$356+ Cheap flights from Panama City, FL (ECP) to Rome (ROM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/30. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — ROM
Sep 21 — Sep 281
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to Rome with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to Rome
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Best
Last-minute
One-way
Cheapest flights from Panama City to RomeExplore the most affordable flight options available from Panama City to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 22, 2026.
Explore the most affordable flight options available from Panama City to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 22, 2026.
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/225:28 pm -
2 stops58h 27m
Mon 12/289:55 am -
2 stops37h 50m
Deal found 8/20![United Airlines logo]()
$902
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2411:15 am -
1 stop14h 00m
Thu 12/316:00 am -
2 stops23h 47m
Deal found 8/17![Delta logo]()
$910
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/246:23 am -
2 stops21h 32m
Thu 12/317:05 am -
2 stops21h 53m
Deal found 8/19![United Airlines logo]()
$944
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:20 am -
2 stops21h 35m
Wed 10/710:00 am -
2 stops19h 18m
Deal found 8/18![United Airlines logo]()
$972
This KLM deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:19 pm -
2 stops15h 16m
Wed 10/79:45 am -
1 stop17h 18m
Deal found 8/18![Multiple Airlines logo]()
$977
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:35 am -
1 stop17h 00m
Wed 10/71:10 pm -
1 stop17h 08m
Deal found 8/18![Delta logo]()
$980
This Air France deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2411:15 am -
1 stop14h 00m
Thu 12/3112:45 pm -
2 stops17h 02m
Deal found 8/21![Multiple Airlines logo]()
$984
This oojo deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/11:46 pm -
2 stops21h 49m
Thu 10/87:25 pm -
2 stops32h 41m
Deal found 8/17![Scandinavian Airlines logo]()
$1,038
Best flights from Panama City to RomeDiscover carefully curated flight deals from Panama City to Rome that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 22, 2026.
Discover carefully curated flight deals from Panama City to Rome that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 22, 2026.
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/156:30 am -
2 stops28h 15m
Fri 2/191:15 pm -
2 stops27h 22m
Deal found 8/17![United Airlines logo]()
$813
This KLM deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/113:30 pm -
1 stop12h 50m
Mon 1/1810:55 am -
2 stops18h 52m
Deal found 8/19![KLM logo]()
$823
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2411:15 am -
1 stop14h 00m
Thu 12/316:00 am -
2 stops23h 47m
Deal found 8/17![Delta logo]()
$910
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:35 am -
1 stop17h 00m
Wed 10/71:10 pm -
1 stop17h 08m
Deal found 8/18![Delta logo]()
$980
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:19 pm -
1 stop11h 21m
Sun 10/116:30 am -
2 stops21h 36m
Deal found 8/21![Delta logo]()
$1,040
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:19 pm -
2 stops17h 46m
Thu 10/89:45 am -
1 stop18h 21m
Deal found 8/17![Delta logo]()
$1,044
Last-minute flights from Panama City to RomeDiscover last-minute flight deals from Panama City to Rome. Data last updated August 22, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Rome. Data last updated August 22, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/39:27 am -
1 stop18h 23m
Thu 9/106:30 am -
2 stops23h 35m
Deal found 8/19![Delta logo]()
$1,144
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/32:27 pm -
2 stops34h 48m
Thu 9/1011:30 am -
2 stops32h 43m
Deal found 8/17![United Airlines logo]()
$1,285
This FlightHub deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/31:53 pm -
2 stops38h 12m
Thu 9/107:25 pm -
2 stops34h 40m
Deal found 8/18![Scandinavian Airlines logo]()
$1,326
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:30 am -
2 stops23h 45m
Thu 9/2410:00 am -
2 stops19h 18m
Deal found 8/17![United Airlines logo]()
$1,043
This Air France deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/174:33 pm -
2 stops14h 52m
Thu 9/249:45 am -
1 stop14h 49m
Deal found 8/17![Multiple Airlines logo]()
$1,044
This KLM deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1711:19 am -
1 stop13h 16m
Thu 9/249:45 am -
1 stop20h 40m
Deal found 8/17![KLM logo]()
$1,317
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:20 am -
2 stops21h 35m
Wed 10/710:00 am -
2 stops19h 18m
Deal found 8/18![United Airlines logo]()
$972
This KLM deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:19 pm -
2 stops15h 16m
Wed 10/79:45 am -
1 stop17h 18m
Deal found 8/18![Multiple Airlines logo]()
$977
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:35 am -
1 stop17h 00m
Wed 10/71:10 pm -
1 stop17h 08m
Deal found 8/18![Delta logo]()
$980
One-way flights from Panama City to RomeSearch for one-way flight options from Panama City to Rome. Find affordable one-way fares based on user searches. Data last updated August 22, 2026.
Search for one-way flight options from Panama City to Rome. Find affordable one-way fares based on user searches. Data last updated August 22, 2026.
