$291+ Cheap flights from Denver (DEN) to Panama
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/21. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — PTY
Nov 19 — Nov 261
Round-trip
1 adult, Economy
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Find cheap flights from Denver to Panama with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
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Cheapest flights from Denver to PanamaExplore the most affordable flight options available from Denver to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 20, 2026.
Explore the most affordable flight options available from Denver to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 20, 2026.
This Copa Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/169:49 pm -
Nonstop5h 44m
Wed 11/1812:56 pm -
Nonstop6h 06m
Deal found 10/19![Copa Airlines logo]()
$649
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/211:59 pm -
1 stop12h 14m
Tue 2/92:26 pm -
1 stop10h 32m
Deal found 10/19![American Airlines logo]()
$656
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/38:00 am -
1 stop27h 59m
Sat 11/73:24 pm -
1 stop24h 05m
Deal found 10/18![Delta logo]()
$657
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/72:27 pm -
2 stops21h 46m
Fri 2/264:31 pm -
2 stops20h 59m
Deal found 10/15![American Airlines logo]()
$661
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/135:07 pm -
1 stop19h 00m
Fri 11/203:29 pm -
1 stop9h 46m
Deal found 10/18![Delta logo]()
$664
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/264:07 pm -
2 stops19h 55m
Mon 11/23:13 pm -
2 stops24h 34m
Deal found 10/19![American Airlines logo]()
$669
This Copa Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:50 pm -
Nonstop5h 43m
Mon 12/1412:56 pm -
Nonstop6h 14m
Deal found 10/18![Copa Airlines logo]()
$672
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/312:36 pm -
1 stop23h 37m
Mon 12/143:13 pm -
1 stop9h 47m
Deal found 10/19![American Airlines logo]()
$681
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2212:59 am -
1 stop11h 00m
Mon 11/23:24 pm -
1 stop9h 08m
Deal found 10/16![Delta logo]()
$684
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2211:53 pm -
1 stop12h 09m
Mon 10/262:02 pm -
2 stops22h 35m
Deal found 10/15![American Airlines logo]()
$689
This Super.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:43 pm -
Nonstop5h 50m
Sat 10/3112:56 pm -
Nonstop6h 15m
Deal found 10/16![Copa Airlines logo]()
$693
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/72:27 pm -
2 stops21h 46m
Sat 2/274:31 pm -
2 stops17h 39m
Deal found 10/15![American Airlines logo]()
$695
Best flights from Denver to PanamaDiscover carefully curated flight deals from Denver to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 20, 2026.
Discover carefully curated flight deals from Denver to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 20, 2026.
This Copa Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/279:50 pm -
1 stop7h 54m
Thu 2/117:51 pm -
1 stop23h 23m
Deal found 10/18![Copa Airlines logo]()
$608
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/295:00 pm -
1 stop17h 15m
Sun 2/73:20 pm -
1 stop9h 59m
Deal found 10/19![Delta logo]()
$664
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/198:39 pm -
1 stop16h 06m
Mon 3/297:55 am -
1 stop16h 32m
Deal found 10/15![United Airlines logo]()
$772
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2210:51 am -
2 stops43h 59m
Fri 11/279:48 am -
1 stop9h 14m
Deal found 10/16![Multiple Airlines logo]()
$1,148
This Copa Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/79:49 pm -
Nonstop5h 44m
Sat 11/1412:56 pm -
Nonstop6h 06m
Deal found 10/19![Copa Airlines logo]()
$649
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/155:00 pm -
1 stop17h 15m
Fri 1/223:20 pm -
1 stop9h 59m
Deal found 10/18![Delta logo]()
$664
This Copa Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/169:49 pm -
Nonstop5h 44m
Mon 11/2312:56 pm -
Nonstop6h 06m
Deal found 10/17![Copa Airlines logo]()
$649
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/85:00 am -
1 stop7h 45m
Sat 1/164:41 pm -
1 stop18h 20m
Deal found 10/18![United Airlines logo]()
$782
This Copa Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/289:50 pm -
Nonstop5h 43m
Tue 2/212:56 pm -
Nonstop6h 18m
Deal found 10/18![Copa Airlines logo]()
$649
This Copa Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/199:55 pm -
Nonstop5h 38m
Mon 3/112:56 pm -
Nonstop6h 19m
Deal found 10/19![Copa Airlines logo]()
$649
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/125:00 am -
1 stop12h 38m
Wed 12/308:55 am -
1 stop23h 43m
Deal found 10/17![United Airlines logo]()
$795
This Copa Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:50 pm -
Nonstop5h 43m
Mon 12/1412:56 pm -
Nonstop6h 14m
Deal found 10/19![Copa Airlines logo]()
$672
This Copa Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/229:49 pm -
1 stop7h 56m
Fri 11/279:48 am -
1 stop9h 14m
Deal found 10/18![Copa Airlines logo]()
$734
This United deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/278:33 pm -
2 stops34h 14m
Thu 2/117:51 pm -
2 stops22h 33m
Deal found 10/18![Multiple Airlines logo]()
$1,308
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/224:44 pm -
2 stops38h 06m
Fri 11/279:48 am -
2 stops25h 14m
Deal found 10/16![United Airlines logo]()
$1,757
Last-minute flights from Denver to PanamaDiscover last-minute flight deals from Denver to Panama. Data last updated October 20, 2026 and is based on user searches.
