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$200+ Cheap flights from Denver (DEN) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/19. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — PTY
feb. 28 — mar. 71
sáb. 2/28
sáb. 3/7
1 adult, Economy
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Cheap flight deals from Denver to Panama

Cheapest flights from Denver to Panama
Explore the most affordable flight options available from Denver to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 29, 2026.

This Copa Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/1310:51 pm
DEN
-
PTY
Nonstop5h 42m
Copa Airlines
sáb. 5/2312:56 pm
PTY
-
DEN
Nonstop6h 29m
Copa Airlines
Deal found 1/28$487
This Copa Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/1310:51 pm
DEN
-
PTY
Nonstop5h 42m
Copa Airlines
jue. 4/3012:56 pm
PTY
-
DEN
Nonstop6h 29m
Copa Airlines
Deal found 1/28$497
This Copa Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 5/410:51 pm
DEN
-
PTY
Nonstop5h 42m
Copa Airlines
lun. 5/1112:56 pm
PTY
-
DEN
Nonstop6h 29m
Copa Airlines
Deal found 1/28$502
This Mytrip deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/311:15 am
DEN
-
PTY
2 stops29h 40m
Avianca
lun. 2/97:50 pm
PTY
-
DEN
2 stops24h 34m
Avianca
Deal found 1/28$506
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/282:07 pm
DEN
-
PTY
2 stops21h 29m
American Airlines
dom. 5/31:49 pm
PTY
-
DEN
2 stops24h 28m
American Airlines
Deal found 1/28$511
This Copa Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 4/1010:51 pm
DEN
-
PTY
Nonstop5h 42m
Copa Airlines
sáb. 4/1812:56 pm
PTY
-
DEN
Nonstop6h 29m
Copa Airlines
Deal found 1/28$512
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 2/2811:25 pm
DEN
-
PTY
1 stop9h 15m
Multiple Airlines
mié. 3/119:45 am
PTY
-
DEN
2 stops28h 07m
Multiple Airlines
Deal found 1/28$514
This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/1511:30 pm
DEN
-
PTY
1 stop12h 06m
American Airlines
mié. 4/221:49 pm
PTY
-
DEN
2 stops21h 50m
American Airlines
Deal found 1/29$516
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 2/284:03 pm
DEN
-
PTY
2 stops19h 37m
American Airlines
jue. 4/301:49 pm
PTY
-
DEN
2 stops19h 37m
American Airlines
Deal found 1/28$522
This Copa Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/910:51 pm
DEN
-
PTY
Nonstop5h 42m
Copa Airlines
lun. 4/1312:56 pm
PTY
-
DEN
Nonstop6h 29m
Copa Airlines
Deal found 1/28$527
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 2/2311:59 pm
DEN
-
PTY
1 stop17h 21m
Multiple Airlines
sáb. 3/79:45 am
PTY
-
DEN
2 stops15h 25m
Multiple Airlines
Deal found 1/27$530
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 2/2811:25 pm
DEN
-
PTY
1 stop14h 41m
Multiple Airlines
sáb. 3/73:55 am
PTY
-
DEN
2 stops20h 18m
Multiple Airlines
Deal found 1/28$531

Find flight deals from Denver to Panama

Keep the following information in mind while searching for Denver to Panama flight deals. Data was last updated enero 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$487
(Copa Airlines)

One-way from

$200
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$630

Good round-trip deal

$410 or less

Good one-way deal

$273 or less
Provider with most accurate pricing for Denver Intl-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Denver Intl-Panama City Tocumen Intl flights.
Search Deals
From Denver Intl to Panama
Search Deals
One-way flight from Denver Intl to Panama
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($51 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals
Price to beat on a round-trip flight from Denver Intl to Panama.
Search Deals
Price to beat on a one-way flight from Denver Intl to Panama.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Denver to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 29, 2026.
Use the filters below to find and compare flights from Denver to Panama that are best for you.

Fly from

Denver

Fly to

Panama

Route

Depart

Return

Price

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

mié. 5/13

10:51 pm-5:33 am

Nonstop5h 42m

Panama City Tocumen Intl

sáb. 5/23

12:56 pm-6:25 pm

Nonstop6h 29m

$487

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

mié. 4/15

10:51 pm-5:33 am

Nonstop5h 42m

Panama City Tocumen Intl

mié. 4/22

12:56 pm-6:25 pm

Nonstop6h 29m

$497

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

mié. 5/27

10:51 pm-5:33 am

Nonstop5h 42m

Panama City Tocumen Intl

dom. 5/31

12:56 pm-6:25 pm

Nonstop6h 29m

$502

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

lun. 5/4

10:51 pm-5:33 am

Nonstop5h 42m

Panama City Tocumen Intl

lun. 5/11

12:56 pm-6:25 pm

Nonstop6h 29m

$502

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

vie. 4/17

10:51 pm-5:33 am

Nonstop5h 42m

Panama City Tocumen Intl

dom. 4/26

12:56 pm-6:25 pm

Nonstop6h 29m

$527

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

jue. 3/5

11:25 pm-4:06 pm

1 stop14h 41m

Panama City Tocumen Intl

lun. 3/9

5:50 pm-8:26 am

2 stops15h 36m

$562

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

mar. 3/3

5:58 pm-2:55 pm

3 stops18h 57m

Panama City Tocumen Intl

vie. 3/13

7:50 pm-6:20 pm

2 stops23h 30m

$562

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

mié. 3/4

6:49 pm-10:30 am

2 stops13h 41m

Panama City Tocumen Intl

vie. 3/13

10:25 am-10:55 pm

1 stop13h 30m

$585

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

lun. 4/20

10:51 pm-5:33 am

Nonstop5h 42m

Panama City Tocumen Intl

vie. 5/1

12:56 pm-6:25 pm

Nonstop6h 29m

$589

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

mié. 3/18

10:48 pm-5:33 am

Nonstop5h 45m

Panama City Tocumen Intl

mar. 3/24

12:56 pm-6:16 pm

Nonstop6h 20m

$589

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Showing 1-10 of 21 results
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Best time to book a flight from Denver to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to Panama

What is the cheapest month to book a flight from Denver to Panama?

