$267+ Cheap flights from Denver (DEN) to Panama
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/1. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — PTY
Jun 21 — Jun 281
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Denver to Panama with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Denver to Panama
Cheapest
Best
Last-minute
One-way
Cheapest flights from Denver to PanamaExplore the most affordable flight options available from Denver to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 22, 2026.
Explore the most affordable flight options available from Denver to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 22, 2026.
This Copa Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/2110:42 pm
DEN
- PTY
Nonstop5h 50m
Copa Airlines
Fri 6/2612:56 pm
PTY
- DEN
Nonstop6h 29m
Copa Airlines
Deal found 5/18![Copa Airlines logo]()
$500
This Delta deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/194:43 pm
DEN
- PTY
1 stop19h 16m
Delta
Mon 6/222:24 pm
PTY
- DEN
1 stop10h 58m
Delta
Deal found 5/18![Delta logo]()
$515
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/162:11 pm
DEN
- PTY
2 stops21h 02m
American Airlines
Tue 6/231:15 pm
PTY
- DEN
2 stops23h 10m
American Airlines
Deal found 5/19![American Airlines logo]()
$539
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/42:11 pm
DEN
- PTY
2 stops21h 02m
American Airlines
Thu 6/181:15 pm
PTY
- DEN
2 stops23h 14m
American Airlines
Deal found 5/19![American Airlines logo]()
$554
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1212:40 am
DEN
- PTY
1 stop11h 19m
Delta
Sun 6/282:24 pm
PTY
- DEN
1 stop19h 11m
Delta
Deal found 5/19![Delta logo]()
$555
This Copa Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/1510:42 pm
DEN
- PTY
Nonstop5h 50m
Copa Airlines
Sun 6/2112:56 pm
PTY
- DEN
Nonstop6h 29m
Copa Airlines
Deal found 5/19![Copa Airlines logo]()
$558
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/104:43 pm
DEN
- PTY
1 stop19h 26m
Delta
Tue 6/232:24 pm
PTY
- DEN
1 stop10h 58m
Delta
Deal found 5/19![Delta logo]()
$566
This Copa Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/410:42 pm
DEN
- PTY
Nonstop5h 50m
Copa Airlines
Thu 6/1112:56 pm
PTY
- DEN
Nonstop6h 29m
Copa Airlines
Deal found 5/18![Copa Airlines logo]()
$570
This Copa Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/2510:42 pm
DEN
- PTY
Nonstop5h 50m
Copa Airlines
Wed 7/812:56 pm
PTY
- DEN
Nonstop6h 24m
Copa Airlines
Deal found 5/18![Copa Airlines logo]()
$574
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/104:43 pm
DEN
- PTY
1 stop19h 26m
Delta
Fri 6/192:24 pm
PTY
- DEN
1 stop19h 54m
Delta
Deal found 5/19![Delta logo]()
$578
Best flights from Denver to PanamaDiscover carefully curated flight deals from Denver to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 22, 2026.
Discover carefully curated flight deals from Denver to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 22, 2026.
This Delta deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/14:41 pm
DEN
- PTY
1 stop19h 09m
Delta
Sat 6/62:15 pm
PTY
- DEN
1 stop19h 20m
Delta
Deal found 5/18![Delta logo]()
$585
This Copa Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/310:43 pm
DEN
- PTY
Nonstop5h 50m
Copa Airlines
Sat 9/1212:56 pm
PTY
- DEN
Nonstop6h 15m
Copa Airlines
Deal found 5/19![Copa Airlines logo]()
$632
This United Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/98:28 pm
DEN
- PTY
1 stop16h 46m
United Airlines
Thu 7/1610:00 am
PTY
- DEN
1 stop9h 23m
United Airlines
Deal found 5/20![United Airlines logo]()
$642
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/512:56 am
DEN
- PTY
1 stop10h 54m
Delta
Fri 6/122:24 pm
PTY
- DEN
1 stop10h 58m
Delta
Deal found 5/19![Delta logo]()
$585
This Copa Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/2610:42 pm
DEN
- PTY
Nonstop5h 50m
Copa Airlines
Mon 8/312:56 pm
PTY
- DEN
Nonstop6h 24m
Copa Airlines
Deal found 5/22![Copa Airlines logo]()
$647
This United Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:00 am
DEN
- PTY
1 stop12h 38m
United Airlines
Tue 11/38:55 am
PTY
- DEN
1 stop16h 32m
United Airlines
Deal found 5/22![United Airlines logo]()
$652
This Copa Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/210:42 pm
DEN
- PTY
Nonstop5h 50m
Copa Airlines
Thu 7/912:56 pm
PTY
- DEN
Nonstop6h 24m
Copa Airlines
Deal found 5/21![Copa Airlines logo]()
$648
This United Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/29:10 pm
DEN
- PTY
1 stop18h 02m
United Airlines
Thu 7/93:30 pm
PTY
- DEN
1 stop9h 27m
United Airlines
Deal found 5/20![United Airlines logo]()
$653
This Copa Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/910:42 pm
DEN
- PTY
Nonstop5h 50m
Copa Airlines
Thu 7/1612:56 pm
PTY
- DEN
Nonstop6h 24m
Copa Airlines
Deal found 5/21![Copa Airlines logo]()
$648
This United Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:27 pm
DEN
- PTY
1 stop16h 47m
United Airlines
Fri 10/163:30 pm
PTY
- DEN
1 stop17h 22m
United Airlines
Deal found 5/18![United Airlines logo]()
$663
This United Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/69:10 pm
DEN
- PTY
1 stop16h 04m
United Airlines
Thu 7/1610:00 am
PTY
- DEN
1 stop13h 15m
United Airlines
Deal found 5/18![United Airlines logo]()
$668
Last-minute flights from Denver to PanamaDiscover last-minute flight deals from Denver to Panama. Data last updated May 22, 2026 and is based on user searches.
