How long is the flight from Panama City, Florida to Rome?

Airlines like Delta fly from Panama City, Florida to Rome in about 21h 45m. The time it takes to get you to your destination can typically vary by up to . There are 5228 mi between Panama City, Florida and Rome.

What is the cheapest airline to fly from Panama City, Florida to Rome round-trip?

Our cheapest airline available from Panama City, Florida to Rome is Delta. Our recent data shows that you can find tickets from as low as $690 on this airline.

In terms of precipitation, rainfall in Rome ranges from 0.6 - 4.4 inches per month. November is typically the wettest month, when rainfall can reach 4.4 in. June is typically the driest time to visit Rome when rainfall is around 0.6 in.

If weather is an important factor for your trip to Rome, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 46.4 F).

What is the cheapest time of day to fly from ECP to ROM?

When flying from Panama City, Florida to Rome, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Most accurate provider : When it comes to deals on Panama City, Florida-Rome flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Panama City, Florida-Rome flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Rome flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Panama City, Florida-Rome flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Rome flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

What airport do you fly from for flights from Panama City to Rome?

Located just 16.0 mi from the city center, Panama City NW Florida Beaches is the airport most travelers will use when flying to Rome from Panama City. Booking flights from NW Florida Beaches (ECP) to Rome should be relatively easy as there are 0 daily outbound flights to Rome from 1 airline.

Can I find deals for flights from Panama City to Rome that include hotel bookings?

Yes. In addition to deals on Panama City to Rome flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Panama City to Rome?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Rome.

Can I find deals for business class flights from Panama City to Rome?

Yes. Cheapflights offers flight deals from Panama City to Rome by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$531+ Cheap Flights from Panama City, FL to Rome

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Panama City to Rome with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Panama City to Rome

Cheapest

Best

Last-minute

One-way

Cheapest flights from Panama City to Rome
Explore the most affordable flight options available from Panama City to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2026.

Wed 12/91:38 pm -

1 stop11h 37m

Sun 12/1310:25 am -

1 stop14h 39m

Deal found 11/4

$736

Fri 12/49:05 am -

2 stops15h 40m

Tue 12/811:15 am -

2 stops31h 51m

Deal found 11/4

$745

Mon 12/1411:22 am -

1 stop13h 53m

Mon 12/281:30 pm -

1 stop26h 07m

Deal found 11/7

$1,029

Wed 12/91:58 pm -

1 stop34h 47m

Mon 12/149:45 am -

1 stop34h 32m

Deal found 11/5

$1,071

Thu 12/2410:45 am -

1 stop14h 30m

Thu 12/3110:10 am -

2 stops30h 26m

Deal found 11/5

$1,112

Best flights from Panama City to Rome
Discover carefully curated flight deals from Panama City to Rome that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 10, 2026.

Sun 2/76:00 am -

2 stops21h 45m

Tue 2/1612:55 pm -

2 stops26h 45m

Deal found 11/5

$697

Wed 12/99:05 am -

2 stops16h 25m

Mon 12/1411:15 am -

2 stops33h 02m

Deal found 11/5

$745

Sun 2/72:10 pm -

2 stops15h 30m

Tue 2/167:05 am -

3 stops21h 46m

Deal found 11/5

$763

Mon 2/2211:05 am -

2 stops16h 40m

Tue 3/26:10 am -

2 stops24h 12m

Deal found 11/7

$733

Mon 1/1111:03 am -

2 stops15h 17m

Mon 1/181:30 pm -

1 stop17h 05m

Deal found 11/6

$753

Wed 12/99:05 am -

2 stops16h 25m

Mon 12/149:45 am -

1 stop34h 32m

Deal found 11/5

$766

Mon 1/117:50 am -

2 stops18h 30m

Mon 1/181:30 pm -

1 stop17h 05m

Deal found 11/5

$761

Last-minute flights from Panama City to Rome
Discover last-minute flight deals from Panama City to Rome. Data last updated November 10, 2026 and is based on user searches.

Fri 12/49:05 am -

2 stops15h 40m

Tue 12/811:15 am -

2 stops31h 51m

Deal found 11/4

$745

Wed 12/91:38 pm -

1 stop11h 37m

Sun 12/1310:25 am -

1 stop14h 39m

Deal found 11/4

$736

Wed 12/96:00 am -

2 stops18h 45m

Mon 12/1410:00 am -

2 stops20h 17m

Deal found 11/5

$741

Wed 12/91:58 pm -

1 stop34h 47m

Mon 12/149:45 am -

1 stop34h 32m

Deal found 11/5

$1,071

Mon 12/1411:22 am -

1 stop13h 53m

Mon 12/281:30 pm -

1 stop26h 07m

Deal found 11/7

$1,029

Thu 12/2410:45 am -

1 stop14h 30m

Thu 12/3110:10 am -

2 stops30h 26m

Deal found 11/5

$1,112

Find flight deals from Panama City to Rome

Most accurate provider	Ovago 3 stars
Most trusted provider	Ovago 3 stars
Round-trip from	$678 (eDestinos)
One-way from	$531 (oojo)

Provider with most accurate pricing for Panama City NW Florida Beaches-Rome (ROM) flight deals.

