$129+ Cheap flights from San Antonio (SAT) to Odessa, TX
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/21. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — MAF
Mar 12 — Mar 191
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from San Antonio to OdessaExplore the most affordable flight options available from San Antonio to Odessa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 10, 2026.
Explore the most affordable flight options available from San Antonio to Odessa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 10, 2026.
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/135:00 am
SAT
- MAF
1 stop3h 48m
American Airlines
Tue 3/175:00 am
MAF
- SAT
1 stop9h 25m
American Airlines
Deal found 2/9![American Airlines logo]()
$299
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/105:00 am
SAT
- MAF
1 stop3h 48m
American Airlines
Tue 3/249:18 am
MAF
- SAT
1 stop13h 36m
American Airlines
Deal found 2/8![American Airlines logo]()
$304
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/135:00 am
SAT
- MAF
1 stop3h 48m
American Airlines
Sat 3/212:30 pm
MAF
- SAT
1 stop8h 37m
American Airlines
Deal found 2/8![American Airlines logo]()
$311
This Southwest deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1012:50 pm
SAT
- MAF
1 stop5h 35m
Southwest
Tue 3/2411:00 am
MAF
- SAT
2 stops4h 40m
Southwest
Deal found 2/8![Southwest logo]()
$324
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/95:50 pm
SAT
- MAF
1 stop4h 00m
United Airlines
Mon 3/165:25 pm
MAF
- SAT
1 stop5h 32m
United Airlines
Deal found 2/9![United Airlines logo]()
$337
This Southwest deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/95:20 pm
SAT
- MAF
2 stops7h 00m
Southwest
Mon 3/165:20 am
MAF
- SAT
1 stop3h 20m
Southwest
Deal found 2/9![Southwest logo]()
$342
This Southwest deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/135:35 am
SAT
- MAF
1 stop4h 30m
Southwest
Tue 3/177:55 am
MAF
- SAT
2 stops5h 45m
Southwest
Deal found 2/9![Southwest logo]()
$352
This Southwest deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/135:35 am
SAT
- MAF
1 stop4h 30m
Southwest
Sat 3/214:20 pm
MAF
- SAT
2 stops7h 35m
Southwest
Deal found 2/8![Southwest logo]()
$361
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/277:45 pm
SAT
- MAF
1 stop3h 10m
Southwest
Fri 4/310:45 am
MAF
- SAT
1 stop3h 40m
Southwest
Deal found 2/10![Southwest logo]()
$375
Best flights from San Antonio to OdessaDiscover carefully curated flight deals from San Antonio to Odessa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 10, 2026.
Discover carefully curated flight deals from San Antonio to Odessa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 10, 2026.
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/135:00 am
SAT
- MAF
1 stop3h 48m
American Airlines
Tue 3/175:00 am
MAF
- SAT
1 stop9h 25m
American Airlines
Deal found 2/9![American Airlines logo]()
$299
This Southwest deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1012:50 pm
SAT
- MAF
1 stop5h 35m
Southwest
Tue 3/2411:00 am
MAF
- SAT
2 stops4h 40m
Southwest
Deal found 2/8![Southwest logo]()
$324
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/95:50 pm
SAT
- MAF
1 stop4h 00m
United Airlines
Mon 3/165:25 pm
MAF
- SAT
1 stop5h 32m
United Airlines
Deal found 2/9![United Airlines logo]()
$337
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/105:00 am
SAT
- MAF
1 stop3h 48m
American Airlines
Tue 3/249:18 am
MAF
- SAT
1 stop13h 36m
American Airlines
Deal found 2/8![American Airlines logo]()
$304
This Southwest deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/95:20 pm
SAT
- MAF
1 stop5h 35m
Southwest
Mon 3/165:20 am
MAF
- SAT
1 stop3h 20m
Southwest
Deal found 2/9![Southwest logo]()
$337
This Southwest deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/135:35 am
SAT
- MAF
1 stop4h 30m
Southwest
Tue 3/177:55 am
MAF
- SAT
2 stops5h 45m
Southwest
Deal found 2/9![Southwest logo]()
$352
This Southwest deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/135:35 am
SAT
- MAF
1 stop4h 30m
Southwest
Sat 3/214:20 pm
MAF
- SAT
2 stops7h 35m
Southwest
Deal found 2/8![Southwest logo]()
$361
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/271:55 pm
SAT
- MAF
1 stop4h 15m
Southwest
Fri 4/37:25 am
MAF
- SAT
2 stops7h 00m
Southwest
Deal found 2/10![Southwest logo]()
$380
Last-minute flights from San Antonio to OdessaDiscover last-minute flight deals from San Antonio to Odessa. Data last updated February 10, 2026 and is based on user searches.
