$274+ Cheap flights from Roanoke (ROA) to Louisiana
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/3. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — MSY
Aug 26 — Sep 21
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Roanoke to Louisiana with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Roanoke to Louisiana
Cheapest
Best
Last-minute
One-way
Cheapest flights from Roanoke to LouisianaExplore the most affordable flight options available from Roanoke to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 27, 2026.
Explore the most affordable flight options available from Roanoke to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 27, 2026.
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:35 pm
ROA
- MSY
1 stop7h 10m
American Airlines
Sun 8/166:11 am
MSY
- ROA
1 stop6h 49m
American Airlines
Deal found 7/22![American Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/91:57 pm
ROA
- MSY
2 stops10h 01m
American Airlines
Sat 9/126:00 am
MSY
- ROA
1 stop6h 51m
American Airlines
Deal found 7/22![American Airlines logo]()
$314
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:13 am
ROA
- MSY
1 stop4h 06m
Delta
Wed 11/410:59 am
MSY
- ROA
1 stop5h 20m
Delta
Deal found 7/22![Delta logo]()
$319
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/123:08 pm
ROA
- MSY
1 stop7h 54m
American Airlines
Sun 8/166:11 am
MSY
- ROA
1 stop6h 49m
American Airlines
Deal found 7/23![American Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:35 pm
ROA
- MSY
1 stop7h 10m
American Airlines
Mon 8/106:20 am
MSY
- ROA
1 stop6h 33m
American Airlines
Deal found 7/22![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:52 pm
ROA
- MSY
1 stop5h 54m
United Airlines
Sun 8/98:00 am
MSY
- ROA
1 stop4h 55m
United Airlines
Deal found 7/22![United Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:59 pm
ROA
- MSY
1 stop5h 36m
Delta
Mon 10/125:20 am
MSY
- ROA
1 stop4h 12m
Delta
Deal found 7/25![Delta logo]()
$364
Best flights from Roanoke to LouisianaDiscover carefully curated flight deals from Roanoke to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 27, 2026.
Discover carefully curated flight deals from Roanoke to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 27, 2026.
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:15 am
ROA
- MSY
1 stop5h 15m
United Airlines
Sun 9/610:24 am
MSY
- ROA
1 stop5h 45m
United Airlines
Deal found 7/26![United Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/511:20 am
ROA
- MSY
1 stop7h 11m
Delta
Sun 1/105:30 am
MSY
- ROA
1 stop4h 04m
Delta
Deal found 7/26![Delta logo]()
$334
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:52 pm
ROA
- MSY
1 stop5h 54m
United Airlines
Sun 8/98:00 am
MSY
- ROA
1 stop4h 55m
United Airlines
Deal found 7/22![United Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/53:00 pm
ROA
- MSY
1 stop6h 34m
United Airlines
Wed 9/910:25 am
MSY
- ROA
1 stop5h 44m
United Airlines
Deal found 7/26![United Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:30 am
ROA
- MSY
2 stops10h 38m
United Airlines
Wed 11/48:00 am
MSY
- ROA
1 stop5h 15m
United Airlines
Deal found 7/24![United Airlines logo]()
$404
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/810:30 am
ROA
- MSY
2 stops13h 16m
United Airlines
Wed 8/127:00 am
MSY
- ROA
2 stops11h 07m
United Airlines
Deal found 7/24![United Airlines logo]()
$439
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1310:26 am
ROA
- MSY
2 stops12h 31m
United Airlines
Sun 8/165:05 am
MSY
- ROA
2 stops8h 13m
United Airlines
Deal found 7/22![United Airlines logo]()
$520
Last-minute flights from Roanoke to LouisianaDiscover last-minute flight deals from Roanoke to Louisiana. Data last updated July 27, 2026 and is based on user searches.