Currently, March is the cheapest month in which you can book a flight from Denver to Panama (average of $354). Flying from Denver to Panama in June is currently the most expensive (average of $520). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to PA?

Find hourly flight availability from Denver to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated enero 29, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Denver to Panama as you normally would.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated enero 29, 2026.
Get a feel of what it's like to fly with Copa Airlines, United Airlines, and American Airlines from Denver to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,560 reviews

Food

6.8

Boarding

7.8

Comfort

7.4

Crew

8.1

Entertainment

6.8

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Juan,Dec 2025

EZE - PTY

The outbound flight from Boston was awful. The handicapped services were the worst i have ever seen. NEVER AGAIN. THIS WAS NOT WORTH ANYWHERE NEAR $4K.
Copa Airlines
7.5
Good
1,560 reviews
Copa Airlines
7.5
Good
1,560 reviews

Food

6.8

Boarding

7.8

Comfort

7.4

Crew

8.1

Entertainment

6.8

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Juan,Dec 2025

EZE - PTY

The outbound flight from Boston was awful. The handicapped services were the worst i have ever seen. NEVER AGAIN. THIS WAS NOT WORTH ANYWHERE NEAR $4K.
United Airlines
7.4
Good
9,215 reviews
Copa Airlines
7.5
Good
1,560 reviews

Food

6.8

Boarding

7.8

Comfort

7.4

Crew

8.1

Entertainment

6.8

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Juan,Dec 2025

EZE - PTY

The outbound flight from Boston was awful. The handicapped services were the worst i have ever seen. NEVER AGAIN. THIS WAS NOT WORTH ANYWHERE NEAR $4K.
American Airlines
7.2
Good
11,206 reviews
Copa Airlines
7.5
Good
1,560 reviews

Food

6.8

Boarding

7.8

Comfort

7.4

Crew

8.1

Entertainment

6.8

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Juan,Dec 2025

EZE - PTY

The outbound flight from Boston was awful. The handicapped services were the worst i have ever seen. NEVER AGAIN. THIS WAS NOT WORTH ANYWHERE NEAR $4K.

Related info for your journey

Find useful and relevant information for your journey from Denver to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Denver to Panama?

    If you book a flight to Panama from Denver, you will be flying from Denver Intl, which is the city’s only airport. Denver Intl (DEN) is located 18.5 mi from the center of Denver.

  • How popular is this Denver to Panama flight route?

    Within the past month, 30 users have taken a look at flights from Denver Intl to Panama.

  • How long is the flight from Denver to Panama?

    Departing from Denver to Panama will take you 5h 42m. The distance from Denver to Panama is about 2634 mi. Most flights are nonstop.

  • What are the cheapest flights from Denver to Panama?

    Looking at all options, your cheapest flight can be booked for $173. While the most popular route (Denver Intl - Panama City Tocumen Intl) can be booked for $548 on average, our data indicates $715 when flying from Denver to Panama.

  • Can I find deals for flights from Denver to Panama that include hotel bookings?

    Yes. In addition to deals on Denver to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Panama.

  • Can I find deals for business class flights from Denver to Panama?

    Yes. Cheapflights offers flight deals from Denver to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to Panama?

    Currently, March is the cheapest month in which you can book a flight from Denver to Panama (average of $354). Flying from Denver to Panama in June is currently the most expensive (average of $520). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Denver to Panama

See prices for flight routes from nearby airports that may be better suited for you.
Denver to Liberia flights
Denver to San José flights
Denver to Philip S.W.Goldson flights
Denver to Panama City flights
Denver to Guatemala City flights
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Denver to Managua flights
Denver to Coxen Hole flights
Denver to San Pedro Sula flights
Vail to Liberia flights
Grand Junction to Liberia flights
Colorado Springs to Philip S.W.Goldson flights
Durango to San José flights
Colorado Springs to Liberia flights
Montrose to San José flights
Montrose to Liberia flights
Colorado Springs to San José flights
Colorado Springs to Panama City flights
Grand Junction to San José flights
Aspen to San José flights
Aspen to San Salvador flights
Durango to Philip S.W.Goldson flights
Colorado Springs to Managua flights
Grand Junction to Guatemala City flights
Gunnison to Liberia flights
Montrose to San Salvador flights
Montrose to Managua flights
Vail to San Salvador flights
Montrose to Philip S.W.Goldson flights
Gunnison to San Salvador flights
Grand Junction to Managua flights
Denver to Tegucigalpa flights
Cortez to San José flights
Colorado Springs to Guatemala City flights
Durango to Managua flights
Vail to San José flights
Denver to San Pedro Town flights
Durango to Coxen Hole flights

Top 3 airlines flying from Denver to Panama

Discover the top 3 airlines that operate flights from Denver to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$469Average$627FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$473Average$642FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$527Average$683FlexibilityNo cancel feeOn-time69%

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