$65+ Cheap flights from Portland (PDX) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/26. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — STL
May 24 — May 312
Round-trip
2 travelers, Economy
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Find cheap flights from Portland to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Portland to MissouriExplore the most affordable flight options available from Portland to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2026.
Explore the most affordable flight options available from Portland to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2026.
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/185:05 pm
PDX
- STL
1 stop5h 31m
Delta
Tue 8/257:30 am
STL
- PDX
1 stop7h 01m
Delta
Deal found 4/20![Delta logo]()
$205
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2710:59 pm
PDX
- MCI
1 stop7h 36m
American Airlines
Wed 6/37:46 pm
MCI
- PDX
1 stop7h 04m
American Airlines
Deal found 4/20![American Airlines logo]()
$215
This CheapOair deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/118:46 pm
PDX
- STL
1 stop19h 20m
Frontier
Thu 5/1412:36 pm
STL
- PDX
1 stop10h 15m
Frontier
Deal found 4/19![Frontier logo]()
$216
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/231:35 pm
PDX
- STL
1 stop7h 46m
Delta
Tue 5/261:59 pm
STL
- PDX
1 stop10h 03m
Delta
Deal found 4/21![Delta logo]()
$224
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2311:43 pm
PDX
- MCI
1 stop8h 55m
American Airlines
Wed 5/275:16 pm
MCI
- PDX
1 stop8h 43m
American Airlines
Deal found 4/21![American Airlines logo]()
$236
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1811:30 pm
PDX
- STL
1 stop8h 05m
Southwest
Tue 8/255:35 am
STL
- PDX
2 stops11h 50m
Southwest
Deal found 4/20![Southwest logo]()
$237
This CheapOair deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/112:35 pm
PDX
- STL
1 stop28h 48m
Frontier
Sun 6/79:06 pm
STL
- PDX
1 stop15h 14m
Frontier
Deal found 4/19![Frontier logo]()
$241
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:35 am
PDX
- MCI
2 stops8h 25m
Southwest
Mon 8/314:55 pm
MCI
- PDX
1 stop6h 15m
Southwest
Deal found 4/20![Southwest logo]()
$242
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2310:59 pm
PDX
- STL
1 stop7h 33m
American Airlines
Sat 5/307:20 pm
STL
- PDX
1 stop7h 30m
American Airlines
Deal found 4/20![American Airlines logo]()
$243
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/311:43 pm
PDX
- STL
1 stop7h 08m
American Airlines
Fri 6/55:00 pm
STL
- PDX
1 stop8h 56m
American Airlines
Deal found 4/22![American Airlines logo]()
$244
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:45 am
PDX
- STL
1 stop5h 47m
Delta
Tue 5/261:59 pm
STL
- PDX
1 stop10h 03m
Delta
Deal found 4/22![Delta logo]()
$251
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2010:35 am
PDX
- MCI
1 stop8h 16m
United Airlines
Mon 8/247:10 pm
MCI
- PDX
1 stop5h 42m
United Airlines
Deal found 4/23![United Airlines logo]()
$252
Best flights from Portland to MissouriDiscover carefully curated flight deals from Portland to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 24, 2026.
Discover carefully curated flight deals from Portland to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 24, 2026.
