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Santa Cruz de la Sierra

$424+ Cheap flights from Madrid, Spain (MAD) to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/14. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — VVI
Jul 24 — Jul 311
Fri 7/24
Fri 7/31
1 adult, Economy
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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

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Cheapflights Tip: The best prices from Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl are usually found in April or September, booked 56 days in advance, depart on a Thursday or Wednesday and return on a Friday

Cheap flight deals from Madrid to Santa Cruz de la Sierra

Cheapest flights from Madrid to Santa Cruz de la Sierra
Explore the most affordable flight options available from Madrid to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 24, 2026.

This Trip.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1611:05 am
MAD
-
VVI
1 stop21h 25m
Multiple Airlines
Tue 9/2912:20 pm
VVI
-
MAD
Nonstop10h 50m
Multiple Airlines
Deal found 6/23$1,027
This CheapOair deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/58:10 am
MAD
-
VVI
1 stop24h 20m
Multiple Airlines
Thu 9/2412:20 pm
VVI
-
MAD
Nonstop10h 50m
Multiple Airlines
Deal found 6/23$1,028
This Avianca deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/122:20 am
MAD
-
VVI
1 stop30h 10m
Avianca
Wed 10/73:35 am
VVI
-
MAD
1 stop28h 30m
Avianca
Deal found 6/23$1,030
This Avianca deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/148:10 am
MAD
-
VVI
1 stop24h 20m
Avianca
Mon 10/53:35 am
VVI
-
MAD
1 stop14h 45m
Avianca
Deal found 6/21$1,031
This Avianca deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1611:05 am
MAD
-
VVI
1 stop21h 25m
Avianca
Sat 10/33:35 am
VVI
-
MAD
2 stops29h 25m
Avianca
Deal found 6/23$1,032
This Avianca deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/168:10 am
MAD
-
VVI
1 stop24h 20m
Avianca
Mon 10/53:35 am
VVI
-
MAD
2 stops26h 25m
Avianca
Deal found 6/21$1,033
This Avianca deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/28:10 am
MAD
-
VVI
1 stop24h 20m
Avianca
Sun 9/203:35 am
VVI
-
MAD
1 stop20h 35m
Avianca
Deal found 6/23$1,034
This Avianca deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/182:20 am
MAD
-
VVI
1 stop30h 10m
Avianca
Mon 10/53:35 am
VVI
-
MAD
2 stops25h 35m
Avianca
Deal found 6/23$1,036
This Avianca deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/182:20 am
MAD
-
VVI
1 stop30h 10m
Avianca
Tue 10/133:35 am
VVI
-
MAD
2 stops26h 25m
Avianca
Deal found 6/21$1,037
This FlightHub deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/42:50 am
MAD
-
VVI
Nonstop11h 15m
Air Europa
Thu 9/2412:20 pm
VVI
-
MAD
Nonstop10h 50m
Air Europa
Deal found 6/23$1,039

Find flight deals from Madrid to Santa Cruz de la Sierra

Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$1,027
(Trip.com)

One-way from

$424
(Kiwi.com)

Popular in

July

Cheapest in

April

Average price

$1,076
Provider with most accurate pricing for Madrid Barajas-Santa Cruz de la Sierra Viru Viru Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Madrid Barajas-Santa Cruz de la Sierra Viru Viru Intl flights.
Search Deals
From Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
One-way flight from Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($209 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($37 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Madrid to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 24, 2026.
Use the filters below to find and compare flights from Madrid to Santa Cruz de la Sierra that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Fri 9/18

