$100+ Cheap flights from Missouri to Puerto Rico
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/24. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SJU
Apr 9 — Apr 161
Round-trip
1 adult, Economy
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Find cheap flights from Missouri to Puerto Rico with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to Puerto Rico
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Cheapest flights from Missouri to Puerto RicoExplore the most affordable flight options available from Missouri to Puerto Rico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.
Explore the most affordable flight options available from Missouri to Puerto Rico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.
This Frontier deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/244:51 pm
STL
- SJU
1 stop8h 12m
Frontier
Fri 4/109:10 pm
SJU
- STL
1 stop11h 41m
Frontier
Deal found 3/5![Frontier logo]()
$202
This CheapOair deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:41 am
STL
- SJU
1 stop10h 19m
Frontier
Fri 4/176:30 am
SJU
- STL
1 stop17h 49m
Frontier
Deal found 3/5![Frontier logo]()
$213
This CheapOair deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/94:55 pm
STL
- SJU
1 stop8h 06m
Frontier
Tue 5/123:08 am
SJU
- STL
1 stop21h 11m
Frontier
Deal found 3/6![Frontier logo]()
$221
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/267:12 am
STL
- SJU
1 stop14h 50m
American Airlines
Thu 4/307:00 pm
SJU
- STL
1 stop16h 16m
American Airlines
Deal found 3/5![American Airlines logo]()
$222
This Frontier deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/44:59 pm
STL
- SJU
1 stop8h 02m
Frontier
Thu 5/711:07 am
SJU
- STL
1 stop13h 12m
Frontier
Deal found 3/8![Frontier logo]()
$223
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:29 am
STL
- SJU
1 stop14h 36m
American Airlines
Thu 4/3011:59 pm
SJU
- STL
1 stop9h 55m
American Airlines
Deal found 3/9![American Airlines logo]()
$227
This Southwest deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:40 am
STL
- SJU
1 stop6h 40m
Southwest
Wed 5/135:35 am
SJU
- STL
2 stops8h 50m
Southwest
Deal found 3/5![Southwest logo]()
$232
This CheapOair deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3111:27 am
STL
- SJU
1 stop12h 30m
Frontier
Tue 4/76:30 am
SJU
- STL
1 stop17h 55m
Frontier
Deal found 3/6![Frontier logo]()
$234
This Priceline deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/314:51 pm
STL
- SJU
1 stop8h 12m
Frontier
Sat 4/49:48 am
SJU
- STL
1 stop14h 37m
Frontier
Deal found 3/5![Frontier logo]()
$239
This CheapOair deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/154:59 pm
STL
- SJU
1 stop8h 02m
Frontier
Wed 4/226:30 am
SJU
- STL
1 stop17h 49m
Frontier
Deal found 3/10![Frontier logo]()
$242
This Priceline deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/84:59 pm
STL
- SJU
1 stop8h 02m
Frontier
Sat 4/113:21 am
SJU
- STL
1 stop29h 30m
Frontier
Deal found 3/9![Frontier logo]()
$243
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:00 am
SGF
- SJU
1 stop7h 44m
United Airlines
Tue 5/57:20 am
SJU
- SGF
2 stops15h 42m
United Airlines
Deal found 3/7![United Airlines logo]()
$252
Best flights from Missouri to Puerto RicoDiscover carefully curated flight deals from Missouri to Puerto Rico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 10, 2026.
Discover carefully curated flight deals from Missouri to Puerto Rico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 10, 2026.
