$229+ Cheap flights from Missoula to Louisville (MSO - SDF)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/13. Fares are subject to change and may not be available on all flights or dates of travel.
MSO — SDF
Oct 9 — Oct 161
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Missoula to Louisville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missoula to Louisville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Missoula to LouisvilleExplore the most affordable flight options available from Missoula to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
Explore the most affordable flight options available from Missoula to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/301:48 pm -
1 stop5h 47m
Mon 11/26:21 am -
1 stop8h 15m
Deal found 9/5![American Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:15 am -
1 stop6h 02m
Tue 12/89:00 am -
1 stop6h 27m
Deal found 9/8![United Airlines logo]()
$459
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:15 am -
1 stop6h 02m
Wed 12/93:20 pm -
1 stop8h 06m
Deal found 9/6![United Airlines logo]()
$479
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/221:05 pm -
2 stops18h 27m
Sun 10/256:29 am -
1 stop8h 06m
Deal found 9/8![American Airlines logo]()
$681
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/257:00 am -
1 stop8h 40m
Mon 12/283:36 pm -
1 stop7h 11m
Deal found 9/5![American Airlines logo]()
$690
Best flights from Missoula to LouisvilleDiscover carefully curated flight deals from Missoula to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
Discover carefully curated flight deals from Missoula to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:15 am -
1 stop6h 02m
Tue 12/89:00 am -
1 stop6h 27m
Deal found 9/8![United Airlines logo]()
$459
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:30 am -
2 stops11h 40m
Mon 11/21:59 pm -
2 stops10h 52m
Deal found 9/5![Delta logo]()
$479
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:15 am -
1 stop6h 02m
Wed 12/93:20 pm -
1 stop8h 06m
Deal found 9/5![United Airlines logo]()
$479
Last-minute flights from Missoula to LouisvilleDiscover last-minute flight deals from Missoula to Louisville. Data last updated September 9, 2026 and is based on user searches.
Discover last-minute flight deals from Missoula to Louisville. Data last updated September 9, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/133:35 pm -
1 stop5h 15m
Sat 9/195:30 pm -
2 stops8h 12m
Deal found 9/9![Delta logo]()
$834
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/132:40 pm -
1 stop5h 49m
Sat 9/198:00 am -
1 stop7h 38m
Deal found 9/5![United Airlines logo]()
$847
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:00 am -
2 stops13h 29m
Wed 9/168:00 am -
1 stop7h 38m
Deal found 9/8![United Airlines logo]()
$746
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/221:05 pm -
2 stops18h 27m
Sun 10/256:29 am -
1 stop8h 06m
Deal found 9/8![American Airlines logo]()
$681
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:15 am -
2 stops15h 26m
Sun 10/255:10 am -
2 stops10h 21m
Deal found 9/8![United Airlines logo]()
$744
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/301:48 pm -
1 stop5h 47m
Mon 11/26:21 am -
1 stop8h 15m
Deal found 9/5![American Airlines logo]()
$359
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:30 am -
2 stops11h 40m
Mon 11/21:59 pm -
2 stops10h 52m
Deal found 9/5![Delta logo]()
$479
One-way flights from Missoula to LouisvilleSearch for one-way flight options from Missoula to Louisville. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
Search for one-way flight options from Missoula to Louisville. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1310:14 am -
2 stops31h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$229
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/131:06 pm -
1 stop6h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![American Airlines logo]()
$261
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:38 pm -
2 stops12h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Delta logo]()
$276
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/146:28 pm -
3 stops44h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$313
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:50 am -
1 stop7h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![American Airlines logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/124:13 pm -
3 stops17h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$598
Find flight deals from Missoula to Louisville
Discover tips and strategies to find the most affordable flight options for your journey from Missoula (MSO) to Louisville (SDF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $359 (American Airlines) |
