurate pricing for Santo Domingo Las Americas-San Antonio flight deals.
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Provider most trusted by Cheapflights users for Santo Domingo Las Americas-San Antonio flights.
Search Deals
From Santo Domingo Las Americas to San Antonio
Search Deals
One-way flight from Santo Domingo Las Americas to San Antonio
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($12 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Santo Domingo to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
Use the filters below to find and compare flights from Santo Domingo to San Antonio that are best for you.

Fly from

Santo Domingo

Fly to

San Antonio

Route

Depart

Return

Price

Santo DomingoSan Antonio

SDQ - SAT

SDQSAT

Santo Domingo Las Americas

Tue 1/20

6:00 am-11:13 pm

2 stops19h 13m

San Antonio

Sat 1/24

7:00 am-11:46 pm

2 stops14h 46m

$556

Santo DomingoSan Antonio

SDQ - SAT

SDQSAT

Santo Domingo Las Americas

Wed 4/1

2:16 pm-11:59 pm

1 stop10h 43m

San Antonio

Sun 4/5

5:00 am-10:53 pm

1 stop16h 53m

$607

Santo DomingoSan Antonio

SDQ - SAT

SDQSAT

Santo Domingo Las Americas

Thu 1/8

10:56 am-6:18 pm

1 stop9h 22m

$342

Santo DomingoSan Antonio

SDQ - SAT

SDQSAT

Santo Domingo Las Americas

Thu 1/8

4:27 pm-9:40 am

2 stops43h 13m

$366

Santo DomingoSan Antonio

SDQ - SAT

SDQSAT

Santo Domingo Las Americas

Thu 1/8

6:00 am-11:58 pm

2 stops19h 58m

$387

Santo DomingoSan Antonio

SDQ - SAT

SDQSAT

Santo Domingo Las Americas

Sun 1/4

2:50 am-11:35 am

1 stop10h 45m

$430

Santo DomingoSan Antonio

SDQ - SAT

SDQSAT

Santo Domingo Las Americas

Wed 1/7

6:00 am-10:58 pm

2 stops18h 58m

$454

Santo DomingoSan Antonio

SDQ - SAT

SDQSAT

Santo Domingo Las Americas

Tue 1/6

2:10 pm-11:26 pm

3 stops35h 16m

$465

Santo DomingoSan Antonio

SDQ - SAT

SDQSAT

Santo Domingo Las Americas

Tue 1/6

8:45 pm-11:35 am

1 stop16h 50m

$512

Santo DomingoSan Antonio

SDQ - SAT

SDQSAT

Santo Domingo Las Americas

Mon 1/5

2:53 pm-11:50 am

1 stop22h 57m

$514

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/28

Compare providers for flights from Santo Domingo to San Antonio

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santo Domingo to San Antonio in December.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santo Domingo-San Antonio flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Santo Domingo-San Antonio flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Santo Domingo-San Antonio flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santo Domingo-San Antonio flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santo Domingo-San Antonio flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santo Domingo to San Antonio

Have a flexible travel schedule? Discover the best time to fly to San Antonio from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to San Antonio

What is the cheapest month to book a flight from Santo Domingo to San Antonio?

Currently, June is the cheapest month in which you can book a flight from Santo Domingo to San Antonio (average of $172). Flying from Santo Domingo to San Antonio in March is currently the most expensive (average of $458). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing San Antonio

Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated December 28, 2025.
Peruse reviews from past customers who have flown with American Airlines from Santo Domingo to San Antonio to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,072 reviews

Entertainment

6.9

Overall

7.2

Food

6.5

Boarding

7.5

Crew

8.0

Comfort

7.2

Reviews

1 / 20
8.0
Excellent

Monica,Nov 2025

JAC - DFW

At least there was an option of entertainment on this flight.
American Airlines
7.2
Good
11,072 reviews
American Airlines
7.2
Good
11,072 reviews

Entertainment

6.9

Overall

7.2

Food

6.5

Boarding

7.5

Crew

8.0

Comfort

7.2

Reviews

1 / 20
8.0
Excellent

Monica,Nov 2025

JAC - DFW

At least there was an option of entertainment on this flight.

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santo Domingo to San Antonio?

    Departing from Santo Domingo to San Antonio will take you 10h 43m. Santo Domingo and San Antonio are separated by a distance of 1965 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Santo Domingo to San Antonio round-trip?

    Currently priced at $449, American Airlines will fly you from Santo Domingo to San Antonio and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. American Airlines is priced at 19% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Santo Domingo to San Antonio that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to San Antonio flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to San Antonio?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to San Antonio.

  • Can I find deals for business class flights from Santo Domingo to San Antonio?

    Yes. Cheapflights offers flight deals from Santo Domingo to San Antonio by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to San Antonio?

    Currently, June is the cheapest month in which you can book a flight from Santo Domingo to San Antonio (average of $172). Flying from Santo Domingo to San Antonio in March is currently the most expensive (average of $458). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Antonio?

Book flights to San Antonio if you plan to visit one of these locations
New Braunfels
Kerrville

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Top airline flying from Santo Domingo to San Antonio

Discover the top airline that operate flights from Santo Domingo to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$449Average$515FlexibilityNo cancel feeOn-time71%

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