HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Istanbul

$542+ Cheap flights from Panama to Istanbul

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/8. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — IST
Jul 18 — Jul 251
Sat 7/18
Sat 7/25
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Panama to Istanbul with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Panama to Istanbul

Cheapest flights from Panama to Istanbul
Explore the most affordable flight options available from Panama to Istanbul. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 18, 2026.

This Air France deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/139:55 pm
PTY
-
IST
1 stop21h 35m
Multiple Airlines
Wed 9/235:20 pm
IST
-
PTY
2 stops34h 25m
Multiple Airlines
Deal found 6/13$1,140
This KLM deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/149:55 pm
PTY
-
IST
2 stops19h 25m
KLM
Wed 9/235:20 pm
IST
-
PTY
2 stops34h 25m
KLM
Deal found 6/16$1,144
This FlightHub deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/138:25 pm
PTY
-
IST
1 stop33h 30m
Air Europa
Thu 10/223:45 pm
IST
-
PTY
1 stop34h 55m
Air Europa
Deal found 6/18$1,157
This KLM deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/139:55 pm
PTY
-
IST
2 stops19h 25m
KLM
Wed 9/235:20 pm
IST
-
PTY
2 stops34h 25m
KLM
Deal found 6/13$1,159
This KLM deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:50 pm
PTY
-
IST
1 stop22h 30m
KLM
Sun 10/46:00 am
IST
-
PTY
2 stops21h 45m
KLM
Deal found 6/13$1,184
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/210:00 am
PTY
-
IST
2 stops27h 25m
United Airlines
Wed 9/95:40 am
IST
-
PTY
2 stops40h 34m
United Airlines
Deal found 6/14$1,187
This United Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/139:45 am
PTY
-
IST
2 stops19h 15m
United Airlines
Sun 9/205:50 am
IST
-
PTY
2 stops40h 24m
United Airlines
Deal found 6/17$1,188
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/29:45 am
PTY
-
IST
2 stops19h 15m
United Airlines
Fri 10/95:40 am
IST
-
PTY
2 stops21h 51m
United Airlines
Deal found 6/16$1,192
This FlightHub deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/218:25 pm
PTY
-
IST
1 stop33h 30m
Air Europa
Mon 11/24:35 pm
IST
-
PTY
1 stop35h 10m
Air Europa
Deal found 6/18$1,194
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/169:45 am
PTY
-
IST
2 stops19h 15m
United Airlines
Thu 10/221:55 pm
IST
-
PTY
2 stops37h 36m
United Airlines
Deal found 6/16$1,208
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2710:55 pm
PTY
-
IST
2 stops38h 20m
United Airlines
Wed 8/121:55 pm
IST
-
PTY
2 stops46h 09m
United Airlines
Deal found 6/16$1,212

Find flight deals from Panama to Istanbul

Keep the following information in mind while searching for Panama to Istanbul flight deals. Data was last updated June 18, 2026.

Round-trip from

$1,140
(Air France)

One-way from

$542
(Kiwi.com)

Popular in

June

Cheapest in

March

Average price

$1,407
From Panama to Istanbul
Search Deals
One-way flight from Panama to Istanbul
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($30 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Istanbul that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2026.
Use the filters below to find and compare flights from Panama to Istanbul that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Tue 11/3

