In terms of precipitation, rainfall in Mexico City Federal District ranges from 0.0 - 4.7 inches per month. July is typically the wettest month, when rainfall can reach 4.7 in. January is typically the driest time to visit Mexico City Federal District when rainfall is around 0.0 in.

If weather is an important factor for your trip to Mexico City Federal District, use this chart to help with planning. For those seeking warmer temperatures, May is the ideal time of year to visit, when temperatures reach an average of 66.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).

What is the cheapest time of day to fly from ECP to DF?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City, Florida to Mexico City Federal District as you normally would.

What airport do you fly from for flights from Panama City to Mexico City Federal District?

Panama City NW Florida Beaches (ECP), located 16.0 mi from the city center, is the airport you fly out of when you book flights from Panama City to Mexico City Federal District.

How can I find direct flights from Panama City to Mexico City Federal District?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Mexico City Federal District.

Can I find deals for business class flights from Panama City to Mexico City Federal District?

Yes. Cheapflights offers flight deals from Panama City to Mexico City Federal District by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$536+ Flights from Panama City, FL to Mexico City Federal District

Q: How much does it cost to fly round-trip from Panama City, Florida to Mexico City Federal District?

Airfare is below average for this route at the moment. Panama City, Florida to Mexico City Federal District flights typically cost between $864 and $1,079 in December. The cheapest round-trip price found within the last 3 days was $536 on Delta (Dec 31-Jan 15).

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Panama City to Mexico City Federal District with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Panama City to Mexico City Federal District

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$536 (Delta)
Popular in	October
Cheapest in	May
Average price	$540

Provider with most accurate pricing for Panama City NW Florida Beaches-Mexico City Benito Juarez flight deals.

Search Deals

Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-Mexico City Benito Juarez flights.

Search Deals

From Panama City NW Florida Beaches to Mexico City Federal District

Search Deals

Highest demand for flights based on searches. 15% potential increase in price ($121 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 4% potential price decrease ($29 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in September 2025

Search Deals

Find flight deals from Panama City to Mexico City Federal District

Cheapest flights from Panama City to Mexico City Federal District
Explore the most affordable flight options available from Panama City to Mexico City Federal District. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 30, 2025.

Wed 12/3111:06 amECP - MEX

1 stop10h 44mDelta

Thu 1/154:45 pmMEX - ECP

1 stop15h 35mDelta

Deal found 9/29

$536

Tue 12/302:04 pmECP - MEX

1 stop6h 01mDelta

Wed 1/148:55 amMEX - ECP

2 stops13h 47mDelta

Deal found 9/29

$541

Mon 12/16:30 amECP - MEX

1 stop12h 25mUnited Airlines

Thu 12/47:50 amMEX - ECP

1 stop6h 08mUnited Airlines

Deal found 9/30

$562

Tue 12/302:04 pmECP - MEX

1 stop7h 46mDelta

Sun 1/118:55 amMEX - ECP

2 stops13h 47mDelta

Deal found 9/29

$564

Wed 10/223:41 pmECP - MEX

2 stops19h 14mAmerican Airlines

Sat 11/88:00 amMEX - ECP

1 stop11h 16mAmerican Airlines

Deal found 9/29

$578

Mon 11/35:55 pmECP - MEX

2 stops17h 25mAmerican Airlines

Sat 11/812:30 pmMEX - ECP

2 stops11h 23mAmerican Airlines

Deal found 9/28

$587

Wed 12/312:55 pmECP - MEX

1 stop9h 15mUnited Airlines

Tue 1/137:50 amMEX - ECP

1 stop8h 22mUnited Airlines

Deal found 9/29

$632

Wed 12/312:10 pmECP - MEX

2 stops22h 05mUnited Airlines

Thu 1/153:20 pmMEX - ECP

1 stop6h 39mUnited Airlines

Deal found 9/29

$637

Tue 12/304:45 pmECP - MEX

1 stop24h 00mUnited Airlines

Mon 1/125:45 amMEX - ECP

1 stop6h 17mUnited Airlines

Deal found 9/29

$644

Wed 12/316:15 amECP - MEX

1 stop12h 40mUnited Airlines

Fri 1/910:05 amMEX - ECP

1 stop11h 54mUnited Airlines

Deal found 9/29

$652

Best flights from Panama City to Mexico City Federal District
Discover carefully curated flight deals from Panama City to Mexico City Federal District that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 30, 2025.

