$363+ Cheap flights from Santa Fe (SAF) to Mexico City (MEX)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
SAF — MEX
Oct 16 — Oct 231
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Santa Fe to Mexico City
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Cheapest flights from Santa Fe to Mexico CityExplore the most affordable flight options available from Santa Fe to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2026.
Explore the most affordable flight options available from Santa Fe to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2026.
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:55 pm -
2 stops24h 05m
Tue 11/102:40 pm -
2 stops19h 32m
Deal found 9/16![United Airlines logo]()
$780
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/261:22 pm -
1 stop7h 48m
Sat 10/38:05 am -
1 stop6h 41m
Deal found 9/13![United Airlines logo]()
$817
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:26 pm -
1 stop15h 34m
Fri 11/65:39 am -
1 stop15h 05m
Deal found 9/15![American Airlines logo]()
$819
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/268:00 am -
2 stops14h 20m
Sat 10/35:00 am -
2 stops11h 48m
Deal found 9/13![American Airlines logo]()
$822
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:20 pm -
2 stops31h 50m
Fri 11/69:05 am -
1 stop12h 24m
Deal found 9/15![United Airlines logo]()
$823
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:26 pm -
1 stop15h 34m
Tue 11/105:39 am -
1 stop15h 05m
Deal found 9/16![American Airlines logo]()
$825
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:26 pm -
2 stops19h 39m
Thu 11/53:30 pm -
2 stops19h 15m
Deal found 9/14![United Airlines logo]()
$942
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:00 am -
2 stops21h 05m
Wed 11/45:50 pm -
2 stops16h 55m
Deal found 9/13![United Airlines logo]()
$967
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:26 pm -
1 stop15h 34m
Wed 11/48:06 am -
2 stops14h 50m
Deal found 9/13![American Airlines logo]()
$1,029
Best flights from Santa Fe to Mexico CityDiscover carefully curated flight deals from Santa Fe to Mexico City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 16, 2026.
Discover carefully curated flight deals from Santa Fe to Mexico City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 16, 2026.
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:55 pm -
2 stops24h 05m
Tue 11/109:05 am -
1 stop25h 07m
Deal found 9/16![United Airlines logo]()
$788
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:26 pm -
1 stop15h 34m
Tue 11/105:39 am -
1 stop15h 05m
Deal found 9/16![American Airlines logo]()
$825
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/261:22 pm -
1 stop7h 48m
Sat 10/38:05 am -
1 stop6h 41m
Deal found 9/13![United Airlines logo]()
$817
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:26 pm -
1 stop15h 34m
Wed 11/48:06 am -
2 stops14h 50m
Deal found 9/13![American Airlines logo]()
$1,029
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:26 pm -
2 stops19h 39m
Thu 11/53:30 pm -
2 stops19h 15m
Deal found 9/14![United Airlines logo]()
$942
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:00 am -
2 stops21h 05m
Wed 11/45:50 pm -
2 stops16h 55m
Deal found 9/13![United Airlines logo]()
$967
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:26 pm -
1 stop15h 34m
Thu 11/54:05 pm -
1 stop20h 28m
Deal found 9/14![American Airlines logo]()
$1,302
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1610:45 am -
2 stops12h 25m
Tue 1/53:30 pm -
2 stops19h 02m
Deal found 9/15![United Airlines logo]()
$1,311
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/177:00 am -
1 stop6h 15m
Tue 1/59:05 am -
1 stop12h 46m
Deal found 9/15![United Airlines logo]()
$1,923
Last-minute flights from Santa Fe to Mexico CityDiscover last-minute flight deals from Santa Fe to Mexico City. Data last updated September 16, 2026 and is based on user searches.
Discover last-minute flight deals from Santa Fe to Mexico City. Data last updated September 16, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/261:22 pm -
1 stop7h 48m
Sat 10/38:05 am -
1 stop6h 41m
Deal found 9/13![United Airlines logo]()
$817
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/268:00 am -
2 stops14h 20m
Sat 10/35:00 am -
2 stops11h 48m
Deal found 9/13![American Airlines logo]()
$822
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:00 am -
2 stops21h 05m
Wed 11/45:50 pm -
2 stops16h 55m
Deal found 9/13![United Airlines logo]()
$967
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:26 pm -
1 stop15h 34m
Wed 11/48:06 am -
2 stops14h 50m
Deal found 9/13![American Airlines logo]()
$1,029
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:26 pm -
2 stops19h 39m
Thu 11/53:30 pm -
2 stops19h 15m
Deal found 9/14![United Airlines logo]()
$942
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:55 pm -
2 stops24h 05m
Tue 11/102:40 pm -
2 stops19h 32m
Deal found 9/16![United Airlines logo]()
$780
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:26 pm -
1 stop15h 34m
Fri 11/65:39 am -
1 stop15h 05m
Deal found 9/15![American Airlines logo]()
$819
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:20 pm -
2 stops31h 50m
Fri 11/69:05 am -
1 stop12h 24m
Deal found 9/15![United Airlines logo]()
$823
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:26 pm -
1 stop15h 34m
Tue 11/105:39 am -
1 stop15h 05m
Deal found 9/16![American Airlines logo]()
$825
One-way flights from Santa Fe to Mexico CitySearch for one-way flight options from Santa Fe to Mexico City. Find affordable one-way fares based on user searches. Data last updated September 16, 2026.
