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$329+ Cheap flights from South Carolina to Prague (PRG)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/23. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — PRG
Jun 4 — Jun 111
Thu 6/4
Thu 6/11
1 adult, Economy
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Cheap flight deals from South Carolina to Prague

Cheapest flights from South Carolina to Prague
Explore the most affordable flight options available from South Carolina to Prague. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 5, 2026.

This CrystalTravel deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CrystalTravel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:40 pm
CLT
-
PRG
1 stop15h 25m
Lufthansa
Wed 8/199:35 am
PRG
-
CLT
1 stop13h 10m
Lufthansa
Deal found 5/3$712
This CrystalTravel deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CrystalTravel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:50 pm
CLT
-
PRG
1 stop15h 15m
Lufthansa
Tue 11/173:10 pm
PRG
-
CLT
2 stops15h 40m
Lufthansa
Deal found 5/3$720
This United Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:40 pm
CLT
-
PRG
1 stop15h 25m
United Airlines
Wed 8/1912:30 pm
PRG
-
CLT
2 stops31h 20m
United Airlines
Deal found 5/5$724
This Air Canada deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/93:40 pm
CLT
-
PRG
1 stop13h 10m
Air Canada
Wed 8/2612:30 pm
PRG
-
CLT
2 stops35h 14m
Air Canada
Deal found 5/5$725
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/118:15 pm
CLT
-
PRG
1 stop14h 10m
American Airlines
Tue 8/2510:15 am
PRG
-
CLT
1 stop13h 40m
American Airlines
Deal found 5/5$728
This Air Canada deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/87:44 pm
CLT
-
PRG
2 stops33h 06m
Air Canada
Wed 8/2612:30 pm
PRG
-
CLT
2 stops31h 20m
Air Canada
Deal found 5/5$729
This Gotogate deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/43:40 pm
CLT
-
PRG
1 stop13h 10m
Multiple Airlines
Tue 8/184:40 pm
PRG
-
CLT
1 stop30h 05m
Multiple Airlines
Deal found 5/2$732
This Air Canada deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/123:40 pm
CLT
-
PRG
2 stops16h 15m
Air Canada
Wed 8/2612:30 pm
PRG
-
CLT
2 stops31h 48m
Air Canada
Deal found 5/5$734
This Gotogate deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:00 pm
CLT
-
PRG
2 stops15h 20m
Multiple Airlines
Mon 11/161:45 pm
PRG
-
CLT
1 stop33h 10m
Multiple Airlines
Deal found 5/2$735
This KLM deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1210:01 am
CLT
-
PRG
1 stop16h 59m
KLM
Wed 8/1911:00 am
PRG
-
CLT
1 stop13h 51m
KLM
Deal found 5/5$736
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/85:55 pm
CHS
-
PRG
2 stops17h 10m
Delta
Thu 11/126:00 am
PRG
-
CHS
2 stops22h 11m
Delta
Deal found 5/4$811
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/123:25 pm
SAV
-
PRG
3 stops37h 25m
United Airlines
Wed 9/1612:30 pm
PRG
-
SAV
2 stops31h 41m
United Airlines
Deal found 4/30$835

Find flight deals from South Carolina to Prague

Keep the following information in mind while searching for South Carolina to Prague flight deals. Data was last updated May 5, 2026.

Round-trip from

$712
(CrystalTravel)

One-way from

$329
(oojo)
From South Carolina to Václav Havel Prague
Search Deals
One-way flight from South Carolina to Václav Havel Prague
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Prague that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 5, 2026.
Use the filters below to find and compare flights from South Carolina to Prague that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Wed 8/12

6:40 pm-4:05 pm

1 stop15h 25m

Václav Havel Prague

Wed 8/19

12:30 pm-1:50 pm

2 stops31h 20m

$724

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Wed 8/12

10:01 am-9:00 am

1 stop16h 59m

Václav Havel Prague

Wed 8/19

11:00 am-10:58 pm

1 stop17h 58m

$736

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Sat 10/31

8:00 pm-4:05 pm

2 stops39h 05m

Václav Havel Prague

Sat 11/14

6:15 am-4:55 pm

1 stop16h 40m

$803

SavannahPrague

SAV - PRG

SAVPRG

Savannah/Hilton Head

Sat 9/12

3:25 pm-10:50 am

3 stops37h 25m

Václav Havel Prague

Wed 9/16

12:30 pm-2:11 pm

2 stops31h 41m

$835

SavannahPrague

SAV - PRG

SAVPRG

Savannah/Hilton Head

Wed 7/29

7:50 am-9:00 am

1 stop19h 10m

Václav Havel Prague

Thu 8/6

11:00 am-9:51 pm

1 stop16h 51m

$891

CharlestonPrague

CHS - PRG

CHSPRG

Charleston

Wed 9/9

11:08 am-5:55 pm

2 stops24h 47m

Václav Havel Prague

Sat 9/26

12:30 pm-11:59 pm

2 stops41h 29m

$895

CharlottePrague

CLT - PRG

CLTPRG

Charlotte Douglas

Mon 8/31

6:59 pm-9:00 am

1 stop32h 01m

Václav Havel Prague

Mon 9/14

11:00 am-10:23 pm

1 stop17h 23m

$902

GreenvillePrague

GSP - PRG

GSPPRG

Greenville

Thu 8/6

10:45 am-8:55 am

2 stops16h 10m

Václav Havel Prague

Fri 8/14

6:00 am-9:53 pm

2 stops21h 53m

$907

GreenvillePrague

GSP - PRG

GSPPRG

Greenville

Thu 8/6

2:27 pm-8:15 am

1 stop11h 48m

Václav Havel Prague

Fri 8/14

10:15 am-7:45 pm

1 stop15h 30m

$917

GreenvillePrague

GSP - PRG

GSPPRG

Greenville

Thu 8/6

9:09 am-8:15 am

2 stops17h 06m

Václav Havel Prague

Fri 8/14

10:15 am-7:45 pm

1 stop15h 30m

$926

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/5

Showing 1-10 of 52 resultsSorted by cheapest first
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Best time to book a flight from South Carolina to Prague

Have a flexible travel schedule? Discover the best time to fly to Prague from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Prague

How much does it cost to fly round-trip from South Carolina to Prague?

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Prague. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Prague from South Carolina?

    Most people fly into Václav Havel Prague (PRG) if they book a flight to Prague from South Carolina. Václav Havel Prague is conveniently located just 6.9 mi from Prague’s city center.

  • How long is the flight from South Carolina to Prague?

    There are many flights that can get you from South Carolina to Prague in 12h 05m. Fly via United Airlines, KLM, or Delta to get the fastest option. South Carolina and Prague are separated by a distance of 4608 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from South Carolina to Prague?

    The most popular route from South Carolina to Prague is Charlotte Douglas - Václav Havel Prague. You may also consider Greenville - Václav Havel Prague or Columbia Metropolitan - Václav Havel Prague.

  • Can I find deals for flights from South Carolina to Prague that include hotel bookings?

    Yes. In addition to deals on South Carolina to Prague flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Prague?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Prague.

  • Can I find deals for business class flights from South Carolina to Prague?

    Yes. Cheapflights offers flight deals from South Carolina to Prague by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from South Carolina to Prague

Discover the top 2 airlines that operate flights from South Carolina to Prague. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 5, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$485Average$485FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$627Average$840FlexibilityNo cancel feeOn-time69%

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