$130+ Cheap flights from Des Moines (DSM) to Puerto Rico
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/30. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SJU
Aug 27 — Sep 31
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Puerto Rico with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Des Moines to Puerto RicoExplore the most affordable flight options available from Des Moines to Puerto Rico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2026.
Explore the most affordable flight options available from Des Moines to Puerto Rico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/101:58 pm
DSM
- SJU
1 stop26h 50m
Multiple Airlines
Wed 9/1612:59 am
SJU
- DSM
1 stop19h 58m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$259
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/61:58 pm
DSM
- SJU
1 stop24h 59m
Multiple Airlines
Sat 9/1212:59 am
SJU
- DSM
1 stop19h 58m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/231:55 pm
DSM
- SJU
1 stop19h 24m
Multiple Airlines
Sun 8/306:44 am
SJU
- DSM
1 stop14h 10m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$311
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/271:55 pm
DSM
- SJU
1 stop19h 24m
Multiple Airlines
Sun 8/306:44 am
SJU
- DSM
1 stop14h 10m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$321
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:07 pm
DSM
- SJU
1 stop21h 04m
Multiple Airlines
Thu 8/136:26 am
SJU
- DSM
1 stop17h 53m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$375
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/257:15 am
DSM
- SJU
2 stops13h 45m
Southwest
Tue 9/111:50 am
SJU
- DSM
2 stops11h 05m
Southwest
Deal found 7/27![Southwest logo]()
$376
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:00 am
DSM
- SJU
2 stops12h 05m
Southwest
Thu 9/178:55 pm
SJU
- DSM
2 stops15h 30m
Southwest
Deal found 7/27![Southwest logo]()
$388
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/308:00 am
DSM
- BQN
2 stops14h 09m
United Airlines
Tue 10/612:15 am
BQN
- DSM
2 stops15h 00m
United Airlines
Deal found 7/23![United Airlines logo]()
$586
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2511:32 am
DSM
- BQN
2 stops10h 37m
United Airlines
Fri 8/2812:15 am
BQN
- DSM
2 stops13h 05m
United Airlines
Deal found 7/23![United Airlines logo]()
$636
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/207:54 am
DSM
- BQN
2 stops14h 15m
United Airlines
Sat 9/2612:15 am
BQN
- DSM
2 stops11h 16m
United Airlines
Deal found 7/23![United Airlines logo]()
$752
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/207:54 am
DSM
- BQN
2 stops14h 15m
United Airlines
Fri 9/2512:15 am
BQN
- DSM
2 stops15h 00m
United Airlines
Deal found 7/23![United Airlines logo]()
$777
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:05 am
DSM
- CPX
2 stops9h 16m
United Airlines
Fri 11/610:48 am
CPX
- DSM
2 stops35h 48m
United Airlines
Deal found 7/27![United Airlines logo]()
$1,697
Best flights from Des Moines to Puerto RicoDiscover carefully curated flight deals from Des Moines to Puerto Rico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 28, 2026.
Discover carefully curated flight deals from Des Moines to Puerto Rico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 28, 2026.
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/257:15 am
DSM
- SJU
2 stops13h 45m
Southwest
Tue 9/111:50 am
SJU
- DSM
2 stops11h 05m
Southwest
Deal found 7/27![Southwest logo]()
$376
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/222:34 pm
DSM
- SJU
1 stop6h 45m
Delta
Tue 9/292:59 pm
SJU
- DSM
1 stop8h 27m
Delta
Deal found 7/26![Delta logo]()
$466
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/236:00 am
DSM
- SJU
2 stops13h 38m
United Airlines
Sat 8/291:00 am
SJU
- DSM
2 stops12h 20m
United Airlines
Deal found 7/26![United Airlines logo]()
$505
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:10 pm
DSM
- SJU
2 stops13h 10m
Southwest
Mon 10/1910:50 pm
SJU
- DSM
2 stops13h 40m
Southwest
Deal found 7/25![Southwest logo]()
$466
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2711:28 am
DSM
- SJU
1 stop10h 01m
Delta
Thu 9/37:00 am
SJU
- DSM
1 stop9h 16m
Delta
Deal found 7/26![Delta logo]()
$486
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:40 am
DSM
- SJU
2 stops13h 25m
Southwest
Thu 9/178:55 pm
SJU
- DSM
2 stops15h 30m
Southwest
Deal found 7/27![Southwest logo]()
$489
This Delta deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:40 am
DSM
- SJU
1 stop7h 02m
Delta
Sat 8/2912:56 pm
SJU
- DSM
1 stop10h 41m
Delta
Deal found 7/24![Delta logo]()
$506
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/308:00 am
DSM
- BQN
2 stops14h 09m
United Airlines
Tue 10/612:15 am
BQN
- DSM
2 stops15h 00m
United Airlines
Deal found 7/23![United Airlines logo]()
$586
