$267+ Cheap flights from Denver (DEN) to Panama
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/21. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — PTY
Aug 21 — Aug 281
Round-trip
1 adult, Economy
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Last-minute
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Cheapest flights from Denver to PanamaExplore the most affordable flight options available from Denver to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 22, 2026.
Explore the most affordable flight options available from Denver to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 22, 2026.
This Copa Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1010:43 pm
DEN
- PTY
Nonstop5h 50m
Copa Airlines
Mon 9/1412:56 pm
PTY
- DEN
Nonstop6h 15m
Copa Airlines
Deal found 7/22![Copa Airlines logo]()
$520
This Orbitz deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/233:15 pm
DEN
- PTY
3 stops22h 40m
Multiple Airlines
Tue 10/273:50 pm
PTY
- DEN
2 stops23h 44m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$586
This Expedia deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/233:15 pm
DEN
- PTY
3 stops22h 40m
Multiple Airlines
Fri 10/3011:25 am
PTY
- DEN
3 stops28h 09m
Multiple Airlines
Deal found 7/18![Multiple Airlines logo]()
$593
This Orbitz deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/811:59 pm
DEN
- PTY
3 stops37h 56m
Multiple Airlines
Thu 9/243:50 pm
PTY
- DEN
2 stops23h 28m
Multiple Airlines
Deal found 7/18![Multiple Airlines logo]()
$597
This Copa Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1510:43 pm
DEN
- PTY
Nonstop5h 50m
Copa Airlines
Sat 9/512:56 pm
PTY
- DEN
Nonstop6h 15m
Copa Airlines
Deal found 7/21![Copa Airlines logo]()
$606
This Copa Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:49 pm
DEN
- PTY
Nonstop5h 44m
Copa Airlines
Wed 4/1412:45 pm
PTY
- DEN
Nonstop6h 19m
Copa Airlines
Deal found 7/22![Copa Airlines logo]()
$612
This Expedia deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/292:05 pm
DEN
- PTY
3 stops23h 50m
Multiple Airlines
Wed 8/511:25 am
PTY
- DEN
3 stops26h 46m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$671
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/251:53 pm
DEN
- PTY
1 stop23h 12m
Multiple Airlines
Mon 8/313:10 pm
PTY
- DEN
2 stops18h 13m
Multiple Airlines
Deal found 7/20![Multiple Airlines logo]()
$678
This Trip.com deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/510:49 pm
DEN
- PTY
2 stops14h 26m
Multiple Airlines
Thu 9/104:25 am
PTY
- DEN
2 stops30h 23m
Multiple Airlines
Deal found 7/18![Multiple Airlines logo]()
$683
This Copa Airlines deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/1310:43 pm
DEN
- PTY
Nonstop5h 50m
Copa Airlines
Thu 9/1712:56 pm
PTY
- DEN
Nonstop6h 15m
Copa Airlines
Deal found 7/17![Copa Airlines logo]()
$687
Best flights from Denver to PanamaDiscover carefully curated flight deals from Denver to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 22, 2026.
Discover carefully curated flight deals from Denver to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 22, 2026.
This Copa Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1510:43 pm
DEN
- PTY
Nonstop5h 50m
Copa Airlines
Sat 9/512:56 pm
PTY
- DEN
Nonstop6h 15m
Copa Airlines
Deal found 7/21![Copa Airlines logo]()
$606
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/45:00 am
DEN
- PTY
1 stop7h 45m
United Airlines
Tue 11/108:55 am
PTY
- DEN
1 stop11h 16m
United Airlines
Deal found 7/21![United Airlines logo]()
$692
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:00 am
DEN
- PTY
1 stop7h 45m
United Airlines
Fri 11/274:41 pm
PTY
- DEN
1 stop8h 42m
United Airlines
Deal found 7/21![United Airlines logo]()
$692
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/228:30 pm
DEN
- PTY
1 stop16h 15m
United Airlines
Fri 11/274:41 pm
PTY
- DEN
1 stop8h 42m
United Airlines
Deal found 7/21![United Airlines logo]()
$692
This United Airlines deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/138:31 pm
DEN
- PTY
1 stop16h 43m
United Airlines
Thu 9/173:30 pm
PTY
- DEN
1 stop16h 17m
United Airlines
Deal found 7/17![United Airlines logo]()
$702
This United Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/810:07 am
DEN
- PTY
1 stop7h 30m
United Airlines
Thu 9/2410:00 am
PTY
- DEN
1 stop11h 08m
United Airlines
Deal found 7/19![United Airlines logo]()
$702
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:33 pm
DEN
- PTY
1 stop17h 41m
United Airlines
Mon 10/510:00 am
PTY
- DEN
1 stop11h 08m
United Airlines
Deal found 7/20![United Airlines logo]()
$702
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/65:00 am
DEN
- PTY
1 stop8h 14m
United Airlines
Mon 9/143:30 pm
PTY
- DEN
1 stop16h 17m
United Airlines
Deal found 7/20![United Airlines logo]()
$713
Last-minute flights from Denver to PanamaDiscover last-minute flight deals from Denver to Panama. Data last updated July 22, 2026 and is based on user searches.
