$734+ Cheap flights from Panama City, FL (ECP) to Rome (ROM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/11. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — ROM
Oct 5 — Oct 121
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to Rome with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to Rome
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Cheapest flights from Panama City to RomeExplore the most affordable flight options available from Panama City to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 5, 2026.
Explore the most affordable flight options available from Panama City to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 5, 2026.
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/124:57 pm -
2 stops46h 03m
Tue 10/206:50 am -
2 stops22h 28m
Deal found 9/1![United Airlines logo]()
$861
This Air France deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/241:59 pm -
1 stop14h 21m
Thu 12/3112:30 pm -
2 stops16h 02m
Deal found 9/4![Air France logo]()
$883
This Delta deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/248:02 am -
2 stops19h 43m
Thu 12/316:00 am -
2 stops22h 32m
Deal found 9/4![Delta logo]()
$888
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1511:21 am -
1 stop13h 14m
Thu 10/226:30 am -
2 stops21h 36m
Deal found 8/31![Delta logo]()
$904
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:20 am -
2 stops19h 55m
Thu 10/2210:00 am -
2 stops19h 18m
Deal found 8/31![United Airlines logo]()
$907
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:42 pm -
2 stops17h 38m
Sat 10/3111:00 am -
2 stops30h 42m
Deal found 9/1![American Airlines logo]()
$910
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:20 pm -
1 stop11h 20m
Sat 10/311:30 pm -
1 stop15h 48m
Deal found 9/1![Delta logo]()
$932
This KLM deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/189:19 am -
1 stop15h 16m
Sun 10/2512:50 pm -
2 stops16h 28m
Deal found 9/3![KLM logo]()
$1,051
Best flights from Panama City to RomeDiscover carefully curated flight deals from Panama City to Rome that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 5, 2026.
Discover carefully curated flight deals from Panama City to Rome that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 5, 2026.
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/112:08 pm -
2 stops34h 47m
Mon 1/182:10 pm -
2 stops54h 07m
Deal found 9/4![United Airlines logo]()
$734
This KLM deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/1112:00 pm -
1 stop16h 20m
Mon 1/186:10 am -
2 stops20h 26m
Deal found 9/1![KLM logo]()
$773
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1511:21 am -
1 stop13h 14m
Thu 10/226:30 am -
2 stops21h 36m
Deal found 8/31![Delta logo]()
$904
This KLM deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/141:30 pm -
1 stop14h 50m
Sun 2/216:10 am -
2 stops18h 40m
Deal found 9/2![KLM logo]()
$782
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2610:25 am -
1 stop14h 20m
Tue 3/99:45 am -
1 stop30h 52m
Deal found 9/1![United Airlines logo]()
$820
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:12 am -
1 stop22h 28m
Sat 10/3110:10 am -
2 stops29h 04m
Deal found 9/1![Delta logo]()
$932
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/244:06 pm -
1 stop12h 14m
Thu 12/3110:10 am -
2 stops30h 33m
Deal found 9/3![Delta logo]()
$950
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/174:55 pm -
2 stops35h 00m
Fri 11/207:05 am -
2 stops21h 31m
Deal found 9/4![United Airlines logo]()
$1,104
Last-minute flights from Panama City to RomeDiscover last-minute flight deals from Panama City to Rome. Data last updated September 5, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Rome. Data last updated September 5, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:00 am -
1 stop18h 35m
Tue 10/69:45 am -
1 stop17h 18m
Deal found 9/3![Delta logo]()
$1,084
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:20 am -
2 stops19h 55m
Tue 10/66:50 am -
2 stops22h 28m
Deal found 9/3![United Airlines logo]()
$1,087
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/411:41 am -
2 stops18h 34m
Sat 10/1010:50 am -
2 stops42h 28m
Deal found 9/3![United Airlines logo]()
$1,213
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/124:57 pm -
2 stops46h 03m
Tue 10/206:50 am -
2 stops22h 28m
Deal found 9/1![United Airlines logo]()
$861
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:42 pm -
2 stops17h 38m
Sat 10/3111:00 am -
2 stops30h 42m
Deal found 9/1![American Airlines logo]()
$910
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:12 am -
1 stop22h 28m
Sat 10/3110:10 am -
2 stops29h 04m
Deal found 9/1![Delta logo]()
$932
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1511:21 am -
1 stop13h 14m
Thu 10/226:30 am -
2 stops21h 36m
Deal found 8/31![Delta logo]()
$904
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:20 am -
2 stops19h 55m
Thu 10/2210:00 am -
2 stops19h 18m
Deal found 8/31![United Airlines logo]()
$907
This KLM deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/189:19 am -
1 stop15h 16m
Sun 10/2512:50 pm -
2 stops16h 28m
Deal found 9/3![KLM logo]()
$1,051
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/181:35 pm -
2 stops14h 50m
Sun 10/256:10 am -
2 stops23h 08m
Deal found 9/3![Delta logo]()
$1,056
Find flight deals from Panama City to Rome
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Rome (ROM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 5, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $734 (United Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Rome that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 5, 2026.
