$76+ Cheap flights from Missouri to San Antonio (SAT)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/23. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SAT
Apr 21 — Apr 281
Round-trip
1 adult, Economy
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Find cheap flights from Missouri to San Antonio with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to San Antonio
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Cheapest flights from Missouri to San AntonioExplore the most affordable flight options available from Missouri to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 22, 2026.
Explore the most affordable flight options available from Missouri to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 22, 2026.
This CheapOair deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:51 pm
STL
- SAT
1 stop25h 23m
Frontier
Sun 5/107:54 pm
SAT
- STL
1 stop23h 29m
Frontier
Deal found 3/21![Frontier logo]()
$151
This CheapOair deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:51 pm
STL
- SAT
1 stop25h 23m
Frontier
Sat 5/168:59 pm
SAT
- STL
1 stop14h 22m
Frontier
Deal found 3/21![Frontier logo]()
$171
This CheapOair deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/38:16 pm
STL
- SAT
1 stop28h 03m
Frontier
Sun 4/56:45 am
SAT
- STL
1 stop27h 03m
Frontier
Deal found 3/20![Frontier logo]()
$191
This CheapOair deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:51 pm
STL
- SAT
1 stop25h 23m
Frontier
Sat 5/168:59 pm
SAT
- STL
1 stop14h 22m
Frontier
Deal found 3/22![Frontier logo]()
$192
This CheapOair deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/302:15 pm
MCI
- SAT
1 stop24h 00m
Frontier
Mon 5/43:00 pm
SAT
- MCI
1 stop22h 49m
Frontier
Deal found 3/18![Frontier logo]()
$212
This CheapOair deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:51 pm
STL
- SAT
1 stop25h 23m
Frontier
Fri 5/157:54 pm
SAT
- STL
1 stop23h 29m
Frontier
Deal found 3/21![Frontier logo]()
$212
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:23 pm
STL
- SAT
2 stops37h 01m
Frontier
Wed 4/224:49 pm
SAT
- STL
1 stop26h 32m
Frontier
Deal found 3/18![Frontier logo]()
$221
This CheapOair deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/12:15 pm
MCI
- SAT
1 stop24h 54m
Frontier
Wed 5/67:54 pm
SAT
- MCI
1 stop17h 55m
Frontier
Deal found 3/22![Frontier logo]()
$233
This CheapOair deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/174:59 pm
STL
- SAT
1 stop24h 36m
Frontier
Mon 4/201:51 pm
SAT
- STL
1 stop9h 28m
Frontier
Deal found 3/22![Frontier logo]()
$236
This Expedia deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/268:40 pm
MCI
- SAT
1 stop12h 26m
Frontier
Sun 3/296:45 am
SAT
- MCI
1 stop13h 10m
Frontier
Deal found 3/20![Frontier logo]()
$240
This CheapOair deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:45 am
MCI
- SAT
1 stop6h 42m
Multiple Airlines
Fri 4/173:00 pm
SAT
- MCI
1 stop23h 06m
Multiple Airlines
Deal found 3/18![Multiple Airlines logo]()
$245
This CheapOair deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/68:43 pm
MCI
- SAT
1 stop27h 36m
Frontier
Thu 4/96:45 am
SAT
- MCI
1 stop13h 16m
Frontier
Deal found 3/20![Frontier logo]()
$246
Best flights from Missouri to San AntonioDiscover carefully curated flight deals from Missouri to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 22, 2026.
Discover carefully curated flight deals from Missouri to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 22, 2026.
