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$572+ Cheap flights from Santa Cruz de la Sierra (VVI) to Madrid, Spain (MAD)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/12. Fares are subject to change and may not be available on all flights or dates of travel.
VVI — MAD
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheapflights Tip: The best prices from Santa Cruz de la Sierra Viru Viru Intl to Madrid Barajas are usually found in December or April, booked 87 days in advance, depart on a Tuesday or Wednesday and return on a Friday

Cheap flight deals from Santa Cruz de la Sierra to Madrid

Discover tips and strategies to find the most affordable flight options for your journey from Santa Cruz de la Sierra (VVI) to Madrid (MAD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2025.

Round-trip from

$925
(Booking.com)

One-way from

$572
(Kiwi.com)

Popular in

January

Cheapest in

December

Average price

$1,259
From Santa Cruz de la Sierra Viru Viru Intl to Madrid Barajas
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One-way flight from Santa Cruz de la Sierra Viru Viru Intl to Madrid Barajas
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Highest demand for flights based on searches. 1% potential increase in price ($12 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($30 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Santa Cruz de la Sierra to Madrid

Cheapest flights from Santa Cruz de la Sierra to Madrid
Explore the most affordable flight options available from Santa Cruz de la Sierra to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Booking.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2112:20 pmVVI - MAD
Nonstop10h 50mAir Europa
Wed 11/1211:35 pmMAD - VVI
Nonstop11h 20mAir Europa
Deal found 9/15$925
This FlightHub deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/41:30 pmVVI - MAD
Nonstop10h 40mAir Europa
Fri 11/213:05 amMAD - VVI
Nonstop11h 20mAir Europa
Deal found 9/14$943
This CheapOair deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/25:25 amVVI - MAD
1 stop30h 00mLATAM Airlines
Wed 1/2812:40 amMAD - VVI
1 stop32h 55mLATAM Airlines
Deal found 9/15$967
This Iberia deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/216:50 pmVVI - MAD
Nonstop10h 50mIberia
Wed 11/122:40 pmMAD - VVI
Nonstop10h 00mIberia
Deal found 9/15$990
This Avianca deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/192:50 amVVI - MAD
1 stop22h 50mAvianca
Mon 11/36:35 amMAD - VVI
1 stop25h 00mAvianca
Deal found 9/15$1,002
This CheapOair deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/131:30 pmVVI - MAD
Nonstop10h 40mMultiple Airlines
Tue 11/2510:50 amMAD - VVI
1 stop20h 45mMultiple Airlines
Deal found 9/15$1,053
This CheapOair deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/135:25 amVVI - MAD
1 stop30h 00mLATAM Airlines
Mon 11/2412:40 amMAD - VVI
1 stop32h 55mLATAM Airlines
Deal found 9/15$1,065
This Avianca deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/92:50 amVVI - MAD
1 stop14h 40mAvianca
Fri 10/101:30 amMAD - VVI
1 stop30h 20mAvianca
Deal found 9/15$1,090
This CheapOair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/45:25 amVVI - MAD
1 stop30h 00mLATAM Airlines
Fri 11/2112:40 amMAD - VVI
1 stop32h 55mLATAM Airlines
Deal found 9/14$1,103
This Gotogate deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/11:10 pmVVI - MAD
2 stops29h 25mMultiple Airlines
Wed 12/106:35 pmMAD - VVI
2 stops39h 15mMultiple Airlines
Deal found 9/15$1,108

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Cruz de la Sierra to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Santa Cruz de la Sierra to Madrid that are best for you.

