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$319+ Cheap flights from Iowa to Madrid, Spain (MAD)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/31. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MAD
Nov 15 — Nov 221
Sat 11/15
Sat 11/22
1 adult, Economy
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Find flight deals from Iowa to Madrid

Cheapest flights from Iowa to Madrid
Explore the most affordable flight options available from Iowa to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 16, 2025.

This Flighttix deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2710:50 amDSM - MAD
1 stop15h 15mVirgin Atlantic
Wed 11/1211:15 amMAD - DSM
1 stop18h 18mVirgin Atlantic
Deal found 10/14$425
This lastminute.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2811:28 amDSM - MAD
1 stop13h 32mVirgin Atlantic
Fri 12/511:15 amMAD - DSM
2 stops41h 00mVirgin Atlantic
Deal found 10/14$454
This Ticket deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ticket is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/305:35 amDSM - MAD
1 stop20h 40mKLM
Sun 12/76:00 amMAD - DSM
2 stops18h 03mKLM
Deal found 10/16$460
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/95:35 amDSM - MAD
1 stop20h 40mDelta
Tue 11/186:00 amMAD - DSM
2 stops23h 33mDelta
Deal found 10/14$462
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/116:19 amOMA - MAD
2 stops18h 41mDelta
Wed 11/196:00 amMAD - OMA
2 stops21h 59mDelta
Deal found 10/14$466
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/85:15 pmDSM - MAD
1 stop33h 00mDelta
Tue 11/186:00 amMAD - DSM
2 stops23h 33mDelta
Deal found 10/14$467
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1011:26 amDSM - MAD
2 stops22h 14mUnited Airlines
Tue 11/181:35 pmMAD - DSM
2 stops38h 57mUnited Airlines
Deal found 10/13$474
This Flighttix deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/288:02 amDSM - MAD
2 stops16h 58mMultiple Airlines
Fri 12/51:45 pmMAD - DSM
2 stops34h 39mMultiple Airlines
Deal found 10/14$479
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/112:17 pmDSM - MAD
2 stops21h 53mDelta
Tue 11/186:00 amMAD - DSM
2 stops23h 33mDelta
Deal found 10/14$480
This Virgin Atlantic deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/305:54 amCID - MAD
1 stop20h 21mVirgin Atlantic
Sun 12/711:15 amMAD - CID
1 stop18h 21mVirgin Atlantic
Deal found 10/16$488
This Finnair deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/229:23 amOMA - MAD
1 stop15h 32mMultiple Airlines
Fri 10/311:15 pmMAD - OMA
1 stop13h 37mMultiple Airlines
Deal found 10/15$488
This KLM deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/305:54 amCID - MAD
1 stop20h 21mKLM
Sun 12/76:00 amMAD - CID
2 stops16h 45mKLM
Deal found 10/16$491

Cheap flight deals from Iowa to Madrid

Keep the following information in mind while searching for Iowa to Madrid flight deals. Data was last updated October 16, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$425
(Flighttix)

One-way from

$319
(Mytrip)

Popular in

June

Cheapest in

January

Average price

$844
Provider with most accurate pricing for Des Moines-Madrid Barajas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Madrid Barajas flights.
Search Deals
From Iowa to Madrid Barajas
Search Deals
One-way flight from Iowa to Madrid Barajas
Search Deals
Highest demand for flights based on searches. 30% potential increase in price ($436 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($57 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from Iowa to Madrid that are best for you.