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/213:10 pm
PDX
- STL
1 stop6h 11m
Delta
Wed 5/271:59 pm
STL
- PDX
1 stop10h 03m
Delta
Deal found 4/23![Delta logo]()
$257
This Alaska Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/2510:37 am
PDX
- STL
Nonstop4h 00m
Alaska Airlines
Wed 5/275:33 pm
STL
- PDX
Nonstop4h 17m
Alaska Airlines
Deal found 4/18![Alaska Airlines logo]()
$283
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/55:00 pm
PDX
- MCI
1 stop6h 30m
Southwest
Sun 6/712:35 pm
MCI
- PDX
Nonstop3h 35m
Southwest
Deal found 4/20![Southwest logo]()
$303
This United Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1910:35 am
PDX
- MCI
1 stop8h 16m
United Airlines
Sun 8/236:00 am
MCI
- PDX
1 stop5h 21m
United Airlines
Deal found 4/19![United Airlines logo]()
$322
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:40 am
PDX
- COU
1 stop8h 34m
American Airlines
Mon 6/16:32 pm
COU
- PDX
1 stop7h 20m
American Airlines
Deal found 4/21![American Airlines logo]()
$358
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:00 am
PDX
- STL
1 stop8h 46m
Delta
Wed 5/2011:25 am
STL
- PDX
1 stop7h 50m
Delta
Deal found 4/22![Delta logo]()
$271
This Alaska Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2410:37 am
PDX
- STL
Nonstop4h 00m
Alaska Airlines
Tue 5/265:33 pm
STL
- PDX
Nonstop4h 17m
Alaska Airlines
Deal found 4/18![Alaska Airlines logo]()
$309
This Southwest deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/265:00 pm
PDX
- MCI
1 stop6h 30m
Southwest
Mon 6/293:30 pm
MCI
- PDX
1 stop8h 40m
Southwest
Deal found 4/22![Southwest logo]()
$327
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/211:40 pm
PDX
- MCI
1 stop8h 49m
United Airlines
Sat 6/64:26 pm
MCI
- PDX
2 stops8h 22m
United Airlines
Deal found 4/22![United Airlines logo]()
$332
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:12 pm
PDX
- STL
1 stop8h 17m
Delta
Sun 5/316:21 am
STL
- PDX
1 stop6h 32m
Delta
Deal found 4/21![Delta logo]()
$315
This Southwest deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1611:30 pm
PDX
- MCI
1 stop7h 50m
Southwest
Thu 7/28:15 pm
MCI
- PDX
1 stop6h 15m
Southwest
Deal found 4/18![Southwest logo]()
$327
This Alaska Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/299:44 am
PDX
- STL
1 stop7h 01m
Alaska Airlines
Sat 5/305:33 pm
STL
- PDX
Nonstop4h 17m
Alaska Airlines
Deal found 4/22![Alaska Airlines logo]()
$342
This Delta deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/185:24 pm
PDX
- MCI
1 stop4h 54m
Delta
Wed 6/246:23 am
MCI
- PDX
1 stop6h 21m
Delta
Deal found 4/19![Delta logo]()
$327
This Southwest deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:00 am
PDX
- MCI
2 stops10h 05m
Southwest
Tue 6/26:55 pm
MCI
- PDX
1 stop6h 15m
Southwest
Deal found 4/19![Southwest logo]()
$357
This Alaska Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:00 am
PDX
- MCI
1 stop6h 57m
Alaska Airlines
Sat 6/65:52 pm
MCI
- PDX
Nonstop3h 52m
Alaska Airlines
Deal found 4/21![Alaska Airlines logo]()
$361
This United Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/167:45 pm
PDX
- STL
2 stops10h 54m
United Airlines
Sat 5/237:23 pm
STL
- PDX
1 stop7h 27m
United Airlines
Deal found 4/18![United Airlines logo]()
$402
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3011:43 pm
PDX
- SGF
1 stop8h 47m
American Airlines
Sun 6/76:43 pm
SGF
- PDX
1 stop8h 07m
American Airlines
Deal found 4/23![American Airlines logo]()
$445
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/251:25 pm
PDX
- MCI
1 stop8h 24m
Delta
Sat 6/277:00 am
MCI
- PDX
1 stop6h 43m
Delta
Deal found 4/22![Delta logo]()
$352
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/511:55 pm
PDX
- COU
1 stop9h 00m
United Airlines
Sat 5/93:10 pm
COU
- PDX
1 stop9h 25m
United Airlines
Deal found 4/20![United Airlines logo]()
$408
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/173:30 pm
PDX
- MCI