Mon 12/16:30 amECP - MEX

1 stop12h 25mUnited Airlines

Thu 12/47:50 amMEX - ECP

1 stop6h 08mUnited Airlines

Deal found 9/30

$562

Wed 10/223:41 pmECP - MEX

2 stops19h 14mAmerican Airlines

Sat 11/812:30 pmMEX - ECP

2 stops11h 23mAmerican Airlines

Deal found 9/29

$578

Mon 11/35:55 pmECP - MEX

2 stops17h 25mAmerican Airlines

Sat 11/88:00 amMEX - ECP

1 stop11h 16mAmerican Airlines

Deal found 9/28

$587

Mon 12/16:47 amECP - MEX

2 stops17h 23mAmerican Airlines

Thu 12/46:45 amMEX - ECP

2 stops14h 31mAmerican Airlines

Deal found 9/30

$662

Mon 11/35:00 pmECP - MEX

2 stops21h 45mWestJet

Fri 11/71:05 amMEX - ECP

2 stops35h 42mWestJet

Deal found 9/28

$1,569

Thu 10/303:00 pmECP - MEX

1 stop19h 05mUnited Airlines

Sat 11/87:50 amMEX - ECP

1 stop5h 57mUnited Airlines

Deal found 9/30

$800

Thu 10/306:44 amECP - MEX

2 stops17h 06mAmerican Airlines

Sat 11/812:35 pmMEX - ECP

2 stops11h 18mAmerican Airlines

Deal found 9/30

$827

Sat 12/204:09 pmECP - MEX

2 stops17h 46mAmerican Airlines

Wed 12/248:00 amMEX - ECP

1 stop6h 58mAmerican Airlines

Deal found 9/30

$989

Last-minute flights from Panama City to Mexico City Federal District
Discover last-minute flight deals from Panama City to Mexico City Federal District. Data last updated September 30, 2025 and is based on user searches.

Tue 9/306:30 amECP - MEX

1 stop10h 10mUnited Airlines

Tue 10/146:30 amMEX - ECP

1 stop14h 18mUnited Airlines

Deal found 9/30

$822

Tue 9/307:00 amECP - MEX

2 stops32h 10mWestJet

Mon 10/1312:10 amMEX - ECP

2 stops35h 30mWestJet

Deal found 9/30

$1,753

Wed 10/13:53 pmECP - MEX

1 stop21h 17mAmerican Airlines

Wed 10/82:00 pmMEX - ECP

2 stops19h 13mAmerican Airlines

Deal found 9/30

$882

Wed 10/17:00 amECP - MEX

1 stop8h 10mDelta

Wed 10/83:50 pmMEX - ECP

1 stop6h 20mDelta

Deal found 9/30

$902

Wed 10/17:00 amECP - MEX

2 stops32h 10mWestJet

Tue 10/712:10 amMEX - ECP

2 stops31h 34mWestJet

Deal found 9/30

$2,180

Wed 10/223:41 pmECP - MEX

2 stops19h 14mAmerican Airlines

Sat 11/88:00 amMEX - ECP

1 stop11h 16mAmerican Airlines

Deal found 9/29

$578

Wed 10/227:10 amECP - MEX

2 stops32h 00mWestJet

Fri 11/71:05 amMEX - ECP

2 stops22h 05mWestJet

Deal found 9/29

$1,599

Thu 10/303:00 pmECP - MEX

1 stop19h 05mUnited Airlines

Sat 11/87:50 amMEX - ECP

1 stop5h 57mUnited Airlines

Deal found 9/30

$800

Thu 10/301:25 pmECP - MEX

2 stops35h 36mWestJet

Fri 11/712:25 amMEX - ECP

2 stops39h 01mWestJet

Deal found 9/30

$1,896

Cheapflights Fare Finder

Use the filters below to find and compare flights from Panama City to Mexico City Federal District that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Mon 12/1

