How long is the flight from Fort Myers to Panama?

American Airlines and United Airlines can get you from Fort Myers to Panama in just under 7h 45m. Your travel time can differ by up to 11h 49m. The distance between Fort Myers and Panama is about 1216 mi. Both multi-stop and nonstop flights can be found to your destination and back.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

What is the cheapest time of day to fly from RSW to PA?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Fort Myers to Panama as you normally would.

What airport do you fly from for flights from Fort Myers to Panama?

For a flight from Fort Myers to Panama, you will be flying from SW Florida Intl. Fort Myers SW Florida Intl (RSW) is just 10.0 mi from the center of the city.

Can I find deals for flights from Fort Myers to Panama that include hotel bookings?

Yes. In addition to deals on Fort Myers to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Fort Myers to Panama?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Panama.

Can I find deals for business class flights from Fort Myers to Panama?

Yes. Cheapflights offers flight deals from Fort Myers to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$220+ Flights from Fort Myers to Panama

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Cheap flight deals from Fort Myers to Panama

Cheapest flights from Fort Myers to Panama
Explore the most affordable flight options available from Fort Myers to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Mon 12/298:00 amRSW - PTY

1 stop12h 00mDelta

Sun 1/48:00 amPTY - RSW

1 stop13h 10mDelta

Deal found 12/16

$990

Mon 12/297:40 pmRSW - PTY

2 stops20h 14mAmerican Airlines

Sun 1/42:53 pmPTY - RSW

2 stops18h 44mAmerican Airlines

Deal found 12/16

$1,199

Best flights from Fort Myers to Panama
Discover carefully curated flight deals from Fort Myers to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 18, 2025.

Mon 5/115:41 pmRSW - PTY

2 stops19h 34mAmerican Airlines

Tue 5/191:55 pmPTY - RSW

2 stops19h 45mAmerican Airlines

Deal found 12/17

$440

Sat 2/77:00 amRSW - PTY

1 stop7h 45mUnited Airlines

Mon 2/94:41 pmPTY - RSW

1 stop18h 04mUnited Airlines

Deal found 12/15

$456

Fri 1/306:00 amRSW - PTY

2 stops9h 38mAmerican Airlines

Fri 2/64:50 pmPTY - RSW

2 stops24h 55mAmerican Airlines

Deal found 12/15

$460

Wed 1/2111:48 amRSW - PTY

1 stop7h 50mUnited Airlines

Mon 1/264:41 pmPTY - RSW

1 stop18h 04mUnited Airlines

Deal found 12/16

$476

Sun 3/227:42 pmRSW - PTY

2 stops17h 40mAmerican Airlines

Tue 3/313:13 pmPTY - RSW

2 stops23h 16mAmerican Airlines

Deal found 12/17

$476

Thu 3/126:45 amRSW - PTY

1 stop8h 00mUnited Airlines

Mon 3/163:41 pmPTY - RSW

1 stop18h 01mUnited Airlines

Deal found 12/15

$491

Wed 5/65:41 pmRSW - PTY

2 stops19h 34mAmerican Airlines

Sun 5/101:55 pmPTY - RSW

2 stops25h 29mAmerican Airlines

Deal found 12/16

$482

Sun 3/226:45 amRSW - PTY

1 stop8h 00mUnited Airlines

Tue 3/317:55 amPTY - RSW

1 stop13h 06mUnited Airlines

Deal found 12/17

$496

Fri 1/307:00 amRSW - PTY

1 stop10h 07mUnited Airlines

Fri 2/64:41 pmPTY - RSW

1 stop18h 04mUnited Airlines

Deal found 12/15

$496

Wed 1/216:35 pmRSW - PTY

2 stops21h 03mAmerican Airlines

Mon 1/264:50 pmPTY - RSW

2 stops24h 55mAmerican Airlines

Deal found 12/16

$500

Sat 1/3111:48 amRSW - PTY

1 stop26h 57mUnited Airlines

Tue 2/34:41 pmPTY - RSW

1 stop23h 07mUnited Airlines

Deal found 12/16

$515

Last-minute flights from Fort Myers to Panama
Discover last-minute flight deals from Fort Myers to Panama. Data last updated December 18, 2025 and is based on user searches.

