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$161+ Cheap flights from Mexico City (MEX) to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/21. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — MDE
Dec 20 — Dec 271
Sat 12/20
Sat 12/27
1 adult, Economy
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Cheapflights Tip: The best prices from Mexico City Benito Juarez to Medellín are usually found in June or May, booked 77 days in advance, depart on a Tuesday or Monday and return on a Thursday

Find flight deals from Mexico City to Medellín

Cheapest flights from Mexico City to Medellín
Explore the most affordable flight options available from Mexico City to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 20, 2025.

This Avianca deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/34:00 amMEX - MDE
1 stop7h 55mAvianca
Sun 12/77:55 pmMDE - MEX
1 stop8h 05mAvianca
Deal found 11/19$340
This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/301:20 amMEX - MDE
1 stop5h 58mCopa Airlines
Thu 1/296:20 pmMDE - MEX
1 stop7h 40mCopa Airlines
Deal found 11/18$341
This Aeromexico deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:00 pmMEX - MDE
Nonstop4h 30mAeromexico
Wed 1/2812:45 amMDE - MEX
Nonstop4h 20mAeromexico
Deal found 11/18$346
This Avianca deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:00 amMEX - MDE
Nonstop4h 20mAvianca
Sat 1/3111:40 amMDE - MEX
1 stop7h 30mAvianca
Deal found 11/18$348
This Avianca deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/74:00 amMEX - MDE
1 stop7h 55mAvianca
Sun 12/1410:35 pmMDE - MEX
Nonstop4h 20mAvianca
Deal found 11/18$368
This Copa Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/301:20 amMEX - MDE
1 stop8h 36mCopa Airlines
Sat 1/319:17 amMDE - MEX
1 stop11h 03mCopa Airlines
Deal found 11/18$375

Cheap flight deals from Mexico City to Medellín

Discover tips and strategies to find the most affordable flight options for your journey from Mexico City (MEX) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 20, 2025.

Round-trip from

$275
(Avianca)

One-way from

$161
(Travelocity)

Popular in

December

Cheapest in

June

Average price

$358
From Mexico City Benito Juarez to Medellín
Search Deals
One-way flight from Mexico City Benito Juarez to Medellín
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Highest demand for flights based on searches. 9% potential increase in price ($34 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico City to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
Use the filters below to find and compare flights from Mexico City to Medellín that are best for you.

Fly from

Mexico City

Fly to

Medellín

Route

Depart

Return

Price

Mexico CityMedellín

MEX - MDE

MEXMDE

Mexico City Benito Juarez

Tue 2/3

3:30 pm-8:18 am

1 stop15h 48m

Medellín Jose Maria Cordova Intl

Tue 2/10

6:20 pm-1:00 am

1 stop7h 40m

$378

Mexico CityMedellín

MEX - MDE

MEXMDE

Mexico City Benito Juarez

Sun 2/8

5:55 am-2:15 pm

1 stop7h 20m

Medellín Jose Maria Cordova Intl

Sun 2/15

10:46 am-7:20 pm

1 stop9h 34m

$389

Mexico CityMedellín

MEX - MDE

MEXMDE

Mexico City Benito Juarez

Sat 2/7

1:20 am-9:51 am

1 stop7h 31m

Medellín Jose Maria Cordova Intl

Mon 2/16

10:46 am-7:20 pm

1 stop9h 34m

$389

Mexico CityMedellín

MEX - MDE

MEXMDE

Mexico City Benito Juarez

Sat 1/17

2:00 am-9:51 am

1 stop6h 51m

Medellín Jose Maria Cordova Intl

Sat 1/24

10:46 am-10:05 pm

1 stop12h 19m

$416

Mexico CityMedellín

MEX - MDE

MEXMDE

Mexico City Benito Juarez

Thu 12/11

3:30 pm-8:18 am

1 stop15h 48m

Medellín Jose Maria Cordova Intl

Tue 12/16

9:17 am-10:05 pm

1 stop13h 48m

$436

Mexico CityMedellín

MEX - MDE

MEXMDE

Mexico City Benito Juarez

Wed 12/10

2:00 am-2:15 pm

1 stop11h 15m

Medellín Jose Maria Cordova Intl

Mon 12/15

8:37 am-7:20 pm

1 stop11h 43m

$436

Mexico CityMedellín

MEX - MDE

MEXMDE

Mexico City Benito Juarez

Sun 2/1

1:20 am-9:51 am

1 stop7h 31m

Medellín Jose Maria Cordova Intl

Tue 2/17

10:46 am-7:20 pm

1 stop9h 34m

$448

Mexico CityMedellín

MEX - MDE

MEXMDE

Mexico City Benito Juarez

Tue 1/20

5:00 am-10:20 am

Nonstop4h 20m

$175

Mexico CityMedellín

MEX - MDE

MEXMDE

Mexico City Benito Juarez

Mon 1/5

5:00 am-10:20 am

Nonstop4h 20m

$175

Mexico CityMedellín

MEX - MDE

MEXMDE

Mexico City Benito Juarez

Sun 12/7

4:00 am-12:55 pm

1 stop7h 55m

$177

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/18

Showing 1-10 of 16 results
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Best time to book a flight from Mexico City to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from Mexico City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City to Medellín

How far ahead should I book a flight from Mexico City to Medellín?

