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Palermo

$221+ Cheap flights from Irvine, CA to Palermo (PMO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/10. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — PMO
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheapflights Tip: The best prices from Irvine to Palermo Punta Raisi are usually found in March or November, booked 48 days in advance, depart on a Monday or Wednesday and return on a Sunday

Cheap flight deals from Irvine to Palermo

Keep the following information in mind while searching for Irvine to Palermo flight deals. Data was last updated September 16, 2025.

Round-trip from

$534
(Mytrip)

One-way from

$221
(Kiwi.com)

Popular in

June

Cheapest in

March

Average price

$855
From Irvine to Palermo Punta Raisi
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One-way flight from Irvine to Palermo Punta Raisi
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Highest demand for flights based on searches. 15% potential increase in price ($172 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($33 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Irvine to Palermo

Cheapest flights from Irvine to Palermo
Explore the most affordable flight options available from Irvine to Palermo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Mytrip deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/315:15 pmLAX - PMO
1 stop21h 35mMultiple Airlines
Fri 11/76:00 amPMO - LAX
1 stop18h 15mMultiple Airlines
Deal found 9/16$534
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/32:30 pmLAX - PMO
1 stop18h 10mMultiple Airlines
Wed 11/57:00 pmPMO - LAX
1 stop24h 55mMultiple Airlines
Deal found 9/15$549
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/32:30 pmLAX - PMO
1 stop16h 05mMultiple Airlines
Fri 11/76:00 amPMO - LAX
1 stop18h 15mMultiple Airlines
Deal found 9/15$572
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/32:30 pmLAX - PMO
1 stop15h 00mMultiple Airlines
Thu 11/67:00 pmPMO - LAX
1 stop29h 15mMultiple Airlines
Deal found 9/15$579
This Trip.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/231:00 pmLAX - PMO
1 stop25h 10mMultiple Airlines
Thu 11/67:00 pmPMO - LAX
1 stop29h 15mMultiple Airlines
Deal found 9/14$585
This FlightHub deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/23:20 pmLAX - PMO
1 stop22h 40mITA Airways
Sat 11/82:25 pmPMO - LAX
1 stop32h 05mITA Airways
Deal found 9/15$613
This Ovago deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/135:05 pmLAX - PMO
1 stop33h 40mBritish Airways
Mon 10/207:55 pmPMO - LAX
2 stops30h 22mBritish Airways
Deal found 9/15$617
This FlightHub deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/297:55 pmLAX - PMO
1 stop37h 20mTurkish Airlines
Thu 10/99:20 amPMO - LAX
1 stop35h 25mTurkish Airlines
Deal found 9/15$625
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/32:30 pmLAX - PMO
1 stop16h 05mMultiple Airlines
Sun 11/98:00 pmPMO - LAX
1 stop25h 30mMultiple Airlines
Deal found 9/15$646
This FlightHub deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/133:15 pmLAX - PMO
1 stop22h 15mITA Airways
Mon 10/2012:55 pmPMO - LAX
1 stop33h 20mITA Airways
Deal found 9/14$647

Cheapflights Fare Finder

 
Customize your flight search to find flights from Irvine to Palermo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Irvine to Palermo that are best for you.

Fly from

Irvine

Fly to

Palermo

Route

Depart

Return

Price

Los AngelesPalermo

LAX - PMO

LAXPMO

Los Angeles

Mon 10/13

5:05 pm-11:45 am

1 stop33h 40m

Palermo Punta Raisi

Mon 10/20

7:55 pm-5:17 pm

2 stops30h 22m

$617

Los AngelesPalermo

LAX - PMO

LAXPMO

Los Angeles

Mon 9/29

7:55 pm-6:15 pm

1 stop37h 20m

Palermo Punta Raisi

Thu 10/9

9:20 am-11:45 am

1 stop35h 25m

$625

Los AngelesPalermo

LAX - PMO

LAXPMO

Los Angeles

Mon 10/13

3:15 pm-10:30 pm

1 stop22h 15m

Palermo Punta Raisi

Mon 10/20

12:55 pm-1:15 pm

1 stop33h 20m

$647

Los AngelesPalermo

LAX - PMO

LAXPMO

Los Angeles

Fri 2/20

3:20 pm-2:30 pm

1 stop14h 10m

Palermo Punta Raisi

Tue 2/24

7:05 pm-1:30 pm

1 stop27h 25m

$655

Los AngelesPalermo

LAX - PMO

LAXPMO

Los Angeles

Wed 10/22

7:35 pm-8:55 am

1 stop28h 20m

Palermo Punta Raisi

Sun 11/2

7:10 pm-4:35 pm

1 stop30h 25m

$658

Los AngelesPalermo

LAX - PMO

LAXPMO

Los Angeles

Mon 11/24

6:45 pm-5:45 pm

1 stop38h 00m

Palermo Punta Raisi

Mon 12/1

9:30 am-4:50 pm

1 stop40h 20m

$662

Los AngelesPalermo

LAX - PMO

LAXPMO

Los Angeles

Fri 10/10

7:45 pm-3:15 pm

1 stop34h 30m

$221

Los AngelesPalermo

LAX - PMO

LAXPMO

Los Angeles

Wed 10/8

7:45 pm-11:10 pm

1 stop18h 25m

$228

Los AngelesPalermo

LAX - PMO

LAXPMO

Los Angeles

Sat 10/11

10:30 pm-2:05 pm

1 stop30h 35m

$239

Los AngelesPalermo

LAX - PMO

LAXPMO

Los Angeles

Sun 10/5

7:45 pm-11:10 pm

1 stop18h 25m

$242

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 12 results
1
2

Best time to book a flight from Irvine to Palermo

Have a flexible travel schedule? Discover the best time to fly to Palermo from Irvine with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Irvine to Palermo

How far ahead should I book a flight from Irvine to Palermo?