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:00 am
SGF
- SJU
1 stop7h 44m
United Airlines
Tue 5/57:20 am
SJU
- SGF
2 stops15h 42m
United Airlines
Deal found 3/7![United Airlines logo]()
$252
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2212:25 pm
MCI
- SJU
1 stop6h 59m
Delta
Sat 5/26:15 am
SJU
- MCI
1 stop10h 51m
Delta
Deal found 3/6![Delta logo]()
$286
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/138:25 am
MCI
- SJU
2 stops8h 45m
Southwest
Sat 5/235:15 am
SJU
- MCI
1 stop15h 00m
Southwest
Deal found 3/8![Southwest logo]()
$347
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/288:26 am
SGF
- SJU
1 stop13h 36m
American Airlines
Tue 5/55:45 am
SJU
- SGF
2 stops12h 50m
American Airlines
Deal found 3/5![American Airlines logo]()
$357
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/45:45 am
MCI
- BQN
1 stop19h 08m
Multiple Airlines
Fri 4/102:43 am
BQN
- MCI
1 stop22h 10m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$528
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/299:58 am
MCI
- BQN
2 stops12h 11m
United Airlines
Fri 5/812:15 am
BQN
- MCI
2 stops15h 11m
United Airlines
Deal found 3/7![United Airlines logo]()
$286
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/283:59 pm
SGF
- SJU
1 stop6h 14m
Delta
Tue 5/52:45 pm
SJU
- SGF
1 stop7h 22m
Delta
Deal found 3/6![Delta logo]()
$310
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/47:45 am
STL
- SJU
2 stops12h 39m
United Airlines
Thu 5/77:20 am
SJU
- STL
2 stops14h 53m
United Airlines
Deal found 3/8![United Airlines logo]()
$312
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:55 pm
MCI
- SJU
1 stop11h 00m
Southwest
Wed 4/295:05 am
SJU
- MCI
1 stop7h 45m
Southwest
Deal found 3/9![Southwest logo]()
$364
This Southwest deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/511:55 am
MCI
- SJU
1 stop11h 30m
Southwest
Mon 6/83:55 pm
SJU
- MCI
1 stop8h 30m
Southwest
Deal found 3/4![Southwest logo]()
$384
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/279:55 am
MCI
- SJU
2 stops12h 55m
United Airlines
Tue 5/51:00 am
SJU
- MCI
2 stops14h 26m
United Airlines
Deal found 3/7![United Airlines logo]()
$387
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/72:50 pm
MCI
- SJU
2 stops8h 05m
Southwest
Mon 5/118:40 pm
SJU
- MCI
1 stop12h 35m
Southwest
Deal found 3/6![Southwest logo]()
$396
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:24 pm
SGF
- SJU
1 stop15h 24m
American Airlines
Sat 4/1811:59 pm
SJU
- SGF
1 stop10h 25m
American Airlines
Deal found 3/9![American Airlines logo]()
$504
This United Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/58:00 am
MCI
- SJU
2 stops12h 24m
United Airlines
Fri 5/81:00 am
SJU
- MCI
2 stops14h 26m
United Airlines
Deal found 3/4![United Airlines logo]()
$387
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/266:15 am
MCI
- SJU
2 stops13h 23m
United Airlines
Tue 5/51:00 am
SJU
- MCI
2 stops10h 33m
United Airlines
Deal found 3/9![United Airlines logo]()
$387
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/152:25 pm
STL
- SJU
1 stop8h 00m
Southwest
Mon 5/185:35 am
SJU
- STL
2 stops10h 55m
Southwest
Deal found 3/9![Southwest logo]()
$448
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/207:54 pm
SGF
- SJU
1 stop7h 38m
American Airlines
Mon 4/271:31 pm
SJU
- SGF
2 stops10h 07m
American Airlines
Deal found 3/10![American Airlines logo]()
$570
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/37:45 am
STL
- SJU
2 stops12h 39m
United Airlines
Thu 5/77:20 am
SJU
- STL
2 stops14h 53m
United Airlines
Deal found 3/5![United Airlines logo]()
$418
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/232:50 pm
