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$416+ Cheap flights from Midway (MDW) to Lyon (LYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/12. Fares are subject to change and may not be available on all flights or dates of travel.
MDW — LYS
Dec 5 — Dec 121
Fri 12/5
Fri 12/12
1 adult, Economy
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Find flight deals from Midway to Lyon

Cheapest flights from Midway to Lyon
Explore the most affordable flight options available from Midway to Lyon. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2025.

This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/131:15 pmMDW - LYS
2 stops14h 20mDelta
Wed 11/262:10 pmLYS - MDW
2 stops16h 30mDelta
Deal found 11/4$745
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/191:15 pmMDW - LYS
2 stops14h 20mDelta
Sun 11/236:40 amLYS - MDW
2 stops18h 38mDelta
Deal found 11/3$836
This Mytrip deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1911:00 amMDW - LYS
3 stops17h 05mMultiple Airlines
Sun 11/231:55 pmLYS - MDW
2 stops27h 10mMultiple Airlines
Deal found 11/3$887
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/181:14 pmMDW - LYS
2 stops17h 11mDelta
Thu 12/256:55 amLYS - MDW
2 stops17h 24mDelta
Deal found 11/3$1,284
This Mytrip deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2011:00 amMDW - LYS
2 stops14h 15mMultiple Airlines
Sat 12/2710:00 amLYS - MDW
2 stops31h 05mMultiple Airlines
Deal found 11/4$1,813
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/289:29 amMDW - LYS
2 stops18h 06mDelta
Fri 1/26:40 amLYS - MDW
2 stops17h 46mDelta
Deal found 11/3$2,217
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:08 pmMDW - LYS
2 stops16h 27mDelta
Fri 1/26:40 amLYS - MDW
2 stops17h 39mDelta
Deal found 11/4$2,246
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/219:29 amMDW - LYS
2 stops20h 56mDelta
Fri 1/26:40 amLYS - MDW
2 stops17h 46mDelta
Deal found 11/3$2,397
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:08 pmMDW - LYS
2 stops12h 42mDelta
Fri 1/26:40 amLYS - MDW
2 stops17h 39mDelta
Deal found 11/4$2,571

Cheap flight deals from Midway to Lyon

Discover tips and strategies to find the most affordable flight options for your journey from Midway (MDW) to Lyon (LYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 5, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$809
(Delta)

One-way from

$416
(Kiwi.com)

Popular in

May

Cheapest in

January
Provider with most accurate pricing for Chicago Midway-Lyon-Saint Exupéry flight deals.
Search Deals
Provider most trusted by Cheapflights users for Chicago Midway-Lyon-Saint Exupéry flights.
Search Deals
From Chicago Midway to Lyon-Saint Exupéry
Search Deals
One-way flight from Chicago Midway to Lyon-Saint Exupéry
Search Deals
Highest demand for flights based on searches. 20% potential increase in price ($243 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($28 potential savings vs. average RT price).
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Midway to Lyon that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 5, 2025.
Use the filters below to find and compare flights from Chicago Midway Airport to Lyon that are best for you.

Fly from

Midway

Fly to

Lyon

Route

Depart

Return

Price

ChicagoLyon

MDW - LYS

MDWLYS

Chicago Midway

Fri 4/3

9:30 am-5:50 pm

2 stops25h 20m

Lyon-Saint Exupéry

Tue 4/7

9:55 am-6:08 pm

2 stops15h 13m

$809

ChicagoLyon

MDW - LYS

MDWLYS

Chicago Midway

Wed 11/19

1:15 pm-10:35 am

2 stops14h 20m

Lyon-Saint Exupéry

Sun 11/23

6:40 am-6:18 pm

2 stops18h 38m

$836

ChicagoLyon

MDW - LYS

MDWLYS

Chicago Midway

Wed 11/19

11:00 am-11:05 am

3 stops17h 05m

Lyon-Saint Exupéry

Sun 11/23

1:55 pm-10:05 am

2 stops27h 10m

$887

ChicagoLyon

MDW - LYS

MDWLYS

Chicago Midway

Fri 3/20

5:59 pm-2:05 pm

2 stops14h 06m

Lyon-Saint Exupéry

Sun 3/29

6:15 am-6:34 pm

2 stops19h 19m

$1,280

ChicagoLyon

MDW - LYS

MDWLYS

Chicago Midway

Thu 12/18

1:14 pm-1:25 pm

2 stops17h 11m

Lyon-Saint Exupéry

Thu 12/25

6:55 am-5:19 pm

2 stops17h 24m

$1,284

ChicagoLyon

MDW - LYS

MDWLYS

Chicago Midway

Sat 12/20

11:00 am-8:15 am

2 stops14h 15m

Lyon-Saint Exupéry

Sat 12/27

10:00 am-10:05 am

2 stops31h 05m

$1,813

ChicagoLyon

MDW - LYS

MDWLYS

Chicago Midway

Sun 12/28

9:29 am-10:35 am

2 stops18h 06m

Lyon-Saint Exupéry

Fri 1/2

6:40 am-5:26 pm

2 stops17h 46m

$2,217

ChicagoLyon

MDW - LYS

MDWLYS

Chicago Midway

Fri 12/26

6:08 pm-5:35 pm

2 stops16h 27m

Lyon-Saint Exupéry

Fri 1/2

6:40 am-5:19 pm

2 stops17h 39m

$2,246

ChicagoLyon

MDW - LYS

MDWLYS

Chicago Midway

Fri 12/12

8:42 pm-9:40 am

3 stops53h 58m

$416

ChicagoLyon

MDW - LYS

MDWLYS

Chicago Midway

Sun 12/7

12:50 pm-11:05 am

2 stops15h 15m

$562

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/3

Showing 1-10 of 15 results
1
2
  • Most accurate provider: When it comes to deals on Chicago Midway Airport-Lyon flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Chicago Midway Airport-Lyon flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Chicago Midway Airport-Lyon flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Chicago Midway Airport-Lyon flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago Midway Airport-Lyon flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Midway to Lyon

Have a flexible travel schedule? Discover the best time to fly to Lyon from Midway with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Midway to Lyon. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Lyon from Chicago Midway?

    Lyon-Saint Exupéry (LYS), located 12.5 mi from the city center, is the airport you fly into when you book flights from Chicago Midway to Lyon. 0 airlines have flights to Lyon-Saint Exupéry from Chicago Midway on a regular basis. Booking flights from Chicago Midway to Lyon-Saint Exupéry should not be difficult; the airport handles an average of 0 inbound flights from Chicago Midway per day.

  • How long is the flight from Chicago Midway Airport to Lyon?

    A quick flight from Chicago Midway Airport to Lyon can take about 25h 20m. Delta provides one of the quickest options available for as low as $809. There are 4361 mi between Chicago Midway Airport and Lyon.

  • Can I find deals for flights from Midway to Lyon that include hotel bookings?

    Yes. In addition to deals on Midway to Lyon flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Midway to Lyon?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Midway to Lyon.

  • Can I find deals for business class flights from Midway to Lyon?

    Yes. Cheapflights offers flight deals from Midway to Lyon by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Lyon?

Book flights to Lyon if you plan to visit one of these locations
Annemasse
Huez

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Alternative routes for Midway to Lyon

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