La Crosse

Cheap flights from Knoxville to La Crosse (TYS - LSE)

TYS — LSE
Jul 23 — Jul 301
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Best time to book a flight from Knoxville to La Crosse

Have a flexible travel schedule? Discover the best time to fly to La Crosse from Knoxville with our price prediction graph.
Estimated round-trip price
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Related info for your journey

Find useful and relevant information for your journey from Knoxville to La Crosse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • Can I find deals for flights from Knoxville to La Crosse that include hotel bookings?

    Yes. In addition to deals on Knoxville to La Crosse flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to La Crosse?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to La Crosse.

  • Can I find deals for business class flights from Knoxville to La Crosse?

    Yes. Cheapflights offers flight deals from Knoxville to La Crosse by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

Traveling to a place near La Crosse?

Book flights to La Crosse if you plan to visit one of these locations
Decorah

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Top airline flying from Knoxville to La Crosse

Discover the top airline that operate flights from Knoxville to La Crosse. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$400Average$445FlexibilityNo cancel feeOn-time71%

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