1 stop6h 55m
Southwest
Thu 5/218:20 pm
MCI
- PDX
1 stop6h 35m
Southwest
Deal found 4/20![Southwest logo]()
$382
This Southwest deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/299:20 pm
PDX
- MCI
1 stop10h 45m
Southwest
Sun 8/212:35 pm
MCI
- PDX
Nonstop3h 35m
Southwest
Deal found 4/19![Southwest logo]()
$383
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/111:47 pm
PDX
- COU
1 stop7h 59m
American Airlines
Sun 5/34:28 pm
COU
- PDX
1 stop9h 29m
American Airlines
Deal found 4/23![American Airlines logo]()
$518
This Alaska Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2810:37 am
PDX
- STL
Nonstop4h 00m
Alaska Airlines
Sun 5/315:33 pm
STL
- PDX
Nonstop4h 17m
Alaska Airlines
Deal found 4/19![Alaska Airlines logo]()
$431
This Southwest deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2911:30 pm
PDX
- STL
1 stop7h 40m
Southwest
Sun 8/24:45 pm
STL
- PDX
Nonstop4h 05m
Southwest
Deal found 4/22![Southwest logo]()
$383
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:00 am
PDX
- SGF
1 stop7h 08m
United Airlines
Sun 5/103:00 pm
SGF
- PDX
1 stop9h 59m
United Airlines
Deal found 4/21![United Airlines logo]()
$487
This Alaska Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3010:30 am
PDX
- SGF
1 stop8h 01m
Alaska Airlines
Wed 6/39:29 am
SGF
- PDX
2 stops11h 54m
Alaska Airlines
Deal found 4/19![Alaska Airlines logo]()
$471
This Southwest deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1211:55 pm
PDX
- STL
1 stop7h 35m
Southwest
Wed 5/205:30 am
STL
- PDX
2 stops10h 20m
Southwest
Deal found 4/22![Southwest logo]()
$393
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/202:38 pm
PDX
- JLN
1 stop20h 44m
United Airlines
Wed 5/271:57 pm
JLN
- PDX
1 stop5h 47m
United Airlines
Deal found 4/23![United Airlines logo]()
$494
This Southwest deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:30 am
PDX
- STL
2 stops9h 25m
Southwest
Tue 5/193:55 pm
STL
- PDX
1 stop8h 05m
Southwest
Deal found 4/18![Southwest logo]()
$402
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1511:55 pm
PDX
- SGF
1 stop8h 45m
United Airlines
Mon 5/184:50 pm
SGF
- PDX
1 stop8h 09m
United Airlines
Deal found 4/21![United Airlines logo]()
$513
Last-minute flights from Portland to MissouriDiscover last-minute flight deals from Portland to Missouri. Data last updated April 24, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Missouri. Data last updated April 24, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/2611:15 am
PDX
- STL
1 stop6h 06m
Frontier
Thu 4/309:55 pm
STL
- PDX
1 stop13h 04m
Frontier
Deal found 4/21![Frontier logo]()
$260
This CheapOair deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/118:46 pm
PDX
- STL
1 stop19h 20m
Frontier
Thu 5/1412:36 pm
STL
- PDX
1 stop10h 15m
Frontier
Deal found 4/19![Frontier logo]()
$216
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/131:35 pm
PDX
- MCI
1 stop8h 24m
Delta
Fri 5/157:26 am
MCI
- PDX
1 stop7h 10m
Delta
Deal found 4/21![Delta logo]()
$257
This CheapOair deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1512:35 pm
PDX
- STL
1 stop28h 48m
Frontier
Sat 5/236:30 pm
STL
- PDX
1 stop17h 50m
Frontier
Deal found 4/23![Frontier logo]()
$241
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:45 am
PDX
- STL
1 stop5h 47m
Delta
Tue 5/261:59 pm
STL
- PDX
1 stop10h 03m
Delta
Deal found 4/22![Delta logo]()
$251
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1911:55 pm
PDX
- MCI
1 stop7h 20m
Southwest
Fri 6/54:15 pm
MCI
- PDX
1 stop6h 45m
Southwest
Deal found 4/20![Southwest logo]()
$258
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/213:10 pm
PDX
- STL
1 stop6h 11m
Delta
Wed 5/277:59 pm
STL
- PDX
1 stop5h 45m
Delta
Deal found 4/21![Delta logo]()
$257
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/231:35 pm
PDX
- STL
1 stop7h 46m
Delta
Tue 5/261:59 pm
STL
- PDX
1 stop10h 03m
Delta
Deal found 4/21![Delta logo]()
$224
