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$153+ Cheap flights from Denver (DEN) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/22. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — PTY
dic. 20 — dic. 271
sáb. 12/20
sáb. 12/27
1 adult, Economy
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Find flight deals from Denver to Panama

Cheapest flights from Denver to Panama
Explore the most affordable flight options available from Denver to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on noviembre 20, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/111:14 pmDEN - PTY
1 stop9h 26mMultiple Airlines
vie. 12/510:25 amPTY - DEN
2 stops14h 34mMultiple Airlines
Deal found 11/18$573
This United Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/165:02 amDEN - PTY
1 stop10h 05mUnited Airlines
mar. 12/2311:35 amPTY - DEN
1 stop12h 31mUnited Airlines
Deal found 11/18$589
This Kiwi.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/2810:29 pmDEN - PTY
1 stop28h 51mMultiple Airlines
dom. 1/119:45 amPTY - DEN
2 stops32h 06mMultiple Airlines
Deal found 11/19$590
This American Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/164:51 pmDEN - PTY
2 stops18h 56mAmerican Airlines
mar. 12/234:55 pmPTY - DEN
2 stops20h 27mAmerican Airlines
Deal found 11/18$593
This Kiwi.com deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/810:29 pmDEN - PTY
1 stop28h 51mMultiple Airlines
lun. 12/1511:25 amPTY - DEN
2 stops37h 39mMultiple Airlines
Deal found 11/20$605
This United Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/165:02 amDEN - PTY
1 stop7h 43mUnited Airlines
mar. 2/38:55 amPTY - DEN
1 stop9h 26mUnited Airlines
Deal found 11/19$608
This American Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/164:51 pmDEN - PTY
2 stops18h 56mAmerican Airlines
mar. 2/32:27 pmPTY - DEN
1 stop9h 43mAmerican Airlines
Deal found 11/19$612
This Kiwi.com deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/1311:25 pmDEN - PTY
2 stops17h 30mMultiple Airlines
mié. 12/241:45 pmPTY - DEN
1 stop22h 18mMultiple Airlines
Deal found 11/20$616
This United Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/125:02 amDEN - PTY
1 stop10h 05mUnited Airlines
mar. 12/234:41 pmPTY - DEN
1 stop9h 03mUnited Airlines
Deal found 11/20$621
This American Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/912:47 pmDEN - PTY
1 stop23h 00mAmerican Airlines
jue. 1/154:50 pmPTY - DEN
2 stops23h 24mAmerican Airlines
Deal found 11/18$626
This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/2511:07 amDEN - PTY
2 stops35h 33mMultiple Airlines
mar. 12/23:39 pmPTY - DEN
1 stop19h 54mMultiple Airlines
Deal found 11/18$634

Cheap flight deals from Denver to Panama

Keep the following information in mind while searching for Denver to Panama flight deals. Data was last updated noviembre 20, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$548
(Copa Airlines)

One-way from

$153
(Kiwi.com)

Popular in

March

Cheapest in

August

Average price

$688

Good round-trip deal

$490 or less

Good one-way deal

$176 or less
Provider with most accurate pricing for Denver Intl-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Denver Intl-Panama City Tocumen Intl flights.
Search Deals
From Denver Intl to Panama
Search Deals
One-way flight from Denver Intl to Panama
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($29 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals
Price to beat on a round-trip flight from Denver Intl to Panama.
Search Deals
Price to beat on a one-way flight from Denver Intl to Panama.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Denver to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 20, 2025.
Use the filters below to find and compare flights from Denver to Panama that are best for you.

