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Mesa

$116+ Cheap flights from Syracuse (SYR) to Mesa, AZ

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/27. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — PHX
Feb 13 — Feb 201
Fri 2/13
Fri 2/20
1 adult, Economy
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Cheap flight deals from Syracuse to Mesa

Keep the following information in mind while searching for Syracuse to Mesa flight deals. Data was last updated January 14, 2026.

Round-trip from

$313
(American Airlines)

One-way from

$116
(Booking.com)

Popular in

December

Cheapest in

July

Average price

$410
From Syracuse Hancock Intl to Mesa
Search Deals
One-way flight from Syracuse Hancock Intl to Mesa
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($24 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Syracuse to Mesa

Cheapest flights from Syracuse to Mesa
Explore the most affordable flight options available from Syracuse to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 14, 2026.

This American Airlines deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/206:11 pm
SYR
-
PHX
1 stop8h 56m
American Airlines
Tue 3/2411:35 pm
PHX
-
SYR
1 stop9h 18m
American Airlines
Deal found 1/13$313
This Delta deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:00 am
SYR
-
PHX
1 stop9h 31m
Delta
Wed 10/2111:10 pm
PHX
-
SYR
1 stop6h 47m
Delta
Deal found 1/12$318
This Delta deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/24:32 pm
SYR
-
PHX
1 stop8h 17m
Delta
Mon 2/911:53 pm
PHX
-
SYR
1 stop9h 12m
Delta
Deal found 1/12$319
This Delta deal was found by Cheapflights users on 1/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/304:32 pm
SYR
-
PHX
1 stop8h 17m
Delta
Wed 2/41:55 pm
PHX
-
SYR
1 stop7h 56m
Delta
Deal found 1/11$320
This American Airlines deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/283:03 pm
SYR
-
PHX
2 stops10h 54m
American Airlines
Thu 2/512:22 pm
PHX
-
SYR
1 stop9h 05m
American Airlines
Deal found 1/12$325
This United Airlines deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:07 am
SYR
-
PHX
1 stop8h 13m
United Airlines
Mon 9/2111:59 pm
PHX
-
SYR
1 stop6h 45m
United Airlines
Deal found 1/12$327
This United Airlines deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:15 am
SYR
-
PHX
2 stops11h 06m
United Airlines
Mon 5/1111:12 am
PHX
-
SYR
1 stop6h 36m
United Airlines
Deal found 1/13$332
This Kiwi.com deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/68:58 am
SYR
-
PHX
1 stop13h 51m
Multiple Airlines
Tue 2/1011:59 pm
PHX
-
SYR
2 stops36h 16m
Multiple Airlines
Deal found 1/12$336
This Delta deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/16:00 am
SYR
-
PHX
1 stop8h 29m
Delta
Thu 2/511:53 pm
PHX
-
SYR
1 stop9h 12m
Delta
Deal found 1/12$340
This Delta deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/311:43 am
SYR
-
PHX
1 stop12h 57m
Delta
Tue 2/101:55 pm
PHX
-
SYR
1 stop7h 56m
Delta
Deal found 1/12$341
This Expedia deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/21:43 pm
SYR
-
PHX
1 stop10h 12m
Multiple Airlines
Wed 3/48:56 pm
PHX
-
SYR
2 stops17h 19m
Multiple Airlines
Deal found 1/13$343
This American Airlines deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/2612:06 pm
SYR
-
PHX
1 stop10h 23m
American Airlines
Thu 1/2910:45 pm
PHX
-
SYR
1 stop13h 53m
American Airlines
Deal found 1/12$345

Cheapflights Fare Finder

 
Customize your flight search to find flights from Syracuse to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 14, 2026.
Use the filters below to find and compare flights from Syracuse to Mesa that are best for you.

