$320+ Cheap flights from Missouri to Madrid, Spain (MAD)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/13. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MAD
Mar 6 — Mar 131
1 adult, Economy
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Cheapest flights from Missouri to MadridExplore the most affordable flight options available from Missouri to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.
Explore the most affordable flight options available from Missouri to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.
This Flighttix deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:16 pm
MCI
- MAD
2 stops30h 44m
Virgin Atlantic
Mon 3/169:00 am
MAD
- MCI
2 stops19h 04m
Virgin Atlantic
Deal found 2/2![Virgin Atlantic logo]()
$464
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/21:23 pm
MCI
- MAD
1 stop12h 52m
KLM
Tue 3/176:00 am
MAD
- MCI
2 stops16h 55m
KLM
Deal found 2/2![KLM logo]()
$466
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/38:00 am
MCI
- MAD
3 stops17h 00m
United Airlines
Tue 3/1012:40 pm
MAD
- MCI
2 stops27h 51m
United Airlines
Deal found 2/3![United Airlines logo]()
$475
This Finnair deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/27:05 am
MCI
- MAD
1 stop18h 05m
Multiple Airlines
Mon 3/1611:30 am
MAD
- MCI
1 stop16h 34m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$478
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:30 am
STL
- MAD
1 stop18h 30m
Delta
Wed 3/189:00 am
MAD
- STL
2 stops20h 58m
Delta
Deal found 2/2![Delta logo]()
$478
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/412:15 pm
STL
- MAD
2 stops21h 25m
United Airlines
Thu 3/1212:40 pm
MAD
- STL
2 stops35h 20m
United Airlines
Deal found 2/3![United Airlines logo]()
$480
This oojo deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/204:17 pm
MCI
- MAD
1 stop14h 13m
British Airways
Thu 4/303:25 pm
MAD
- MCI
1 stop13h 31m
British Airways
Deal found 2/3![British Airways logo]()
$488
This Cheapflightsfares deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/43:50 pm
STL
- MAD
1 stop21h 25m
Lufthansa
Thu 3/126:00 am
MAD
- STL
2 stops22h 59m
Lufthansa
Deal found 2/4![Lufthansa logo]()
$488
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/95:54 am
MCI
- MAD
1 stop20h 11m
Delta
Wed 3/1810:05 am
MAD
- MCI
1 stop29h 20m
Delta
Deal found 2/3![Delta logo]()
$491
This Finnair deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/47:05 am
STL
- MAD
1 stop16h 15m
Multiple Airlines
Thu 3/1211:30 am
MAD
- STL
1 stop18h 28m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$491
This Finnair deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:19 am
SGF
- MAD
1 stop19h 36m
Multiple Airlines
Thu 4/163:55 pm
MAD
- SGF
1 stop25h 29m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$492
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/92:15 pm
MCI
- MAD
2 stops19h 05m
Delta
Tue 3/176:00 am
MAD
- MCI
2 stops20h 50m
Delta
Deal found 2/3![Delta logo]()
$499
Best flights from Missouri to MadridDiscover carefully curated flight deals from Missouri to Madrid that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 4, 2026.
Discover carefully curated flight deals from Missouri to Madrid that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 4, 2026.
