HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Madrid

$341+ Cheap flights from Missouri to Madrid, Spain (MAD)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/4. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MAD
May 17 — May 241
Sun 5/17
Sun 5/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Missouri to Madrid with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Missouri to Madrid

Cheapest flights from Missouri to Madrid
Explore the most affordable flight options available from Missouri to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2026.

This Gotogate deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/218:55 am
STL
-
MAD
1 stop17h 55m
Multiple Airlines
Fri 10/306:00 am
MAD
-
STL
1 stop14h 55m
Multiple Airlines
Deal found 4/13$705
This Cheapflightsfares deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:35 pm
STL
-
MAD
1 stop13h 00m
British Airways
Wed 10/2112:10 pm
MAD
-
STL
1 stop14h 20m
British Airways
Deal found 4/17$721
This oojo deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:35 pm
STL
-
MAD
1 stop13h 00m
British Airways
Fri 10/301:15 pm
MAD
-
STL
1 stop16h 26m
British Airways
Deal found 4/14$723
This Air Canada deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:55 pm
STL
-
MAD
2 stops28h 55m
Air Canada
Fri 10/21:30 pm
MAD
-
STL
2 stops31h 48m
Air Canada
Deal found 4/13$724
This United Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:40 am
STL
-
MAD
2 stops18h 25m
United Airlines
Wed 10/211:30 pm
MAD
-
STL
2 stops29h 50m
United Airlines
Deal found 4/13$725
This United Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/51:00 pm
STL
-
MAD
1 stop12h 05m
United Airlines
Wed 10/215:55 am
MAD
-
STL
1 stop14h 30m
United Airlines
Deal found 4/13$726
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/299:35 pm
STL
-
MAD
1 stop12h 55m
American Airlines
Fri 10/93:55 pm
MAD
-
STL
1 stop14h 46m
American Airlines
Deal found 4/15$728
This Gotogate deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:49 pm
STL
-
MAD
2 stops29h 01m
Air Canada
Wed 10/141:30 pm
MAD
-
STL
2 stops33h 08m
Air Canada
Deal found 4/14$729
This British Airways deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/299:35 pm
STL
-
MAD
1 stop12h 55m
British Airways
Tue 10/1312:10 pm
MAD
-
STL
1 stop14h 20m
British Airways
Deal found 4/13$730
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:01 am
STL
-
MAD
2 stops19h 04m
United Airlines
Fri 10/306:00 am
MAD
-
STL
1 stop14h 55m
United Airlines
Deal found 4/16$731
This Air Canada deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:55 pm
STL
-
MAD
2 stops28h 55m
Air Canada
Wed 9/3012:45 pm
MAD
-
STL
1 stop12h 56m
Air Canada
Deal found 4/13$732
This Cheapflightsfares deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/68:00 am
MCI
-
MAD
2 stops27h 40m
SWISS
Tue 10/2010:05 am
MAD
-
MCI
2 stops18h 29m
SWISS
Deal found 4/14$733

Find flight deals from Missouri to Madrid

Keep the following information in mind while searching for Missouri to Madrid flight deals. Data was last updated April 17, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$721
(Cheapflightsfares)

One-way from

$341
(oojo)

Popular in

June

Cheapest in

November

Average price

$725
Provider with most accurate pricing for Lambert-St Louis-Madrid Barajas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Madrid Barajas flights.
Search Deals
From Missouri to Madrid Barajas
Search Deals
One-way flight from Missouri to Madrid Barajas
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($229 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($36 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2026.
Use the filters below to find and compare flights from Missouri to Madrid that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Wed 10/7

