$208+ Cheap flights from Denver (DEN) to Panama
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/13. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — PTY
May 17 — May 241
Round-trip
1 adult, Economy
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Cheapest flights from Denver to PanamaExplore the most affordable flight options available from Denver to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2026.
Explore the most affordable flight options available from Denver to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2026.
This Copa Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/310:43 pm
DEN
- PTY
Nonstop5h 50m
Copa Airlines
Wed 8/1912:56 pm
PTY
- DEN
Nonstop6h 24m
Copa Airlines
Deal found 4/13![Copa Airlines logo]()
$449
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/612:59 am
DEN
- PTY
1 stop11h 06m
Delta
Sun 12/203:25 pm
PTY
- DEN
1 stop10h 24m
Delta
Deal found 4/14![Delta logo]()
$454
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1812:59 am
DEN
- PTY
1 stop10h 57m
Delta
Sat 9/262:21 pm
PTY
- DEN
1 stop10h 24m
Delta
Deal found 4/14![Delta logo]()
$464
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/211:05 pm
DEN
- PTY
2 stops14h 10m
Multiple Airlines
Fri 5/89:33 pm
PTY
- DEN
1 stop12h 24m
Multiple Airlines
Deal found 4/12![Multiple Airlines logo]()
$468
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/511:45 pm
DEN
- PTY
2 stops13h 30m
Multiple Airlines
Fri 5/89:33 pm
PTY
- DEN
1 stop12h 24m
Multiple Airlines
Deal found 4/12![Multiple Airlines logo]()
$474
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/911:45 pm
DEN
- PTY
2 stops13h 30m
Multiple Airlines
Wed 5/139:33 pm
PTY
- DEN
1 stop12h 24m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$486
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/111:40 pm
DEN
- PTY
1 stop31h 50m
Multiple Airlines
Tue 6/93:10 pm
PTY
- DEN
2 stops18h 27m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$498
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1211:45 pm
DEN
- PTY
2 stops13h 30m
Multiple Airlines
Tue 5/199:33 pm
PTY
- DEN
1 stop12h 24m
Multiple Airlines
Deal found 4/12![Multiple Airlines logo]()
$510
Best flights from Denver to PanamaDiscover carefully curated flight deals from Denver to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 17, 2026.
Discover carefully curated flight deals from Denver to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 17, 2026.
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2012:59 am
DEN
- PTY
1 stop10h 57m
Delta
Thu 10/222:21 pm
PTY
- DEN
1 stop10h 28m
Delta
Deal found 4/14![Delta logo]()
$464
This Copa Airlines deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/310:43 pm
DEN
- PTY
Nonstop5h 50m
Copa Airlines
Wed 8/1912:56 pm
PTY
- DEN
Nonstop6h 24m
Copa Airlines
Deal found 4/12![Copa Airlines logo]()
$597
This United Airlines deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/279:10 pm
DEN
- PTY
1 stop18h 02m
United Airlines
Mon 8/33:30 pm
PTY
- DEN
1 stop17h 32m
United Airlines
Deal found 4/12![United Airlines logo]()
$612
This Copa Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/2310:43 pm
DEN
- PTY
Nonstop5h 50m
Copa Airlines
Tue 7/2812:56 pm
PTY
- DEN
Nonstop6h 24m
Copa Airlines
Deal found 4/14![Copa Airlines logo]()
$597
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/265:00 am
DEN
- PTY
1 stop12h 37m
United Airlines
Mon 8/33:30 pm
PTY
- DEN
1 stop9h 27m
United Airlines
Deal found 4/16![United Airlines logo]()
$612
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/1312:59 am
DEN
- PTY
1 stop10h 57m
Delta
Tue 9/222:21 pm
PTY
- DEN
1 stop10h 24m
Delta
Deal found 4/17![Delta logo]()
$612
This Copa Airlines deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/210:43 pm
DEN
- PTY
Nonstop5h 50m
Copa Airlines
Thu 7/912:56 pm
PTY
- DEN
Nonstop6h 24m
Copa Airlines
Deal found 4/12![Copa Airlines logo]()
$607
This United Airlines deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/228:28 pm
DEN
- PTY
1 stop16h 46m
United Airlines
Tue 6/303:30 pm
PTY
- DEN
1 stop17h 32m
United Airlines
Deal found 4/12![United Airlines logo]()
$622
This Copa Airlines deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1010:43 pm
DEN
- PTY
Nonstop5h 50m
Copa Airlines
Sun 9/1312:56 pm
PTY
- DEN
Nonstop6h 15m
Copa Airlines
Deal found 4/12![Copa Airlines logo]()
$612
This Copa Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1510:43 pm
DEN
- PTY
Nonstop5h 50m
Copa Airlines
Sat 9/512:56 pm
PTY
- DEN
Nonstop6h 15m
Copa Airlines
Deal found 4/13![Copa Airlines logo]()
$627
This Copa Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2110:51 pm
DEN
- PTY
Nonstop5h 42m
Copa Airlines
Thu 6/1812:56 pm
PTY
- DEN
Nonstop6h 29m
Copa Airlines
Deal found 4/14![Copa Airlines logo]()
$628
Last-minute flights from Denver to PanamaDiscover last-minute flight deals from Denver to Panama. Data last updated April 17, 2026 and is based on user searches.
