$322+ Cheap flights from Missouri to Madrid, Spain (MAD)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/11. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MAD
Oct 15 — Oct 221
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Missouri to MadridExplore the most affordable flight options available from Missouri to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
Explore the most affordable flight options available from Missouri to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
This Gotogate deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/52:40 pm -
1 stop11h 10m
Wed 10/211:30 pm -
1 stop13h 50m
Deal found 9/14![Multiple Airlines logo]()
$557
This Flighttix deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/511:50 am -
1 stop13h 15m
Wed 10/2111:15 am -
1 stop15h 31m
Deal found 9/10![Lufthansa logo]()
$564
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/58:30 am -
1 stop16h 35m
Wed 10/211:30 pm -
2 stops29h 43m
Deal found 9/14![United Airlines logo]()
$565
This Booking.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:00 am -
1 stop16h 35m
Tue 10/611:45 am -
1 stop18h 32m
Deal found 9/12![British Airways logo]()
$566
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/510:29 am -
2 stops12h 51m
Wed 10/2112:45 pm -
2 stops27h 24m
Deal found 9/14![Delta logo]()
$570
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:00 am -
1 stop20h 55m
Wed 10/212:35 pm -
1 stop25h 10m
Deal found 9/10![Delta logo]()
$571
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/85:27 pm -
1 stop33h 18m
Tue 11/1712:20 pm -
1 stop35h 13m
Deal found 9/14![Delta logo]()
$572
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/281:09 pm -
1 stop11h 56m
Wed 10/1411:15 am -
2 stops17h 06m
Deal found 9/14![United Airlines logo]()
$572
This Air Canada deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:00 am -
2 stops19h 50m
Thu 10/221:30 pm -
2 stops39h 08m
Deal found 9/10![Air Canada logo]()
$573
This British Airways deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:35 pm -
1 stop13h 00m
Wed 10/2112:40 pm -
1 stop18h 19m
Deal found 9/11![British Airways logo]()
$573
This Gotogate deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/288:55 am -
1 stop16h 55m
Wed 10/145:55 am -
1 stop14h 30m
Deal found 9/14![Multiple Airlines logo]()
$574
This FlightHub deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/64:15 pm -
2 stops18h 15m
Tue 10/2010:25 am -
1 stop18h 32m
Deal found 9/13![British Airways logo]()
$577
Best flights from Missouri to MadridDiscover carefully curated flight deals from Missouri to Madrid that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
Discover carefully curated flight deals from Missouri to Madrid that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/166:40 pm -
2 stops31h 50m
Wed 3/31:25 pm -
2 stops32h 06m
Deal found 9/12![United Airlines logo]()
$569
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/510:29 am -
2 stops12h 51m
Wed 10/2112:45 pm -
2 stops27h 24m
Deal found 9/14![Delta logo]()
$570
This Finnair deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/319:22 am -
1 stop17h 28m
Tue 11/104:30 pm -
1 stop27h 09m
Deal found 9/10![Multiple Airlines logo]()
$635
This Expedia deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:40 pm -
2 stops21h 55m
Mon 11/236:05 am -
2 stops24h 05m
Deal found 9/13![Lufthansa logo]()
$718
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3010:40 am -
1 stop16h 45m
Wed 11/1812:40 pm -
1 stop16h 35m
Deal found 9/10![American Airlines logo]()
$781
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/51:09 pm -
1 stop11h 56m
Wed 10/2111:15 am -
2 stops17h 06m
Deal found 9/14![United Airlines logo]()
$570
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/85:27 pm -
1 stop33h 18m
Tue 11/1712:20 pm -
1 stop35h 13m
Deal found 9/14![Delta logo]()
$572