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2511:32 am
DSM
- BQN
2 stops10h 37m
United Airlines
Fri 8/2812:15 am
BQN
- DSM
2 stops13h 05m
United Airlines
Deal found 7/23![United Airlines logo]()
$636
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/207:54 am
DSM
- BQN
2 stops14h 15m
United Airlines
Sat 9/2612:15 am
BQN
- DSM
2 stops11h 16m
United Airlines
Deal found 7/23![United Airlines logo]()
$752
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:05 am
DSM
- CPX
2 stops9h 16m
United Airlines
Fri 11/610:48 am
CPX
- DSM
2 stops35h 48m
United Airlines
Deal found 7/27![United Airlines logo]()
$1,697
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/263:15 pm
DSM
- CPX
2 stops25h 06m
United Airlines
Fri 10/3010:48 am
CPX
- DSM
2 stops12h 42m
United Airlines
Deal found 7/26![United Airlines logo]()
$1,702
Last-minute flights from Des Moines to Puerto RicoDiscover last-minute flight deals from Des Moines to Puerto Rico. Data last updated July 28, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Puerto Rico. Data last updated July 28, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/48:00 am
DSM
- BQN
2 stops14h 09m
United Airlines
Mon 8/1012:15 am
BQN
- DSM
2 stops11h 11m
United Airlines
Deal found 7/28![United Airlines logo]()
$992
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:07 pm
DSM
- SJU
1 stop21h 04m
Multiple Airlines
Thu 8/136:26 am
SJU
- DSM
1 stop17h 53m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$375
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:07 pm
DSM
- SJU
1 stop21h 04m
Multiple Airlines
Sun 8/236:44 am
SJU
- DSM
1 stop14h 10m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$414
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/231:55 pm
DSM
- SJU
1 stop19h 24m
Multiple Airlines
Sun 8/306:44 am
SJU
- DSM
1 stop14h 10m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$311
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:55 am
DSM
- SJU
1 stop15h 20m
American Airlines
Mon 8/317:03 am
SJU
- DSM
1 stop16h 03m
American Airlines
Deal found 7/26![American Airlines logo]()
$466
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/257:15 am
DSM
- SJU
2 stops13h 45m
Southwest
Tue 9/111:50 am
SJU
- DSM
2 stops11h 05m
Southwest
Deal found 7/27![Southwest logo]()
$376
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2511:32 am
DSM
- BQN
2 stops10h 37m
United Airlines
Fri 8/2812:15 am
BQN
- DSM
2 stops13h 05m
United Airlines
Deal found 7/23![United Airlines logo]()
$636
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/271:55 pm
DSM
- SJU
1 stop19h 24m
Multiple Airlines
Sun 8/306:44 am
SJU
- DSM
1 stop14h 10m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$321
One-way flights from Des Moines to Puerto RicoSearch for one-way flight options from Des Moines to Puerto Rico. Find affordable one-way fares based on user searches. Data last updated July 28, 2026.
Search for one-way flight options from Des Moines to Puerto Rico. Find affordable one-way fares based on user searches. Data last updated July 28, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/301:55 pm
DSM
- SJU
1 stop19h 24m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$130
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:40 am
DSM
- SJU
2 stops13h 25m
Southwest
Deal found 7/25![Southwest logo]()
$233
This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/24:57 pm
DSM
- SJU
1 stop9h 02m
Multiple Airlines
Deal found 7/25![Multiple Airlines logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/253:04 pm
DSM
- SJU
3 stops45h 30m
Multiple Airlines
Deal found 7/25![Multiple Airlines logo]()
$249
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:40 am
DSM
- SJU
2 stops13h 25m
Southwest
Deal found 7/27![Southwest logo]()
$250
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:50 am
DSM
- SJU
2 stops12h 15m
Southwest
Deal found 7/25![Southwest logo]()
$253
This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/39:00 am
DSM
- SJU
3 stops51h 34m
Multiple Airlines
Deal found 7/25![Multiple Airlines logo]()
$265
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:00 am
DSM
- SJU
1 stop7h 44m
United Airlines
Deal found 7/25![United Airlines logo]()
$273
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/25:10 am
DSM
- SJU
2 stops10h 15m
Southwest
Deal found 7/25![Southwest logo]()
$309
Find flight deals from Des Moines to Puerto Rico
Keep the following information in mind while searching for Des Moines to Puerto Rico flight deals. Data was last updated July 28, 2026.
Round-trip from | $259 (Kiwi.com) |
|---|---|
One-way from | $130 (Kiwi.com) |
Popular in | December |
Cheapest in | January |
Average price | $561 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Puerto Rico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2026.