Discover last-minute flight deals from Denver to Panama. Data last updated April 17, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2811:05 pm
DEN
- PTY
2 stops14h 10m
Multiple Airlines
Mon 5/43:41 pm
PTY
- DEN
1 stop18h 16m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$556
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3011:05 pm
DEN
- PTY
2 stops14h 10m
Multiple Airlines
Mon 5/46:34 pm
PTY
- DEN
1 stop15h 23m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$578
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/211:05 pm
DEN
- PTY
2 stops14h 10m
Multiple Airlines
Fri 5/89:33 pm
PTY
- DEN
1 stop12h 24m
Multiple Airlines
Deal found 4/12![Multiple Airlines logo]()
$468
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/511:45 pm
DEN
- PTY
2 stops13h 30m
Multiple Airlines
Fri 5/89:33 pm
PTY
- DEN
1 stop12h 24m
Multiple Airlines
Deal found 4/12![Multiple Airlines logo]()
$474
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/611:45 pm
DEN
- PTY
2 stops13h 30m
Multiple Airlines
Wed 5/206:34 pm
PTY
- DEN
1 stop15h 23m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$573
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/911:45 pm
DEN
- PTY
2 stops13h 30m
Multiple Airlines
Wed 5/139:33 pm
PTY
- DEN
1 stop12h 24m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$486
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1111:45 pm
DEN
- PTY
3 stops25h 10m
Multiple Airlines
Mon 5/189:33 pm
PTY
- DEN
1 stop12h 24m
Multiple Airlines
Deal found 4/13![Multiple Airlines logo]()
$581
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1211:45 pm
DEN
- PTY
2 stops13h 30m
Multiple Airlines
Tue 5/199:33 pm
PTY
- DEN
1 stop12h 24m
Multiple Airlines
Deal found 4/12![Multiple Airlines logo]()
$510
This Copa Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1610:51 pm
DEN
- PTY
Nonstop5h 42m
Copa Airlines
Thu 5/2112:56 pm
PTY
- DEN
Nonstop6h 29m
Copa Airlines
Deal found 4/16![Copa Airlines logo]()
$628
This United Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/309:10 pm
DEN
- PTY
1 stop18h 02m
United Airlines
Sun 6/73:30 pm
PTY
- DEN
1 stop9h 27m
United Airlines
Deal found 4/13![United Airlines logo]()
$633
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/311:53 pm
DEN
- PTY
2 stops18h 22m
Multiple Airlines
Tue 6/99:33 pm
PTY
- DEN
1 stop12h 04m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$622
One-way flights from Denver to PanamaSearch for one-way flight options from Denver to Panama. Find affordable one-way fares based on user searches. Data last updated April 17, 2026.
Search for one-way flight options from Denver to Panama. Find affordable one-way fares based on user searches. Data last updated April 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1311:45 pm
DEN
- PTY
2 stops13h 30m
Multiple Airlines
Deal found 4/13![Multiple Airlines logo]()
$208
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1211:45 pm
DEN
- PTY
2 stops13h 30m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/911:40 pm
DEN
- PTY
1 stop13h 50m
Multiple Airlines
Deal found 4/16![Multiple Airlines logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/610:00 am
DEN
- PTY
3 stops22h 15m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$241
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/312:50 pm
DEN
- PTY
3 stops24h 25m
Multiple Airlines
Deal found 4/15![Multiple Airlines logo]()
$253
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/111:59 pm
DEN
- PTY
3 stops37h 16m
Multiple Airlines
Deal found 4/15![Multiple Airlines logo]()
$259
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:30 am
DEN
- PTY
3 stops25h 45m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/245:05 am
DEN
- PTY
3 stops19h 50m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/239:00 pm
DEN
- PTY
3 stops35h 15m
Multiple Airlines
Deal found 4/13![Multiple Airlines logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1211:45 pm
DEN
- PAC
3 stops41h 45m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$624
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/137:20 am
DEN
- PAC
3 stops34h 10m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$704
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/911:49 pm
DEN
- PAC
3 stops41h 41m
Multiple Airlines
Deal found 4/16![Multiple Airlines logo]()
$726
Find flight deals from Denver to Panama
Keep the following information in mind while searching for Denver to Panama flight deals. Data was last updated April 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $449 (Copa Airlines) |
One-way from | $208 (Kiwi.com) |
Popular in | December |
Cheapest in | August |
Average price | $620 |
Good round-trip deal | $525 or less |
Good one-way deal | $235 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Denver to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2026.