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/299:32 am
MCI
- SAT
1 stop7h 45m
Delta
Wed 5/612:26 pm
SAT
- MCI
1 stop7h 44m
Delta
Deal found 3/18![Delta logo]()
$275
This Southwest deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/291:25 pm
STL
- SAT
1 stop3h 55m
Southwest
Mon 5/47:20 am
SAT
- STL
Nonstop2h 10m
Southwest
Deal found 3/17![Southwest logo]()
$290
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:00 am
MCI
- SAT
2 stops7h 08m
United Airlines
Wed 4/227:40 am
SAT
- MCI
1 stop4h 19m
United Airlines
Deal found 3/19![United Airlines logo]()
$298
This American Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/37:46 pm
SGF
- SAT
1 stop4h 13m
American Airlines
Sun 4/57:00 am
SAT
- SGF
1 stop4h 35m
American Airlines
Deal found 3/21![American Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/149:24 am
STL
- SAT
1 stop8h 05m
Delta
Tue 7/217:50 am
SAT
- STL
1 stop6h 45m
Delta
Deal found 3/21![Delta logo]()
$291
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/188:45 am
STL
- SAT
Nonstop2h 15m
Southwest
Sat 4/257:15 am
SAT
- STL
1 stop6h 45m
Southwest
Deal found 3/18![Southwest logo]()
$294
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/149:10 am
STL
- SAT
2 stops8h 33m
United Airlines
Sat 4/1811:46 am
SAT
- STL
1 stop4h 22m
United Airlines
Deal found 3/17![United Airlines logo]()
$309
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/308:05 pm
MCI
- SAT
1 stop3h 25m
Southwest
Mon 5/412:55 pm
SAT
- MCI
Nonstop1h 55m
Southwest
Deal found 3/18![Southwest logo]()
$309
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:58 pm
SGF
- SAT
1 stop5h 26m
Delta
Sun 8/912:04 pm
SAT
- SGF
1 stop6h 09m
Delta
Deal found 3/22![Delta logo]()
$309
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:15 am
SGF
- SAT
1 stop4h 35m
United Airlines
Sat 4/411:46 am
SAT
- SGF
1 stop4h 41m
United Airlines
Deal found 3/18![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:49 pm
SGF
- SAT
1 stop5h 55m
Delta
Tue 6/95:30 pm
SAT
- SGF
1 stop5h 05m
Delta
Deal found 3/18![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/610:16 am
COU
- SAT
1 stop7h 28m
American Airlines
Sat 5/94:28 pm
SAT
- COU
1 stop6h 25m
American Airlines
Deal found 3/19![American Airlines logo]()
$390
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:10 am
STL
- SAT
2 stops10h 50m
Southwest
Mon 4/205:45 pm
SAT
- STL
1 stop5h 55m
Southwest
Deal found 3/22![Southwest logo]()
$326
This United Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/36:15 am
SGF
- SAT
1 stop4h 35m
United Airlines
Sun 4/59:40 am
SAT
- SGF
1 stop4h 37m
United Airlines
Deal found 3/20![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:55 pm
SGF
- SAT
1 stop5h 51m
Delta
Sat 4/255:20 am
SAT
- SGF
1 stop5h 41m
Delta
Deal found 3/19![Delta logo]()
$309
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/31:33 pm
SGF
- SAT
2 stops9h 26m
United Airlines
Tue 4/76:02 pm
SAT
- SGF
1 stop3h 58m
United Airlines
Deal found 3/19![United Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/77:03 am
STL
- SAT
1 stop5h 39m
Delta
Fri 4/101:37 pm
SAT
- STL
1 stop7h 29m
Delta
Deal found 3/17![Delta logo]()
$317
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/233:15 pm
MCI
- SAT
1 stop5h 45m
Southwest
Thu 5/2812:55 pm
SAT
- MCI
Nonstop1h 55m
Southwest
Deal found 3/19![Southwest logo]()
$362
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/71:33 pm
SGF
- SAT
2 stops9h 26m
United Airlines
Sat 4/114:17 pm
SAT
- SGF
1 stop4h 23m
United Airlines
Deal found 3/22![United Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:38 pm
MCI
- SAT
1 stop6h 06m
Delta
Mon 5/255:25 am
SAT
- MCI
1 stop5h 51m
Delta
Deal found 3/22![Delta logo]()
$327