Fly from

Santa Cruz de la Sierra

Fly to

Madrid

Route

Depart

Return

Price

Santa Cruz de la SierraMadrid

VVI - MAD

VVIMAD

Santa Cruz de la Sierra Viru Viru Intl

Tue 11/4

1:30 pm-5:10 am

Nonstop10h 40m

Madrid Barajas

Fri 11/21

3:05 am-9:25 am

Nonstop11h 20m

$943

Santa Cruz de la SierraMadrid

VVI - MAD

VVIMAD

Santa Cruz de la Sierra Viru Viru Intl

Mon 11/17

9:15 pm-1:55 pm

Nonstop11h 40m

Madrid Barajas

Sun 11/23

9:00 pm-2:30 am

Nonstop10h 30m

$990

Santa Cruz de la SierraMadrid

VVI - MAD

VVIMAD

Santa Cruz de la Sierra Viru Viru Intl

Thu 12/25

1:30 pm-5:10 am

Nonstop10h 40m

Madrid Barajas

Sat 1/10

6:35 am-2:35 am

1 stop25h 00m

$1,053

Santa Cruz de la SierraMadrid

VVI - MAD

VVIMAD

Santa Cruz de la Sierra Viru Viru Intl

Tue 3/10

9:05 am-4:10 pm

2 stops26h 05m

Madrid Barajas

Tue 3/24

5:05 pm-5:00 pm

2 stops28h 55m

$1,104

Santa Cruz de la SierraMadrid

VVI - MAD

VVIMAD

Santa Cruz de la Sierra Viru Viru Intl

Tue 12/2

9:05 am-4:10 pm

2 stops26h 05m

Madrid Barajas

Thu 1/29

6:00 am-2:35 am

2 stops25h 35m

$1,112

Santa Cruz de la SierraMadrid

VVI - MAD

VVIMAD

Santa Cruz de la Sierra Viru Viru Intl

Mon 11/17

9:05 am-11:35 pm

2 stops33h 30m

Madrid Barajas

Sun 11/23

7:25 am-4:50 am

2 stops26h 25m

$1,115

Santa Cruz de la SierraMadrid

VVI - MAD

VVIMAD

Santa Cruz de la Sierra Viru Viru Intl

Mon 11/17

5:25 am-4:25 pm

1 stop30h 00m

Madrid Barajas

Sun 11/23

1:10 pm-4:35 am

1 stop20h 25m

$1,234

Santa Cruz de la SierraMadrid

VVI - MAD

VVIMAD

Santa Cruz de la Sierra Viru Viru Intl

Thu 10/16

5:20 am-5:20 pm

1 stop30h 00m

Madrid Barajas

Tue 10/21

1:00 pm-4:35 am

1 stop21h 35m

$1,234

Santa Cruz de la SierraMadrid

VVI - MAD

VVIMAD

Santa Cruz de la Sierra Viru Viru Intl

Mon 3/2

5:25 am-4:25 pm

1 stop30h 00m

Madrid Barajas

Sat 3/21

12:40 am-4:35 am

1 stop32h 55m

$1,265

Santa Cruz de la SierraMadrid

VVI - MAD

VVIMAD

Santa Cruz de la Sierra Viru Viru Intl

Mon 12/1

3:40 am-11:20 pm

1 stop14h 40m

Madrid Barajas

Wed 1/28

1:20 am-2:35 am

1 stop30h 15m

$1,268

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 20 results
1
2

Best time to book a flight from Santa Cruz de la Sierra to Madrid

Have a flexible travel schedule? Discover the best time to fly to Madrid from Santa Cruz de la Sierra with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Cruz de la Sierra to Madrid

How far ahead should I book a flight from Santa Cruz de la Sierra to Madrid?

Use this chart to determine the optimal time to book a round-trip flight from Santa Cruz de la Sierra to Madrid. Price data was last updated on September 12, 2025.

To ensure you get the cheapest price possible for a flight from Santa Cruz de la Sierra to Madrid, you should look to book at least 87 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Santa Cruz de la Sierra to Madrid?

Currently, November is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Madrid (average of $543). Flying from Santa Cruz de la Sierra to Madrid in June is currently the most expensive (average of $1,054). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from VVI to MAD?

Find hourly flight availability from Santa Cruz de la Sierra to Madrid. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

It’s optimal to fly from Santa Cruz de la Sierra to Madrid in the afternoon. By choosing this option you can save up to 25% on the cost of your flight, compared to a flight in the morning.

How much does it cost to fly round-trip from Santa Cruz de la Sierra to Madrid?

Reviews of airlines servicing Madrid

Get insights into the airlines that provide service to Madrid. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Madrid. Reviews last updated September 15, 2025.
Peruse reviews from past customers who have flown with Air Europa, Iberia, and BoA from Santa Cruz de la Sierra to Madrid to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Air Europa
7.0
Good
556 reviews

Entertainment

6.6

Crew

7.5

Comfort

7.0

Overall

7.0

Food

6.3

Boarding

7.1

Reviews

1 / 10
8.0
Excellent

Christina,Jun 2025

ALC - MAD

It would be nice to have free messaging wifi on a trans Atlantic flight
Air Europa
7.0
Good
556 reviews
Air Europa
7.0
Good
556 reviews

Entertainment

6.6

Crew

7.5

Comfort

7.0

Overall

7.0

Food

6.3

Boarding

7.1

Reviews

1 / 10
8.0
Excellent

Christina,Jun 2025

ALC - MAD

It would be nice to have free messaging wifi on a trans Atlantic flight
Iberia
7.0
Good
2,924 reviews
Air Europa
7.0
Good
556 reviews

