$156+ Cheap flights from Roanoke (ROA) to Louisiana
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/18. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — MSY
Jul 11 — Jul 181
Round-trip
1 adult, Economy
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Cheapest flights from Roanoke to LouisianaExplore the most affordable flight options available from Roanoke to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 11, 2026.
Explore the most affordable flight options available from Roanoke to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 11, 2026.
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/105:00 am
ROA
- MSY
1 stop4h 38m
American Airlines
Mon 7/131:50 pm
MSY
- ROA
1 stop7h 28m
American Airlines
Deal found 6/10![American Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/48:10 am
ROA
- MSY
2 stops9h 57m
American Airlines
Fri 7/106:10 am
MSY
- ROA
1 stop7h 14m
American Airlines
Deal found 6/10![American Airlines logo]()
$314
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/97:50 pm
ROA
- MSY
1 stop4h 30m
Delta
Sat 9/127:30 am
MSY
- ROA
1 stop6h 11m
Delta
Deal found 6/8![Delta logo]()
$315
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:00 am
ROA
- MSY
1 stop4h 29m
Delta
Tue 7/147:28 am
MSY
- ROA
1 stop6h 19m
Delta
Deal found 6/8![Delta logo]()
$317
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:00 am
ROA
- MSY
1 stop4h 29m
Delta
Mon 7/135:02 pm
MSY
- ROA
1 stop6h 23m
Delta
Deal found 6/8![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/223:00 pm
ROA
- MSY
1 stop6h 34m
United Airlines
Wed 8/265:05 am
MSY
- ROA
2 stops8h 13m
United Airlines
Deal found 6/9![United Airlines logo]()
$320
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/94:48 pm
ROA
- MSY
2 stops8h 10m
American Airlines
Mon 7/131:50 pm
MSY
- ROA
1 stop7h 28m
American Airlines
Deal found 6/7![American Airlines logo]()
$324
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/37:59 pm
ROA
- MSY
1 stop4h 30m
Delta
Mon 7/67:17 pm
MSY
- ROA
1 stop4h 15m
Delta
Deal found 6/7![Delta logo]()
$332
This Delta deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/23:28 pm
ROA
- MSY
1 stop6h 04m
Delta
Mon 7/67:17 pm
MSY
- ROA
1 stop4h 15m
Delta
Deal found 6/6![Delta logo]()
$334
Best flights from Roanoke to LouisianaDiscover carefully curated flight deals from Roanoke to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 11, 2026.
Discover carefully curated flight deals from Roanoke to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 11, 2026.
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/97:50 pm
ROA
- MSY
1 stop4h 30m
Delta
Sat 9/129:57 am
MSY
- ROA
1 stop3h 44m
Delta
Deal found 6/10![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/48:10 am
ROA
- MSY
2 stops9h 57m
American Airlines
Fri 7/106:10 am
MSY
- ROA
1 stop7h 14m
American Airlines
Deal found 6/10![American Airlines logo]()
$314
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/223:00 pm
ROA
- MSY
1 stop6h 34m
United Airlines
Wed 8/265:05 am
MSY
- ROA
2 stops8h 13m
United Airlines
Deal found 6/9![United Airlines logo]()
$320
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/107:57 pm
ROA
- MSY
1 stop4h 46m
Delta
Tue 7/147:28 am
MSY
- ROA
1 stop6h 19m
Delta
Deal found 6/9![Delta logo]()
$317
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/37:59 pm
ROA
- MSY
1 stop4h 30m
Delta
Mon 7/67:17 pm
MSY
- ROA
1 stop4h 15m
Delta
Deal found 6/7![Delta logo]()
$332
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1410:26 am
ROA
- MSY
2 stops12h 31m
United Airlines
Mon 8/248:00 am
MSY
- ROA
1 stop5h 18m
United Airlines
Deal found 6/7![United Airlines logo]()
$404
This Delta deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/23:28 pm
ROA
- MSY
1 stop6h 04m
Delta
Mon 7/67:17 pm
MSY
- ROA
1 stop4h 15m
Delta
Deal found 6/6![Delta logo]()
$334
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/155:02 pm
ROA
- MSY
1 stop4h 43m
Delta
Sun 8/235:12 am
MSY
- ROA
1 stop4h 25m
Delta
Deal found 6/7![Delta logo]()
$381
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/155:02 pm
ROA
- MSY
1 stop4h 43m
Delta
Thu 8/205:16 pm
MSY
- ROA
1 stop6h 11m
Delta
Deal found 6/7![Delta logo]()
$381
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:00 am
ROA
- MSY
1 stop4h 54m
Delta
Wed 8/195:16 pm
MSY
- ROA
1 stop5h 34m
Delta
Deal found 6/7![Delta logo]()
$381
Last-minute flights from Roanoke to LouisianaDiscover last-minute flight deals from Roanoke to Louisiana. Data last updated June 11, 2026 and is based on user searches.
