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$174+ Cheap flights from Denver (DEN) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/19. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — PTY
Mar 31 — Apr 71
Tue 3/31
Tue 4/7
1 adult, Economy
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Cheap flight deals from Denver to Panama

Cheapest flights from Denver to Panama
Explore the most affordable flight options available from Denver to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 1, 2026.

This Delta deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/312:59 am
DEN
-
PTY
1 stop10h 51m
Delta
Wed 3/112:28 pm
PTY
-
DEN
1 stop10h 41m
Delta
Deal found 2/25$395
This Delta deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/412:59 am
DEN
-
PTY
1 stop10h 51m
Delta
Wed 3/182:28 pm
PTY
-
DEN
1 stop19h 58m
Delta
Deal found 2/26$404
This Kiwi.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/2611:05 pm
DEN
-
PTY
1 stop19h 15m
Multiple Airlines
Wed 5/63:10 pm
PTY
-
DEN
2 stops18h 17m
Multiple Airlines
Deal found 2/27$427
This Kiwi.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/211:05 pm
DEN
-
PTY
2 stops14h 10m
Multiple Airlines
Mon 5/49:33 pm
PTY
-
DEN
1 stop13h 57m
Multiple Airlines
Deal found 2/27$438
This Kiwi.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2911:05 pm
DEN
-
PTY
1 stop19h 15m
Multiple Airlines
Mon 5/43:10 pm
PTY
-
DEN
2 stops20h 20m
Multiple Airlines
Deal found 2/27$443
This Kiwi.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2811:05 pm
DEN
-
PTY
1 stop19h 15m
Multiple Airlines
Wed 5/63:10 pm
PTY
-
DEN
2 stops18h 17m
Multiple Airlines
Deal found 2/27$444
This Kiwi.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2711:05 pm
DEN
-
PTY
1 stop15h 49m
Multiple Airlines
Wed 5/63:10 pm
PTY
-
DEN
2 stops18h 17m
Multiple Airlines
Deal found 2/27$447
This Kiwi.com deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2811:05 pm
DEN
-
PTY
1 stop19h 15m
Multiple Airlines
Fri 5/83:10 pm
PTY
-
DEN
2 stops18h 59m
Multiple Airlines
Deal found 2/28$448
This Kiwi.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2111:05 pm
DEN
-
PTY
1 stop15h 49m
Multiple Airlines
Tue 4/289:33 pm
PTY
-
DEN
1 stop13h 07m
Multiple Airlines
Deal found 2/27$449
This Kiwi.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1911:05 pm
DEN
-
PTY
1 stop19h 15m
Multiple Airlines
Tue 4/2810:25 am
PTY
-
DEN
1 stop24h 15m
Multiple Airlines
Deal found 2/27$453
This Kiwi.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/2611:05 pm
DEN
-
PTY
1 stop10h 29m
Multiple Airlines
Tue 5/53:10 pm
PTY
-
DEN
2 stops20h 20m
Multiple Airlines
Deal found 2/27$454

Find flight deals from Denver to Panama

Keep the following information in mind while searching for Denver to Panama flight deals. Data was last updated March 1, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$395
(Delta)

One-way from

$174
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$683

Good round-trip deal

$448 or less

Good one-way deal

$223 or less
Provider with most accurate pricing for Denver Intl-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Denver Intl-Panama City Tocumen Intl flights.
Search Deals
From Denver Intl to Panama
Search Deals
One-way flight from Denver Intl to Panama
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($46 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals
Price to beat on a round-trip flight from Denver Intl to Panama.
Search Deals
Price to beat on a one-way flight from Denver Intl to Panama.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Denver to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 1, 2026.
Use the filters below to find and compare flights from Denver to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 4/29

