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Prague

$296+ Cheap flights from South Carolina to Prague (PRG)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/5. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — PRG
Mar 21 — Mar 281
Sat 3/21
Sat 3/28
1 adult, Economy
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Cheap flight deals from South Carolina to Prague

Cheapest flights from South Carolina to Prague
Explore the most affordable flight options available from South Carolina to Prague. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 19, 2026.

This CrystalTravel deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CrystalTravel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:50 pm
CLT
-
PRG
1 stop15h 15m
Lufthansa
Thu 11/56:15 am
PRG
-
CLT
1 stop16h 40m
Lufthansa
Deal found 2/17$503
This AirNGo deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure AirNGo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:00 pm
CLT
-
PRG
2 stops34h 45m
Air Canada
Mon 11/21:45 pm
PRG
-
CLT
2 stops37h 14m
Air Canada
Deal found 2/17$509
This CrystalTravel deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CrystalTravel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:50 pm
CLT
-
PRG
1 stop15h 15m
Lufthansa
Fri 11/63:10 pm
PRG
-
CLT
2 stops15h 35m
Lufthansa
Deal found 2/17$511
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:00 pm
CLT
-
PRG
1 stop13h 15m
American Airlines
Wed 8/1910:15 am
PRG
-
CLT
2 stops15h 30m
American Airlines
Deal found 2/18$513
This AirNGo deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure AirNGo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/289:20 am
CLT
-
PRG
2 stops25h 45m
Multiple Airlines
Mon 11/21:45 pm
PRG
-
CLT
1 stop33h 10m
Multiple Airlines
Deal found 2/17$515
This FlightHub deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:40 pm
CLT
-
PRG
1 stop20h 40m
Lufthansa
Wed 8/196:15 am
PRG
-
CLT
1 stop16h 30m
Lufthansa
Deal found 2/18$517
This American Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:25 pm
CLT
-
PRG
1 stop17h 05m
American Airlines
Fri 11/66:00 am
PRG
-
CLT
1 stop14h 20m
American Airlines
Deal found 2/17$518
This CrystalTravel deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CrystalTravel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:50 pm
CLT
-
PRG
1 stop12h 15m
Multiple Airlines
Thu 11/56:45 am
PRG
-
CLT
2 stops16h 10m
Multiple Airlines
Deal found 2/17$523
This Delta deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:59 pm
CLT
-
PRG
2 stops16h 06m
Delta
Fri 12/116:00 am
PRG
-
CLT
2 stops18h 16m
Delta
Deal found 2/17$530
This Kiwi.com deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:40 pm
CLT
-
PRG
1 stop12h 05m
Lufthansa
Tue 4/216:15 am
PRG
-
CLT
1 stop16h 30m
Lufthansa
Deal found 2/15$531
This United Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/197:20 pm
SAV
-
PRG
2 stops15h 45m
United Airlines
Thu 3/266:50 am
PRG
-
SAV
2 stops17h 23m
United Airlines
Deal found 2/17$612
This United Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/197:47 pm
CHS
-
PRG
2 stops21h 38m
United Airlines
Thu 3/267:35 am
PRG
-
CHS
2 stops31h 29m
United Airlines
Deal found 2/17$636

Find flight deals from South Carolina to Prague

Keep the following information in mind while searching for South Carolina to Prague flight deals. Data was last updated February 19, 2026.

Round-trip from

$513
(American Airlines)

One-way from

$296
(Kiwi.com)
From South Carolina to Václav Havel Prague
Search Deals
One-way flight from South Carolina to Václav Havel Prague
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Prague that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 19, 2026.
Use the filters below to find and compare flights from South Carolina to Prague that are best for you.

Fly from

South Carolina

Fly to

Prague

Route

Depart

Return

Price

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Wed 8/12

6:40 pm-9:20 pm

1 stop20h 40m

Václav Havel Prague

Wed 8/19

6:15 am-4:45 pm

1 stop16h 30m

$517

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Wed 4/1

6:26 pm-8:50 pm

2 stops20h 24m

Václav Havel Prague

Wed 4/8

6:30 am-4:47 pm

2 stops16h 17m

$572

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Sun 4/19

7:40 pm-9:20 pm

2 stops19h 40m

Václav Havel Prague

Thu 5/7

6:15 am-4:45 pm

1 stop16h 30m

$577

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Wed 4/1

10:13 am-9:20 pm

2 stops29h 07m

Václav Havel Prague

Wed 4/8

6:15 am-4:45 pm

1 stop16h 30m

$578

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Wed 4/1

10:13 am-9:20 pm

2 stops29h 07m

Václav Havel Prague

Mon 4/6

1:25 pm-4:45 pm

1 stop33h 20m

$588

SavannahPrague

SAV - PRG

SAVPRG

Savannah/Hilton Head

Thu 3/19

7:20 pm-4:05 pm

2 stops15h 45m

Václav Havel Prague

Thu 3/26

6:50 am-7:13 pm

2 stops17h 23m

$612

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Sun 8/2

8:05 am-10:50 am

2 stops20h 45m

Václav Havel Prague

Fri 8/14

6:15 am-11:34 pm

2 stops23h 19m

$635

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Fri 4/10

6:00 am-11:00 am

2 stops23h 00m

Václav Havel Prague

Fri 4/24

6:00 am-4:20 pm

2 stops16h 20m

$635

CharlestonPrague

CHS - PRG

CHSPRG

Charleston

Thu 3/19

7:47 pm-10:25 pm

2 stops21h 38m

Václav Havel Prague

Thu 3/26

7:35 am-10:04 am

2 stops31h 29m

$636

AugustaPrague

AGS - PRG

AGSPRG

Augusta Bush Field

Tue 4/7

7:34 pm-11:25 pm

2 stops21h 51m

Václav Havel Prague

Tue 4/14

8:40 am-10:44 pm

2 stops20h 04m

$638

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/18

Showing 1-10 of 47 results
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Best time to book a flight from South Carolina to Prague

Have a flexible travel schedule? Discover the best time to fly to Prague from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Prague

What is the cheapest month to book a flight from South Carolina to Prague?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Prague (average of $506). Flying from South Carolina to Prague in June is currently the most expensive (average of $1,057). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Prague. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Prague from South Carolina?

    Most people fly into Václav Havel Prague (PRG) if they book a flight to Prague from South Carolina. Václav Havel Prague is conveniently located just 6.9 mi from Prague’s city center.

  • How long is the flight from South Carolina to Prague?

    There are many flights that can get you from South Carolina to Prague in 19h 40m. Fly via Lufthansa, British Airways, or United Airlines to get the fastest option. South Carolina and Prague are separated by a distance of 4608 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from South Carolina to Prague?

    The most popular route from South Carolina to Prague is Charlotte Douglas - Václav Havel Prague. You may also consider Charleston - Václav Havel Prague or Columbia Metropolitan - Václav Havel Prague.

  • Can I find deals for flights from South Carolina to Prague that include hotel bookings?

    Yes. In addition to deals on South Carolina to Prague flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Prague?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Prague.

  • Can I find deals for business class flights from South Carolina to Prague?

    Yes. Cheapflights offers flight deals from South Carolina to Prague by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Prague?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Prague (average of $506). Flying from South Carolina to Prague in June is currently the most expensive (average of $1,057). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 3 airlines flying from South Carolina to Prague

Discover the top 3 airlines that operate flights from South Carolina to Prague. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 19, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$485Average$485FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$693Average$906FlexibilityNo cancel feeOn-time69%
DeltaCheapest$735Average$1,104FlexibilityNo cancel feeOn-timeN/A

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