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$205+ Cheap flights from Fort Myers (RSW) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/23. Fares are subject to change and may not be available on all flights or dates of travel.
RSW — PTY
nov. 29 — dic. 61
sáb. 11/29
sáb. 12/6
1 adult, Economy
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Find flight deals from Fort Myers to Panama

Cheapest flights from Fort Myers to Panama
Explore the most affordable flight options available from Fort Myers to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 30, 2025.

This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/106:21 pmRSW - PTY
2 stops19h 28mAmerican Airlines
jue. 11/132:49 pmPTY - RSW
2 stops21h 32mAmerican Airlines
Deal found 10/30$590
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/131:49 pmRSW - PTY
2 stops25h 53mAmerican Airlines
sáb. 12/204:55 pmPTY - RSW
2 stops20h 05mAmerican Airlines
Deal found 10/30$620
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/145:05 pmRSW - PTY
1 stop24h 02mUnited Airlines
dom. 12/214:41 pmPTY - RSW
1 stop17h 59mUnited Airlines
Deal found 10/30$781
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/137:00 amRSW - PTY
1 stop12h 38mUnited Airlines
sáb. 12/204:41 pmPTY - RSW
1 stop18h 03mUnited Airlines
Deal found 10/30$794
This Mytrip deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/114:30 pmRSW - PTY
3 stops32h 10mMultiple Airlines
lun. 11/242:55 amPTY - RSW
3 stops31h 09mMultiple Airlines
Deal found 10/29$888
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/105:35 amRSW - PTY
1 stop8h 37mDelta
jue. 11/133:37 pmPTY - RSW
1 stop7h 30mDelta
Deal found 10/30$894
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/117:00 amRSW - PTY
1 stop7h 45mUnited Airlines
mar. 11/254:41 pmPTY - RSW
1 stop17h 55mUnited Airlines
Deal found 10/29$1,149
This WestJet deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure WestJet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/1411:45 amRSW - PTY
2 stops45h 35mWestJet
dom. 12/2110:20 amPTY - RSW
2 stops48h 40mWestJet
Deal found 10/30$1,405

Cheap flight deals from Fort Myers to Panama

Keep the following information in mind while searching for Fort Myers to Panama flight deals. Data was last updated octubre 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$480
(American Airlines)

One-way from

$205
(Delta)

Popular in

January

Cheapest in

June
Provider with most accurate pricing for Fort Myers SW Florida Intl-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Fort Myers SW Florida Intl-Panama City Tocumen Intl flights.
Search Deals
From Fort Myers SW Florida Intl to Panama
Search Deals
One-way flight from Fort Myers SW Florida Intl to Panama
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($54 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Fort Myers to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 30, 2025.
Use the filters below to find and compare flights from Fort Myers to Panama that are best for you.

Fly from

Fort Myers

Fly to

Panama

Route

Depart

Return

Price

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

sáb. 1/31

6:35 pm-1:27 pm

2 stops18h 52m

Panama City Tocumen Intl

sáb. 2/7

5:00 pm-10:20 am

2 stops17h 20m

$480

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

dom. 3/22

3:06 pm-12:55 pm

1 stop22h 49m

Panama City Tocumen Intl

mié. 3/25

2:20 pm-3:41 pm

1 stop24h 21m

$517

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

dom. 3/22

3:41 pm-12:10 pm

2 stops21h 29m

Panama City Tocumen Intl

mié. 3/25

3:50 pm-12:55 pm

2 stops20h 05m

$570

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

lun. 11/10

6:21 pm-1:49 pm

2 stops19h 28m

Panama City Tocumen Intl

jue. 11/13

2:49 pm-12:21 pm

2 stops21h 32m

$590

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

jue. 3/12

7:53 pm-12:10 pm

2 stops17h 17m

Panama City Tocumen Intl

lun. 3/16

3:50 pm-4:25 pm

2 stops23h 35m

$610

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

sáb. 12/13

1:49 pm-3:42 pm

2 stops25h 53m

Panama City Tocumen Intl

sáb. 12/20

4:55 pm-1:00 pm

2 stops20h 05m

$620

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

jue. 3/12

5:35 am-12:55 pm

1 stop8h 20m

Panama City Tocumen Intl

lun. 3/16

2:20 pm-12:37 am

1 stop9h 17m

$692

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

lun. 3/23

5:35 am-12:55 pm

1 stop8h 20m

$205

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

lun. 3/23

7:53 pm-2:20 pm

2 stops19h 27m

$205

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

lun. 11/17

5:35 am-2:12 pm

1 stop8h 37m

$225

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 13 results
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Best time to book a flight from Fort Myers to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Fort Myers with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Fort Myers to Panama
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated octubre 30, 2025.
Peruse reviews from past customers who have flown with Delta from Fort Myers to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,998 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
7,998 reviews
Delta
7.9
Good
7,998 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Fort Myers to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Fort Myers to Panama?

    For a flight from Fort Myers to Panama, you will be flying from SW Florida Intl. Fort Myers SW Florida Intl (RSW) is just 10.0 mi from the center of the city.

  • How long is the flight from Fort Myers to Panama?

    American Airlines and Delta can get you from Fort Myers to Panama in just under 18h 52m. Your travel time can differ by up to 3h 57m. The distance between Fort Myers and Panama is about 1216 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Fort Myers to Panama that include hotel bookings?

    Yes. In addition to deals on Fort Myers to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Fort Myers to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Panama.

  • Can I find deals for business class flights from Fort Myers to Panama?

    Yes. Cheapflights offers flight deals from Fort Myers to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Fort Myers to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Fort Myers to Panama

Discover the top airline that operate flights from Fort Myers to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$467Average$515FlexibilityNo cancel feeOn-timeN/A

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