$267+ Cheap flights from Denver (DEN) to Panama
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/15. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — PTY
Jul 18 — Jul 251
Round-trip
1 adult, Economy
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Cheapest flights from Denver to PanamaExplore the most affordable flight options available from Denver to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 18, 2026.
Explore the most affordable flight options available from Denver to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 18, 2026.
This Copa Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/19:49 pm
DEN
- PTY
Nonstop5h 44m
Copa Airlines
Thu 11/512:56 pm
PTY
- DEN
Nonstop6h 06m
Copa Airlines
Deal found 6/13![Copa Airlines logo]()
$510
This Copa Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1910:43 pm
DEN
- PTY
Nonstop5h 50m
Copa Airlines
Wed 8/2612:56 pm
PTY
- DEN
Nonstop6h 24m
Copa Airlines
Deal found 6/13![Copa Airlines logo]()
$520
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:00 am
DEN
- PTY
1 stop12h 37m
United Airlines
Tue 9/2210:00 am
PTY
- DEN
1 stop9h 19m
United Airlines
Deal found 6/14![United Airlines logo]()
$525
This Copa Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:49 pm
DEN
- PTY
Nonstop5h 44m
Copa Airlines
Sun 11/2212:56 pm
PTY
- DEN
Nonstop6h 06m
Copa Airlines
Deal found 6/16![Copa Airlines logo]()
$528
This American Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/175:46 pm
DEN
- PTY
2 stops19h 14m
American Airlines
Sat 11/72:43 pm
PTY
- DEN
2 stops21h 10m
American Airlines
Deal found 6/17![American Airlines logo]()
$529
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/311:55 pm
DEN
- PTY
1 stop11h 44m
American Airlines
Sat 9/121:16 pm
PTY
- DEN
1 stop10h 09m
American Airlines
Deal found 6/14![American Airlines logo]()
$530
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1511:55 pm
DEN
- PTY
1 stop11h 44m
American Airlines
Thu 10/223:35 pm
PTY
- DEN
2 stops21h 14m
American Airlines
Deal found 6/16![American Airlines logo]()
$534
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/158:31 pm
DEN
- PTY
1 stop16h 43m
United Airlines
Sat 8/223:30 pm
PTY
- DEN
1 stop8h 38m
United Airlines
Deal found 6/15![United Airlines logo]()
$535
This Copa Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/310:43 pm
DEN
- PTY
Nonstop5h 50m
Copa Airlines
Sat 9/1212:56 pm
PTY
- DEN
Nonstop6h 15m
Copa Airlines
Deal found 6/16![Copa Airlines logo]()
$538
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/154:21 pm
DEN
- PTY
2 stops19h 18m
American Airlines
Sat 9/51:39 pm
PTY
- DEN
2 stops21h 07m
American Airlines
Deal found 6/16![American Airlines logo]()
$539
This American Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:46 pm
DEN
- PTY
2 stops19h 14m
American Airlines
Thu 10/293:35 pm
PTY
- DEN
1 stop31h 26m
American Airlines
Deal found 6/17![American Airlines logo]()
$543
This American Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1211:59 pm
DEN
- PTY
1 stop11h 17m
American Airlines
Sat 9/261:16 pm
PTY
- DEN
1 stop23h 57m
American Airlines
Deal found 6/17![American Airlines logo]()
$544
Best flights from Denver to PanamaDiscover carefully curated flight deals from Denver to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 18, 2026.
Discover carefully curated flight deals from Denver to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 18, 2026.
This United Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:00 am
DEN
- PTY
1 stop12h 37m
United Airlines
Wed 9/2310:00 am
PTY
- DEN
1 stop11h 09m
United Airlines
Deal found 6/13![United Airlines logo]()
$525
This Copa Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:49 pm
DEN
- PTY
Nonstop5h 44m
Copa Airlines
Sun 11/2212:56 pm
PTY
- DEN
Nonstop6h 06m
Copa Airlines
Deal found 6/13![Copa Airlines logo]()
$528
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:34 pm
DEN
- PTY
1 stop16h 40m
United Airlines
Sun 10/1110:00 am
PTY
- DEN
1 stop13h 15m
United Airlines
Deal found 6/16![United Airlines logo]()
$525
This Copa Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/310:43 pm
DEN
- PTY
Nonstop5h 50m
Copa Airlines
Sat 9/1212:56 pm
PTY
- DEN
Nonstop6h 15m
Copa Airlines
Deal found 6/17![Copa Airlines logo]()
$538
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:34 pm
DEN
- PTY
1 stop16h 40m
United Airlines
Tue 10/1310:00 am
PTY
- DEN
1 stop11h 08m
United Airlines
Deal found 6/14![United Airlines logo]()
$525
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/287:40 am
DEN
- PTY
1 stop9h 57m
United Airlines
Sun 9/133:30 pm
PTY
- DEN
1 stop17h 32m
United Airlines
Deal found 6/14![United Airlines logo]()
$535
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/38:31 pm
DEN
- PTY
1 stop16h 43m
United Airlines
Sat 9/123:30 pm
PTY
- DEN
1 stop16h 17m
United Airlines
Deal found 6/15![United Airlines logo]()
$535
This Copa Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/310:43 pm
DEN
- PTY
Nonstop5h 50m
Copa Airlines
Wed 8/1912:56 pm
PTY
- DEN
Nonstop6h 24m
Copa Airlines
Deal found 6/13![Copa Airlines logo]()
$667
This Copa Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/2610:42 pm
DEN
- PTY
Nonstop5h 50m
Copa Airlines
Mon 8/312:56 pm
PTY
- DEN
Nonstop6h 24m
Copa Airlines
Deal found 6/17![Copa Airlines logo]()
$688
This United Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/118:39 pm
DEN
- PTY
1 stop16h 06m
United Airlines
Sun 11/224:41 pm
PTY
- DEN
1 stop8h 46m
United Airlines
Deal found 6/17![United Airlines logo]()
$640
Last-minute flights from Denver to PanamaDiscover last-minute flight deals from Denver to Panama. Data last updated June 18, 2026 and is based on user searches.
