$171+ Cheap flights from Irvine, CA to Medellín
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/20. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — MDE
Oct 16 — Oct 231
1 adult, Economy
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Find cheap flights from Irvine to Medellín with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Irvine to Medellín are usually found in May or January, booked 48 days in advance, depart on a Tuesday or Sunday and return on a Sunday
Cheap flight deals from Irvine to Medellín
Keep the following information in mind while searching for Irvine to Medellín flight deals. Data was last updated September 16, 2025.
Round-trip from | $397 (Priceline) |
|---|---|
One-way from | $171 (Cheapflightsfares) |
Popular in | December |
Cheapest in | May |
Average price | $510 |
Find flight deals from Irvine to Medellín
Cheapest flights from Irvine to MedellínExplore the most affordable flight options available from Irvine to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.
Explore the most affordable flight options available from Irvine to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.
This Priceline deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1412:57 amLAX - MDE
2 stops14h 07mMultiple Airlines
Thu 11/202:10 pmMDE - LAX
1 stop10h 05mMultiple Airlines
Deal found 9/16![Multiple Airlines logo]()
$397
This Copa Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1910:04 pmLAX - MDE
1 stop9h 06mCopa Airlines
Sat 9/2710:46 amMDE - LAX
1 stop14h 26mCopa Airlines
Deal found 9/16![Copa Airlines logo]()
$401
This KAYAK deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/46:07 pmLAX - MDE
2 stops20h 57mSpirit Airlines
Sat 11/86:59 pmMDE - LAX
1 stop29h 40mSpirit Airlines
Deal found 9/15![Spirit Airlines logo]()
$402
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/261:50 amLAX - MDE
1 stop10h 25mCopa Airlines
Mon 11/33:15 pmMDE - LAX
1 stop10h 19mCopa Airlines
Deal found 9/15![Copa Airlines logo]()
$404
This KAYAK deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1810:35 amLAX - MDE
2 stops11h 46mSpirit Airlines
Sun 10/261:16 amMDE - LAX
1 stop23h 39mSpirit Airlines
Deal found 9/16![Spirit Airlines logo]()
$405
This Mytrip deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2812:09 amLAX - MDE
2 stops22h 12mMultiple Airlines
Wed 11/57:18 amMDE - LAX
3 stops28h 50mMultiple Airlines
Deal found 9/13![Multiple Airlines logo]()
$406
This CheapOair deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/612:09 amLAX - MDE
2 stops22h 12mSpirit Airlines
Tue 10/142:22 pmMDE - LAX
2 stops19h 55mSpirit Airlines
Deal found 9/16![Spirit Airlines logo]()
$407
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/712:09 amLAX - MDE
2 stops22h 12mMultiple Airlines
Sat 10/111:59 pmMDE - LAX
1 stop20h 29mMultiple Airlines
Deal found 9/14![Multiple Airlines logo]()
$408
This KAYAK deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1011:15 amLAX - MDE
1 stop11h 06mSpirit Airlines
Thu 10/161:16 amMDE - LAX
1 stop23h 39mSpirit Airlines
Deal found 9/16![Spirit Airlines logo]()
$409
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/911:15 amLAX - MDE
1 stop11h 06mMultiple Airlines
Tue 10/141:59 pmMDE - LAX
1 stop20h 29mMultiple Airlines
Deal found 9/15![Multiple Airlines logo]()
$410
This CheapOair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/911:15 amLAX - MDE
1 stop11h 06mSpirit Airlines
Sun 10/121:16 amMDE - LAX
2 stops24h 32mSpirit Airlines
Deal found 9/14![Spirit Airlines logo]()
$411
This Expedia deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1712:09 amLAX - MDE
2 stops11h 02mSpirit Airlines
Fri 10/242:22 pmMDE - LAX
2 stops19h 55mSpirit Airlines
Deal found 9/14![Spirit Airlines logo]()
$412
Cheapflights Fare Finder
Customize your flight search to find flights from Irvine to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Irvine to Medellín that are best for you.
