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Panama

$187+ Cheap flights from Fort Myers (RSW) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/18. Fares are subject to change and may not be available on all flights or dates of travel.
RSW — PTY
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Fort Myers to Panama

Cheapest flights from Fort Myers to Panama
Explore the most affordable flight options available from Fort Myers to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:09 am
RSW
-
PTY
1 stop10h 03m
United Airlines
Mon 5/257:55 am
PTY
-
RSW
1 stop13h 03m
United Airlines
Deal found 1/27$477
This KAYAK deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/225:03 pm
RSW
-
PTY
1 stop24h 09m
Copa Airlines
Mon 5/2510:00 am
PTY
-
RSW
1 stop10h 58m
Copa Airlines
Deal found 1/27$489
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/247:00 am
RSW
-
PTY
1 stop12h 38m
United Airlines
Tue 3/34:41 pm
PTY
-
RSW
1 stop18h 01m
United Airlines
Deal found 1/26$497
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/2511:45 am
RSW
-
PTY
1 stop7h 53m
United Airlines
Mon 3/303:30 pm
PTY
-
RSW
1 stop29h 29m
United Airlines
Deal found 1/28$507
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/177:00 am
RSW
-
PTY
1 stop12h 38m
United Airlines
Tue 2/244:41 pm
PTY
-
RSW
1 stop18h 01m
United Airlines
Deal found 1/27$517
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/254:19 pm
RSW
-
PTY
2 stops23h 01m
American Airlines
Sat 3/283:10 pm
PTY
-
RSW
2 stops20h 54m
American Airlines
Deal found 1/28$556
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/185:20 pm
RSW
-
PTY
2 stops20h 20m
American Airlines
Wed 3/113:10 pm
PTY
-
RSW
2 stops20h 54m
American Airlines
Deal found 1/27$591
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/246:00 am
RSW
-
PTY
2 stops26h 40m
Multiple Airlines
Tue 3/310:26 am
PTY
-
RSW
1 stop25h 35m
Multiple Airlines
Deal found 1/26$621
This KAYAK deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/27:00 am
RSW
-
PTY
1 stop7h 45m
Copa Airlines
Mon 2/94:41 pm
PTY
-
RSW
1 stop18h 04m
Copa Airlines
Deal found 1/27$632
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/124:19 pm
RSW
-
PTY
2 stops23h 01m
American Airlines
Mon 3/161:40 pm
PTY
-
RSW
2 stops19h 45m
American Airlines
Deal found 1/28$651
This KAYAK deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/186:23 pm
RSW
-
PTY
2 stops20h 52m
GOL
Wed 2/252:40 pm
PTY
-
RSW
2 stops22h 12m
GOL
Deal found 1/28$656
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/26:35 pm
RSW
-
PTY
2 stops18h 52m
American Airlines
Mon 2/92:27 pm
PTY
-
RSW
2 stops21h 55m
American Airlines
Deal found 1/27$661

Find flight deals from Fort Myers to Panama

Keep the following information in mind while searching for Fort Myers to Panama flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$477
(United Airlines)

One-way from

$187
(Kiwi.com)
Provider with most accurate pricing for Fort Myers SW Florida Intl-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Fort Myers SW Florida Intl-Panama City Tocumen Intl flights.
Search Deals
From Fort Myers SW Florida Intl to Panama
Search Deals
One-way flight from Fort Myers SW Florida Intl to Panama
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Fort Myers to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Fort Myers to Panama that are best for you.

Fly from

Fort Myers

Fly to

Panama

Route

Depart

Return

Price

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

Wed 3/25

6:45 am-1:45 pm

1 stop8h 00m

Panama City Tocumen Intl

Sat 3/28

3:41 pm-10:44 am

1 stop18h 03m

$477

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

Sat 5/23

7:09 am-4:12 pm

1 stop10h 03m

Panama City Tocumen Intl

Mon 5/25

10:00 am-9:58 pm

1 stop10h 58m

$477

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

Tue 2/24

7:00 am-7:38 pm

1 stop12h 38m

Panama City Tocumen Intl

Tue 3/3

4:41 pm-10:42 am

1 stop18h 01m

$497

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

Wed 3/25

11:45 am-6:38 pm

1 stop7h 53m

Panama City Tocumen Intl

Mon 3/30

3:30 pm-9:59 pm

1 stop29h 29m

$507

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

Tue 2/17

7:00 am-7:38 pm

1 stop12h 38m

Panama City Tocumen Intl

Tue 2/24

4:41 pm-10:42 am

1 stop18h 01m

$517

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

Thu 3/5

6:45 am-5:07 pm

1 stop10h 22m

Panama City Tocumen Intl

Fri 3/13

7:55 am-10:15 pm

1 stop13h 20m

$556

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

Wed 3/25

4:19 pm-2:20 pm

2 stops23h 01m

Panama City Tocumen Intl

Sat 3/28

3:10 pm-1:04 pm

2 stops20h 54m

$556

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

Wed 2/18

5:20 pm-1:40 pm

2 stops20h 20m

Panama City Tocumen Intl

Wed 3/11

3:10 pm-1:04 pm

2 stops20h 54m

$591

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

Tue 2/24

6:00 am-8:40 am

2 stops26h 40m

Panama City Tocumen Intl

Tue 3/3

10:26 am-12:01 pm

1 stop25h 35m

$621

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

Thu 3/12

4:19 pm-2:20 pm

2 stops23h 01m

Panama City Tocumen Intl

Mon 3/16

1:40 pm-10:25 am

2 stops19h 45m

$651

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 17 results
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Best time to book a flight from Fort Myers to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Fort Myers with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Fort Myers to Panama
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated January 29, 2026.
Peruse reviews from past customers who have flown with Delta from Fort Myers to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,128 reviews

Overall

7.9

Entertainment

7.8

Food

7.2

Crew

8.5

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
8,128 reviews
Delta
7.9
Good
8,128 reviews

Overall

7.9

Entertainment

7.8

Food

7.2

Crew

8.5

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Fort Myers to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Fort Myers to Panama?

    For a flight from Fort Myers to Panama, you will be flying from SW Florida Intl. Fort Myers SW Florida Intl (RSW) is just 10.0 mi from the center of the city.

  • How long is the flight from Fort Myers to Panama?

    United Airlines can get you from Fort Myers to Panama in just under 8h. Your travel time can differ by up to . The distance between Fort Myers and Panama is about 1216 mi.

  • Can I find deals for flights from Fort Myers to Panama that include hotel bookings?

    Yes. In addition to deals on Fort Myers to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Fort Myers to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Panama.

  • Can I find deals for business class flights from Fort Myers to Panama?

    Yes. Cheapflights offers flight deals from Fort Myers to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Fort Myers to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Orlando to Coxen Hole flights
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Pensacola to San José flights
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Top airline flying from Fort Myers to Panama

Discover the top airline that operate flights from Fort Myers to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$467Average$526FlexibilityNo cancel feeOn-timeN/A

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