Use the filters below to find and compare flights from Panama City to Rome that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityRome
ECP Panama City NW Florida Beaches - FCO Rome Fiumicino
ECPFCO
Panama City NW Florida Beaches
Mon 1/11
2:08 pm-7:55 am
2 stops34h 47m
Rome Fiumicino
Mon 1/18
2:10 pm-1:17 pm
2 stops54h 07m
$734
Panama CityRome
ECP Panama City NW Florida Beaches - FCO Rome Fiumicino
ECPFCO
Panama City NW Florida Beaches
Mon 1/11
12:00 pm-11:20 am
1 stop16h 20m
Rome Fiumicino
Mon 1/18
6:10 am-7:36 pm
2 stops20h 26m
$773
Quickest round-trip
Panama CityRome
ECP Panama City NW Florida Beaches - FCO Rome Fiumicino
ECPFCO
Panama City NW Florida Beaches
Sun 2/14
1:30 pm-11:20 am
1 stop14h 50m
Rome Fiumicino
Sun 2/21
6:10 am-5:50 pm
2 stops18h 40m
$782
Panama CityRome
ECP Panama City NW Florida Beaches - FCO Rome Fiumicino
ECPFCO
Panama City NW Florida Beaches
Fri 2/26
10:25 am-7:45 am
1 stop14h 20m
Rome Fiumicino
Tue 3/9
9:45 am-9:37 am
1 stop30h 52m
$820
Panama CityRome
ECP Panama City NW Florida Beaches - FCO Rome Fiumicino
ECPFCO
Panama City NW Florida Beaches
Thu 10/15
11:21 am-7:35 am
1 stop13h 14m
Rome Fiumicino
Thu 10/22
6:30 am-9:06 pm
2 stops21h 36m
$904
Panama CityRome
ECP Panama City NW Florida Beaches - FCO Rome Fiumicino
ECPFCO
Panama City NW Florida Beaches
Wed 10/14
7:12 am-12:40 pm
1 stop22h 28m
Rome Fiumicino
Sat 10/31
10:10 am-9:14 am
2 stops29h 04m
$932
Panama CityRome
ECP Panama City NW Florida Beaches - FCO Rome Fiumicino
ECPFCO
Panama City NW Florida Beaches
Thu 12/24
4:06 pm-11:20 am
1 stop12h 14m
Rome Fiumicino
Thu 12/31
10:10 am-9:43 am
2 stops30h 33m
$950
Panama CityRome
ECP Panama City NW Florida Beaches - FCO Rome Fiumicino
ECPFCO
Panama City NW Florida Beaches
Tue 11/17
4:55 pm-10:55 am
2 stops35h 00m
Rome Fiumicino
Fri 11/20
7:05 am-9:36 pm
2 stops21h 31m
$1,104
Sorted by cheapest first
Compare providers for flights from Panama City to Rome
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Rome in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City, Florida-Rome flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Panama City, Florida-Rome flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Rome flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City, Florida-Rome flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Rome flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to Rome
Have a flexible travel schedule? Discover the best time to fly to Rome from Panama City with our price prediction graph.
ECP-ROM
ECP-FCO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Rome
ECP-ROM
ECP-FCO
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Rome
Get insights into the airlines that provide service to Rome. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Rome. Reviews last updated September 5, 2026.
Get a feel of what it's like to fly with Delta from Panama City to Rome by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Overall
7.8
Food
7.2
Comfort
7.8
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Boarding
8.1
Overall
7.8
Food
7.2
Comfort
7.8
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from Panama City to Rome. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Rome?
Book flights to Rome if you plan to visit one of these locationsFiumicino
Civitavecchia
Montepulciano
Santa Marinella
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Complete your trip
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Panama City and Rome flights
Browse other Panama City and Rome flight options. Last updated on September 5, 2026.
Other flights from Panama City
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Popular flight searches
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Explore flights to Rome departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 5, 2026.
Top airline flying from Panama City to Rome
Discover the top airline that operate flights from Panama City to Rome. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$823 | Average$1,539 | FlexibilityNo cancel fee | On-timeN/A |