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2311:43 pm
PDX
- MCI
1 stop8h 55m
American Airlines
Wed 5/275:16 pm
MCI
- PDX
1 stop8h 43m
American Airlines
Deal found 4/21![American Airlines logo]()
$236
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2310:59 pm
PDX
- STL
1 stop7h 33m
American Airlines
Sat 5/307:20 pm
STL
- PDX
1 stop7h 30m
American Airlines
Deal found 4/20![American Airlines logo]()
$243
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2710:59 pm
PDX
- MCI
1 stop7h 36m
American Airlines
Wed 6/37:46 pm
MCI
- PDX
1 stop7h 04m
American Airlines
Deal found 4/20![American Airlines logo]()
$215
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/294:15 pm
PDX
- STL
1 stop5h 42m
United Airlines
Sat 5/306:00 am
STL
- PDX
1 stop7h 38m
United Airlines
Deal found 4/21![United Airlines logo]()
$258
One-way flights from Portland to MissouriSearch for one-way flight options from Portland to Missouri. Find affordable one-way fares based on user searches. Data last updated April 24, 2026.
Search for one-way flight options from Portland to Missouri. Find affordable one-way fares based on user searches. Data last updated April 24, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:46 pm
PDX
- MCI
1 stop18h 03m
Frontier
Deal found 4/23![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1812:35 pm
PDX
- MCI
1 stop23h 14m
Frontier
Deal found 4/21![Frontier logo]()
$67
This CheapOair deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/118:46 pm
PDX
- STL
1 stop19h 20m
Frontier
Deal found 4/19![Frontier logo]()
$92
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:05 pm
PDX
- STL
1 stop5h 25m
Delta
Deal found 4/20![Delta logo]()
$103
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/193:30 pm
PDX
- MCI
1 stop5h 40m
Delta
Deal found 4/21![Delta logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1812:35 pm
PDX
- STL
2 stops27h 31m
Frontier
Deal found 4/21![Frontier logo]()
$113
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1911:35 am
PDX
- MCI
2 stops8h 45m
Southwest
Deal found 4/21![Southwest logo]()
$114
This CheapOair deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/612:35 pm
PDX
- STL
1 stop28h 48m
Frontier
Deal found 4/21![Frontier logo]()
$117
This Trip.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:35 pm
PDX
- MCI
1 stop23h 14m
Frontier
Deal found 4/23![Frontier logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2312:35 pm
PDX
- STL
2 stops26h 58m
Frontier
Deal found 4/23![Frontier logo]()
$119
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/231:35 pm
PDX
- STL
1 stop7h 46m
Delta
Deal found 4/20![Delta logo]()
$122
This Frontier deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2111:15 am
PDX
- STL
1 stop6h 56m
Frontier
Deal found 4/19![Frontier logo]()
$125
Find flight deals from Portland to Missouri
Keep the following information in mind while searching for Portland to Missouri flight deals. Data was last updated April 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $205 (Delta) |
One-way from | $65 (Kiwi.com) |
Popular in | March |
Cheapest in | November |
Average price | $420 |
Good round-trip deal | $309 or less |
Good one-way deal | $164 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
Use the filters below to find and compare flights from Portland to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Thu 5/21
3:10 pm-11:21 pm
1 stop6h 11m
Lambert-St Louis
Wed 5/27
1:59 pm-10:02 pm
1 stop10h 03m
$257
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Tue 5/12
6:00 am-4:46 pm
1 stop8h 46m
Lambert-St Louis
Wed 5/20
11:25 am-5:15 pm
1 stop7h 50m
$271
Quickest round-trip
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Mon 5/25
10:37 am-4:37 pm
Nonstop4h 00m
Lambert-St Louis
Wed 5/27
5:33 pm-7:50 pm
Nonstop4h 17m
$283
PortlandKansas City
PDX - MCI
PDXMCI
Portland
Fri 6/5
5:00 pm-1:30 am
1 stop6h 30m