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/281:09 pm -
1 stop11h 56m
Wed 10/1411:15 am -
2 stops17h 06m
Deal found 9/14![United Airlines logo]()
$572
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:00 am -
2 stops18h 20m
Sun 11/229:20 am -
2 stops21h 35m
Deal found 9/13![Delta logo]()
$634
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/412:10 pm -
1 stop11h 40m
Wed 10/1411:15 am -
2 stops17h 06m
Deal found 9/12![United Airlines logo]()
$583
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2112:28 pm -
2 stops14h 02m
Fri 10/3010:50 am -
2 stops19h 04m
Deal found 9/11![Delta logo]()
$635
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:19 am -
2 stops17h 31m
Tue 10/206:20 am -
2 stops20h 26m
Deal found 9/14![United Airlines logo]()
$603
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:30 am -
1 stop13h 50m
Thu 10/156:00 am -
2 stops17h 54m
Deal found 9/11![Delta logo]()
$653
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:45 pm -
2 stops32h 45m
Tue 11/108:35 am -
2 stops19h 12m
Deal found 9/13![United Airlines logo]()
$610
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:00 am -
1 stop21h 45m
Wed 11/49:20 am -
2 stops18h 59m
Deal found 9/13![Delta logo]()
$664
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/111:50 am -
1 stop13h 15m
Tue 10/2011:15 am -
2 stops30h 11m
Deal found 9/11![United Airlines logo]()
$634
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/311:50 am -
1 stop13h 15m
Fri 10/2311:15 am -
1 stop34h 22m
Deal found 9/10![United Airlines logo]()
$636
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:10 am -
2 stops18h 50m
Tue 12/11:25 pm -
2 stops41h 10m
Deal found 9/11![United Airlines logo]()
$643
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:27 pm -
2 stops19h 08m
Tue 10/271:05 pm -
2 stops31h 35m
Deal found 9/13![Delta logo]()
$828
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/17:04 pm -
2 stops31h 26m
Mon 3/2211:00 am -
2 stops35h 24m
Deal found 9/13![United Airlines logo]()
$652
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/710:27 am -
2 stops23h 18m
Wed 10/211:30 pm -
1 stop13h 50m
Deal found 9/12![United Airlines logo]()
$652
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:00 am -
2 stops41h 00m
Wed 11/181:25 pm -
2 stops40h 33m
Deal found 9/11![United Airlines logo]()
$694
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/1211:30 am -
2 stops39h 00m
Sun 1/241:25 pm -
2 stops52h 30m
Deal found 9/12![United Airlines logo]()
$705
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:34 pm -
1 stop11h 41m
Tue 10/209:50 am -
1 stop13h 57m
Deal found 9/11![Delta logo]()
$1,210
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:30 am -
2 stops25h 10m
Mon 11/161:20 pm -
2 stops52h 28m
Deal found 9/10![United Airlines logo]()
$706
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:00 am -
2 stops19h 05m
Mon 10/58:25 am -
1 stop36h 00m
Deal found 9/12![United Airlines logo]()
$710
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:34 pm -
1 stop11h 41m
Mon 10/199:50 am -
1 stop19h 29m
Deal found 9/11![Delta logo]()
$1,324
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/29:00 am -
2 stops17h 30m
Tue 2/1611:15 am -
2 stops18h 38m
Deal found 9/12![United Airlines logo]()
$720
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1910:27 am -
2 stops14h 38m
Mon 11/211:00 am -
2 stops17h 40m
Deal found 9/14![United Airlines logo]()
$724
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/168:00 am -
2 stops17h 00m
Fri 2/196:05 am -
2 stops23h 48m
Deal found 9/12![United Airlines logo]()
$744
Last-minute flights from Missouri to MadridDiscover last-minute flight deals from Missouri to Madrid. Data last updated September 15, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Madrid. Data last updated September 15, 2026 and is based on user searches.
