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$64+ Cheap flights from Missouri to San Antonio (SAT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/8. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SAT
Jan 9 — Jan 161
Fri 1/9
Fri 1/16
1 adult, Economy
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Cheap flight deals from Missouri to San Antonio

Cheapest flights from Missouri to San Antonio
Explore the most affordable flight options available from Missouri to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 10, 2025.

This Booking.com deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:45 pmMCI - SAT
1 stop27h 32mFrontier
Fri 1/26:45 amSAT - MCI
1 stop13h 05mFrontier
Deal found 12/7$231
This Booking.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/248:45 pmMCI - SAT
1 stop16h 29mFrontier
Mon 12/296:45 amSAT - MCI
1 stop13h 05mFrontier
Deal found 12/9$246
This Delta deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:13 pmSTL - SAT
1 stop7h 06mDelta
Tue 1/65:20 amSAT - STL
1 stop5h 45mDelta
Deal found 12/9$259
This American Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/244:00 pmSGF - SAT
1 stop4h 41mAmerican Airlines
Mon 12/296:00 pmSAT - SGF
1 stop4h 25mAmerican Airlines
Deal found 12/8$264
This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:13 pmSTL - SAT
1 stop7h 06mDelta
Thu 1/15:10 amSAT - STL
1 stop7h 14mDelta
Deal found 12/10$269
This Booking.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/228:52 pmSTL - SAT
1 stop12h 31mFrontier
Wed 12/317:11 pmSAT - STL
1 stop27h 22mFrontier
Deal found 12/8$270
This Mytrip deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/207:43 pmSTL - SAT
1 stop15h 38mFrontier
Tue 12/232:01 pmSAT - STL
1 stop7h 24mFrontier
Deal found 12/9$279
This American Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/237:25 pmSGF - SAT
1 stop4h 26mAmerican Airlines
Sat 12/278:19 pmSAT - SGF
1 stop3h 37mAmerican Airlines
Deal found 12/8$279
This Kiwi.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3010:48 amSTL - SAT
2 stops31h 28mMultiple Airlines
Wed 1/712:45 pmSAT - STL
1 stop9h 48mMultiple Airlines
Deal found 12/9$291
This Kiwi.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3010:48 amSTL - SAT
2 stops31h 28mFrontier
Tue 1/63:55 pmSAT - STL
1 stop18h 07mFrontier
Deal found 12/9$302
This United Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/245:03 pmSGF - SAT
1 stop6h 44mUnited Airlines
Sat 12/275:59 pmSAT - SGF
1 stop4h 00mUnited Airlines
Deal found 12/9$303
This Booking.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/238:45 pmMCI - SAT
1 stop27h 32mMultiple Airlines
Sat 12/275:10 amSAT - MCI
1 stop9h 42mMultiple Airlines
Deal found 12/8$309

Find flight deals from Missouri to San Antonio

Keep the following information in mind while searching for Missouri to San Antonio flight deals. Data was last updated December 10, 2025.

Most accurate provider

Gotogate
3 stars

Most trusted provider

Gotogate
3 stars

Round-trip from

$140
(Booking.com)

One-way from

$64
(Super.com)

Popular in

November

Cheapest in

May

Average price

$383

Good round-trip deal

$414 or less
Provider with most accurate pricing for Lambert-St Louis-San Antonio flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-San Antonio flights.
Search Deals
From Missouri to San Antonio
Search Deals
One-way flight from Missouri to San Antonio
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($55 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from Missouri to San Antonio.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 10, 2025.
Use the filters below to find and compare flights from Missouri to San Antonio that are best for you.