Discover last-minute flight deals from Denver to Panama. Data last updated July 22, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/292:05 pm
DEN
- PTY
3 stops23h 50m
Multiple Airlines
Wed 8/511:25 am
PTY
- DEN
3 stops26h 46m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$671
This Expedia deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/511:59 pm
DEN
- PTY
2 stops33h 31m
Multiple Airlines
Wed 8/195:30 am
PTY
- DEN
2 stops12h 15m
Multiple Airlines
Deal found 7/20![Multiple Airlines logo]()
$715
This Expedia deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/82:04 pm
DEN
- PTY
2 stops19h 26m
Multiple Airlines
Sat 8/155:30 am
PTY
- DEN
2 stops13h 55m
Multiple Airlines
Deal found 7/19![Multiple Airlines logo]()
$704
This Trip.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1211:40 pm
DEN
- PTY
2 stops13h 35m
Multiple Airlines
Fri 9/253:10 pm
PTY
- DEN
2 stops19h 38m
Multiple Airlines
Deal found 7/20![Multiple Airlines logo]()
$710
This Copa Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1510:43 pm
DEN
- PTY
Nonstop5h 50m
Copa Airlines
Sat 9/512:56 pm
PTY
- DEN
Nonstop6h 15m
Copa Airlines
Deal found 7/21![Copa Airlines logo]()
$606
This United Airlines deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/157:30 pm
DEN
- PTY
1 stop17h 44m
United Airlines
Sat 9/510:00 am
PTY
- DEN
1 stop11h 09m
United Airlines
Deal found 7/17![United Airlines logo]()
$713
This American Airlines deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/154:21 pm
DEN
- PTY
2 stops19h 18m
American Airlines
Sat 9/51:39 pm
PTY
- DEN
2 stops21h 07m
American Airlines
Deal found 7/17![American Airlines logo]()
$717
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/181:53 pm
DEN
- PTY
1 stop23h 12m
Multiple Airlines
Sun 8/233:10 pm
PTY
- DEN
2 stops18h 13m
Multiple Airlines
Deal found 7/20![Multiple Airlines logo]()
$703
This Copa Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1910:43 pm
DEN
- PTY
Nonstop5h 50m
Copa Airlines
Wed 8/2612:56 pm
PTY
- DEN
Nonstop6h 24m
Copa Airlines
Deal found 7/21![Copa Airlines logo]()
$708
This Kiwi.com deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2210:49 pm
DEN
- PTY
1 stop8h 41m
Multiple Airlines
Sat 8/299:33 pm
PTY
- DEN
2 stops17h 28m
Multiple Airlines
Deal found 7/17![Multiple Airlines logo]()
$688
This Trip.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2410:49 pm
DEN
- PTY
2 stops24h 46m
Multiple Airlines
Thu 9/105:30 am
PTY
- DEN
3 stops29h 18m
Multiple Airlines
Deal found 7/19![Multiple Airlines logo]()
$712
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/251:53 pm
DEN
- PTY
1 stop23h 12m
Multiple Airlines
Mon 8/313:10 pm
PTY
- DEN
2 stops18h 13m
Multiple Airlines
Deal found 7/20![Multiple Airlines logo]()
$678
One-way flights from Denver to PanamaSearch for one-way flight options from Denver to Panama. Find affordable one-way fares based on user searches. Data last updated July 22, 2026.
Search for one-way flight options from Denver to Panama. Find affordable one-way fares based on user searches. Data last updated July 22, 2026.
This Expedia deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/213:15 pm
DEN
- PTY
2 stops18h 15m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$267
This Travelocity deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/811:59 pm
DEN
- PTY
2 stops33h 31m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$284
This Expedia deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/311:59 pm
DEN
- PTY
2 stops48h 56m
Multiple Airlines
Deal found 7/18![Multiple Airlines logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1111:59 pm
DEN
- PTY
2 stops31h 31m
Multiple Airlines
Deal found 7/17![Multiple Airlines logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/28:40 am
DEN
- PTY
2 stops22h 04m
Multiple Airlines
Deal found 7/20![Multiple Airlines logo]()
$332
This Mytrip deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/121:53 pm
DEN
- PTY
2 stops26h 07m
Multiple Airlines
Deal found 7/17![Multiple Airlines logo]()
$358
This Avianca deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1710:05 am
DEN
- PTY
2 stops14h 50m
Avianca
Deal found 7/19![Avianca logo]()
$371
This Avianca deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/229:09 pm
DEN
- PTY
2 stops12h 21m
Avianca
Deal found 7/19![Avianca logo]()
$387
This Kiwi.com deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1211:59 pm
DEN
- PAC
3 stops59h 16m
Multiple Airlines
Deal found 7/17![Multiple Airlines logo]()
$666
This Kiwi.com deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/37:40 am
DEN
- PAC
3 stops33h 50m
Multiple Airlines
Deal found 7/18![Multiple Airlines logo]()
$711
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/83:20 pm
DEN
- PAC
3 stops40h 55m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$755
This Kiwi.com deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/1812:24 pm
DEN
- PAC
3 stops28h 06m
Multiple Airlines
Deal found 7/17![Multiple Airlines logo]()
$767
Find flight deals from Denver to Panama
Keep the following information in mind while searching for Denver to Panama flight deals. Data was last updated July 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $593 (Expedia) |
One-way from | $267 (Expedia) |
Popular in | December |
Cheapest in | April |
Average price | $667 |
Good round-trip deal | $592 or less |
Good one-way deal | $255 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Denver to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 22, 2026.