Entertainment

6.6

Crew

7.5

Comfort

7.0

Overall

7.0

Food

6.3

Boarding

7.1

Reviews

1 / 10
8.0
Excellent

Christina,Jun 2025

ALC - MAD

It would be nice to have free messaging wifi on a trans Atlantic flight
BoA
6.8
Okay
136 reviews
Air Europa
7.0
Good
556 reviews

Entertainment

6.6

Crew

7.5

Comfort

7.0

Overall

7.0

Food

6.3

Boarding

7.1

Reviews

1 / 10
8.0
Excellent

Christina,Jun 2025

ALC - MAD

It would be nice to have free messaging wifi on a trans Atlantic flight
Avianca
6.7
Okay
2,435 reviews
Air Europa
7.0
Good
556 reviews

Entertainment

6.6

Crew

7.5

Comfort

7.0

Overall

7.0

Food

6.3

Boarding

7.1

Reviews

1 / 10
8.0
Excellent

Christina,Jun 2025

ALC - MAD

It would be nice to have free messaging wifi on a trans Atlantic flight

Related info for your journey

Find useful and relevant information for your journey from Santa Cruz de la Sierra to Madrid. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Santa Cruz de la Sierra to Madrid?

    Booking a flight from Santa Cruz de la Sierra Viru Viru Intl (VVI) to Madrid Barajas (MAD) is your only option if you wish to fly from Santa Cruz de la Sierra to Madrid. On a typical day, there is 1 flight from Viru Viru Intl to Barajas, all of which are around 10h 45m for a nonstop flight. You can also purchase a plane ticket from 4 airlines when you book a flight from Viru Viru Intl to Madrid.

  • How popular is this Santa Cruz de la Sierra to Madrid flight route?

    The Santa Cruz de la Sierra Viru Viru Intl to Madrid Barajas flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Santa Cruz de la Sierra to Madrid?

    A quick flight from Santa Cruz de la Sierra to Madrid can take about 10h 40m. Air Europa provides one of the quickest options available for as low as $943. The distance between Santa Cruz de la Sierra and Madrid is about 5537 mi. Most flights are nonstop.

  • What are the cheapest airlines flying from Santa Cruz de la Sierra to Madrid round-trip?

    According to our current data, Iberia ($554), Air Europa ($885), and BoA ($895) offers the cheapest pricing from Santa Cruz de la Sierra to Madrid. Users have found that Iberia is 49% cheaper than the other options available to this destination.

  • What are the most reliable airlines from Santa Cruz de la Sierra to Madrid?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Santa Cruz de la Sierra to Madrid on time: Air Europa (94%), BoA (13%), Iberia (13%).

  • What are the cheapest flights from Santa Cruz de la Sierra to Madrid?

    Looking for the cheapest flight from Santa Cruz de la Sierra to Madrid? While on average our users pay $1,016, our data indicates the cheapest price to be $512. The most popular route (Santa Cruz de la Sierra Viru Viru Intl - Madrid Barajas), is priced around $1,051.

  • Can I find deals for flights from Santa Cruz de la Sierra to Madrid that include hotel bookings?

    Yes. In addition to deals on Santa Cruz de la Sierra to Madrid flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Cruz de la Sierra to Madrid?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Cruz de la Sierra to Madrid.

  • Can I find deals for business class flights from Santa Cruz de la Sierra to Madrid?

    Yes. Cheapflights offers flight deals from Santa Cruz de la Sierra to Madrid by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Cruz de la Sierra to Madrid?

    Currently, November is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Madrid (average of $543). Flying from Santa Cruz de la Sierra to Madrid in June is currently the most expensive (average of $1,054). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Madrid?

Book flights to Madrid if you plan to visit one of these locations
Fuenlabrada
Getafe

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Alternative routes for Santa Cruz de la Sierra to Madrid

See prices for flight routes from nearby airports that may be better suited for you.
Cochabamba to Madrid flights
La Paz to Madrid flights

Top 4 airlines flying from Santa Cruz de la Sierra to Madrid

Discover the top 4 airlines that operate flights from Santa Cruz de la Sierra to Madrid. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
IberiaCheapest$554Average$934FlexibilityNo cancel feeOn-time77%
Air EuropaCheapest$885Average$1,222FlexibilityNo cancel feeOn-time83%
BoACheapest$895Average$1,304FlexibilityNo cancel feeOn-timeN/A
AviancaCheapest$912Average$1,241FlexibilityNo cancel feeOn-time71%

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