Discover last-minute flight deals from Denver to Panama. Data last updated October 20, 2026 and is based on user searches.
This Copa Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2210:43 pm -
Nonstop5h 50m
Mon 10/2612:56 pm -
Nonstop6h 15m
Deal found 10/15![Copa Airlines logo]()
$672
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2212:59 am -
1 stop11h 00m
Sat 10/312:24 pm -
1 stop9h 08m
Deal found 10/16![Delta logo]()
$684
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2211:53 pm -
1 stop12h 09m
Mon 10/262:02 pm -
2 stops22h 35m
Deal found 10/15![American Airlines logo]()
$689
This Super.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:43 pm -
Nonstop5h 50m
Sat 10/3112:56 pm -
Nonstop6h 15m
Deal found 10/16![Copa Airlines logo]()
$693
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2512:59 pm -
1 stop23h 00m
Mon 11/23:24 pm -
1 stop9h 08m
Deal found 10/16![Delta logo]()
$698
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/264:07 pm -
2 stops19h 55m
Mon 11/23:13 pm -
2 stops24h 34m
Deal found 10/19![American Airlines logo]()
$669
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/211:59 pm -
1 stop12h 14m
Tue 2/92:26 pm -
1 stop10h 32m
Deal found 10/19![American Airlines logo]()
$656
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/38:00 am -
1 stop27h 59m
Sat 11/73:24 pm -
1 stop24h 05m
Deal found 10/18![Delta logo]()
$657
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/72:27 pm -
2 stops21h 46m
Fri 2/264:31 pm -
2 stops20h 59m
Deal found 10/15![American Airlines logo]()
$661
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/72:27 pm -
2 stops21h 46m
Sat 2/274:31 pm -
2 stops17h 39m
Deal found 10/15![American Airlines logo]()
$695
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/135:07 pm -
1 stop19h 00m
Fri 11/203:29 pm -
1 stop9h 46m
Deal found 10/18![Delta logo]()
$664
This Copa Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/169:49 pm -
Nonstop5h 44m
Wed 11/1812:56 pm -
Nonstop6h 06m
Deal found 10/19![Copa Airlines logo]()
$649
One-way flights from Denver to PanamaSearch for one-way flight options from Denver to Panama. Find affordable one-way fares based on user searches. Data last updated October 20, 2026.
Search for one-way flight options from Denver to Panama. Find affordable one-way fares based on user searches. Data last updated October 20, 2026.
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2111:59 pm -
1 stop13h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![American Airlines logo]()
$291
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/2411:30 pm -
1 stop14h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![American Airlines logo]()
$296
This Kiwi.com deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/3112:18 pm -
1 stop23h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/15![Multiple Airlines logo]()
$318
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/86:59 pm -
2 stops18h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![American Airlines logo]()
$325
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/911:59 pm -
1 stop11h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/15![American Airlines logo]()
$351
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/102:50 pm -
1 stop11h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Multiple Airlines logo]()
$353
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/72:20 pm -
1 stop12h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Multiple Airlines logo]()
$356
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/412:59 am -
1 stop12h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![American Airlines logo]()
$358
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2412:18 pm -
1 stop17h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![Multiple Airlines logo]()
$380
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/912:18 pm -
1 stop23h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Multiple Airlines logo]()
$381
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/711:59 pm -
1 stop13h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/15![American Airlines logo]()
$385
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/58:40 pm -
3 stops44h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![Multiple Airlines logo]()
$444
Find flight deals from Denver to Panama
Keep the following information in mind while searching for Denver to Panama flight deals. Data was last updated October 20, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $608 (Copa Airlines) |
One-way from | $291 (American Airlines) |
Popular in | December |
Cheapest in | April |
Average price | $654 |
Good round-trip deal | $624 or less |
Good one-way deal | $338 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Denver to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 20, 2026.