Discover last-minute flight deals from Roanoke to Louisiana. Data last updated July 27, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:53 pm
ROA
- MSY
1 stop5h 06m
American Airlines
Sat 8/85:39 pm
MSY
- ROA
1 stop4h 10m
American Airlines
Deal found 7/22![American Airlines logo]()
$376
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/59:07 am
ROA
- MSY
2 stops9h 04m
American Airlines
Mon 8/106:20 am
MSY
- ROA
1 stop4h 41m
American Airlines
Deal found 7/23![American Airlines logo]()
$381
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:35 pm
ROA
- MSY
1 stop7h 10m
American Airlines
Mon 8/106:20 am
MSY
- ROA
1 stop6h 33m
American Airlines
Deal found 7/22![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:52 pm
ROA
- MSY
1 stop5h 54m
United Airlines
Sun 8/98:00 am
MSY
- ROA
1 stop4h 55m
United Airlines
Deal found 7/22![United Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/73:08 pm
ROA
- MSY
1 stop7h 54m
American Airlines
Tue 8/116:11 am
MSY
- ROA
1 stop7h 19m
American Airlines
Deal found 7/26![American Airlines logo]()
$379
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/75:52 pm
ROA
- MSY
1 stop5h 54m
United Airlines
Tue 8/115:05 am
MSY
- ROA
2 stops8h 13m
United Airlines
Deal found 7/26![United Airlines logo]()
$384
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/123:08 pm
ROA
- MSY
1 stop7h 54m
American Airlines
Sun 8/166:11 am
MSY
- ROA
1 stop6h 49m
American Airlines
Deal found 7/23![American Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:35 pm
ROA
- MSY
1 stop7h 10m
American Airlines
Sun 8/166:11 am
MSY
- ROA
1 stop6h 49m
American Airlines
Deal found 7/22![American Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/282:23 pm
ROA
- MSY
2 stops8h 23m
American Airlines
Sat 8/296:20 am
MSY
- ROA
1 stop4h 41m
American Airlines
Deal found 7/25![American Airlines logo]()
$324
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/283:00 pm
ROA
- MSY
2 stops8h 45m
United Airlines
Sat 8/299:53 am
MSY
- ROA
2 stops8h 14m
United Airlines
Deal found 7/25![United Airlines logo]()
$329
One-way flights from Roanoke to LouisianaSearch for one-way flight options from Roanoke to Louisiana. Find affordable one-way fares based on user searches. Data last updated July 27, 2026.
Search for one-way flight options from Roanoke to Louisiana. Find affordable one-way fares based on user searches. Data last updated July 27, 2026.
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/31:57 pm
ROA
- MSY
1 stop4h 15m
American Airlines
Deal found 7/25![American Airlines logo]()
$274
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/310:35 am
ROA
- MSY
2 stops10h 33m
United Airlines
Deal found 7/25![United Airlines logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:00 am
ROA
- MSY
3 stops35h 42m
Multiple Airlines
Deal found 7/25![Multiple Airlines logo]()
$1,193
Find flight deals from Roanoke to Louisiana
Keep the following information in mind while searching for Roanoke to Louisiana flight deals. Data was last updated July 27, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $309 (American Airlines) |
One-way from | $274 (American Airlines) |
Popular in | November |
Cheapest in | August |
Average price | $456 |
Cheapflights Fare Finder
Customize your flight search to find flights from Roanoke to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 27, 2026.
