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Mexico City Federal District

$278+ Cheap flights from Panama City, FL (ECP) to Mexico City Federal District

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/1. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — MEX
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheap flight deals from Panama City to Mexico City Federal District

Keep the following information in mind while searching for Panama City to Mexico City Federal District flight deals. Data was last updated June 12, 2025.

Round-trip from

$575
(Delta)

One-way from

$462
(American Airlines)

Popular in

October

Cheapest in

March

Average price

$664
From Panama City NW Florida Beaches to Mexico City Federal District
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One-way flight from Panama City NW Florida Beaches to Mexico City Federal District
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Highest demand for flights based on searches. 17% potential increase in price ($136 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($30 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Panama City to Mexico City Federal District

Cheapest flights from Panama City to Mexico City Federal District
Explore the most affordable flight options available from Panama City to Mexico City Federal District. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Aeromexico deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/199:23 amECP - MEX
2 stops13h 12mAeromexico
Thu 11/272:00 pmMEX - ECP
1 stop8h 43mAeromexico
Deal found 6/12$524
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/206:00 amECP - MEX
2 stops12h 35mDelta
Wed 11/268:55 amMEX - ECP
2 stops13h 48mDelta
Deal found 6/9$529
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/287:24 pmECP - MEX
1 stop15h 56mAmerican Airlines
Sat 8/25:15 pmMEX - ECP
1 stop15h 01mAmerican Airlines
Deal found 6/11$585
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2311:05 amECP - MEX
1 stop23h 00mUnited Airlines
Thu 11/2710:05 amMEX - ECP
1 stop5h 58mUnited Airlines
Deal found 6/9$605
This WestJet deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure WestJet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/129:23 amECP - MEX
2 stops30h 37mWestJet
Tue 9/161:20 amMEX - ECP
2 stops17h 18mWestJet
Deal found 6/11$1,137

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to Mexico City Federal District that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Panama City to Mexico City Federal District that are best for you.

Fly from

Panama City

Fly to

Mexico City Federal District

Route

Depart

Return

Price

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Wed 11/19

9:23 am-10:35 pm

2 stops13h 12m

Mexico City Benito Juarez

Thu 11/27

2:00 pm-10:43 pm

1 stop8h 43m

$524

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Thu 11/20

6:00 am-6:35 pm

2 stops12h 35m

Mexico City Benito Juarez

Wed 11/26

8:55 am-10:43 pm

2 stops13h 48m

$529

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Mon 7/28

7:24 pm-10:20 am

1 stop15h 56m

Mexico City Benito Juarez

Sat 8/2

5:15 pm-9:16 am

1 stop15h 01m

$585

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Sun 11/23

11:05 am-10:05 am

1 stop23h 00m

Mexico City Benito Juarez

Thu 11/27

10:05 am-4:03 pm

1 stop5h 58m

$605

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Fri 9/12

9:23 am-3:00 pm

2 stops30h 37m

Mexico City Benito Juarez

Tue 9/16

1:20 am-7:38 pm

2 stops17h 18m

$1,137

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Mon 12/1

7:45 am-8:05 pm

2 stops12h 20m

$278

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Mon 7/21

6:30 am-3:40 pm

1 stop10h 10m

$292

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Tue 12/2

6:53 am-7:35 pm

1 stop12h 42m

$337

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Best time to book a flight from Panama City to Mexico City Federal District

Have a flexible travel schedule? Discover the best time to fly to Mexico City Federal District from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Mexico City Federal District

What is the cheapest month to book a flight from Panama City, Florida to Mexico City Federal District?

Currently, May is the cheapest month in which you can book a flight from Panama City, Florida to Mexico City Federal District (average of $388). Flying from Panama City, Florida to Mexico City Federal District in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Mexico City Federal District by month

Plan your trip to Mexico City Federal District by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Mexico City Federal District ranges from 0.0 - 4.7 inches per month. July is typically the wettest month, when rainfall can reach 4.7 in. January is typically the driest time to visit Mexico City Federal District when rainfall is around 0.0 in.

Temperature in Mexico City Federal District by month

Plan your trip to Mexico City Federal District by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Mexico City Federal District, use this chart to help with planning. For those seeking warmer temperatures, May is the ideal time of year to visit, when temperatures reach an average of 66.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).

Reviews of airlines servicing Mexico City Federal District

Get insights into the airlines that provide service to Mexico City Federal District. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico City Federal District. Reviews last updated June 12, 2025.
Delta
8.0
Very good
7,946 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
8.0
Very good
7,946 reviews
Delta
8.0
Very good
7,946 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,946 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,946 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
WestJet
7.2
Good
2,868 reviews
Delta
8.0
Very good
7,946 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Mexico City Federal District. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Mexico City Federal District?

    Panama City NW Florida Beaches (ECP), located 16.0 mi from the city center, is the airport you fly out of when you book flights from Panama City to Mexico City Federal District.

  • Can I find deals for flights from Panama City to Mexico City Federal District that include hotel bookings?

    Yes. In addition to deals on Panama City to Mexico City Federal District flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Mexico City Federal District?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Mexico City Federal District.

  • Can I find deals for business class flights from Panama City to Mexico City Federal District?

    Yes. Cheapflights offers flight deals from Panama City to Mexico City Federal District by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Mexico City Federal District?

    Currently, May is the cheapest month in which you can book a flight from Panama City, Florida to Mexico City Federal District (average of $388). Flying from Panama City, Florida to Mexico City Federal District in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama City to Mexico City Federal District

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Panama City to Mexico City Federal District

Discover the top 2 airlines that operate flights from Panama City to Mexico City Federal District. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$362Average$600FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$546Average$626FlexibilityNo cancel feeOn-time69%

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