What’s the cheapest layover airport for flights from Santa Ana, California to Madrid?

Chicago (ORD) is the most affordable 1-stop option, with an average round-trip price of $538.

What’s the fastest layover option from Santa Ana, California to Madrid?

Flights via Dallas (DFW) have the shortest average one-way travel time for 1-stop routes: 13h 59m.

What’s the top layover airport for flights from Santa Ana, California to Madrid?

Chicago (ORD) – chosen by Cheapflights users on 63% of 1-stop itineraries from Santa Ana, California to Madrid on Cheapflights.

Which airport typically offers the quickest layover for flights from Santa Ana, California to Madrid?

Flights via Dallas (DFW) offer the fastest connection on this route, with an average layover time of 1h 47m.

How long is the flight from Santa Ana, California to Madrid?

British Airways and United Airlines can get you from Santa Ana, California to Madrid in just under 17h 30m. Your travel time can differ by up to 18h 03m. Santa Ana, California and Madrid are separated by a distance of 5820 mi. Both multi-stop and nonstop flights can be found to your destination and back.

What are the cheapest airlines flying from Santa Ana, California to Madrid round-trip?

Flying on British Airways is currently your cheapest option to Madrid, with prices starting at $521. Another option worth looking into is American Airlines, starting at $523 round trip. These flights start at 43% lower than the current average price 3 months from now.

In terms of precipitation, rainfall in Madrid ranges from 0.4 - 2.4 inches per month. November is typically the wettest month, when rainfall can reach 2.4 in. July is typically the driest time to visit Madrid when rainfall is around 0.4 in.

If weather is an important factor for your trip to Madrid, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

Most accurate provider : When it comes to deals on Santa Ana, California-Madrid flights, users find the pricing of Justfly.com to be most consistent on Cheapflights vs. Justfly.com Users can find the same prices on Santa Ana, California-Madrid flight deals on Cheapflights vs. Justfly.com >95% of the time. Price accuracy is based on data collected from Santa Ana, California-Madrid flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Santa Ana, California-Madrid flights, Cheapflights users trust Justfly.com the most. Justfly.com has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana, California-Madrid flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Santa Ana to Madrid that include hotel bookings?

Yes. In addition to deals on Santa Ana to Madrid flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Santa Ana to Madrid?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to Madrid.

Can I find deals for business class flights from Santa Ana to Madrid?

Yes. Cheapflights offers flight deals from Santa Ana to Madrid by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$425+ Flights from Santa Ana, CA to Madrid, Spain

Q: How much does it cost to fly round-trip from Santa Ana, California to Madrid?

Airfare is below average for this route at the moment. Santa Ana, California to Madrid flights typically cost between $1,052 and $1,418 in January. The cheapest round-trip price found within the last 3 days was $510 on British Airways (Jan 28-Feb 11).

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Santa Ana to Madrid with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Santa Ana to Madrid

Cheapest flights from Santa Ana to Madrid
Explore the most affordable flight options available from Santa Ana to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 14, 2025.