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/39:10 am
MCI
- MAD
2 stops15h 50m
United Airlines
Tue 3/1012:40 pm
MAD
- MCI
2 stops31h 40m
United Airlines
Deal found 2/3![United Airlines logo]()
$475
This Finnair deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/27:05 am
MCI
- MAD
1 stop18h 05m
Multiple Airlines
Mon 3/1611:30 am
MAD
- MCI
1 stop16h 34m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$478
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:30 am
STL
- MAD
1 stop18h 30m
Delta
Wed 3/189:00 am
MAD
- STL
1 stop29h 44m
Delta
Deal found 2/2![Delta logo]()
$478
This KLM deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/166:59 pm
STL
- MAD
1 stop31h 06m
KLM
Wed 4/16:00 am
MAD
- STL
2 stops17h 32m
KLM
Deal found 2/4![KLM logo]()
$527
This oojo deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/82:33 pm
SGF
- MAD
2 stops22h 32m
British Airways
Thu 4/161:35 pm
MAD
- SGF
1 stop14h 27m
British Airways
Deal found 2/2![British Airways logo]()
$530
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/124:49 pm
SGF
- MAD
1 stop14h 36m
American Airlines
Thu 5/213:55 pm
MAD
- SGF
1 stop14h 37m
American Airlines
Deal found 2/3![American Airlines logo]()
$696
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/412:15 pm
STL
- MAD
2 stops21h 25m
United Airlines
Thu 3/1212:40 pm
MAD
- STL
2 stops35h 20m
United Airlines
Deal found 2/3![United Airlines logo]()
$480
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/95:54 am
MCI
- MAD
1 stop20h 11m
Delta
Wed 3/1810:05 am
MAD
- MCI
1 stop29h 20m
Delta
Deal found 2/3![Delta logo]()
$491
This Finnair deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/47:05 am
STL
- MAD
1 stop16h 15m
Multiple Airlines
Thu 3/1211:30 am
MAD
- STL
1 stop18h 28m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$491
This oojo deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/124:30 pm
STL
- MAD
1 stop14h 00m
British Airways
Mon 4/271:00 pm
MAD
- STL
1 stop16h 59m
British Airways
Deal found 2/2![British Airways logo]()
$539
This Finnair deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:19 am
SGF
- MAD
1 stop19h 36m
Multiple Airlines
Thu 4/163:55 pm
MAD
- SGF
1 stop25h 29m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$492
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/91:15 pm
MCI
- MAD
2 stops35h 45m
United Airlines
Mon 3/161:45 pm
MAD
- MCI
2 stops28h 34m
United Airlines
Deal found 2/3![United Airlines logo]()
$495
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1012:17 pm
MCI
- MAD
2 stops15h 58m
Delta
Wed 3/186:00 am
MAD
- MCI
2 stops16h 55m
Delta
Deal found 2/3![Delta logo]()
$505
This oojo deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/216:57 pm
STL
- MAD
1 stop28h 48m
British Airways
Mon 3/309:00 pm
MAD
- STL
2 stops33h 44m
British Airways
Deal found 2/2![British Airways logo]()
$543
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/88:00 am
MCI
- MAD
2 stops21h 45m
United Airlines
Mon 3/168:25 am
MAD
- MCI
2 stops33h 54m
United Airlines
Deal found 2/3![United Airlines logo]()
$501
This KLM deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/86:41 pm
MCI
- MAD
1 stop31h 24m
Multiple Airlines
Mon 3/169:00 am
MAD
- MCI
2 stops17h 50m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$501
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/88:00 am
SGF
- MAD
2 stops25h 45m
United Airlines
Thu 4/166:05 am
MAD
- SGF
2 stops22h 55m
United Airlines
Deal found 2/2![United Airlines logo]()
$502
This KLM deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1012:17 pm
MCI
- MAD
2 stops15h 58m
Multiple Airlines
Mon 3/169:00 am
MAD
- MCI
2 stops17h 50m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$506
This Delta deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/166:59 pm
STL
- MAD
1 stop31h 06m
Delta
Wed 4/12:35 pm
MAD
- STL
1 stop25h 09m