Fly from

Missouri

Fly to

San Antonio

Route

Depart

Return

Price

St. LouisSan Antonio

STL - SAT

STLSAT

Lambert-St Louis

Wed 1/7

7:43 pm-9:18 am

1 stop13h 35m

San Antonio

Wed 1/14

6:30 am-10:34 pm

1 stop16h 04m

$184

St. LouisSan Antonio

STL - SAT

STLSAT

Lambert-St Louis

Fri 2/27

7:43 pm-9:18 am

1 stop13h 35m

San Antonio

Wed 3/4

4:13 pm-9:47 am

2 stops17h 34m

$211

Kansas CitySan Antonio

MCI - SAT

MCISAT

Kansas City

Fri 1/2

8:45 pm-12:36 pm

1 stop15h 51m

San Antonio

Mon 1/5

6:45 am-7:50 pm

1 stop13h 05m

$229

SpringfieldSan Antonio

SGF - SAT

SGFSAT

Springfield-Branson

Wed 1/7

5:00 pm-11:23 pm

1 stop6h 23m

San Antonio

Tue 1/13

11:12 am-4:15 pm

1 stop5h 03m

$249

SpringfieldSan Antonio

SGF - SAT

SGFSAT

Springfield-Branson

Sun 2/8

8:50 am-1:08 pm

1 stop4h 18m

San Antonio

Sat 2/14

11:43 am-4:25 pm

1 stop4h 42m

$249

SpringfieldSan Antonio

SGF - SAT

SGFSAT

Springfield-Branson

Tue 1/6

4:29 pm-10:58 pm

1 stop6h 29m

San Antonio

Tue 1/13

1:08 pm-7:13 pm

1 stop6h 05m

$249

SpringfieldSan Antonio

SGF - SAT

SGFSAT

Springfield-Branson

Tue 1/6

8:50 am-1:19 pm

1 stop4h 29m

San Antonio

Tue 1/13

11:43 am-4:27 pm

1 stop4h 44m

$249

SpringfieldSan Antonio

SGF - SAT

SGFSAT

Springfield-Branson

Tue 3/3

5:11 pm-10:28 pm

1 stop5h 17m

San Antonio

Tue 3/10

5:20 am-11:07 am

1 stop5h 47m

$249

SpringfieldSan Antonio

SGF - SAT

SGFSAT

Springfield-Branson

Thu 1/8

10:50 am-4:45 pm

1 stop5h 55m

San Antonio

Wed 1/14

1:08 pm-6:04 pm

1 stop4h 56m

$249

SpringfieldSan Antonio

SGF - SAT

SGFSAT

Springfield-Branson

Thu 1/8

10:50 am-3:45 pm

1 stop4h 55m

San Antonio

Mon 1/12

6:15 am-10:20 am

1 stop4h 05m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/9

Showing 1-10 of 50 results
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Best time to book a flight from Missouri to San Antonio

Have a flexible travel schedule? Discover the best time to fly to San Antonio from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to San Antonio

What is the cheapest month to book a flight from Missouri to San Antonio?

Currently, November is the cheapest month in which you can book a flight from Missouri to San Antonio (average of $144). Flying from Missouri to San Antonio in June is currently the most expensive (average of $210). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to SAT?

Find hourly flight availability from Missouri to San Antonio. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 10, 2025.

When flying from Missouri to San Antonio, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 33% versus a flight in the evening.

What is the cheapest day to fly from Missouri to San Antonio?

Use this chart to determine the cheapest time to fly round-trip from Missouri to San Antonio. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Missouri to San Antonio flight should consider departing on Tuesday evenings when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Missouri to San Antonio

Explore weekly flight availability from Missouri to San Antonio. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated December 10, 2025.

The most flights from USMO to SAT are scheduled on a Monday (3 on average). You will have fewer flight options on Friday, which is when the least amount of flights are scheduled (1 on average).

Related info for your journey

Find useful and relevant information for your journey from Missouri to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Antonio from Missouri?

    For a flight from Missouri to San Antonio, you will be flying into San Antonio. San Antonio (SAT) is just 7.6 mi from the center of the city.

  • How popular is this Missouri to San Antonio flight route?

    The Missouri to San Antonio flight path was viewed by 8 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Missouri to San Antonio?

    Airlines like Frontier, Delta, and United Airlines fly from Missouri to San Antonio in about 4h 18m. The time it takes to get you to your destination can typically vary by up to 9h 17m. Airlines will cover a distance of 608 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Missouri to San Antonio?

    While some choose either Lambert-St Louis - San Antonio or Springfield-Branson - San Antonio, Kansas City - San Antonio is the most popular route from Missouri to San Antonio.

  • What are the cheapest flights from Missouri to San Antonio?

    While on average a flight from Missouri to San Antonio is generally $470, our data shows the cheapest flight currently is $335. When looking at the most popular route, (Kansas City - San Antonio), you can expect to pay $219 for that flight.

  • Can I find deals for flights from Missouri to San Antonio that include hotel bookings?

    Yes. In addition to deals on Missouri to San Antonio flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to San Antonio?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to San Antonio.

  • Can I find deals for business class flights from Missouri to San Antonio?

    Yes. Cheapflights offers flight deals from Missouri to San Antonio by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to San Antonio?

    Currently, November is the cheapest month in which you can book a flight from Missouri to San Antonio (average of $144). Flying from Missouri to San Antonio in June is currently the most expensive (average of $210). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Antonio?

Book flights to San Antonio if you plan to visit one of these locations
New Braunfels
Kerrville

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Top 5 airlines flying from Missouri to San Antonio

Discover the top 5 airlines that operate flights from Missouri to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 10, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$124Average$263FlexibilityNo cancel feeOn-timeN/A
FrontierCheapest$151Average$220FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$198Average$386FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$202Average$370FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$228Average$346FlexibilityNo cancel feeOn-time69%

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