$377+ Cheap flights from Missouri to Manchester (MAN)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/11. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MAN
Oct 17 — Oct 241
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Missouri to Manchester with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to Manchester
Cheapest
Best
Last-minute
One-way
Cheapest flights from Missouri to ManchesterExplore the most affordable flight options available from Missouri to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
Explore the most affordable flight options available from Missouri to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
This Expedia deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:00 pm -
1 stop15h 45m
Wed 11/412:40 pm -
1 stop15h 19m
Deal found 9/13![Virgin Atlantic logo]()
$713
This Iberia deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/171:20 pm -
2 stops16h 00m
Mon 11/232:15 pm -
2 stops25h 16m
Deal found 9/17![Multiple Airlines logo]()
$732
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/132:40 pm -
1 stop9h 50m
Wed 10/219:00 am -
2 stops43h 30m
Deal found 9/13![United Airlines logo]()
$737
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/282:25 pm -
1 stop13h 20m
Wed 11/42:55 pm -
2 stops24h 22m
Deal found 9/13![Delta logo]()
$741
This Finnair deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/912:58 pm -
2 stops16h 47m
Tue 11/1711:55 am -
2 stops18h 04m
Deal found 9/17![Multiple Airlines logo]()
$745
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:27 pm -
2 stops17h 53m
Wed 11/412:10 pm -
2 stops17h 23m
Deal found 9/13![American Airlines logo]()
$746
This Cheapflightsfares deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1411:22 am -
2 stops19h 58m
Tue 10/206:40 pm -
2 stops33h 20m
Deal found 9/16![SWISS logo]()
$747
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:00 am -
1 stop19h 50m
Wed 10/2110:40 am -
1 stop19h 14m
Deal found 9/13![Delta logo]()
$749
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/912:28 pm -
2 stops15h 37m
Tue 11/1712:40 pm -
1 stop17h 16m
Deal found 9/17![Delta logo]()
$756
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:45 pm -
2 stops32h 15m
Thu 11/1911:30 am -
2 stops39h 17m
Deal found 9/17![United Airlines logo]()
$756
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1310:22 am -
2 stops17h 28m
Wed 10/219:20 am -
2 stops17h 37m
Deal found 9/13![American Airlines logo]()
$758
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1412:00 pm -
1 stop14h 15m
Tue 10/201:00 pm -
1 stop14h 17m
Deal found 9/14![Delta logo]()
$771
Best flights from Missouri to ManchesterDiscover carefully curated flight deals from Missouri to Manchester that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
Discover carefully curated flight deals from Missouri to Manchester that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
This Iberia deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/171:20 pm -
2 stops16h 00m
Mon 11/232:15 pm -
2 stops25h 16m
Deal found 9/17![Multiple Airlines logo]()
$732
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/132:40 pm -
1 stop9h 50m
Wed 10/219:00 am -
2 stops43h 30m
Deal found 9/13![United Airlines logo]()
$737
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/282:25 pm -
1 stop13h 20m
Wed 11/42:55 pm -
2 stops24h 22m
Deal found 9/13![Delta logo]()
$741
This Virgin Atlantic deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/249:00 am -
1 stop17h 45m
Tue 4/271:00 pm -
1 stop13h 49m
Deal found 9/16![Virgin Atlantic logo]()
$748
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/221:55 pm -
2 stops13h 50m
Wed 10/289:20 am -
2 stops17h 37m
Deal found 9/13![American Airlines logo]()
$830
This Finnair deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/912:58 pm -
2 stops16h 47m
Tue 11/1711:55 am -
2 stops18h 04m
Deal found 9/17![Multiple Airlines logo]()
$745
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1412:00 pm -
1 stop14h 15m
Tue 10/201:00 pm -
1 stop14h 17m
Deal found 9/14![Delta logo]()
$771
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:00 am -
2 stops21h 00m
Wed 11/46:10 am -
2 stops19h 33m
Deal found 9/13![United Airlines logo]()
$794
This Virgin Atlantic deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2610:32 am -
1 stop18h 18m
Fri 12/42:55 pm -
1 stop15h 01m
Deal found 9/16![Virgin Atlantic logo]()
$807
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/204:05 pm -
1 stop10h 55m
Fri 1/226:10 am -
2 stops21h 37m
Deal found 9/17![United Airlines logo]()
$795
