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$53+ Cheap flights from Portland (PDX) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/10. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — STL
Feb 7 — Feb 141
Sat 2/7
Sat 2/14
1 adult, Economy
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Cheap flight deals from Portland to Missouri

Keep the following information in mind while searching for Portland to Missouri flight deals. Data was last updated January 8, 2026.

Most accurate provider

CheapOair
3 stars

Most trusted provider

CheapOair
3 stars

Round-trip from

$105
(Alaska Airlines)

One-way from

$53
(Alaska Airlines)

Popular in

March

Cheapest in

November

Average price

$330

Good round-trip deal

$252 or less

Good one-way deal

$114 or less
Provider with most accurate pricing for Portland-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Portland-Lambert-St Louis flights.
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From Portland to Missouri
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One-way flight from Portland to Missouri
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($36 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Price to beat on a round-trip flight from Portland to Missouri.
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Price to beat on a one-way flight from Portland to Missouri.
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Find flight deals from Portland to Missouri

Cheapest flights from Portland to Missouri
Explore the most affordable flight options available from Portland to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 8, 2026.

This Alaska Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2210:45 amPDX - MCI
Nonstop3h 32mAlaska Airlines
Tue 4/285:11 pmMCI - PDX
Nonstop3h 52mAlaska Airlines
Deal found 1/7$105
This Alaska Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/279:39 amPDX - MCI
Nonstop3h 26mAlaska Airlines
Thu 1/293:59 pmMCI - PDX
Nonstop3h 58mAlaska Airlines
Deal found 1/6$112
This Alaska Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/1310:53 amPDX - MCI
Nonstop3h 29mAlaska Airlines
Fri 3/205:41 pmMCI - PDX
Nonstop3h 51mAlaska Airlines
Deal found 1/7$119
This Alaska Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/610:53 amPDX - MCI
Nonstop3h 29mAlaska Airlines
Tue 3/105:16 pmMCI - PDX
Nonstop4h 04mAlaska Airlines
Deal found 1/7$126
This Travelocity deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2810:45 amPDX - MCI
Nonstop3h 32mAlaska Airlines
Sat 5/27:00 amMCI - PDX
1 stop5h 56mAlaska Airlines
Deal found 1/7$129
This Alaska Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/2310:53 amPDX - MCI
Nonstop3h 29mAlaska Airlines
Fri 2/275:16 pmMCI - PDX
Nonstop4h 04mAlaska Airlines
Deal found 1/7$133
This Southwest deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/104:55 pmPDX - MCI
1 stop5h 55mSouthwest
Mon 4/133:10 pmMCI - PDX
1 stop8h 30mSouthwest
Deal found 1/8$141
This Kiwi.com deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/812:04 pmPDX - STL
1 stop19h 45mFrontier
Wed 3/118:12 pmSTL - PDX
1 stop16h 57mFrontier
Deal found 1/7$141
This Alaska Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/19:39 amPDX - MCI
Nonstop3h 26mAlaska Airlines
Fri 2/62:45 pmMCI - PDX
1 stop8h 02mAlaska Airlines
Deal found 1/7$143
This Kiwi.com deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/912:52 pmPDX - STL
1 stop28h 19mFrontier
Wed 3/118:12 pmSTL - PDX
1 stop16h 57mFrontier
Deal found 1/7$151
This Kiwi.com deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/612:04 pmPDX - STL
1 stop19h 45mFrontier
Wed 3/118:12 pmSTL - PDX
1 stop16h 57mFrontier
Deal found 1/7$156
This Kiwi.com deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/612:04 pmPDX - STL
1 stop19h 45mFrontier
Sun 3/89:22 pmSTL - PDX
1 stop13h 36mFrontier
Deal found 1/7$166

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
Use the filters below to find and compare flights from Portland to Missouri that are best for you.