Fly from

Syracuse

Fly to

Mesa

Route

Depart

Return

Price

SyracusePhoenix

SYR - PHX

SYRPHX

Syracuse Hancock Intl

Sat 1/31

6:00 am-12:29 pm

1 stop8h 29m

Phoenix Sky Harbor Intl

Thu 2/5

11:53 pm-11:05 am

1 stop9h 12m

$320

SyracusePhoenix

SYR - PHX

SYRPHX

Syracuse Hancock Intl

Sat 1/31

3:00 pm-11:46 pm

1 stop10h 46m

Phoenix Sky Harbor Intl

Tue 2/3

6:00 am-5:29 pm

1 stop9h 29m

$320

SyracusePhoenix

SYR - PHX

SYRPHX

Syracuse Hancock Intl

Sat 1/31

6:00 am-12:29 pm

1 stop8h 29m

Phoenix Sky Harbor Intl

Mon 2/2

11:53 pm-11:05 am

1 stop9h 12m

$320

SyracusePhoenix

SYR - PHX

SYRPHX

Syracuse Hancock Intl

Sun 2/1

6:00 am-12:29 pm

1 stop8h 29m

Phoenix Sky Harbor Intl

Wed 2/4

12:45 pm-11:13 pm

1 stop8h 28m

$340

SyracusePhoenix

SYR - PHX

SYRPHX

Syracuse Hancock Intl

Mon 2/23

5:00 pm-10:46 pm

1 stop7h 46m

Phoenix Sky Harbor Intl

Mon 3/2

11:50 pm-11:00 am

1 stop9h 10m

$358

SyracusePhoenix

SYR - PHX

SYRPHX

Syracuse Hancock Intl

Tue 2/3

5:20 am-10:40 pm

1 stop19h 20m

Phoenix Sky Harbor Intl

Mon 2/9

11:53 pm-11:05 am

1 stop9h 12m

$362

SyracusePhoenix

SYR - PHX

SYRPHX

Syracuse Hancock Intl

Sun 4/5

5:20 pm-9:54 pm

1 stop7h 34m

Phoenix Sky Harbor Intl

Thu 4/9

11:55 pm-11:07 am

1 stop8h 12m

$368

SyracusePhoenix

SYR - PHX

SYRPHX

Syracuse Hancock Intl

Thu 1/29

6:15 am-11:44 pm

2 stops19h 29m

Phoenix Sky Harbor Intl

Mon 2/2

11:53 pm-11:05 am

1 stop9h 12m

$375

SyracusePhoenix

SYR - PHX

SYRPHX

Syracuse Hancock Intl

Thu 1/29

6:15 am-11:44 pm

2 stops19h 29m

Phoenix Sky Harbor Intl

Tue 2/3

1:55 pm-11:51 pm

1 stop7h 56m

$375

SyracusePhoenix

SYR - PHX

SYRPHX

Syracuse Hancock Intl

Thu 1/29

6:15 am-11:44 pm

2 stops19h 29m

Phoenix Sky Harbor Intl

Wed 2/4

11:53 pm-11:05 am

1 stop9h 12m

$375

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/12

Showing 1-10 of 18 results
1
2

Best time to book a flight from Syracuse to Mesa

Have a flexible travel schedule? Discover the best time to fly to Mesa from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to Mesa

How far ahead should I book a flight from Syracuse to Mesa?

Use this chart to determine the optimal time to book a round-trip flight from Syracuse to Mesa. Price data was last updated on January 9, 2026.

To ensure you get the cheapest price possible for a flight from Syracuse to Mesa, you should look to book at least 68 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Syracuse to Mesa?

Currently, November is the cheapest month in which you can book a flight from Syracuse to Mesa (average of $146). Flying from Syracuse to Mesa in October is currently the most expensive (average of $269). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Mesa

Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated January 14, 2026.
Read through reviews of airlines operating flights from Syracuse to Mesa, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,040 reviews

Entertainment

7.8

Comfort

7.9

Food

7.2

Boarding

8.1

Overall

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
7.9
Good
8,040 reviews
Delta
7.9
Good
8,040 reviews

Entertainment

7.8

Comfort

7.9

Food

7.2

Boarding

8.1

Overall

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
9,156 reviews
Delta
7.9
Good
8,040 reviews

Entertainment

7.8

Comfort

7.9

Food

7.2

Boarding

8.1

Overall

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
11,122 reviews
Delta
7.9
Good
8,040 reviews

Entertainment

7.8

Comfort

7.9

Food

7.2

Boarding

8.1

Overall

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
JetBlue
7.2
Good
2,884 reviews
Delta
7.9
Good
8,040 reviews

Entertainment

7.8

Comfort

7.9

Food

7.2

Boarding

8.1

Overall

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Frontier
5.7
Fair
3,056 reviews
Delta
7.9
Good
8,040 reviews

Entertainment

7.8

Comfort

7.9

Food

7.2

Boarding

8.1

Overall

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Syracuse to Mesa?

    If you book a flight to Mesa from Syracuse, you will be flying from Hancock Intl, which is the city’s only airport. Syracuse Hancock Intl (SYR) is located 4.8 mi from the center of Syracuse. There are 0 flights from Hancock Intl to Mesa per day from 5 different airlines.

  • How long is the flight from Syracuse to Mesa?

    Departing from Syracuse to Mesa will take you 10h 24m. There are 2039 mi between Syracuse and Mesa. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Syracuse to Mesa one-way?

    $108 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on JetBlue and Delta, with prices starting from $121 and $138, respectively.

  • Can I find deals for flights from Syracuse to Mesa that include hotel bookings?

    Yes. In addition to deals on Syracuse to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to Mesa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to Mesa.

  • Can I find deals for business class flights from Syracuse to Mesa?

    Yes. Cheapflights offers flight deals from Syracuse to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to Mesa?

    Currently, November is the cheapest month in which you can book a flight from Syracuse to Mesa (average of $146). Flying from Syracuse to Mesa in October is currently the most expensive (average of $269). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Syracuse to Mesa

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Syracuse to Mesa

Discover the top 5 airlines that operate flights from Syracuse to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 14, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$138Average$350FlexibilityNo cancel feeOn-time62%
JetBlueCheapest$161Average$281FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$264Average$392FlexibilityNo cancel feeOn-time71%
DeltaCheapest$272Average$392FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$308Average$453FlexibilityNo cancel feeOn-time69%

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