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/218:05 am -
1 stop17h 10m
Mon 11/22:55 pm -
2 stops28h 12m
Deal found 9/15![Delta logo]()
$823
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2612:10 pm -
2 stops15h 55m
Fri 12/42:55 pm -
1 stop15h 01m
Deal found 9/17![Delta logo]()
$828
Last-minute flights from Missouri to ManchesterDiscover last-minute flight deals from Missouri to Manchester. Data last updated September 17, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Manchester. Data last updated September 17, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:15 am -
2 stops18h 15m
Sun 10/119:00 am -
2 stops35h 17m
Deal found 9/12![United Airlines logo]()
$806
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/132:40 pm -
1 stop9h 50m
Wed 10/219:00 am -
2 stops43h 30m
Deal found 9/13![United Airlines logo]()
$737
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:00 am -
1 stop19h 50m
Wed 10/2110:40 am -
1 stop19h 14m
Deal found 9/13![Delta logo]()
$749
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1310:22 am -
2 stops17h 28m
Wed 10/219:20 am -
2 stops17h 37m
Deal found 9/13![American Airlines logo]()
$758
This Cheapflightsfares deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1411:22 am -
2 stops19h 58m
Tue 10/206:40 pm -
2 stops33h 20m
Deal found 9/16![SWISS logo]()
$747
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1412:00 pm -
1 stop14h 15m
Tue 10/201:00 pm -
1 stop14h 17m
Deal found 9/14![Delta logo]()
$771
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/141:09 pm -
2 stops14h 41m
Tue 10/206:05 am -
2 stops21h 16m
Deal found 9/15![United Airlines logo]()
$800
This Expedia deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:00 pm -
1 stop15h 45m
Wed 11/412:40 pm -
1 stop15h 19m
Deal found 9/13![Virgin Atlantic logo]()
$713
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/282:25 pm -
1 stop13h 20m
Wed 11/42:55 pm -
2 stops24h 22m
Deal found 9/13![Delta logo]()
$741
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:27 pm -
2 stops17h 53m
Wed 11/412:10 pm -
2 stops17h 23m
Deal found 9/13![American Airlines logo]()
$746
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:00 am -
2 stops21h 00m
Wed 11/46:10 am -
2 stops19h 33m
Deal found 9/13![United Airlines logo]()
$794
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:10 pm -
2 stops16h 20m
Thu 11/58:50 am -
2 stops17h 29m
Deal found 9/14![American Airlines logo]()
$796
One-way flights from Missouri to ManchesterSearch for one-way flight options from Missouri to Manchester. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
Search for one-way flight options from Missouri to Manchester. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
This Justfly.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1111:31 am -
2 stops20h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![British Airways logo]()
$377
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/117:20 am -
1 stop21h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Delta logo]()
$390
This Ovago deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/126:00 pm -
2 stops32h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![British Airways logo]()
$493
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/122:00 pm -
3 stops46h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Multiple Airlines logo]()
$540
This Mytrip deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/114:05 pm -
3 stops21h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Multiple Airlines logo]()
$603
This BusinessClass deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1112:49 pm -
2 stops19h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![British Airways logo]()
$1,129
This BusinessClass deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/94:30 pm -
2 stops36h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![British Airways logo]()
$1,188
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/117:02 am -
3 stops55h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Multiple Airlines logo]()
$1,447
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:05 am -
1 stop18h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Delta logo]()
$1,761
Find flight deals from Missouri to Manchester
Keep the following information in mind while searching for Missouri to Manchester flight deals. Data was last updated September 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $713 (Expedia) |
One-way from | $377 (Justfly.com) |
Popular in | October |
Cheapest in | June |
Average price | $1,111 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