Fly from

Portland

Fly to

Missouri

Route

Depart

Return

Price

PortlandKansas City

PDX - MCI

PDXMCI

Portland

Tue 1/27

9:39 am-3:05 pm

Nonstop3h 26m

Kansas City

Thu 1/29

3:59 pm-5:57 pm

Nonstop3h 58m

$112

PortlandKansas City

PDX - MCI

PDXMCI

Portland

Fri 3/13

10:53 am-4:22 pm

Nonstop3h 29m

Kansas City

Fri 3/20

5:41 pm-7:32 pm

Nonstop3h 51m

$119

PortlandKansas City

PDX - MCI

PDXMCI

Portland

Mon 2/23

10:53 am-4:22 pm

Nonstop3h 29m

Kansas City

Thu 2/26

5:16 pm-7:20 pm

Nonstop4h 04m

$119

PortlandKansas City

PDX - MCI

PDXMCI

Portland

Mon 2/23

10:53 am-4:22 pm

Nonstop3h 29m

Kansas City

Fri 2/27

5:16 pm-7:20 pm

Nonstop4h 04m

$133

PortlandKansas City

PDX - MCI

PDXMCI

Portland

Sun 2/1

9:39 am-3:05 pm

Nonstop3h 26m

Kansas City

Fri 2/6

2:45 pm-8:47 pm

1 stop8h 02m

$143

PortlandKansas City

PDX - MCI

PDXMCI

Portland

Fri 3/6

8:30 am-9:29 pm

1 stop10h 59m

Kansas City

Tue 3/10

5:16 pm-7:20 pm

Nonstop4h 04m

$150

PortlandKansas City

PDX - MCI

PDXMCI

Portland

Mon 2/23

3:59 pm-11:50 pm

1 stop5h 51m

Kansas City

Fri 2/27

7:55 pm-11:53 pm

1 stop5h 58m

$157

PortlandSt. Louis

PDX - STL

PDXSTL

Portland

Wed 3/4

6:40 am-3:28 pm

1 stop6h 48m

Lambert-St Louis

Mon 3/9

4:13 pm-11:09 pm

1 stop8h 56m

$177

PortlandSt. Louis

PDX - STL

PDXSTL

Portland

Sat 2/28

1:32 pm-9:38 pm

1 stop6h 06m

Lambert-St Louis

Tue 3/10

12:28 pm-5:39 pm

1 stop7h 11m

$177

PortlandSt. Louis

PDX - STL

PDXSTL

Portland

Sat 1/31

10:15 pm-9:40 am

1 stop9h 25m

Lambert-St Louis

Wed 2/4

8:31 am-1:53 pm

1 stop7h 22m

$177

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/8

Showing 1-10 of 60 results
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Best time to book a flight from Portland to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Missouri

What is the cheapest month to book a flight from Portland to Missouri?

Currently, October is the cheapest month in which you can book a flight from Portland to Missouri (average of $133). Flying from Portland to Missouri in June is currently the most expensive (average of $236). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PDX to MO?

Find hourly flight availability from Portland to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 8, 2026.

When flying from Portland to Missouri, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost to fly round-trip from Portland to Missouri?

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated January 8, 2026.
Get a feel of what it's like to fly with Alaska Airlines, Southwest, and Delta from Portland to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
11,661 reviews

Boarding

8.1

Crew

8.5

Food

7.1

Entertainment

7.0

Comfort

7.8

Overall

8.0

Reviews

1 / 20
4.0
Okay

Anonymous,Dec 2025

SEA - MSY

I really got a lesson in upgrades. I let my seat get chosen . Both times a middle seat...on purpose ...even when we were not full. That's petty I sat behind the first class . They got more than 1 drink ...and a snack . .and the staff actually talked to them...behind a see thru shawl/sheet in the aisle....... You could see over the seats just fine and you could hear the voices just fine. But the sheet let You KNOW. Your not welcome here. For a moment I regretted not spending 300 dollars per seat so I could see a smile and eat a sandwhich and enjoy my seat . The married couple drank champain and laughed and flirted with each other. It looked so happy and care free MONEY really does buy happiness ..the hateful glares and sighs from my seat mates brought me back to reality I wasn't rich and I still had 2 hours left in this middle seat.
Alaska Airlines
8.0
Very good
11,661 reviews
Alaska Airlines
8.0
Very good
11,661 reviews

Boarding

8.1

Crew

8.5

Food

7.1

Entertainment

7.0

Comfort

7.8

Overall

8.0

Reviews

1 / 20
4.0
Okay

Anonymous,Dec 2025

SEA - MSY

I really got a lesson in upgrades. I let my seat get chosen . Both times a middle seat...on purpose ...even when we were not full. That's petty I sat behind the first class . They got more than 1 drink ...and a snack . .and the staff actually talked to them...behind a see thru shawl/sheet in the aisle....... You could see over the seats just fine and you could hear the voices just fine. But the sheet let You KNOW. Your not welcome here. For a moment I regretted not spending 300 dollars per seat so I could see a smile and eat a sandwhich and enjoy my seat . The married couple drank champain and laughed and flirted with each other. It looked so happy and care free MONEY really does buy happiness ..the hateful glares and sighs from my seat mates brought me back to reality I wasn't rich and I still had 2 hours left in this middle seat.
Southwest
8.0
Very good
4,250 reviews
Alaska Airlines
8.0
Very good
11,661 reviews

Boarding

8.1

Crew

8.5

Food

7.1

Entertainment

7.0

Comfort

7.8

Overall

8.0

Reviews

1 / 20
4.0
Okay

Anonymous,Dec 2025

SEA - MSY

I really got a lesson in upgrades. I let my seat get chosen . Both times a middle seat...on purpose ...even when we were not full. That's petty I sat behind the first class . They got more than 1 drink ...and a snack . .and the staff actually talked to them...behind a see thru shawl/sheet in the aisle....... You could see over the seats just fine and you could hear the voices just fine. But the sheet let You KNOW. Your not welcome here. For a moment I regretted not spending 300 dollars per seat so I could see a smile and eat a sandwhich and enjoy my seat . The married couple drank champain and laughed and flirted with each other. It looked so happy and care free MONEY really does buy happiness ..the hateful glares and sighs from my seat mates brought me back to reality I wasn't rich and I still had 2 hours left in this middle seat.
Delta
7.9
Good
8,025 reviews
Alaska Airlines
8.0
Very good
11,661 reviews