Discover last-minute flight deals from Denver to Panama. Data last updated June 18, 2026 and is based on user searches.
This Orbitz deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/711:59 pm
DEN
- PTY
2 stops48h 56m
Multiple Airlines
Wed 7/223:50 pm
PTY
- DEN
2 stops32h 09m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$690
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:00 am
DEN
- PTY
1 stop10h 12m
United Airlines
Wed 7/227:55 am
PTY
- DEN
1 stop15h 20m
United Airlines
Deal found 6/16![United Airlines logo]()
$729
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1311:45 pm
DEN
- PTY
1 stop11h 29m
American Airlines
Mon 7/271:14 pm
PTY
- DEN
2 stops23h 30m
American Airlines
Deal found 6/14![American Airlines logo]()
$707
This Travelocity deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1511:59 pm
DEN
- PTY
2 stops33h 31m
Multiple Airlines
Wed 7/223:50 pm
PTY
- DEN
2 stops22h 21m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$700
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/215:00 am
DEN
- PTY
1 stop10h 12m
United Airlines
Sun 7/2610:00 am
PTY
- DEN
1 stop13h 15m
United Airlines
Deal found 6/16![United Airlines logo]()
$703
This Copa Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/2610:42 pm
DEN
- PTY
Nonstop5h 50m
Copa Airlines
Mon 8/312:56 pm
PTY
- DEN
Nonstop6h 24m
Copa Airlines
Deal found 6/17![Copa Airlines logo]()
$688
This United Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/267:42 am
DEN
- PTY
1 stop7h 30m
United Airlines
Mon 8/37:55 am
PTY
- DEN
1 stop11h 28m
United Airlines
Deal found 6/17![United Airlines logo]()
$713
This American Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2911:45 pm
DEN
- PTY
1 stop11h 29m
American Airlines
Sat 8/81:39 pm
PTY
- DEN
2 stops21h 00m
American Airlines
Deal found 6/17![American Airlines logo]()
$697
This deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/3012:40 am
DEN
- PTY
1 stop11h 25m
Delta
Sun 8/162:20 pm
PTY
- DEN
1 stop11h 16m
Delta
Deal found 6/13![Delta logo]()
$719
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3110:07 am
DEN
- PTY
1 stop7h 30m
United Airlines
Mon 8/107:55 am
PTY
- DEN
1 stop11h 28m
United Airlines
Deal found 6/16![United Airlines logo]()
$693
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3111:45 pm
DEN
- PTY
1 stop11h 29m
American Airlines
Sun 8/91:39 pm
PTY
- DEN
2 stops23h 14m
American Airlines
Deal found 6/14![American Airlines logo]()
$702
This Copa Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3110:42 pm
DEN
- PTY
Nonstop5h 50m
Copa Airlines
Sun 8/912:56 pm
PTY
- DEN
Nonstop6h 24m
Copa Airlines
Deal found 6/16![Copa Airlines logo]()
$718
One-way flights from Denver to PanamaSearch for one-way flight options from Denver to Panama. Find affordable one-way fares based on user searches. Data last updated June 18, 2026.
Search for one-way flight options from Denver to Panama. Find affordable one-way fares based on user searches. Data last updated June 18, 2026.
This Expedia deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/151:59 pm
DEN
- PTY
2 stops19h 31m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$267
This Expedia deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/281:59 pm
DEN
- PTY
3 stops23h 56m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/151:53 pm
DEN
- PTY
3 stops33h 42m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/121:53 pm
DEN
- PTY
3 stops33h 42m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$313
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/811:40 pm
DEN
- PTY
1 stop15h 26m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$324
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2911:40 pm
DEN
- PTY
1 stop18h 40m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$334
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/911:59 pm
DEN
- PTY
1 stop18h 21m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$336
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2211:42 pm
DEN
- PTY
2 stops19h 55m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$345
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/153:10 pm
DEN
- PAC
3 stops26h 20m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$869
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1412:24 pm
DEN
- PAC
3 stops26h 06m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$1,385
Find flight deals from Denver to Panama
Keep the following information in mind while searching for Denver to Panama flight deals. Data was last updated June 18, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $510 (Copa Airlines) |
One-way from | $267 (Expedia) |
Popular in | December |
Cheapest in | April |
Average price | $670 |
Good round-trip deal | $534 or less |
Good one-way deal | $315 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Denver to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2026.
