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$346+ Cheap flights from Midway (MDW) to Lyon (LYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel.
MDW — LYS
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
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Find flight deals from Midway to Lyon

Cheapest flights from Midway to Lyon
Explore the most affordable flight options available from Midway to Lyon. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/285:34 pmMDW - LYS
2 stops17h 01mDelta
Thu 12/116:40 amLYS - MDW
2 stops16h 38mDelta
Deal found 11/11$1,079
This Mytrip deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2611:00 amMDW - LYS
2 stops17h 05mMultiple Airlines
Fri 1/26:25 amLYS - MDW
3 stops34h 40mMultiple Airlines
Deal found 11/11$2,173
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/161:15 pmMDW - LYS
2 stops14h 50mDelta
Sat 11/226:40 amLYS - MDW
2 stops18h 28mDelta
Deal found 11/11$2,399
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2611:48 amMDW - LYS
2 stops16h 17mDelta
Fri 1/26:40 amLYS - MDW
2 stops17h 39mDelta
Deal found 11/11$3,059
This Delta deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2811:48 amMDW - LYS
2 stops15h 47mDelta
Sun 1/46:40 amLYS - MDW
2 stops17h 39mDelta
Deal found 11/12$3,321
This Delta deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/209:29 amMDW - LYS
2 stops18h 21mDelta
Fri 1/26:40 amLYS - MDW
2 stops17h 39mDelta
Deal found 11/12$3,639
This Delta deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1910:49 amMDW - LYS
2 stops15h 41mDelta
Fri 1/26:40 amLYS - MDW
2 stops17h 39mDelta
Deal found 11/12$4,150
This KAYAK deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/71:50 pmMDW - LYS
2 stops14h 15mDelta
Thu 12/116:40 amLYS - MDW
2 stops18h 38mDelta
Deal found 11/12$9,018

Cheap flight deals from Midway to Lyon

Discover tips and strategies to find the most affordable flight options for your journey from Midway (MDW) to Lyon (LYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 13, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$1,079
(Delta)

One-way from

$346
(Kiwi.com)

Popular in

May

Cheapest in

February
Provider with most accurate pricing for Chicago Midway-Lyon-Saint Exupéry flight deals.
Search Deals
Provider most trusted by Cheapflights users for Chicago Midway-Lyon-Saint Exupéry flights.
Search Deals
From Chicago Midway to Lyon-Saint Exupéry
Search Deals
One-way flight from Chicago Midway to Lyon-Saint Exupéry
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($217 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($25 potential savings vs. average RT price).
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Midway to Lyon that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Chicago Midway Airport to Lyon that are best for you.

Fly from

Midway

Fly to

Lyon

Route

Depart

Return

Price

ChicagoLyon

MDW - LYS

MDWLYS

Chicago Midway

Fri 11/28

5:34 pm-5:35 pm

2 stops17h 01m

Lyon-Saint Exupéry

Thu 12/11

6:40 am-4:18 pm

2 stops16h 38m

$1,079

ChicagoLyon

MDW - LYS

MDWLYS

Chicago Midway

Thu 4/2

5:59 pm-5:50 pm

2 stops16h 51m

Lyon-Saint Exupéry

Fri 4/10

6:15 am-6:08 pm

2 stops18h 53m

$1,158

ChicagoLyon

MDW - LYS

MDWLYS

Chicago Midway

Fri 4/3

5:59 pm-1:45 pm

2 stops12h 46m

Lyon-Saint Exupéry

Tue 4/7

9:55 am-6:34 pm

2 stops39h 39m

$1,307

ChicagoLyon

MDW - LYS

MDWLYS

Chicago Midway

Fri 4/3

5:59 pm-1:45 pm

2 stops12h 46m

Lyon-Saint Exupéry

Sat 4/11

6:15 am-6:34 pm

2 stops19h 19m

$1,363

ChicagoLyon

MDW - LYS

MDWLYS

Chicago Midway

Sun 1/4

6:08 pm-5:35 pm

2 stops16h 27m

Lyon-Saint Exupéry

Sun 1/11

6:40 am-5:37 pm

2 stops17h 57m

$1,554

ChicagoLyon

MDW - LYS

MDWLYS

Chicago Midway

Fri 12/26

11:48 am-11:05 am

2 stops16h 17m

Lyon-Saint Exupéry

Fri 1/2

6:40 am-5:19 pm

2 stops17h 39m

$3,059

ChicagoLyon

MDW - LYS

MDWLYS

Chicago Midway

Sun 12/28

11:48 am-10:35 am

2 stops15h 47m

Lyon-Saint Exupéry

Sun 1/4

6:40 am-5:19 pm

2 stops17h 39m

$3,321

ChicagoLyon

MDW - LYS

MDWLYS

Chicago Midway

Sat 12/20

9:29 am-10:50 am

2 stops18h 21m

Lyon-Saint Exupéry

Fri 1/2

6:40 am-5:19 pm

2 stops17h 39m

$3,639

ChicagoLyon

MDW - LYS

MDWLYS

Chicago Midway

Thu 12/4

7:44 am-8:45 pm

3 stops30h 01m

$346

ChicagoLyon

MDW - LYS

MDWLYS

Chicago Midway

Sun 1/4

10:50 pm-6:05 pm

3 stops36h 15m

$564

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/11

Showing 1-10 of 11 results
1
2
  • Most accurate provider: When it comes to deals on Chicago Midway Airport-Lyon flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Chicago Midway Airport-Lyon flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Chicago Midway Airport-Lyon flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Chicago Midway Airport-Lyon flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago Midway Airport-Lyon flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Midway to Lyon

Have a flexible travel schedule? Discover the best time to fly to Lyon from Midway with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Midway to Lyon. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Lyon from Chicago Midway?

    Lyon-Saint Exupéry (LYS), located 12.5 mi from the city center, is the airport you fly into when you book flights from Chicago Midway to Lyon. 0 airlines have flights to Lyon-Saint Exupéry from Chicago Midway on a regular basis. Booking flights from Chicago Midway to Lyon-Saint Exupéry should not be difficult; the airport handles an average of 0 inbound flights from Chicago Midway per day.

  • How long is the flight from Chicago Midway Airport to Lyon?

    A quick flight from Chicago Midway Airport to Lyon can take about 17h 01m. Delta provides one of the quickest options available for as low as $1,079. There are 4361 mi between Chicago Midway Airport and Lyon.

  • Can I find deals for flights from Midway to Lyon that include hotel bookings?

    Yes. In addition to deals on Midway to Lyon flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Midway to Lyon?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Midway to Lyon.

  • Can I find deals for business class flights from Midway to Lyon?

    Yes. Cheapflights offers flight deals from Midway to Lyon by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Lyon?

Book flights to Lyon if you plan to visit one of these locations
Annemasse
Huez

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