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/38:30 am
STL
- SAT
Nonstop2h 20m
Southwest
Sun 5/106:55 pm
SAT
- STL
1 stop3h 55m
Southwest
Deal found 3/18![Southwest logo]()
$374
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:00 am
STL
- SAT
1 stop4h 50m
United Airlines
Sun 4/194:17 pm
SAT
- STL
1 stop6h 11m
United Airlines
Deal found 3/17![United Airlines logo]()
$356
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:41 pm
MCI
- SAT
1 stop5h 57m
Delta
Wed 4/812:24 pm
SAT
- MCI
1 stop7h 32m
Delta
Deal found 3/21![Delta logo]()
$335
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/296:41 pm
MCI
- SAT
1 stop5h 57m
Delta
Fri 4/246:12 pm
SAT
- MCI
1 stop4h 49m
Delta
Deal found 3/19![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/88:00 am
COU
- SAT
2 stops11h 48m
United Airlines
Sat 4/119:40 am
SAT
- COU
2 stops11h 23m
United Airlines
Deal found 3/18![United Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/11:25 pm
MCI
- SAT
1 stop7h 05m
Delta
Sun 4/55:10 am
SAT
- MCI
1 stop7h 17m
Delta
Deal found 3/20![Delta logo]()
$343
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/711:15 am
STL
- SAT
2 stops8h 33m
United Airlines
Fri 4/104:17 pm
SAT
- STL
1 stop6h 10m
United Airlines
Deal found 3/18![United Airlines logo]()
$403
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/221:54 pm
JLN
- SAT
1 stop6h 51m
United Airlines
Wed 8/264:13 pm
SAT
- JLN
2 stops7h 40m
United Airlines
Deal found 3/17![United Airlines logo]()
$404
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/29:23 am
STL
- SAT
1 stop6h 40m
United Airlines
Sun 7/55:30 am
SAT
- STL
2 stops10h 16m
United Airlines
Deal found 3/18![United Airlines logo]()
$406
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/49:02 am
COU
- SAT
2 stops8h 41m
United Airlines
Tue 4/76:49 am
SAT
- COU
1 stop7h 59m
United Airlines
Deal found 3/21![United Airlines logo]()
$414
Last-minute flights from Missouri to San AntonioDiscover last-minute flight deals from Missouri to San Antonio. Data last updated March 22, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to San Antonio. Data last updated March 22, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/218:12 pm
STL
- SAT
1 stop12h 54m
Frontier
Thu 3/266:45 am
SAT
- STL
1 stop27h 04m
Frontier
Deal found 3/20![Frontier logo]()
$261
This Expedia deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/268:40 pm
MCI
- SAT
1 stop12h 26m
Frontier
Sun 3/296:45 am
SAT
- MCI
1 stop13h 10m
Frontier
Deal found 3/20![Frontier logo]()
$240
This CheapOair deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/288:40 pm
MCI
- SAT
1 stop27h 37m
Frontier
Fri 4/36:45 am
SAT
- MCI
1 stop13h 13m
Frontier
Deal found 3/20![Frontier logo]()
$251
This Expedia deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/210:12 pm
STL
- SAT
1 stop12h 31m
Frontier
Sun 4/56:45 am
SAT
- STL
1 stop27h 03m
Frontier
Deal found 3/19![Frontier logo]()
$250
This CheapOair deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/38:16 pm
STL
- SAT
1 stop28h 03m
Frontier
Sun 4/56:45 am
SAT
- STL
1 stop27h 03m
Frontier
Deal found 3/20![Frontier logo]()
$191
This CheapOair deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/68:43 pm
MCI
- SAT
1 stop27h 36m
Frontier
Thu 4/96:45 am
SAT
- MCI
1 stop13h 16m
Frontier
Deal found 3/20![Frontier logo]()
$246
This CheapOair deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/91:14 pm
STL
- SAT
1 stop21h 29m
Frontier
Sun 4/126:45 am
SAT
- STL
1 stop27h 03m
Frontier
Deal found 3/20![Frontier logo]()
$257
This CheapOair deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:45 am
MCI
- SAT
1 stop6h 42m
Multiple Airlines
Fri 4/173:00 pm
SAT
- MCI
1 stop23h 06m
Multiple Airlines
