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$332+ Cheap flights from Midway (MDW) to Lyon (LYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/28. Fares are subject to change and may not be available on all flights or dates of travel.
MDW — LYS
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Midway to Lyon

Discover tips and strategies to find the most affordable flight options for your journey from Midway (MDW) to Lyon (LYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$720
(Delta)

One-way from

$332
(Kiwi.com)

Popular in

May

Cheapest in

January

Average price

$831
From Chicago Midway to Lyon-Saint Exupéry
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One-way flight from Chicago Midway to Lyon-Saint Exupéry
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Highest demand for flights based on searches. 10% potential increase in price ($104 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($26 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Midway to Lyon

Cheapest flights from Midway to Lyon
Explore the most affordable flight options available from Midway to Lyon. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/812:48 pmMDW - LYS
2 stops15h 27mDelta
Wed 10/2910:25 amLYS - MDW
2 stops17h 49mDelta
Deal found 9/16$720
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/812:48 pmMDW - LYS
2 stops15h 27mDelta
Wed 10/1510:20 amLYS - MDW
2 stops18h 54mDelta
Deal found 9/14$831
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/311:08 pmMDW - LYS
2 stops15h 27mDelta
Fri 11/76:40 amLYS - MDW
2 stops18h 03mDelta
Deal found 9/16$857
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/151:50 pmMDW - LYS
2 stops16h 35mDelta
Mon 12/226:55 amLYS - MDW
2 stops17h 25mDelta
Deal found 9/15$991
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/161:14 pmMDW - LYS
2 stops17h 11mDelta
Tue 12/236:40 amLYS - MDW
2 stops17h 39mDelta
Deal found 9/15$1,008
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/141:14 pmMDW - LYS
2 stops17h 51mDelta
Sun 12/216:55 amLYS - MDW
2 stops17h 24mDelta
Deal found 9/15$1,108
This Mytrip deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/289:35 amMDW - LYS
2 stops20h 00mMultiple Airlines
Wed 10/12:05 pmLYS - MDW
3 stops34h 30mMultiple Airlines
Deal found 9/15$1,538
This Mytrip deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/279:35 amMDW - LYS
2 stops20h 00mMultiple Airlines
Tue 9/302:05 pmLYS - MDW
2 stops33h 19mMultiple Airlines
Deal found 9/14$1,761

Cheapflights Fare Finder

 
Customize your flight search to find flights from Midway to Lyon that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Chicago Midway Airport to Lyon that are best for you.

Fly from

Midway

Fly to

Lyon

Route

Depart

Return

Price

ChicagoLyon

MDW - LYS

MDWLYS

Chicago Midway

Wed 10/8

12:48 pm-11:15 am

2 stops15h 27m

Lyon-Saint Exupéry

Wed 10/29

10:25 am-10:14 pm

2 stops17h 49m

$720

ChicagoLyon

MDW - LYS

MDWLYS

Chicago Midway

Wed 10/8

12:48 pm-11:15 am

2 stops15h 27m

Lyon-Saint Exupéry

Wed 10/15

10:20 am-10:14 pm

2 stops18h 54m

$831

ChicagoLyon

MDW - LYS

MDWLYS

Chicago Midway

Mon 12/15

1:50 pm-1:25 pm

2 stops16h 35m

Lyon-Saint Exupéry

Mon 12/22

6:55 am-5:20 pm

2 stops17h 25m

$991

ChicagoLyon

MDW - LYS

MDWLYS

Chicago Midway

Tue 12/16

1:14 pm-1:25 pm

2 stops17h 11m

Lyon-Saint Exupéry

Tue 12/23

6:40 am-5:19 pm

2 stops17h 39m

$1,008

ChicagoLyon

MDW - LYS

MDWLYS

Chicago Midway

Sun 12/14

1:14 pm-2:05 pm

2 stops17h 51m

Lyon-Saint Exupéry

Sun 12/21

6:55 am-5:19 pm

2 stops17h 24m

$1,108

ChicagoLyon

MDW - LYS

MDWLYS

Chicago Midway

Sun 9/28

9:35 am-12:35 pm

2 stops20h 00m

Lyon-Saint Exupéry

Wed 10/1

2:05 pm-5:35 pm

3 stops34h 30m

$1,538

ChicagoLyon

MDW - LYS

MDWLYS

Chicago Midway

Sat 9/27

9:35 am-12:35 pm

2 stops20h 00m

Lyon-Saint Exupéry

Tue 9/30

2:05 pm-4:24 pm

2 stops33h 19m

$1,761

ChicagoLyon

MDW - LYS

MDWLYS

Chicago Midway

Sun 9/28

6:30 am-10:55 am

3 stops45h 25m

$332

ChicagoLyon

MDW - LYS

MDWLYS

Chicago Midway

Tue 1/6

5:25 pm-5:35 pm

2 stops17h 10m

$487

ChicagoLyon

MDW - LYS

MDWLYS

Chicago Midway

Tue 1/6

11:00 am-11:10 am

3 stops17h 10m

$1,063

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 11 results
1
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Best time to book a flight from Midway to Lyon

Have a flexible travel schedule? Discover the best time to fly to Lyon from Midway with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Midway to Lyon. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Lyon from Chicago Midway?

    Lyon-Saint Exupéry (LYS), located 12.5 mi from the city center, is the airport you fly into when you book flights from Chicago Midway to Lyon. 0 airlines have flights to Lyon-Saint Exupéry from Chicago Midway on a regular basis. Booking flights from Chicago Midway to Lyon-Saint Exupéry should not be difficult; the airport handles an average of 0 inbound flights from Chicago Midway per day.

  • How long is the flight from Chicago Midway Airport to Lyon?

    A quick flight from Chicago Midway Airport to Lyon can take about 15h 27m. Delta provides one of the quickest options available for as low as $720. There are 4361 mi between Chicago Midway Airport and Lyon.

  • Can I find deals for flights from Midway to Lyon that include hotel bookings?

    Yes. In addition to deals on Midway to Lyon flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Midway to Lyon?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Midway to Lyon.

  • Can I find deals for business class flights from Midway to Lyon?

    Yes. Cheapflights offers flight deals from Midway to Lyon by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago Midway Airport to Lyon?

    Currently, November is the cheapest month in which you can book a flight from Chicago Midway Airport to Lyon (average of $703). Flying from Chicago Midway Airport to Lyon in June is currently the most expensive (average of $1,199). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Lyon?

Book flights to Lyon if you plan to visit one of these locations
Annemasse
Huez

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