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Prague

$289+ Cheap flights from South Carolina to Prague (PRG)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/28. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — PRG
Apr 21 — Apr 281
Tue 4/21
Tue 4/28
1 adult, Economy
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Cheap flight deals from South Carolina to Prague

Cheapest flights from South Carolina to Prague
Explore the most affordable flight options available from South Carolina to Prague. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 22, 2026.

This Scandinavian Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Scandinavian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1710:00 am
CLT
-
PRG
2 stops28h 15m
Scandinavian Airlines
Thu 10/110:20 am
PRG
-
CLT
2 stops18h 03m
Scandinavian Airlines
Deal found 3/17$664
This FlightHub deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:00 am
CLT
-
PRG
2 stops21h 40m
Scandinavian Airlines
Mon 9/283:20 pm
PRG
-
CLT
2 stops36h 42m
Scandinavian Airlines
Deal found 3/17$672
This Air Canada deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/163:40 pm
CLT
-
PRG
1 stop13h 10m
Air Canada
Wed 8/2612:30 pm
PRG
-
CLT
2 stops39h 00m
Air Canada
Deal found 3/20$674
This Gotogate deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:40 pm
CLT
-
PRG
1 stop12h 05m
Multiple Airlines
Tue 8/256:10 am
PRG
-
CLT
2 stops20h 47m
Multiple Airlines
Deal found 3/21$675
This Scandinavian Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Scandinavian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/44:30 pm
CHS
-
PRG
2 stops35h 15m
Scandinavian Airlines
Tue 12/83:00 pm
PRG
-
CHS
2 stops36h 46m
Scandinavian Airlines
Deal found 3/17$676
This American Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1911:50 pm
CLT
-
PRG
1 stop17h 05m
American Airlines
Tue 8/2510:15 am
PRG
-
CLT
1 stop13h 35m
American Airlines
Deal found 3/21$677
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1211:50 pm
CLT
-
PRG
1 stop11h 15m
American Airlines
Wed 8/1910:15 am
PRG
-
CLT
2 stops16h 38m
American Airlines
Deal found 3/20$681
This Trip.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/227:12 am
CLT
-
PRG
2 stops29h 13m
Multiple Airlines
Wed 5/63:20 pm
PRG
-
CLT
2 stops37h 44m
Multiple Airlines
Deal found 3/21$682
This FlightHub deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:40 pm
CLT
-
PRG
1 stop20h 40m
Lufthansa
Wed 8/199:35 am
PRG
-
CLT
1 stop13h 10m
Lufthansa
Deal found 3/18$684
This United Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:40 pm
CLT
-
PRG
1 stop15h 25m
United Airlines
Fri 8/216:15 am
PRG
-
CLT
1 stop16h 30m
United Airlines
Deal found 3/20$686
This FlightHub deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:50 pm
CLT
-
PRG
1 stop12h 15m
Lufthansa
Fri 12/113:10 pm
PRG
-
CLT
2 stops15h 40m
Lufthansa
Deal found 3/19$687
This oojo deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/611:20 am
SAV
-
PRG
2 stops25h 05m
Turkish Airlines
Sun 5/249:15 am
PRG
-
SAV
2 stops30h 42m
Turkish Airlines
Deal found 3/20$749

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Prague that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
Use the filters below to find and compare flights from South Carolina to Prague that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Sun 8/9

6:00 am-10:50 am

2 stops22h 50m

Václav Havel Prague

Tue 8/18

1:25 pm-4:45 pm

1 stop33h 20m

$702

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Mon 5/4

6:40 pm-12:45 pm

1 stop12h 05m

Václav Havel Prague

Mon 5/11

4:40 pm-4:45 pm

1 stop30h 05m

$751

SavannahPrague

SAV - PRG

SAVPRG

Savannah/Hilton Head

Tue 7/28

9:50 am-4:05 pm

2 stops24h 15m

Václav Havel Prague

Tue 8/18

1:25 pm-7:50 pm

2 stops36h 25m

$773

GreenvillePrague

GSP - PRG

GSPPRG

Greenville

Tue 8/25

5:43 pm-4:05 pm

2 stops16h 22m

Václav Havel Prague

Sat 12/12

7:35 am-9:11 pm

2 stops19h 36m

$798

SavannahPrague

SAV - PRG

SAVPRG

Savannah/Hilton Head

Tue 5/5

6:36 pm-7:35 pm

2 stops18h 59m

Václav Havel Prague

Tue 5/12

11:00 am-9:32 pm

1 stop16h 32m

$803

GreenvillePrague

GSP - PRG

GSPPRG

Greenville

Tue 5/5

5:50 pm-7:35 pm

2 stops19h 45m

Václav Havel Prague

Tue 5/12

11:00 am-9:04 am

2 stops28h 04m

$808

GreenvillePrague

GSP - PRG

GSPPRG

Greenville

Mon 8/24

6:47 am-6:45 pm

2 stops29h 58m

Václav Havel Prague

Mon 8/31

7:30 pm-10:15 pm

2 stops32h 45m

$812

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Sat 8/15

3:57 pm-10:50 am

2 stops36h 53m

Václav Havel Prague

Sat 8/29

12:30 pm-11:58 pm

2 stops41h 28m

$839

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Mon 5/11

8:05 am-1:55 pm

2 stops23h 50m

Václav Havel Prague

Mon 5/25

7:30 pm-4:45 pm

2 stops27h 15m

$844

GreenvillePrague

GSP - PRG

GSPPRG

Greenville

Mon 8/24

2:42 pm-8:15 am

1 stop11h 33m

Václav Havel Prague

Mon 8/31

10:15 am-9:38 pm

1 stop17h 23m

$846

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/18

Showing 1-10 of 47 resultsSorted by cheapest first
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Best time to book a flight from South Carolina to Prague

Have a flexible travel schedule? Discover the best time to fly to Prague from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Prague

What is the cheapest month to book a flight from South Carolina to Prague?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Prague (average of $506). Flying from South Carolina to Prague in June is currently the most expensive (average of $1,016). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Prague. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Prague from South Carolina?

    Most people fly into Václav Havel Prague (PRG) if they book a flight to Prague from South Carolina. Václav Havel Prague is conveniently located just 6.9 mi from Prague’s city center.

  • How long is the flight from South Carolina to Prague?

    There are many flights that can get you from South Carolina to Prague in 12h 05m. Fly via United Airlines, Lufthansa, or Delta to get the fastest option. South Carolina and Prague are separated by a distance of 4608 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from South Carolina to Prague?

    The most popular route from South Carolina to Prague is Charlotte Douglas - Václav Havel Prague. You may also consider Greenville - Václav Havel Prague or Charleston - Václav Havel Prague.

  • Can I find deals for flights from South Carolina to Prague that include hotel bookings?

    Yes. In addition to deals on South Carolina to Prague flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Prague?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Prague.

  • Can I find deals for business class flights from South Carolina to Prague?

    Yes. Cheapflights offers flight deals from South Carolina to Prague by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Prague?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Prague (average of $506). Flying from South Carolina to Prague in June is currently the most expensive (average of $1,016). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 3 airlines flying from South Carolina to Prague

Discover the top 3 airlines that operate flights from South Carolina to Prague. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$485Average$485FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$693Average$906FlexibilityNo cancel feeOn-time69%
DeltaCheapest$735Average$886FlexibilityNo cancel feeOn-timeN/A

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