Deal found 3/18![Multiple Airlines logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:23 pm
STL
- SAT
2 stops37h 01m
Frontier
Wed 4/224:49 pm
SAT
- STL
1 stop26h 32m
Frontier
Deal found 3/18![Frontier logo]()
$221
This CheapOair deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/174:59 pm
STL
- SAT
1 stop24h 36m
Frontier
Mon 4/201:51 pm
SAT
- STL
1 stop9h 28m
Frontier
Deal found 3/22![Frontier logo]()
$236
This CheapOair deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/302:15 pm
MCI
- SAT
1 stop24h 00m
Frontier
Mon 5/43:00 pm
SAT
- MCI
1 stop22h 49m
Frontier
Deal found 3/18![Frontier logo]()
$212
This CheapOair deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/302:15 pm
MCI
- SAT
1 stop24h 00m
Frontier
Sun 5/32:59 pm
SAT
- MCI
1 stop22h 31m
Frontier
Deal found 3/20![Frontier logo]()
$257
One-way flights from Missouri to San AntonioSearch for one-way flight options from Missouri to San Antonio. Find affordable one-way fares based on user searches. Data last updated March 22, 2026.
Search for one-way flight options from Missouri to San Antonio. Find affordable one-way fares based on user searches. Data last updated March 22, 2026.
This Frontier deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/239:55 pm
STL
- SAT
1 stop13h 45m
Frontier
Deal found 3/21![Frontier logo]()
$76
This CheapOair deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:08 pm
STL
- SAT
1 stop22h 51m
Frontier
Deal found 3/22![Frontier logo]()
$82
This Trip.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:06 pm
STL
- SAT
1 stop19h 03m
Frontier
Deal found 3/18![Frontier logo]()
$88
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/208:17 pm
STL
- SAT
1 stop18h 52m
Frontier
Deal found 3/18![Frontier logo]()
$100
This CheapOair deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/172:15 pm
MCI
- SAT
1 stop24h 54m
Frontier
Deal found 3/18![Frontier logo]()
$102
This CheapOair deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/91:14 pm
STL
- SAT
1 stop21h 29m
Frontier
Deal found 3/19![Frontier logo]()
$102
This Frontier deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1412:16 pm
STL
- SAT
1 stop7h 58m
Frontier
Deal found 3/18![Frontier logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/192:34 pm
MCI
- SAT
1 stop28h 25m
Frontier
Deal found 3/18![Frontier logo]()
$112
This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/169:55 pm
STL
- SAT
1 stop13h 13m
Frontier
Deal found 3/20![Frontier logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:23 pm
STL
- SAT
2 stops37h 01m
Frontier
Deal found 3/18![Frontier logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/162:15 pm
MCI
- SAT
1 stop24h 00m
Frontier
Deal found 3/19![Frontier logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/152:34 pm
MCI
- SAT
1 stop28h 25m
Frontier
Deal found 3/18![Frontier logo]()
$128
Find flight deals from Missouri to San Antonio
Keep the following information in mind while searching for Missouri to San Antonio flight deals. Data was last updated March 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $151 (CheapOair) |
One-way from | $76 (Frontier) |
Popular in | November |
Cheapest in | May |
Average price | $349 |
Good round-trip deal | $325 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
Use the filters below to find and compare flights from Missouri to San Antonio that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Kansas CitySan Antonio
MCI - SAT
MCISAT
Kansas City
Wed 4/29
9:32 am-5:17 pm
1 stop7h 45m
San Antonio
Wed 5/6
12:26 pm-8:10 pm
1 stop7h 44m
$275
St. LouisSan Antonio
STL - SAT
STLSAT
Lambert-St Louis
Wed 4/29
1:25 pm-5:20 pm
1 stop3h 55m
San Antonio
Mon 5/4
7:20 am-9:30 am
Nonstop2h 10m