This Booking.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:00 am -
1 stop16h 35m
Tue 10/611:45 am -
1 stop18h 32m
Deal found 9/12![British Airways logo]()
$566
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/281:09 pm -
1 stop11h 56m
Wed 10/1411:15 am -
2 stops17h 06m
Deal found 9/14![United Airlines logo]()
$572
This Gotogate deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/288:55 am -
1 stop16h 55m
Wed 10/145:55 am -
1 stop14h 30m
Deal found 9/14![Multiple Airlines logo]()
$574
This Air Canada deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:00 am -
2 stops19h 50m
Thu 10/221:30 pm -
2 stops39h 08m
Deal found 9/10![Air Canada logo]()
$573
This Gotogate deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/52:40 pm -
1 stop11h 10m
Wed 10/211:30 pm -
1 stop13h 50m
Deal found 9/14![Multiple Airlines logo]()
$557
This Flighttix deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/511:50 am -
1 stop13h 15m
Wed 10/2111:15 am -
1 stop15h 31m
Deal found 9/10![Lufthansa logo]()
$564
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/58:30 am -
1 stop16h 35m
Wed 10/211:30 pm -
2 stops29h 43m
Deal found 9/14![United Airlines logo]()
$565
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:00 am -
1 stop23h 15m
Wed 10/2112:45 pm -
2 stops27h 24m
Deal found 9/14![Delta logo]()
$570
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:00 am -
2 stops17h 20m
Wed 10/212:35 pm -
1 stop34h 58m
Deal found 9/10![Delta logo]()
$571
This FlightHub deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/64:15 pm -
2 stops18h 15m
Tue 10/2010:25 am -
1 stop18h 32m
Deal found 9/13![British Airways logo]()
$577
This British Airways deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:35 pm -
1 stop13h 00m
Wed 10/2112:40 pm -
1 stop18h 19m
Deal found 9/11![British Airways logo]()
$573
This Orbitz deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/712:47 pm -
2 stops37h 53m
Wed 10/213:20 pm -
1 stop13h 54m
Deal found 9/12![Iberia logo]()
$577
One-way flights from Missouri to MadridSearch for one-way flight options from Missouri to Madrid. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
Search for one-way flight options from Missouri to Madrid. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
This Expedia deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/119:22 am -
2 stops39h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Air Canada logo]()
$322
This Expedia deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/1111:25 am -
1 stop14h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Iberia logo]()
$331
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/306:00 am -
2 stops18h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![United Airlines logo]()
$353
This Expedia deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/281:15 pm -
1 stop12h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![British Airways logo]()
$380
This deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2811:45 am -
1 stop14h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![United Airlines logo]()
$391
This SmartFares deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/306:30 pm -
1 stop32h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Virgin Atlantic logo]()
$400
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/76:00 am -
3 stops20h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![United Airlines logo]()
$403
This Flighttix deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/75:26 pm -
2 stops30h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Virgin Atlantic logo]()
$404
This KLM deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/276:07 pm -
2 stops14h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![KLM logo]()
$412
This Cheapflightsfares deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2710:59 am -
2 stops16h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Aer Lingus logo]()
$426
This Cheapflightsfares deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/207:27 am -
2 stops19h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Aer Lingus logo]()
$427
This Ovago deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/276:30 pm -
1 stop32h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Scandinavian Airlines logo]()
$435
Find flight deals from Missouri to Madrid
Keep the following information in mind while searching for Missouri to Madrid flight deals. Data was last updated September 15, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $557 (Gotogate) |
One-way from | $322 (Expedia) |
Popular in | June |
Cheapest in | February |
Average price | $1,107 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