Use the filters below to find and compare flights from Denver to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Sat 8/15
10:43 pm-5:33 am
Nonstop5h 50m
Panama City Tocumen Intl
Sat 9/5
12:56 pm-6:11 pm
Nonstop6h 15m
$606
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Wed 11/4
5:00 am-2:45 pm
1 stop7h 45m
Panama City Tocumen Intl
Tue 11/10
8:55 am-6:11 pm
1 stop11h 16m
$692
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Thu 11/19
5:00 am-2:45 pm
1 stop7h 45m
Panama City Tocumen Intl
Fri 11/27
4:41 pm-11:23 pm
1 stop8h 42m
$692
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Sun 11/22
8:30 pm-2:45 pm
1 stop16h 15m
Panama City Tocumen Intl
Fri 11/27
4:41 pm-11:23 pm
1 stop8h 42m
$692
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Sun 9/13
8:31 pm-2:14 pm
1 stop16h 43m
Panama City Tocumen Intl
Thu 9/17
3:30 pm-6:47 am
1 stop16h 17m
$702
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Tue 9/8
10:07 am-6:37 pm
1 stop7h 30m
Panama City Tocumen Intl
Thu 9/24
10:00 am-8:08 pm
1 stop11h 08m
$702
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Fri 10/2
7:33 pm-2:14 pm
1 stop17h 41m
Panama City Tocumen Intl
Mon 10/5
10:00 am-8:08 pm
1 stop11h 08m
$702
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Sun 9/6
5:00 am-2:14 pm
1 stop8h 14m
Panama City Tocumen Intl
Mon 9/14
3:30 pm-6:47 am
1 stop16h 17m
$713
Cheapest one-way
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Sat 8/8
11:59 pm-10:30 am
2 stops33h 31m
$284
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Mon 11/2
7:38 pm-4:01 pm
3 stops42h 23m
$351
Showing 1-10 of 18 resultsSorted by cheapest first
Best time to book a flight from Denver to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from Denver with our price prediction graph.
DEN-PTY
DEN-PAC
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Denver to Panama
DEN-PA0
DEN-PTY
DEN-PAC
What is the cheapest month to book a flight from Denver to Panama?
Currently, April is the cheapest month in which you can book a flight from Denver to Panama (average of $597). Flying from Denver to Panama in December is currently the most expensive (average of $765). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DEN to PA?
Find hourly flight availability from Denver to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 22, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Denver to Panama as you normally would.
Weekly flight availability from Denver to Panama
Explore weekly flight availability from Denver to Panama. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated July 22, 2026.
The most flights from DEN to PA0 are scheduled on a Monday (2 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).
How far ahead should I book a flight from Denver to Panama?
To ensure you get the cheapest price possible for a flight from Denver to Panama, you should look to book at least 67 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated July 22, 2026.
Get a feel of what it's like to fly with Copa Airlines,United Airlines, andAmerican Airlines from Denver to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.8
Boarding
7.8
Food
6.9
Overall
7.6
Comfort
7.4
Crew
8.1
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Entertainment
6.8
Boarding
7.8
Food
6.9
Overall
7.6
Comfort
7.4
Crew
8.1
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Entertainment
6.8
Boarding
7.8
Food
6.9
Overall
7.6
Comfort
7.4
Crew
8.1
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Entertainment
6.8
Boarding
7.8
Food
6.9
Overall
7.6
Comfort
7.4
Crew
8.1
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Related info for your journey
Find useful and relevant information for your journey from Denver to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Denver to Panama
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Denver and Panama flights
Browse other Denver and Panama flight options. Last updated on July 22, 2026.
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Top 3 airlines flying from Denver to Panama
Discover the top 3 airlines that operate flights from Denver to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$464 | Average$634 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$531 | Average$695 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$634 | Average$743 | FlexibilityNo cancel fee | On-time71% |