Delta
Deal found 2/4![Delta logo]()
$568
This KLM deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:05 am
SGF
- MAD
2 stops17h 15m
KLM
Thu 5/219:50 am
MAD
- SGF
1 stop15h 20m
KLM
Deal found 2/4![KLM logo]()
$701
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/74:28 pm
COU
- MAD
2 stops14h 02m
American Airlines
Thu 5/1411:35 am
MAD
- COU
1 stop16h 55m
American Airlines
Deal found 2/2![American Airlines logo]()
$718
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/118:00 am
MCI
- MAD
2 stops23h 15m
United Airlines
Mon 3/168:25 am
MAD
- MCI
2 stops33h 54m
United Airlines
Deal found 2/3![United Airlines logo]()
$512
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/118:00 am
MCI
- MAD
2 stops23h 15m
United Airlines
Tue 3/176:25 am
MAD
- MCI
2 stops21h 34m
United Airlines
Deal found 2/3![United Airlines logo]()
$514
This FlightHub deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/124:49 pm
SGF
- MAD
2 stops16h 01m
British Airways
Thu 5/213:55 pm
MAD
- SGF
1 stop14h 37m
British Airways
Deal found 2/3![British Airways logo]()
$727
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/117:40 am
STL
- MAD
2 stops22h 05m
United Airlines
Wed 3/185:55 am
MAD
- STL
1 stop15h 00m
United Airlines
Deal found 2/1![United Airlines logo]()
$578
This KLM deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:05 am
SGF
- MAD
2 stops17h 15m
Multiple Airlines
Thu 5/216:00 am
MAD
- SGF
2 stops19h 10m
Multiple Airlines
Deal found 2/4![Multiple Airlines logo]()
$710
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/185:00 am
STL
- MAD
2 stops24h 45m
United Airlines
Thu 3/266:25 am
MAD
- STL
2 stops20h 50m
United Airlines
Deal found 2/4![United Airlines logo]()
$588
This Finnair deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 am
COU
- MAD
1 stop18h 55m
Multiple Airlines
Thu 5/1411:35 am
MAD
- COU
1 stop16h 55m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$714
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/73:10 pm
COU
- MAD
2 stops32h 40m
United Airlines
Thu 5/146:05 am
MAD
- COU
2 stops22h 53m
United Airlines
Deal found 2/2![United Airlines logo]()
$650
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/258:00 am
COU
- MAD
2 stops18h 15m
United Airlines
Sun 3/15:55 am
MAD
- COU
2 stops22h 38m
United Airlines
Deal found 2/3![United Airlines logo]()
$682
Last-minute flights from Missouri to MadridDiscover last-minute flight deals from Missouri to Madrid. Data last updated February 4, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Madrid. Data last updated February 4, 2026 and is based on user searches.
This Flighttix deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:16 pm
MCI
- MAD
2 stops30h 44m
Virgin Atlantic
Mon 3/169:00 am
MAD
- MCI
2 stops19h 04m
Virgin Atlantic
Deal found 2/2![Virgin Atlantic logo]()
$464
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/21:23 pm
MCI
- MAD
1 stop12h 52m
KLM
Tue 3/176:00 am
MAD
- MCI
2 stops16h 55m
KLM
Deal found 2/2![KLM logo]()
$466
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/211:32 am
MCI
- MAD
2 stops14h 43m
United Airlines
Tue 3/1711:15 am
MAD
- MCI
2 stops18h 00m
United Airlines
Deal found 2/2![United Airlines logo]()
$478
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/39:10 am
MCI
- MAD
2 stops15h 50m
United Airlines
Tue 3/1012:40 pm
MAD
- MCI
2 stops31h 40m
United Airlines
Deal found 2/3![United Airlines logo]()
$475
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/411:25 am
STL
- MAD
2 stops22h 15m
United Airlines
Thu 3/1212:40 pm
MAD
- STL
2 stops32h 03m
United Airlines
Deal found 2/4![United Airlines logo]()
$480
This Cheapflightsfares deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/43:50 pm
STL
- MAD
1 stop21h 25m
Lufthansa
Thu 3/126:00 am
MAD
- STL
2 stops22h 59m
Lufthansa
Deal found 2/4![Lufthansa logo]()
$488
