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$366+ Cheap flights from Des Moines (DSM) to Quito (UIO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/26. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — UIO
oct. 11 — oct. 181
sáb. 10/11
sáb. 10/18
1 adult, Economy
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Cheap flight deals from Des Moines to Quito

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Quito (UIO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septiembre 11, 2025.

Round-trip from

$616
(Kiwi.com)

One-way from

$366
(American Airlines)

Popular in

June

Cheapest in

November

Average price

$965
From Des Moines to Quito Mariscal Sucr
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One-way flight from Des Moines to Quito Mariscal Sucr
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Highest demand for flights based on searches. 8% potential increase in price ($89 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($47 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Des Moines to Quito

Cheapest flights from Des Moines to Quito
Explore the most affordable flight options available from Des Moines to Quito. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 11, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/68:00 amDSM - UIO
2 stops28h 27mMultiple Airlines
jue. 10/95:15 pmUIO - DSM
1 stop21h 35mMultiple Airlines
Deal found 9/10$616
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/510:41 amDSM - UIO
2 stops35h 44mMultiple Airlines
jue. 10/95:15 pmUIO - DSM
1 stop21h 35mMultiple Airlines
Deal found 9/10$661
This Mytrip deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/268:47 pmDSM - UIO
3 stops38h 33mMultiple Airlines
dom. 11/28:05 amUIO - DSM
3 stops29h 48mMultiple Airlines
Deal found 9/11$686
This LATAM Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/265:47 amDSM - UIO
1 stop13h 08mLATAM Airlines
sáb. 11/112:55 amUIO - DSM
1 stop10h 10mLATAM Airlines
Deal found 9/11$720
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/710:50 amDSM - UIO
1 stop8h 09mDelta
jue. 10/912:59 amUIO - DSM
1 stop9h 06mDelta
Deal found 9/10$734
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/265:47 amDSM - UIO
1 stop13h 08mDelta
sáb. 11/112:55 amUIO - DSM
1 stop10h 10mDelta
Deal found 9/10$744

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Quito that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
Use the filters below to find and compare flights from Des Moines to Quito that are best for you.

Fly from

Des Moines

Fly to

Quito

Route

Depart

Return

Price

Des MoinesQuito

DSM - UIO

DSMUIO

Des Moines

dom. 10/5

10:41 am-10:25 pm

2 stops35h 44m

Quito Mariscal Sucr

jue. 10/9

5:15 pm-2:50 pm

1 stop21h 35m

$661

Des MoinesQuito

DSM - UIO

DSMUIO

Des Moines

lun. 10/6

8:30 am-5:05 pm

2 stops32h 35m

Quito Mariscal Sucr

mié. 10/8

3:55 am-2:50 pm

2 stops34h 55m

$677

Des MoinesQuito

DSM - UIO

DSMUIO

Des Moines

mar. 10/7

10:50 am-6:59 pm

1 stop8h 09m

Quito Mariscal Sucr

jue. 10/9

12:59 am-10:05 am

1 stop9h 06m

$734

Des MoinesQuito

DSM - UIO

DSMUIO

Des Moines

dom. 10/26

5:47 am-6:55 pm

1 stop13h 08m

Quito Mariscal Sucr

sáb. 11/1

12:55 am-11:05 am

1 stop10h 10m

$744

Des MoinesQuito

DSM - UIO

DSMUIO

Des Moines

lun. 10/6

5:47 am-11:20 pm

2 stops17h 33m

Quito Mariscal Sucr

jue. 10/9

9:01 am-10:05 am

2 stops25h 04m

$757

Des MoinesQuito

DSM - UIO

DSMUIO

Des Moines

dom. 10/5

6:30 pm-7:12 pm

2 stops24h 42m

Quito Mariscal Sucr

jue. 10/9

7:09 am-10:05 am

2 stops26h 56m

$757

Des MoinesQuito

DSM - UIO

DSMUIO

Des Moines

dom. 10/5

5:44 am-11:20 pm

2 stops17h 36m

Quito Mariscal Sucr

mié. 10/8

9:01 am-10:30 pm

2 stops13h 29m

$757

Des MoinesQuito

DSM - UIO

DSMUIO

Des Moines

dom. 10/5

6:15 am-11:25 pm

1 stop17h 10m

Quito Mariscal Sucr

mié. 10/8

12:35 am-2:13 pm

1 stop13h 38m

$771

Des MoinesQuito

DSM - UIO

DSMUIO

Des Moines

lun. 10/6

6:15 am-11:25 pm

1 stop17h 10m

Quito Mariscal Sucr

mié. 10/8

12:35 am-2:13 pm

1 stop13h 38m

$771

Des MoinesQuito

DSM - UIO

DSMUIO

Des Moines

dom. 10/5

6:15 am-11:25 pm

1 stop17h 10m

Quito Mariscal Sucr

mar. 10/7

12:35 am-2:13 pm

1 stop13h 38m

$771

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 12 results
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Best time to book a flight from Des Moines to Quito

Have a flexible travel schedule? Discover the best time to fly to Quito from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Quito

How much does it cost to fly round-trip from Des Moines to Quito?

Reviews of airlines servicing Quito

Get insights into the airlines that provide service to Quito. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Quito. Reviews last updated septiembre 11, 2025.
Read reviews from past customers who have flown Delta and United Airlines from Des Moines to Quito. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,937 reviews
Delta
8.0
Very good
7,960 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Quito. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Quito?

    Departing from Des Moines to Quito will take you 8h 09m. The distance between Des Moines and Quito is about 3031 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Des Moines to Quito round-trip?

    Cheapflights users have booked flights from Des Moines to Quito round-trip from $387. Another airline that can offer you cheap pricing is United Airlines. Delta is priced at 58% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Des Moines to Quito that include hotel bookings?

    Yes. In addition to deals on Des Moines to Quito flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Quito?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Quito.

  • Can I find deals for business class flights from Des Moines to Quito?

    Yes. Cheapflights offers flight deals from Des Moines to Quito by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Quito?

    Currently, April is the cheapest month in which you can book a flight from Des Moines to Quito (average of $463). Flying from Des Moines to Quito in December is currently the most expensive (average of $791). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Quito

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Top 2 airlines flying from Des Moines to Quito

Discover the top 2 airlines that operate flights from Des Moines to Quito. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$387Average$755FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$575Average$685FlexibilityNo cancel feeOn-time69%

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