HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama

$194+ Cheap flights from Denver (DEN) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/18. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — PTY
Apr 17 — Apr 241
Fri 4/17
Fri 4/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Denver to Panama with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Denver to Panama

Cheapest flights from Denver to Panama
Explore the most affordable flight options available from Denver to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 18, 2026.

This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2811:05 pm
DEN
-
PTY
1 stop15h 49m
Multiple Airlines
Tue 5/59:33 pm
PTY
-
DEN
1 stop11h 54m
Multiple Airlines
Deal found 3/15$481
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/223:07 pm
DEN
-
PTY
2 stops15h 59m
Multiple Airlines
Tue 4/289:33 pm
PTY
-
DEN
1 stop13h 07m
Multiple Airlines
Deal found 3/17$492
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:59 pm
DEN
-
PTY
2 stops18h 21m
Multiple Airlines
Tue 4/289:33 pm
PTY
-
DEN
1 stop13h 07m
Multiple Airlines
Deal found 3/17$496
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:59 pm
DEN
-
PTY
2 stops18h 21m
Multiple Airlines
Mon 4/279:33 pm
PTY
-
DEN
1 stop13h 07m
Multiple Airlines
Deal found 3/17$501
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2811:05 pm
DEN
-
PTY
1 stop10h 29m
Multiple Airlines
Sat 5/28:10 am
PTY
-
DEN
2 stops15h 19m
Multiple Airlines
Deal found 3/15$514
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1411:05 pm
DEN
-
PTY
1 stop15h 49m
Multiple Airlines
Tue 4/216:34 pm
PTY
-
DEN
1 stop16h 06m
Multiple Airlines
Deal found 3/17$515
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:00 am
DEN
-
PTY
2 stops12h 20m
Multiple Airlines
Mon 4/279:33 pm
PTY
-
DEN
1 stop13h 07m
Multiple Airlines
Deal found 3/15$516
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/911:45 pm
DEN
-
PTY
1 stop15h 09m
Multiple Airlines
Thu 5/219:33 pm
PTY
-
DEN
1 stop11h 54m
Multiple Airlines
Deal found 3/16$517
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/811:49 pm
DEN
-
PTY
1 stop15h 05m
Multiple Airlines
Tue 4/149:33 pm
PTY
-
DEN
1 stop13h 07m
Multiple Airlines
Deal found 3/15$525
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2711:05 pm
DEN
-
PTY
1 stop10h 29m
Multiple Airlines
Tue 5/1210:25 am
PTY
-
DEN
2 stops12h 59m
Multiple Airlines
Deal found 3/15$526

Find flight deals from Denver to Panama

Keep the following information in mind while searching for Denver to Panama flight deals. Data was last updated March 18, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$481
(Kiwi.com)

One-way from

$194
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$675

Good round-trip deal

$465 or less

Good one-way deal

$223 or less
Provider with most accurate pricing for Denver Intl-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Denver Intl-Panama City Tocumen Intl flights.
Search Deals
From Denver Intl to Panama
Search Deals
One-way flight from Denver Intl to Panama
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($49 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals
Price to beat on a round-trip flight from Denver Intl to Panama.
Search Deals
Price to beat on a one-way flight from Denver Intl to Panama.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Denver to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 18, 2026.
Use the filters below to find and compare flights from Denver to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 4/29

10:51 pm-5:33 am

Nonstop5h 42m

Panama City Tocumen Intl

Wed 5/6

12:56 pm-6:25 pm

Nonstop6h 29m

$588

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 6/18

8:28 pm-4:12 pm

1 stop18h 44m

Panama City Tocumen Intl

Tue 6/30

7:55 am-8:14 pm

1 stop13h 19m

$592

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 9/11

5:00 am-6:37 pm

1 stop12h 37m

Panama City Tocumen Intl

Fri 9/25

10:00 am-11:27 pm

1 stop14h 27m

$592

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sun 5/24

7:35 pm-4:12 pm

1 stop19h 37m

Panama City Tocumen Intl

Sat 6/6

10:00 am-8:14 pm

1 stop11h 14m

$593

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 5/20

8:23 pm-2:14 pm

1 stop16h 51m

Panama City Tocumen Intl

Mon 5/25

3:30 pm-11:57 pm

1 stop9h 27m

$602

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 6/10

5:00 am-4:12 pm

1 stop10h 12m

Panama City Tocumen Intl

Sun 6/14

3:30 pm-11:57 pm

1 stop9h 27m

$602

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 6/12

9:10 pm-2:14 pm

1 stop16h 04m

Panama City Tocumen Intl

Wed 6/24

7:55 am-11:57 pm

1 stop17h 02m

$602

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 4/29

9:50 am-6:37 pm

1 stop7h 47m

Panama City Tocumen Intl

Wed 5/6

7:55 am-6:25 pm

1 stop11h 30m

$613

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 5/2

7:45 am-4:12 pm

1 stop7h 27m

Panama City Tocumen Intl

Wed 5/6

7:55 am-8:16 pm

1 stop13h 21m

$613
Cheapest one-way

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Mon 4/6

11:49 pm-9:15 am

2 stops32h 26m

$208

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/18

Showing 1-10 of 24 resultsSorted by cheapest first
1
2
3

Best time to book a flight from Denver to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to Panama

What is the cheapest month to book a flight from Denver to Panama?

Currently, October is the cheapest month in which you can book a flight from Denver to Panama (average of $438). Flying from Denver to Panama in March is currently the most expensive (average of $535). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to PA?

Find hourly flight availability from Denver to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 18, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Denver to Panama as you normally would.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated March 18, 2026.
Get a feel of what it's like to fly with Copa Airlines and United Airlines from Denver to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,571 reviews

Boarding

7.8

Food

6.8

Crew

8.1

Comfort

7.4

Entertainment

6.8

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.
Copa Airlines
7.5
Good
1,571 reviews
Copa Airlines
7.5
Good
1,571 reviews

Boarding

7.8

Food

6.8

Crew

8.1

Comfort

7.4

Entertainment

6.8

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.
United Airlines
7.4
Good
9,434 reviews
Copa Airlines
7.5
Good
1,571 reviews

Boarding

7.8

Food

6.8

Crew

8.1

Comfort

7.4

Entertainment

6.8

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.

Related info for your journey

Find useful and relevant information for your journey from Denver to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Denver to Panama?

    If you book a flight to Panama from Denver, you will be flying from Denver Intl, which is the city’s only airport. Denver Intl (DEN) is located 18.5 mi from the center of Denver.

  • How popular is this Denver to Panama flight route?

    Within the past month, 31 users have taken a look at flights from Denver Intl to Panama.

  • What are the cheapest flights from Denver to Panama?

    Looking at all options, your cheapest flight can be booked for $183. While the most popular route (Denver Intl - Panama City Tocumen Intl) can be booked for $572 on average, our data indicates $801 when flying from Denver to Panama.

  • Can I find deals for flights from Denver to Panama that include hotel bookings?

    Yes. In addition to deals on Denver to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Panama.

  • Can I find deals for business class flights from Denver to Panama?

    Yes. Cheapflights offers flight deals from Denver to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to Panama?

    Currently, October is the cheapest month in which you can book a flight from Denver to Panama (average of $438). Flying from Denver to Panama in March is currently the most expensive (average of $535). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 2 airlines flying from Denver to Panama

Discover the top 2 airlines that operate flights from Denver to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$479Average$618FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$527Average$682FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.