This Finnair deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/47:05 am
STL
- MAD
1 stop16h 15m
Multiple Airlines
Thu 3/1211:30 am
MAD
- STL
1 stop18h 28m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$491
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:30 am
STL
- MAD
1 stop18h 30m
Delta
Wed 3/189:00 am
MAD
- STL
1 stop29h 44m
Delta
Deal found 2/2![Delta logo]()
$478
This KLM deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/86:41 pm
MCI
- MAD
1 stop31h 24m
KLM
Tue 3/176:00 am
MAD
- MCI
2 stops16h 55m
KLM
Deal found 2/3![KLM logo]()
$500
This Finnair deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/96:28 am
MCI
- MAD
1 stop20h 22m
Multiple Airlines
Mon 3/1611:30 am
MAD
- MCI
1 stop19h 09m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$491
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/91:15 pm
MCI
- MAD
2 stops35h 45m
United Airlines
Mon 3/161:45 pm
MAD
- MCI
2 stops28h 34m
United Airlines
Deal found 2/3![United Airlines logo]()
$495
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/92:15 pm
MCI
- MAD
2 stops19h 05m
Delta
Tue 3/176:00 am
MAD
- MCI
2 stops20h 50m
Delta
Deal found 2/3![Delta logo]()
$499
One-way flights from Missouri to MadridSearch for one-way flight options from Missouri to Madrid. Find affordable one-way fares based on user searches. Data last updated February 4, 2026.
Search for one-way flight options from Missouri to Madrid. Find affordable one-way fares based on user searches. Data last updated February 4, 2026.
This Mytrip deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:00 am
MCI
- MAD
2 stops17h 50m
Air Canada
Deal found 2/3![Air Canada logo]()
$320
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1310:48 am
MCI
- MAD
1 stop14h 07m
American Airlines
Deal found 2/3![American Airlines logo]()
$321
This FlightHub deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/162:20 pm
STL
- MAD
2 stops33h 30m
Air Canada
Deal found 2/3![Air Canada logo]()
$330
This Expedia deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/178:02 pm
STL
- MAD
2 stops34h 23m
Iberia
Deal found 2/3![Iberia logo]()
$341
This Trip.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/179:40 pm
STL
- MAD
1 stop29h 00m
British Airways
Deal found 2/3![British Airways logo]()
$342
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/294:51 pm
STL
- MAD
3 stops47h 14m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$374
This KAYAK deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/216:14 am
STL
- MAD
2 stops21h 41m
Aer Lingus
Deal found 2/4![Aer Lingus logo]()
$380
This eDestinos deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/175:21 pm
STL
- MAD
2 stops37h 04m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$381
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2711:13 am
MCI
- MAD
3 stops47h 07m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$382
This Mytrip deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/279:55 am
MCI
- MAD
2 stops37h 55m
Air Canada
Deal found 2/3![Air Canada logo]()
$398
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/137:00 am
MCI
- MAD
3 stops51h 55m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$407
This Flysmarter deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flysmarter is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/276:05 am
MCI
- MAD
1 stop19h 55m
Lufthansa
Deal found 2/3![Lufthansa logo]()
$408
Find flight deals from Missouri to Madrid
Keep the following information in mind while searching for Missouri to Madrid flight deals. Data was last updated February 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $464 (Flighttix) |
One-way from | $320 (Mytrip) |
Popular in | June |
Cheapest in | November |
Average price | $689 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from Missouri to Madrid that are best for you.
