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$278+ Cheap flights from Panama City, FL (ECP) to Mexico City (MEX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/1. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — MEX
juin 17 — juin 241
mar. 6/17
mar. 6/24
1 adult, Economy
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Cheap flight deals from Panama City to Mexico City

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Mexico City (MEX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated juin 12, 2025.

Round-trip from

$575
(Delta)

One-way from

$462
(American Airlines)

Popular in

October

Cheapest in

March

Average price

$664
From Panama City NW Florida Beaches to Mexico City Benito Juarez
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One-way flight from Panama City NW Florida Beaches to Mexico City Benito Juarez
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Highest demand for flights based on searches. 17% potential increase in price ($136 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($30 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Panama City to Mexico City

Cheapest flights from Panama City to Mexico City
Explore the most affordable flight options available from Panama City to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on juin 12, 2025.

This Aeromexico deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 11/199:23 amECP - MEX
2 stops13h 12mAeromexico
jeu. 11/272:00 pmMEX - ECP
1 stop8h 43mAeromexico
Deal found 6/12$524
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 11/206:00 amECP - MEX
2 stops12h 35mDelta
mer. 11/268:55 amMEX - ECP
2 stops13h 48mDelta
Deal found 6/9$529
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 7/287:24 pmECP - MEX
1 stop15h 56mAmerican Airlines
sam. 8/25:15 pmMEX - ECP
1 stop15h 01mAmerican Airlines
Deal found 6/11$585
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 11/2311:05 amECP - MEX
1 stop23h 00mUnited Airlines
jeu. 11/2710:05 amMEX - ECP
1 stop5h 58mUnited Airlines
Deal found 6/9$605
This WestJet deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure WestJet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 9/129:23 amECP - MEX
2 stops30h 37mWestJet
mar. 9/161:20 amMEX - ECP
2 stops17h 18mWestJet
Deal found 6/11$1,137

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to Mexico City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated juin 12, 2025.
Use the filters below to find and compare flights from Panama City to Mexico City that are best for you.

Fly from

Panama City

Fly to

Mexico City

Route

Depart

Return

Price

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

mer. 11/19

9:23 am-10:35 pm

2 stops13h 12m

Mexico City Benito Juarez

jeu. 11/27

2:00 pm-10:43 pm

1 stop8h 43m

$524

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

jeu. 11/20

6:00 am-6:35 pm

2 stops12h 35m

Mexico City Benito Juarez

mer. 11/26

8:55 am-10:43 pm

2 stops13h 48m

$529

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

lun. 7/28

7:24 pm-10:20 am

1 stop15h 56m

Mexico City Benito Juarez

sam. 8/2

5:15 pm-9:16 am

1 stop15h 01m

$585

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

dim. 11/23

11:05 am-10:05 am

1 stop23h 00m

Mexico City Benito Juarez

jeu. 11/27

10:05 am-4:03 pm

1 stop5h 58m

$605

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

ven. 9/12

9:23 am-3:00 pm

2 stops30h 37m

Mexico City Benito Juarez

mar. 9/16

1:20 am-7:38 pm

2 stops17h 18m

$1,137

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

lun. 12/1

7:45 am-8:05 pm

2 stops12h 20m

$278

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

lun. 7/21

6:30 am-3:40 pm

1 stop10h 10m

$292

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

mar. 12/2

6:53 am-7:35 pm

1 stop12h 42m

$337

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Best time to book a flight from Panama City to Mexico City

Have a flexible travel schedule? Discover the best time to fly to Mexico City from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Mexico City

What is the cheapest month to book a flight from Panama City, Florida to Mexico City?

Currently, May is the cheapest month in which you can book a flight from Panama City, Florida to Mexico City (average of $388). Flying from Panama City, Florida to Mexico City in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Mexico City by month

Plan your trip to Mexico City by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Mexico City ranges from 0.0 - 4.7 inches per month. July is typically the wettest month, when rainfall can reach 4.7 in. January is typically the driest time to visit Mexico City when rainfall is around 0.0 in.

Temperature in Mexico City by month

Plan your trip to Mexico City by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Mexico City, use this chart to help with planning. For those seeking warmer temperatures, May is the ideal time of year to visit, when temperatures reach an average of 66.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).

Reviews of airlines servicing Mexico City

Get insights into the airlines that provide service to Mexico City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico City. Reviews last updated juin 12, 2025.
Delta
8.0
Very good
7,950 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
8.0
Very good
7,950 reviews
Delta
8.0
Very good
7,950 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,950 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,950 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
WestJet
7.2
Good
2,868 reviews
Delta
8.0
Very good
7,950 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Mexico City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Panama City, Florida to Mexico City round-trip?

    Currently priced at $575, Delta will fly you from Panama City, Florida to Mexico City and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and United Airlines - these airlines can fly you to your destination from $585 and $640, respectively. Delta is 11% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Panama City to Mexico City that include hotel bookings?

    Yes. In addition to deals on Panama City to Mexico City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Mexico City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Mexico City.

  • Can I find deals for business class flights from Panama City to Mexico City?

    Yes. Cheapflights offers flight deals from Panama City to Mexico City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Mexico City?

    Currently, May is the cheapest month in which you can book a flight from Panama City, Florida to Mexico City (average of $388). Flying from Panama City, Florida to Mexico City in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

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Valle de Bravo

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Top 2 airlines flying from Panama City to Mexico City

Discover the top 2 airlines that operate flights from Panama City to Mexico City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated juin 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$362Average$600FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$546Average$626FlexibilityNo cancel feeOn-time69%

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