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Odessa

$99+ Cheap flights from Missouri to Odessa, TX

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/30. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MAF
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Cheap flight deals from Missouri to Odessa

Keep the following information in mind while searching for Missouri to Odessa flight deals. Data was last updated July 31, 2025.

Round-trip from

$253
(American Airlines)

One-way from

$99
(American Airlines)
From Missouri to Odessa
Search Deals
One-way flight from Missouri to Odessa
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Find flight deals from Missouri to Odessa

Cheapest flights from Missouri to Odessa
Explore the most affordable flight options available from Missouri to Odessa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/197:01 amSTL - MAF
1 stop7h 01mAmerican Airlines
Sat 8/306:33 pmMAF - STL
1 stop4h 41mAmerican Airlines
Deal found 7/30$253
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/149:17 amSTL - MAF
2 stops7h 20mDelta
Mon 8/185:30 amMAF - STL
2 stops12h 24mDelta
Deal found 7/30$319
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/148:00 amSTL - MAF
2 stops8h 13mUnited Airlines
Mon 8/185:18 pmMAF - STL
1 stop6h 41mUnited Airlines
Deal found 7/30$351
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/85:15 amSTL - MAF
1 stop4h 40mSouthwest
Wed 8/137:35 amMAF - STL
2 stops6h 55mSouthwest
Deal found 7/31$434

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Odessa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Missouri to Odessa that are best for you.

Fly from

Missouri

Fly to

Odessa

Route

Depart

Return

Price

St. LouisMidland

STL - MAF

STLMAF

Lambert-St Louis

Tue 8/19

7:01 am-2:02 pm

1 stop7h 01m

Midland Intl

Sat 8/30

6:33 pm-11:14 pm

1 stop4h 41m

$253

St. LouisMidland

STL - MAF

STLMAF

Lambert-St Louis

Thu 8/14

9:17 am-4:37 pm

2 stops7h 20m

Midland Intl

Mon 8/18

5:30 am-5:54 pm

2 stops12h 24m

$319

St. LouisMidland

STL - MAF

STLMAF

Lambert-St Louis

Thu 8/14

8:00 am-4:13 pm

2 stops8h 13m

Midland Intl

Mon 8/18

5:18 pm-11:59 pm

1 stop6h 41m

$351

St. LouisMidland

STL - MAF

STLMAF

Lambert-St Louis

Sat 8/30

5:15 am-9:39 am

1 stop4h 24m

$99

St. LouisMidland

STL - MAF

STLMAF

Lambert-St Louis

Sat 8/30

6:00 am-5:08 pm

2 stops11h 08m

$104

St. LouisMidland

STL - MAF

STLMAF

Lambert-St Louis

Sun 8/10

4:10 pm-11:55 pm

2 stops7h 45m

$275

St. LouisMidland

STL - MAF

STLMAF

Lambert-St Louis

Sat 8/16

5:30 pm-8:50 am

3 stops15h 20m

$378

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/31

Best time to book a flight from Missouri to Odessa

Have a flexible travel schedule? Discover the best time to fly to Odessa from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Odessa

What is the cheapest time of day to fly from MO to OD3?

Find hourly flight availability from Missouri to Odessa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Odessa as you normally would.

Reviews of airlines servicing Odessa

Get insights into the airlines that provide service to Odessa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Odessa. Reviews last updated July 31, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Missouri to Odessa by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,246 reviews

Food

7.0

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Southwest
8.0
Very good
4,246 reviews
Southwest
8.0
Very good
4,246 reviews

Food

7.0

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Delta
8.0
Very good
7,981 reviews
Southwest
8.0
Very good
4,246 reviews

Food

7.0

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
United Airlines
7.4
Good
8,900 reviews
Southwest
8.0
Very good
4,246 reviews

Food

7.0

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,246 reviews

Food

7.0

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Odessa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Missouri to Odessa one-way?

    $99 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on Delta and Southwest, with prices starting from $104 and $275, respectively.

  • Can I find deals for flights from Missouri to Odessa that include hotel bookings?

    Yes. In addition to deals on Missouri to Odessa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Odessa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Odessa.

  • Can I find deals for business class flights from Missouri to Odessa?

    Yes. Cheapflights offers flight deals from Missouri to Odessa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Odessa?

    Currently, April is the cheapest month in which you can book a flight from Missouri to Odessa (average of $336). Flying from Missouri to Odessa in March is currently the most expensive (average of $389). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Odessa

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Top 2 airlines flying from Missouri to Odessa

Discover the top 2 airlines that operate flights from Missouri to Odessa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$196Average$382FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$290Average$367FlexibilityNo cancel feeOn-time63%

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