$143+ Cheap flights from Des Moines (DSM) to Puerto Rico
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/11. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SJU
Oct 10 — Oct 171
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Puerto Rico with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Puerto Rico
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Cheapest flights from Des Moines to Puerto RicoExplore the most affordable flight options available from Des Moines to Puerto Rico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
Explore the most affordable flight options available from Des Moines to Puerto Rico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/188:43 am -
1 stop14h 11m
Thu 10/226:15 am -
1 stop9h 27m
Deal found 9/10![Multiple Airlines logo]()
$208
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:40 am -
1 stop10h 08m
Thu 10/86:15 am -
1 stop9h 27m
Deal found 9/7![Multiple Airlines logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/241:58 pm -
1 stop9h 03m
Sat 9/2612:59 am -
1 stop19h 58m
Deal found 9/7![Multiple Airlines logo]()
$396
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:25 pm -
2 stops36h 54m
Thu 10/156:15 am -
1 stop9h 27m
Deal found 9/8![Multiple Airlines logo]()
$407
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/179:00 am -
1 stop13h 05m
Sat 10/247:15 am -
1 stop31h 44m
Deal found 9/6![Multiple Airlines logo]()
$412
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/512:59 pm -
1 stop20h 54m
Wed 12/96:25 pm -
2 stops24h 21m
Deal found 9/10![Multiple Airlines logo]()
$427
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/242:27 pm -
1 stop21h 32m
Thu 12/107:25 am -
1 stop11h 21m
Deal found 9/6![Multiple Airlines logo]()
$430
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/272:35 pm -
2 stops13h 38m
Thu 12/107:25 am -
1 stop11h 21m
Deal found 9/6![Multiple Airlines logo]()
$438
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/258:00 am -
2 stops14h 09m
Mon 9/2812:15 am -
2 stops13h 19m
Deal found 9/10![United Airlines logo]()
$658
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/268:00 am -
2 stops13h 57m
Thu 10/2912:09 am -
2 stops15h 17m
Deal found 9/9![United Airlines logo]()
$666
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3011:27 am -
2 stops10h 42m
Tue 10/612:15 am -
2 stops13h 19m
Deal found 9/9![United Airlines logo]()
$701
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/511:27 am -
2 stops10h 42m
Thu 10/812:15 am -
2 stops11h 16m
Deal found 9/7![United Airlines logo]()
$728
Best flights from Des Moines to Puerto RicoDiscover carefully curated flight deals from Des Moines to Puerto Rico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
Discover carefully curated flight deals from Des Moines to Puerto Rico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:10 pm -
2 stops15h 40m
Fri 10/912:35 pm -
2 stops11h 40m
Deal found 9/7![Southwest logo]()
$458
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/79:55 am -
2 stops10h 27m
Tue 11/178:05 am -
2 stops11h 23m
Deal found 9/10![United Airlines logo]()
$476
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/2510:15 am -
2 stops11h 35m
Mon 2/17:30 am -
2 stops11h 20m
Deal found 9/8![Delta logo]()
$486
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/257:52 pm -
1 stop7h 08m
Sat 3/611:38 am -
2 stops12h 13m
Deal found 9/5![American Airlines logo]()
$511
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/246:55 am -
2 stops13h 05m
Sun 1/317:35 am -
2 stops15h 45m
Deal found 9/6![Southwest logo]()
$466
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/2311:28 am -
1 stop7h 32m
Fri 1/292:05 am -
2 stops12h 22m
Deal found 9/5![United Airlines logo]()
$486
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:35 am -
1 stop10h 14m
Tue 10/136:45 am -
2 stops14h 55m
Deal found 9/7![Delta logo]()
$511
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/246:00 am -
2 stops13h 13m
Sun 1/316:17 am -
1 stop9h 04m
Deal found 9/5![American Airlines logo]()
$516
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:35 am -
2 stops14h 00m
Tue 10/135:05 am -
2 stops13h 45m
Deal found 9/7![Southwest logo]()
$483
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/185:20 am -
2 stops15h 20m
Sat 2/277:30 am -
2 stops15h 00m
Deal found 9/10![Southwest logo]()
$503
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3011:27 am -
2 stops10h 42m
Tue 10/612:15 am -
2 stops13h 19m
Deal found 9/6![United Airlines logo]()
$666
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/268:00 am -
2 stops13h 57m
Thu 10/2912:09 am -
2 stops15h 17m
Deal found 9/8![United Airlines logo]()
$666
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/511:27 am -
2 stops10h 42m
Thu 10/812:15 am -
2 stops11h 16m
Deal found 9/7![United Airlines logo]()
$728
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/238:00 am -
2 stops14h 09m
Sat 9/2612:15 am -
2 stops13h 17m
Deal found 9/8![United Airlines logo]()