Search for one-way flight options from Santa Fe to Mexico City. Find affordable one-way fares based on user searches. Data last updated September 16, 2026.
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:15 pm -
1 stop19h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![American Airlines logo]()
$363
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:00 pm -
2 stops14h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![United Airlines logo]()
$415
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:00 pm -
2 stops14h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![United Airlines logo]()
$449
Find flight deals from Santa Fe to Mexico City
Discover tips and strategies to find the most affordable flight options for your journey from Santa Fe (SAF) to Mexico City (MEX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $780 (United Airlines) |
One-way from | $363 (American Airlines) |
Popular in | May |
Cheapest in | November |
Average price | $678 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santa Fe to Mexico City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 16, 2026.
Use the filters below to find and compare flights from Santa Fe to Mexico City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Santa FeMexico City
SAF Santa Fe - MEX Mexico City Benito Juarez
SAFMEX
Santa Fe
Wed 10/21
7:15 pm-2:30 pm
1 stop19h 15m
Mexico City Benito Juarez
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$363
Santa FeMexico City
SAF Santa Fe - MEX Mexico City Benito Juarez
SAFMEX
Santa Fe
Wed 10/21
6:00 pm-8:35 am
2 stops14h 35m
Mexico City Benito Juarez
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$415
Quickest round-trip
Santa FeMexico City
SAF Santa Fe - MEX Mexico City Benito Juarez
SAFMEX
Santa Fe
Wed 9/30
10:00 am-9:10 pm
1 stop11h 10m
Mexico City Benito Juarez
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$449
Santa FeMexico City
SAF Santa Fe - MEX Mexico City Benito Juarez
SAFMEX
Santa Fe
Fri 10/30
5:55 pm-6:00 pm
2 stops24h 05m
Mexico City Benito Juarez
Tue 11/10
9:05 am-9:12 am
1 stop25h 07m
$788
Santa FeMexico City
SAF Santa Fe - MEX Mexico City Benito Juarez
SAFMEX
Santa Fe
Sat 9/26
1:22 pm-9:10 pm
1 stop7h 48m
Mexico City Benito Juarez
Sat 10/3
8:05 am-2:46 pm
1 stop6h 41m
$817
Santa FeMexico City
SAF Santa Fe - MEX Mexico City Benito Juarez
SAFMEX
Santa Fe
Fri 10/30
5:26 pm-9:00 am
1 stop15h 34m
Mexico City Benito Juarez
Tue 11/10
5:39 am-7:44 pm
1 stop15h 05m
$825
Santa FeMexico City
SAF Santa Fe - MEX Mexico City Benito Juarez
SAFMEX
Santa Fe
Thu 10/29
1:26 pm-9:05 am
2 stops19h 39m
Mexico City Benito Juarez
Thu 11/5
3:30 pm-9:45 am
2 stops19h 15m
$942
Santa FeMexico City
SAF Santa Fe - MEX Mexico City Benito Juarez
SAFMEX
Santa Fe
Wed 10/28
7:00 am-4:05 am
2 stops21h 05m
Mexico City Benito Juarez
Wed 11/4
5:50 pm-9:45 am
2 stops16h 55m
$967
Santa FeMexico City
SAF Santa Fe - MEX Mexico City Benito Juarez
SAFMEX
Santa Fe
Wed 10/28
5:26 pm-9:00 am
1 stop15h 34m
Mexico City Benito Juarez
Wed 11/4
8:06 am-9:56 pm
2 stops14h 50m
$1,029
Santa FeMexico City
SAF Santa Fe - MEX Mexico City Benito Juarez
SAFMEX
Santa Fe
Thu 10/29
5:26 pm-9:00 am
1 stop15h 34m
Mexico City Benito Juarez
Thu 11/5
4:05 pm-11:33 am
1 stop20h 28m
$1,302
Showing 1-10 of 12 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Santa Fe-Mexico City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Fe-Mexico City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Fe-Mexico City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santa Fe-Mexico City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Fe-Mexico City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santa Fe to Mexico City
Have a flexible travel schedule? Discover the best time to fly to Mexico City from Santa Fe with our price prediction graph.
SAF-MEX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Mexico City
Get insights into the airlines that provide service to Mexico City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico City. Reviews last updated September 16, 2026.
Get a feel of what it's like to fly with American Airlines from Santa Fe to Mexico City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.4
Entertainment
6.8
Crew
7.9
Comfort
7.2
Boarding
7.4
Overall
7.1
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Food
6.4
Entertainment
6.8
Crew
7.9
Comfort
7.2
Boarding
7.4
Overall
7.1
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Related info for your journey
Find useful and relevant information for your journey from Santa Fe to Mexico City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Mexico City?
Book flights to Mexico City if you plan to visit one of these locationsTaxco
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Other flights to Mexico City
Explore flights to Mexico City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 16, 2026.
Santa Fe and Mexico City flights
Browse other Santa Fe and Mexico City flight options. Last updated on September 16, 2026.
Other flights from Santa Fe
Browse through other flights departing from Santa Fe. Flights are based on user searches made on Cheapflights and were last updated on September 16, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Santa Fe to Mexico City
Discover the top airline that operate flights from Santa Fe to Mexico City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 16, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$558 | Average$768 | FlexibilityNo cancel fee | On-time71% |