How popular is this Denver to Panama flight route?

Within the past month, 38 users have taken a look at flights from Denver Intl to Panama.

How long is the flight from Denver to Panama?

Departing from Denver to Panama will take you 5h 45m. The distance from Denver to Panama is about 2634 mi. Most flights are nonstop.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

What are the cheapest flights from Denver to Panama?

Looking at all options, your cheapest flight can be booked for $156. While the most popular route (Denver Intl - Panama City Tocumen Intl) can be booked for $535 on average, our data indicates $730 when flying from Denver to Panama.

What are the most popular airlines that fly from Denver to Panama?

Before booking your flight from Denver to Panama check out the most popular airlines for this route: Copa Airlines, United Airlines or American Airlines.

What airport do you fly from for flights from Denver to Panama?

If you book a flight to Panama from Denver, you will be flying from Denver Intl, which is the city’s only airport. Denver Intl (DEN) is located 18.5 mi from the center of Denver.

Can I find deals for flights from Denver to Panama that include hotel bookings?

Yes. In addition to deals on Denver to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Denver to Panama?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Panama.

Can I find deals for business class flights from Denver to Panama?

Yes. Cheapflights offers flight deals from Denver to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$179+ Flights from Denver to Panama

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Cheap flight deals from Denver to Panama

Cheapest flights from Denver to Panama
Explore the most affordable flight options available from Denver to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 2, 2026.

Wed 12/316:00 amDEN - PTY

3 stops50h 30mMultiple Airlines

Wed 1/73:50 pmPTY - DEN

2 stops20h 52mMultiple Airlines

Deal found 12/30

$644

Wed 12/313:48 pmDEN - PTY

1 stop16h 44mCopa Airlines

Wed 1/74:41 pmPTY - DEN

1 stop9h 00mCopa Airlines

Deal found 12/30

$785

Wed 12/3111:38 pmDEN - PTY

1 stop12h 15mAmerican Airlines

Wed 1/72:27 pmPTY - DEN

2 stops22h 04mAmerican Airlines

Deal found 12/30

$999

Best flights from Denver to Panama
Discover carefully curated flight deals from Denver to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated January 2, 2026.

Tue 2/105:59 pmDEN - PTY

3 stops18h 56mMultiple Airlines

Mon 2/163:50 pmPTY - DEN

2 stops19h 56mMultiple Airlines

Deal found 1/1

$532

Tue 3/2410:48 pmDEN - PTY

Nonstop5h 45mCopa Airlines

Tue 3/3112:56 pmPTY - DEN

Nonstop6h 20mCopa Airlines

Deal found 12/30

$548

Wed 5/277:50 amDEN - PTY

1 stop7h 22mUnited Airlines

Mon 6/17:55 amPTY - DEN

1 stop16h 32mUnited Airlines

Deal found 12/31

$550

Sat 2/289:38 pmDEN - PTY

Nonstop5h 55mCopa Airlines

Thu 4/3012:56 pmPTY - DEN

Nonstop6h 29mCopa Airlines

Deal found 12/31

$548

Tue 5/55:00 amDEN - PTY

1 stop12h 37mUnited Airlines

Fri 5/87:55 amPTY - DEN

1 stop14h 52mUnited Airlines

Deal found 12/31

$550

Sat 3/1410:48 pmDEN - PTY

Nonstop5h 45mCopa Airlines

Thu 3/1912:56 pmPTY - DEN

Nonstop6h 20mCopa Airlines

Deal found 12/31

$548

Thu 4/97:45 amDEN - PTY

1 stop7h 27mUnited Airlines

Mon 4/1310:00 amPTY - DEN

1 stop9h 21mUnited Airlines

Deal found 12/30

$550

Sat 3/1410:48 pmDEN - PTY

Nonstop5h 45mCopa Airlines

Tue 3/1712:56 pmPTY - DEN

Nonstop6h 20mCopa Airlines

Deal found 1/1

$549

Tue 5/268:39 pmDEN - PTY

1 stop16h 35mUnited Airlines

Mon 6/13:20 pmPTY - DEN

1 stop9h 07mUnited Airlines

Deal found 12/31

$550

Fri 2/2010:19 pmDEN - PTY

Nonstop5h 51mCopa Airlines

Tue 2/2412:56 pmPTY - DEN

Nonstop6h 20mCopa Airlines

Deal found 1/1

$549

Last-minute flights from Denver to Panama
Discover last-minute flight deals from Denver to Panama. Data last updated January 2, 2026 and is based on user searches.