Fly from

Denver

Fly to

Panama

Route

Depart

Return

Price

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

sáb. 1/17

9:38 pm-5:33 am

Nonstop5h 55m

Panama City Tocumen Intl

mié. 1/28

12:56 pm-5:16 pm

Nonstop6h 20m

$548

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

mar. 1/13

9:38 pm-5:33 am

Nonstop5h 55m

Panama City Tocumen Intl

sáb. 1/17

12:56 pm-5:16 pm

Nonstop6h 20m

$548

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

mar. 1/13

9:38 pm-5:33 am

Nonstop5h 55m

Panama City Tocumen Intl

vie. 1/23

12:56 pm-5:16 pm

Nonstop6h 20m

$548

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

mar. 1/13

9:38 pm-5:33 am

Nonstop5h 55m

Panama City Tocumen Intl

jue. 1/22

12:56 pm-5:16 pm

Nonstop6h 20m

$548

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

jue. 2/5

10:19 pm-6:10 am

Nonstop5h 51m

Panama City Tocumen Intl

lun. 2/9

12:56 pm-5:16 pm

Nonstop6h 20m

$548

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

mié. 3/11

5:00 am-1:45 pm

1 stop7h 45m

Panama City Tocumen Intl

mié. 3/18

3:41 pm-11:44 pm

1 stop9h 03m

$550

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

vie. 2/27

7:45 am-7:38 pm

1 stop9h 53m

Panama City Tocumen Intl

dom. 3/8

3:41 pm-6:40 am

1 stop15h 59m

$550

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

dom. 3/1

7:45 am-5:07 pm

1 stop7h 22m

Panama City Tocumen Intl

lun. 3/9

3:41 pm-11:44 pm

1 stop9h 03m

$550

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

jue. 3/5

7:45 am-5:07 pm

1 stop7h 22m

Panama City Tocumen Intl

mar. 3/10

11:35 am-7:54 pm

1 stop9h 19m

$550

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

mar. 3/17

5:00 am-1:45 pm

1 stop7h 45m

Panama City Tocumen Intl

mar. 3/24

11:35 am-11:44 pm

1 stop13h 09m

$550

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/18

Showing 1-10 of 24 results
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Best time to book a flight from Denver to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to Panama

What is the cheapest month to book a flight from Denver to Panama?

Currently, March is the cheapest month in which you can book a flight from Denver to Panama (average of $354). Flying from Denver to Panama in June is currently the most expensive (average of $520). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to PA?

Find hourly flight availability from Denver to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated noviembre 20, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 53% on flights from Denver to Panama by exploring options for tickets at noon.

Weekly flight availability from Denver to Panama

Explore weekly flight availability from Denver to Panama. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated noviembre 20, 2025.

The most flights from DEN to PA0 are scheduled on a Monday (2 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated noviembre 20, 2025.
Get a feel of what it's like to fly with Delta, Copa Airlines, and United Airlines from Denver to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,002 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Boarding

8.1

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,002 reviews
Delta
7.9
Good
8,002 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Boarding

8.1

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Copa Airlines
7.6
Good
1,566 reviews
Delta
7.9
Good
8,002 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Boarding

8.1

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,028 reviews
Delta
7.9
Good
8,002 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Boarding

8.1

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,045 reviews
Delta
7.9
Good
8,002 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Boarding

8.1

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Denver to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Denver to Panama?

    If you book a flight to Panama from Denver, you will be flying from Denver Intl, which is the city’s only airport. Denver Intl (DEN) is located 18.5 mi from the center of Denver.

  • How popular is this Denver to Panama flight route?

    Within the past month, 38 users have taken a look at flights from Denver Intl to Panama.

  • How long is the flight from Denver to Panama?

    Departing from Denver to Panama will take you 5h 55m. The distance from Denver to Panama is about 2634 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest flights from Denver to Panama?

    Looking at all options, your cheapest flight can be booked for $138. While the most popular route (Denver Intl - Panama City Tocumen Intl) can be booked for $495 on average, our data indicates $863 when flying from Denver to Panama.

  • Can I find deals for flights from Denver to Panama that include hotel bookings?

    Yes. In addition to deals on Denver to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Panama.

  • Can I find deals for business class flights from Denver to Panama?

    Yes. Cheapflights offers flight deals from Denver to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to Panama?

    Currently, March is the cheapest month in which you can book a flight from Denver to Panama (average of $354). Flying from Denver to Panama in June is currently the most expensive (average of $520). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Denver to Panama

See prices for flight routes from nearby airports that may be better suited for you.
Denver to San José flights
Denver to Liberia flights
Denver to Philip S.W.Goldson flights
Denver to Panama City flights
Denver to Guatemala City flights
Denver to San Salvador flights
Denver to Managua flights
Denver to San Pedro Sula flights
Denver to Coxen Hole flights
Durango to San José flights
Colorado Springs to San José flights
Grand Junction to Liberia flights
Grand Junction to San José flights
Montrose to San José flights
Colorado Springs to Liberia flights
Colorado Springs to Guatemala City flights
Colorado Springs to Philip S.W.Goldson flights
Vail to San José flights
Vail to Liberia flights
Grand Junction to Guatemala City flights
Durango to Philip S.W.Goldson flights
Montrose to Liberia flights
Gunnison to Liberia flights
Aspen to San Salvador flights
Montrose to Managua flights
Colorado Springs to Panama City flights
Durango to Coxen Hole flights
Aspen to San José flights
Grand Junction to Managua flights
Durango to Managua flights
Montrose to San Salvador flights
Montrose to Philip S.W.Goldson flights
Gunnison to San Salvador flights
Vail to San Salvador flights
Denver to Tegucigalpa flights
Cortez to San José flights
Colorado Springs to Managua flights
Denver to San Pedro Town flights

Top 4 airlines flying from Denver to Panama

Discover the top 4 airlines that operate flights from Denver to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$492Average$651FlexibilityNo cancel feeOn-time70%
DeltaCheapest$527Average$924FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$527Average$667FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$527Average$692FlexibilityNo cancel feeOn-time69%

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