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$542+ Cheap flights from Panama City, FL (ECP) to Italy

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/27. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — NAP
Nov 13 — Nov 201
Thu 11/13
Thu 11/20
1 adult, Economy
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Cheap flight deals from Panama City to Italy

Keep the following information in mind while searching for Panama City to Italy flight deals. Data was last updated October 14, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$542
(United Airlines)

Popular in

May

Cheapest in

January

Average price

$871
Provider with most accurate pricing for Panama City NW Florida Beaches-Rome (ROM) flight deals.
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Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-Rome (ROM) flights.
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From Panama City NW Florida Beaches to Italy
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Highest demand for flights based on searches. 28% potential increase in price ($435 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($79 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Panama City to Italy

Cheapest flights from Panama City to Italy
Explore the most affordable flight options available from Panama City to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 14, 2025.

This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/276:30 amECP - VCE
2 stops19h 25mUnited Airlines
Thu 12/46:55 amVCE - ECP
2 stops21h 54mUnited Airlines
Deal found 10/13$542
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/276:30 amECP - VCE
2 stops19h 25mMultiple Airlines
Thu 12/48:00 amVCE - ECP
3 stops20h 49mMultiple Airlines
Deal found 10/13$548
This KLM deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/281:32 pmECP - FCO
1 stop11h 23mKLM
Fri 12/510:05 amFCO - ECP
1 stop14h 54mKLM
Deal found 10/13$555
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/286:30 amECP - FCO
2 stops18h 15mUnited Airlines
Fri 12/57:05 amFCO - ECP
2 stops40h 06mUnited Airlines
Deal found 10/13$561
This KLM deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/281:25 pmECP - FCO
1 stop14h 05mKLM
Wed 11/512:40 pmFCO - ECP
1 stop17h 30mKLM
Deal found 10/13$656
This Delta deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/285:00 pmECP - FCO
2 stops20h 45mDelta
Wed 11/510:05 amFCO - ECP
2 stops20h 05mDelta
Deal found 10/13$669
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/236:30 amECP - FCO
2 stops21h 25mUnited Airlines
Sun 10/2611:00 amFCO - ECP
2 stops32h 57mUnited Airlines
Deal found 10/14$1,173
This KLM deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/234:25 pmECP - FCO
1 stop11h 40mKLM
Sun 10/269:05 amFCO - ECP
1 stop16h 50mKLM
Deal found 10/14$1,456

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 14, 2025.
Use the filters below to find and compare flights from Panama City to Italy that are best for you.

Fly from

Panama City

Fly to

Italy

Route

Depart

Return

Price

Panama CityVenice

ECP - VCE

ECPVCE

Panama City NW Florida Beaches

Thu 11/27

6:30 am-8:55 am

2 stops19h 25m

Venice Marco Polo

Thu 12/4

6:55 am-9:49 pm

2 stops21h 54m

$542

Panama CityVenice

ECP - VCE

ECPVCE

Panama City NW Florida Beaches

Fri 11/28

6:30 am-8:55 am

2 stops19h 25m

Venice Marco Polo

Fri 12/5

10:30 am-9:49 pm

2 stops18h 19m

$542

Panama CityVenice

ECP - VCE

ECPVCE

Panama City NW Florida Beaches

Thu 11/27

6:30 am-8:55 am

2 stops19h 25m

Venice Marco Polo

Thu 12/4

8:00 am-9:49 pm

3 stops20h 49m

$548

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Fri 11/28

1:32 pm-10:30 am

1 stop13h 58m

Rome Fiumicino

Fri 12/5

6:10 am-3:25 pm

2 stops16h 15m

$556

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Fri 11/28

6:30 am-7:45 am

2 stops18h 15m

Rome Fiumicino

Fri 12/5

7:05 am-4:11 pm

2 stops40h 06m

$561

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Tue 10/28

1:25 pm-9:30 am

1 stop14h 05m

Rome Fiumicino

Wed 11/5

12:45 pm-11:10 pm

2 stops17h 25m

$657

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Tue 10/28

5:00 pm-7:45 pm

2 stops20h 45m

Rome Fiumicino

Wed 11/5

10:05 am-11:10 pm

2 stops20h 05m

$669

Panama CityVenice

ECP - VCE

ECPVCE

Panama City NW Florida Beaches

Fri 3/27

4:55 pm-6:30 pm

2 stops19h 35m

Venice Marco Polo

Tue 3/31

6:30 am-8:06 pm

2 stops20h 36m

$753

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Sun 1/4

9:22 am-7:55 am

1 stop15h 33m

Rome Fiumicino

Sun 2/8

12:40 pm-10:42 pm

1 stop17h 02m

$770

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Sun 1/4

9:22 am-10:30 am

1 stop18h 08m

Rome Fiumicino

Sun 2/8

12:45 pm-10:42 pm

2 stops16h 57m

$771

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/14

Showing 1-10 of 17 results
1
2

Best time to book a flight from Panama City to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Italy

What is the cheapest month to book a flight from Panama City, Florida to Italy?

Currently, October is the cheapest month in which you can book a flight from Panama City, Florida to Italy (average of $516). Flying from Panama City, Florida to Italy in June is currently the most expensive (average of $1,241). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to IT?

Find hourly flight availability from Panama City to Italy. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 14, 2025.

It’s optimal to fly from Panama City, Florida to Italy in the afternoon. By choosing this option you can save up to 29% on the cost of your flight, compared to a flight at noon.

What is the cheapest day to fly from Panama City, Florida to Italy?

Use this chart to determine the cheapest time to fly round-trip from Panama City to Italy. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Panama City, Florida to Italy flight should consider departing on Tuesday afternoons when fares are most often at their lowest. Saturday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Italy

Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated October 14, 2025.
Read through reviews of airlines operating flights from Panama City to Italy, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,975 reviews

Comfort

7.9

Boarding

8.2

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
8.0
Very good
7,975 reviews
Delta
8.0
Very good
7,975 reviews

Comfort

7.9

Boarding

8.2

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
United Airlines
7.4
Good
8,976 reviews
Delta
8.0
Very good
7,975 reviews

Comfort

7.9

Boarding

8.2

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
11,042 reviews
Delta
8.0
Very good
7,975 reviews

Comfort

7.9

Boarding

8.2

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Italy?

    Panama City NW Florida Beaches (ECP), located 16.0 mi from the city center, is the airport you fly out of when you book flights from Panama City to Italy.

  • How long is the flight from Panama City, Florida to Italy?

    Departing from Panama City, Florida to Italy will take you 13h 58m. Airlines will cover a distance of 5228 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Panama City to Italy that include hotel bookings?

    Yes. In addition to deals on Panama City to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Italy.

  • Can I find deals for business class flights from Panama City to Italy?

    Yes. Cheapflights offers flight deals from Panama City to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Italy?

    Currently, October is the cheapest month in which you can book a flight from Panama City, Florida to Italy (average of $516). Flying from Panama City, Florida to Italy in June is currently the most expensive (average of $1,241). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Panama City to Italy

Discover the top airline that operate flights from Panama City to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$729Average$1,436FlexibilityNo cancel feeOn-timeN/A

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