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$483+ Cheap flights from Panama City, FL (ECP) to Rome (ROM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/15. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — ROM
Dec 23 — Dec 301
Tue 12/23
Tue 12/30
1 adult, Economy
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Cheap flight deals from Panama City to Rome

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Rome (ROM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 23, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$494
(United Airlines)

One-way from

$483
(KLM)

Popular in

May

Cheapest in

January

Average price

$797
Provider with most accurate pricing for Panama City NW Florida Beaches-Rome (ROM) flight deals.
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Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-Rome (ROM) flights.
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From Panama City NW Florida Beaches to Rome (ROM)
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One-way flight from Panama City NW Florida Beaches to Rome (ROM)
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Highest demand for flights based on searches. 28% potential increase in price ($445 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($80 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Panama City to Rome

Cheapest flights from Panama City to Rome
Explore the most affordable flight options available from Panama City to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 23, 2025.

This United Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/176:30 amECP - FCO
2 stops18h 15mUnited Airlines
Wed 12/247:05 amFCO - ECP
2 stops37h 22mUnited Airlines
Deal found 11/23$1,197
This KLM deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/171:32 pmECP - FCO
1 stop13h 58mKLM
Wed 12/2410:05 amFCO - ECP
1 stop19h 57mKLM
Deal found 11/23$1,480
This Delta deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/177:30 amECP - FCO
1 stop17h 25mDelta
Wed 12/2410:05 amFCO - ECP
2 stops19h 57mDelta
Deal found 11/23$1,484
This United Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/224:45 pmECP - FCO
2 stops56h 45mUnited Airlines
Mon 12/2910:55 amFCO - ECP
2 stops57h 32mUnited Airlines
Deal found 11/23$1,660
This KLM deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/227:02 pmECP - FCO
1 stop29h 53mKLM
Mon 12/2912:40 pmFCO - ECP
1 stop14h 16mKLM
Deal found 11/23$1,877
This Delta deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/229:22 amECP - FCO
2 stops16h 48mDelta
Mon 12/2912:40 pmFCO - ECP
1 stop14h 16mDelta
Deal found 11/23$2,524

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Rome that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 23, 2025.
Use the filters below to find and compare flights from Panama City to Rome that are best for you.

Fly from

Panama City

Fly to

Rome

Route

Depart

Return

Price

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Wed 1/21

6:30 am-7:55 am

2 stops18h 25m

Rome Fiumicino

Sun 1/25

12:45 pm-12:02 pm

2 stops30h 17m

$494

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Wed 1/21

12:15 pm-10:30 am

1 stop15h 15m

Rome Fiumicino

Sun 1/25

12:45 pm-10:40 pm

2 stops16h 55m

$506

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Tue 1/6

6:00 am-9:45 am

2 stops20h 45m

Rome Fiumicino

Tue 1/13

12:00 pm-10:51 pm

2 stops17h 51m

$920

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Tue 1/6

5:14 pm-10:30 am

1 stop34h 16m

Rome Fiumicino

Tue 1/13

12:00 pm-10:51 pm

2 stops17h 51m

$988

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Sun 3/15

8:05 am-6:55 am

1 stop16h 50m

$483

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Sun 3/15

11:00 am-8:45 am

2 stops15h 45m

$483

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Sun 3/15

5:03 pm-10:05 am

3 stops35h 02m

$3,551

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/23

Compare providers for flights from Panama City to Rome

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Rome in November.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City, Florida-Rome flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Panama City, Florida-Rome flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Rome flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City, Florida-Rome flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Rome flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Rome

Have a flexible travel schedule? Discover the best time to fly to Rome from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Rome

What is the cheapest month to book a flight from Panama City, Florida to Rome?

Currently, October is the cheapest month in which you can book a flight from Panama City, Florida to Rome (average of $544). Flying from Panama City, Florida to Rome in June is currently the most expensive (average of $1,406). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to ROM?

Find hourly flight availability from Panama City to Rome. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 23, 2025.

It’s optimal to fly from Panama City, Florida to Rome in the evening. By choosing this option you can save up to 38% on the cost of your flight, compared to a flight at noon.

Reviews of airlines servicing Rome

Get insights into the airlines that provide service to Rome. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Rome. Reviews last updated November 23, 2025.
Get a feel of what it's like to fly with Delta, KLM, and United Airlines from Panama City to Rome by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,999 reviews

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Overall

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
7,999 reviews
Delta
7.9
Good
7,999 reviews

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Overall

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
KLM
7.7
Good
1,418 reviews
Delta
7.9
Good
7,999 reviews

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Overall

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
United Airlines
7.4
Good
9,033 reviews
Delta
7.9
Good
7,999 reviews

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Overall

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
11,046 reviews
Delta
7.9
Good
7,999 reviews

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Overall

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Rome. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Rome?

    Located just 16.0 mi from the city center, Panama City NW Florida Beaches is the airport most travelers will use when flying to Rome from Panama City. Booking flights from NW Florida Beaches (ECP) to Rome should be relatively easy as there are 0 daily outbound flights to Rome from 1 airline.

  • How long is the flight from Panama City, Florida to Rome?

    Airlines like United Airlines and Delta fly from Panama City, Florida to Rome in about 15h 15m. The time it takes to get you to your destination can typically vary by up to 3h 10m. There are 5228 mi between Panama City, Florida and Rome. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Panama City, Florida to Rome round-trip?

    Our cheapest airline available from Panama City, Florida to Rome is Delta. Our recent data shows that you can find tickets from as low as $729 on this airline. This flight start at 33% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Panama City, Florida to Rome one-way?

    For one-way options, check prices for KLM. According to our data, you can fly for as low as $483. Users have also found prices from $483 and $3,551 on Delta and United Airlines, respectively.

  • Can I find deals for flights from Panama City to Rome that include hotel bookings?

    Yes. In addition to deals on Panama City to Rome flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Rome?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Rome.

  • Can I find deals for business class flights from Panama City to Rome?

    Yes. Cheapflights offers flight deals from Panama City to Rome by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Rome?

    Currently, October is the cheapest month in which you can book a flight from Panama City, Florida to Rome (average of $544). Flying from Panama City, Florida to Rome in June is currently the most expensive (average of $1,406). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Rome?

Book flights to Rome if you plan to visit one of these locations
Fiumicino
Montepulciano
Santa Marinella

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Alternative routes for Panama City to Rome

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Panama City to Rome

Discover the top airline that operate flights from Panama City to Rome. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$729Average$1,150FlexibilityNo cancel feeOn-timeN/A

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