Mon 12/298:00 amRSW - PTY

1 stop12h 00mDelta

Sun 1/48:00 amPTY - RSW

1 stop13h 10mDelta

Deal found 12/16

$990

Fri 1/911:48 amRSW - PTY

1 stop7h 50mUnited Airlines

Mon 1/124:41 pmPTY - RSW

1 stop18h 04mUnited Airlines

Deal found 12/16

$561

Fri 1/91:12 pmRSW - PTY

2 stops24h 15mAmerican Airlines

Mon 1/122:27 pmPTY - RSW

2 stops23h 50mAmerican Airlines

Deal found 12/16

$579

Fri 1/97:25 pmRSW - PTY

2 stops21h 51mMultiple Airlines

Mon 1/127:40 pmPTY - RSW

1 stop15h 21mMultiple Airlines

Deal found 12/16

$904

Wed 1/2111:48 amRSW - PTY

1 stop7h 50mUnited Airlines

Mon 1/264:41 pmPTY - RSW

1 stop18h 04mUnited Airlines

Deal found 12/16

$476

Wed 1/216:35 pmRSW - PTY

2 stops21h 03mAmerican Airlines

Mon 1/264:50 pmPTY - RSW

2 stops24h 55mAmerican Airlines

Deal found 12/16

$500

Fri 1/306:00 amRSW - PTY

2 stops9h 38mAmerican Airlines

Fri 2/64:50 pmPTY - RSW

2 stops24h 55mAmerican Airlines

Deal found 12/15

$460

Fri 1/307:00 amRSW - PTY

1 stop10h 07mUnited Airlines

Fri 2/64:41 pmPTY - RSW

1 stop18h 04mUnited Airlines

Deal found 12/15

$496

Fri 1/302:34 pmRSW - PTY

3 stops28h 21mMultiple Airlines

Fri 2/611:25 amPTY - RSW

3 stops23h 36mMultiple Airlines

Deal found 12/15

$638

Sat 1/3111:48 amRSW - PTY

1 stop26h 57mUnited Airlines

Tue 2/34:41 pmPTY - RSW

1 stop23h 07mUnited Airlines

Deal found 12/16

$515

One-way flights from Fort Myers to Panama
Search for one-way flight options from Fort Myers to Panama. Find affordable one-way fares based on user searches. Data last updated December 18, 2025.

Mon 2/95:02 pmRSW - PTY

1 stop21h 43mUnited Airlines

Deal found 12/17

$220

Mon 2/911:40 amRSW - PTY

2 stops21h 40mWestJet

Deal found 12/17

$1,382

Find flight deals from Fort Myers to Panama

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$436 (United Airlines)
One-way from	$220 (United Airlines)

Provider with most accurate pricing for Fort Myers SW Florida Intl-Panama City Tocumen Intl flight deals.

Search Deals

Provider most trusted by Cheapflights users for Fort Myers SW Florida Intl-Panama City Tocumen Intl flights.

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From Fort Myers SW Florida Intl to Panama

