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$169+ Cheap flights from Denver (DEN) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/20. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — PTY
Aug 25 — Sep 11
Mon 8/25
Mon 9/1
1 adult, Economy
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Cheap flight deals from Denver to Panama

Keep the following information in mind while searching for Denver to Panama flight deals. Data was last updated August 20, 2025.

Round-trip from

$440
(Kiwi.com)

One-way from

$169
(Kiwi.com)

Popular in

December

Cheapest in

October

Average price

$574

Good round-trip deal

$439 or less

Good one-way deal

$172 or less
From Denver Intl to Panama
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One-way flight from Denver Intl to Panama
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Highest demand for flights based on searches. 5% potential increase in price ($37 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($15 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Price to beat on a round-trip flight from Denver Intl to Panama.
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Price to beat on a one-way flight from Denver Intl to Panama.
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Find flight deals from Denver to Panama

Cheapest flights from Denver to Panama
Explore the most affordable flight options available from Denver to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 20, 2025.

This Kiwi.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/46:55 pmDEN - PTY
1 stop12h 16mMultiple Airlines
Sat 10/118:10 amPTY - DEN
1 stop12h 58mMultiple Airlines
Deal found 8/20$440
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/176:55 pmDEN - PTY
1 stop12h 16mMultiple Airlines
Wed 9/249:33 pmPTY - DEN
1 stop11h 57mMultiple Airlines
Deal found 8/19$450
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1512:34 amDEN - PTY
1 stop14h 51mMultiple Airlines
Fri 10/249:33 pmPTY - DEN
1 stop12h 00mMultiple Airlines
Deal found 8/19$458
This Kiwi.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/196:55 pmDEN - PTY
1 stop14h 45mMultiple Airlines
Fri 9/269:33 pmPTY - DEN
1 stop12h 42mMultiple Airlines
Deal found 8/20$459
This Kiwi.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/116:55 pmDEN - PTY
1 stop12h 16mMultiple Airlines
Fri 9/269:33 pmPTY - DEN
1 stop12h 42mMultiple Airlines
Deal found 8/20$473
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1810:20 amDEN - PTY
1 stop9h 17mMultiple Airlines
Fri 10/249:33 pmPTY - DEN
1 stop12h 00mMultiple Airlines
Deal found 8/19$478
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/116:55 pmDEN - PTY
1 stop12h 16mMultiple Airlines
Thu 9/189:33 pmPTY - DEN
1 stop11h 57mMultiple Airlines
Deal found 8/18$481
This Kiwi.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/126:55 pmDEN - PTY
1 stop12h 16mMultiple Airlines
Sat 9/279:33 pmPTY - DEN
1 stop11h 57mMultiple Airlines
Deal found 8/20$484
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/176:36 pmDEN - PTY
1 stop9h 49mMultiple Airlines
Fri 10/245:25 pmPTY - DEN
2 stops16h 08mMultiple Airlines
Deal found 8/19$488
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1810:20 amDEN - PTY
1 stop9h 17mMultiple Airlines
Thu 10/239:33 pmPTY - DEN
1 stop12h 00mMultiple Airlines
Deal found 8/19$497

Cheapflights Fare Finder

 
Customize your flight search to find flights from Denver to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
Use the filters below to find and compare flights from Denver to Panama that are best for you.

Fly from

Denver

Fly to

Panama

Route

Depart

Return

Price

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 10/4

6:55 pm-8:11 am

1 stop12h 16m

Panama City Tocumen Intl

Sat 10/11

8:10 am-8:08 pm

1 stop12h 58m

$440

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 9/17

6:55 pm-8:11 am

1 stop12h 16m

Panama City Tocumen Intl

Wed 9/24

9:33 pm-8:30 am

1 stop11h 57m

$450

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 10/15

12:34 am-4:25 pm

1 stop14h 51m

Panama City Tocumen Intl

Fri 10/24

9:33 pm-8:33 am

1 stop12h 00m

$458

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 9/19

6:55 pm-10:40 am

1 stop14h 45m

Panama City Tocumen Intl

Fri 9/26

9:33 pm-9:15 am

1 stop12h 42m

$459

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 10/18

10:20 am-8:37 pm

1 stop9h 17m

Panama City Tocumen Intl

Fri 10/24

9:33 pm-8:33 am

1 stop12h 00m

$478

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 9/11

6:55 pm-8:11 am

1 stop12h 16m

Panama City Tocumen Intl

Thu 9/18

9:33 pm-8:30 am

1 stop11h 57m

$481

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 9/12

6:55 pm-8:11 am

1 stop12h 16m

Panama City Tocumen Intl

Sat 9/27

9:33 pm-8:30 am

1 stop11h 57m

$484

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 10/17

6:36 pm-5:25 am

1 stop9h 49m

Panama City Tocumen Intl

Fri 10/24

5:25 pm-8:33 am

2 stops16h 08m

$488

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 10/3

6:55 pm-8:11 am

1 stop12h 16m

Panama City Tocumen Intl

Sun 10/12

9:33 pm-8:33 am

1 stop12h 00m

$497

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 10/18

10:20 am-8:37 pm

1 stop9h 17m

Panama City Tocumen Intl

Thu 10/23

9:33 pm-8:33 am

1 stop12h 00m

$497

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/20

Showing 1-10 of 15 results
1
2

Best time to book a flight from Denver to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to Panama

What is the cheapest month to book a flight from Denver to Panama?

Currently, October is the cheapest month in which you can book a flight from Denver to Panama (average of $478). Flying from Denver to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to PA?

Find hourly flight availability from Denver to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Denver to Panama as you normally would.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated August 20, 2025.
Get a feel of what it's like to fly with Delta, Copa Airlines, and United Airlines from Denver to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,982 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,982 reviews
Delta
8.0
Very good
7,982 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Copa Airlines
7.5
Good
1,510 reviews
Delta
8.0
Very good
7,982 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,928 reviews
Delta
8.0
Very good
7,982 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,982 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Denver to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Denver to Panama?

    If you book a flight to Panama from Denver, you will be flying from Denver Intl, which is the city’s only airport. Denver Intl (DEN) is located 18.5 mi from the center of Denver.

  • How popular is this Denver to Panama flight route?

    Within the past month, 34 users have taken a look at flights from Denver Intl to Panama.

  • What are the cheapest flights from Denver to Panama?

    Looking at all options, your cheapest flight can be booked for $128. While the most popular route (Denver Intl - Panama City Tocumen Intl) can be booked for $450 on average our data indicates $761 when flying from Denver to Panama.

  • Can I find deals for flights from Denver to Panama that include hotel bookings?

    Yes. In addition to deals on Denver to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Panama.

  • Can I find deals for business class flights from Denver to Panama?

    Yes. Cheapflights offers flight deals from Denver to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to Panama?

    Currently, October is the cheapest month in which you can book a flight from Denver to Panama (average of $478). Flying from Denver to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Denver to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Grand Junction to Managua flights
Colorado Springs to Panama City flights
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Colorado Springs to Philip S.W.Goldson flights
Montrose to San José flights
Denver to Tegucigalpa flights
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Cortez to San José flights
Montrose to Managua flights
Montrose to San Salvador flights

Top 4 airlines flying from Denver to Panama

Discover the top 4 airlines that operate flights from Denver to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$473Average$645FlexibilityNo cancel feeOn-time70%
DeltaCheapest$491Average$683FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$491Average$642FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$527Average$699FlexibilityNo cancel feeOn-time69%

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