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$183+ Cheap flights from Denver (DEN) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/1. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — PTY
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Denver to Panama

Keep the following information in mind while searching for Denver to Panama flight deals. Data was last updated September 11, 2025.

Round-trip from

$476
(Kiwi.com)

One-way from

$183
(Kiwi.com)

Popular in

December

Cheapest in

October

Average price

$527

Good round-trip deal

$443 or less

Good one-way deal

$187 or less
From Denver Intl to Panama
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One-way flight from Denver Intl to Panama
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Highest demand for flights based on searches. 5% potential increase in price ($35 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($15 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Denver Intl to Panama.
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Price to beat on a one-way flight from Denver Intl to Panama.
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Find flight deals from Denver to Panama

Cheapest flights from Denver to Panama
Explore the most affordable flight options available from Denver to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/36:55 pmDEN - PTY
1 stop12h 16mMultiple Airlines
Sun 10/126:32 pmPTY - DEN
1 stop15h 01mMultiple Airlines
Deal found 9/10$476
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2912:34 amDEN - PTY
1 stop9h 06mMultiple Airlines
Wed 11/59:33 pmPTY - DEN
1 stop13h 00mMultiple Airlines
Deal found 9/10$480
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/246:55 pmDEN - PTY
1 stop12h 16mMultiple Airlines
Fri 9/266:32 pmPTY - DEN
1 stop15h 43mMultiple Airlines
Deal found 9/10$485
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/211:59 pmDEN - PTY
1 stop16h 41mMultiple Airlines
Sat 10/1111:41 amPTY - DEN
1 stop9h 58mMultiple Airlines
Deal found 9/10$492
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/712:59 amDEN - PTY
2 stops18h 38mMultiple Airlines
Wed 10/159:33 pmPTY - DEN
1 stop12h 00mMultiple Airlines
Deal found 9/10$512
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:23 pmDEN - PTY
1 stop17h 32mDelta
Fri 1/163:27 pmPTY - DEN
1 stop9h 22mDelta
Deal found 9/10$539
This Gotogate deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/3010:46 pmDEN - PTY
Nonstop5h 47mCopa Airlines
Wed 11/512:56 pmPTY - DEN
Nonstop6h 21mCopa Airlines
Deal found 9/10$542
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/286:00 amDEN - PTY
1 stop11h 59mDelta
Wed 12/33:46 pmPTY - DEN
1 stop9h 16mDelta
Deal found 9/10$552

Cheapflights Fare Finder

 
Customize your flight search to find flights from Denver to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Denver to Panama that are best for you.

Fly from

Denver

Fly to

Panama

Route

Depart

Return

Price

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 1/16

9:38 pm-5:33 am

Nonstop5h 55m

Panama City Tocumen Intl

Sat 1/31

12:56 pm-5:16 pm

Nonstop6h 20m

$535

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 2/28

9:38 pm-5:33 am

Nonstop5h 55m

Panama City Tocumen Intl

Sun 3/8

12:56 pm-6:16 pm

Nonstop6h 20m

$535

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 3/5

9:48 pm-5:33 am

Nonstop5h 45m

Panama City Tocumen Intl

Mon 3/9

12:56 pm-6:16 pm

Nonstop6h 20m

$535

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 2/20

10:19 pm-6:10 am

Nonstop5h 51m

Panama City Tocumen Intl

Tue 2/24

12:56 pm-5:16 pm

Nonstop6h 20m

$535

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 1/16

7:05 am-8:04 pm

1 stop10h 59m

Panama City Tocumen Intl

Sat 1/24

8:05 am-11:54 pm

1 stop17h 49m

$539

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 1/16

6:05 am-8:04 pm

1 stop11h 59m

Panama City Tocumen Intl

Fri 1/30

3:27 pm-11:54 pm

1 stop10h 27m

$539

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Mon 12/29

6:23 pm-1:55 pm

1 stop17h 32m

Panama City Tocumen Intl

Fri 1/16

3:27 pm-10:49 pm

1 stop9h 22m

$539

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 1/9

6:05 am-8:04 pm

1 stop11h 59m

Panama City Tocumen Intl

Sun 1/18

8:05 am-10:49 pm

1 stop16h 44m

$539

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 11/28

6:00 am-7:59 pm

1 stop11h 59m

Panama City Tocumen Intl

Wed 12/3

3:46 pm-11:02 pm

1 stop9h 16m

$552

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sun 1/18

12:00 pm-2:02 pm

1 stop24h 02m

Panama City Tocumen Intl

Mon 1/26

3:27 pm-6:10 pm

1 stop28h 43m

$562

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 22 results
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Best time to book a flight from Denver to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to Panama

What is the cheapest month to book a flight from Denver to Panama?

Currently, October is the cheapest month in which you can book a flight from Denver to Panama (average of $478). Flying from Denver to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to PA?

Find hourly flight availability from Denver to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Denver to Panama as you normally would.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated September 11, 2025.
Get a feel of what it's like to fly with Delta, Copa Airlines, and United Airlines from Denver to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Copa Airlines
7.6
Good
1,531 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,937 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Denver to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Denver to Panama?

    If you book a flight to Panama from Denver, you will be flying from Denver Intl, which is the city’s only airport. Denver Intl (DEN) is located 18.5 mi from the center of Denver.

  • How popular is this Denver to Panama flight route?

    Within the past month, 36 users have taken a look at flights from Denver Intl to Panama.

  • How long is the flight from Denver to Panama?

    Departing from Denver to Panama will take you 5h 55m. The distance from Denver to Panama is about 2634 mi. Most flights are nonstop.

  • What are the cheapest flights from Denver to Panama?

    Looking at all options, your cheapest flight can be booked for $138. While the most popular route (Denver Intl - Panama City Tocumen Intl) can be booked for $492 on average, our data indicates $729 when flying from Denver to Panama.

  • Can I find deals for flights from Denver to Panama that include hotel bookings?

    Yes. In addition to deals on Denver to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Panama.

  • Can I find deals for business class flights from Denver to Panama?

    Yes. Cheapflights offers flight deals from Denver to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to Panama?

    Currently, October is the cheapest month in which you can book a flight from Denver to Panama (average of $478). Flying from Denver to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Denver to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Colorado Springs to Panama City flights
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Montrose to San José flights
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Montrose to Managua flights
Montrose to Liberia flights
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Gunnison to Liberia flights
Denver to San Pedro Town flights
Montrose to San Salvador flights
Montrose to Philip S.W.Goldson flights
Grand Junction to Managua flights
Gunnison to San Salvador flights
Aspen to San Salvador flights
Denver to Tegucigalpa flights
Aspen to San José flights
Cortez to San José flights
Vail to San Salvador flights
Colorado Springs to Managua flights
Durango to Managua flights

Top 4 airlines flying from Denver to Panama

Discover the top 4 airlines that operate flights from Denver to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$474Average$657FlexibilityNo cancel feeOn-time70%
DeltaCheapest$527Average$825FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$527Average$667FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$527Average$694FlexibilityNo cancel feeOn-time69%

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