$748
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:36 am -
2 stops10h 33m
Sun 9/2712:15 am -
2 stops13h 19m
Deal found 9/9![United Airlines logo]()
$748
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/258:00 am -
3 stops14h 09m
Mon 9/2812:15 am -
2 stops11h 16m
Deal found 9/10![United Airlines logo]()
$761
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/207:54 am -
2 stops14h 15m
Fri 9/2512:15 am -
2 stops13h 17m
Deal found 9/5![United Airlines logo]()
$771
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2011:32 am -
2 stops10h 37m
Sat 9/2612:15 am -
2 stops13h 17m
Deal found 9/8![United Airlines logo]()
$822
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/306:30 pm -
2 stops44h 51m
Wed 2/310:48 am -
2 stops14h 28m
Deal found 9/8![United Airlines logo]()
$2,171
Last-minute flights from Des Moines to Puerto RicoDiscover last-minute flight deals from Des Moines to Puerto Rico. Data last updated September 10, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Puerto Rico. Data last updated September 10, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/241:58 pm -
1 stop9h 03m
Sat 9/2612:59 am -
1 stop19h 58m
Deal found 9/7![Multiple Airlines logo]()
$396
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/258:00 am -
2 stops14h 09m
Mon 9/2812:15 am -
2 stops13h 19m
Deal found 9/10![United Airlines logo]()
$658
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3011:27 am -
2 stops10h 42m
Tue 10/612:15 am -
2 stops13h 19m
Deal found 9/9![United Airlines logo]()
$701
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:40 am -
1 stop10h 08m
Thu 10/86:15 am -
1 stop9h 27m
Deal found 9/7![Multiple Airlines logo]()
$263
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/54:30 pm -
2 stops15h 40m
Mon 10/1210:50 pm -
2 stops13h 40m
Deal found 9/6![Southwest logo]()
$450
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:10 pm -
2 stops15h 40m
Fri 10/912:35 pm -
2 stops11h 40m
Deal found 9/7![Southwest logo]()
$458
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/511:27 am -
2 stops10h 42m
Thu 10/812:15 am -
2 stops11h 16m
Deal found 9/7![United Airlines logo]()
$728
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:25 pm -
2 stops36h 54m
Thu 10/156:15 am -
1 stop9h 27m
Deal found 9/8![Multiple Airlines logo]()
$407
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/179:00 am -
1 stop13h 05m
Sat 10/247:15 am -
1 stop31h 44m
Deal found 9/6![Multiple Airlines logo]()
$412
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/188:43 am -
1 stop14h 11m
Thu 10/226:15 am -
1 stop9h 27m
Deal found 9/10![Multiple Airlines logo]()
$208
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:10 pm -
2 stops13h 30m
Fri 10/3010:10 am -
2 stops14h 05m
Deal found 9/8![Southwest logo]()
$466
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/268:00 am -
2 stops13h 57m
Thu 10/2912:09 am -
2 stops15h 17m
Deal found 9/9![United Airlines logo]()
$666
One-way flights from Des Moines to Puerto RicoSearch for one-way flight options from Des Moines to Puerto Rico. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
Search for one-way flight options from Des Moines to Puerto Rico. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/118:43 am -
1 stop24h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$143
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:45 am -
2 stops26h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$173
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:10 pm -
2 stops15h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Southwest logo]()
$225
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:00 am -
2 stops12h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Southwest logo]()
$253
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:25 pm -
2 stops36h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Frontier logo]()
$274
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/51:15 pm -
1 stop8h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![American Airlines logo]()
$278
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/104:12 pm -
2 stops16h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![American Airlines logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/93:04 pm -
3 stops33h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$289
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/51:02 pm -
3 stops26h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$319
This deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:00 am -
1 stop11h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![United Airlines logo]()
$320
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/241:58 pm -
2 stops43h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$409
Find flight deals from Des Moines to Puerto Rico
Keep the following information in mind while searching for Des Moines to Puerto Rico flight deals. Data was last updated September 10, 2026.