Use the filters below to find and compare flights from Roanoke to Louisiana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RoanokeNew Orleans
ROA - MSY
ROAMSY
Roanoke
Thu 9/3
6:15 am-10:30 am
1 stop5h 15m
New Orleans Louis Armstrong
Sun 9/6
10:24 am-5:09 pm
1 stop5h 45m
$319
RoanokeNew Orleans
ROA - MSY
ROAMSY
Roanoke
Tue 1/5
11:20 am-5:31 pm
1 stop7h 11m
New Orleans Louis Armstrong
Sun 1/10
5:30 am-10:34 am
1 stop4h 04m
$334
Quickest round-trip
RoanokeNew Orleans
ROA - MSY
ROAMSY
Roanoke
Thu 8/6
5:52 pm-10:46 pm
1 stop5h 54m
New Orleans Louis Armstrong
Sun 8/9
8:00 am-1:55 pm
1 stop4h 55m
$349
RoanokeNew Orleans
ROA - MSY
ROAMSY
Roanoke
Sat 9/5
3:00 pm-8:34 pm
1 stop6h 34m
New Orleans Louis Armstrong
Wed 9/9
10:25 am-5:09 pm
1 stop5h 44m
$399
RoanokeNew Orleans
ROA - MSY
ROAMSY
Roanoke
Wed 10/28
6:30 am-4:08 pm
2 stops10h 38m
New Orleans Louis Armstrong
Wed 11/4
8:00 am-2:15 pm
1 stop5h 15m
$404
RoanokeNew Orleans
ROA - MSY
ROAMSY
Roanoke
Sat 8/8
10:30 am-10:46 pm
2 stops13h 16m
New Orleans Louis Armstrong
Wed 8/12
7:00 am-7:07 pm
2 stops11h 07m
$439
RoanokeNew Orleans
ROA - MSY
ROAMSY
Roanoke
Thu 8/13
10:26 am-9:57 pm
2 stops12h 31m
New Orleans Louis Armstrong
Sun 8/16
5:05 am-2:18 pm
2 stops8h 13m
$520
Cheapest one-way
Quickest one-way
RoanokeNew Orleans
ROA - MSY
ROAMSY
Roanoke
Sat 10/3
1:57 pm-5:12 pm
1 stop4h 15m
$274
RoanokeNew Orleans
ROA - MSY
ROAMSY
Roanoke
Thu 1/7
6:00 am-9:32 am
1 stop4h 32m
$274
RoanokeNew Orleans
ROA - MSY
ROAMSY
Roanoke
Sat 10/3
10:35 am-8:08 pm
2 stops10h 33m
$279
Showing 1-10 of 11 resultsSorted by cheapest first
Best time to book a flight from Roanoke to Louisiana
Have a flexible travel schedule? Discover the best time to fly to Louisiana from Roanoke with our price prediction graph.
ROA-MSY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Roanoke to Louisiana
ROA-USLA
ROA-MSY
What is the cheapest month to book a flight from Roanoke to Louisiana?
Currently, August is the cheapest month in which you can book a flight from Roanoke to Louisiana (average of $338). Flying from Roanoke to Louisiana in November is currently the most expensive (average of $788). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Roanoke to Louisiana?
Airfare is typical for this route at the moment.
Roanoke to Louisiana flights typically cost between $308 and $726 in August.The cheapest round-trip price found within the last 5 days was $309 on American Airlines (Aug 13-Aug 16).
How far ahead should I book a flight from Roanoke to Louisiana?
To ensure you get the cheapest price possible for a flight from Roanoke to Louisiana, you should look to book at least 39 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing Louisiana
Get insights into the airlines that provide service to Louisiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisiana. Reviews last updated July 27, 2026.
Read reviews from past customers who have flown Delta,United Airlines, andAmerican Airlines from Roanoke to Louisiana. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.8
Food
7.2
Crew
8.5
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.8
Food
7.2
Crew
8.5
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.8
Food
7.2
Crew
8.5
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.8
Food
7.2
Crew
8.5
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Roanoke to Louisiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for Roanoke to Louisiana
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Louisiana by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Roanoke to Louisiana by cabin class
Find flights from Roanoke to Louisiana, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Roanoke and Louisiana flights
Browse other Roanoke and Louisiana flight options. Last updated on July 27, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Roanoke to Louisiana flights
Consider these flights traveling from Roanoke to Louisiana.
Top 3 airlines flying from Roanoke to Louisiana
Discover the top 3 airlines that operate flights from Roanoke to Louisiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$388 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$283 | Average$430 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$363 | Average$447 | FlexibilityNo cancel fee | On-time69% |