8:55 am-6:10 pm

2 stops25h 15m

Istanbul

Thu 11/12

6:30 am-8:02 pm

2 stops45h 32m

$1,188

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Fri 10/2

9:45 am-1:00 pm

2 stops19h 15m

Istanbul

Fri 10/9

5:40 am-7:31 pm

2 stops21h 51m

$1,192

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Tue 10/13

9:45 am-9:15 pm

2 stops27h 30m

Istanbul

Thu 10/22

1:55 pm-7:31 pm

2 stops37h 36m

$1,212

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Tue 12/1

9:30 pm-2:55 pm

1 stop33h 25m

Istanbul

Fri 12/11

4:35 pm-7:45 pm

1 stop35h 10m

$1,232

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Tue 10/20

9:45 am-1:00 pm

2 stops19h 15m

Istanbul

Tue 11/3

6:30 am-8:02 pm

2 stops45h 32m

$1,239

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Thu 7/9

9:45 am-9:35 pm

2 stops27h 50m

Istanbul

Thu 7/16

5:40 am-4:04 am

2 stops30h 24m

$1,294

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Wed 10/21

8:10 am-9:25 pm

2 stops29h 15m

Istanbul

Mon 11/2

6:30 am-6:13 am

2 stops31h 43m

$1,353

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Tue 9/1

9:55 pm-3:30 am

1 stop21h 35m

Istanbul

Thu 9/17

4:25 am-4:50 pm

2 stops20h 25m

$1,359
Quickest round-trip

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Fri 10/2

9:55 pm-1:20 am

2 stops19h 25m

Istanbul

Fri 10/9

6:00 am-4:50 pm

1 stop18h 50m

$1,366

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Wed 10/21

6:50 pm-3:30 am

2 stops24h 40m

Istanbul

Mon 11/2

7:15 am-8:20 pm

1 stop21h 05m

$1,378

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/13

Showing 1-10 of 19 resultsSorted by cheapest first
1
2

Best time to book a flight from Panama to Istanbul

Have a flexible travel schedule? Discover the best time to fly to Istanbul from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Istanbul

What is the cheapest month to book a flight from Panama to Istanbul?

Currently, July is the cheapest month in which you can book a flight from Panama to Istanbul (average of $522). Flying from Panama to Istanbul in September is currently the most expensive (average of $992). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to IST?

Find hourly flight availability from Panama to Istanbul. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 18, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama to Istanbul as you normally would.

How often are flights from Panama to Istanbul delayed?

About 23% of weekly flights between Panama and Istanbul have experienced delays in the past year, with the average delay time being 156 minutes.

What is the most punctual flight time for Panama to Istanbul flights?

Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the evening tend to experience delays more often.

What day of the week experiences the fewest flight delays on this route?

Wednesday tends to have the lowest number of delays on this route, whereas Tuesday has historically faced a higher average of delays compared to other days of the week.

Which airline has the best punctuality record on Panama to Istanbul flights?

Over the last year, Turkish Airlines have had the lowest number of delays on this route, with just 23% of flights being delayed.

How far ahead should I book a flight from Panama to Istanbul?

The best time to book flights from Panama to Istanbul is 82 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

Reviews of airlines servicing Istanbul

Get insights into the airlines that provide service to Istanbul. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Istanbul. Reviews last updated June 18, 2026.
See what other customers who have flown with KLM,Turkish Airlines, andAir Europa from Panama to Istanbul have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.8
Good
1,530 reviews

Comfort

7.7

Overall

7.8

Crew

8.4

Entertainment

7.2

Boarding

7.8

Food

7.3

Reviews

1 / 20
6.0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
KLM
7.8
Good
1,530 reviews
KLM
7.8
Good
1,530 reviews

Comfort

7.7

Overall

7.8

Crew

8.4

Entertainment

7.2

Boarding

7.8

Food

7.3

Reviews

1 / 20
6.0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
Turkish Airlines
7.4
Good
4,408 reviews
KLM
7.8
Good
1,530 reviews

Comfort

7.7

Overall

7.8

Crew

8.4

Entertainment

7.2

Boarding

7.8

Food

7.3

Reviews

1 / 20
6.0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
Air Europa
7.0
Good
619 reviews
KLM
7.8
Good
1,530 reviews

Comfort

7.7

Overall

7.8

Crew

8.4

Entertainment

7.2

Boarding

7.8

Food

7.3

Reviews

1 / 20
6.0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful

Related info for your journey

Find useful and relevant information for your journey from Panama to Istanbul. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama to Istanbul?

    A quick flight from Panama to Istanbul can take about 25h 15m. United Airlines provides one of the quickest options available for as low as $1,188. The distance from Panama to Istanbul is about 6717 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest flights from Panama to Istanbul?

    While on average a flight from Panama to Istanbul is generally $1,797, our data shows the cheapest flight currently is $638. When looking at the most popular route, (Panama City Tocumen Intl - Istanbul), you can expect to pay $1,574 for that flight.

  • Can I find deals for flights from Panama to Istanbul that include hotel bookings?

    Yes. In addition to deals on Panama to Istanbul flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Istanbul?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Istanbul.

  • Can I find deals for business class flights from Panama to Istanbul?

    Yes. Cheapflights offers flight deals from Panama to Istanbul by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Istanbul?

    Currently, July is the cheapest month in which you can book a flight from Panama to Istanbul (average of $522). Flying from Panama to Istanbul in September is currently the most expensive (average of $992). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 3 airlines flying from Panama to Istanbul

Discover the top 3 airlines that operate flights from Panama to Istanbul. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
Air EuropaCheapest$853Average$1,048FlexibilityNo cancel feeOn-time83%
KLMCheapest$1,142Average$2,122FlexibilityNo cancel feeOn-time75%
Turkish AirlinesCheapest$1,190Average$1,376FlexibilityNo cancel feeOn-time77%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.