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$199+ Cheap flights from Key Largo, FL to Madrid, Spain (MAD)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/17. Fares are subject to change and may not be available on all flights or dates of travel.
MIA — MAD
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheapflights Tip: The best prices from Key Largo to Madrid Barajas are usually found in February or January, booked 72 days in advance, depart on a Wednesday or Tuesday and return on a Thursday

Cheap flight deals from Key Largo to Madrid

Keep the following information in mind while searching for Key Largo to Madrid flight deals. Data was last updated September 15, 2025.

Round-trip from

$402
(TAP AIR PORTUGAL)

One-way from

$199
(SmartFares)

Popular in

June

Cheapest in

February

Average price

$587
From Key Largo to Madrid Barajas
Search Deals
One-way flight from Key Largo to Madrid Barajas
Search Deals
Highest demand for flights based on searches. 25% potential increase in price ($226 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($31 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Key Largo to Madrid

Cheapest flights from Key Largo to Madrid
Explore the most affordable flight options available from Key Largo to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This TAP AIR PORTUGAL deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure TAP AIR PORTUGAL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3112:35 amMIA - MAD
1 stop14h 45mTAP AIR PORTUGAL
Wed 11/122:55 pmMAD - MIA
1 stop12h 55mTAP AIR PORTUGAL
Deal found 9/13$402
This eDestinos deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/89:45 pmMIA - MAD
1 stop12h 30mIberia
Tue 11/410:00 amMAD - MIA
Nonstop9h 55mIberia
Deal found 9/12$403
This Mytrip deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/275:35 pmMIA - MAD
1 stop18h 35mTAP AIR PORTUGAL
Tue 11/116:00 pmMAD - MIA
1 stop26h 50mTAP AIR PORTUGAL
Deal found 9/13$404
This Booking.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2710:45 pmMIA - MAD
Nonstop8h 20mAir Europa
Tue 11/113:25 pmMAD - MIA
Nonstop10h 05mAir Europa
Deal found 9/13$405
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1211:35 pmMIA - MAD
1 stop17h 55mTAP AIR PORTUGAL
Sat 11/229:10 pmMAD - MIA
1 stop23h 40mTAP AIR PORTUGAL
Deal found 9/14$407
This eDestinos deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/239:55 pmMIA - MAD
Nonstop8h 50mIberia
Sat 11/811:30 amMAD - MIA
Nonstop10h 15mIberia
Deal found 9/14$408
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/44:35 pmMIA - MAD
1 stop10h 55mTAP AIR PORTUGAL
Wed 11/1210:20 amMAD - MIA
1 stop17h 30mTAP AIR PORTUGAL
Deal found 9/12$409
This oojo deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/34:35 pmMIA - MAD
1 stop15h 30mTAP AIR PORTUGAL
Tue 11/189:10 pmMAD - MIA
1 stop23h 40mTAP AIR PORTUGAL
Deal found 9/13$411
This eDestinos deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/39:45 pmMIA - MAD
Nonstop8h 20mAir Europa
Sun 11/163:25 pmMAD - MIA
Nonstop10h 05mAir Europa
Deal found 9/14$412
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1611:50 pmMIA - MAD
1 stop11h 20mTAP AIR PORTUGAL
Sun 11/2310:20 amMAD - MIA
1 stop17h 45mTAP AIR PORTUGAL
Deal found 9/14$413

Cheapflights Fare Finder

 
Customize your flight search to find flights from Key Largo to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Key Largo to Madrid that are best for you.

Fly from

Key Largo

Fly to

Madrid

Route

Depart

Return

Price

MiamiMadrid

MIA - MAD

MIAMAD

Miami

Sun 11/23

7:00 am-4:10 pm

2 stops27h 10m

Madrid Barajas

Wed 12/3

5:00 pm-6:05 pm

2 stops31h 05m

$421

MiamiMadrid

MIA - MAD

MIAMAD

Miami

Mon 11/17

7:00 am-4:10 pm

2 stops27h 10m

Madrid Barajas

Sat 11/22

6:35 pm-6:05 pm

1 stop29h 30m

$424

MiamiMadrid

MIA - MAD

MIAMAD

Miami

Mon 10/27

4:30 pm-5:50 am

Nonstop8h 20m

Madrid Barajas

Tue 11/11

4:25 pm-8:45 pm

Nonstop10h 20m

$425

MiamiMadrid

MIA - MAD

MIAMAD

Miami

Wed 10/29

11:16 am-7:00 am

1 stop14h 44m

Madrid Barajas

Fri 11/7

10:00 am-6:33 pm

1 stop14h 33m

$438

MiamiMadrid

MIA - MAD

MIAMAD

Miami

Wed 2/11

3:35 pm-5:50 am

Nonstop8h 15m

Madrid Barajas

Mon 2/16

9:35 pm-3:20 pm

1 stop23h 45m

$443

MiamiMadrid

MIA - MAD

MIAMAD

Miami

Tue 1/13

12:10 pm-8:00 am

2 stops13h 50m

Madrid Barajas

Thu 1/29

10:00 am-12:57 am

2 stops20h 57m

$443

MiamiMadrid

MIA - MAD

MIAMAD

Miami

Tue 10/21

6:45 am-6:40 am

2 stops17h 55m

Madrid Barajas

Wed 11/19

5:55 am-2:40 pm

1 stop14h 45m

$450

MiamiMadrid

MIA - MAD

MIAMAD

Miami

Mon 10/27

4:42 pm-9:15 am

1 stop11h 33m

Madrid Barajas

Tue 11/11

6:00 am-2:40 pm

1 stop14h 40m

$450

MiamiMadrid

MIA - MAD

MIAMAD

Miami

Tue 10/21

8:45 am-9:00 am

2 stops18h 15m

Madrid Barajas

Wed 10/29

5:55 am-3:40 pm

1 stop14h 45m

$458

MiamiMadrid

MIA - MAD

MIAMAD

Miami

Mon 10/13

11:16 am-7:50 am

1 stop14h 34m

Madrid Barajas

Thu 10/23

6:00 am-8:00 pm

2 stops20h 00m

$462

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 22 results
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Best time to book a flight from Key Largo to Madrid

Have a flexible travel schedule? Discover the best time to fly to Madrid from Key Largo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key Largo to Madrid

How far ahead should I book a flight from Key Largo to Madrid?