Use this chart to determine the optimal time to book a round-trip flight from Irvine to Palermo. Price data was last updated on September 12, 2025.

The price you pay for your flight from Irvine to Palermo may vary depending on when you book. For the best chance of a lower fare, look to book 46 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Irvine to Palermo?

Currently, January is the cheapest month in which you can book a flight from Irvine to Palermo (average of $758). Flying from Irvine to Palermo in June is currently the most expensive (average of $1,196). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IR9 to PMO?

Find hourly flight availability from Irvine to Palermo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Irvine to Palermo as you normally would.

Reviews of airlines servicing Palermo

Get insights into the airlines that provide service to Palermo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Palermo. Reviews last updated September 16, 2025.
Read reviews from past customers who have flown SWISS, Turkish Airlines, and Lufthansa from Irvine to Palermo. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
SWISS
7.6
Good
1,737 reviews

Boarding

7.7

Overall

7.6

Crew

8.2

Entertainment

6.8

Food

7.1

Comfort

7.4

Reviews

1 / 20
10.0
Excellent

Leonardo,Aug 2025

AMS - ZRH

Amazing alternative from Europe to Hong Kong. Quick connection (even with a non-European passport) and friendly staff that helped me and my family.
SWISS
7.6
Good
1,737 reviews
SWISS
7.6
Good
1,737 reviews

Boarding

7.7

Overall

7.6

Crew

8.2

Entertainment

6.8

Food

7.1

Comfort

7.4

Reviews

1 / 20
10.0
Excellent

Leonardo,Aug 2025

AMS - ZRH

Amazing alternative from Europe to Hong Kong. Quick connection (even with a non-European passport) and friendly staff that helped me and my family.
Turkish Airlines
7.3
Good
3,968 reviews
SWISS
7.6
Good
1,737 reviews

Boarding

7.7

Overall

7.6

Crew

8.2

Entertainment

6.8

Food

7.1

Comfort

7.4

Reviews

1 / 20
10.0
Excellent

Leonardo,Aug 2025

AMS - ZRH

Amazing alternative from Europe to Hong Kong. Quick connection (even with a non-European passport) and friendly staff that helped me and my family.
Lufthansa
6.8
Okay
7,407 reviews
SWISS
7.6
Good
1,737 reviews

Boarding

7.7

Overall

7.6

Crew

8.2

Entertainment

6.8

Food

7.1

Comfort

7.4

Reviews

1 / 20
10.0
Excellent

Leonardo,Aug 2025

AMS - ZRH

Amazing alternative from Europe to Hong Kong. Quick connection (even with a non-European passport) and friendly staff that helped me and my family.
ITA Airways
6.7
Okay
1,036 reviews
SWISS
7.6
Good
1,737 reviews

Boarding

7.7

Overall

7.6

Crew

8.2

Entertainment

6.8

Food

7.1

Comfort

7.4

Reviews

1 / 20
10.0
Excellent

Leonardo,Aug 2025

AMS - ZRH

Amazing alternative from Europe to Hong Kong. Quick connection (even with a non-European passport) and friendly staff that helped me and my family.
British Airways
6.7
Okay
7,363 reviews
SWISS
7.6
Good
1,737 reviews

Boarding

7.7

Overall

7.6

Crew

8.2

Entertainment

6.8

Food

7.1

Comfort

7.4

Reviews

1 / 20
10.0
Excellent

Leonardo,Aug 2025

AMS - ZRH

Amazing alternative from Europe to Hong Kong. Quick connection (even with a non-European passport) and friendly staff that helped me and my family.

Related info for your journey

Find useful and relevant information for your journey from Irvine to Palermo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Palermo from Irvine?

    Palermo Punta Raisi (PMO), located 15.2 mi from the city center, is the airport you fly into when you book flights from Irvine to Palermo. 6 airlines have flights to Punta Raisi from Irvine on a regular basis. Booking flights from Irvine to Palermo Punta Raisi should not be difficult; the airport handles an average of 0 inbound flights from Irvine per day.

  • How long is the flight from Irvine to Palermo?

    A quick flight from Irvine to Palermo can take about 22h 15m. British Airways provides one of the quickest options available for as low as $647. There are 6559 mi between Irvine and Palermo. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Irvine to Palermo that include hotel bookings?

    Yes. In addition to deals on Irvine to Palermo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Irvine to Palermo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Irvine to Palermo.

  • Can I find deals for business class flights from Irvine to Palermo?

    Yes. Cheapflights offers flight deals from Irvine to Palermo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Irvine to Palermo?

    Currently, January is the cheapest month in which you can book a flight from Irvine to Palermo (average of $758). Flying from Irvine to Palermo in June is currently the most expensive (average of $1,196). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Palermo?

Book flights to Palermo if you plan to visit one of these locations
Agrigento
Cefalù

Browse thousands of different options on Cheapflights for your next trip

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Top 6 airlines flying from Irvine to Palermo

Discover the top 6 airlines that operate flights from Irvine to Palermo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
SWISSCheapest$553Average$1,070FlexibilityNo cancel feeOn-time79%
DeltaCheapest$631Average$1,034FlexibilityNo cancel feeOn-timeN/A
ITA AirwaysCheapest$632Average$941FlexibilityNo cancel feeOn-time81%
British AirwaysCheapest$640Average$871FlexibilityNo cancel feeOn-time70%
LufthansaCheapest$717Average$913FlexibilityNo cancel feeOn-time76%
Turkish AirlinesCheapest$758Average$855FlexibilityNo cancel feeOn-time77%

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