Kansas City
Sun 6/7
12:35 pm-2:10 pm
Nonstop3h 35m
$303
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Sun 5/24
10:37 am-4:37 pm
Nonstop4h 00m
Lambert-St Louis
Tue 5/26
5:33 pm-7:50 pm
Nonstop4h 17m
$309
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Thu 5/28
11:12 pm-9:29 am
1 stop8h 17m
Lambert-St Louis
Sun 5/31
6:21 am-10:53 am
1 stop6h 32m
$315
PortlandKansas City
PDX - MCI
PDXMCI
Portland
Wed 8/19
10:35 am-8:51 pm
1 stop8h 16m
Kansas City
Sun 8/23
6:00 am-9:21 am
1 stop5h 21m
$322
PortlandKansas City
PDX - MCI
PDXMCI
Portland
Fri 6/26
5:00 pm-1:30 am
1 stop6h 30m
Kansas City
Mon 6/29
3:30 pm-10:10 pm
1 stop8h 40m
$327
PortlandKansas City
PDX - MCI
PDXMCI
Portland
Tue 6/16
11:30 pm-9:20 am
1 stop7h 50m
Kansas City
Thu 7/2
8:15 pm-12:30 am
1 stop6h 15m
$327
PortlandKansas City
PDX - MCI
PDXMCI
Portland
Thu 6/18
5:24 pm-12:18 am
1 stop4h 54m
Kansas City
Wed 6/24
6:23 am-10:44 am
1 stop6h 21m
$327
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Portland to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Portland with our price prediction graph.
PDX-STL
PDX-MCI
PDX-SGF
PDX-JLN
PDX-COU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Missouri
PDX-USMO
PDX-STL
PDX-MCI
PDX-SGF
PDX-JLN
How far ahead should I book a flight from Portland to Missouri?
Booking 32 days in advance of your planned departure date is, on average, the best time to get cheap flights from Portland to Missouri. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Portland to Missouri?
Currently, July is the cheapest month in which you can book a flight from Portland to Missouri (average of $89). Flying from Portland to Missouri in January is currently the most expensive (average of $169). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PDX to MO?
Find hourly flight availability from Portland to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 24, 2026.
When flying from Portland to Missouri, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How much does it cost to fly round-trip from Portland to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated April 24, 2026.
Get a feel of what it's like to fly with Southwest,Alaska Airlines, andDelta from Portland to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Overall
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Overall
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Overall
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Overall
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Overall
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Boarding
8.1
Crew
8.6
Comfort
8.0
Overall
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Portland to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Portland to Missouri
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Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Portland to Missouri by cabin class
Find flights from Portland to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Portland and Missouri flights
Browse other Portland and Missouri flight options. Last updated on April 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Portland to Missouri flights
Consider these flights traveling from Portland to Missouri.
Top 7 airlines flying from Portland to Missouri
Discover the top 7 airlines that operate flights from Portland to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$75 | Average$241 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$108 | Average$341 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$180 | Average$396 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$186 | Average$307 | FlexibilityNo cancel fee | On-time85% | |
| Cheapest$196 | Average$398 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$216 | Average$400 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$228 | Average$412 | FlexibilityNo cancel fee | On-time71% |