Use this chart to determine the optimal time to book a round-trip flight from Mexico City to Medellín. Price data was last updated on November 14, 2025.

The best time to book flights from Mexico City to Medellín is 77 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Mexico City to Medellín?

Currently, March is the cheapest month in which you can book a flight from Mexico City to Medellín (average of $118). Flying from Mexico City to Medellín in December is currently the most expensive (average of $262). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MEX to MDE?

Find hourly flight availability from Mexico City to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 20, 2025.

One of the essential ways to save on airfare from Mexico City to Medellín is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight at noon could potentially save you up to 35% on airfare.

What is the cheapest day to fly from Mexico City to Medellín?

Use this chart to determine the cheapest time to fly round-trip from Mexico City to Medellín. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Mexico City to Medellín flight should consider departing on Friday at noon when fares are most often at their lowest. Wednesday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

How often are flights from Mexico City to Medellín delayed?

About 11% of weekly flights between Mexico City and Medellín have experienced delays in the past year, with the average delay time being 108 minutes.

What is the most punctual flight time for Mexico City to Medellín flights?

Historically, flights departing in the early afternoon are less likely to be delayed, whereas flights leaving in the evening tend to experience delays more often.

What day of the week experiences the fewest flight delays on this route?

Friday tends to have the lowest number of delays on this route, whereas Saturday has historically faced a higher average of delays compared to other days of the week.

Which airline has the best punctuality record on Mexico City to Medellín flights?

Over the last year, Avianca have had the lowest number of delays on this route, with just 10% of flights being delayed.

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated November 20, 2025.
See what other customers who have flown with Copa Airlines, Aeromexico, and Avianca from Mexico City to Medellín have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,566 reviews

Entertainment

6.8

Food

6.9

Overall

7.6

Crew

8.1

Comfort

7.4

Boarding

7.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
Copa Airlines
7.6
Good
1,566 reviews
Copa Airlines
7.6
Good
1,566 reviews

Entertainment

6.8

Food

6.9

Overall

7.6

Crew

8.1

Comfort

7.4

Boarding

7.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
Aeromexico
7.4
Good
1,660 reviews
Copa Airlines
7.6
Good
1,566 reviews

Entertainment

6.8

Food

6.9

Overall

7.6

Crew

8.1

Comfort

7.4

Boarding

7.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
Avianca
6.6
Okay
2,476 reviews
Copa Airlines
7.6
Good
1,566 reviews

Entertainment

6.8

Food

6.9

Overall

7.6

Crew

8.1

Comfort

7.4

Boarding

7.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring

Related info for your journey

Find useful and relevant information for your journey from Mexico City to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Mexico City to Medellín?

    Mexico City Benito Juarez (MEX), located 5.5 mi from the city center, is the airport you fly out of when you book flights from Mexico City to Medellín. 3 airlines have flights from Benito Juarez to Medellín on a regular basis. Booking flights from Mexico City Benito Juarez to Medellín should not be difficult; the airport handles an average of 2 outbound flights to Medellín per day.

  • How long is the flight from Mexico City to Medellín?

    Departing from Mexico City to Medellín will take you 15h 48m. The distance between Mexico City and Medellín is about 1833 mi.

  • What are the cheapest airlines flying from Mexico City to Medellín round-trip?

    Cheapflights users have booked flights from Mexico City to Medellín round-trip from $274. Other airlines that can offer you cheap pricing are Copa Airlines, from $275, and Avianca, from $279. Aeromexico is 20% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the most reliable airlines from Mexico City to Medellín?

    The top 3 most reliable airlines when flying from Mexico City to Medellín are Avianca (92%), Aeromexico (92%) and WestJet (92%).

  • What are the cheapest flights from Mexico City to Medellín?

    Looking at all options, your cheapest flight can be booked for $160. While the most popular route (Mexico City Benito Juarez - Medellín Jose Maria Cordova Intl) can be booked for $287 on average, our data indicates $383 when flying from Mexico City to Medellín.

  • Can I find deals for flights from Mexico City to Medellín that include hotel bookings?

    Yes. In addition to deals on Mexico City to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Medellín.

  • Can I find deals for business class flights from Mexico City to Medellín?

    Yes. Cheapflights offers flight deals from Mexico City to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City to Medellín?

    Currently, March is the cheapest month in which you can book a flight from Mexico City to Medellín (average of $118). Flying from Mexico City to Medellín in December is currently the most expensive (average of $262). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Mexico City to Medellín

Discover the top 3 airlines that operate flights from Mexico City to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
AeromexicoCheapest$274Average$443FlexibilityNo cancel feeOn-timeN/A
Copa AirlinesCheapest$275Average$367FlexibilityNo cancel feeOn-time70%
AviancaCheapest$279Average$365FlexibilityNo cancel feeOn-time71%

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