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/301:34 pm -
1 stop14h 46m
Deal found 8/18![Delta logo]()
$356
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:00 am -
2 stops20h 35m
Deal found 8/20![Delta logo]()
$463
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/72:15 pm -
2 stops35h 40m
Deal found 8/20![United Airlines logo]()
$467
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:40 pm -
1 stop31h 35m
Deal found 8/20![Delta logo]()
$475
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/142:15 pm -
1 stop34h 30m
Deal found 8/20![United Airlines logo]()
$476
This British Airways deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/83:56 pm -
2 stops18h 54m
Deal found 8/20![Multiple Airlines logo]()
$496
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/121:34 pm -
1 stop14h 46m
Deal found 8/20![Delta logo]()
$513
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/62:35 pm -
1 stop13h 45m
Deal found 8/20![Delta logo]()
$523
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:30 am -
2 stops32h 30m
Deal found 8/18![United Airlines logo]()
$531
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/317:35 am -
2 stops20h 25m
Deal found 8/18![Delta logo]()
$575
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/307:35 am -
1 stop20h 15m
Deal found 8/18![Delta logo]()
$627
Find flight deals from Panama City to Rome
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Rome (ROM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 22, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $792 (United Airlines) |
One-way from | $356 (Delta) |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Rome that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 22, 2026.
Use the filters below to find and compare flights from Panama City to Rome that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityRome
ECP Panama City NW Florida Beaches - FCO Rome Fiumicino
ECPFCO
Panama City NW Florida Beaches
Mon 2/15
6:30 am-5:45 pm
2 stops28h 15m
Rome Fiumicino
Fri 2/19
1:15 pm-9:37 am
2 stops27h 22m
$813
Quickest round-trip
Panama CityRome
ECP Panama City NW Florida Beaches - FCO Rome Fiumicino
ECPFCO
Panama City NW Florida Beaches
Mon 1/11
3:30 pm-11:20 am
1 stop12h 50m
Rome Fiumicino
Mon 1/18
10:55 am-10:47 pm
2 stops18h 52m
$823
Panama CityRome
ECP Panama City NW Florida Beaches - FCO Rome Fiumicino
ECPFCO
Panama City NW Florida Beaches
Thu 12/24
11:15 am-8:15 am
1 stop14h 00m
Rome Fiumicino
Thu 12/31
6:00 am-10:47 pm
2 stops23h 47m
$910
Panama CityRome
ECP Panama City NW Florida Beaches - FCO Rome Fiumicino
ECPFCO
Panama City NW Florida Beaches
Mon 9/28
7:35 am-7:35 am
1 stop17h 00m
Rome Fiumicino
Wed 10/7
1:10 pm-11:18 pm
1 stop17h 08m
$980
Panama CityRome
ECP Panama City NW Florida Beaches - FCO Rome Fiumicino
ECPFCO
Panama City NW Florida Beaches
Sun 10/4
6:19 pm-12:40 pm
1 stop11h 21m
Rome Fiumicino
Sun 10/11
6:30 am-9:06 pm
2 stops21h 36m
$1,040
Panama CityRome
ECP Panama City NW Florida Beaches - FCO Rome Fiumicino
ECPFCO
Panama City NW Florida Beaches
Thu 10/1
6:19 pm-7:05 pm
2 stops17h 46m
Rome Fiumicino
Thu 10/8
9:45 am-9:06 pm
1 stop18h 21m
$1,044
Cheapest one-way
Panama CityRome
ECP Panama City NW Florida Beaches - FCO Rome Fiumicino
ECPFCO
Panama City NW Florida Beaches
Mon 11/30
1:34 pm-11:20 am
1 stop14h 46m
$356
Panama CityRome
ECP Panama City NW Florida Beaches - FCO Rome Fiumicino
ECPFCO
Panama City NW Florida Beaches
Wed 11/11
11:28 am-8:15 am
1 stop13h 47m
$463
Panama CityRome
ECP Panama City NW Florida Beaches - FCO Rome Fiumicino
ECPFCO
Panama City NW Florida Beaches
Tue 11/10
7:00 am-11:20 am
1 stop21h 20m
$463
Panama CityRome
ECP Panama City NW Florida Beaches - FCO Rome Fiumicino
ECPFCO
Panama City NW Florida Beaches
Sat 11/7
2:15 pm-8:55 am
2 stops35h 40m
$467
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from Panama City to Rome
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Rome in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City, Florida-Rome flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Panama City, Florida-Rome flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Rome flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City, Florida-Rome flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Rome flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to Rome
Have a flexible travel schedule? Discover the best time to fly to Rome from Panama City with our price prediction graph.
ECP-ROM
ECP-FCO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Rome
ECP-ROM
ECP-FCO
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Rome
Get insights into the airlines that provide service to Rome. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Rome. Reviews last updated August 22, 2026.
Get a feel of what it's like to fly with Delta from Panama City to Rome by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Overall
7.8
Entertainment
7.8
Crew
8.5
Comfort
7.8
Food
7.2
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Boarding
8.1
Overall
7.8
Entertainment
7.8
Crew
8.5
Comfort
7.8
Food
7.2
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Related info for your journey
Find useful and relevant information for your journey from Panama City to Rome. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Rome?
Book flights to Rome if you plan to visit one of these locationsFiumicino
Civitavecchia
Montepulciano
Santa Marinella
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Panama City and Rome flights
Browse other Panama City and Rome flight options. Last updated on August 22, 2026.
Other flights from Panama City
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Popular flight searches
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Explore flights to Rome departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 22, 2026.
Top airline flying from Panama City to Rome
Discover the top airline that operate flights from Panama City to Rome. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$729 | Average$1,539 | FlexibilityNo cancel fee | On-timeN/A |