Discover last-minute flight deals from San Antonio to Odessa. Data last updated February 10, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/95:50 pm
SAT
- MAF
1 stop4h 00m
United Airlines
Mon 3/165:25 pm
MAF
- SAT
1 stop5h 32m
United Airlines
Deal found 2/9![United Airlines logo]()
$337
This Southwest deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/95:20 pm
SAT
- MAF
2 stops7h 00m
Southwest
Mon 3/165:20 am
MAF
- SAT
1 stop3h 20m
Southwest
Deal found 2/9![Southwest logo]()
$342
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/105:00 am
SAT
- MAF
1 stop3h 48m
American Airlines
Tue 3/249:18 am
MAF
- SAT
1 stop13h 36m
American Airlines
Deal found 2/8![American Airlines logo]()
$304
This Southwest deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1012:50 pm
SAT
- MAF
1 stop5h 35m
Southwest
Tue 3/2411:00 am
MAF
- SAT
2 stops4h 40m
Southwest
Deal found 2/8![Southwest logo]()
$324
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/135:00 am
SAT
- MAF
1 stop3h 48m
American Airlines
Tue 3/175:00 am
MAF
- SAT
1 stop9h 25m
American Airlines
Deal found 2/9![American Airlines logo]()
$299
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/135:00 am
SAT
- MAF
1 stop3h 48m
American Airlines
Sat 3/212:30 pm
MAF
- SAT
1 stop8h 37m
American Airlines
Deal found 2/8![American Airlines logo]()
$311
This Southwest deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/135:35 am
SAT
- MAF
1 stop4h 30m
Southwest
Tue 3/177:55 am
MAF
- SAT
2 stops5h 45m
Southwest
Deal found 2/9![Southwest logo]()
$352
This Southwest deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/135:35 am
SAT
- MAF
1 stop4h 30m
Southwest
Sat 3/214:20 pm
MAF
- SAT
2 stops7h 35m
Southwest
Deal found 2/8![Southwest logo]()
$361
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/277:45 pm
SAT
- MAF
1 stop3h 10m
Southwest
Fri 4/310:45 am
MAF
- SAT
1 stop3h 40m
Southwest
Deal found 2/10![Southwest logo]()
$375
One-way flights from San Antonio to OdessaSearch for one-way flight options from San Antonio to Odessa. Find affordable one-way fares based on user searches. Data last updated February 10, 2026.
Search for one-way flight options from San Antonio to Odessa. Find affordable one-way fares based on user searches. Data last updated February 10, 2026.
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2110:23 am
SAT
- MAF
1 stop7h 27m
American Airlines
Deal found 2/8![American Airlines logo]()
$129
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/166:40 pm
SAT
- MAF
1 stop5h 40m
Southwest
Deal found 2/10![Southwest logo]()
$169
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/228:08 pm
SAT
- MAF
1 stop4h 01m
American Airlines
Deal found 2/8![American Airlines logo]()
$188
This Southwest deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/211:20 pm
SAT
- MAF
2 stops8h 55m
Southwest
Deal found 2/8![Southwest logo]()
$203
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/245:58 pm
SAT
- MAF
1 stop3h 46m
United Airlines
Deal found 2/9![United Airlines logo]()
$250
This Southwest deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2410:10 am
SAT
- MAF
2 stops7h 20m
Southwest
Deal found 2/9![Southwest logo]()
$255
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/167:20 pm
SAT
- MAF
1 stop3h 55m
United Airlines
Deal found 2/8![United Airlines logo]()
$305
This Southwest deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/166:00 pm
SAT
- MAF
2 stops5h 05m
Southwest
Deal found 2/8![Southwest logo]()
$310
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/165:00 am
SAT
- MAF
1 stop3h 48m
American Airlines
Deal found 2/10![American Airlines logo]()
$371
Find flight deals from San Antonio to Odessa
Keep the following information in mind while searching for San Antonio to Odessa flight deals. Data was last updated February 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $299 (American Airlines) |
One-way from | $129 (American Airlines) |
Popular in | January |
Cheapest in | June |
Average price | $626 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Antonio to Odessa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 10, 2026.
