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Panama

$472+ Cheap flights from Fort Myers (RSW) to Panama

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/10. Fares are subject to change and may not be available on all flights or dates of travel.
RSW — PTY
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Fort Myers to Panama

Keep the following information in mind while searching for Fort Myers to Panama flight deals. Data was last updated September 15, 2025.

Round-trip from

$472
(American Airlines)

Popular in

January

Cheapest in

June

Average price

$515
From Fort Myers SW Florida Intl to Panama
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($58 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
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Find flight deals from Fort Myers to Panama

Cheapest flights from Fort Myers to Panama
Explore the most affordable flight options available from Fort Myers to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/102:57 pmRSW - PTY
2 stops22h 52mAmerican Airlines
Thu 11/132:49 pmPTY - RSW
2 stops21h 32mAmerican Airlines
Deal found 9/14$472
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/106:58 amRSW - PTY
1 stop7h 14mDelta
Thu 11/133:37 pmPTY - RSW
1 stop7h 30mDelta
Deal found 9/15$487
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/65:23 pmRSW - PTY
2 stops20h 24mAmerican Airlines
Fri 12/124:37 pmPTY - RSW
2 stops16h 57mAmerican Airlines
Deal found 9/15$492
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/66:58 amRSW - PTY
1 stop7h 23mDelta
Fri 12/123:46 pmPTY - RSW
1 stop8h 51mDelta
Deal found 9/15$507
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/65:23 pmRSW - PTY
2 stops22h 14mAmerican Airlines
Sat 12/132:50 pmPTY - RSW
2 stops22h 09mAmerican Airlines
Deal found 9/15$512
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/66:58 amRSW - PTY
1 stop13h 01mDelta
Sat 12/138:05 amPTY - RSW
1 stop8h 27mDelta
Deal found 9/15$527
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/57:34 pmRSW - PTY
2 stops19h 29mAmerican Airlines
Sun 10/123:15 pmPTY - RSW
2 stops23h 23mAmerican Airlines
Deal found 9/14$577
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/307:00 amRSW - PTY
1 stop12h 38mUnited Airlines
Thu 11/68:55 amPTY - RSW
1 stop14h 20mUnited Airlines
Deal found 9/15$643
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/56:21 pmRSW - PTY
2 stops19h 28mAmerican Airlines
Sun 11/92:49 pmPTY - RSW
2 stops21h 32mAmerican Airlines
Deal found 9/15$662
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/55:35 amRSW - PTY
1 stop8h 20mDelta
Sun 10/122:21 pmPTY - RSW
1 stop9h 18mDelta
Deal found 9/14$752
This Mytrip deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/67:59 pmRSW - PTY
3 stops23h 26mMultiple Airlines
Thu 12/112:55 amPTY - RSW
3 stops32h 51mMultiple Airlines
Deal found 9/15$767
This Mytrip deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/67:59 pmRSW - PTY
3 stops23h 26mMultiple Airlines
Sat 12/139:45 amPTY - RSW
2 stops25h 06mMultiple Airlines
Deal found 9/15$806

Cheapflights Fare Finder

 
Customize your flight search to find flights from Fort Myers to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Fort Myers to Panama that are best for you.

Fly from

Fort Myers

Fly to

Panama

Route

Depart

Return

Price

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

Mon 11/10

2:57 pm-1:49 pm

2 stops22h 52m

Panama City Tocumen Intl

Thu 11/13

2:49 pm-12:21 pm

2 stops21h 32m

$472

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

Mon 11/10

6:58 am-2:12 pm

1 stop7h 14m

Panama City Tocumen Intl

Thu 11/13

3:37 pm-11:07 pm

1 stop7h 30m

$487

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

Sat 12/6

5:23 pm-1:47 pm

2 stops20h 24m

Panama City Tocumen Intl

Fri 12/12

4:37 pm-9:34 am

2 stops16h 57m

$492

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

Sat 12/6

6:58 am-2:21 pm

1 stop7h 23m

Panama City Tocumen Intl

Fri 12/12

3:46 pm-12:37 am

1 stop8h 51m

$507

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

Sat 12/6

5:23 pm-3:37 pm

2 stops22h 14m

Panama City Tocumen Intl

Sat 12/13

2:50 pm-12:59 pm

2 stops22h 09m

$512

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

Sat 12/6

6:58 am-7:59 pm

1 stop13h 01m

Panama City Tocumen Intl

Sat 12/13

8:05 am-4:32 pm

1 stop8h 27m

$527

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

Thu 3/12

7:53 pm-2:20 pm

2 stops19h 27m

Panama City Tocumen Intl

Mon 3/16

3:50 pm-10:49 am

2 stops17h 59m

$622

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

Wed 11/5

6:21 pm-1:49 pm

2 stops19h 28m

Panama City Tocumen Intl

Sun 11/9

2:49 pm-12:21 pm

2 stops21h 32m

$662

Fort MyersPanama City

RSW - PTY

RSWPTY

Fort Myers SW Florida Intl

Thu 3/12

5:35 am-12:55 pm

1 stop8h 20m

Panama City Tocumen Intl

Mon 3/16

2:20 pm-11:04 pm

1 stop7h 44m

$687

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Best time to book a flight from Fort Myers to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Fort Myers with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Fort Myers to Panama

What is the cheapest time of day to fly from RSW to PA?

Find hourly flight availability from Fort Myers to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Fort Myers to Panama as you normally would.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated September 15, 2025.
Peruse reviews from past customers who have flown with Delta from Fort Myers to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,954 reviews

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
8.0
Very good
7,954 reviews
Delta
8.0
Very good
7,954 reviews

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Fort Myers to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Fort Myers to Panama?

    For a flight from Fort Myers to Panama, you will be flying from SW Florida Intl. Fort Myers SW Florida Intl (RSW) is just 10.0 mi from the center of the city.

  • How long is the flight from Fort Myers to Panama?

    American Airlines and Delta can get you from Fort Myers to Panama in just under 7h 14m. Your travel time can differ by up to 15h 38m. The distance between Fort Myers and Panama is about 1216 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Fort Myers to Panama that include hotel bookings?

    Yes. In addition to deals on Fort Myers to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Fort Myers to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Panama.

  • Can I find deals for business class flights from Fort Myers to Panama?

    Yes. Cheapflights offers flight deals from Fort Myers to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Fort Myers to Panama?

    Currently, October is the cheapest month in which you can book a flight from Fort Myers to Panama (average of $478). Flying from Fort Myers to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Fort Myers to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Fort Myers to Panama

Discover the top airline that operate flights from Fort Myers to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$436Average$515FlexibilityNo cancel feeOn-timeN/A

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