Wed 12/319:17 amSNA - MAD

1 stop15h 08mBritish Airways

Tue 3/3112:40 pmMAD - SNA

1 stop16h 43mBritish Airways

Deal found 12/13

$690

Tue 12/306:45 amSNA - MAD

1 stop14h 30mIberia

Thu 1/151:00 pmMAD - SNA

1 stop18h 56mIberia

Deal found 12/13

$990

Tue 12/232:47 pmSNA - MAD

1 stop33h 38mBritish Airways

Sat 1/171:00 pmMAD - SNA

1 stop16h 55mBritish Airways

Deal found 12/13

$1,045

Tue 12/232:16 pmSNA - MAD

2 stops56h 44mAir Canada

Thu 1/81:35 pmMAD - SNA

2 stops34h 35mAir Canada

Deal found 12/14

$1,376

Mon 12/1510:41 amSNA - MAD

1 stop13h 44mBritish Airways

Mon 12/228:50 pmMAD - SNA

2 stops34h 40mBritish Airways

Deal found 12/14

$1,465

Mon 12/154:25 pmSNA - MAD

2 stops17h 00mBritish Airways

Tue 12/238:50 pmMAD - SNA

2 stops51h 59mBritish Airways

Deal found 12/14

$1,472

Tue 12/232:47 pmSNA - MAD

1 stop33h 38mMultiple Airlines

Thu 1/89:40 pmMAD - SNA

2 stops32h 15mMultiple Airlines

Deal found 12/13

$1,555

Tue 12/236:45 amSNA - MAD

1 stop17h 30mKLM

Thu 1/87:05 amMAD - SNA

2 stops22h 27mKLM

Deal found 12/12

$1,560

Best flights from Santa Ana to Madrid
Discover carefully curated flight deals from Santa Ana to Madrid that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 14, 2025.

Wed 1/2812:52 pmSNA - MAD

2 stops19h 03mBritish Airways

Wed 2/1112:40 pmMAD - SNA

1 stop17h 15mBritish Airways

Deal found 12/13

$510

Wed 1/286:45 amSNA - MAD

2 stops17h 30mUnited Airlines

Wed 2/48:30 amMAD - SNA

3 stops22h 54mUnited Airlines

Deal found 12/14

$528

Mon 5/1111:55 amSNA - MAD

1 stop15h 20mDelta

Wed 5/2712:40 pmMAD - SNA

2 stops31h 15mDelta

Deal found 12/13

$756

Sat 1/179:30 amSNA - MAD

2 stops17h 25mMultiple Airlines

Wed 1/2812:55 amMAD - SNA

1 stop16h 39mMultiple Airlines

Deal found 12/12

$779

Sat 1/1712:52 pmSNA - MAD

1 stop35h 33mBritish Airways

Thu 1/291:00 pmMAD - SNA

1 stop16h 55mBritish Airways

Deal found 12/14

$526

Thu 2/199:23 amSNA - MAD

1 stop15h 02mBritish Airways

Wed 2/2512:40 pmMAD - SNA

1 stop16h 43mBritish Airways

Deal found 12/13

$570

Mon 4/138:11 amSNA - MAD

1 stop20h 14mBritish Airways

Tue 5/1212:40 pmMAD - SNA

1 stop16h 32mBritish Airways

Deal found 12/14

$690

Sat 3/73:12 pmSNA - MAD

1 stop33h 13mBritish Airways

Sun 3/151:45 pmMAD - SNA

1 stop15h 44mBritish Airways

Deal found 12/14

$746

Tue 4/73:21 pmSNA - MAD

1 stop13h 04mBritish Airways

Mon 4/2012:40 pmMAD - SNA

1 stop18h 28mBritish Airways

Deal found 12/14

$750

Wed 2/111:54 pmSNA - MAD

2 stops18h 01mBritish Airways

Sun 2/1512:40 pmMAD - SNA

1 stop19h 06mBritish Airways

Deal found 12/12

$769

Last-minute flights from Santa Ana to Madrid
Discover last-minute flight deals from Santa Ana to Madrid. Data last updated December 14, 2025 and is based on user searches.