Use the filters below to find and compare flights from Des Moines to Puerto Rico that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesSan Juan
DSM - SJU
DSMSJU
Des Moines
Tue 8/25
7:15 am-10:00 pm
2 stops13h 45m
San Juan Luis Munoz Marin Intl
Tue 9/1
11:50 am-9:55 pm
2 stops11h 05m
$376
Quickest round-trip
Des MoinesSan Juan
DSM - SJU
DSMSJU
Des Moines
Tue 9/22
2:34 pm-10:19 pm
1 stop6h 45m
San Juan Luis Munoz Marin Intl
Tue 9/29
2:59 pm-10:26 pm
1 stop8h 27m
$466
Des MoinesSan Juan
DSM - SJU
DSMSJU
Des Moines
Thu 10/15
7:10 pm-9:20 am
2 stops13h 10m
San Juan Luis Munoz Marin Intl
Mon 10/19
10:50 pm-11:30 am
2 stops13h 40m
$466
Des MoinesSan Juan
DSM - SJU
DSMSJU
Des Moines
Thu 8/27
11:28 am-10:29 pm
1 stop10h 01m
San Juan Luis Munoz Marin Intl
Thu 9/3
7:00 am-3:16 pm
1 stop9h 16m
$486
Des MoinesSan Juan
DSM - SJU
DSMSJU
Des Moines
Thu 9/10
5:40 am-8:05 pm
2 stops13h 25m
San Juan Luis Munoz Marin Intl
Thu 9/17
8:55 pm-11:25 am
2 stops15h 30m
$489
Des MoinesSan Juan
DSM - SJU
DSMSJU
Des Moines
Sun 8/23
6:00 am-8:38 pm
2 stops13h 38m
San Juan Luis Munoz Marin Intl
Sat 8/29
1:00 am-12:20 pm
2 stops12h 20m
$505
Des MoinesSan Juan
DSM - SJU
DSMSJU
Des Moines
Sat 8/22
5:40 am-1:42 pm
1 stop7h 02m
San Juan Luis Munoz Marin Intl
Sat 8/29
12:56 pm-10:37 pm
1 stop10h 41m
$506
Des MoinesAguadilla
DSM - BQN
DSMBQN
Des Moines
Wed 9/30
8:00 am-11:09 pm
2 stops14h 09m
Aguadilla Borinquen
Tue 10/6
12:15 am-2:15 pm
2 stops15h 00m
$586
Des MoinesAguadilla
DSM - BQN
DSMBQN
Des Moines
Tue 8/25
11:32 am-11:09 pm
2 stops10h 37m
Aguadilla Borinquen
Fri 8/28
12:15 am-12:20 pm
2 stops13h 05m
$636
Des MoinesAguadilla
DSM - BQN
DSMBQN
Des Moines
Sun 9/20
7:54 am-11:09 pm
2 stops14h 15m
Aguadilla Borinquen
Sat 9/26
12:15 am-10:31 am
2 stops11h 16m
$752
Showing 1-10 of 22 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Puerto Rico
Have a flexible travel schedule? Discover the best time to fly to Puerto Rico from Des Moines with our price prediction graph.
DSM-SJU
DSM-BQN
DSM-CPX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Puerto Rico
DSM-PR0
DSM-SJU
DSM-BQN
DSM-CPX
What is the cheapest month to book a flight from Des Moines to Puerto Rico?
Currently, January is the cheapest month in which you can book a flight from Des Moines to Puerto Rico (average of $493). Flying from Des Moines to Puerto Rico in December is currently the most expensive (average of $805). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from Des Moines to Puerto Rico?
To ensure you get the cheapest price possible for a flight from Des Moines to Puerto Rico, you should look to book at least 25 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing Puerto Rico
Get insights into the airlines that provide service to Puerto Rico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Puerto Rico. Reviews last updated July 28, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from Des Moines to Puerto Rico to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Entertainment
7.8
Boarding
8.1
Crew
8.5
Comfort
7.8
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Entertainment
7.8
Boarding
8.1
Crew
8.5
Comfort
7.8
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Entertainment
7.8
Boarding
8.1
Crew
8.5
Comfort
7.8
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Food
7.2
Entertainment
7.8
Boarding
8.1
Crew
8.5
Comfort
7.8
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Puerto Rico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to Puerto Rico
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Complete your trip
Complete your trip to Puerto Rico by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Des Moines to Puerto Rico, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Puerto Rico flights
Browse other Des Moines and Puerto Rico flight options. Last updated on July 28, 2026.
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Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Des Moines to Puerto Rico
Discover the top 3 airlines that operate flights from Des Moines to Puerto Rico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$396 | Average$651 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$396 | Average$579 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$413 | Average$594 | FlexibilityNo cancel fee | On-time69% |