Search Deals

One-way flight from Fort Myers SW Florida Intl to Panama

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

Mon 5/11

5:41 pm-12:15 pm

2 stops19h 34m

Panama City Tocumen Intl

Tue 5/19

1:55 pm-10:40 am

2 stops19h 45m

$440

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

Sat 2/7

7:00 am-2:45 pm

1 stop7h 45m

Panama City Tocumen Intl

Mon 2/9

4:41 pm-10:45 am

1 stop18h 04m

$456

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

Fri 1/30

6:00 am-3:38 pm

2 stops9h 38m

Panama City Tocumen Intl

Fri 2/6

4:50 pm-5:45 pm

2 stops24h 55m

$460

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

Wed 1/21

11:48 am-7:38 pm

1 stop7h 50m

Panama City Tocumen Intl

Mon 1/26

4:41 pm-10:45 am

1 stop18h 04m

$476

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

Sun 3/22

7:42 pm-12:22 pm

2 stops17h 40m

Panama City Tocumen Intl

Tue 3/31

3:13 pm-3:29 pm

2 stops23h 16m

$476

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

Wed 5/6

5:41 pm-12:15 pm

2 stops19h 34m

Panama City Tocumen Intl

Sun 5/10

1:55 pm-4:24 pm

2 stops25h 29m

$482

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

Thu 3/12

6:45 am-1:45 pm

1 stop8h 00m

Panama City Tocumen Intl

Mon 3/16

3:41 pm-10:42 am

1 stop18h 01m

$491

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

Sun 3/22

6:45 am-1:45 pm

1 stop8h 00m

Panama City Tocumen Intl

Tue 3/31

7:55 am-10:01 pm

1 stop13h 06m

$496

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

Fri 1/30

7:00 am-5:07 pm

1 stop10h 07m

Panama City Tocumen Intl

Fri 2/6

4:41 pm-10:45 am

1 stop18h 04m

$496

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

Wed 1/21

6:35 pm-3:38 pm

2 stops21h 03m

Panama City Tocumen Intl

Mon 1/26

4:50 pm-5:45 pm

2 stops24h 55m

$500

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/17

Showing 1-10 of 13 results

Best time to book a flight from Fort Myers to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Fort Myers with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Fort Myers to Panama

No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Panama

Peruse reviews from past customers who have flown with Delta from Fort Myers to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.9

Good

8,005 reviews

Reviews

1 / 20

6.0

Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Delta

7.9

Good

8,005 reviews

Delta

7.9

Good

8,005 reviews

Reviews

1 / 20

6.0

Good

pilar,May 2025

RSW - ATL

Related info for your journey

What airport do you fly from for flights from Fort Myers to Panama?
For a flight from Fort Myers to Panama, you will be flying from SW Florida Intl. Fort Myers SW Florida Intl (RSW) is just 10.0 mi from the center of the city.
How long is the flight from Fort Myers to Panama?
American Airlines and United Airlines can get you from Fort Myers to Panama in just under 7h 45m. Your travel time can differ by up to 11h 49m. The distance between Fort Myers and Panama is about 1216 mi. Both multi-stop and nonstop flights can be found to your destination and back.
Can I find deals for flights from Fort Myers to Panama that include hotel bookings?
Yes. In addition to deals on Fort Myers to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Fort Myers to Panama?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Panama.
Can I find deals for business class flights from Fort Myers to Panama?
Yes. Cheapflights offers flight deals from Fort Myers to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Fort Myers to Panama

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Tampa to Managua flights

Pensacola to Managua flights

Sarasota to San José flights

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Pensacola to San José flights

Panama City to San José flights

Top airline flying from Fort Myers to Panama

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$467	Average$515	FlexibilityNo cancel fee	On-timeN/A

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$220+ Cheap flights from Fort Myers (RSW) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/9. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Fort Myers to Panama with Cheapflights

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Cheap flight deals from Fort Myers to Panama

Cheapest flights from Fort Myers to PanamaExplore the most affordable flight options available from Fort Myers to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Explore the most affordable flight options available from Fort Myers to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Find flight deals from Fort Myers to Panama

Keep the following information in mind while searching for Fort Myers to Panama flight deals. Data was last updated December 18, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Cheapflights Fare Finder

Use the filters below to find and compare flights from Fort Myers to Panama that are best for you.

Best time to book a flight from Fort Myers to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Fort Myers with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Fort Myers to Panama

Reviews of airlines servicing Panama

Peruse reviews from past customers who have flown with Delta from Fort Myers to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Fort Myers to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Fort Myers to Panama?

How long is the flight from Fort Myers to Panama?

Can I find deals for flights from Fort Myers to Panama that include hotel bookings?

How can I find direct flights from Fort Myers to Panama?

Can I find deals for business class flights from Fort Myers to Panama?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Fort Myers to Panama

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Fort Myers to Panama

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Travel Smart

Cheapest flights from Fort Myers to Panama
Explore the most affordable flight options available from Fort Myers to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.