$290
St. LouisSan Antonio
STL - SAT
STLSAT
Lambert-St Louis
Tue 7/14
9:24 am-5:29 pm
1 stop8h 05m
San Antonio
Tue 7/21
7:50 am-2:35 pm
1 stop6h 45m
$291
St. LouisSan Antonio
STL - SAT
STLSAT
Lambert-St Louis
Sat 4/18
8:45 am-11:00 am
Nonstop2h 15m
San Antonio
Sat 4/25
7:15 am-2:00 pm
1 stop6h 45m
$294
Kansas CitySan Antonio
MCI - SAT
MCISAT
Kansas City
Tue 4/21
6:00 am-1:08 pm
2 stops7h 08m
San Antonio
Wed 4/22
7:40 am-11:59 am
1 stop4h 19m
$298
St. LouisSan Antonio
STL - SAT
STLSAT
Lambert-St Louis
Tue 4/14
9:10 am-5:43 pm
2 stops8h 33m
San Antonio
Sat 4/18
11:46 am-4:08 pm
1 stop4h 22m
$309
Quickest round-trip
Kansas CitySan Antonio
MCI - SAT
MCISAT
Kansas City
Thu 4/30
8:05 pm-11:30 pm
1 stop3h 25m
San Antonio
Mon 5/4
12:55 pm-2:50 pm
Nonstop1h 55m
$309
SpringfieldSan Antonio
SGF - SAT
SGFSAT
Springfield-Branson
Thu 8/6
6:58 pm-12:24 am
1 stop5h 26m
San Antonio
Sun 8/9
12:04 pm-6:13 pm
1 stop6h 09m
$309
SpringfieldSan Antonio
SGF - SAT
SGFSAT
Springfield-Branson
Thu 6/4
6:49 pm-12:44 am
1 stop5h 55m
San Antonio
Tue 6/9
5:30 pm-10:35 pm
1 stop5h 05m
$309
SpringfieldSan Antonio
SGF - SAT
SGFSAT
Springfield-Branson
Mon 4/20
6:55 pm-12:46 am
1 stop5h 51m
San Antonio
Sat 4/25
5:20 am-11:01 am
1 stop5h 41m
$309
Showing 1-10 of 53 resultsSorted by cheapest first
Best time to book a flight from Missouri to San Antonio
Have a flexible travel schedule? Discover the best time to fly to San Antonio from Missouri with our price prediction graph.
STL-SAT
MCI-SAT
SGF-SAT
COU-SAT
JLN-SAT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to San Antonio
USMO-SAT
STL-SAT
MCI-SAT
SGF-SAT
COU-SAT
What is the cheapest month to book a flight from Missouri to San Antonio?
Currently, May is the cheapest month in which you can book a flight from Missouri to San Antonio (average of $119). Flying from Missouri to San Antonio in March is currently the most expensive (average of $236). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to SAT?
Find hourly flight availability from Missouri to San Antonio. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 22, 2026.
When flying from Missouri to San Antonio, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 38% versus a flight in the evening.
Related info for your journey
Find useful and relevant information for your journey from Missouri to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Antonio?
Book flights to San Antonio if you plan to visit one of these locationsNew Braunfels
Kerrville
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Missouri to San Antonio
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to San Antonio by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to San Antonio by cabin class
Find flights from Missouri to San Antonio, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and San Antonio flights
Browse other Missouri and San Antonio flight options. Last updated on March 22, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Antonio
Explore flights to San Antonio departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on March 22, 2026.
Missouri to San Antonio flights
Consider these flights traveling from Missouri to San Antonio.
Top 5 airlines flying from Missouri to San Antonio
Discover the top 5 airlines that operate flights from Missouri to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$111 | Average$288 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$151 | Average$186 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$192 | Average$307 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$198 | Average$373 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$216 | Average$372 | FlexibilityNo cancel fee | On-time63% |