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Mexico City Federal District

$578+ Cheap flights from Panama City, FL (ECP) to Mexico City Federal District

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/31. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — MEX
mar. 23 — mar. 301
lun. 3/23
lun. 3/30
1 adult, Economy
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Cheap flight deals from Panama City to Mexico City Federal District

Cheapest flights from Panama City to Mexico City Federal District
Explore the most affordable flight options available from Panama City to Mexico City Federal District. Find the lowest fares from popular airlines and budget airlines, with prices last updated on febrero 21, 2026.

This Aeromexico deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 8/317:45 am
ECP
-
MEX
1 stop14h 30m
Aeromexico
jue. 9/311:15 am
MEX
-
ECP
1 stop7h 22m
Aeromexico
Deal found 2/19$578
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/2811:15 am
ECP
-
MEX
1 stop10h 59m
Delta
lun. 8/39:40 am
MEX
-
ECP
2 stops12h 06m
Delta
Deal found 2/19$583
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/297:00 am
ECP
-
MEX
1 stop14h 45m
American Airlines
vie. 5/812:35 pm
MEX
-
ECP
1 stop10h 11m
American Airlines
Deal found 2/19$584
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 5/39:21 am
ECP
-
MEX
1 stop13h 29m
Delta
mié. 5/137:05 am
MEX
-
ECP
1 stop10h 31m
Delta
Deal found 2/19$604
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 9/67:45 am
ECP
-
MEX
1 stop7h 10m
Delta
sáb. 9/1210:50 am
MEX
-
ECP
2 stops10h 56m
Delta
Deal found 2/21$633
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/110:10 am
ECP
-
MEX
1 stop6h 30m
United Airlines
vie. 4/311:35 am
MEX
-
ECP
1 stop9h 24m
United Airlines
Deal found 2/19$644
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 9/611:46 am
ECP
-
MEX
1 stop7h 45m
American Airlines
sáb. 9/125:15 pm
MEX
-
ECP
1 stop16h 00m
American Airlines
Deal found 2/21$646
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/17:05 am
ECP
-
MEX
2 stops9h 40m
Delta
vie. 4/36:55 am
MEX
-
ECP
2 stops13h 27m
Delta
Deal found 2/19$649
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/287:00 am
ECP
-
MEX
2 stops14h 44m
American Airlines
lun. 8/37:00 am
MEX
-
ECP
1 stop14h 34m
American Airlines
Deal found 2/19$659

Find flight deals from Panama City to Mexico City Federal District

Keep the following information in mind while searching for Panama City to Mexico City Federal District flight deals. Data was last updated febrero 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$578
(Aeromexico)

One-way from

$412
(Delta)

Popular in

October

Cheapest in

September

Average price

$572
Provider with most accurate pricing for Panama City NW Florida Beaches-Mexico City Benito Juarez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-Mexico City Benito Juarez flights.
Search Deals
From Panama City NW Florida Beaches to Mexico City Federal District
Search Deals
One-way flight from Panama City NW Florida Beaches to Mexico City Federal District
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($77 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($35 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Mexico City Federal District that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 21, 2026.
Use the filters below to find and compare flights from Panama City to Mexico City Federal District that are best for you.

Fly from

Panama City

Fly to

Mexico City Federal District

Route

Depart

Return

Price

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

jue. 7/30

1:30 pm-9:14 pm

1 stop8h 44m

Mexico City Benito Juarez

lun. 8/3

7:05 am-7:36 pm

1 stop11h 31m

$578

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

mar. 7/28

7:45 am-3:30 pm

2 stops8h 45m

Mexico City Benito Juarez

lun. 8/3

8:40 am-10:46 pm

2 stops13h 06m

$583

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

mar. 7/28

9:00 am-1:15 pm

1 stop5h 15m

Mexico City Benito Juarez

lun. 8/3

9:35 am-9:57 pm

1 stop11h 22m

$584

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

mié. 4/29

7:21 am-10:20 pm

2 stops15h 59m

Mexico City Benito Juarez

vie. 5/8

12:35 pm-11:46 pm

1 stop10h 11m

$589

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

dom. 5/3

9:21 am-9:50 pm

1 stop13h 29m

Mexico City Benito Juarez

mar. 5/12

3:15 pm-10:51 pm

1 stop6h 36m

$604

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

dom. 5/3

5:49 am-1:55 pm

1 stop9h 06m

Mexico City Benito Juarez

mié. 5/13

7:05 am-6:36 pm

1 stop10h 31m

$604

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

dom. 5/3

5:49 am-1:55 pm

1 stop9h 06m

Mexico City Benito Juarez

mar. 5/12

9:05 am-4:54 pm

1 stop6h 49m

$604

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/18

Best time to book a flight from Panama City to Mexico City Federal District

Have a flexible travel schedule? Discover the best time to fly to Mexico City Federal District from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Mexico City Federal District

What is the cheapest month to book a flight from Panama City, Florida to Mexico City Federal District?

Currently, March is the cheapest month in which you can book a flight from Panama City, Florida to Mexico City Federal District (average of $387). Flying from Panama City, Florida to Mexico City Federal District in June is currently the most expensive (average of $580). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Mexico City Federal District

Get insights into the airlines that provide service to Mexico City Federal District. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico City Federal District. Reviews last updated febrero 21, 2026.
Get a feel of what it's like to fly with Delta and United Airlines from Panama City to Mexico City Federal District by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,228 reviews

Boarding

8.1

Overall

7.9

Crew

8.5

Entertainment

7.8

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
8,228 reviews
Delta
7.9
Good
8,228 reviews

Boarding

8.1

Overall

7.9

Crew

8.5

Entertainment

7.8

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
United Airlines
7.4
Good
9,335 reviews
Delta
7.9
Good
8,228 reviews

Boarding

8.1

Overall

7.9

Crew

8.5

Entertainment

7.8

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Mexico City Federal District. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Mexico City Federal District?

    Panama City NW Florida Beaches (ECP), located 16.0 mi from the city center, is the airport you fly out of when you book flights from Panama City to Mexico City Federal District.

  • How long is the flight from Panama City, Florida to Mexico City Federal District?

    Aeromexico, Delta, and United Airlines can get you from Panama City, Florida to Mexico City Federal District in just under 5h 15m. Your travel time can differ by up to 3h 30m. The distance from Panama City, Florida to Mexico City Federal District is about 1121 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Panama City to Mexico City Federal District that include hotel bookings?

    Yes. In addition to deals on Panama City to Mexico City Federal District flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Mexico City Federal District?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Mexico City Federal District.

  • Can I find deals for business class flights from Panama City to Mexico City Federal District?

    Yes. Cheapflights offers flight deals from Panama City to Mexico City Federal District by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Mexico City Federal District?

    Currently, March is the cheapest month in which you can book a flight from Panama City, Florida to Mexico City Federal District (average of $387). Flying from Panama City, Florida to Mexico City Federal District in June is currently the most expensive (average of $580). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Panama City to Mexico City Federal District

Discover the top 2 airlines that operate flights from Panama City to Mexico City Federal District. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$362Average$572FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$546Average$601FlexibilityNo cancel feeOn-time69%

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