1:30 pm-12:15 pm

1 stop15h 45m

Madrid Barajas

Wed 10/21

6:00 am-3:58 pm

2 stops16h 58m

$738

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Tue 9/29

1:30 pm-12:15 pm

1 stop15h 45m

Madrid Barajas

Fri 10/9

12:45 pm-11:39 pm

2 stops17h 54m

$740

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

Tue 10/13

6:00 am-8:05 am

2 stops19h 05m

Madrid Barajas

Tue 10/27

12:35 pm-3:10 pm

2 stops32h 35m

$744

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

Tue 10/6

6:00 am-9:00 am

2 stops20h 00m

Madrid Barajas

Tue 10/20

1:30 pm-10:33 am

2 stops28h 03m

$749

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

Sat 9/19

5:45 pm-8:05 am

1 stop31h 20m

Madrid Barajas

Tue 10/6

1:30 pm-10:07 pm

2 stops39h 37m

$750

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

Wed 10/7

10:10 am-6:20 am

1 stop13h 10m

Madrid Barajas

Thu 10/15

9:50 am-4:26 pm

1 stop13h 36m

$760

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

Wed 10/7

9:59 am-9:10 am

2 stops16h 11m

Madrid Barajas

Thu 10/15

9:50 am-4:26 pm

1 stop13h 36m

$764

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

Tue 10/6

1:13 pm-9:55 am

2 stops13h 42m

Madrid Barajas

Tue 10/20

12:45 pm-7:09 pm

1 stop13h 24m

$765

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

Wed 10/7

12:04 pm-9:55 am

2 stops14h 51m

Madrid Barajas

Thu 10/15

9:50 am-9:05 pm

1 stop18h 15m

$765

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

Tue 10/13

1:13 pm-9:55 am

2 stops13h 42m

Madrid Barajas

Tue 10/27

10:00 am-11:58 pm

2 stops19h 58m

$765

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/15

Showing 1-10 of 58 resultsSorted by cheapest first
1
2
3
...
6

Best time to book a flight from Missouri to Madrid

Have a flexible travel schedule? Discover the best time to fly to Madrid from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Madrid

What is the cheapest month to book a flight from Missouri to Madrid?

Currently, March is the cheapest month in which you can book a flight from Missouri to Madrid (average of $405). Flying from Missouri to Madrid in June is currently the most expensive (average of $761). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Missouri to Madrid?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Madrid. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Madrid from Missouri?

    Most people fly into Madrid Barajas (MAD) if they book a flight to Madrid from Missouri. Barajas is conveniently located just 8.5 mi from Madrid’s city center.

  • How long is the flight from Missouri to Madrid?

    For as low as $738, KLM can have you in Madrid from Missouri in 15h 45m. There are 4414 mi between Missouri and Madrid. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Missouri to Madrid one-way?

    The cheapest airlines for a one-way flight from Missouri to Madrid are United Airlines ($205), Delta ($288), and British Airways ($291).

  • What are the most popular routes from Missouri to Madrid?

    Most travelers choose Kansas City - Madrid Barajas, Lambert-St Louis - Madrid Barajas or Springfield-Branson - Madrid Barajas when deciding on the best route from Missouri to Madrid.

  • Can I find deals for flights from Missouri to Madrid that include hotel bookings?

    Yes. In addition to deals on Missouri to Madrid flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Madrid?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Madrid.

  • Can I find deals for business class flights from Missouri to Madrid?

    Yes. Cheapflights offers flight deals from Missouri to Madrid by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Madrid?

    Currently, March is the cheapest month in which you can book a flight from Missouri to Madrid (average of $405). Flying from Missouri to Madrid in June is currently the most expensive (average of $761). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Madrid?

Book flights to Madrid if you plan to visit one of these locations
Getafe

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 9 airlines flying from Missouri to Madrid

Discover the top 9 airlines that operate flights from Missouri to Madrid. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2026.
AirlineCheapestAverageFlexibilityOn-time
Virgin AtlanticCheapest$437Average$731FlexibilityNo cancel feeOn-time72%
Air FranceCheapest$457Average$754FlexibilityNo cancel feeOn-time77%
British AirwaysCheapest$478Average$719FlexibilityNo cancel feeOn-time70%
DeltaCheapest$487Average$809FlexibilityNo cancel feeOn-timeN/A
KLMCheapest$488Average$697FlexibilityNo cancel feeOn-time75%
IberiaCheapest$488Average$797FlexibilityNo cancel feeOn-time77%
American AirlinesCheapest$513Average$872FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$578Average$947FlexibilityNo cancel feeOn-time69%
Air CanadaCheapest$750Average$947FlexibilityNo cancel feeOn-time67%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.