Fly from
Missouri
Fly to
Madrid
Route
Depart
Return
Price
Kansas CityMadrid
MCI - MAD
MCIMAD
Kansas City
Tue 3/3
9:10 am-8:00 am
2 stops15h 50m
Madrid Barajas
Tue 3/10
12:40 pm-2:20 pm
2 stops31h 40m
$475
Kansas CityMadrid
MCI - MAD
MCIMAD
Kansas City
Mon 3/2
7:05 am-8:10 am
1 stop18h 05m
Madrid Barajas
Mon 3/16
11:30 am-10:04 pm
1 stop16h 34m
$478
St. LouisMadrid
STL - MAD
STLMAD
Lambert-St Louis
Thu 3/5
6:30 am-8:00 am
1 stop18h 30m
Madrid Barajas
Wed 3/18
9:00 am-8:44 am
1 stop29h 44m
$478
St. LouisMadrid
STL - MAD
STLMAD
Lambert-St Louis
Wed 3/4
12:15 pm-4:40 pm
2 stops21h 25m
Madrid Barajas
Thu 3/12
12:40 pm-6:00 pm
2 stops35h 20m
$480
Kansas CityMadrid
MCI - MAD
MCIMAD
Kansas City
Mon 3/9
5:54 am-8:05 am
1 stop20h 11m
Madrid Barajas
Wed 3/18
10:05 am-9:25 am
1 stop29h 20m
$491
St. LouisMadrid
STL - MAD
STLMAD
Lambert-St Louis
Wed 3/4
7:05 am-6:20 am
1 stop16h 15m
Madrid Barajas
Thu 3/12
11:30 am-11:58 pm
1 stop18h 28m
$491
SpringfieldMadrid
SGF - MAD
SGFMAD
Springfield-Branson
Wed 4/8
5:19 am-7:55 am
1 stop19h 36m
Madrid Barajas
Thu 4/16
3:55 pm-10:24 am
1 stop25h 29m
$492
Kansas CityMadrid
MCI - MAD
MCIMAD
Kansas City
Mon 3/9
1:15 pm-7:00 am
2 stops35h 45m
Madrid Barajas
Mon 3/16
1:45 pm-12:19 pm
2 stops28h 34m
$495
Kansas CityMadrid
MCI - MAD
MCIMAD
Kansas City
Sun 3/8
8:00 am-11:45 am
2 stops21h 45m
Madrid Barajas
Mon 3/16
8:25 am-12:19 pm
2 stops33h 54m
$501
Kansas CityMadrid
MCI - MAD
MCIMAD
Kansas City
Sun 3/8
6:41 pm-8:05 am
1 stop31h 24m
Madrid Barajas
Mon 3/16
9:00 am-8:50 pm
2 stops17h 50m
$501
Showing 1-10 of 47 results
Best time to book a flight from Missouri to Madrid
Have a flexible travel schedule? Discover the best time to fly to Madrid from Missouri with our price prediction graph.
MCI-MAD
STL-MAD
SGF-MAD
COU-MAD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Madrid
USMO-MAD
MCI-MAD
STL-MAD
SGF-MAD
COU-MAD
What is the cheapest month to book a flight from Missouri to Madrid?
Currently, March is the cheapest month in which you can book a flight from Missouri to Madrid (average of $440). Flying from Missouri to Madrid in June is currently the most expensive (average of $768). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Madrid. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Madrid?
Book flights to Madrid if you plan to visit one of these locationsGetafe
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Alternative routes for Missouri to Madrid
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Complete your trip
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Search flights from Missouri to Madrid by cabin class
Find flights from Missouri to Madrid, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Madrid
Explore flights to Madrid departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on February 4, 2026.
Missouri and Madrid flights
Browse other Missouri and Madrid flight options. Last updated on February 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Missouri to Madrid flights
Consider these flights traveling from Missouri to Madrid.
Top 10 airlines flying from Missouri to Madrid
Discover the top 10 airlines that operate flights from Missouri to Madrid. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$437 | Average$805 | FlexibilityNo cancel fee | On-time72% | |
| Cheapest$457 | Average$754 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$482 | Average$949 | FlexibilityNo cancel fee | On-time76% | |
| Cheapest$487 | Average$805 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$488 | Average$697 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$488 | Average$882 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$500 | Average$871 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$511 | Average$738 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$513 | Average$922 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$701 | Average$947 | FlexibilityNo cancel fee | On-time67% |