Use the filters below to find and compare flights from Denver to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Sun 9/20
12:59 am-12:56 pm
1 stop10h 57m
Panama City Tocumen Intl
Thu 10/22
2:21 pm-11:49 pm
1 stop10h 28m
$464
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Mon 8/3
10:43 pm-5:33 am
Nonstop5h 50m
Panama City Tocumen Intl
Wed 8/19
12:56 pm-6:20 pm
Nonstop6h 24m
$597
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Thu 7/23
10:43 pm-5:33 am
Nonstop5h 50m
Panama City Tocumen Intl
Tue 7/28
12:56 pm-6:20 pm
Nonstop6h 24m
$597
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Thu 7/2
10:43 pm-5:33 am
Nonstop5h 50m
Panama City Tocumen Intl
Thu 7/9
12:56 pm-6:20 pm
Nonstop6h 24m
$607
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Mon 7/27
9:10 pm-4:12 pm
1 stop18h 02m
Panama City Tocumen Intl
Mon 8/3
3:30 pm-8:02 am
1 stop17h 32m
$612
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Sun 7/26
5:00 am-6:37 pm
1 stop12h 37m
Panama City Tocumen Intl
Mon 8/3
3:30 pm-11:57 pm
1 stop9h 27m
$612
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Sun 9/13
12:59 am-12:56 pm
1 stop10h 57m
Panama City Tocumen Intl
Tue 9/22
2:21 pm-11:45 pm
1 stop10h 24m
$612
Quickest round-trip
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Thu 9/10
10:43 pm-5:33 am
Nonstop5h 50m
Panama City Tocumen Intl
Sun 9/13
12:56 pm-6:11 pm
Nonstop6h 15m
$612
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Mon 6/22
8:28 pm-2:14 pm
1 stop16h 46m
Panama City Tocumen Intl
Tue 6/30
3:30 pm-8:02 am
1 stop17h 32m
$622
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Sat 8/15
10:43 pm-5:33 am
Nonstop5h 50m
Panama City Tocumen Intl
Sat 9/5
12:56 pm-6:11 pm
Nonstop6h 15m
$627
Showing 1-10 of 26 resultsSorted by cheapest first
Best time to book a flight from Denver to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from Denver with our price prediction graph.
DEN-PTY
DEN-PAC
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Denver to Panama
DEN-PA0
DEN-PTY
DEN-PAC
What is the cheapest month to book a flight from Denver to Panama?
Currently, March is the cheapest month in which you can book a flight from Denver to Panama (average of $234). Flying from Denver to Panama in June is currently the most expensive (average of $512). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DEN to PA?
Find hourly flight availability from Denver to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Denver to Panama as you normally would.
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated April 17, 2026.
Get a feel of what it's like to fly with Copa Airlines and United Airlines from Denver to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.8
Overall
7.5
Comfort
7.4
Crew
8.1
Entertainment
6.8
Food
6.8
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Boarding
7.8
Overall
7.5
Comfort
7.4
Crew
8.1
Entertainment
6.8
Food
6.8
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Boarding
7.8
Overall
7.5
Comfort
7.4
Crew
8.1
Entertainment
6.8
Food
6.8
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Related info for your journey
Find useful and relevant information for your journey from Denver to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Denver to Panama
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Denver to Panama by cabin class
Find flights from Denver to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Denver and Panama flights
Browse other Denver and Panama flight options. Last updated on April 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Denver to Panama
Discover the top 2 airlines that operate flights from Denver to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$476 | Average$649 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$527 | Average$680 | FlexibilityNo cancel fee | On-time69% |