Use the filters below to find and compare flights from San Antonio to Odessa that are best for you.
Fly from
San Antonio
Fly to
Odessa
Route
Depart
Return
Price
San AntonioMidland
SAT - MAF
SATMAF
San Antonio
Fri 3/13
5:00 am-8:48 am
1 stop3h 48m
Midland Intl
Tue 3/17
5:00 am-2:25 pm
1 stop9h 25m
$299
San AntonioMidland
SAT - MAF
SATMAF
San Antonio
Tue 3/10
5:00 am-8:48 am
1 stop3h 48m
Midland Intl
Tue 3/24
9:18 am-10:54 pm
1 stop13h 36m
$304
San AntonioMidland
SAT - MAF
SATMAF
San Antonio
Tue 3/10
12:50 pm-6:25 pm
1 stop5h 35m
Midland Intl
Tue 3/24
11:00 am-3:40 pm
2 stops4h 40m
$324
San AntonioMidland
SAT - MAF
SATMAF
San Antonio
Mon 3/9
5:50 pm-9:50 pm
1 stop4h 00m
Midland Intl
Mon 3/16
5:25 pm-10:57 pm
1 stop5h 32m
$337
San AntonioMidland
SAT - MAF
SATMAF
San Antonio
Mon 3/9
5:20 pm-10:55 pm
1 stop5h 35m
Midland Intl
Mon 3/16
5:20 am-8:40 am
1 stop3h 20m
$337
San AntonioMidland
SAT - MAF
SATMAF
San Antonio
Fri 3/13
5:35 am-10:05 am
1 stop4h 30m
Midland Intl
Tue 3/17
7:55 am-1:40 pm
2 stops5h 45m
$352
San AntonioMidland
SAT - MAF
SATMAF
San Antonio
Fri 3/13
5:35 am-10:05 am
1 stop4h 30m
Midland Intl
Sat 3/21
4:20 pm-11:55 pm
2 stops7h 35m
$361
San AntonioMidland
SAT - MAF
SATMAF
San Antonio
Fri 3/27
1:55 pm-6:10 pm
1 stop4h 15m
Midland Intl
Fri 4/3
7:25 am-2:25 pm
2 stops7h 00m
$380
San AntonioMidland
SAT - MAF
SATMAF
San Antonio
Sat 3/21
10:23 am-5:50 pm
1 stop7h 27m
$129
San AntonioMidland
SAT - MAF
SATMAF
San Antonio
Mon 3/16
6:40 pm-12:20 am
1 stop5h 40m
$169
Showing 1-10 of 19 results
Best time to book a flight from San Antonio to Odessa
Have a flexible travel schedule? Discover the best time to fly to Odessa from San Antonio with our price prediction graph.
SAT-MAF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Antonio to Odessa
SAT-OD3
SAT-MAF
What is the cheapest month to book a flight from San Antonio to Odessa?
Currently, June is the cheapest month in which you can book a flight from San Antonio to Odessa (average of $77). Flying from San Antonio to Odessa in December is currently the most expensive (average of $254). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Odessa
Get insights into the airlines that provide service to Odessa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Odessa. Reviews last updated February 10, 2026.
See what other customers who have flown with American Airlines from San Antonio to Odessa have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.9
Boarding
7.5
Overall
7.2
Crew
8.0
Comfort
7.2
Food
6.4
Reviews
1 / 20
8.0
ExcellentMonica,Nov 2025
JAC - DFW
Entertainment
6.9
Boarding
7.5
Overall
7.2
Crew
8.0
Comfort
7.2
Food
6.4
Reviews
1 / 20
8.0
ExcellentMonica,Nov 2025
JAC - DFW
Related info for your journey
Find useful and relevant information for your journey from San Antonio to Odessa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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San Antonio and Odessa flights
Browse other San Antonio and Odessa flight options. Last updated on February 10, 2026.
Other flights from San Antonio
Browse through other flights departing from San Antonio. Flights are based on user searches made on Cheapflights and were last updated on February 10, 2026.
Popular flight searches
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San Antonio to Odessa flights
Consider these flights traveling from San Antonio to Odessa.
Top airline flying from San Antonio to Odessa
Discover the top airline that operate flights from San Antonio to Odessa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$218 | Average$527 | FlexibilityNo cancel fee | On-time71% |