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$287+ Cheap flights from Jacksonville (JAX) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/18. Fares are subject to change and may not be available on all flights or dates of travel.
JAX — PTY
May 1 — May 81
Fri 5/1
Fri 5/8
1 adult, Economy
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Cheap flight deals from Jacksonville to Panama

Cheapest flights from Jacksonville to Panama
Explore the most affordable flight options available from Jacksonville to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2026.

This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:32 am
JAX
-
PTY
1 stop8h 38m
American Airlines
Tue 9/153:40 pm
PTY
-
JAX
1 stop7h 12m
American Airlines
Deal found 3/31$444
This American Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:50 pm
JAX
-
PTY
2 stops19h 24m
American Airlines
Wed 6/31:14 pm
PTY
-
JAX
1 stop27h 34m
American Airlines
Deal found 3/29$456
This United Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1211:25 am
JAX
-
PTY
1 stop8h 12m
United Airlines
Tue 5/1910:00 am
PTY
-
JAX
1 stop10h 50m
United Airlines
Deal found 3/28$459
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:30 am
JAX
-
PTY
1 stop8h 30m
American Airlines
Mon 10/123:35 pm
PTY
-
JAX
1 stop7h 14m
American Airlines
Deal found 3/31$462
This American Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:42 pm
JAX
-
PTY
2 stops19h 04m
American Airlines
Tue 5/191:49 pm
PTY
-
JAX
2 stops21h 50m
American Airlines
Deal found 3/28$463
This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/105:27 pm
JAX
-
PTY
1 stop26h 10m
United Airlines
Tue 5/197:55 am
PTY
-
JAX
1 stop12h 55m
United Airlines
Deal found 3/30$468
This United Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/276:35 am
JAX
-
PTY
1 stop10h 37m
United Airlines
Mon 5/43:30 pm
PTY
-
JAX
1 stop18h 10m
United Airlines
Deal found 3/28$473
This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/911:25 am
JAX
-
PTY
1 stop8h 12m
United Airlines
Tue 5/197:55 am
PTY
-
JAX
1 stop12h 55m
United Airlines
Deal found 3/30$477
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/93:52 pm
JAX
-
PTY
2 stops21h 54m
American Airlines
Tue 5/191:49 pm
PTY
-
JAX
2 stops18h 14m
American Airlines
Deal found 3/30$481
This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/109:00 am
JAX
-
PTY
1 stop30h 14m
United Airlines
Thu 5/1410:00 am
PTY
-
JAX
1 stop9h 02m
United Airlines
Deal found 3/30$482

Find flight deals from Jacksonville to Panama

Keep the following information in mind while searching for Jacksonville to Panama flight deals. Data was last updated April 1, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$444
(American Airlines)

One-way from

$246
(United Airlines)

Popular in

February

Cheapest in

October

Average price

$512
Provider with most accurate pricing for Jacksonville-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Jacksonville-Panama City Tocumen Intl flights.
Search Deals
From Jacksonville to Panama
Search Deals
One-way flight from Jacksonville to Panama
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($40 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Jacksonville to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2026.
Use the filters below to find and compare flights from Jacksonville to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