Use the filters below to find and compare flights from Denver to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Fri 9/11
5:00 am-6:37 pm
1 stop12h 37m
Panama City Tocumen Intl
Wed 9/23
10:00 am-8:09 pm
1 stop11h 09m
$525
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Thu 10/1
8:34 pm-2:14 pm
1 stop16h 40m
Panama City Tocumen Intl
Sun 10/11
10:00 am-10:15 pm
1 stop13h 15m
$525
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Fri 10/9
8:34 pm-2:14 pm
1 stop16h 40m
Panama City Tocumen Intl
Tue 10/13
10:00 am-8:08 pm
1 stop11h 08m
$525
Quickest round-trip
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Wed 11/11
9:49 pm-5:33 am
Nonstop5h 44m
Panama City Tocumen Intl
Sun 11/22
12:56 pm-5:02 pm
Nonstop6h 06m
$528
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Fri 8/28
7:40 am-6:37 pm
1 stop9h 57m
Panama City Tocumen Intl
Sun 9/13
3:30 pm-8:02 am
1 stop17h 32m
$535
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Thu 9/3
8:31 pm-2:14 pm
1 stop16h 43m
Panama City Tocumen Intl
Sat 9/12
3:30 pm-6:47 am
1 stop16h 17m
$535
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Thu 9/3
10:43 pm-5:33 am
Nonstop5h 50m
Panama City Tocumen Intl
Sat 9/12
12:56 pm-6:11 pm
Nonstop6h 15m
$538
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Wed 11/11
8:39 pm-2:45 pm
1 stop16h 06m
Panama City Tocumen Intl
Sun 11/22
4:41 pm-11:27 pm
1 stop8h 46m
$640
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Mon 8/3
10:43 pm-5:33 am
Nonstop5h 50m
Panama City Tocumen Intl
Wed 8/19
12:56 pm-6:20 pm
Nonstop6h 24m
$667
DenverPanama City
DEN - PTY
DENPTY
Denver Intl
Sun 7/26
10:42 pm-5:32 am
Nonstop5h 50m
Panama City Tocumen Intl
Mon 8/3
12:56 pm-6:20 pm
Nonstop6h 24m
$688
Showing 1-10 of 21 resultsSorted by cheapest first
Best time to book a flight from Denver to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from Denver with our price prediction graph.
DEN-PTY
DEN-PAC
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Denver to Panama
DEN-PA0
DEN-PTY
DEN-PAC
What is the cheapest month to book a flight from Denver to Panama?
Currently, March is the cheapest month in which you can book a flight from Denver to Panama (average of $234). Flying from Denver to Panama in July is currently the most expensive (average of $527). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DEN to PA?
Find hourly flight availability from Denver to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 18, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Denver to Panama as you normally would.
How far ahead should I book a flight from Denver to Panama?
To ensure you get the cheapest price possible for a flight from Denver to Panama, you should look to book at least 67 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated June 18, 2026.
Get a feel of what it's like to fly with Copa Airlines,United Airlines, andAmerican Airlines from Denver to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.9
Crew
8.1
Entertainment
6.8
Comfort
7.4
Boarding
7.8
Overall
7.6
Reviews
1 / 20
10.0
ExcellentAnonymous,Apr 2026
LIM - PTY
Food
6.9
Crew
8.1
Entertainment
6.8
Comfort
7.4
Boarding
7.8
Overall
7.6
Reviews
1 / 20
10.0
ExcellentAnonymous,Apr 2026
LIM - PTY
Food
6.9
Crew
8.1
Entertainment
6.8
Comfort
7.4
Boarding
7.8
Overall
7.6
Reviews
1 / 20
10.0
ExcellentAnonymous,Apr 2026
LIM - PTY
Food
6.9
Crew
8.1
Entertainment
6.8
Comfort
7.4
Boarding
7.8
Overall
7.6
Reviews
1 / 20
10.0
ExcellentAnonymous,Apr 2026
LIM - PTY
Related info for your journey
Find useful and relevant information for your journey from Denver to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Denver to Panama
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Denver to Panama by cabin class
Find flights from Denver to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Denver and Panama flights
Browse other Denver and Panama flight options. Last updated on June 18, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Denver to Panama
Discover the top 3 airlines that operate flights from Denver to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$464 | Average$632 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$527 | Average$683 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$634 | Average$743 | FlexibilityNo cancel fee | On-time71% |