10:50 am-3:38 am

2 stops22h 48m

Santa Cruz de la Sierra Viru Viru Intl

Sat 10/3

11:47 am-8:05 am

2 stops38h 18m

$1,278

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Tue 9/15

11:15 am-10:44 pm

2 stops41h 29m

Santa Cruz de la Sierra Viru Viru Intl

Sat 10/3

11:47 am-8:05 am

2 stops38h 18m

$1,278

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Mon 9/21

11:15 am-3:38 am

2 stops22h 23m

Santa Cruz de la Sierra Viru Viru Intl

Sat 10/10

11:47 am-8:05 am

2 stops38h 18m

$1,278

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Wed 9/23

11:15 am-3:38 am

2 stops22h 23m

Santa Cruz de la Sierra Viru Viru Intl

Mon 10/12

11:47 am-8:05 am

2 stops38h 18m

$1,279

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Wed 9/23

11:15 am-10:44 pm

2 stops41h 29m

Santa Cruz de la Sierra Viru Viru Intl

Sat 10/10

11:47 am-8:05 am

2 stops38h 18m

$1,279

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Sat 9/19

11:15 am-10:44 pm

2 stops41h 29m

Santa Cruz de la Sierra Viru Viru Intl

Mon 10/5

11:47 am-8:05 am

2 stops38h 18m

$1,478

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Sat 9/19

11:15 am-10:44 pm

2 stops41h 29m

Santa Cruz de la Sierra Viru Viru Intl

Sat 10/10

11:47 am-8:05 am

2 stops38h 18m

$1,480

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Sun 11/22

11:00 am-10:38 pm

2 stops40h 38m

Santa Cruz de la Sierra Viru Viru Intl

Wed 12/2

11:42 am-7:45 am

2 stops39h 03m

$1,493
Quickest round-trip

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Fri 7/10

8:10 am-2:30 am

1 stop24h 20m

Santa Cruz de la Sierra Viru Viru Intl

Thu 8/6

3:35 am-2:05 pm

1 stop28h 30m

$1,556

MadridSanta Cruz de la Sierra

MAD - VVI

MADVVI

Madrid Barajas

Fri 9/18

11:15 am-10:44 pm

2 stops41h 29m

Santa Cruz de la Sierra Viru Viru Intl

Tue 10/6

11:47 am-9:00 am

2 stops39h 13m

$1,593

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/22

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

Compare providers for flights from Madrid to Santa Cruz de la Sierra

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Madrid to Santa Cruz de la Sierra in June.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
Trip.comPrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Madrid-Santa Cruz de la Sierra flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Madrid-Santa Cruz de la Sierra flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Madrid-Santa Cruz de la Sierra flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Madrid-Santa Cruz de la Sierra flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Madrid-Santa Cruz de la Sierra flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Madrid to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Madrid with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to Santa Cruz de la Sierra

How far ahead should I book a flight from Madrid to Santa Cruz de la Sierra?

The best time to book flights from Madrid to Santa Cruz de la Sierra is 55 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Madrid to Santa Cruz de la Sierra?

Currently, April is the cheapest month in which you can book a flight from Madrid to Santa Cruz de la Sierra (average of $846). Flying from Madrid to Santa Cruz de la Sierra in July is currently the most expensive (average of $1,459). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAD to VVI?

Find hourly flight availability from Madrid to Santa Cruz de la Sierra. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 24, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Madrid to Santa Cruz de la Sierra as you normally would.

How much does it cost to fly round-trip from Madrid to Santa Cruz de la Sierra?

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated June 24, 2026.
Read through reviews of airlines operating flights from Madrid to Santa Cruz de la Sierra, such as Iberia,BoA, andAvianca. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Iberia
7.0
Good
3,246 reviews

Boarding

7.2

Entertainment

6.6

Crew

7.7

Food

6.3

Comfort

6.7

Overall

7.0

Reviews

1 / 20
10.0
Excellent

Sylvie,Dec 2025

MAD - DSS

No space ,no confortable, and not organised at all àd very tiring and I booked my seat in advance
Iberia
7.0
Good
3,246 reviews
Iberia
7.0
Good
3,246 reviews

