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$168+ Cheap flights from Mexico City (MEX) to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/22. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — MDE
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheapflights Tip: The best prices from Mexico City Benito Juarez to Medellín are usually found in June or February, booked 82 days in advance, depart on a Friday or Wednesday and return on a Thursday

Cheap flight deals from Mexico City to Medellín

Discover tips and strategies to find the most affordable flight options for your journey from Mexico City (MEX) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$294
(Avianca)

One-way from

$168
(Kiwi.com)

Popular in

December

Cheapest in

June

Average price

$342
From Mexico City Benito Juarez to Medellín
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One-way flight from Mexico City Benito Juarez to Medellín
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Highest demand for flights based on searches. 8% potential increase in price ($34 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Mexico City to Medellín

Cheapest flights from Mexico City to Medellín
Explore the most affordable flight options available from Mexico City to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Avianca deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/225:00 amMEX - MDE
Nonstop4h 20mAvianca
Tue 11/258:50 amMDE - MEX
2 stops10h 20mAvianca
Deal found 9/14$305
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/281:10 pmMEX - MDE
1 stop6h 06mCopa Airlines
Sat 11/84:30 pmMDE - MEX
1 stop6h 30mCopa Airlines
Deal found 9/13$309
This Avianca deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/45:00 amMEX - MDE
Nonstop4h 20mAvianca
Sun 12/74:15 pmMDE - MEX
1 stop7h 40mAvianca
Deal found 9/14$315
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/192:00 amMEX - MDE
1 stop6h 10mCopa Airlines
Sat 9/274:30 pmMDE - MEX
1 stop8h 45mCopa Airlines
Deal found 9/15$320
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/112:40 amMEX - MDE
1 stop10h 15mMultiple Airlines
Sun 10/54:32 amMDE - MEX
2 stops11h 53mMultiple Airlines
Deal found 9/14$331
This Avianca deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:00 amMEX - MDE
Nonstop4h 20mAvianca
Sun 1/114:15 pmMDE - MEX
1 stop7h 40mAvianca
Deal found 9/14$332
This Avianca deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/15:00 amMEX - MDE
Nonstop4h 05mAvianca
Mon 10/68:52 pmMDE - MEX
1 stop7h 13mAvianca
Deal found 9/13$340

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico City to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Mexico City to Medellín that are best for you.