Tue 1/2011:35 amDEN - PTY

3 stops29h 20mMultiple Airlines

Thu 1/293:50 pmPTY - DEN

2 stops20h 52mMultiple Airlines

Deal found 12/31

$535

Thu 1/2911:35 amDEN - PTY

3 stops29h 20mMultiple Airlines

Thu 2/53:50 pmPTY - DEN

2 stops20h 52mMultiple Airlines

Deal found 12/30

$497

Thu 1/2911:35 amDEN - PTY

3 stops29h 20mMultiple Airlines

Thu 2/263:50 pmPTY - DEN

2 stops21h 20mMultiple Airlines

Deal found 1/1

$516

Thu 1/2911:35 amDEN - PTY

3 stops29h 20mMultiple Airlines

Mon 2/211:25 amPTY - DEN

3 stops32h 59mMultiple Airlines

Deal found 1/1

$544

Fri 1/301:50 pmDEN - PTY

1 stop28h 44mMultiple Airlines

Fri 2/62:55 amPTY - DEN

2 stops20h 09mMultiple Airlines

Deal found 12/30

$533

Sat 1/316:00 amDEN - PTY

1 stop12h 34mMultiple Airlines

Sat 2/73:50 pmPTY - DEN

2 stops20h 09mMultiple Airlines

Deal found 1/1

$541

One-way flights from Denver to Panama
Search for one-way flight options from Denver to Panama. Find affordable one-way fares based on user searches. Data last updated January 2, 2026.

Tue 1/2711:20 amDEN - PTY

2 stops24h 40mMultiple Airlines

Deal found 12/30

$179

Mon 1/2610:46 amDEN - PTY

3 stops44h 04mMultiple Airlines

Deal found 1/1

$182

Tue 1/1311:59 pmDEN - PTY

3 stops32h 31mMultiple Airlines

Deal found 12/30

$192

Tue 1/207:30 amDEN - PTY

3 stops47h 20mMultiple Airlines

Deal found 12/30

$207

Wed 1/217:30 amDEN - PTY

3 stops47h 20mMultiple Airlines

Deal found 1/1

$209

Thu 1/229:05 pmDEN - PTY

3 stops33h 45mMultiple Airlines

Deal found 12/31

$221

Thu 1/2910:46 amDEN - PTY

2 stops20h 04mMultiple Airlines

Deal found 12/30

$229

Sun 1/256:16 pmDEN - PAC

3 stops46h 14mMultiple Airlines

Deal found 1/1

$548

Mon 2/166:00 amDEN - PAC

3 stops55h 15mMultiple Airlines

Deal found 1/1

$636

Find flight deals from Denver to Panama

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$497 (Expedia)
One-way from	$179 (Kiwi.com)
Popular in	December
Cheapest in	August
Average price	$647
Good round-trip deal	$463 or less
Good one-way deal	$279 or less

Provider with most accurate pricing for Denver Intl-Panama City Tocumen Intl flight deals.

Search Deals

Provider most trusted by Cheapflights users for Denver Intl-Panama City Tocumen Intl flights.

Search Deals

From Denver Intl to Panama

Search Deals

One-way flight from Denver Intl to Panama

Search Deals

Highest demand for flights based on searches. 6% potential increase in price ($47 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease ($10 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in January 2026

Search Deals

Price to beat on a round-trip flight from Denver Intl to Panama.

Search Deals

Price to beat on a one-way flight from Denver Intl to Panama.

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 2/10

5:59 pm-2:55 pm

3 stops18h 56m

Panama City Tocumen Intl

Mon 2/16

3:50 pm-9:46 am

2 stops19h 56m

$532

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 3/24

10:48 pm-5:33 am

Nonstop5h 45m

Panama City Tocumen Intl

Tue 3/31

12:56 pm-6:16 pm

Nonstop6h 20m

$548

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 2/28

9:38 pm-5:33 am

Nonstop5h 55m

Panama City Tocumen Intl

Thu 4/30

12:56 pm-6:25 pm

Nonstop6h 29m

$548

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 3/14

10:48 pm-5:33 am

Nonstop5h 45m

Panama City Tocumen Intl

Thu 3/19

12:56 pm-6:16 pm

Nonstop6h 20m

$548

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 3/14

10:48 pm-5:33 am

Nonstop5h 45m

Panama City Tocumen Intl

Tue 3/17

12:56 pm-6:16 pm

Nonstop6h 20m

$549

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 2/20

10:19 pm-6:10 am

Nonstop5h 51m

Panama City Tocumen Intl

Tue 2/24

12:56 pm-5:16 pm

Nonstop6h 20m

$549

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 5/27

7:50 am-4:12 pm

1 stop7h 22m

Panama City Tocumen Intl

Mon 6/1

7:55 am-11:27 pm

1 stop16h 32m

$550

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 5/5

5:00 am-6:37 pm

1 stop12h 37m

Panama City Tocumen Intl

Fri 5/8

7:55 am-9:47 pm

1 stop14h 52m

$550

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 4/9

7:45 am-4:12 pm

1 stop7h 27m

Panama City Tocumen Intl

Mon 4/13

10:00 am-6:21 pm

1 stop9h 21m

$550

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 5/26

8:39 pm-2:14 pm

1 stop16h 35m

Panama City Tocumen Intl

Mon 6/1

3:20 pm-11:27 pm

1 stop9h 07m

$550

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/1

Showing 1-10 of 20 results

Best time to book a flight from Denver to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Denver with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to Panama

What is the cheapest month to book a flight from Denver to Panama?

