$152+ Cheap flights from Irvine, CA to Medellín
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/31. Fares are subject to change and may not be available on all flights or dates of travel.
Find cheap flights from Irvine to Medellín with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Irvine to Medellín are usually found in October or May, booked 38 days in advance, depart on a Tuesday or Sunday and return on a Sunday
Cheap flight deals from Irvine to Medellín
Cheapest flights from Irvine to MedellínExplore the most affordable flight options available from Irvine to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.
Explore the most affordable flight options available from Irvine to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.
This FlightHub deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Cheapflightsfares deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This FlightHub deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This oojo deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Find flight deals from Irvine to Medellín
Keep the following information in mind while searching for Irvine to Medellín flight deals. Data was last updated December 18, 2025.
Round-trip from | $336 (Cheapflightsfares) |
|---|---|
One-way from | $152 (Super.com) |
Popular in | December |
Cheapest in | October |
Average price | $807 |
Cheapflights Fare Finder
Use the filters below to find and compare flights from Irvine to Medellín that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
Los AngelesMedellín
LAX - MDE
LAXMDE
Los Angeles
Fri 1/30
11:59 pm-2:15 pm
1 stop11h 16m
Medellín Jose Maria Cordova Intl
Fri 2/6
3:15 pm-6:02 pm
2 stops29h 47m
Los AngelesMedellín
LAX - MDE
LAXMDE
Los Angeles
Tue 1/27
10:25 pm-12:55 pm
1 stop11h 30m
Medellín Jose Maria Cordova Intl
Wed 2/4
2:10 pm-10:00 pm
1 stop10h 50m
Los AngelesMedellín
LAX - MDE
LAXMDE
Los Angeles
Wed 3/4
11:55 pm-5:05 pm
2 stops14h 10m
Medellín Jose Maria Cordova Intl
Sun 3/8
2:10 pm-10:15 pm
1 stop10h 05m
Los AngelesMedellín
LAX - MDE
LAXMDE
Los Angeles
Fri 3/6
12:25 pm-6:05 am
3 stops14h 40m
Medellín Jose Maria Cordova Intl
Sat 3/14
2:10 pm-10:15 pm
1 stop10h 05m
Los AngelesMedellín
LAX - MDE
LAXMDE
Los Angeles
Sun 2/1
11:55 pm-12:55 pm
1 stop10h 00m
Medellín Jose Maria Cordova Intl
Sat 2/7
2:10 pm-9:15 pm
1 stop10h 05m
Los AngelesMedellín
LAX - MDE
LAXMDE
Los Angeles
Sun 1/18
7:07 pm-2:15 pm
2 stops16h 08m
Medellín Jose Maria Cordova Intl
Fri 1/23
3:15 pm-5:39 pm
2 stops29h 24m
Los AngelesMedellín
LAX - MDE
LAXMDE
Los Angeles
Wed 1/28
11:55 pm-12:55 pm
1 stop10h 00m
Medellín Jose Maria Cordova Intl
Tue 2/3
2:10 pm-10:00 pm
1 stop10h 50m
Los AngelesMedellín
LAX - MDE
LAXMDE
Los Angeles
Thu 1/15
7:07 pm-2:15 pm
2 stops16h 08m
Medellín Jose Maria Cordova Intl
Mon 1/19
3:15 pm-6:02 pm
2 stops29h 47m
Los AngelesMedellín
LAX - MDE
LAXMDE
Los Angeles
Thu 1/29
11:59 pm-9:40 pm
1 stop18h 41m
Medellín Jose Maria Cordova Intl
Mon 2/2
1:00 pm-10:56 pm
1 stop12h 56m
Los AngelesMedellín
LAX - EOH
LAXEOH
Los Angeles
Thu 1/29
10:25 pm-4:40 pm
2 stops15h 15m
Medellín Enrique Olaya
Sun 2/1
4:20 pm-12:30 pm
2 stops23h 10m
Best time to book a flight from Irvine to Medellín
Have a flexible travel schedule? Discover the best time to fly to Medellín from Irvine with our price prediction graph.
Cheapflights Insights
Everything you need to know about your flight from Irvine to Medellín
How far ahead should I book a flight from Irvine to Medellín?
Use this chart to determine the optimal time to book a round-trip flight from Irvine to Medellín. Price data was last updated on December 12, 2025.
Booking 38 days in advance of your planned departure date is, on average, the best time to get cheap flights from Irvine to Medellín. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Irvine to Medellín?
Currently, November is the cheapest month in which you can book a flight from Irvine to Medellín (average of $231). Flying from Irvine to Medellín in July is currently the most expensive (average of $448). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from IR9 to MDE?
Find hourly flight availability from Irvine to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.
It’s typically best to fly out from Irvine to Medellín in the afternoon. Doing so could potentially save you 7% on the flight price compared to flying in the evening, which is usually more expensive.
What is the cheapest day to fly from Irvine to Medellín?
Use this chart to determine the cheapest time to fly round-trip from Irvine to Medellín. Price data was last updated on December 16, 2024.
Travelers seeking maximum savings on their Irvine to Medellín flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Saturday mornings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Medellín
Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated December 18, 2025.
Read through reviews of airlines operating flights from Irvine to Medellín, such as Copa Airlines, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
Entertainment
Comfort
Crew
Overall
Boarding
Reviews
Juan Pablo,Sep 2025
MEX - PTY
Food
Entertainment
Comfort
Crew
Overall
Boarding
Reviews
Juan Pablo,Sep 2025
MEX - PTY
Food
Entertainment
Comfort
Crew
Overall
Boarding
Reviews
Juan Pablo,Sep 2025
MEX - PTY
Food
Entertainment
Comfort
Crew
Overall
Boarding
Reviews
Juan Pablo,Sep 2025
MEX - PTY
Food
Entertainment
Comfort
Crew
Overall
Boarding
Reviews
Juan Pablo,Sep 2025
MEX - PTY
Food
Entertainment
Comfort
Crew
Overall
Boarding
Reviews
Juan Pablo,Sep 2025
MEX - PTY
Related info for your journey
Find useful and relevant information for your journey from Irvine to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Irvine to Medellín
See prices for flight routes from nearby airports that may be better suited for you.
Top 6 airlines flying from Irvine to Medellín
Discover the top 6 airlines that operate flights from Irvine to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$152 | Average$643 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$348 | Average$572 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$380 | Average$589 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$397 | Average$549 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$436 | Average$470 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$452 | Average$561 | FlexibilityNo cancel fee | On-time71% |