Use the filters below to find and compare flights from Denver to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DenverPanama City
DEN Denver Intl - PTY Panama City Tocumen Intl
DENPTY
Denver Intl
Tue 2/16
11:30 pm-1:47 pm
1 stop12h 17m
Panama City Tocumen Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$291
DenverPanama City
DEN Denver Intl - PTY Panama City Tocumen Intl
DENPTY
Denver Intl
Tue 1/5
10:37 pm-5:17 pm
3 stops40h 40m
Panama City Tocumen Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$404
DenverPanama City
DEN Denver Intl - PTY Panama City Tocumen Intl
DENPTY
Denver Intl
Fri 11/6
3:30 pm-2:10 am
2 stops32h 40m
Panama City Tocumen Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$414
DenverDavid
DEN Denver Intl - DAV David Enrique Malek
DENDAV
Denver Intl
Sat 12/5
3:22 pm-6:58 pm
2 stops25h 36m
David Enrique Malek
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$526
DenverPanama City
DEN Denver Intl - PTY Panama City Tocumen Intl
DENPTY
Denver Intl
Tue 2/16
11:30 pm-1:20 am
3 stops23h 50m
Panama City Tocumen Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$560
DenverPanama City
DEN Denver Intl - PTY Panama City Tocumen Intl
DENPTY
Denver Intl
Sun 10/25
6:56 pm-1:20 am
3 stops29h 24m
Panama City Tocumen Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$572
DenverDavid
DEN Denver Intl - DAV David Enrique Malek
DENDAV
Denver Intl
Wed 1/27
9:50 pm-7:44 am
1 stop7h 54m
David Enrique Malek
Thu 2/11
7:51 pm-5:14 pm
1 stop23h 23m
$608
DenverPanama City
DEN Denver Intl - PTY Panama City Tocumen Intl
DENPTY
Denver Intl
Sat 11/7
9:49 pm-5:33 am
Nonstop5h 44m
Panama City Tocumen Intl
Sat 11/14
12:56 pm-5:02 pm
Nonstop6h 06m
$649
DenverPanama City
DEN Denver Intl - PTY Panama City Tocumen Intl
DENPTY
Denver Intl
Mon 11/16
9:49 pm-5:33 am
Nonstop5h 44m
Panama City Tocumen Intl
Mon 11/23
12:56 pm-5:02 pm
Nonstop6h 06m
$649
DenverPanama City
DEN Denver Intl - PTY Panama City Tocumen Intl
DENPTY
Denver Intl
Thu 1/28
9:50 pm-5:33 am
Nonstop5h 43m
Panama City Tocumen Intl
Tue 2/2
12:56 pm-5:14 pm
Nonstop6h 18m
$649
Showing 1-10 of 27 resultsSorted by cheapest first
Best time to book a flight from Denver to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from Denver with our price prediction graph.
DEN-PTY
DEN-DAV
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Denver to Panama
DEN-PA0
DEN-PTY
DEN-DAV
What is the cheapest month to book a flight from Denver to Panama?
Currently, May is the cheapest month in which you can book a flight from Denver to Panama (average of $607). Flying from Denver to Panama in December is currently the most expensive (average of $894). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DEN to PA?
Find hourly flight availability from Denver to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 20, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Denver to Panama as you normally would.
How far ahead should I book a flight from Denver to Panama?
To ensure you get the cheapest price possible for a flight from Denver to Panama, you should look to book at least 85 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated October 20, 2026.
Get a feel of what it's like to fly with Copa Airlines,United Airlines, andAmerican Airlines from Denver to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.6
Food
7.0
Entertainment
6.9
Crew
8.1
Boarding
7.8
Comfort
7.5
Reviews
1 / 20
2.0
MediocreAnonymous,Oct 2026
BOS - PTY
Overall
7.6
Food
7.0
Entertainment
6.9
Crew
8.1
Boarding
7.8
Comfort
7.5
Reviews
1 / 20
2.0
MediocreAnonymous,Oct 2026
BOS - PTY
Overall
7.6
Food
7.0
Entertainment
6.9
Crew
8.1
Boarding
7.8
Comfort
7.5
Reviews
1 / 20
2.0
MediocreAnonymous,Oct 2026
BOS - PTY
Overall
7.6
Food
7.0
Entertainment
6.9
Crew
8.1
Boarding
7.8
Comfort
7.5
Reviews
1 / 20
2.0
MediocreAnonymous,Oct 2026
BOS - PTY
Related info for your journey
Find useful and relevant information for your journey from Denver to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Denver to Panama
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Denver to Panama by cabin class
Find flights from Denver to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Denver and Panama flights
Browse other Denver and Panama flight options. Last updated on October 20, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Denver to Panama
Discover the top 3 airlines that operate flights from Denver to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 20, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$493 | Average$653 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$531 | Average$697 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$634 | Average$716 | FlexibilityNo cancel fee | On-time71% |