$734+ Cheap flights from Panama City, FL (ECP) to Rome (ROM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/1. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — ROM
Nov 16 — Nov 231
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to Rome with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to Rome
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Best
Last-minute
Cheapest flights from Panama City to RomeExplore the most affordable flight options available from Panama City to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 17, 2026.
Explore the most affordable flight options available from Panama City to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 17, 2026.
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/19:05 am -
2 stops15h 40m
Wed 12/91:15 pm -
2 stops31h 02m
Deal found 10/15![United Airlines logo]()
$734
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/139:06 am -
2 stops15h 49m
Fri 11/209:55 am -
2 stops18h 41m
Deal found 10/16![United Airlines logo]()
$748
This KLM deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2411:25 am -
1 stop13h 50m
Thu 12/312:45 pm -
2 stops17h 32m
Deal found 10/12![KLM logo]()
$750
This Air France deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/241:34 pm -
2 stops14h 56m
Thu 12/312:45 pm -
2 stops17h 32m
Deal found 10/12![Multiple Airlines logo]()
$753
This Ovago deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/79:05 am -
2 stops15h 40m
Wed 12/1610:30 am -
2 stops18h 08m
Deal found 10/17![Austrian Airlines logo]()
$780
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:00 am -
1 stop19h 15m
Fri 11/201:30 pm -
1 stop14h 27m
Deal found 10/16![Delta logo]()
$782
This Ovago deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/79:05 am -
2 stops15h 40m
Wed 12/169:55 am -
2 stops34h 22m
Deal found 10/16![Lufthansa logo]()
$783
This Ovago deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/79:05 am -
2 stops15h 40m
Wed 12/169:45 am -
1 stop34h 32m
Deal found 10/16![Multiple Airlines logo]()
$786
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/299:30 am -
1 stop15h 45m
Sun 12/66:10 am -
2 stops18h 54m
Deal found 10/15![Delta logo]()
$799
Best flights from Panama City to RomeDiscover carefully curated flight deals from Panama City to Rome that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 17, 2026.
Discover carefully curated flight deals from Panama City to Rome that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 17, 2026.
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/112:10 pm -
2 stops20h 50m
Fri 1/291:15 pm -
2 stops31h 12m
Deal found 10/15![United Airlines logo]()
$741
This KLM deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2411:25 am -
1 stop13h 50m
Thu 12/312:45 pm -
2 stops17h 32m
Deal found 10/12![KLM logo]()
$750
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/117:45 am -
2 stops18h 35m
Fri 1/291:30 pm -
1 stop32h 05m
Deal found 10/15![Delta logo]()
$764
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/112:10 pm -
2 stops59h 45m
Mon 1/189:55 am -
2 stops18h 45m
Deal found 10/16![United Airlines logo]()
$747
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/117:45 am -
2 stops18h 35m
Mon 1/181:30 pm -
1 stop16h 17m
Deal found 10/16![Delta logo]()
$797
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/117:45 am -
2 stops18h 25m
Wed 3/171:30 pm -
1 stop15h 17m
Deal found 10/16![Delta logo]()
$838
Last-minute flights from Panama City to RomeDiscover last-minute flight deals from Panama City to Rome. Data last updated October 17, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Rome. Data last updated October 17, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/139:06 am -
2 stops15h 49m
Fri 11/209:55 am -
2 stops18h 41m
Deal found 10/16![United Airlines logo]()
$748
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:00 am -
1 stop19h 15m
Fri 11/201:30 pm -
1 stop14h 27m
Deal found 10/16![Delta logo]()
$782
This Icelandair deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Icelandair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:55 am -
2 stops23h 05m
Fri 11/2011:25 am -
3 stops37h 35m
Deal found 10/16![Multiple Airlines logo]()
$1,620
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/174:55 pm -
2 stops35h 00m
Fri 11/207:05 am -
2 stops21h 31m
Deal found 10/15![United Airlines logo]()
$1,102
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/204:55 pm -
2 stops32h 35m
Sat 11/2812:40 pm -
2 stops53h 12m
Deal found 10/12![United Airlines logo]()
$1,425
This KLM deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2411:25 am -
1 stop13h 50m
Thu 12/312:45 pm -
2 stops17h 32m
Deal found 10/12![KLM logo]()
$750
This Air France deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/241:34 pm -
2 stops14h 56m
Thu 12/312:45 pm -
2 stops17h 32m
Deal found 10/12![Multiple Airlines logo]()
$753
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/299:30 am -
1 stop15h 45m
Sun 12/66:10 am -
2 stops18h 54m
Deal found 10/15![Delta logo]()
$799
Find flight deals from Panama City to Rome
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Rome (ROM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 17, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $734 (United Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Rome that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 17, 2026.
