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$234+ Cheap flights from Santa Fe (SAF) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/2. Fares are subject to change and may not be available on all flights or dates of travel.
SAF — STL
Aug 4 — Aug 111
Mon 8/4
Mon 8/11
1 adult, Economy
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Cheap flight deals from Santa Fe to Missouri

Keep the following information in mind while searching for Santa Fe to Missouri flight deals. Data was last updated July 30, 2025.

Round-trip from

$254
(American Airlines)

One-way from

$234
(American Airlines)

Popular in

September

Cheapest in

May

Average price

$487
From Santa Fe to Missouri
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One-way flight from Santa Fe to Missouri
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Highest demand for flights based on searches. 4% potential increase in price ($17 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($19 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Santa Fe to Missouri

Cheapest flights from Santa Fe to Missouri
Explore the most affordable flight options available from Santa Fe to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.

This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1411:42 amSAF - STL
1 stop6h 47mAmerican Airlines
Mon 8/185:15 amSTL - SAF
1 stop6h 52mAmerican Airlines
Deal found 7/30$254
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/295:59 pmSAF - STL
1 stop5h 00mUnited Airlines
Tue 8/55:15 amSTL - SAF
1 stop5h 07mUnited Airlines
Deal found 7/29$389

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Fe to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
Use the filters below to find and compare flights from Santa Fe to Missouri that are best for you.

Fly from

Santa Fe

Fly to

Missouri

Route

Depart

Return

Price

Santa FeSt. Louis

SAF - STL

SAFSTL

Santa Fe

Thu 8/14

11:42 am-7:29 pm

1 stop6h 47m

Lambert-St Louis

Mon 8/18

5:15 am-11:07 am

1 stop6h 52m

$254

Santa FeSt. Louis

SAF - STL

SAFSTL

Santa Fe

Thu 8/14

5:59 pm-11:59 pm

1 stop5h 00m

Lambert-St Louis

Mon 8/18

5:47 pm-12:40 pm

3 stops19h 53m

$533

Santa FeSt. Louis

SAF - STL

SAFSTL

Santa Fe

Tue 9/2

3:37 pm-12:16 am

1 stop7h 39m

$234

Santa FeSt. Louis

SAF - STL

SAFSTL

Santa Fe

Tue 9/2

7:00 am-3:44 pm

2 stops7h 44m

$279

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Best time to book a flight from Santa Fe to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Santa Fe with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Fe to Missouri

What is the cheapest month to book a flight from Santa Fe to Missouri?

Currently, August is the cheapest month in which you can book a flight from Santa Fe to Missouri (average of $311). Flying from Santa Fe to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated July 30, 2025.
Get a feel of what it's like to fly with United Airlines and American Airlines from Santa Fe to Missouri by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,896 reviews

Entertainment

7.1

Food

6.6

Overall

7.4

Crew

8.1

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
United Airlines
7.4
Good
8,896 reviews
United Airlines
7.4
Good
8,896 reviews

Entertainment

7.1

Food

6.6

Overall

7.4

Crew

8.1

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,896 reviews

Entertainment

7.1

Food

6.6

Overall

7.4

Crew

8.1

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Related info for your journey

Find useful and relevant information for your journey from Santa Fe to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Santa Fe to Missouri?

    Most people fly from Santa Fe (SAF) if they book a flight from Santa Fe to Missouri. Santa Fe is conveniently located just 9.8 mi from Santa Fe’s city center.

  • Can I find deals for flights from Santa Fe to Missouri that include hotel bookings?

    Yes. In addition to deals on Santa Fe to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Fe to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Fe to Missouri.

  • Can I find deals for business class flights from Santa Fe to Missouri?

    Yes. Cheapflights offers flight deals from Santa Fe to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Fe to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Santa Fe to Missouri (average of $311). Flying from Santa Fe to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Santa Fe to Missouri

Discover the top 2 airlines that operate flights from Santa Fe to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$194Average$377FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$243Average$441FlexibilityNo cancel feeOn-time69%

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