Search Deals

Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-Rome (ROM) flights.

Search Deals

From Panama City NW Florida Beaches to Rome (ROM)

Search Deals

One-way flight from Panama City NW Florida Beaches to Rome (ROM)

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityRome

ECP Panama City NW Florida Beaches - FCO Rome Fiumicino

ECPFCO

Panama City NW Florida Beaches

Sat 12/12

1:58 pm-7:45 am

1 stop34h 47m

Rome Fiumicino

Wed 12/31

12:00 am-5:00 pm

Nonstop0h 00m

$531

Quickest round-trip

Panama CityRome

ECP Panama City NW Florida Beaches - FCO Rome Fiumicino

ECPFCO

Panama City NW Florida Beaches

Sun 12/13

11:22 am-8:15 am

1 stop13h 53m

Rome Fiumicino

Wed 12/31

12:00 am-5:00 pm

Nonstop0h 00m

$538

Panama CityRome

ECP Panama City NW Florida Beaches - FCO Rome Fiumicino

ECPFCO

Panama City NW Florida Beaches

Sun 12/13

9:05 am-8:30 am

2 stops16h 25m

Rome Fiumicino

Wed 12/31

12:00 am-5:00 pm

Nonstop0h 00m

$538

Panama CityRome

ECP Panama City NW Florida Beaches - FCO Rome Fiumicino

ECPFCO

Panama City NW Florida Beaches

Sun 2/7

6:00 am-10:45 am

2 stops21h 45m

Rome Fiumicino

Tue 2/16

12:55 pm-8:40 am

2 stops26h 45m

$697

Panama CityRome

ECP Panama City NW Florida Beaches - FCO Rome Fiumicino

ECPFCO

Panama City NW Florida Beaches

Mon 2/22

11:05 am-10:45 am

2 stops16h 40m

Rome Fiumicino

Tue 3/2

6:10 am-11:22 pm

2 stops24h 12m

$733

Panama CityRome

ECP Panama City NW Florida Beaches - FCO Rome Fiumicino

ECPFCO

Panama City NW Florida Beaches

Wed 12/9

9:05 am-8:30 am

2 stops16h 25m

Rome Fiumicino

Mon 12/14

11:15 am-1:17 pm

2 stops33h 02m

$745

Panama CityRome

ECP Panama City NW Florida Beaches - FCO Rome Fiumicino

ECPFCO

Panama City NW Florida Beaches

Mon 1/11

11:03 am-9:20 am

2 stops15h 17m

Rome Fiumicino

Mon 1/18

1:30 pm-11:35 pm

1 stop17h 05m

$753

Panama CityRome

ECP Panama City NW Florida Beaches - FCO Rome Fiumicino

ECPFCO

Panama City NW Florida Beaches

Mon 1/11

7:50 am-9:20 am

2 stops18h 30m

Rome Fiumicino

Mon 1/18

1:30 pm-11:35 pm

1 stop17h 05m

$761

Panama CityRome

ECP Panama City NW Florida Beaches - FCO Rome Fiumicino

ECPFCO

Panama City NW Florida Beaches

Sun 2/7

2:10 pm-12:40 pm

2 stops15h 30m

Rome Fiumicino

Tue 2/16

7:05 am-9:51 pm

3 stops21h 46m

$763

Panama CityRome

ECP Panama City NW Florida Beaches - FCO Rome Fiumicino

ECPFCO

Panama City NW Florida Beaches

Wed 12/9

9:05 am-8:30 am

2 stops16h 25m

Rome Fiumicino

Mon 12/14

9:45 am-1:17 pm

1 stop34h 32m

$766

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/8

Sorted by cheapest first

Compare providers for flights from Panama City to Rome

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Rome in November.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy1 star	Trust Score*3 stars
Ovago	Price Accuracy3 stars	Trust Score*3 stars
AranGrant	Price Accuracy3 stars	Trust Score*3 stars
eDreams	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Panama City, Florida-Rome flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Panama City, Florida-Rome flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Rome flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Panama City, Florida-Rome flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Rome flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Rome

Have a flexible travel schedule? Discover the best time to fly to Rome from Panama City with our price prediction graph.

ECP-ROM

ECP-FCO

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Rome

ECP-ROM

ECP-FCO

No data available for this route at this time. Please check back soon.

