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$244+ Cheap flights from Santa Fe (SAF) to Missouri

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/10. Fares are subject to change and may not be available on all flights or dates of travel.
SAF — STL
Oct 14 — Oct 211
Tue 10/14
Tue 10/21
1 adult, Economy
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Cheap flight deals from Santa Fe to Missouri

Keep the following information in mind while searching for Santa Fe to Missouri flight deals. Data was last updated September 14, 2025.

Round-trip from

$244
(United Airlines)

Popular in

September

Cheapest in

May

Average price

$605
From Santa Fe to Missouri
Search Deals
Highest demand for flights based on searches. 27% potential increase in price ($157 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($21 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Santa Fe to Missouri

Cheapest flights from Santa Fe to Missouri
Explore the most affordable flight options available from Santa Fe to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2025.

This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/105:59 pmSAF - STL
1 stop4h 59mUnited Airlines
Sun 10/125:15 amSTL - SAF
1 stop5h 09mUnited Airlines
Deal found 9/14$244

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Fe to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 14, 2025.
Use the filters below to find and compare flights from Santa Fe to Missouri that are best for you.

Fly from

Santa Fe

Fly to

Missouri

Route

Depart

Return

Price

Santa FeSt. Louis

SAF - STL

SAFSTL

Santa Fe

Sat 2/28

10:45 am-4:34 pm

1 stop4h 49m

Lambert-St Louis

Tue 3/3

2:45 pm-8:50 pm

1 stop7h 05m

$344

Santa FeSt. Louis

SAF - STL

SAFSTL

Santa Fe

Sat 2/28

7:22 pm-9:27 am

2 stops13h 05m

Lambert-St Louis

Tue 3/3

5:27 am-9:26 am

1 stop4h 59m

$376

Santa FeSt. Louis

SAF - STL

SAFSTL

Santa Fe

Fri 10/10

5:59 pm-2:27 pm

2 stops19h 28m

Lambert-St Louis

Sun 10/12

5:15 am-9:24 am

1 stop5h 09m

$479

Santa FeSt. Louis

SAF - STL

SAFSTL

Santa Fe

Mon 9/22

5:18 pm-10:50 pm

1 stop4h 32m

$359

Santa FeSt. Louis

SAF - STL

SAFSTL

Santa Fe

Fri 9/19

10:03 am-6:22 pm

1 stop7h 19m

$398

Santa FeSt. Louis

SAF - STL

SAFSTL

Santa Fe

Fri 9/19

10:45 am-11:44 pm

2 stops11h 59m

$408

Santa FeSt. Louis

SAF - STL

SAFSTL

Santa Fe

Sun 9/21

7:00 am-12:43 pm

1 stop4h 43m

$435

Santa FeSt. Louis

SAF - STL

SAFSTL

Santa Fe

Mon 9/22

7:00 am-6:23 pm

2 stops10h 23m

$445

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Best time to book a flight from Santa Fe to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Santa Fe with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Fe to Missouri

What is the cheapest month to book a flight from Santa Fe to Missouri?

Currently, August is the cheapest month in which you can book a flight from Santa Fe to Missouri (average of $311). Flying from Santa Fe to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated September 14, 2025.
Get a feel of what it's like to fly with United Airlines and American Airlines from Santa Fe to Missouri by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,931 reviews

Food

6.6

Overall

7.4

Comfort

7.3

Boarding

7.7

Entertainment

7.1

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
United Airlines
7.4
Good
8,931 reviews
United Airlines
7.4
Good
8,931 reviews

Food

6.6

Overall

7.4

Comfort

7.3

Boarding

7.7

Entertainment

7.1

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,931 reviews

Food

6.6

Overall

7.4

Comfort

7.3

Boarding

7.7

Entertainment

7.1

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Related info for your journey

Find useful and relevant information for your journey from Santa Fe to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Santa Fe to Missouri?

    Most people fly from Santa Fe (SAF) if they book a flight from Santa Fe to Missouri. Santa Fe is conveniently located just 9.8 mi from Santa Fe’s city center.

  • How long is the flight from Santa Fe to Missouri?

    A quick flight from Santa Fe to Missouri can take about 4h 49m. United Airlines provides one of the quickest options available for as low as $344. The distance between Santa Fe and Missouri is about 890 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Santa Fe to Missouri that include hotel bookings?

    Yes. In addition to deals on Santa Fe to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Fe to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Fe to Missouri.

  • Can I find deals for business class flights from Santa Fe to Missouri?

    Yes. Cheapflights offers flight deals from Santa Fe to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Fe to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Santa Fe to Missouri (average of $311). Flying from Santa Fe to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Santa Fe to Missouri

Discover the top 2 airlines that operate flights from Santa Fe to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$194Average$376FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$254Average$369FlexibilityNo cancel feeOn-time69%

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