Discover last-minute flight deals from Roanoke to Louisiana. Data last updated June 11, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/23:28 pm
ROA
- MSY
1 stop6h 04m
Delta
Mon 7/67:17 pm
MSY
- ROA
1 stop4h 15m
Delta
Deal found 6/6![Delta logo]()
$334
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/37:59 pm
ROA
- MSY
1 stop4h 30m
Delta
Mon 7/67:17 pm
MSY
- ROA
1 stop4h 15m
Delta
Deal found 6/7![Delta logo]()
$332
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/48:10 am
ROA
- MSY
2 stops9h 57m
American Airlines
Fri 7/106:10 am
MSY
- ROA
1 stop7h 14m
American Airlines
Deal found 6/10![American Airlines logo]()
$314
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:00 am
ROA
- MSY
1 stop4h 29m
Delta
Tue 7/147:28 am
MSY
- ROA
1 stop6h 19m
Delta
Deal found 6/7![Delta logo]()
$315
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/77:53 pm
ROA
- MSY
1 stop5h 06m
American Airlines
Tue 7/1411:20 am
MSY
- ROA
2 stops9h 00m
American Airlines
Deal found 6/10![American Airlines logo]()
$356
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:00 am
ROA
- MSY
1 stop4h 29m
Delta
Mon 7/135:02 pm
MSY
- ROA
1 stop6h 23m
Delta
Deal found 6/8![Delta logo]()
$319
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/94:48 pm
ROA
- MSY
2 stops8h 10m
American Airlines
Mon 7/131:50 pm
MSY
- ROA
1 stop7h 28m
American Airlines
Deal found 6/7![American Airlines logo]()
$324
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/107:53 pm
ROA
- MSY
1 stop5h 06m
American Airlines
Sun 7/126:10 am
MSY
- ROA
1 stop7h 14m
American Airlines
Deal found 6/10![American Airlines logo]()
$309
One-way flights from Roanoke to LouisianaSearch for one-way flight options from Roanoke to Louisiana. Find affordable one-way fares based on user searches. Data last updated June 11, 2026.
Search for one-way flight options from Roanoke to Louisiana. Find affordable one-way fares based on user searches. Data last updated June 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/189:12 am
ROA
- MSY
1 stop10h 22m
Multiple Airlines
Deal found 6/10![Multiple Airlines logo]()
$156
Find flight deals from Roanoke to Louisiana
Keep the following information in mind while searching for Roanoke to Louisiana flight deals. Data was last updated June 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $309 (Delta) |
One-way from | $156 (Kiwi.com) |
Popular in | November |
Cheapest in | March |
Average price | $478 |
Cheapflights Fare Finder
Customize your flight search to find flights from Roanoke to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 11, 2026.