Boarding

7.2

Entertainment

6.6

Crew

7.7

Food

6.3

Comfort

6.7

Overall

7.0

Reviews

1 / 20
10.0
Excellent

Sylvie,Dec 2025

MAD - DSS

No space ,no confortable, and not organised at all àd very tiring and I booked my seat in advance
BoA
6.8
Okay
132 reviews
Iberia
7.0
Good
3,246 reviews

Boarding

7.2

Entertainment

6.6

Crew

7.7

Food

6.3

Comfort

6.7

Overall

7.0

Reviews

1 / 20
10.0
Excellent

Sylvie,Dec 2025

MAD - DSS

No space ,no confortable, and not organised at all àd very tiring and I booked my seat in advance
Avianca
6.5
Okay
2,534 reviews
Iberia
7.0
Good
3,246 reviews

Boarding

7.2

Entertainment

6.6

Crew

7.7

Food

6.3

Comfort

6.7

Overall

7.0

Reviews

1 / 20
10.0
Excellent

Sylvie,Dec 2025

MAD - DSS

No space ,no confortable, and not organised at all àd very tiring and I booked my seat in advance

Related info for your journey

Find useful and relevant information for your journey from Madrid to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Madrid to Santa Cruz de la Sierra?

    If you wish to fly to Santa Cruz de la Sierra from Madrid, then you need to book flights from Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl. There is 1 flight from Barajas (MAD) to Viru Viru Intl (VVI) per day to choose from. Flights to Santa Cruz de la Sierra from Barajas are available from 3 different airlines, which means you should have some options if you want to compare airfare deals. 11h 15m is how long a nonstop flight from Madrid to Santa Cruz de la Sierra Viru Viru Intl typically takes.

  • How long is the flight from Madrid to Santa Cruz de la Sierra?

    There are many flights that can get you from Madrid to Santa Cruz de la Sierra in 22h 48m. Fly via United Airlines to get the fastest option. There are 5537 mi between Madrid and Santa Cruz de la Sierra.

  • What are the cheapest airlines flying from Madrid to Santa Cruz de la Sierra round-trip?

    Avianca, at $696, was found to be the cheapest airline from Madrid to Santa Cruz de la Sierra.Alternate airlines to your destination round-trip include BoA and Iberia. Avianca is 34% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Madrid to Santa Cruz de la Sierra one-way?

    The cheapest airline one-way is Avianca, with whom users have recently found tickets for as low as $224. However, be on the lookout for offers from BoA and Air Europa, as they are both options that can get you from Madrid to Santa Cruz de la Sierra for a low price.

  • What are the most reliable airlines from Madrid to Santa Cruz de la Sierra?

    The top 3 most reliable airlines when flying from Madrid to Santa Cruz de la Sierra are Air Europa (68%), BoA (24%) and Iberia (24%).

  • What are the cheapest flights from Madrid to Santa Cruz de la Sierra?

    Looking at all options, your cheapest flight can be booked for $414. While the most popular route (Madrid Barajas - Santa Cruz de la Sierra Viru Viru Intl) can be booked for $1,028 on average, our data indicates $860 when flying from Madrid to Santa Cruz de la Sierra.

  • Can I find deals for flights from Madrid to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Madrid to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Madrid to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Madrid to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Madrid to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to Santa Cruz de la Sierra?

    Currently, April is the cheapest month in which you can book a flight from Madrid to Santa Cruz de la Sierra (average of $846). Flying from Madrid to Santa Cruz de la Sierra in July is currently the most expensive (average of $1,459). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Madrid to Santa Cruz de la Sierra

See prices for flight routes from nearby airports that may be better suited for you.
Madrid to La Paz flights

Top 3 airlines flying from Madrid to Santa Cruz de la Sierra

Discover the top 3 airlines that operate flights from Madrid to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$696Average$810FlexibilityNo cancel feeOn-time71%
BoACheapest$744Average$1,301FlexibilityNo cancel feeOn-timeN/A
IberiaCheapest$831Average$1,201FlexibilityNo cancel feeOn-time77%

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