$153+ Cheap flights from San Diego (SAN) to Medellín
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/7. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — MDE
Mar 14 — Mar 211
1 adult, Economy
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Find cheap flights from San Diego to Medellín with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Diego to Medellín
Cheapest
Best
Last-minute
One-way
Cheapest flights from San Diego to MedellínExplore the most affordable flight options available from San Diego to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 12, 2026.
Explore the most affordable flight options available from San Diego to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 12, 2026.
This flugladen.de deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure flugladen.de is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/68:30 pm
SAN
- MDE
1 stop34h 40m
Multiple Airlines
Sun 4/198:00 pm
MDE
- SAN
1 stop26h 04m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$382
This Trip.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/289:58 pm
SAN
- MDE
1 stop33h 12m
Multiple Airlines
Sat 4/48:00 pm
MDE
- SAN
1 stop18h 52m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$390
This Avianca deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/99:10 pm
SAN
- MDE
1 stop12h 40m
Multiple Airlines
Mon 3/164:45 am
MDE
- SAN
2 stops16h 20m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$392
This oojo deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1810:25 am
SAN
- MDE
1 stop22h 55m
Multiple Airlines
Sun 5/318:00 pm
MDE
- SAN
1 stop19h 01m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$406
This Avianca deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/37:50 pm
SAN
- MDE
2 stops14h 05m
Multiple Airlines
Sun 3/86:25 am
MDE
- SAN
2 stops14h 40m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$408
This oojo deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/610:25 am
SAN
- MDE
1 stop22h 55m
Multiple Airlines
Thu 5/78:00 pm
MDE
- SAN
1 stop18h 48m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$409
This Trip.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/248:00 am
SAN
- MDE
1 stop23h 10m
Multiple Airlines
Wed 5/2710:40 pm
MDE
- SAN
1 stop16h 21m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$411
This oojo deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/77:00 am
SAN
- MDE
1 stop26h 20m
Multiple Airlines
Tue 4/2110:40 pm
MDE
- SAN
1 stop16h 08m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$418
Best flights from San Diego to MedellínDiscover carefully curated flight deals from San Diego to Medellín that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 12, 2026.
Discover carefully curated flight deals from San Diego to Medellín that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 12, 2026.
This Trip.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/289:58 pm
SAN
- MDE
1 stop33h 12m
Multiple Airlines
Sat 4/48:00 pm
MDE
- SAN
1 stop18h 52m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$390
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/210:30 am
SAN
- MDE
1 stop8h 35m
United Airlines
Wed 3/410:45 am
MDE
- SAN
1 stop10h 48m
United Airlines
Deal found 2/8![United Airlines logo]()
$477
This Avianca deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/99:10 pm
SAN
- MDE
1 stop12h 40m
Multiple Airlines
Mon 3/164:45 am
MDE
- SAN
2 stops16h 20m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$392
This oojo deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/289:58 pm
SAN
- MDE
1 stop33h 12m
Multiple Airlines
Sun 4/121:00 pm
MDE
- SAN
1 stop24h 46m
Multiple Airlines
Deal found 2/8![Multiple Airlines logo]()
$444
This oojo deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/243:48 pm
SAN
- MDE
1 stop27h 52m
Multiple Airlines
Fri 4/101:00 pm
MDE
- SAN
1 stop24h 46m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$460
This oojo deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/293:48 pm
SAN
- MDE
1 stop27h 37m
Multiple Airlines
Sun 4/121:00 pm
MDE
- SAN
1 stop24h 46m
Multiple Airlines
Deal found 2/8![Multiple Airlines logo]()
$460
This oojo deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/179:05 pm
SAN
- MDE
2 stops18h 45m
Multiple Airlines
Tue 3/318:00 pm
MDE
- SAN
1 stop18h 52m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$461
This Travelocity deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/87:45 pm
SAN
- MDE
2 stops15h 25m
Multiple Airlines
Wed 8/196:35 am
MDE
- SAN
1 stop15h 45m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$463
This oojo deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/611:05 am
SAN
- MDE
2 stops24h 05m
Multiple Airlines
Thu 5/710:40 pm
MDE
- SAN
1 stop16h 08m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$464
This oojo deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:43 am
SAN
- MDE
2 stops27h 27m
Multiple Airlines
Tue 5/2610:40 pm
MDE
- SAN
1 stop16h 21m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$465
Last-minute flights from San Diego to MedellínDiscover last-minute flight deals from San Diego to Medellín. Data last updated February 12, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Medellín. Data last updated February 12, 2026 and is based on user searches.