Currently, March is the cheapest month in which you can book a flight from Denver to Panama (average of $354). Flying from Denver to Panama in June is currently the most expensive (average of $520). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to PA?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Denver to Panama as you normally would.

Reviews of airlines servicing Panama

Get a feel of what it's like to fly with Delta, Copa Airlines, and United Airlines from Denver to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.9

Good

8,021 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Delta

7.9

Good

8,021 reviews

Delta

7.9

Good

8,021 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

Copa Airlines

7.6

Good

1,566 reviews

Delta

7.9

Good

8,021 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

United Airlines

7.4

Good

9,132 reviews

Delta

7.9

Good

8,021 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

American Airlines

7.2

Good

11,074 reviews

Delta

7.9

Good

8,021 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

Related info for your journey

What airport do you fly from for flights from Denver to Panama?
If you book a flight to Panama from Denver, you will be flying from Denver Intl, which is the city’s only airport. Denver Intl (DEN) is located 18.5 mi from the center of Denver.
How popular is this Denver to Panama flight route?
Within the past month, 38 users have taken a look at flights from Denver Intl to Panama.
How long is the flight from Denver to Panama?
Departing from Denver to Panama will take you 5h 45m. The distance from Denver to Panama is about 2634 mi. Most flights are nonstop.
What are the cheapest flights from Denver to Panama?
Looking at all options, your cheapest flight can be booked for $156. While the most popular route (Denver Intl - Panama City Tocumen Intl) can be booked for $535 on average, our data indicates $730 when flying from Denver to Panama.
Can I find deals for flights from Denver to Panama that include hotel bookings?
Yes. In addition to deals on Denver to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Denver to Panama?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Panama.
Can I find deals for business class flights from Denver to Panama?
Yes. Cheapflights offers flight deals from Denver to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Denver to Panama?
Currently, March is the cheapest month in which you can book a flight from Denver to Panama (average of $354). Flying from Denver to Panama in June is currently the most expensive (average of $520). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Vail to San José flights

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Denver to Tegucigalpa flights

Gunnison to Liberia flights

Montrose to Managua flights

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Cortez to San José flights

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Grand Junction to Managua flights

Durango to Managua flights

Top 4 airlines flying from Denver to Panama

Airline	Cheapest	Average	Flexibility	On-time
Copa Airlines	Cheapest$465	Average$641	FlexibilityNo cancel fee	On-time70%
Delta	Cheapest$527	Average$947	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$527	Average$650	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$527	Average$683	FlexibilityNo cancel fee	On-time69%

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$179+ Cheap flights from Denver (DEN) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/27. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Denver to Panama with Cheapflights

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Cheap flight deals from Denver to Panama

Cheapest flights from Denver to PanamaExplore the most affordable flight options available from Denver to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 2, 2026.

Explore the most affordable flight options available from Denver to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 2, 2026.

Find flight deals from Denver to Panama

Keep the following information in mind while searching for Denver to Panama flight deals. Data was last updated January 2, 2026.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Cheapflights Fare Finder

Use the filters below to find and compare flights from Denver to Panama that are best for you.

Best time to book a flight from Denver to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Denver with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Denver to Panama

What is the cheapest month to book a flight from Denver to Panama?

What is the cheapest time of day to fly from DEN to PA?

Find hourly flight availability from Denver to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 2, 2026.

Reviews of airlines servicing Panama

Get a feel of what it's like to fly with Delta, Copa Airlines, and United Airlines from Denver to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Denver to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Denver to Panama?

How popular is this Denver to Panama flight route?

How long is the flight from Denver to Panama?

What are the cheapest flights from Denver to Panama?

Can I find deals for flights from Denver to Panama that include hotel bookings?

How can I find direct flights from Denver to Panama?

Can I find deals for business class flights from Denver to Panama?

What is the cheapest month to book a flight from Denver to Panama?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Denver to Panama

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Denver to Panama

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Cheapest flights from Denver to Panama
Explore the most affordable flight options available from Denver to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 2, 2026.