Sat 1/103:15 pmSNA - MAD

1 stop33h 10mBritish Airways

Sun 1/1810:35 amMAD - SNA

2 stops20h 14mBritish Airways

Deal found 12/14

$614

Mon 1/121:54 pmSNA - MAD

2 stops18h 01mBritish Airways

Mon 1/191:15 pmMAD - SNA

2 stops41h 46mBritish Airways

Deal found 12/13

$591

Mon 1/121:54 pmSNA - MAD

2 stops18h 01mBritish Airways

Sun 1/1810:35 amMAD - SNA

2 stops20h 14mBritish Airways

Deal found 12/14

$598

Mon 1/123:15 pmSNA - MAD

1 stop33h 10mBritish Airways

Thu 2/1212:40 pmMAD - SNA

1 stop16h 43mBritish Airways

Deal found 12/13

$610

Tue 1/139:30 amSNA - MAD

1 stop14h 55mBritish Airways

Tue 1/201:00 pmMAD - SNA

1 stop16h 55mBritish Airways

Deal found 12/14

$603

Sat 1/1712:52 pmSNA - MAD

1 stop35h 33mBritish Airways

Thu 1/291:00 pmMAD - SNA

1 stop16h 55mBritish Airways

Deal found 12/14

$526

Sat 1/243:15 pmSNA - MAD

1 stop33h 10mBritish Airways

Sun 2/1512:40 pmMAD - SNA

1 stop16h 43mBritish Airways

Deal found 12/13

$576

Wed 1/2812:52 pmSNA - MAD

2 stops19h 03mBritish Airways

Wed 2/1112:40 pmMAD - SNA

1 stop17h 15mBritish Airways

Deal found 12/13

$510

Wed 1/287:00 amSNA - MAD

2 stops16h 00mMultiple Airlines

Wed 2/48:30 amMAD - SNA

2 stops41h 58mMultiple Airlines

Deal found 12/14

$517

Wed 1/286:45 amSNA - MAD

2 stops17h 30mUnited Airlines

Wed 2/48:30 amMAD - SNA

3 stops22h 54mUnited Airlines

Deal found 12/14

$528

One-way flights from Santa Ana to Madrid
Search for one-way flight options from Santa Ana to Madrid. Find affordable one-way fares based on user searches. Data last updated December 14, 2025.

Mon 1/124:23 pmSNA - MAD

2 stops17h 02mBritish Airways

Deal found 12/14

$425

Wed 3/1811:41 amSNA - MAD

1 stop13h 54mBritish Airways

Deal found 12/13

$430

Mon 3/232:47 pmSNA - MAD

2 stops18h 08mBritish Airways

Deal found 12/14

$432

Tue 1/139:30 amSNA - MAD

1 stop14h 55mBritish Airways

Deal found 12/14

$436

Sat 2/711:42 amSNA - MAD

2 stops39h 13mBritish Airways

Deal found 12/14

$440

Sat 3/143:24 pmSNA - MAD

1 stop34h 11mBritish Airways

Deal found 12/13

$451

Thu 1/154:23 pmSNA - MAD

2 stops17h 02mBritish Airways

Deal found 12/14

$475

Wed 1/143:15 pmSNA - MAD

1 stop33h 10mBritish Airways

Deal found 12/14

$500

Fri 3/133:24 pmSNA - MAD

1 stop34h 11mBritish Airways

Deal found 12/13

$503

Find flight deals from Santa Ana to Madrid

Most accurate provider	Justfly.com 3 stars
Most trusted provider	Justfly.com 3 stars
Round-trip from	$510 (oojo)
One-way from	$425 (oojo)
Popular in	June
Cheapest in	November
Average price	$1,418

Provider with most accurate pricing for Santa Ana J. Wayne/Orange Cnty-Madrid Barajas flight deals.

Search Deals

Provider most trusted by Cheapflights users for Santa Ana J. Wayne/Orange Cnty-Madrid Barajas flights.

Search Deals

From Santa Ana J. Wayne/Orange Cnty to Madrid Barajas

Search Deals

One-way flight from Santa Ana J. Wayne/Orange Cnty to Madrid Barajas

Search Deals

Highest demand for flights based on searches. 32% potential increase in price ($435 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 8% potential price decrease ($70 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaMadrid

SNA - MAD

SNAMAD

Santa Ana J. Wayne/Orange Cnty

Wed 1/28

12:52 pm-4:55 pm

2 stops19h 03m

Madrid Barajas

Wed 2/11

12:40 pm-8:55 pm

1 stop17h 15m

$510

Santa AnaMadrid

SNA - MAD

SNAMAD

Santa Ana J. Wayne/Orange Cnty

Sat 1/17

12:52 pm-9:25 am

1 stop35h 33m

Madrid Barajas

Thu 1/29

1:00 pm-8:55 pm

1 stop16h 55m

$526

Santa AnaMadrid

SNA - MAD

SNAMAD

Santa Ana J. Wayne/Orange Cnty

Wed 1/28

6:45 am-9:15 am

2 stops17h 30m

Madrid Barajas

Wed 2/4

8:30 am-10:24 pm

3 stops22h 54m

$528

Santa AnaMadrid

SNA - MAD

SNAMAD

Santa Ana J. Wayne/Orange Cnty

Thu 2/19

9:23 am-9:25 am

1 stop15h 02m

Madrid Barajas

Wed 2/25

12:40 pm-8:23 pm

1 stop16h 43m

$570

Santa AnaMadrid

SNA - MAD

SNAMAD

Santa Ana J. Wayne/Orange Cnty

Mon 4/13

8:11 am-1:25 pm

1 stop20h 14m

Madrid Barajas

Tue 5/12

12:40 pm-8:12 pm

1 stop16h 32m

$690

Santa AnaMadrid

SNA - MAD

SNAMAD

Santa Ana J. Wayne/Orange Cnty

Sat 3/7

3:12 pm-9:25 am

1 stop33h 13m

Madrid Barajas

Sun 3/15

1:45 pm-9:29 pm

1 stop15h 44m

$746

Santa AnaMadrid

SNA - MAD

SNAMAD

Santa Ana J. Wayne/Orange Cnty

Tue 4/7

3:21 pm-1:25 pm

1 stop13h 04m

Madrid Barajas

Mon 4/20

12:40 pm-10:08 pm

1 stop18h 28m

$750

Santa AnaMadrid

SNA - MAD

SNAMAD

Santa Ana J. Wayne/Orange Cnty

Mon 5/11

11:55 am-12:15 pm

1 stop15h 20m

Madrid Barajas

Wed 5/27

12:40 pm-10:55 am

2 stops31h 15m

$756

Santa AnaMadrid

SNA - MAD

SNAMAD

Santa Ana J. Wayne/Orange Cnty

Wed 2/11

1:54 pm-4:55 pm

2 stops18h 01m

Madrid Barajas

Sun 2/15

12:40 pm-10:46 pm

1 stop19h 06m

$769

Santa AnaMadrid

SNA - MAD

SNAMAD

Santa Ana J. Wayne/Orange Cnty

Sat 1/17

9:30 am-11:55 am

2 stops17h 25m

Madrid Barajas

Wed 1/28

12:55 am-8:34 am

1 stop16h 39m

$779

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/14

Showing 1-10 of 18 results

Compare providers for flights from Santa Ana to Madrid

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Ana to Madrid in December.

Provider	Price Accuracy	Trust Score*
FlightHub	Price Accuracy3 stars	Trust Score*1 star
Ovago	Price Accuracy2 stars	Trust Score*2 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars
Trip.com	Price Accuracy2 stars	Trust Score*3 stars
Justfly.com	Price Accuracy3 stars	Trust Score*3 stars
Gurufare	Price Accuracy2 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Santa Ana, California-Madrid flights, users find the pricing of Justfly.com to be most consistent on Cheapflights vs. Justfly.com Users can find the same prices on Santa Ana, California-Madrid flight deals on Cheapflights vs. Justfly.com >95% of the time. Price accuracy is based on data collected from Santa Ana, California-Madrid flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Santa Ana, California-Madrid flights, Cheapflights users trust Justfly.com the most. Justfly.com has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana, California-Madrid flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santa Ana to Madrid

Have a flexible travel schedule? Discover the best time to fly to Madrid from Santa Ana with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to Madrid

Prices

What is the cheapest month to book a flight from Santa Ana, California to Madrid?

Currently, November is the cheapest month in which you can book a flight from Santa Ana, California to Madrid (average of $340). Flying from Santa Ana, California to Madrid in June is currently the most expensive (average of $665). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SNA to MAD?

It’s optimal to fly from Santa Ana, California to Madrid at noon. By choosing this option you can save up to 15% on the cost of your flight, compared to a flight in the morning.

How much does it cost to fly round-trip from Santa Ana, California to Madrid?