Fly from

Mexico City

Fly to

Medellín

Route

Depart

Return

Price

Mexico CityMedellín

MEX - MDE

MEXMDE

Mexico City Benito Juarez

Sat 2/7

3:30 pm-8:18 am

1 stop15h 48m

Medellín Jose Maria Cordova Intl

Wed 2/11

9:17 am-7:20 pm

1 stop11h 03m

$343

Mexico CityMedellín

MEX - MDE

MEXMDE

Mexico City Benito Juarez

Sat 2/28

2:00 am-2:15 pm

1 stop11h 15m

Medellín Jose Maria Cordova Intl

Mon 3/16

10:46 am-7:20 pm

1 stop9h 34m

$343

Mexico CityMedellín

MEX - MDE

MEXMDE

Mexico City Benito Juarez

Tue 11/18

2:00 am-9:51 am

1 stop6h 51m

Medellín Jose Maria Cordova Intl

Sun 11/23

9:17 am-1:00 am

1 stop16h 43m

$343

Mexico CityMedellín

MEX - MDE

MEXMDE

Mexico City Benito Juarez

Fri 10/3

3:30 pm-9:10 am

1 stop16h 40m

Medellín Jose Maria Cordova Intl

Sun 10/12

10:46 am-1:00 am

1 stop15h 14m

$343

Mexico CityMedellín

MEX - MDE

MEXMDE

Mexico City Benito Juarez

Fri 3/6

5:55 am-8:35 pm

1 stop13h 40m

Medellín Jose Maria Cordova Intl

Tue 3/17

10:46 am-7:20 pm

1 stop9h 34m

$343

Mexico CityMedellín

MEX - MDE

MEXMDE

Mexico City Benito Juarez

Mon 2/2

3:30 pm-8:18 am

1 stop15h 48m

Medellín Jose Maria Cordova Intl

Tue 2/17

10:46 am-12:15 am

1 stop14h 29m

$343

Mexico CityMedellín

MEX - MDE

MEXMDE

Mexico City Benito Juarez

Mon 2/9

1:20 am-8:18 am

1 stop5h 58m

Medellín Jose Maria Cordova Intl

Tue 2/24

10:46 am-7:20 pm

1 stop9h 34m

$343

Mexico CityMedellín

MEX - MDE

MEXMDE

Mexico City Benito Juarez

Tue 11/18

9:25 am-8:16 pm

1 stop9h 51m

Medellín Jose Maria Cordova Intl

Fri 11/28

10:46 am-7:20 pm

1 stop9h 34m

$343

Mexico CityMedellín

MEX - MDE

MEXMDE

Mexico City Benito Juarez

Thu 2/12

5:55 am-8:35 pm

1 stop13h 40m

Medellín Jose Maria Cordova Intl

Mon 2/16

8:37 am-12:15 am

1 stop16h 38m

$343

Mexico CityMedellín

MEX - MDE

MEXMDE

Mexico City Benito Juarez

Sat 2/28

3:30 pm-8:18 am

1 stop15h 48m

Medellín Jose Maria Cordova Intl

Sun 3/8

9:17 am-12:15 am

1 stop15h 58m

$343

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 21 results
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Best time to book a flight from Mexico City to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from Mexico City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City to Medellín

How far ahead should I book a flight from Mexico City to Medellín?

Use this chart to determine the optimal time to book a round-trip flight from Mexico City to Medellín. Price data was last updated on September 12, 2025.

The best time to book flights from Mexico City to Medellín is 82 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Mexico City to Medellín?

Currently, January is the cheapest month in which you can book a flight from Mexico City to Medellín (average of $378). Flying from Mexico City to Medellín in December is currently the most expensive (average of $625). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MEX to MDE?

Find hourly flight availability from Mexico City to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

One of the essential ways to save on airfare from Mexico City to Medellín is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight at noon could potentially save you up to 21% on airfare.

What is the cheapest day to fly from Mexico City to Medellín?

Use this chart to determine the cheapest time to fly round-trip from Mexico City to Medellín. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Mexico City to Medellín flight should consider departing on Thursday at noon when fares are most often at their lowest. Saturday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Mexico City to Medellín

Explore weekly flight availability from Mexico City to Medellín. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 16, 2025.

The most flights from MEX to CO1 are scheduled on a Tuesday (2 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (1 on average).

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated September 16, 2025.
See what other customers who have flown with Copa Airlines, Aeromexico, and Avianca from Mexico City to Medellín have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,531 reviews

Comfort

7.4

Entertainment

6.8

Crew

8.1

Overall

7.6

Boarding

7.8

Food

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
Copa Airlines
7.6
Good
1,531 reviews
Copa Airlines
7.6
Good
1,531 reviews

Comfort

7.4

Entertainment

6.8

Crew

8.1

Overall

7.6

Boarding

7.8

Food

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
Aeromexico
7.5
Good
1,696 reviews
Copa Airlines
7.6
Good
1,531 reviews

Comfort

7.4

Entertainment

6.8

Crew

8.1

Overall

7.6

Boarding

7.8

Food

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring
Avianca
6.7
Okay
2,435 reviews
Copa Airlines
7.6
Good
1,531 reviews

Comfort

7.4

Entertainment

6.8

Crew

8.1

Overall

7.6

Boarding

7.8

Food

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring

Related info for your journey

Find useful and relevant information for your journey from Mexico City to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Mexico City to Medellín?

    Mexico City Benito Juarez (MEX), located 5.5 mi from the city center, is the airport you fly out of when you book flights from Mexico City to Medellín. 3 airlines have flights from Benito Juarez to Medellín on a regular basis. Booking flights from Mexico City Benito Juarez to Medellín should not be difficult; the airport handles an average of 1 outbound flight to Medellín per day.

  • How long is the flight from Mexico City to Medellín?

    Departing from Mexico City to Medellín will take you 15h 48m. The distance between Mexico City and Medellín is about 1833 mi.

  • What are the cheapest airlines flying from Mexico City to Medellín round-trip?

    Cheapflights users have booked flights from Mexico City to Medellín round-trip from $279. Other airlines that can offer you cheap pricing are Avianca, from $280, and Aeromexico, from $308. Copa Airlines is 19% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest flights from Mexico City to Medellín?

    Looking at all options, your cheapest flight can be booked for $164. While the most popular route (Mexico City Benito Juarez - Medellín Jose Maria Cordova Intl) can be booked for $250 on average, our data indicates $351 when flying from Mexico City to Medellín.

  • Can I find deals for flights from Mexico City to Medellín that include hotel bookings?

    Yes. In addition to deals on Mexico City to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Medellín.

  • Can I find deals for business class flights from Mexico City to Medellín?

    Yes. Cheapflights offers flight deals from Mexico City to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City to Medellín?

    Currently, January is the cheapest month in which you can book a flight from Mexico City to Medellín (average of $378). Flying from Mexico City to Medellín in December is currently the most expensive (average of $625). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Mexico City to Medellín

Discover the top 3 airlines that operate flights from Mexico City to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$279Average$385FlexibilityNo cancel feeOn-time70%
AviancaCheapest$280Average$354FlexibilityNo cancel feeOn-time71%
AeromexicoCheapest$308Average$443FlexibilityNo cancel feeOn-timeN/A

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