Related info for your journey

What airport do you fly from for flights from Panama City to Rome?
Located just 16.0 mi from the city center, Panama City NW Florida Beaches is the airport most travelers will use when flying to Rome from Panama City. Booking flights from NW Florida Beaches (ECP) to Rome should be relatively easy as there are 0 daily outbound flights to Rome from 1 airline.
How long is the flight from Panama City, Florida to Rome?
Airlines like Delta fly from Panama City, Florida to Rome in about 21h 45m. The time it takes to get you to your destination can typically vary by up to . There are 5228 mi between Panama City, Florida and Rome.
What is the cheapest airline to fly from Panama City, Florida to Rome round-trip?
Our cheapest airline available from Panama City, Florida to Rome is Delta. Our recent data shows that you can find tickets from as low as $690 on this airline.
Can I find deals for flights from Panama City to Rome that include hotel bookings?
Yes. In addition to deals on Panama City to Rome flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Panama City to Rome?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Rome.
Can I find deals for business class flights from Panama City to Rome?
Yes. Cheapflights offers flight deals from Panama City to Rome by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Fiumicino

Civitavecchia

Montepulciano

Santa Marinella

Browse thousands of different options on Cheapflights for your next trip

Alternative routes

Complete your trip

Flights by cabin class

Other flight options

Other flights from Panama City

Popular flights

Rome flight routes

Alternative routes for Panama City to Rome

Miami to Leonardo da Vinci/Fiumicino flights

Orlando to Leonardo da Vinci/Fiumicino flights

Tampa to Leonardo da Vinci/Fiumicino flights

Fort Myers to Leonardo da Vinci/Fiumicino flights

Orlando to Ciampino flights

Valparaiso to Leonardo da Vinci/Fiumicino flights

Melbourne to Leonardo da Vinci/Fiumicino flights

Top airline flying from Panama City to Rome

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$690	Average$1,539	FlexibilityNo cancel fee	On-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$531+ Cheap flights from Panama City, FL (ECP) to Rome (ROM)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/12. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Panama City to Rome with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Panama City to Rome

Cheapest flights from Panama City to RomeExplore the most affordable flight options available from Panama City to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2026.

Explore the most affordable flight options available from Panama City to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2026.

Best flights from Panama City to RomeDiscover carefully curated flight deals from Panama City to Rome that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 10, 2026.

Discover carefully curated flight deals from Panama City to Rome that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 10, 2026.

Last-minute flights from Panama City to RomeDiscover last-minute flight deals from Panama City to Rome. Data last updated November 10, 2026 and is based on user searches.

Discover last-minute flight deals from Panama City to Rome. Data last updated November 10, 2026 and is based on user searches.

One-way flights from Panama City to RomeSearch for one-way flight options from Panama City to Rome. Find affordable one-way fares based on user searches. Data last updated November 10, 2026.

Search for one-way flight options from Panama City to Rome. Find affordable one-way fares based on user searches. Data last updated November 10, 2026.

Find flight deals from Panama City to Rome

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Cheapflights Fare Finder

Use the filters below to find and compare flights from Panama City to Rome that are best for you.

Compare providers for flights from Panama City to Rome

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Rome in November.

Best time to book a flight from Panama City to Rome

Have a flexible travel schedule? Discover the best time to fly to Rome from Panama City with our price prediction graph.

Cheapflights Insights

Related info for your journey

What airport do you fly from for flights from Panama City to Rome?

How long is the flight from Panama City, Florida to Rome?

What is the cheapest airline to fly from Panama City, Florida to Rome round-trip?

Can I find deals for flights from Panama City to Rome that include hotel bookings?

How can I find direct flights from Panama City to Rome?

Can I find deals for business class flights from Panama City to Rome?

Traveling to a place near Rome?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama City to Rome

See prices for flight routes from nearby airports that may be better suited for you.

Complete your trip

Complete your trip to Rome by adding a car rental and/or hotel reservation to your travel itinerary.

Search flights from Panama City to Rome by cabin class

Find flights from Panama City to Rome, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Panama City and Rome flights

Browse other Panama City and Rome flight options. Last updated on November 10, 2026.

Other flights from Panama City

Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on November 10, 2026.

Popular flight searches

Check out other popular destinations found by fellow travelers in 2026

Other flights to Rome

Explore flights to Rome departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on November 10, 2026.

Top airline flying from Panama City to Rome

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Panama City to Rome
Explore the most affordable flight options available from Panama City to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2026.

Best flights from Panama City to Rome
Discover carefully curated flight deals from Panama City to Rome that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 10, 2026.

Last-minute flights from Panama City to Rome
Discover last-minute flight deals from Panama City to Rome. Data last updated November 10, 2026 and is based on user searches.

One-way flights from Panama City to Rome
Search for one-way flight options from Panama City to Rome. Find affordable one-way fares based on user searches. Data last updated November 10, 2026.