Use this chart to determine the optimal time to book a round-trip flight from Key Largo to Madrid. Price data was last updated on September 12, 2025.

The best time to book flights from Key Largo to Madrid is 72 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Key Largo to Madrid?

Currently, November is the cheapest month in which you can book a flight from Key Largo to Madrid (average of $543). Flying from Key Largo to Madrid in June is currently the most expensive (average of $1,054). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from KE9 to MAD?

Find hourly flight availability from Key Largo to Madrid. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

When flying from Key Largo to Madrid, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What is the cheapest day to fly from Key Largo to Madrid?

Use this chart to determine the cheapest time to fly round-trip from Key Largo to Madrid. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Key Largo to Madrid flight should consider departing on Wednesday at noon when fares are most often at their lowest. Saturday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Key Largo to Madrid

Explore weekly flight availability from Key Largo to Madrid. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 15, 2025.

The most flights from KE9 to MAD are scheduled on a Tuesday (23 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (22 on average).

How much does it cost to fly round-trip from Key Largo to Madrid?

Reviews of airlines servicing Madrid

Get insights into the airlines that provide service to Madrid. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Madrid. Reviews last updated September 15, 2025.
Peruse reviews from past customers who have flown with American Airlines, TAP AIR PORTUGAL, and Air Europa from Key Largo to Madrid to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Comfort

7.2

Overall

7.2

Entertainment

6.9

Boarding

7.5

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Comfort

7.2

Overall

7.2

Entertainment

6.9

Boarding

7.5

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
TAP AIR PORTUGAL
7.1
Good
1,975 reviews
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Comfort

7.2

Overall

7.2

Entertainment

6.9

Boarding

7.5

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
Air Europa
7.0
Good
556 reviews
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Comfort

7.2

Overall

7.2

Entertainment

6.9

Boarding

7.5

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
Iberia
7.0
Good
2,924 reviews
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Comfort

7.2

Overall

7.2

Entertainment

6.9

Boarding

7.5

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
British Airways
6.7
Okay
7,361 reviews
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Comfort

7.2

Overall

7.2

Entertainment

6.9

Boarding

7.5

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.

Related info for your journey

Find useful and relevant information for your journey from Key Largo to Madrid. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Madrid from Key Largo?

    Located just 8.5 mi from the city center, Madrid Barajas is the airport most travelers will use when flying to Madrid from Key Largo. Booking flights from Key Largo to Barajas (MAD) should be relatively easy as there are 22 daily inbound flights from Key Largo from 23 different airlines.

  • How popular is this Key Largo to Madrid flight route?

    Within the past month, 282 users have taken a look at flights from Key Largo to Madrid Barajas.

  • How long is the flight from Key Largo to Madrid?

    For as low as $425, Scandinavian Airlines can have you in Madrid from Key Largo in 8h 20m. The distance between Key Largo and Madrid is about 4412 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most reliable airlines from Key Largo to Madrid?

    Consider Air Europa (92%), SAUDIA (92%) or Kenya Airways (92%) when booking your flight. These represent the most reliable airlines when flying from Key Largo to Madrid.

  • What are the cheapest flights from Key Largo to Madrid?

    On average you can expect to pay $1,318 for a flight from Key Largo to Madrid. The cheapest flight overall is $279 while the most popular route, (Miami - Madrid Barajas) is currently priced at $361.

  • Can I find deals for flights from Key Largo to Madrid that include hotel bookings?

    Yes. In addition to deals on Key Largo to Madrid flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key Largo to Madrid?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key Largo to Madrid.

  • Can I find deals for business class flights from Key Largo to Madrid?

    Yes. Cheapflights offers flight deals from Key Largo to Madrid by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key Largo to Madrid?

    Currently, November is the cheapest month in which you can book a flight from Key Largo to Madrid (average of $543). Flying from Key Largo to Madrid in June is currently the most expensive (average of $1,054). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Madrid?

Book flights to Madrid if you plan to visit one of these locations
Fuenlabrada
Getafe

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Top 10 airlines flying from Key Largo to Madrid

Discover the top 10 airlines that operate flights from Key Largo to Madrid. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$111Average$288FlexibilityNo cancel feeOn-time62%
SWISSCheapest$137Average$540FlexibilityNo cancel feeOn-time79%
AviancaCheapest$310Average$1,274FlexibilityNo cancel feeOn-time71%
ITA AirwaysCheapest$341Average$482FlexibilityNo cancel feeOn-time81%
TAP AIR PORTUGALCheapest$343Average$561FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$351Average$555FlexibilityNo cancel feeOn-time69%
KLMCheapest$364Average$588FlexibilityNo cancel feeOn-time75%
DeltaCheapest$367Average$574FlexibilityNo cancel feeOn-timeN/A
Air CanadaCheapest$378Average$547FlexibilityNo cancel feeOn-time67%
Virgin AtlanticCheapest$392Average$612FlexibilityNo cancel feeOn-time72%

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