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$153+ Cheap flights from Denver (DEN) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/7. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — PTY
Nov 15 — Nov 221
Sat 11/15
Sat 11/22
1 adult, Economy
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Find flight deals from Denver to Panama

Cheapest flights from Denver to Panama
Explore the most affordable flight options available from Denver to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 16, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2912:34 amDEN - PTY
1 stop14h 32mMultiple Airlines
Thu 11/139:33 pmPTY - DEN
1 stop13h 00mMultiple Airlines
Deal found 10/15$477
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/212:34 amDEN - PTY
1 stop13h 20mMultiple Airlines
Fri 11/79:33 pmPTY - DEN
1 stop13h 00mMultiple Airlines
Deal found 10/14$513
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/212:34 amDEN - PTY
1 stop16h 46mMultiple Airlines
Wed 11/126:34 pmPTY - DEN
1 stop15h 59mMultiple Airlines
Deal found 10/14$528
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1212:34 amDEN - PTY
1 stop14h 02mMultiple Airlines
Thu 11/209:33 pmPTY - DEN
1 stop13h 30mMultiple Airlines
Deal found 10/14$533
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/311:14 pmDEN - PTY
1 stop9h 26mMultiple Airlines
Tue 12/99:33 pmPTY - DEN
1 stop13h 25mMultiple Airlines
Deal found 10/14$536
This Copa Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/99:36 pmDEN - PTY
Nonstop5h 57mCopa Airlines
Thu 1/1512:56 pmPTY - DEN
Nonstop6h 20mCopa Airlines
Deal found 10/14$548
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/38:00 amDEN - PTY
2 stops14h 40mMultiple Airlines
Mon 12/89:33 pmPTY - DEN
1 stop13h 25mMultiple Airlines
Deal found 10/14$550
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/411:14 pmDEN - PTY
1 stop9h 26mMultiple Airlines
Mon 12/89:33 pmPTY - DEN
1 stop13h 25mMultiple Airlines
Deal found 10/14$552

Cheap flight deals from Denver to Panama

Keep the following information in mind while searching for Denver to Panama flight deals. Data was last updated October 16, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$477
(Kiwi.com)

One-way from

$153
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$586

Good round-trip deal

$429 or less

Good one-way deal

$174 or less
Provider with most accurate pricing for Denver Intl-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Denver Intl-Panama City Tocumen Intl flights.
Search Deals
From Denver Intl to Panama
Search Deals
One-way flight from Denver Intl to Panama
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($38 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals
Price to beat on a round-trip flight from Denver Intl to Panama.
Search Deals
Price to beat on a one-way flight from Denver Intl to Panama.
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Denver to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from Denver to Panama that are best for you.

Fly from

Denver

Fly to

Panama

Route

Depart

Return

Price

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 2/28

9:38 pm-5:33 am

Nonstop5h 55m

Panama City Tocumen Intl

Sun 3/8

12:56 pm-6:16 pm

Nonstop6h 20m

$535

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 3/5

9:48 pm-5:33 am

Nonstop5h 45m

Panama City Tocumen Intl

Mon 3/9

12:56 pm-6:16 pm

Nonstop6h 20m

$535

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 1/16

9:38 pm-5:33 am

Nonstop5h 55m

Panama City Tocumen Intl

Thu 1/29

12:56 pm-5:16 pm

Nonstop6h 20m

$535

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 1/9

9:38 pm-5:33 am

Nonstop5h 55m

Panama City Tocumen Intl

Sun 1/18

12:56 pm-5:16 pm

Nonstop6h 20m

$548

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 1/1

9:38 pm-5:33 am

Nonstop5h 55m

Panama City Tocumen Intl

Sun 1/18

12:56 pm-5:16 pm

Nonstop6h 20m

$548

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 2/28

5:00 am-7:38 pm

1 stop12h 38m

Panama City Tocumen Intl

Fri 3/6

4:41 pm-11:40 pm

1 stop8h 59m

$550

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Mon 3/23

12:59 am-12:55 pm

1 stop10h 56m

Panama City Tocumen Intl

Tue 3/31

2:20 pm-11:54 pm

1 stop10h 34m

$550

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 1/31

8:32 pm-5:07 pm

1 stop18h 35m

Panama City Tocumen Intl

Fri 2/6

4:41 pm-8:55 am

1 stop18h 14m

$550

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 2/11

7:20 pm-2:45 pm

1 stop17h 25m

Panama City Tocumen Intl

Mon 2/16

8:55 am-9:23 pm

1 stop14h 28m

$550

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 2/27

5:00 am-5:07 pm

1 stop10h 07m

Panama City Tocumen Intl

Fri 3/6

4:41 pm-11:40 pm

1 stop8h 59m

$550

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/14

Showing 1-10 of 18 results
1
2

Best time to book a flight from Denver to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to Panama

What is the cheapest month to book a flight from Denver to Panama?

Currently, March is the cheapest month in which you can book a flight from Denver to Panama (average of $354). Flying from Denver to Panama in June is currently the most expensive (average of $520). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to PA?

Find hourly flight availability from Denver to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 16, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 54% on flights from Denver to Panama by exploring options for tickets at noon.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated October 16, 2025.
Get a feel of what it's like to fly with Delta, Copa Airlines, and United Airlines from Denver to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,979 reviews

Boarding

8.2

Crew

8.5

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
8.0
Very good
7,979 reviews
Delta
8.0
Very good
7,979 reviews

Boarding

8.2

Crew

8.5

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Copa Airlines
7.6
Good
1,549 reviews
Delta
8.0
Very good
7,979 reviews

Boarding

8.2

Crew

8.5

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,979 reviews
Delta
8.0
Very good
7,979 reviews

Boarding

8.2

Crew

8.5

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,041 reviews
Delta
8.0
Very good
7,979 reviews

Boarding

8.2

Crew

8.5

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Denver to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Denver to Panama?

    If you book a flight to Panama from Denver, you will be flying from Denver Intl, which is the city’s only airport. Denver Intl (DEN) is located 18.5 mi from the center of Denver.

  • How popular is this Denver to Panama flight route?

    Within the past month, 29 users have taken a look at flights from Denver Intl to Panama.

  • How long is the flight from Denver to Panama?

    Departing from Denver to Panama will take you 5h 45m. The distance from Denver to Panama is about 2634 mi. Most flights are nonstop.

  • What are the cheapest flights from Denver to Panama?

    Looking at all options, your cheapest flight can be booked for $138. While the most popular route (Denver Intl - Panama City Tocumen Intl) can be booked for $535 on average, our data indicates $811 when flying from Denver to Panama.

  • Can I find deals for flights from Denver to Panama that include hotel bookings?

    Yes. In addition to deals on Denver to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Panama.

  • Can I find deals for business class flights from Denver to Panama?

    Yes. Cheapflights offers flight deals from Denver to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to Panama?

    Currently, March is the cheapest month in which you can book a flight from Denver to Panama (average of $354). Flying from Denver to Panama in June is currently the most expensive (average of $520). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Denver to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Gunnison to San Salvador flights
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Gunnison to Liberia flights
Durango to Coxen Hole flights
Denver to San Pedro Town flights
Colorado Springs to Panama City flights
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Cortez to San José flights
Denver to Tegucigalpa flights

Top 4 airlines flying from Denver to Panama

Discover the top 4 airlines that operate flights from Denver to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$489Average$661FlexibilityNo cancel feeOn-time70%
DeltaCheapest$518Average$924FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$527Average$667FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$527Average$689FlexibilityNo cancel feeOn-time69%

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