6:30 am-6:55 pm

1 stop12h 25m

Mexico City Benito Juarez

Thu 12/4

7:50 am-1:58 pm

1 stop6h 08m

$562

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Wed 10/22

3:41 pm-9:55 am

2 stops19h 14m

Mexico City Benito Juarez

Sat 11/8

12:30 pm-11:53 pm

2 stops11h 23m

$578

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Mon 11/3

5:55 pm-11:20 am

2 stops17h 25m

Mexico City Benito Juarez

Sat 11/8

8:00 am-7:16 pm

1 stop11h 16m

$587

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Mon 12/1

6:47 am-12:10 am

2 stops17h 23m

Mexico City Benito Juarez

Thu 12/4

6:45 am-9:16 pm

2 stops14h 31m

$662

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Thu 10/30

3:00 pm-9:05 am

1 stop19h 05m

Mexico City Benito Juarez

Sat 11/8

7:50 am-1:47 pm

1 stop5h 57m

$800

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Thu 10/30

6:44 am-10:50 pm

2 stops17h 06m

Mexico City Benito Juarez

Sat 11/8

12:35 pm-11:53 pm

2 stops11h 18m

$827

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Sat 12/20

4:09 pm-9:55 am

2 stops17h 46m

Mexico City Benito Juarez

Wed 12/24

8:00 am-2:58 pm

1 stop6h 58m

$989

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Mon 11/3

5:00 pm-2:45 pm

2 stops21h 45m

Mexico City Benito Juarez

Fri 11/7

1:05 am-12:47 pm

2 stops35h 42m

$1,569

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/30

Best time to book a flight from Panama City to Mexico City Federal District

Have a flexible travel schedule? Discover the best time to fly to Mexico City Federal District from Panama City with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Mexico City Federal District

What is the cheapest month to book a flight from Panama City, Florida to Mexico City Federal District?

Currently, May is the cheapest month in which you can book a flight from Panama City, Florida to Mexico City Federal District (average of $388). Flying from Panama City, Florida to Mexico City Federal District in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Panama City, Florida to Mexico City Federal District?

Reviews of airlines servicing Mexico City Federal District

Get a feel of what it's like to fly with Delta and United Airlines from Panama City to Mexico City Federal District by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,964 reviews

Reviews

1 / 20

6.0

Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Delta

8.0

Very good

7,964 reviews

Delta

8.0

Very good

7,964 reviews

Reviews

1 / 20

6.0

Good

pilar,May 2025

RSW - ATL

United Airlines

7.4

Good

8,931 reviews

Delta

8.0

Very good

7,964 reviews

Reviews

1 / 20

6.0

Good

pilar,May 2025

RSW - ATL

Related info for your journey

What airport do you fly from for flights from Panama City to Mexico City Federal District?
Panama City NW Florida Beaches (ECP), located 16.0 mi from the city center, is the airport you fly out of when you book flights from Panama City to Mexico City Federal District.
How long is the flight from Panama City, Florida to Mexico City Federal District?
United Airlines and American Airlines can get you from Panama City, Florida to Mexico City Federal District in just under 12h 25m. Your travel time can differ by up to 6h 49m. The distance from Panama City, Florida to Mexico City Federal District is about 1121 mi. This flight may include one or multiple stops.
Can I find deals for flights from Panama City to Mexico City Federal District that include hotel bookings?
Yes. In addition to deals on Panama City to Mexico City Federal District flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Panama City to Mexico City Federal District?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Mexico City Federal District.
Can I find deals for business class flights from Panama City to Mexico City Federal District?
Yes. Cheapflights offers flight deals from Panama City to Mexico City Federal District by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Panama City, Florida to Mexico City Federal District?
Currently, May is the cheapest month in which you can book a flight from Panama City, Florida to Mexico City Federal District (average of $388). Flying from Panama City, Florida to Mexico City Federal District in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Panama City to Mexico City Federal District