MCI
- SJU
2 stops8h 05m
Southwest
Sun 4/269:45 pm
SJU
- MCI
1 stop12h 40m
Southwest
Deal found 3/9![Southwest logo]()
$466
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/12:10 pm
STL
- SJU
2 stops8h 30m
Southwest
Sat 5/99:40 am
SJU
- STL
2 stops9h 25m
Southwest
Deal found 3/9![Southwest logo]()
$495
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:30 am
MCI
- SJU
1 stop8h 12m
United Airlines
Thu 4/237:20 am
SJU
- MCI
1 stop8h 42m
United Airlines
Deal found 3/8![United Airlines logo]()
$459
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/202:15 pm
STL
- SJU
2 stops8h 40m
Southwest
Mon 4/275:05 am
SJU
- STL
2 stops9h 40m
Southwest
Deal found 3/6![Southwest logo]()
$508
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/97:45 am
STL
- SJU
2 stops15h 05m
United Airlines
Tue 5/121:00 am
SJU
- STL
2 stops12h 47m
United Airlines
Deal found 3/6![United Airlines logo]()
$468
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/202:05 pm
STL
- SJU
1 stop6h 00m
Southwest
Sun 5/245:45 am
SJU
- STL
1 stop11h 50m
Southwest
Deal found 3/8![Southwest logo]()
$512
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:00 am
SGF
- SJU
2 stops13h 38m
United Airlines
Sat 5/27:20 am
SJU
- SGF
2 stops15h 42m
United Airlines
Deal found 3/6![United Airlines logo]()
$513
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/59:55 am
STL
- SJU
2 stops13h 20m
Southwest
Sat 6/139:25 pm
SJU
- STL
1 stop12h 00m
Southwest
Deal found 3/6![Southwest logo]()
$521
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2411:25 am
STL
- SJU
2 stops11h 11m
United Airlines
Thu 4/161:00 am
SJU
- STL
2 stops15h 48m
United Airlines
Deal found 3/5![United Airlines logo]()
$536
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/259:23 am
STL
- SJU
2 stops13h 27m
United Airlines
Thu 5/282:05 am
SJU
- STL
1 stop9h 02m
United Airlines
Deal found 3/8![United Airlines logo]()
$536
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:00 am
SGF
- SJU
2 stops14h 24m
United Airlines
Sat 4/187:40 am
SJU
- SGF
1 stop10h 44m
United Airlines
Deal found 3/6![United Airlines logo]()
$572
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1111:30 am
MCI
- BQN
2 stops10h 39m
United Airlines
Tue 4/1412:15 am
BQN
- MCI
2 stops11h 12m
United Airlines
Deal found 3/8![United Airlines logo]()
$635
Last-minute flights from Missouri to Puerto RicoDiscover last-minute flight deals from Missouri to Puerto Rico. Data last updated March 10, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Puerto Rico. Data last updated March 10, 2026 and is based on user searches.
This Priceline deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/244:51 pm
STL
- SJU
1 stop8h 12m
Frontier
Tue 4/73:16 am
SJU
- STL
1 stop21h 09m
Frontier
Deal found 3/5![Frontier logo]()
$202
This Frontier deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/264:51 pm
STL
- SJU
1 stop8h 07m
Frontier
Fri 4/109:10 pm
SJU
- STL
1 stop11h 41m
Frontier
Deal found 3/5![Frontier logo]()
$221
This CheapOair deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3111:27 am
STL
- SJU
1 stop12h 30m
Frontier
Tue 4/76:30 am
SJU
- STL
1 stop17h 55m
Frontier
Deal found 3/6![Frontier logo]()
$234
This Priceline deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/314:51 pm
STL
- SJU
1 stop8h 12m
Frontier
Sat 4/49:48 am
SJU
- STL
1 stop14h 37m
Frontier
Deal found 3/5![Frontier logo]()
$239
This Priceline deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/74:59 pm
STL
- SJU
1 stop15h 19m
Frontier
Mon 4/133:08 am
SJU
- STL
1 stop21h 11m
Frontier
Deal found 3/8![Frontier logo]()
$223
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/711:21 am