Use the filters below to find and compare flights from Panama City to Rome that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityRome
ECP Panama City NW Florida Beaches - FCO Rome Fiumicino
ECPFCO
Panama City NW Florida Beaches
Mon 1/11
2:10 pm-6:00 pm
2 stops20h 50m
Rome Fiumicino
Fri 1/29
1:15 pm-1:27 pm
2 stops31h 12m
$741
Panama CityRome
ECP Panama City NW Florida Beaches - FCO Rome Fiumicino
ECPFCO
Panama City NW Florida Beaches
Mon 1/11
2:10 pm-8:55 am
2 stops59h 45m
Rome Fiumicino
Mon 1/18
9:55 am-9:40 pm
2 stops18h 45m
$747
Quickest round-trip
Panama CityRome
ECP Panama City NW Florida Beaches - FCO Rome Fiumicino
ECPFCO
Panama City NW Florida Beaches
Tue 11/24
11:25 am-8:15 am
1 stop13h 50m
Rome Fiumicino
Thu 12/3
12:45 pm-11:17 pm
2 stops17h 32m
$750
Panama CityRome
ECP Panama City NW Florida Beaches - FCO Rome Fiumicino
ECPFCO
Panama City NW Florida Beaches
Mon 1/11
7:45 am-9:20 am
2 stops18h 35m
Rome Fiumicino
Fri 1/29
1:30 pm-2:35 pm
1 stop32h 05m
$764
Panama CityRome
ECP Panama City NW Florida Beaches - FCO Rome Fiumicino
ECPFCO
Panama City NW Florida Beaches
Mon 1/11
7:45 am-9:20 am
2 stops18h 35m
Rome Fiumicino
Mon 1/18
1:30 pm-10:47 pm
1 stop16h 17m
$797
Panama CityRome
ECP Panama City NW Florida Beaches - FCO Rome Fiumicino
ECPFCO
Panama City NW Florida Beaches
Thu 3/11
7:45 am-9:10 am
2 stops18h 25m
Rome Fiumicino
Wed 3/17
1:30 pm-10:47 pm
1 stop15h 17m
$838
Sorted by cheapest first
Compare providers for flights from Panama City to Rome
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Rome in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City, Florida-Rome flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Panama City, Florida-Rome flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Rome flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City, Florida-Rome flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Rome flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to Rome
Have a flexible travel schedule? Discover the best time to fly to Rome from Panama City with our price prediction graph.
ECP-ROM
ECP-FCO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Rome
ECP-ROM
ECP-FCO
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Rome
Get insights into the airlines that provide service to Rome. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Rome. Reviews last updated October 17, 2026.
Get a feel of what it's like to fly with Delta from Panama City to Rome by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Crew
8.5
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Entertainment
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Crew
8.5
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from Panama City to Rome. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Rome?
Book flights to Rome if you plan to visit one of these locationsFiumicino
Civitavecchia
Montepulciano
Santa Marinella
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Complete your trip
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Panama City and Rome flights
Browse other Panama City and Rome flight options. Last updated on October 17, 2026.
Other flights from Panama City
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Popular flight searches
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Other flights to Rome
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Top airline flying from Panama City to Rome
Discover the top airline that operate flights from Panama City to Rome. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$722 | Average$1,539 | FlexibilityNo cancel fee | On-timeN/A |