Miami to Mexico City flights

Miami to Cancún flights

Orlando to Cancún flights

Fort Lauderdale to Cancún flights

Tampa to Cancún flights

Tampa to Mexico City flights

Orlando to Mexico City flights

Miami to Cozumel flights

Orlando to Cozumel flights

Jacksonville to Cancún flights

Fort Lauderdale to Cozumel flights

Tampa to Cozumel flights

West Palm Beach to Cancún flights

Jacksonville to Cozumel flights

Fort Lauderdale to Mexico City flights

Orlando to Guadalajara flights

Miami to Mérida flights

Miami to San José del Cabo flights

Tampa to San José del Cabo flights

Fort Lauderdale to San José del Cabo flights

West Palm Beach to Mexico City flights

Orlando to San José del Cabo flights

Orlando to Puerto Vallarta flights

Tampa to Puerto Vallarta flights

Pensacola to Cancún flights

Fort Myers to Cancún flights

Miami to Puerto Vallarta flights

Miami to Guadalajara flights

Tampa to Mexico City flights

Fort Lauderdale to Puerto Vallarta flights

Fort Myers to Cozumel flights

Orlando to Monterrey flights

Miami to Monterrey flights

Sarasota to Cancún flights

West Palm Beach to San José del Cabo flights

Panama City to Cancún flights

Miami to Oaxaca flights

West Palm Beach to Cozumel flights

Jacksonville to Mexico City flights

Pensacola to Cozumel flights

West Palm Beach to Puerto Vallarta flights

Miami to Santiago de Querétaro flights

Pensacola to Mexico City flights

Fort Myers to Puerto Vallarta flights

Miami to San Luis Potosí flights

Fort Myers to Mexico City flights

Jacksonville to Puerto Vallarta flights

Fort Lauderdale to Mexico City flights

Orlando to Oaxaca flights

Fort Myers to San José del Cabo flights

Top 2 airlines flying from Panama City to Mexico City Federal District

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$362	Average$577	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$546	Average$601	FlexibilityNo cancel fee	On-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$536+ Cheap flights from Panama City, FL (ECP) to Mexico City Federal District

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/31. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Panama City to Mexico City Federal District with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Panama City to Mexico City Federal District

Keep the following information in mind while searching for Panama City to Mexico City Federal District flight deals. Data was last updated September 30, 2025.

Most accurate provider

Most trusted provider

Round-trip from

Popular in

Cheapest in

Average price

Find flight deals from Panama City to Mexico City Federal District

Cheapest flights from Panama City to Mexico City Federal DistrictExplore the most affordable flight options available from Panama City to Mexico City Federal District. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 30, 2025.

Explore the most affordable flight options available from Panama City to Mexico City Federal District. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 30, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Panama City to Mexico City Federal District that are best for you.

Best time to book a flight from Panama City to Mexico City Federal District

Have a flexible travel schedule? Discover the best time to fly to Mexico City Federal District from Panama City with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Mexico City Federal District

What is the cheapest month to book a flight from Panama City, Florida to Mexico City Federal District?

How much does it cost to fly round-trip from Panama City, Florida to Mexico City Federal District?

Reviews of airlines servicing Mexico City Federal District

Get a feel of what it's like to fly with Delta and United Airlines from Panama City to Mexico City Federal District by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Mexico City Federal District. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Panama City to Mexico City Federal District?

How long is the flight from Panama City, Florida to Mexico City Federal District?

Can I find deals for flights from Panama City to Mexico City Federal District that include hotel bookings?

How can I find direct flights from Panama City to Mexico City Federal District?

Can I find deals for business class flights from Panama City to Mexico City Federal District?

What is the cheapest month to book a flight from Panama City, Florida to Mexico City Federal District?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama City to Mexico City Federal District

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Panama City to Mexico City Federal District

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Panama City to Mexico City Federal District
Explore the most affordable flight options available from Panama City to Mexico City Federal District. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 30, 2025.