Boarding

8.1

Crew

8.5

Food

7.1

Entertainment

7.0

Comfort

7.8

Overall

8.0

Reviews

1 / 20
4.0
Okay

Anonymous,Dec 2025

SEA - MSY

I really got a lesson in upgrades. I let my seat get chosen . Both times a middle seat...on purpose ...even when we were not full. That's petty I sat behind the first class . They got more than 1 drink ...and a snack . .and the staff actually talked to them...behind a see thru shawl/sheet in the aisle....... You could see over the seats just fine and you could hear the voices just fine. But the sheet let You KNOW. Your not welcome here. For a moment I regretted not spending 300 dollars per seat so I could see a smile and eat a sandwhich and enjoy my seat . The married couple drank champain and laughed and flirted with each other. It looked so happy and care free MONEY really does buy happiness ..the hateful glares and sighs from my seat mates brought me back to reality I wasn't rich and I still had 2 hours left in this middle seat.
United Airlines
7.4
Good
9,139 reviews
Alaska Airlines
8.0
Very good
11,661 reviews

Boarding

8.1

Crew

8.5

Food

7.1

Entertainment

7.0

Comfort

7.8

Overall

8.0

Reviews

1 / 20
4.0
Okay

Anonymous,Dec 2025

SEA - MSY

I really got a lesson in upgrades. I let my seat get chosen . Both times a middle seat...on purpose ...even when we were not full. That's petty I sat behind the first class . They got more than 1 drink ...and a snack . .and the staff actually talked to them...behind a see thru shawl/sheet in the aisle....... You could see over the seats just fine and you could hear the voices just fine. But the sheet let You KNOW. Your not welcome here. For a moment I regretted not spending 300 dollars per seat so I could see a smile and eat a sandwhich and enjoy my seat . The married couple drank champain and laughed and flirted with each other. It looked so happy and care free MONEY really does buy happiness ..the hateful glares and sighs from my seat mates brought me back to reality I wasn't rich and I still had 2 hours left in this middle seat.
American Airlines
7.2
Good
11,095 reviews
Alaska Airlines
8.0
Very good
11,661 reviews

Boarding

8.1

Crew

8.5

Food

7.1

Entertainment

7.0

Comfort

7.8

Overall

8.0

Reviews

1 / 20
4.0
Okay

Anonymous,Dec 2025

SEA - MSY

I really got a lesson in upgrades. I let my seat get chosen . Both times a middle seat...on purpose ...even when we were not full. That's petty I sat behind the first class . They got more than 1 drink ...and a snack . .and the staff actually talked to them...behind a see thru shawl/sheet in the aisle....... You could see over the seats just fine and you could hear the voices just fine. But the sheet let You KNOW. Your not welcome here. For a moment I regretted not spending 300 dollars per seat so I could see a smile and eat a sandwhich and enjoy my seat . The married couple drank champain and laughed and flirted with each other. It looked so happy and care free MONEY really does buy happiness ..the hateful glares and sighs from my seat mates brought me back to reality I wasn't rich and I still had 2 hours left in this middle seat.

Related info for your journey

Find useful and relevant information for your journey from Portland to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Portland to Missouri?

    Most people fly from Portland (PDX) if they book a flight from Portland to Missouri. Portland is conveniently located just 6.0 mi from Portland’s city center.

  • How long is the flight from Portland to Missouri?

    Alaska Airlines, American Airlines, and Delta can get you from Portland to Missouri in just under 3h 26m. Your travel time can differ by up to 3h 22m. The distance between Portland and Missouri is about 1477 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Portland to Missouri?

    The most popular flight routes from Portland to Missouri are Portland - Lambert-St Louis, Portland - Kansas City and Portland - Springfield-Branson.

  • What are the cheapest flights from Portland to Missouri?

    The cheapest flight price from Portland to Missouri is $114. On average you can expect to pay $114. The most popular route, (Portland - Lambert-St Louis), can usually be booked for $177.

  • Can I find deals for flights from Portland to Missouri that include hotel bookings?

    Yes. In addition to deals on Portland to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Missouri.

  • Can I find deals for business class flights from Portland to Missouri?

    Yes. Cheapflights offers flight deals from Portland to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland to Missouri?

    Currently, October is the cheapest month in which you can book a flight from Portland to Missouri (average of $133). Flying from Portland to Missouri in June is currently the most expensive (average of $236). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Portland to Missouri

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Top 7 airlines flying from Portland to Missouri

Discover the top 7 airlines that operate flights from Portland to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$96Average$226FlexibilityNo cancel feeOn-time62%
DeltaCheapest$154Average$355FlexibilityNo cancel feeOn-timeN/A
Alaska AirlinesCheapest$185Average$437FlexibilityNo cancel feeOn-time75%
Hawaiian AirlinesCheapest$193Average$354FlexibilityNo cancel feeOn-time85%
SouthwestCheapest$226Average$395FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$226Average$409FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$226Average$404FlexibilityNo cancel feeOn-time69%

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