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Key Largo

$54+ Cheap flights from Durham, NC to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/26. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — MIA
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheapflights Tip: The best prices from Durham to Key Largo are usually found in October or January, booked 40 days in advance, depart on a Friday or Sunday and return on a Thursday

Cheap flight deals from Durham to Key Largo

Keep the following information in mind while searching for Durham to Key Largo flight deals. Data was last updated September 17, 2025.

Round-trip from

$94
(Kiwi.com)

One-way from

$54
(Cheapflightsfares)

Popular in

December

Cheapest in

October

Average price

$187
From Durham to Key Largo
Search Deals
One-way flight from Durham to Key Largo
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($13 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Durham to Key Largo

Cheapest flights from Durham to Key Largo
Explore the most affordable flight options available from Durham to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/191:51 pmRDU - MIA
Nonstop2h 12mFrontier
Thu 10/2310:42 amMIA - RDU
Nonstop2h 14mFrontier
Deal found 9/16$94
This Priceline deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/313:55 pmRDU - MIA
Nonstop2h 12mFrontier
Mon 11/312:52 pmMIA - RDU
Nonstop2h 14mFrontier
Deal found 9/15$95
This Cheapflightsfares deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/131:51 pmRDU - MIA
Nonstop2h 12mFrontier
Thu 10/1610:42 amMIA - RDU
Nonstop2h 14mFrontier
Deal found 9/16$98
This Priceline deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/191:51 pmRDU - MIA
Nonstop2h 12mMultiple Airlines
Thu 10/2310:51 amMIA - RDU
1 stop9h 34mMultiple Airlines
Deal found 9/16$100
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/142:33 pmRDU - MIA
1 stop8h 37mMultiple Airlines
Thu 10/1610:42 amMIA - RDU
Nonstop2h 14mMultiple Airlines
Deal found 9/15$101
This Priceline deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/36:42 pmRDU - MIA
1 stop5h 30mFrontier
Mon 10/64:15 pmMIA - RDU
Nonstop2h 19mFrontier
Deal found 9/15$106
This Booking.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:45 amRDU - MIA
1 stop10h 30mFrontier
Mon 10/64:15 pmMIA - RDU
Nonstop2h 19mFrontier
Deal found 9/15$107
This Cheapflightsfares deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/231:51 pmRDU - MIA
Nonstop2h 12mFrontier
Sun 10/2610:42 amMIA - RDU
Nonstop2h 14mFrontier
Deal found 9/15$108
This Frontier deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/91:51 pmRDU - MIA
Nonstop2h 12mFrontier
Thu 10/1610:42 amMIA - RDU
Nonstop2h 14mFrontier
Deal found 9/14$109
This Cheapflightsfares deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/297:25 pmRDU - MIA
Nonstop2h 13mFrontier
Sat 10/45:35 pmMIA - RDU
1 stop6h 00mFrontier
Deal found 9/15$110
This Frontier deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/37:25 pmRDU - MIA
Nonstop2h 13mFrontier
Sun 10/59:16 pmMIA - RDU
1 stop10h 33mFrontier
Deal found 9/15$111
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/197:15 pmRDU - MIA
1 stop5h 19mFrontier
Fri 10/2410:42 amMIA - RDU
Nonstop2h 14mFrontier
Deal found 9/14$112

Cheapflights Fare Finder

 
Customize your flight search to find flights from Durham to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Durham to Key Largo that are best for you.

