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$333+ Cheap flights from Missouri to Madrid, Spain (MAD)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/1. Fares are subject to change and may not be available on all flights or dates of travel.
MCI — MAD
Aug 19 — Aug 261
Wed 8/19
Wed 8/26
1 adult, Economy
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Cheap flight deals from Missouri to Madrid

Cheapest flights from Missouri to Madrid
Explore the most affordable flight options available from Missouri to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 20, 2026.

This Gotogate deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/72:40 pm
STL
-
MAD
1 stop11h 55m
Multiple Airlines
Wed 10/215:55 am
MAD
-
STL
1 stop14h 30m
Multiple Airlines
Deal found 7/18$704
This Cheapflightsfares deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/63:14 pm
MCI
-
MAD
2 stops20h 26m
SWISS
Tue 10/2010:05 am
MAD
-
MCI
2 stops18h 59m
SWISS
Deal found 7/20$705
This Expedia deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/122:40 pm
STL
-
MAD
1 stop11h 10m
Air Canada
Tue 10/201:30 pm
MAD
-
STL
1 stop13h 30m
Air Canada
Deal found 7/19$705
This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/412:10 pm
STL
-
MAD
1 stop11h 40m
United Airlines
Wed 10/1412:45 pm
MAD
-
STL
2 stops30h 28m
United Airlines
Deal found 7/15$709
This United Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:10 am
MCI
-
MAD
1 stop19h 50m
United Airlines
Wed 10/1412:45 pm
MAD
-
MCI
2 stops42h 14m
United Airlines
Deal found 7/16$710
This United Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:30 am
STL
-
MAD
1 stop18h 30m
United Airlines
Wed 10/2112:45 pm
MAD
-
STL
2 stops33h 58m
United Airlines
Deal found 7/16$710
This Mytrip deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/37:36 am
MCI
-
MAD
2 stops17h 24m
Air Canada
Tue 11/171:25 pm
MAD
-
MCI
2 stops28h 01m
Air Canada
Deal found 7/15$713
This Travelocity deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am
STL
-
MAD
2 stops19h 00m
Air Canada
Wed 11/251:25 pm
MAD
-
STL
2 stops28h 16m
Air Canada
Deal found 7/16$713
This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1812:10 pm
STL
-
MAD
1 stop11h 40m
United Airlines
Wed 10/2112:45 pm
MAD
-
STL
2 stops30h 28m
United Airlines
Deal found 7/15$714
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/612:21 pm
MCI
-
MAD
1 stop12h 44m
United Airlines
Tue 10/201:30 pm
MAD
-
MCI
2 stops27h 56m
United Airlines
Deal found 7/20$715
This oojo deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:35 pm
STL
-
MAD
1 stop15h 30m
British Airways
Fri 10/301:00 pm
MAD
-
STL
1 stop14h 08m
British Airways
Deal found 7/20$717
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/263:14 pm
MCI
-
MAD
2 stops32h 36m
United Airlines
Tue 10/131:30 pm
MAD
-
MCI
2 stops34h 36m
United Airlines
Deal found 7/20$718

Find flight deals from Missouri to Madrid

Keep the following information in mind while searching for Missouri to Madrid flight deals. Data was last updated July 20, 2026.

Most accurate provider

Ovago
3 stars

Most trusted provider

Ovago
3 stars

Round-trip from

$704
(Gotogate)

One-way from

$333
(oojo)

Popular in

June

Cheapest in

February

Average price

$1,156
Provider with most accurate pricing for Lambert-St Louis-Madrid Barajas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Madrid Barajas flights.
Search Deals
From Missouri to Madrid Barajas
Search Deals
One-way flight from Missouri to Madrid Barajas
Search Deals
Highest demand for flights based on searches. 29% potential increase in price ($358 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($54 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 20, 2026.
Use the filters below to find and compare flights from Missouri to Madrid that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