STL
- SJU
2 stops13h 40m
Frontier
Fri 4/173:23 pm
SJU
- STL
1 stop16h 27m
Frontier
Deal found 3/6![Frontier logo]()
$248
This Priceline deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/84:59 pm
STL
- SJU
1 stop8h 02m
Frontier
Sat 4/113:21 am
SJU
- STL
1 stop29h 30m
Frontier
Deal found 3/9![Frontier logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:29 pm
STL
- SJU
1 stop24h 21m
Multiple Airlines
Fri 4/173:23 pm
SJU
- STL
1 stop16h 27m
Multiple Airlines
Deal found 3/6![Multiple Airlines logo]()
$247
This CheapOair deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:41 am
STL
- SJU
1 stop10h 19m
Frontier
Fri 4/176:30 am
SJU
- STL
1 stop17h 49m
Frontier
Deal found 3/5![Frontier logo]()
$213
This CheapOair deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/154:59 pm
STL
- SJU
1 stop8h 02m
Frontier
Wed 4/226:30 am
SJU
- STL
1 stop17h 49m
Frontier
Deal found 3/10![Frontier logo]()
$242
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:29 am
STL
- SJU
1 stop14h 36m
American Airlines
Thu 4/3011:59 pm
SJU
- STL
1 stop9h 55m
American Airlines
Deal found 3/9![American Airlines logo]()
$227
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/267:12 am
STL
- SJU
1 stop14h 50m
American Airlines
Thu 4/307:00 pm
SJU
- STL
1 stop16h 16m
American Airlines
Deal found 3/5![American Airlines logo]()
$222
One-way flights from Missouri to Puerto RicoSearch for one-way flight options from Missouri to Puerto Rico. Find affordable one-way fares based on user searches. Data last updated March 10, 2026.
Search for one-way flight options from Missouri to Puerto Rico. Find affordable one-way fares based on user searches. Data last updated March 10, 2026.
This Super.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/244:51 pm
STL
- SJU
1 stop15h 03m
Frontier
Deal found 3/5![Frontier logo]()
$100
This Priceline deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/184:59 pm
STL
- SJU
1 stop8h 02m
Frontier
Deal found 3/6![Frontier logo]()
$101
This Priceline deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/94:59 pm
STL
- SJU
1 stop26h 01m
Frontier
Deal found 3/9![Frontier logo]()
$107
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1411:42 am
STL
- SJU
1 stop7h 42m
Delta
Deal found 3/9![Delta logo]()
$111
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:25 am
SGF
- SJU
1 stop8h 17m
United Airlines
Deal found 3/5![United Airlines logo]()
$115
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:15 am
MCI
- SJU
2 stops13h 23m
United Airlines
Deal found 3/9![United Airlines logo]()
$115
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:29 am
STL
- SJU
1 stop14h 36m
American Airlines
Deal found 3/9![American Airlines logo]()
$116
This Expedia deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/274:44 pm
STL
- SJU
1 stop29h 38m
Frontier
Deal found 3/9![Frontier logo]()
$117
This Frontier deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/264:51 pm
STL
- SJU
1 stop8h 07m
Frontier
Deal found 3/5![Frontier logo]()
$120
This Frontier deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/111:32 am
STL
- SJU
1 stop13h 24m
Frontier
Deal found 3/5![Frontier logo]()
$122
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/199:10 am
STL
- SJU
2 stops11h 14m
United Airlines
Deal found 3/6![United Airlines logo]()
$124
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:29 am
STL
- SJU
1 stop14h 36m
American Airlines
Deal found 3/5![American Airlines logo]()
$126
Find flight deals from Missouri to Puerto Rico
Keep the following information in mind while searching for Missouri to Puerto Rico flight deals. Data was last updated March 10, 2026.
