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$625+ Cheap flights from Panama City, FL (ECP) to Rome (ROM)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/31. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — ROM
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Panama City to Rome

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Rome (ROM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2025.

Round-trip from

$625
(KLM)

Popular in

May

Cheapest in

January

Average price

$827
From Panama City NW Florida Beaches to Rome (ROM)
Search Deals
Highest demand for flights based on searches. 24% potential increase in price ($361 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($78 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Panama City to Rome

Cheapest flights from Panama City to Rome
Explore the most affordable flight options available from Panama City to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This KLM deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/319:29 amECP - FCO
1 stop15h 26mKLM
Fri 11/710:05 amFCO - ECP
1 stop20h 05mKLM
Deal found 9/15$625
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/66:00 amECP - FCO
1 stop18h 35mDelta
Wed 10/2210:25 amFCO - ECP
2 stops19h 45mDelta
Deal found 9/15$626
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/317:10 amECP - FCO
2 stops16h 55mDelta
Fri 11/710:05 amFCO - ECP
1 stop16h 50mDelta
Deal found 9/15$630
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/56:00 amECP - FCO
1 stop22h 05mDelta
Wed 1/712:40 pmFCO - ECP
1 stop13h 58mDelta
Deal found 9/17$675
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/66:00 amECP - FCO
2 stops20h 20mDelta
Tue 1/610:05 amFCO - ECP
2 stops19h 37mDelta
Deal found 9/17$680
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/45:02 pmECP - FCO
1 stop31h 33mDelta
Wed 1/712:40 pmFCO - ECP
1 stop13h 58mDelta
Deal found 9/17$681
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/56:00 amECP - FCO
1 stop18h 35mDelta
Fri 1/96:00 amFCO - ECP
2 stops23h 42mDelta
Deal found 9/17$697
This Scandinavian Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Scandinavian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/141:32 pmECP - FCO
2 stops38h 33mScandinavian Airlines
Fri 1/911:55 amFCO - ECP
2 stops41h 47mScandinavian Airlines
Deal found 9/16$700

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Rome that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Panama City to Rome that are best for you.

Fly from

Panama City

Fly to

Rome

Route

Depart

Return

Price

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Fri 10/31

9:29 am-6:55 am

1 stop15h 26m

Rome Fiumicino

Fri 11/7

10:05 am-11:10 pm

1 stop20h 05m

$625

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Fri 10/31

7:10 am-6:05 am

2 stops16h 55m

Rome Fiumicino

Fri 11/7

10:05 am-7:55 pm

1 stop16h 50m

$630

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Mon 10/6

7:10 am-9:20 am

2 stops19h 10m

Rome Fiumicino

Wed 10/22

10:25 am-11:10 pm

2 stops19h 45m

$630

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Sun 10/5

6:00 am-11:05 am

1 stop22h 05m

Rome Fiumicino

Wed 1/7

12:40 pm-7:38 pm

1 stop13h 58m

$675

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Mon 10/6

6:00 am-11:05 am

1 stop22h 05m

Rome Fiumicino

Tue 1/6

10:05 am-8:20 am

2 stops29h 15m

$680

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Sun 12/14

1:32 pm-10:30 am

1 stop13h 58m

Rome Fiumicino

Wed 1/7

12:00 pm-8:20 am

2 stops27h 20m

$680

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Mon 12/15

10:00 am-7:55 am

1 stop14h 55m

Rome Fiumicino

Wed 1/7

12:00 pm-10:42 pm

2 stops17h 42m

$680

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Best time to book a flight from Panama City to Rome

Have a flexible travel schedule? Discover the best time to fly to Rome from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Rome

What is the cheapest month to book a flight from Panama City, Florida to Rome?

Currently, January is the cheapest month in which you can book a flight from Panama City, Florida to Rome (average of $644). Flying from Panama City, Florida to Rome in June is currently the most expensive (average of $1,130). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to ROM?

Find hourly flight availability from Panama City to Rome. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

It’s optimal to fly from Panama City, Florida to Rome in the afternoon. By choosing this option you can save up to 35% on the cost of your flight, compared to a flight in the morning.

How much does it cost to fly round-trip from Panama City, Florida to Rome?

Reviews of airlines servicing Rome

Get insights into the airlines that provide service to Rome. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Rome. Reviews last updated September 17, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Panama City to Rome by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,961 reviews

Overall

8.0

Boarding

8.2

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
8.0
Very good
7,961 reviews
Delta
8.0
Very good
7,961 reviews

Overall

8.0

Boarding

8.2

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
United Airlines
7.4
Good
8,926 reviews
Delta
8.0
Very good
7,961 reviews

Overall

8.0

Boarding

8.2

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,961 reviews

Overall

8.0

Boarding

8.2

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Rome. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Rome?

    Located just 16.0 mi from the city center, Panama City NW Florida Beaches is the airport most travelers will use when flying to Rome from Panama City. Booking flights from NW Florida Beaches (ECP) to Rome should be relatively easy as there are 0 daily outbound flights to Rome from 1 airline.

  • How long is the flight from Panama City, Florida to Rome?

    Airlines like KLM and Delta fly from Panama City, Florida to Rome in about 15h 26m. The time it takes to get you to your destination can typically vary by up to 1h 29m. There are 5228 mi between Panama City, Florida and Rome. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Panama City, Florida to Rome round-trip?

    Our cheapest airline available from Panama City, Florida to Rome is Delta. Our recent data shows that you can find tickets from as low as $729 on this airline. This flight start at 33% lower than the current average price 3 months from now.

  • Can I find deals for flights from Panama City to Rome that include hotel bookings?

    Yes. In addition to deals on Panama City to Rome flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Rome?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Rome.

  • Can I find deals for business class flights from Panama City to Rome?

    Yes. Cheapflights offers flight deals from Panama City to Rome by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Rome?

    Currently, January is the cheapest month in which you can book a flight from Panama City, Florida to Rome (average of $644). Flying from Panama City, Florida to Rome in June is currently the most expensive (average of $1,130). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Rome?

Book flights to Rome if you plan to visit one of these locations
Fiumicino
Gaeta
Montepulciano
Santa Marinella

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Alternative routes for Panama City to Rome

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Panama City to Rome

Discover the top airline that operate flights from Panama City to Rome. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$729Average$1,185FlexibilityNo cancel feeOn-timeN/A

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