Fly from

Durham

Fly to

Key Largo

Route

Depart

Return

Price

RaleighMiami

RDU - MIA

RDUMIA

Raleigh-Durham

Wed 10/15

6:20 am-10:55 am

1 stop4h 35m

Miami

Fri 10/17

7:05 pm-11:50 pm

1 stop4h 45m

$151

RaleighMiami

RDU - MIA

RDUMIA

Raleigh-Durham

Tue 10/14

12:20 pm-9:55 pm

2 stops9h 35m

Miami

Thu 10/16

7:05 am-10:40 am

1 stop3h 35m

$156

RaleighMiami

RDU - MIA

RDUMIA

Raleigh-Durham

Wed 10/15

6:10 am-3:55 pm

2 stops9h 45m

Miami

Wed 10/22

6:55 am-10:30 am

1 stop3h 35m

$156

RaleighMiami

RDU - MIA

RDUMIA

Raleigh-Durham

Sat 11/15

3:30 pm-9:40 pm

2 stops6h 10m

Miami

Wed 11/19

1:30 pm-5:55 pm

1 stop4h 25m

$156

RaleighMiami

RDU - MIA

RDUMIA

Raleigh-Durham

Tue 12/9

6:10 am-4:10 pm

2 stops10h 00m

Miami

Tue 12/16

5:10 pm-10:15 pm

1 stop5h 05m

$156

RaleighMiami

RDU - MIA

RDUMIA

Raleigh-Durham

Sat 10/25

1:45 pm-9:50 pm

2 stops8h 05m

Miami

Sat 11/1

5:45 am-1:15 pm

1 stop7h 30m

$156

RaleighMiami

RDU - MIA

RDUMIA

Raleigh-Durham

Sat 10/4

8:20 am-10:31 am

Nonstop2h 11m

Miami

Tue 10/7

6:13 pm-8:25 pm

Nonstop2h 12m

$157

RaleighMiami

RDU - MIA

RDUMIA

Raleigh-Durham

Fri 10/31

8:10 am-10:20 am

Nonstop2h 10m

Miami

Thu 11/6

6:13 pm-8:25 pm

Nonstop2h 12m

$157

RaleighMiami

RDU - MIA

RDUMIA

Raleigh-Durham

Thu 10/2

8:20 am-10:31 am

Nonstop2h 11m

Miami

Thu 10/9

6:13 pm-8:25 pm

Nonstop2h 12m

$157

RaleighMiami

RDU - MIA

RDUMIA

Raleigh-Durham

Mon 10/27

3:50 pm-10:05 pm

2 stops6h 15m

Miami

Thu 10/30

5:15 pm-11:50 pm

2 stops6h 35m

$161

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/17

Showing 1-10 of 20 results
1
2

Best time to book a flight from Durham to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to Key Largo

How far ahead should I book a flight from Durham to Key Largo?

Use this chart to determine the optimal time to book a round-trip flight from Durham to Key Largo. Price data was last updated on September 12, 2025.

The best time to book flights from Durham to Key Largo is 40 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Durham to Key Largo?

Currently, September is the cheapest month in which you can book a flight from Durham to Key Largo (average of $232). Flying from Durham to Key Largo in March is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to KE9?

Find hourly flight availability from Durham to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

When flying from Durham to Key Largo, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What is the cheapest day to fly from Durham to Key Largo?

Use this chart to determine the cheapest time to fly round-trip from Durham to Key Largo. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Durham to Key Largo flight should consider departing on Wednesday at noon when fares are most often at their lowest. Tuesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Durham to Key Largo

Explore weekly flight availability from Durham to Key Largo. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 17, 2025.

The most flights from DU8 to KE9 are scheduled on a Monday (19 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (13 on average).

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated September 17, 2025.
Peruse reviews from past customers who have flown with Delta, American Airlines, and JetBlue from Durham to Key Largo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Brian,Sep 2023

GSO - LGA

Entire process from checking bags to flight to landing to luggage retrieval was very smooth.
Delta
8.0
Very good
7,961 reviews
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Brian,Sep 2023

GSO - LGA

Entire process from checking bags to flight to landing to luggage retrieval was very smooth.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Brian,Sep 2023

GSO - LGA

Entire process from checking bags to flight to landing to luggage retrieval was very smooth.
JetBlue
7.2
Good
2,914 reviews
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Brian,Sep 2023

GSO - LGA

Entire process from checking bags to flight to landing to luggage retrieval was very smooth.
Spirit Airlines
6.3
Okay
8,023 reviews
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Brian,Sep 2023

GSO - LGA

Entire process from checking bags to flight to landing to luggage retrieval was very smooth.
Frontier
5.8
Fair
3,173 reviews
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Brian,Sep 2023

GSO - LGA

Entire process from checking bags to flight to landing to luggage retrieval was very smooth.

Related info for your journey

Find useful and relevant information for your journey from Durham to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Durham to Key Largo flight route?

    Within the past month, 98 users have taken a look at flights from Durham to Key Largo.

  • How long is the flight from Durham to Key Largo?

    A quick flight from Durham to Key Largo can take about 4h 35m. Southwest provides one of the quickest options available for as low as $151. Airlines will cover a distance of 702 mi.

  • What are the most reliable airlines from Durham to Key Largo?

    No one likes to see their flight delayed. When booking a flight from Durham to Key Largo consider choosing EL AL (100%), Envoy Air (85%) or Iberia (81%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Durham to Key Largo?

    The cheapest flight price from Durham to Key Largo is $44. On average you can expect to pay $476. The most popular route, (Raleigh-Durham - Miami), can usually be booked for $101.

  • Can I find deals for flights from Durham to Key Largo that include hotel bookings?

    Yes. In addition to deals on Durham to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Key Largo.

  • Can I find deals for business class flights from Durham to Key Largo?

    Yes. Cheapflights offers flight deals from Durham to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to Key Largo?

    Currently, September is the cheapest month in which you can book a flight from Durham to Key Largo (average of $232). Flying from Durham to Key Largo in March is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 9 airlines flying from Durham to Key Largo

Discover the top 9 airlines that operate flights from Durham to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$37Average$126FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$40Average$133FlexibilityNo cancel feeOn-time65%
JetBlueCheapest$53Average$171FlexibilityNo cancel feeOn-time62%
DeltaCheapest$69Average$300FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$123Average$419FlexibilityNo cancel feeOn-time69%
Alaska AirlinesCheapest$126Average$186FlexibilityNo cancel feeOn-time75%
American AirlinesCheapest$137Average$361FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$150Average$350FlexibilityNo cancel feeOn-time63%
Breeze AirwaysCheapest$159Average$258FlexibilityNo cancel feeOn-timeN/A

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