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$351+ Cheap flights from Madrid, Spain (MAD) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/19. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — STL
oct. 16 — oct. 231
jue. 10/16
jue. 10/23
1 adult, Economy
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Cheap flight deals from Madrid to Missouri

Keep the following information in mind while searching for Madrid to Missouri flight deals. Data was last updated septiembre 16, 2025.

Round-trip from

$685
(Finnair)

One-way from

$351
(Kiwi.com)

Popular in

April

Cheapest in

March

Average price

$948
From Madrid Barajas to Missouri
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One-way flight from Madrid Barajas to Missouri
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Highest demand for flights based on searches. 3% potential increase in price ($34 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($37 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Madrid to Missouri

Cheapest flights from Madrid to Missouri
Explore the most affordable flight options available from Madrid to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 16, 2025.

This Expedia deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/221:45 pmMAD - STL
1 stop14h 21mIberia
lun. 9/297:59 pmSTL - MAD
1 stop10h 26mIberia
Deal found 9/14$708
This Finnair deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/2511:35 amMAD - STL
1 stop14h 35mMultiple Airlines
lun. 9/299:56 amSTL - MAD
1 stop14h 59mMultiple Airlines
Deal found 9/16$709
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/151:00 pmMAD - STL
1 stop12h 46mAmerican Airlines
mié. 10/222:15 pmSTL - MAD
1 stop16h 10mAmerican Airlines
Deal found 9/15$716
This Iberia deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/1011:35 amMAD - STL
1 stop15h 51mIberia
dom. 10/198:05 pmSTL - MAD
1 stop28h 50mIberia
Deal found 9/16$726
This Orbitz deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/156:55 amMAD - STL
2 stops20h 58mIberia
mié. 10/229:35 amSTL - MAD
1 stop13h 05mIberia
Deal found 9/15$733
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/1011:00 amMAD - STL
2 stops14h 43mAmerican Airlines
dom. 12/1410:47 amSTL - MAD
1 stop15h 08mAmerican Airlines
Deal found 9/15$739
This Iberia deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/312:55 amMAD - STL
1 stop28h 30mIberia
lun. 12/812:54 pmSTL - MAD
1 stop12h 01mIberia
Deal found 9/13$743
This Iberia deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/86:45 amMAD - STL
2 stops21h 06mIberia
mar. 12/167:00 amSTL - MAD
1 stop19h 25mIberia
Deal found 9/15$747
This Finnair deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/3112:40 pmMAD - STL
1 stop26h 13mMultiple Airlines
vie. 11/710:15 amSTL - MAD
1 stop12h 30mMultiple Airlines
Deal found 9/16$755
This Iberia deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/312:40 pmMAD - MCI
1 stop17h 21mIberia
mié. 12/101:44 pmMCI - MAD
1 stop12h 41mIberia
Deal found 9/13$765
This Expedia deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/221:45 pmMAD - MCI
1 stop15h 03mIberia
lun. 9/2910:46 amMCI - MAD
1 stop15h 19mIberia
Deal found 9/14$767
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/31:00 pmMAD - MCI
2 stops16h 54mAmerican Airlines
mié. 12/101:13 pmMCI - MAD
2 stops12h 37mAmerican Airlines
Deal found 9/13$778

Cheapflights Fare Finder

 
Customize your flight search to find flights from Madrid to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 16, 2025.
Use the filters below to find and compare flights from Madrid to Missouri that are best for you.

Fly from

Madrid

Fly to

Missouri

Route

Depart

Return

Price

MadridSt. Louis

MAD - STL

MADSTL

Madrid Barajas

vie. 2/6

10:00 am-9:48 pm

1 stop18h 48m

Lambert-St Louis

dom. 2/22

11:18 am-7:55 am

1 stop13h 37m

$685

MadridSt. Louis

MAD - STL

MADSTL

Madrid Barajas

sáb. 2/7

10:00 am-11:46 pm

1 stop20h 46m

Lambert-St Louis

dom. 2/22

11:18 am-7:55 am

1 stop13h 37m

$685

MadridSt. Louis

MAD - STL

MADSTL

Madrid Barajas

vie. 2/6

12:55 am-9:57 am

1 stop16h 02m

Lambert-St Louis

lun. 2/23

2:21 pm-10:20 am

1 stop12h 59m

$703

MadridSt. Louis

MAD - STL

MADSTL

Madrid Barajas

mié. 10/15

4:40 pm-11:54 pm

1 stop14h 14m

Lambert-St Louis

mié. 10/22

12:21 pm-9:05 am

1 stop13h 44m

$708

MadridSt. Louis

MAD - STL

MADSTL

Madrid Barajas

sáb. 2/7

7:40 am-8:23 pm

2 stops19h 43m

Lambert-St Louis

dom. 2/22

12:58 pm-7:55 am

1 stop11h 57m

$724

MadridSt. Louis

MAD - STL

MADSTL

Madrid Barajas

jue. 12/4

1:15 pm-8:21 pm

1 stop14h 06m

Lambert-St Louis

lun. 12/8

12:54 pm-7:55 am

1 stop12h 01m

$743

MadridSt. Louis

MAD - STL

MADSTL

Madrid Barajas

mié. 12/10

1:15 pm-8:51 pm

1 stop14h 36m

Lambert-St Louis

lun. 12/15

11:50 am-5:45 am

1 stop10h 55m

$743

MadridSt. Louis

MAD - STL

MADSTL

Madrid Barajas

lun. 12/8

1:15 pm-8:51 pm

1 stop14h 36m

Lambert-St Louis

mar. 12/16

11:50 am-5:45 am

1 stop10h 55m

$743

MadridKansas City

MAD - MCI

MADMCI

Madrid Barajas

vie. 12/5

12:55 am-9:55 am

1 stop16h 00m

Kansas City

jue. 12/11

1:44 pm-9:25 am

1 stop12h 41m

$780

MadridKansas City

MAD - MCI

MADMCI

Madrid Barajas

jue. 10/16

12:40 pm-10:32 pm

1 stop16h 52m

Kansas City

dom. 10/19

12:13 pm-9:05 am

1 stop13h 52m

$785

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 32 results
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Best time to book a flight from Madrid to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Madrid with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to Missouri

What is the cheapest month to book a flight from Madrid to Missouri?

Currently, August is the cheapest month in which you can book a flight from Madrid to Missouri (average of $311). Flying from Madrid to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Madrid to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Madrid to Missouri?

    Located just 8.5 mi from the city center, Madrid Barajas (MAD) is the airport most travelers will use when flying to Missouri from Madrid.

  • How long is the flight from Madrid to Missouri?

    For as low as $703, Iberia can have you in Missouri from Madrid in 16h 02m. The distance from Madrid to Missouri is about 4414 mi.

  • Can I find deals for flights from Madrid to Missouri that include hotel bookings?

    Yes. In addition to deals on Madrid to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Madrid to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to Missouri.

  • Can I find deals for business class flights from Madrid to Missouri?

    Yes. Cheapflights offers flight deals from Madrid to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Madrid to Missouri (average of $311). Flying from Madrid to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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