Tue 10/6

6:00 am-8:05 am

2 stops19h 05m

Madrid Barajas

Tue 10/20

1:30 pm-10:26 am

2 stops27h 56m

$719
Quickest round-trip

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Sun 10/18

12:10 pm-6:50 am

1 stop11h 40m

Madrid Barajas

Wed 10/21

5:55 am-1:25 pm

1 stop14h 30m

$724

SpringfieldMadrid

SGF - MAD

SGFMAD

Springfield-Branson

Wed 9/23

7:03 am-9:05 am

1 stop19h 02m

Madrid Barajas

Wed 9/30

3:55 pm-9:08 am

1 stop24h 13m

$730

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

Wed 10/7

6:10 am-9:00 am

1 stop19h 50m

Madrid Barajas

Thu 10/15

10:50 am-11:59 pm

1 stop20h 09m

$730

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

Tue 10/13

12:00 pm-9:55 am

1 stop14h 55m

Madrid Barajas

Tue 10/27

7:00 am-6:33 pm

2 stops17h 33m

$731

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

Sat 9/26

6:39 pm-6:50 am

2 stops29h 11m

Madrid Barajas

Tue 10/13

5:55 am-10:35 pm

2 stops23h 40m

$733

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

Tue 11/3

8:40 am-7:45 am

1 stop16h 05m

Madrid Barajas

Tue 12/1

1:25 pm-2:30 pm

2 stops32h 05m

$740

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

Sat 10/17

6:39 pm-6:50 am

2 stops29h 11m

Madrid Barajas

Fri 10/23

1:30 pm-5:43 pm

2 stops35h 13m

$747

ColumbiaMadrid

COU - MAD

COUMAD

Columbia Regional

Fri 10/30

6:30 pm-7:00 am

2 stops30h 30m

Madrid Barajas

Wed 11/18

1:25 pm-10:44 am

2 stops28h 19m

$763

Kansas CityMadrid

MCI - MAD

MCIMAD

Kansas City

Thu 10/1

6:10 am-9:00 am

1 stop19h 50m

Madrid Barajas

Tue 10/20

1:30 pm-10:35 pm

2 stops40h 05m

$765

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/18

Showing 1-10 of 50 resultsSorted by cheapest first
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Best time to book a flight from Missouri to Madrid

Have a flexible travel schedule? Discover the best time to fly to Madrid from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Madrid

What is the cheapest month to book a flight from Missouri to Madrid?

Currently, February is the cheapest month in which you can book a flight from Missouri to Madrid (average of $628). Flying from Missouri to Madrid in June is currently the most expensive (average of $1,376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Missouri to Madrid?

How far ahead should I book a flight from Missouri to Madrid?

The price you pay for your flight from Missouri to Madrid may vary depending on when you book. For the best chance of a lower fare, look to book 88 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Madrid. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Madrid from Missouri?

    Most people fly into Madrid Barajas (MAD) if they book a flight to Madrid from Missouri. Barajas is conveniently located just 8.5 mi from Madrid’s city center.

  • How long is the flight from Missouri to Madrid?

    For as low as $731, United Airlines can have you in Madrid from Missouri in 14h 55m. There are 4589 mi between Missouri and Madrid. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Missouri to Madrid one-way?

    The cheapest airlines for a one-way flight from Missouri to Madrid are United Airlines ($205), Delta ($288), and British Airways ($291).

  • What are the most popular routes from Missouri to Madrid?

    Most travelers choose Kansas City - Madrid Barajas, Lambert-St Louis - Madrid Barajas or Columbia Regional - Madrid Barajas when deciding on the best route from Missouri to Madrid.

  • Can I find deals for flights from Missouri to Madrid that include hotel bookings?

    Yes. In addition to deals on Missouri to Madrid flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Madrid?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Madrid.

  • Can I find deals for business class flights from Missouri to Madrid?

    Yes. Cheapflights offers flight deals from Missouri to Madrid by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Madrid?

    Currently, February is the cheapest month in which you can book a flight from Missouri to Madrid (average of $628). Flying from Missouri to Madrid in June is currently the most expensive (average of $1,376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Madrid?

Book flights to Madrid if you plan to visit one of these locations
Getafe

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Top 9 airlines flying from Missouri to Madrid

Discover the top 9 airlines that operate flights from Missouri to Madrid. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 20, 2026.
AirlineCheapestAverageFlexibilityOn-time
Virgin AtlanticCheapest$382Average$657FlexibilityNo cancel feeOn-time72%
Air FranceCheapest$457Average$759FlexibilityNo cancel feeOn-time77%
British AirwaysCheapest$478Average$727FlexibilityNo cancel feeOn-time70%
LufthansaCheapest$482Average$830FlexibilityNo cancel feeOn-time76%
DeltaCheapest$488Average$850FlexibilityNo cancel feeOn-timeN/A
KLMCheapest$488Average$686FlexibilityNo cancel feeOn-time75%
IberiaCheapest$508Average$801FlexibilityNo cancel feeOn-time77%
American AirlinesCheapest$513Average$934FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$578Average$1,146FlexibilityNo cancel feeOn-time69%

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