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$695+ Cheap flights from Panama City, FL (ECP) to Italy

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — NAP
Aug 25 — Sep 11
Mon 8/25
Mon 9/1
1 adult, Economy
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Cheap flight deals from Panama City to Italy

Keep the following information in mind while searching for Panama City to Italy flight deals. Data was last updated August 20, 2025.

Round-trip from

$695
(Delta)

Popular in

May

Cheapest in

November
From Panama City NW Florida Beaches to Italy
Search Deals
Highest demand for flights based on searches. 21% potential increase in price ($290 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($78 potential savings vs. average RT price).
Search Deals

Find flight deals from Panama City to Italy

Cheapest flights from Panama City to Italy
Explore the most affordable flight options available from Panama City to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 20, 2025.

This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/105:00 pmECP - VCE
2 stops17h 25mDelta
Sun 12/216:10 amVCE - ECP
2 stops20h 48mDelta
Deal found 8/19$695
This eDestinos deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/64:25 pmECP - FCO
2 stops19h 20mScandinavian Airlines
Wed 10/227:35 pmFCO - ECP
2 stops34h 35mScandinavian Airlines
Deal found 8/18$735
This KLM deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/59:24 amECP - VCE
1 stop19h 11mKLM
Tue 9/911:15 amVCE - ECP
1 stop15h 33mKLM
Deal found 8/20$761
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/64:25 pmECP - FCO
1 stop11h 40mDelta
Wed 10/2210:10 amFCO - ECP
2 stops29h 34mDelta
Deal found 8/18$770
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/59:24 amECP - VCE
1 stop19h 11mDelta
Tue 9/91:30 pmVCE - ECP
2 stops28h 04mDelta
Deal found 8/20$775
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/22:05 pmECP - FCO
1 stop14h 00mDelta
Thu 10/99:45 amFCO - ECP
1 stop20h 25mDelta
Deal found 8/18$825
This Expedia deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/55:02 pmECP - VCE
2 stops20h 38mAir France
Tue 9/96:15 amVCE - ECP
2 stops20h 33mAir France
Deal found 8/20$840
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/121:35 pmECP - FCO
1 stop14h 30mDelta
Thu 10/236:05 amFCO - ECP
2 stops18h 07mDelta
Deal found 8/18$906
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/231:35 pmECP - FCO
1 stop14h 30mDelta
Sun 10/266:10 amFCO - ECP
2 stops17h 22mDelta
Deal found 8/18$961
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/76:30 amECP - FCO
2 stops21h 25mUnited Airlines
Sun 10/122:40 pmFCO - ECP
2 stops38h 08mUnited Airlines
Deal found 8/20$972
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/76:00 amECP - FCO
1 stop18h 35mDelta
Sun 10/126:30 amFCO - ECP
2 stops15h 50mDelta
Deal found 8/18$986
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/512:01 pmECP - VCE
2 stops14h 54mAmerican Airlines
Tue 9/96:25 amVCE - ECP
3 stops18h 11mAmerican Airlines
Deal found 8/20$4,207

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
Use the filters below to find and compare flights from Panama City to Italy that are best for you.

Fly from

Panama City

Fly to

Italy

Route

Depart

Return

Price

Panama CityVenice

ECP - VCE

ECPVCE

Panama City NW Florida Beaches

Wed 12/10

5:00 pm-5:25 pm

2 stops17h 25m

Venice Marco Polo

Sun 12/21

6:10 am-7:58 pm

2 stops20h 48m

$695

Panama CityVenice

ECP - VCE

ECPVCE

Panama City NW Florida Beaches

Wed 12/10

5:00 pm-5:25 pm

2 stops17h 25m

Venice Marco Polo

Mon 12/22

6:10 am-5:51 pm

2 stops18h 41m

$695

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Mon 10/6

4:25 pm-6:45 pm

2 stops19h 20m

Rome Fiumicino

Wed 10/22

7:35 pm-11:10 pm

2 stops34h 35m

$735

Panama CityVenice

ECP - VCE

ECPVCE

Panama City NW Florida Beaches

Fri 9/5

9:24 am-11:35 am

1 stop19h 11m

Venice Marco Polo

Tue 9/9

11:15 am-7:48 pm

1 stop15h 33m

$761

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Mon 10/6

4:25 pm-11:05 am

1 stop11h 40m

Rome Fiumicino

Wed 10/22

10:10 am-8:44 am

2 stops29h 34m

$770

Panama CityVenice

ECP - VCE

ECPVCE

Panama City NW Florida Beaches

Fri 9/5

9:24 am-11:35 am

1 stop19h 11m

Venice Marco Polo

Tue 9/9

1:30 pm-10:34 am

2 stops28h 04m

$775

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Thu 10/2

2:05 pm-11:05 am

1 stop14h 00m

Rome Fiumicino

Thu 10/9

9:45 am-11:10 pm

1 stop20h 25m

$825

Panama CityVenice

ECP - VCE

ECPVCE

Panama City NW Florida Beaches

Fri 9/5

5:02 pm-8:40 pm

2 stops20h 38m

Venice Marco Polo

Tue 9/9

6:15 am-7:48 pm

2 stops20h 33m

$840

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Sun 10/12

1:35 pm-11:05 am

1 stop14h 30m

Rome Fiumicino

Thu 10/23

6:05 am-5:12 pm

2 stops18h 07m

$906

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Thu 10/23

1:35 pm-11:05 am

1 stop14h 30m

Rome Fiumicino

Sun 10/26

6:10 am-5:32 pm

2 stops17h 22m

$961

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/19

Showing 1-10 of 14 results
1
2

Best time to book a flight from Panama City to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Italy

What is the cheapest month to book a flight from Panama City, Florida to Italy?

Currently, January is the cheapest month in which you can book a flight from Panama City, Florida to Italy (average of $703). Flying from Panama City, Florida to Italy in June is currently the most expensive (average of $1,205). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to IT?

Find hourly flight availability from Panama City to Italy. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City, Florida to Italy as you normally would.

Reviews of airlines servicing Italy

Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated August 20, 2025.
Read through reviews of airlines operating flights from Panama City to Italy, such as Delta, KLM, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,982 reviews

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
8.0
Very good
7,982 reviews
Delta
8.0
Very good
7,982 reviews

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
KLM
7.8
Good
1,388 reviews
Delta
8.0
Very good
7,982 reviews

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
United Airlines
7.4
Good
8,928 reviews
Delta
8.0
Very good
7,982 reviews

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,982 reviews

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Italy?

    Panama City NW Florida Beaches (ECP), located 16.0 mi from the city center, is the airport you fly out of when you book flights from Panama City to Italy.

  • How long is the flight from Panama City, Florida to Italy?

    Departing from Panama City, Florida to Italy will take you 17h 25m. Airlines will cover a distance of 5112 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Panama City to Italy that include hotel bookings?

    Yes. In addition to deals on Panama City to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Italy.

  • Can I find deals for business class flights from Panama City to Italy?

    Yes. Cheapflights offers flight deals from Panama City to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Italy?

    Currently, January is the cheapest month in which you can book a flight from Panama City, Florida to Italy (average of $703). Flying from Panama City, Florida to Italy in June is currently the most expensive (average of $1,205). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Panama City to Italy

Discover the top 2 airlines that operate flights from Panama City to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$724Average$1,147FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$977Average$1,153FlexibilityNo cancel feeOn-time71%

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