Use the filters below to find and compare flights from Roanoke to Louisiana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
RoanokeNew Orleans
ROA - MSY
ROAMSY
Roanoke
Wed 9/9
7:50 pm-11:20 pm
1 stop4h 30m
New Orleans Louis Armstrong
Sat 9/12
9:57 am-2:41 pm
1 stop3h 44m
$309
RoanokeNew Orleans
ROA - MSY
ROAMSY
Roanoke
Sat 7/4
8:10 am-5:07 pm
2 stops9h 57m
New Orleans Louis Armstrong
Fri 7/10
6:10 am-2:24 pm
1 stop7h 14m
$314
RoanokeNew Orleans
ROA - MSY
ROAMSY
Roanoke
Fri 7/10
7:57 pm-11:43 pm
1 stop4h 46m
New Orleans Louis Armstrong
Tue 7/14
7:28 am-2:47 pm
1 stop6h 19m
$317
RoanokeNew Orleans
ROA - MSY
ROAMSY
Roanoke
Sat 8/22
3:00 pm-8:34 pm
1 stop6h 34m
New Orleans Louis Armstrong
Wed 8/26
5:05 am-2:18 pm
2 stops8h 13m
$320
RoanokeNew Orleans
ROA - MSY
ROAMSY
Roanoke
Fri 7/3
7:59 pm-11:29 pm
1 stop4h 30m
New Orleans Louis Armstrong
Mon 7/6
7:17 pm-12:32 am
1 stop4h 15m
$332
RoanokeNew Orleans
ROA - MSY
ROAMSY
Roanoke
Thu 7/2
3:28 pm-8:32 pm
1 stop6h 04m
New Orleans Louis Armstrong
Mon 7/6
7:17 pm-12:32 am
1 stop4h 15m
$334
RoanokeNew Orleans
ROA - MSY
ROAMSY
Roanoke
Sat 8/15
5:02 pm-8:45 pm
1 stop4h 43m
New Orleans Louis Armstrong
Sun 8/23
5:12 am-10:37 am
1 stop4h 25m
$381
RoanokeNew Orleans
ROA - MSY
ROAMSY
Roanoke
Sat 8/15
5:02 pm-8:45 pm
1 stop4h 43m
New Orleans Louis Armstrong
Thu 8/20
5:16 pm-12:27 am
1 stop6h 11m
$381
RoanokeNew Orleans
ROA - MSY
ROAMSY
Roanoke
Fri 8/14
6:00 am-9:54 am
1 stop4h 54m
New Orleans Louis Armstrong
Wed 8/19
5:16 pm-11:50 pm
1 stop5h 34m
$381
RoanokeNew Orleans
ROA - MSY
ROAMSY
Roanoke
Fri 8/14
10:26 am-9:57 pm
2 stops12h 31m
New Orleans Louis Armstrong
Mon 8/24
8:00 am-2:18 pm
1 stop5h 18m
$404
Showing 1-10 of 11 resultsSorted by cheapest first
Best time to book a flight from Roanoke to Louisiana
Have a flexible travel schedule? Discover the best time to fly to Louisiana from Roanoke with our price prediction graph.
ROA-MSY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Roanoke to Louisiana
ROA-USLA
ROA-MSY
What is the cheapest month to book a flight from Roanoke to Louisiana?
Currently, January is the cheapest month in which you can book a flight from Roanoke to Louisiana (average of $248). Flying from Roanoke to Louisiana in May is currently the most expensive (average of $310). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Roanoke to Louisiana?
How far ahead should I book a flight from Roanoke to Louisiana?
To ensure you get the cheapest price possible for a flight from Roanoke to Louisiana, you should look to book at least 37 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing Louisiana
Get insights into the airlines that provide service to Louisiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisiana. Reviews last updated June 11, 2026.
Read reviews from past customers who have flown Delta,United Airlines, andAmerican Airlines from Roanoke to Louisiana. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Entertainment
7.8
Food
7.2
Boarding
8.1
Comfort
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.9
Entertainment
7.8
Food
7.2
Boarding
8.1
Comfort
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.9
Entertainment
7.8
Food
7.2
Boarding
8.1
Comfort
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.9
Entertainment
7.8
Food
7.2
Boarding
8.1
Comfort
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Roanoke to Louisiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Roanoke and Louisiana flights
Browse other Roanoke and Louisiana flight options. Last updated on June 11, 2026.
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Roanoke to Louisiana flights
Consider these flights traveling from Roanoke to Louisiana.
Top 3 airlines flying from Roanoke to Louisiana
Discover the top 3 airlines that operate flights from Roanoke to Louisiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$371 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$248 | Average$413 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$334 | Average$439 | FlexibilityNo cancel fee | On-time69% |