This Orbitz deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/211:00 pm
SAN
- MDE
1 stop29h 40m
Multiple Airlines
Tue 3/104:20 am
MDE
- SAN
2 stops17h 38m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$464
This Avianca deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/37:50 pm
SAN
- MDE
2 stops14h 05m
Multiple Airlines
Sun 3/86:25 am
MDE
- SAN
2 stops14h 40m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$408
This oojo deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/87:35 am
SAN
- MDE
1 stop26h 15m
Multiple Airlines
Sat 3/141:00 pm
MDE
- SAN
1 stop24h 53m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$444
This Orbitz deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/89:10 pm
SAN
- MDE
2 stops20h 00m
Multiple Airlines
Sun 3/152:10 pm
MDE
- SAN
2 stops21h 23m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$453
This Avianca deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/99:10 pm
SAN
- MDE
1 stop12h 40m
Multiple Airlines
Mon 3/164:45 am
MDE
- SAN
2 stops16h 20m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$392
This oojo deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/171:00 pm
SAN
- MDE
1 stop30h 40m
Multiple Airlines
Tue 3/318:00 pm
MDE
- SAN
1 stop18h 52m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$451
This oojo deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/243:48 pm
SAN
- MDE
1 stop27h 52m
Multiple Airlines
Fri 4/101:00 pm
MDE
- SAN
1 stop24h 46m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$460
This Trip.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/289:58 pm
SAN
- MDE
1 stop33h 12m
Multiple Airlines
Sat 4/48:00 pm
MDE
- SAN
1 stop18h 52m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$390
One-way flights from San Diego to MedellínSearch for one-way flight options from San Diego to Medellín. Find affordable one-way fares based on user searches. Data last updated February 12, 2026.
Search for one-way flight options from San Diego to Medellín. Find affordable one-way fares based on user searches. Data last updated February 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/712:00 pm
SAN
- MDE
3 stops34h 21m
Multiple Airlines
Deal found 2/8![Multiple Airlines logo]()
$153
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/76:25 am
SAN
- MDE
2 stops27h 30m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$166
This Avianca deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/159:05 pm
SAN
- MDE
1 stop12h 45m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/239:50 am
SAN
- MDE
3 stops25h 23m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$185
This Justfly.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/283:35 pm
SAN
- MDE
1 stop17h 15m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$194
This eDestinos deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/209:58 pm
SAN
- MDE
2 stops31h 29m
Multiple Airlines
Deal found 2/8![Multiple Airlines logo]()
$200
This Trip.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/211:00 pm
SAN
- MDE
1 stop29h 40m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$206
Find flight deals from San Diego to Medellín
Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 12, 2026.
Round-trip from | $382 (flugladen.de) |
|---|---|
One-way from | $153 (Kiwi.com) |
Popular in | March |
Cheapest in | October |
Average price | $520 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
Use the filters below to find and compare flights from San Diego to Medellín that are best for you.