Use the filters below to find and compare flights from Missouri to Manchester that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisManchester
STL Lambert-St Louis - MAN Manchester
STLMAN
Lambert-St Louis
Thu 3/11
11:31 am-2:15 pm
2 stops20h 44m
Manchester
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$377
St. LouisManchester
STL Lambert-St Louis - MAN Manchester
STLMAN
Lambert-St Louis
Thu 3/11
7:20 am-10:50 am
1 stop21h 30m
Manchester
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$390
St. LouisManchester
STL Lambert-St Louis - MAN Manchester
STLMAN
Lambert-St Louis
Fri 3/12
9:00 am-10:30 am
1 stop19h 30m
Manchester
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$390
St. LouisManchester
STL Lambert-St Louis - MAN Manchester
STLMAN
Lambert-St Louis
Fri 3/12
2:00 pm-6:45 pm
3 stops46h 45m
Manchester
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$540
St. LouisManchester
STL Lambert-St Louis - MAN Manchester
STLMAN
Lambert-St Louis
Thu 3/11
4:05 pm-7:05 pm
3 stops21h 00m
Manchester
Wed 12/31
12:00 am-5:00 pm
Nonstop0h 00m
$603
St. LouisManchester
STL Lambert-St Louis - MAN Manchester
STLMAN
Lambert-St Louis
Tue 11/17
1:20 pm-11:20 am
2 stops16h 00m
Manchester
Mon 11/23
2:15 pm-9:31 am
2 stops25h 16m
$732
St. LouisManchester
STL Lambert-St Louis - MAN Manchester
STLMAN
Lambert-St Louis
Tue 10/13
2:40 pm-6:30 am
1 stop9h 50m
Manchester
Wed 10/21
9:00 am-10:30 pm
2 stops43h 30m
$737
St. LouisManchester
STL Lambert-St Louis - MAN Manchester
STLMAN
Lambert-St Louis
Wed 10/28
2:25 pm-8:45 am
1 stop13h 20m
Manchester
Wed 11/4
2:55 pm-9:17 am
2 stops24h 22m
$741
St. LouisManchester
STL Lambert-St Louis - MAN Manchester
STLMAN
Lambert-St Louis
Mon 11/9
12:58 pm-11:45 am
2 stops16h 47m
Manchester
Tue 11/17
11:55 am-11:59 pm
2 stops18h 04m
$745
St. LouisManchester
STL Lambert-St Louis - MAN Manchester
STLMAN
Lambert-St Louis
Wed 2/24
9:00 am-8:45 am
1 stop17h 45m
Manchester
Tue 4/27
1:00 pm-8:49 pm
1 stop13h 49m
$748
Showing 1-10 of 21 resultsSorted by cheapest first
Best time to book a flight from Missouri to Manchester
Have a flexible travel schedule? Discover the best time to fly to Manchester from Missouri with our price prediction graph.
STL-MAN
MCI-MAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Manchester
USMO-MAN
STL-MAN
MCI-MAN
What is the cheapest month to book a flight from Missouri to Manchester?
Currently, January is the cheapest month in which you can book a flight from Missouri to Manchester (average of $623). Flying from Missouri to Manchester in October is currently the most expensive (average of $1,382). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Missouri to Manchester?
Airfare is below average for this route at the moment.
Missouri to Manchester flights typically cost between $1,100 and $1,368 in October.The cheapest round-trip price found within the last 5 days was $713 on Virgin Atlantic (Oct 28-Nov 4).
Related info for your journey
Find useful and relevant information for your journey from Missouri to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Manchester?
Book flights to Manchester if you plan to visit one of these locationsBolton
Rochdale
Huddersfield
Southport
Stockport
Salford
Bromborough
Llandudno
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Manchester flight routes
Other flight options
Popular flights
Top destinations
Alternative routes for Missouri to Manchester
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Manchester by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Manchester by cabin class
Find flights from Missouri to Manchester, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Manchester
Explore flights to Manchester departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 17, 2026.
Missouri and Manchester flights
Browse other Missouri and Manchester flight options. Last updated on September 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Missouri to Manchester flights
Consider these flights traveling from Missouri to Manchester.
Top 5 airlines flying from Missouri to Manchester
Discover the top 5 airlines that operate flights from Missouri to Manchester. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$324 | Average$1,211 | FlexibilityNo cancel fee | On-time72% | |
| Cheapest$590 | Average$899 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$607 | Average$1,146 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$820 | Average$1,100 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$1,297 | Average$1,321 | FlexibilityNo cancel fee | On-time71% |