Reviews of airlines servicing Madrid

Get a feel of what it's like to fly with American Airlines and British Airways from Santa Ana to Madrid by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

American Airlines

7.2

Good

11,054 reviews

Reviews

1 / 20

10.0

Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

American Airlines

7.2

Good

11,054 reviews

American Airlines

7.2

Good

11,054 reviews

Reviews

1 / 20

10.0

Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

British Airways

6.7

Okay

7,574 reviews

American Airlines

7.2

Good

11,054 reviews

Reviews

1 / 20

10.0

Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

Related info for your journey

How long is the flight from Santa Ana, California to Madrid?
British Airways and United Airlines can get you from Santa Ana, California to Madrid in just under 17h 30m. Your travel time can differ by up to 18h 03m. Santa Ana, California and Madrid are separated by a distance of 5820 mi. Both multi-stop and nonstop flights can be found to your destination and back.
What are the cheapest airlines flying from Santa Ana, California to Madrid round-trip?
Flying on British Airways is currently your cheapest option to Madrid, with prices starting at $521. Another option worth looking into is American Airlines, starting at $523 round trip. These flights start at 43% lower than the current average price 3 months from now.
Can I find deals for flights from Santa Ana to Madrid that include hotel bookings?
Yes. In addition to deals on Santa Ana to Madrid flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Santa Ana to Madrid?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to Madrid.
Can I find deals for business class flights from Santa Ana to Madrid?
Yes. Cheapflights offers flight deals from Santa Ana to Madrid by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Santa Ana, California to Madrid?
Currently, November is the cheapest month in which you can book a flight from Santa Ana, California to Madrid (average of $340). Flying from Santa Ana, California to Madrid in June is currently the most expensive (average of $665). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Getafe

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Santa Ana to Madrid

Los Angeles to Madrid flights

San Francisco to Madrid flights

Ontario to Madrid flights

San Diego to Madrid flights

San Jose to Madrid flights

Las Vegas to Madrid flights

Sacramento to Madrid flights

Fresno to Madrid flights

Oakland to Madrid flights

Burbank to Madrid flights

Reno to Madrid flights

Monterey to Madrid flights

Long Beach to Madrid flights

Santa Rosa to Madrid flights

Santa Barbara to Madrid flights

Medford to Madrid flights

Arcata to Madrid flights

Tijuana to Madrid flights

Other flights to Madrid

Top 2 airlines flying from Santa Ana to Madrid

Airline	Cheapest	Average	Flexibility	On-time
British Airways	Cheapest$521	Average$606	FlexibilityNo cancel fee	On-time70%
American Airlines	Cheapest$523	Average$999	FlexibilityNo cancel fee	On-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$425+ Cheap flights from Santa Ana, CA (SNA) to Madrid, Spain (MAD)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/12. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Santa Ana to Madrid with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Santa Ana to Madrid

Cheapest flights from Santa Ana to MadridExplore the most affordable flight options available from Santa Ana to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 14, 2025.

Explore the most affordable flight options available from Santa Ana to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 14, 2025.

Find flight deals from Santa Ana to Madrid

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santa Ana to Madrid that are best for you.

Compare providers for flights from Santa Ana to Madrid

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Ana to Madrid in December.

Best time to book a flight from Santa Ana to Madrid

Have a flexible travel schedule? Discover the best time to fly to Madrid from Santa Ana with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to Madrid

What is the cheapest month to book a flight from Santa Ana, California to Madrid?

What is the cheapest time of day to fly from SNA to MAD?

How much does it cost to fly round-trip from Santa Ana, California to Madrid?

What’s the top layover airport for flights from Santa Ana, California to Madrid?

What’s the cheapest layover airport for flights from Santa Ana, California to Madrid?

What’s the fastest layover option from Santa Ana, California to Madrid?

Which airport typically offers the quickest layover for flights from Santa Ana, California to Madrid?

Reviews of airlines servicing Madrid

Get a feel of what it's like to fly with American Airlines and British Airways from Santa Ana to Madrid by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Santa Ana to Madrid. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Santa Ana, California to Madrid?

What are the cheapest airlines flying from Santa Ana, California to Madrid round-trip?

Can I find deals for flights from Santa Ana to Madrid that include hotel bookings?

How can I find direct flights from Santa Ana to Madrid?

Can I find deals for business class flights from Santa Ana to Madrid?

What is the cheapest month to book a flight from Santa Ana, California to Madrid?

Traveling to a place near Madrid?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Santa Ana to Madrid

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Santa Ana to Madrid

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Santa Ana to Madrid
Explore the most affordable flight options available from Santa Ana to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 14, 2025.