Prague

$350+ Cheap flights from South Carolina to Prague (PRG)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/25. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — PRG
Jul 15 — Jul 221
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Cheap flight deals from South Carolina to Prague

Cheapest flights from South Carolina to Prague
Explore the most affordable flight options available from South Carolina to Prague. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 15, 2026.

This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/178:15 pm
CLT
-
PRG
1 stop11h 00m
American Airlines
Tue 8/2510:15 am
PRG
-
CLT
1 stop13h 39m
American Airlines
Deal found 6/11$706
This KLM deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1210:01 am
CLT
-
PRG
1 stop16h 59m
Multiple Airlines
Wed 8/1911:00 am
PRG
-
CLT
1 stop13h 51m
Multiple Airlines
Deal found 6/10$714
This KLM deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/121:49 pm
CLT
-
PRG
1 stop13h 11m
KLM
Wed 8/1911:00 am
PRG
-
CLT
1 stop17h 58m
KLM
Deal found 6/14$715
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1211:50 am
CLT
-
PRG
2 stops17h 00m
Delta
Wed 8/1911:00 am
PRG
-
CLT
1 stop13h 51m
Delta
Deal found 6/10$718
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:28 pm
CLT
-
PRG
2 stops14h 27m
American Airlines
Tue 11/246:45 am
PRG
-
CLT
1 stop13h 35m
American Airlines
Deal found 6/12$720
This Finnair deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:25 pm
CLT
-
PRG
2 stops18h 25m
Multiple Airlines
Wed 11/2511:40 am
PRG
-
CLT
2 stops26h 56m
Multiple Airlines
Deal found 6/10$723
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/18:15 pm
CLT
-
PRG
1 stop15h 15m
American Airlines
Fri 12/1111:00 am
PRG
-
CLT
2 stops16h 27m
American Airlines
Deal found 6/15$725
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:59 pm
CLT
-
PRG
2 stops16h 06m
Delta
Fri 12/116:00 am
PRG
-
CLT
2 stops18h 16m
Delta
Deal found 6/12$726
This Finnair deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:15 pm
CLT
-
PRG
2 stops16h 35m
Finnair
Mon 11/237:35 pm
PRG
-
CLT
2 stops26h 30m
Finnair
Deal found 6/11$731
This oojo deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/45:55 pm
CHS
-
PRG
2 stops14h 25m
Scandinavian Airlines
Tue 11/243:00 pm
PRG
-
CHS
2 stops36h 46m
Scandinavian Airlines
Deal found 6/12$788
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/63:00 pm
SAV
-
PRG
2 stops20h 55m
United Airlines
Thu 12/107:15 am
PRG
-
SAV
2 stops19h 55m
United Airlines
Deal found 6/11$812
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/110:20 am
CAE
-
PRG
2 stops23h 45m
United Airlines
Thu 11/511:30 am
PRG
-
CAE
2 stops28h 17m
United Airlines
Deal found 6/10$812

Find flight deals from South Carolina to Prague

Keep the following information in mind while searching for South Carolina to Prague flight deals. Data was last updated June 15, 2026.

Round-trip from

$706
(American Airlines)

One-way from

$350
(Kiwi.com)
From South Carolina to Václav Havel Prague
One-way flight from South Carolina to Václav Havel Prague

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Prague that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 15, 2026.
Use the filters below to find and compare flights from South Carolina to Prague that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Wed 8/12

1:49 pm-9:00 am

1 stop13h 11m

Václav Havel Prague

Wed 8/19

11:00 am-10:58 pm

1 stop17h 58m

$715

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Wed 8/12

6:45 am-9:00 am

2 stops20h 15m

Václav Havel Prague

Wed 8/19

11:00 am-11:57 pm

2 stops18h 57m

$719

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Mon 7/27

1:52 pm-10:50 am

2 stops14h 58m

Václav Havel Prague

Thu 8/13

11:15 am-10:07 pm

2 stops16h 52m

$757

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Tue 8/25

7:45 pm-7:35 pm

2 stops17h 50m

Václav Havel Prague

Sat 12/12

8:55 am-6:16 pm

2 stops15h 21m

$777

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Sun 9/6

8:27 pm-9:00 am

1 stop30h 33m

Václav Havel Prague

Sun 9/13

11:00 am-10:23 pm

1 stop17h 23m

$805

SavannahPrague

SAV - PRG

SAVPRG

Savannah/Hilton Head

Sun 12/6

3:00 pm-5:55 pm

2 stops20h 55m

Václav Havel Prague

Thu 12/10

7:15 am-9:10 pm

2 stops19h 55m

$812

ColumbiaPrague

CAE - PRG

CAEPRG

Columbia Metropolitan

Sun 11/1

10:20 am-4:05 pm

2 stops23h 45m

Václav Havel Prague

Thu 11/5

11:30 am-9:47 am

2 stops28h 17m

$812

ColumbiaPrague

CAE - PRG

CAEPRG

Columbia Metropolitan

Sun 11/1

7:35 pm-10:25 pm

2 stops20h 50m

Václav Havel Prague

Wed 11/4

7:15 am-9:16 pm

2 stops20h 01m

$812

SavannahPrague

SAV - PRG

SAVPRG

Savannah/Hilton Head

Sat 9/12

3:23 pm-10:50 am

2 stops37h 27m

Václav Havel Prague

Wed 9/16

12:30 pm-3:04 pm

2 stops32h 34m

$834

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Sat 8/1

7:00 am-10:50 am

2 stops45h 50m

Václav Havel Prague

Sat 8/15

6:00 am-9:10 pm

2 stops21h 10m

$844

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/14

Showing 1-10 of 43 resultsSorted by cheapest first
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Best time to book a flight from South Carolina to Prague

Have a flexible travel schedule? Discover the best time to fly to Prague from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Prague

How much does it cost to fly round-trip from South Carolina to Prague?

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Prague. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Prague from South Carolina?

    Most people fly into Václav Havel Prague (PRG) if they book a flight to Prague from South Carolina. Václav Havel Prague is conveniently located just 6.9 mi from Prague’s city center.

  • How long is the flight from South Carolina to Prague?

    There are many flights that can get you from South Carolina to Prague in 11h. Fly via American Airlines, KLM, or Delta to get the fastest option. South Carolina and Prague are separated by a distance of 4608 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from South Carolina to Prague?

  • Can I find deals for flights from South Carolina to Prague that include hotel bookings?

    Yes. In addition to deals on South Carolina to Prague flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Prague?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Prague.

  • Can I find deals for business class flights from South Carolina to Prague?

    Yes. Cheapflights offers flight deals from South Carolina to Prague by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from South Carolina to Prague

Discover the top airline that operate flights from South Carolina to Prague. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 15, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$485Average$485FlexibilityNo cancel feeOn-time71%

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