One-way from | $229 (Kiwi.com) |
Popular in | July |
Cheapest in | November |
Average price | $632 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missoula to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
Use the filters below to find and compare flights from Missoula to Louisville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MissoulaLouisville
MSO Missoula Johnson-Bell Field - SDF Louisville Intl
MSOSDF
Missoula Johnson-Bell Field
Mon 12/14
6:25 pm-9:08 am
2 stops12h 43m
Louisville Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$276
MissoulaLouisville
MSO Missoula Johnson-Bell Field - SDF Louisville Intl
MSOSDF
Missoula Johnson-Bell Field
Mon 12/14
6:28 pm-4:32 pm
3 stops44h 04m
Louisville Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$313
Quickest round-trip
MissoulaLouisville
MSO Missoula Johnson-Bell Field - SDF Louisville Intl
MSOSDF
Missoula Johnson-Bell Field
Sat 12/12
6:50 am-4:36 pm
1 stop7h 46m
Louisville Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$316
MissoulaLouisville
MSO Missoula Johnson-Bell Field - SDF Louisville Intl
MSOSDF
Missoula Johnson-Bell Field
Mon 12/14
6:50 am-6:09 pm
1 stop9h 19m
Louisville Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$316
MissoulaLouisville
MSO Missoula Johnson-Bell Field - SDF Louisville Intl
MSOSDF
Missoula Johnson-Bell Field
Sun 12/13
10:14 am-10:59 am
3 stops22h 45m
Louisville Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$378
MissoulaLouisville
MSO Missoula Johnson-Bell Field - SDF Louisville Intl
MSOSDF
Missoula Johnson-Bell Field
Sat 12/5
6:15 am-2:17 pm
1 stop6h 02m
Louisville Intl
Tue 12/8
9:00 am-1:27 pm
1 stop6h 27m
$459
MissoulaLouisville
MSO Missoula Johnson-Bell Field - SDF Louisville Intl
MSOSDF
Missoula Johnson-Bell Field
Fri 10/30
5:30 am-7:10 pm
2 stops11h 40m
Louisville Intl
Mon 11/2
1:59 pm-10:51 pm
2 stops10h 52m
$479
MissoulaLouisville
MSO Missoula Johnson-Bell Field - SDF Louisville Intl
MSOSDF
Missoula Johnson-Bell Field
Sat 12/5
6:15 am-2:17 pm
1 stop6h 02m
Louisville Intl
Wed 12/9
3:20 pm-9:26 pm
1 stop8h 06m
$479
Sorted by cheapest first
- Most accurate provider: When it comes to deals on Missoula-Louisville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Missoula-Louisville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Missoula-Louisville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Missoula-Louisville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Missoula-Louisville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Missoula to Louisville
Have a flexible travel schedule? Discover the best time to fly to Louisville from Missoula with our price prediction graph.
MSO-SDF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Louisville
Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated September 9, 2026.
Read through reviews of airlines operating flights from Missoula to Louisville, such as United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
6.6
Comfort
7.3
Overall
7.4
Crew
8.1
Boarding
7.7
Entertainment
7.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Food
6.6
Comfort
7.3
Overall
7.4
Crew
8.1
Boarding
7.7
Entertainment
7.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Related info for your journey
Find useful and relevant information for your journey from Missoula to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Louisville?
Book flights to Louisville if you plan to visit one of these locationsShepherdsville
Elizabethtown
Jeffersonville
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Louisville flight routes
Other flight options
Other flights from Missoula
Popular flights
Alternative routes for Missoula to Louisville
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Louisville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missoula to Louisville by cabin class
Find flights from Missoula to Louisville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Louisville
Explore flights to Louisville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 9, 2026.
Missoula and Louisville flights
Browse other Missoula and Louisville flight options. Last updated on September 9, 2026.
Other flights from Missoula
Browse through other flights departing from Missoula. Flights are based on user searches made on Cheapflights and were last updated on September 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Missoula to Louisville
Discover the top airline that operate flights from Missoula to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$288 | Average$473 | FlexibilityNo cancel fee | On-time69% |