Round-trip from | $202 (Priceline) |
|---|---|
One-way from | $100 (Super.com) |
Popular in | December |
Cheapest in | September |
Average price | $406 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Puerto Rico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
Use the filters below to find and compare flights from Missouri to Puerto Rico that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
SpringfieldSan Juan
SGF - SJU
SGFSJU
Springfield-Branson
Tue 4/28
6:00 am-2:44 pm
1 stop7h 44m
San Juan Luis Munoz Marin Intl
Tue 5/5
7:20 am-10:02 pm
2 stops15h 42m
$252
Kansas CitySan Juan
MCI - SJU
MCISJU
Kansas City
Wed 4/22
12:25 pm-8:24 pm
1 stop6h 59m
San Juan Luis Munoz Marin Intl
Sat 5/2
6:15 am-4:06 pm
1 stop10h 51m
$286
Kansas CityAguadilla
MCI - BQN
MCIBQN
Kansas City
Wed 4/29
9:58 am-11:09 pm
2 stops12h 11m
Aguadilla Borinquen
Fri 5/8
12:15 am-2:26 pm
2 stops15h 11m
$286
Quickest round-trip
SpringfieldSan Juan
SGF - SJU
SGFSJU
Springfield-Branson
Tue 4/28
3:59 pm-11:13 pm
1 stop6h 14m
San Juan Luis Munoz Marin Intl
Tue 5/5
2:45 pm-9:07 pm
1 stop7h 22m
$310
St. LouisSan Juan
STL - SJU
STLSJU
Lambert-St Louis
Mon 5/4
7:45 am-9:24 pm
2 stops12h 39m
San Juan Luis Munoz Marin Intl
Thu 5/7
7:20 am-9:13 pm
2 stops14h 53m
$312
Kansas CitySan Juan
MCI - SJU
MCISJU
Kansas City
Wed 5/13
8:25 am-6:10 pm
2 stops8h 45m
San Juan Luis Munoz Marin Intl
Sat 5/23
5:15 am-7:15 pm
1 stop15h 00m
$347
SpringfieldSan Juan
SGF - SJU
SGFSJU
Springfield-Branson
Tue 4/28
8:26 am-11:02 pm
1 stop13h 36m
San Juan Luis Munoz Marin Intl
Tue 5/5
5:45 am-5:35 pm
2 stops12h 50m
$357
Kansas CitySan Juan
MCI - SJU
MCISJU
Kansas City
Fri 4/17
8:55 pm-8:55 am
1 stop11h 00m
San Juan Luis Munoz Marin Intl
Wed 4/29
5:05 am-11:50 am
1 stop7h 45m
$364
Kansas CitySan Juan
MCI - SJU
MCISJU
Kansas City
Fri 6/5
11:55 am-12:25 am
1 stop11h 30m
San Juan Luis Munoz Marin Intl
Mon 6/8
3:55 pm-11:25 pm
1 stop8h 30m
$384
Kansas CitySan Juan
MCI - SJU
MCISJU
Kansas City
Mon 4/27
9:55 am-11:50 pm
2 stops12h 55m
San Juan Luis Munoz Marin Intl
Tue 5/5
1:00 am-2:26 pm
2 stops14h 26m
$387
Showing 1-10 of 59 resultsSorted by cheapest first
Best time to book a flight from Missouri to Puerto Rico
Have a flexible travel schedule? Discover the best time to fly to Puerto Rico from Missouri with our price prediction graph.
STL-SJU
SGF-SJU
MCI-SJU
STL-CPX
MCI-BQN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Puerto Rico
USMO-PR0
STL-SJU
SGF-SJU
MCI-SJU
STL-CPX
What is the cheapest month to book a flight from Missouri to Puerto Rico?
Currently, February is the cheapest month in which you can book a flight from Missouri to Puerto Rico (average of $128). Flying from Missouri to Puerto Rico in April is currently the most expensive (average of $246). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to PR?
Find hourly flight availability from Missouri to Puerto Rico. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 10, 2026.
When flying from Missouri to Puerto Rico, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Puerto Rico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Missouri to Puerto Rico
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Puerto Rico by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Puerto Rico by cabin class
Find flights from Missouri to Puerto Rico, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Puerto Rico flights
Browse other Missouri and Puerto Rico flight options. Last updated on March 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Missouri to Puerto Rico flights
Consider these flights traveling from Missouri to Puerto Rico.
Top 6 airlines flying from Missouri to Puerto Rico
Discover the top 6 airlines that operate flights from Missouri to Puerto Rico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$128 | Average$421 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$138 | Average$322 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$146 | Average$336 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$215 | Average$470 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$219 | Average$514 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$231 | Average$484 | FlexibilityNo cancel fee | On-time71% |