Fly from
San Diego
Fly to
Medellín
Route
Depart
Return
Price
San DiegoMedellín
SAN - MDE
SANMDE
San Diego
Sat 3/28
9:58 pm-9:10 am
1 stop33h 12m
Medellín Jose Maria Cordova Intl
Sat 4/4
8:00 pm-12:52 pm
1 stop18h 52m
$390
San DiegoMedellín
SAN - MDE
SANMDE
San Diego
Mon 3/9
9:10 pm-11:50 am
1 stop12h 40m
Medellín Jose Maria Cordova Intl
Mon 3/16
4:45 am-7:05 pm
2 stops16h 20m
$392
San DiegoMedellín
SAN - MDE
SANMDE
San Diego
Sat 3/28
9:58 pm-9:10 am
1 stop33h 12m
Medellín Jose Maria Cordova Intl
Sun 4/12
1:00 pm-11:46 am
1 stop24h 46m
$444
San DiegoMedellín
SAN - MDE
SANMDE
San Diego
Tue 3/24
3:48 pm-9:40 pm
1 stop27h 52m
Medellín Jose Maria Cordova Intl
Fri 4/10
1:00 pm-11:46 am
1 stop24h 46m
$460
San DiegoMedellín
SAN - MDE
SANMDE
San Diego
Sun 3/29
3:48 pm-9:25 pm
1 stop27h 37m
Medellín Jose Maria Cordova Intl
Sun 4/12
1:00 pm-11:46 am
1 stop24h 46m
$460
San DiegoMedellín
SAN - MDE
SANMDE
San Diego
Tue 3/17
9:05 pm-5:50 pm
2 stops18h 45m
Medellín Jose Maria Cordova Intl
Tue 3/31
8:00 pm-12:52 pm
1 stop18h 52m
$461
San DiegoMedellín
SAN - MDE
SANMDE
San Diego
Sat 8/8
7:45 pm-1:10 pm
2 stops15h 25m
Medellín Jose Maria Cordova Intl
Wed 8/19
6:35 am-8:20 pm
1 stop15h 45m
$463
San DiegoMedellín
SAN - MDE
SANMDE
San Diego
Wed 5/6
11:05 am-1:10 pm
2 stops24h 05m
Medellín Jose Maria Cordova Intl
Thu 5/7
10:40 pm-12:48 pm
1 stop16h 08m
$464
San DiegoMedellín
SAN - MDE
SANMDE
San Diego
Thu 5/21
7:43 am-1:10 pm
2 stops27h 27m
Medellín Jose Maria Cordova Intl
Tue 5/26
10:40 pm-1:01 pm
1 stop16h 21m
$465
San DiegoMedellín
SAN - MDE
SANMDE
San Diego
Mon 3/2
10:30 am-10:05 pm
1 stop8h 35m
Medellín Jose Maria Cordova Intl
Wed 3/4
10:45 am-6:33 pm
1 stop10h 48m
$477
Showing 1-10 of 19 results
Best time to book a flight from San Diego to Medellín
Have a flexible travel schedule? Discover the best time to fly to Medellín from San Diego with our price prediction graph.
SAN-CO1
SAN-MDE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Medellín
SAN-CO1
SAN-MDE
How far ahead should I book a flight from San Diego to Medellín?
Use this chart to determine the optimal time to book a round-trip flight from San Diego to Medellín. Price data was last updated on February 6, 2026.
The best time to book flights from San Diego to Medellín is 64 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from San Diego to Medellín?
Currently, August is the cheapest month in which you can book a flight from San Diego to Medellín (average of $201). Flying from San Diego to Medellín in April is currently the most expensive (average of $522). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Diego to Medellín?
Reviews of airlines servicing Medellín
Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated February 12, 2026.
Read reviews from past customers who have flown Copa Airlines, United Airlines, and American Airlines from San Diego to Medellín. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.8
Comfort
7.4
Entertainment
6.8
Food
6.8
Crew
8.1
Overall
7.5
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Boarding
7.8
Comfort
7.4
Entertainment
6.8
Food
6.8
Crew
8.1
Overall
7.5
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Boarding
7.8
Comfort
7.4
Entertainment
6.8
Food
6.8
Crew
8.1
Overall
7.5
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Boarding
7.8
Comfort
7.4
Entertainment
6.8
Food
6.8
Crew
8.1
Overall
7.5
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Related info for your journey
Find useful and relevant information for your journey from San Diego to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for San Diego to Medellín
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Complete your trip
Complete your trip to Medellín by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Diego to Medellín by cabin class
Find flights from San Diego to Medellín, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Diego and Medellín flights
Browse other San Diego and Medellín flight options. Last updated on February 12, 2026.
Other flights from San Diego
Browse through other flights departing from San Diego. Flights are based on user searches made on Cheapflights and were last updated on February 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from San Diego to Medellín
Discover the top 3 airlines that operate flights from San Diego to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$333 | Average$440 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$452 | Average$693 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$452 | Average$597 | FlexibilityNo cancel fee | On-time69% |