10:51 pm-5:33 am

Nonstop5h 42m

Panama City Tocumen Intl

Wed 5/6

12:56 pm-6:25 pm

Nonstop6h 29m

$527

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 5/6

5:10 am-2:14 pm

1 stop8h 04m

Panama City Tocumen Intl

Fri 5/8

7:55 am-8:16 pm

1 stop13h 21m

$542

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 5/16

5:10 am-4:12 pm

1 stop10h 02m

Panama City Tocumen Intl

Sat 5/23

3:30 pm-11:57 pm

1 stop9h 27m

$542

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 4/17

5:00 am-4:12 pm

1 stop10h 12m

Panama City Tocumen Intl

Sun 4/26

7:55 am-11:57 pm

1 stop17h 02m

$542

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 4/9

10:51 pm-5:33 am

Nonstop5h 42m

Panama City Tocumen Intl

Mon 4/13

12:56 pm-6:25 pm

Nonstop6h 29m

$548

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 5/23

9:10 pm-6:37 pm

1 stop20h 27m

Panama City Tocumen Intl

Sun 5/31

3:30 pm-11:57 pm

1 stop9h 27m

$552

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 4/16

7:45 am-4:12 pm

1 stop7h 27m

Panama City Tocumen Intl

Sun 4/26

3:30 pm-8:38 am

1 stop18h 08m

$553

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sun 4/12

9:50 am-6:37 pm

1 stop7h 47m

Panama City Tocumen Intl

Sun 4/19

7:55 am-4:27 pm

1 stop9h 32m

$553

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sun 4/5

5:00 am-4:12 pm

1 stop10h 12m

Panama City Tocumen Intl

Sun 4/19

10:00 am-10:15 pm

1 stop13h 15m

$553

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 5/1

10:51 pm-5:33 am

Nonstop5h 42m

Panama City Tocumen Intl

Sun 5/17

12:56 pm-6:25 pm

Nonstop6h 29m

$557

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/28

Showing 1-10 of 23 resultsSorted by cheapest first
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3

Best time to book a flight from Denver to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to Panama

What is the cheapest month to book a flight from Denver to Panama?

Currently, October is the cheapest month in which you can book a flight from Denver to Panama (average of $442). Flying from Denver to Panama in March is currently the most expensive (average of $526). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to PA?

Find hourly flight availability from Denver to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 1, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Denver to Panama as you normally would.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated March 1, 2026.
Get a feel of what it's like to fly with Copa Airlines, United Airlines, and American Airlines from Denver to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,557 reviews

Comfort

7.4

Overall

7.5

Crew

8.1

Boarding

7.8

Food

6.8

Entertainment

6.8

Reviews

1 / 20
2.0
Mediocre

Juan,Dec 2025

EZE - PTY

The outbound flight from Boston was awful. The handicapped services were the worst i have ever seen. NEVER AGAIN. THIS WAS NOT WORTH ANYWHERE NEAR $4K.
Copa Airlines
7.5
Good
1,557 reviews
Copa Airlines
7.5
Good
1,557 reviews

Comfort

7.4

Overall

7.5

Crew

8.1

Boarding

7.8

Food

6.8

Entertainment

6.8

Reviews

1 / 20
2.0
Mediocre

Juan,Dec 2025

EZE - PTY

The outbound flight from Boston was awful. The handicapped services were the worst i have ever seen. NEVER AGAIN. THIS WAS NOT WORTH ANYWHERE NEAR $4K.
United Airlines
7.4
Good
9,371 reviews
Copa Airlines
7.5
Good
1,557 reviews

Comfort

7.4

Overall

7.5

Crew

8.1

Boarding

7.8

Food

6.8

Entertainment

6.8

Reviews

1 / 20
2.0
Mediocre

Juan,Dec 2025

EZE - PTY

The outbound flight from Boston was awful. The handicapped services were the worst i have ever seen. NEVER AGAIN. THIS WAS NOT WORTH ANYWHERE NEAR $4K.
American Airlines
7.2
Good
11,370 reviews
Copa Airlines
7.5
Good
1,557 reviews

Comfort

7.4

Overall

7.5

Crew

8.1

Boarding

7.8

Food

6.8

Entertainment

6.8

Reviews

1 / 20
2.0
Mediocre

Juan,Dec 2025

EZE - PTY

The outbound flight from Boston was awful. The handicapped services were the worst i have ever seen. NEVER AGAIN. THIS WAS NOT WORTH ANYWHERE NEAR $4K.

Related info for your journey

Find useful and relevant information for your journey from Denver to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Denver to Panama?

    If you book a flight to Panama from Denver, you will be flying from Denver Intl, which is the city’s only airport. Denver Intl (DEN) is located 18.5 mi from the center of Denver.

  • How popular is this Denver to Panama flight route?

    Within the past month, 31 users have taken a look at flights from Denver Intl to Panama.

  • How long is the flight from Denver to Panama?

    Departing from Denver to Panama will take you 5h 42m. The distance from Denver to Panama is about 2634 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest flights from Denver to Panama?

    Looking at all options, your cheapest flight can be booked for $155. While the most popular route (Denver Intl - Panama City Tocumen Intl) can be booked for $459 on average, our data indicates $621 when flying from Denver to Panama.

  • Can I find deals for flights from Denver to Panama that include hotel bookings?

    Yes. In addition to deals on Denver to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Panama.

  • Can I find deals for business class flights from Denver to Panama?

    Yes. Cheapflights offers flight deals from Denver to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to Panama?

    Currently, October is the cheapest month in which you can book a flight from Denver to Panama (average of $442). Flying from Denver to Panama in March is currently the most expensive (average of $526). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 3 airlines flying from Denver to Panama

Discover the top 3 airlines that operate flights from Denver to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 1, 2026.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$469Average$614FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$473Average$650FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$527Average$683FlexibilityNo cancel feeOn-time69%

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