Round-trip from | $263 (Kiwi.com) |
|---|---|
One-way from | $143 (Kiwi.com) |
Popular in | December |
Cheapest in | January |
Average price | $501 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Puerto Rico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
Use the filters below to find and compare flights from Des Moines to Puerto Rico that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesSan Juan
DSM Des Moines - SJU San Juan Luis Munoz Marin Intl
DSMSJU
Des Moines
Mon 10/5
7:10 pm-11:50 am
2 stops15h 40m
San Juan Luis Munoz Marin Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$225
Des MoinesSan Juan
DSM Des Moines - SJU San Juan Luis Munoz Marin Intl
DSMSJU
Des Moines
Sat 10/17
7:00 am-8:10 pm
2 stops12h 10m
San Juan Luis Munoz Marin Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$253
Des MoinesSan Juan
DSM Des Moines - SJU San Juan Luis Munoz Marin Intl
DSMSJU
Des Moines
Fri 10/9
8:25 pm-10:19 am
2 stops36h 54m
San Juan Luis Munoz Marin Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$274
Des MoinesSan Juan
DSM Des Moines - SJU San Juan Luis Munoz Marin Intl
DSMSJU
Des Moines
Fri 10/9
3:04 pm-2:09 am
3 stops34h 05m
San Juan Luis Munoz Marin Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$278
Quickest round-trip
Des MoinesSan Juan
DSM Des Moines - SJU San Juan Luis Munoz Marin Intl
DSMSJU
Des Moines
Mon 10/5
1:15 pm-10:57 pm
1 stop8h 42m
San Juan Luis Munoz Marin Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$278
Des MoinesSan Juan
DSM Des Moines - SJU San Juan Luis Munoz Marin Intl
DSMSJU
Des Moines
Sat 10/10
4:12 pm-9:46 am
2 stops16h 34m
San Juan Luis Munoz Marin Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$284
Des MoinesSan Juan
DSM Des Moines - SJU San Juan Luis Munoz Marin Intl
DSMSJU
Des Moines
Fri 10/9
7:31 pm-2:03 pm
1 stop17h 32m
San Juan Luis Munoz Marin Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$319
Des MoinesCulebra
DSM Des Moines - CPX Culebra
DSMCPX
Des Moines
Thu 9/24
1:58 pm-10:22 am
2 stops43h 24m
Culebra
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$409
Des MoinesSan Juan
DSM Des Moines - SJU San Juan Luis Munoz Marin Intl
DSMSJU
Des Moines
Mon 10/5
7:10 pm-11:50 am
2 stops15h 40m
San Juan Luis Munoz Marin Intl
Fri 10/9
12:35 pm-11:15 pm
2 stops11h 40m
$458
Des MoinesSan Juan
DSM Des Moines - SJU San Juan Luis Munoz Marin Intl
DSMSJU
Des Moines
Sun 1/24
6:55 am-10:00 pm
2 stops13h 05m
San Juan Luis Munoz Marin Intl
Sun 1/31
7:35 am-9:20 pm
2 stops15h 45m
$466
Showing 1-10 of 30 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Puerto Rico
Have a flexible travel schedule? Discover the best time to fly to Puerto Rico from Des Moines with our price prediction graph.
DSM-SJU
DSM-CPX
DSM-BQN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Puerto Rico
DSM-PR0
DSM-SJU
DSM-CPX
DSM-BQN
What is the cheapest month to book a flight from Des Moines to Puerto Rico?
Currently, January is the cheapest month in which you can book a flight from Des Moines to Puerto Rico (average of $493). Flying from Des Moines to Puerto Rico in December is currently the most expensive (average of $825). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from Des Moines to Puerto Rico?
To ensure you get the cheapest price possible for a flight from Des Moines to Puerto Rico, you should look to book at least 23 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing Puerto Rico
Get insights into the airlines that provide service to Puerto Rico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Puerto Rico. Reviews last updated September 10, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Des Moines to Puerto Rico to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Food
7.0
Overall
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Comfort
8.0
Food
7.0
Overall
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Comfort
8.0
Food
7.0
Overall
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Comfort
8.0
Food
7.0
Overall
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Comfort
8.0
Food
7.0
Overall
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Puerto Rico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to Puerto Rico
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Puerto Rico by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Des Moines to Puerto Rico by cabin class
Find flights from Des Moines to Puerto Rico, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Puerto Rico flights
Browse other Des Moines and Puerto Rico flight options. Last updated on September 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Des Moines to Puerto Rico
Discover the top 4 airlines that operate flights from Des Moines to Puerto Rico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$397 | Average$651 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$401 | Average$771 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$406 | Average$588 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$413 | Average$586 | FlexibilityNo cancel fee | On-time69% |