Discover last-minute flight deals from Denver to Panama. Data last updated May 22, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/42:11 pm
DEN
- PTY
2 stops21h 02m
American Airlines
Thu 6/181:15 pm
PTY
- DEN
2 stops23h 14m
American Airlines
Deal found 5/19![American Airlines logo]()
$554
This Copa Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/410:42 pm
DEN
- PTY
Nonstop5h 50m
Copa Airlines
Thu 6/1112:56 pm
PTY
- DEN
Nonstop6h 29m
Copa Airlines
Deal found 5/18![Copa Airlines logo]()
$570
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/104:43 pm
DEN
- PTY
1 stop19h 26m
Delta
Fri 6/262:24 pm
PTY
- DEN
1 stop10h 58m
Delta
Deal found 5/19![Delta logo]()
$566
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/104:43 pm
DEN
- PTY
1 stop19h 26m
Delta
Fri 6/192:24 pm
PTY
- DEN
1 stop19h 54m
Delta
Deal found 5/19![Delta logo]()
$578
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1212:40 am
DEN
- PTY
1 stop11h 19m
Delta
Tue 6/232:24 pm
PTY
- DEN
1 stop10h 58m
Delta
Deal found 5/19![Delta logo]()
$555
This Copa Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/1510:42 pm
DEN
- PTY
Nonstop5h 50m
Copa Airlines
Sun 6/2112:56 pm
PTY
- DEN
Nonstop6h 29m
Copa Airlines
Deal found 5/19![Copa Airlines logo]()
$558
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/162:11 pm
DEN
- PTY
2 stops21h 02m
American Airlines
Tue 6/231:15 pm
PTY
- DEN
2 stops23h 10m
American Airlines
Deal found 5/19![American Airlines logo]()
$539
This Delta deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/194:43 pm
DEN
- PTY
1 stop19h 16m
Delta
Mon 6/222:24 pm
PTY
- DEN
1 stop10h 58m
Delta
Deal found 5/18![Delta logo]()
$515
This Copa Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/2110:42 pm
DEN
- PTY
Nonstop5h 50m
Copa Airlines
Fri 6/2612:56 pm
PTY
- DEN
Nonstop6h 29m
Copa Airlines
Deal found 5/18![Copa Airlines logo]()
$500
This Copa Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/2510:42 pm
DEN
- PTY
Nonstop5h 50m
Copa Airlines
Wed 7/812:56 pm
PTY
- DEN
Nonstop6h 24m
Copa Airlines
Deal found 5/18![Copa Airlines logo]()
$574
One-way flights from Denver to PanamaSearch for one-way flight options from Denver to Panama. Find affordable one-way fares based on user searches. Data last updated May 22, 2026.
Search for one-way flight options from Denver to Panama. Find affordable one-way fares based on user searches. Data last updated May 22, 2026.
This Expedia deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/13:15 pm
DEN
- PTY
2 stops18h 15m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$267
This Travelocity deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/31:03 pm
DEN
- PTY
3 stops24h 52m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$274
This Travelocity deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3011:41 pm
DEN
- PTY
2 stops33h 49m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/58:40 am
DEN
- PTY
2 stops33h 40m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$288
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/151:53 pm
DEN
- PTY
2 stops33h 42m
Multiple Airlines
Deal found 5/19![Multiple Airlines logo]()
$305
This Orbitz deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/11:03 pm
DEN
- PTY
2 stops20h 27m
Multiple Airlines
Deal found 5/19![Multiple Airlines logo]()
$307
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/131:53 pm
DEN
- PTY
3 stops33h 42m
Multiple Airlines
Deal found 5/19![Multiple Airlines logo]()
$312
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/39:06 pm
DEN
- PTY
3 stops34h 00m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$313
This Kiwi.com deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/201:53 pm
DEN
- PTY
3 stops33h 42m
Multiple Airlines
Deal found 5/22![Multiple Airlines logo]()
$314
This Kiwi.com deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/191:53 pm
DEN
- PTY
3 stops33h 42m
Multiple Airlines
Deal found 5/22![Multiple Airlines logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/37:00 am
DEN
- PAC
3 stops34h 30m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$751
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/157:40 am
DEN
- PAC
3 stops33h 50m
Multiple Airlines
Deal found 5/19![Multiple Airlines logo]()
$780
Find flight deals from Denver to Panama
Keep the following information in mind while searching for Denver to Panama flight deals. Data was last updated May 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $500 (Copa Airlines) |
One-way from | $267 (Expedia) |
Popular in | December |
Cheapest in | August |
Average price | $602 |
Good round-trip deal | $553 or less |
Good one-way deal | $258 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Denver to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 22, 2026.