Fly from
Irvine
Fly to
Medellín
Route
Depart
Return
Price
Los AngelesMedellín
LAX - MDE
LAXMDE
Los Angeles
Sat 10/4
12:06 pm-10:51 pm
1 stop8h 45m
Medellín Jose Maria Cordova Intl
Sat 10/11
9:15 am-11:12 pm
1 stop15h 57m
$401
Los AngelesMedellín
LAX - MDE
LAXMDE
Los Angeles
Sat 10/4
12:06 pm-9:10 am
1 stop19h 04m
Medellín Jose Maria Cordova Intl
Tue 10/14
9:15 am-11:12 pm
1 stop15h 57m
$401
Los AngelesMedellín
LAX - MDE
LAXMDE
Los Angeles
Thu 10/9
11:15 am-12:21 am
1 stop11h 06m
Medellín Jose Maria Cordova Intl
Tue 10/14
1:59 pm-8:28 am
1 stop20h 29m
$410
Los AngelesMedellín
LAX - MDE
LAXMDE
Los Angeles
Tue 11/18
11:05 am-9:51 am
1 stop19h 46m
Medellín Jose Maria Cordova Intl
Sun 12/7
10:46 am-10:44 pm
1 stop14h 58m
$440
Los AngelesMedellín
LAX - MDE
LAXMDE
Los Angeles
Tue 11/4
10:35 pm-2:32 pm
1 stop12h 57m
Medellín Jose Maria Cordova Intl
Sat 11/8
2:10 pm-11:02 pm
1 stop11h 52m
$446
Los AngelesMedellín
LAX - MDE
LAXMDE
Los Angeles
Wed 11/5
12:52 am-2:15 pm
1 stop10h 23m
Medellín Jose Maria Cordova Intl
Tue 11/11
10:46 am-10:44 pm
1 stop14h 58m
$462
Los AngelesMedellín
LAX - MDE
LAXMDE
Los Angeles
Fri 11/28
9:04 pm-2:45 pm
1 stop14h 41m
Medellín Jose Maria Cordova Intl
Mon 12/8
10:46 am-10:34 pm
1 stop14h 48m
$490
Los AngelesMedellín
LAX - MDE
LAXMDE
Los Angeles
Sun 11/30
9:04 pm-2:45 pm
1 stop14h 41m
Medellín Jose Maria Cordova Intl
Tue 12/9
10:46 am-10:44 pm
1 stop14h 58m
$490
Los AngelesMedellín
LAX - MDE
LAXMDE
Los Angeles
Mon 11/24
9:04 pm-2:15 pm
1 stop14h 11m
Medellín Jose Maria Cordova Intl
Thu 11/27
10:46 am-10:44 pm
1 stop14h 58m
$490
Los AngelesMedellín
LAX - MDE
LAXMDE
Los Angeles
Thu 10/16
7:20 pm-9:10 pm
1 stop23h 50m
Medellín Jose Maria Cordova Intl
Sat 11/1
9:45 am-10:09 am
1 stop26h 24m
$493
Showing 1-10 of 28 results
Best time to book a flight from Irvine to Medellín
Have a flexible travel schedule? Discover the best time to fly to Medellín from Irvine with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Irvine to Medellín
How far ahead should I book a flight from Irvine to Medellín?
Use this chart to determine the optimal time to book a round-trip flight from Irvine to Medellín. Price data was last updated on September 12, 2025.
Booking 48 days in advance of your planned departure date is, on average, the best time to get cheap flights from Irvine to Medellín. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Irvine to Medellín?
Currently, January is the cheapest month in which you can book a flight from Irvine to Medellín (average of $378). Flying from Irvine to Medellín in December is currently the most expensive (average of $625). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from IR9 to MDE?
Find hourly flight availability from Irvine to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Irvine to Medellín as you normally would.
What is the cheapest day to fly from Irvine to Medellín?
Use this chart to determine the cheapest time to fly round-trip from Irvine to Medellín. Price data was last updated on October 20, 2024.
Travelers seeking maximum savings on their Irvine to Medellín flight should consider departing on Tuesday at noon when fares are most often at their lowest. Thursday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Medellín
Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated September 16, 2025.
Read through reviews of airlines operating flights from Irvine to Medellín, such as Copa Airlines, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.4
Food
6.8
Crew
8.1
Entertainment
6.8
Boarding
7.8
Overall
7.6
Reviews
1 / 20
10.0
ExcellentJuan Pablo,Sep 2025
MEX - PTY
Comfort
7.4
Food
6.8
Crew
8.1
Entertainment
6.8
Boarding
7.8
Overall
7.6
Reviews
1 / 20
10.0
ExcellentJuan Pablo,Sep 2025
MEX - PTY
Comfort
7.4
Food
6.8
Crew
8.1
Entertainment
6.8
Boarding
7.8
Overall
7.6
Reviews
1 / 20
10.0
ExcellentJuan Pablo,Sep 2025
MEX - PTY
Comfort
7.4
Food
6.8
Crew
8.1
Entertainment
6.8
Boarding
7.8
Overall
7.6
Reviews
1 / 20
10.0
ExcellentJuan Pablo,Sep 2025
MEX - PTY
Comfort
7.4
Food
6.8
Crew
8.1
Entertainment
6.8
Boarding
7.8
Overall
7.6
Reviews
1 / 20
10.0
ExcellentJuan Pablo,Sep 2025
MEX - PTY
Comfort
7.4
Food
6.8
Crew
8.1
Entertainment
6.8
Boarding
7.8
Overall
7.6
Reviews
1 / 20
10.0
ExcellentJuan Pablo,Sep 2025
MEX - PTY
Related info for your journey
Find useful and relevant information for your journey from Irvine to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Irvine to Medellín
See prices for flight routes from nearby airports that may be better suited for you.
Top 6 airlines flying from Irvine to Medellín
Discover the top 6 airlines that operate flights from Irvine to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$262 | Average$552 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$347 | Average$545 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$403 | Average$599 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$415 | Average$592 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$436 | Average$577 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$452 | Average$562 | FlexibilityNo cancel fee | On-time71% |