Use the filters below to find and compare flights from Missouri to Madrid that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Kansas CityMadrid
MCI Kansas City - MAD Madrid Barajas
MCIMAD
Kansas City
Wed 12/30
6:00 am-7:45 am
2 stops18h 45m
Madrid Barajas
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$353
Kansas CityMadrid
MCI Kansas City - MAD Madrid Barajas
MCIMAD
Kansas City
Wed 12/30
6:30 pm-9:45 am
1 stop32h 15m
Madrid Barajas
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$400
Kansas CityMadrid
MCI Kansas City - MAD Madrid Barajas
MCIMAD
Kansas City
Sun 12/27
6:07 pm-4:05 pm
2 stops14h 58m
Madrid Barajas
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$412
St. LouisMadrid
STL Lambert-St Louis - MAD Madrid Barajas
STLMAD
Lambert-St Louis
Tue 10/27
10:59 am-9:55 am
2 stops16h 56m
Madrid Barajas
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$426
St. LouisMadrid
STL Lambert-St Louis - MAD Madrid Barajas
STLMAD
Lambert-St Louis
Sun 9/20
7:27 am-9:55 am
2 stops19h 28m
Madrid Barajas
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$427
Kansas CityMadrid
MCI Kansas City - MAD Madrid Barajas
MCIMAD
Kansas City
Sun 12/27
6:30 pm-9:45 am
1 stop32h 15m
Madrid Barajas
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$435
St. LouisMadrid
STL Lambert-St Louis - MAD Madrid Barajas
STLMAD
Lambert-St Louis
Mon 12/7
2:59 pm-10:50 am
3 stops36h 51m
Madrid Barajas
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$437
Kansas CityMadrid
MCI Kansas City - MAD Madrid Barajas
MCIMAD
Kansas City
Tue 12/1
7:05 am-9:55 am
2 stops19h 50m
Madrid Barajas
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$437
St. LouisMadrid
STL Lambert-St Louis - MAD Madrid Barajas
STLMAD
Lambert-St Louis
Mon 10/12
6:35 pm-9:45 am
3 stops32h 10m
Madrid Barajas
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$442
St. LouisMadrid
STL Lambert-St Louis - MAD Madrid Barajas
STLMAD
Lambert-St Louis
Thu 12/10
11:05 am-9:30 am
1 stop15h 25m
Madrid Barajas
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$453
Showing 1-10 of 57 resultsSorted by cheapest first
Best time to book a flight from Missouri to Madrid
Have a flexible travel schedule? Discover the best time to fly to Madrid from Missouri with our price prediction graph.
MCI-MAD
STL-MAD
SGF-MAD
COU-MAD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Madrid
USMO-MAD
MCI-MAD
STL-MAD
SGF-MAD
COU-MAD
What is the cheapest month to book a flight from Missouri to Madrid?
Currently, February is the cheapest month in which you can book a flight from Missouri to Madrid (average of $652). Flying from Missouri to Madrid in June is currently the most expensive (average of $1,376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Missouri to Madrid?
Airfare is below average for this route at the moment.
Missouri to Madrid flights typically cost between $854 and $1,188 in October.The cheapest round-trip price found within the last 5 days was $557 on Multiple Airlines (Oct 5-Oct 21).
How far ahead should I book a flight from Missouri to Madrid?
The price you pay for your flight from Missouri to Madrid may vary depending on when you book. For the best chance of a lower fare, look to book 45 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Madrid. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Madrid?
Book flights to Madrid if you plan to visit one of these locationsGetafe
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Missouri to Madrid
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Complete your trip
Complete your trip to Madrid by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Madrid by cabin class
Find flights from Missouri to Madrid, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Madrid
Explore flights to Madrid departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 15, 2026.
Missouri and Madrid flights
Browse other Missouri and Madrid flight options. Last updated on September 15, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Missouri to Madrid flights
Consider these flights traveling from Missouri to Madrid.
Top 7 airlines flying from Missouri to Madrid
Discover the top 7 airlines that operate flights from Missouri to Madrid. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$382 | Average$656 | FlexibilityNo cancel fee | On-time72% | |
| Cheapest$482 | Average$1,055 | FlexibilityNo cancel fee | On-time76% | |
| Cheapest$488 | Average$844 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$489 | Average$996 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$508 | Average$938 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$516 | Average$764 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$623 | Average$1,156 | FlexibilityNo cancel fee | On-time69% |