Use the filters below to find and compare flights from Denver to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Mon 6/1
4:41 pm-12:50 pm
1 stop19h 09m
Panama City Tocumen Intl
Sat 6/6
2:15 pm-8:35 am
1 stop19h 20m
$585
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Fri 6/5
12:56 am-12:50 pm
1 stop10h 54m
Panama City Tocumen Intl
Fri 6/12
2:24 pm-12:22 am
1 stop10h 58m
$585
Quickest round-trip
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Thu 9/3
10:43 pm-5:33 am
Nonstop5h 50m
Panama City Tocumen Intl
Sat 9/12
12:56 pm-6:11 pm
Nonstop6h 15m
$632
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Thu 7/9
8:28 pm-2:14 pm
1 stop16h 46m
Panama City Tocumen Intl
Thu 7/16
10:00 am-6:23 pm
1 stop9h 23m
$642
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Sun 7/26
10:42 pm-5:32 am
Nonstop5h 50m
Panama City Tocumen Intl
Mon 8/3
12:56 pm-6:20 pm
Nonstop6h 24m
$647
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Thu 7/2
10:42 pm-5:32 am
Nonstop5h 50m
Panama City Tocumen Intl
Thu 7/9
12:56 pm-6:20 pm
Nonstop6h 24m
$648
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Thu 7/9
10:42 pm-5:32 am
Nonstop5h 50m
Panama City Tocumen Intl
Thu 7/16
12:56 pm-6:20 pm
Nonstop6h 24m
$648
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Sun 11/1
5:00 am-7:38 pm
1 stop12h 38m
Panama City Tocumen Intl
Tue 11/3
8:55 am-11:27 pm
1 stop16h 32m
$652
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Thu 7/2
9:10 pm-4:12 pm
1 stop18h 02m
Panama City Tocumen Intl
Thu 7/9
3:30 pm-11:57 pm
1 stop9h 27m
$653
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Fri 10/9
8:27 pm-2:14 pm
1 stop16h 47m
Panama City Tocumen Intl
Fri 10/16
3:30 pm-7:52 am
1 stop17h 22m
$663
Showing 1-10 of 25 resultsSorted by cheapest first
Best time to book a flight from Denver to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from Denver with our price prediction graph.
DEN-PTY
DEN-PAC
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Denver to Panama
DEN-PA0
DEN-PTY
DEN-PAC
What is the cheapest month to book a flight from Denver to Panama?
Currently, March is the cheapest month in which you can book a flight from Denver to Panama (average of $234). Flying from Denver to Panama in July is currently the most expensive (average of $518). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DEN to PA?
Find hourly flight availability from Denver to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 22, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Denver to Panama as you normally would.
How far ahead should I book a flight from Denver to Panama?
To ensure you get the cheapest price possible for a flight from Denver to Panama, you should look to book at least 68 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated May 22, 2026.
Get a feel of what it's like to fly with Copa Airlines and United Airlines from Denver to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.9
Boarding
7.8
Crew
8.1
Overall
7.5
Comfort
7.4
Entertainment
6.8
Reviews
1 / 20
10.0
ExcellentAnonymous,Apr 2026
LIM - PTY
Food
6.9
Boarding
7.8
Crew
8.1
Overall
7.5
Comfort
7.4
Entertainment
6.8
Reviews
1 / 20
10.0
ExcellentAnonymous,Apr 2026
LIM - PTY
Food
6.9
Boarding
7.8
Crew
8.1
Overall
7.5
Comfort
7.4
Entertainment
6.8
Reviews
1 / 20
10.0
ExcellentAnonymous,Apr 2026
LIM - PTY
Related info for your journey
Find useful and relevant information for your journey from Denver to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Alternative routes for Denver to Panama
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Denver to Panama by cabin class
Find flights from Denver to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Denver and Panama flights
Browse other Denver and Panama flight options. Last updated on May 22, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Denver to Panama
Discover the top 2 airlines that operate flights from Denver to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$474 | Average$643 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$527 | Average$680 | FlexibilityNo cancel fee | On-time69% |