Fly from

Iowa

Fly to

Madrid

Route

Depart

Return

Price

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Mon 10/27

10:00 am-8:05 am

2 stops16h 05m

Madrid Barajas

Wed 11/12

10:00 am-8:47 pm

2 stops17h 47m

$443

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Sun 11/9

6:17 am-9:15 am

2 stops19h 58m

Madrid Barajas

Tue 11/18

6:00 am-10:33 pm

2 stops23h 33m

$466

OmahaMadrid

OMA - MAD

OMAMAD

Omaha Eppley Airfield

Tue 11/11

6:19 am-8:00 am

2 stops18h 41m

Madrid Barajas

Wed 11/19

6:00 am-8:59 pm

2 stops21h 59m

$466

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Mon 11/10

11:26 am-4:40 pm

2 stops22h 14m

Madrid Barajas

Tue 11/18

1:35 pm-9:32 pm

2 stops38h 57m

$474

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Tue 11/11

1:05 pm-4:40 pm

2 stops20h 35m

Madrid Barajas

Tue 11/18

1:35 pm-9:32 pm

2 stops38h 57m

$474

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Wed 11/12

1:05 pm-4:40 pm

2 stops20h 35m

Madrid Barajas

Tue 11/18

1:35 pm-9:32 pm

2 stops38h 57m

$474

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Wed 11/12

10:21 am-5:40 pm

2 stops24h 19m

Madrid Barajas

Tue 11/18

6:00 am-10:33 pm

2 stops23h 33m

$481

Cedar RapidsMadrid

CID - MAD

CIDMAD

Cedar Rapids

Sun 11/30

5:54 am-9:15 am

1 stop20h 21m

Madrid Barajas

Sun 12/7

11:15 am-10:36 pm

1 stop18h 21m

$488

Cedar RapidsMadrid

CID - MAD

CIDMAD

Cedar Rapids

Sun 11/30

5:54 am-9:15 am

1 stop20h 21m

Madrid Barajas

Sun 12/7

6:00 am-3:45 pm

2 stops16h 45m

$491

OmahaMadrid

OMA - MAD

OMAMAD

Omaha Eppley Airfield

Thu 2/19

11:05 am-8:00 am

2 stops13h 55m

Madrid Barajas

Tue 2/24

11:15 am-9:21 pm

1 stop17h 06m

$493

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/13

Showing 1-10 of 41 results
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Best time to book a flight from Iowa to Madrid

Have a flexible travel schedule? Discover the best time to fly to Madrid from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Madrid

What is the cheapest month to book a flight from Iowa to Madrid?

Currently, September is the cheapest month in which you can book a flight from Iowa to Madrid (average of $454). Flying from Iowa to Madrid in July is currently the most expensive (average of $1,131). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to MAD?

Find hourly flight availability from Iowa to Madrid. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 16, 2025.

One of the essential ways to save on airfare from Iowa to Madrid is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 23% on airfare.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Madrid. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Madrid from Iowa?

    Located just 8.5 mi from the city center, Madrid Barajas (MAD) is the airport most travelers will use when flying to Madrid from Iowa.

  • How long is the flight from Iowa to Madrid?

    Departing from Iowa to Madrid will take you 16h 05m. Iowa and Madrid are separated by a distance of 4457 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Iowa to Madrid one-way?

    One-way options have recently been found by users for as low as $397 on Air Canada. Other airlines that offer cheap prices include Lufthansa from $403 and United Airlines from $405 one-way.

  • What are the most popular routes from Iowa to Madrid?

    Most travelers choose Omaha Eppley Airfield - Madrid Barajas, Des Moines - Madrid Barajas or Cedar Rapids - Madrid Barajas when deciding on the best route from Iowa to Madrid.

  • Can I find deals for flights from Iowa to Madrid that include hotel bookings?

    Yes. In addition to deals on Iowa to Madrid flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Madrid?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Madrid.

  • Can I find deals for business class flights from Iowa to Madrid?

    Yes. Cheapflights offers flight deals from Iowa to Madrid by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Madrid?

    Currently, September is the cheapest month in which you can book a flight from Iowa to Madrid (average of $454). Flying from Iowa to Madrid in July is currently the most expensive (average of $1,131). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Madrid?

Book flights to Madrid if you plan to visit one of these locations
Fuenlabrada
Getafe

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Top 3 airlines flying from Iowa to Madrid

Discover the top 3 airlines that operate flights from Iowa to Madrid. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$549Average$1,045FlexibilityNo cancel feeOn-time71%
DeltaCheapest$644Average$735FlexibilityNo cancel feeOn-timeN/A
IberiaCheapest$686Average$1,340FlexibilityNo cancel feeOn-time77%

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