JacksonvillePanama City

JAX - PTY

JAXPTY

Jacksonville

Fri 9/11

10:00 am-2:10 pm

1 stop5h 10m

Panama City Tocumen Intl

Tue 9/15

3:40 pm-1:10 pm

2 stops20h 30m

$448

JacksonvillePanama City

JAX - PTY

JAXPTY

Jacksonville

Tue 5/12

11:25 am-6:37 pm

1 stop8h 12m

Panama City Tocumen Intl

Tue 5/19

10:00 am-9:50 pm

1 stop10h 50m

$459

JacksonvillePanama City

JAX - PTY

JAXPTY

Jacksonville

Sat 7/4

7:05 am-4:12 pm

1 stop10h 07m

Panama City Tocumen Intl

Mon 7/6

7:55 am-11:20 pm

1 stop14h 25m

$462

JacksonvillePanama City

JAX - PTY

JAXPTY

Jacksonville

Tue 5/12

6:42 pm-12:46 pm

2 stops19h 04m

Panama City Tocumen Intl

Tue 5/19

1:49 pm-12:39 pm

2 stops21h 50m

$463

JacksonvillePanama City

JAX - PTY

JAXPTY

Jacksonville

Thu 5/14

6:12 pm-12:46 pm

2 stops19h 34m

Panama City Tocumen Intl

Thu 5/21

1:14 pm-8:35 am

2 stops18h 21m

$463

JacksonvillePanama City

JAX - PTY

JAXPTY

Jacksonville

Sun 5/10

9:00 am-2:14 pm

1 stop30h 14m

Panama City Tocumen Intl

Thu 5/14

10:00 am-8:02 pm

1 stop9h 02m

$482

JacksonvillePanama City

JAX - PTY

JAXPTY

Jacksonville

Sat 5/9

5:05 am-12:50 pm

1 stop8h 45m

Panama City Tocumen Intl

Tue 5/19

2:15 pm-12:22 am

1 stop9h 07m

$491
Quickest round-trip

JacksonvillePanama City

JAX - PTY

JAXPTY

Jacksonville

Sat 5/9

5:05 am-12:50 pm

1 stop8h 45m

Panama City Tocumen Intl

Thu 5/14

2:15 pm-10:55 pm

1 stop7h 40m

$491
Cheapest one-way

JacksonvillePanama City

JAX - PTY

JAXPTY

Jacksonville

Thu 6/18

4:14 pm-6:37 pm

1 stop27h 23m

$287
Quickest one-way

JacksonvillePanama City

JAX - PTY

JAXPTY

Jacksonville

Mon 4/6

6:35 am-2:14 pm

1 stop8h 39m

$303

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/28

Showing 1-10 of 11 resultsSorted by cheapest first
1
2

Best time to book a flight from Jacksonville to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Jacksonville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Jacksonville to Panama

What is the cheapest month to book a flight from Jacksonville to Panama?

Currently, October is the cheapest month in which you can book a flight from Jacksonville to Panama (average of $313). Flying from Jacksonville to Panama in November is currently the most expensive (average of $446). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated April 1, 2026.
Read through reviews of airlines operating flights from Jacksonville to Panama, such as Delta,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,368 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.8

Food

7.2

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
8,368 reviews
Delta
7.9
Good
8,368 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.8

Food

7.2

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
United Airlines
7.4
Good
9,529 reviews
Delta
7.9
Good
8,368 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.8

Food

7.2

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.1
Good
11,544 reviews
Delta
7.9
Good
8,368 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.8

Food

7.2

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Jacksonville to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Jacksonville to Panama?

    Located just 11.2 mi from the city center, Jacksonville (JAX) is the airport most travelers will use when flying to Panama from Jacksonville.

  • How long is the flight from Jacksonville to Panama?

    There are many flights that can get you from Jacksonville to Panama in 5h 10m. Fly via United Airlines or American Airlines to get the fastest option. The distance from Jacksonville to Panama is about 1486 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Jacksonville to Panama one-way?

    One-way options have recently been found by users for as low as $105 on Delta. Other airlines that offer cheap prices include American Airlines from $148 and United Airlines from $148 one-way.

  • Can I find deals for flights from Jacksonville to Panama that include hotel bookings?

    Yes. In addition to deals on Jacksonville to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Jacksonville to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jacksonville to Panama.

  • Can I find deals for business class flights from Jacksonville to Panama?

    Yes. Cheapflights offers flight deals from Jacksonville to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Jacksonville to Panama?

    Currently, October is the cheapest month in which you can book a flight from Jacksonville to Panama (average of $313). Flying from Jacksonville to Panama in November is currently the most expensive (average of $446). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Jacksonville to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Tampa to San Pedro Sula flights
West Palm Beach to San Salvador flights
Pensacola to San José flights
Fort Lauderdale to Philip S.W.Goldson flights
Pensacola to Panama City flights
Jacksonville to Liberia flights
Sarasota to San José flights
Jacksonville to San Salvador flights

Top 3 airlines flying from Jacksonville to Panama

Discover the top 3 airlines that operate flights from Jacksonville to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$317Average$591FlexibilityNo cancel feeOn-time71%
DeltaCheapest$317Average$454FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$330Average$484FlexibilityNo cancel feeOn-time69%

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