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$524+ Cheap flights from Panama to Istanbul

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/5. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — IST
Aug 29 — Sep 51
Sat 8/29
Sat 9/5
1 adult, Economy
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Cheap flight deals from Panama to Istanbul

Cheapest flights from Panama to Istanbul
Explore the most affordable flight options available from Panama to Istanbul. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2026.

This Air Europa deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/148:25 pm
PTY
-
IST
1 stop33h 30m
Air Europa
Fri 9/183:45 pm
IST
-
PTY
1 stop34h 55m
Air Europa
Deal found 7/26$1,058
This Gotogate deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/208:25 pm
PTY
-
IST
1 stop33h 30m
Air Europa
Sat 9/263:45 pm
IST
-
PTY
1 stop34h 55m
Air Europa
Deal found 7/27$1,077
This Gotogate deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/158:25 pm
PTY
-
IST
1 stop33h 30m
Air Europa
Fri 9/253:45 pm
IST
-
PTY
1 stop34h 55m
Air Europa
Deal found 7/29$1,079
This Air Europa deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/188:25 pm
PTY
-
IST
1 stop33h 30m
Air Europa
Sat 9/263:45 pm
IST
-
PTY
1 stop34h 55m
Air Europa
Deal found 7/29$1,081
This Air Europa deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/108:25 pm
PTY
-
IST
1 stop33h 30m
Air Europa
Sat 10/243:45 pm
IST
-
PTY
1 stop36h 00m
Air Europa
Deal found 7/25$1,094
This Air Europa deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/198:25 pm
PTY
-
IST
1 stop33h 30m
Air Europa
Wed 9/233:45 pm
IST
-
PTY
1 stop34h 55m
Air Europa
Deal found 7/28$1,111
This Expedia deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/138:25 pm
PTY
-
IST
1 stop33h 30m
Air Europa
Fri 10/233:45 pm
IST
-
PTY
1 stop34h 55m
Air Europa
Deal found 7/28$1,115
This Air Europa deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/218:25 pm
PTY
-
IST
1 stop33h 30m
Air Europa
Wed 10/284:35 pm
IST
-
PTY
1 stop35h 10m
Air Europa
Deal found 7/25$1,130
This Justfly.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/108:25 pm
PTY
-
IST
1 stop33h 30m
Multiple Airlines
Sat 10/243:45 pm
IST
-
PTY
1 stop36h 00m
Multiple Airlines
Deal found 7/29$1,149
This Air Europa deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:25 pm
PTY
-
IST
1 stop33h 30m
Air Europa
Thu 10/223:45 pm
IST
-
PTY
1 stop34h 55m
Air Europa
Deal found 7/29$1,155

Find flight deals from Panama to Istanbul

Keep the following information in mind while searching for Panama to Istanbul flight deals. Data was last updated July 30, 2026.

Round-trip from

$1,058
(Air Europa)

One-way from

$524
(Kiwi.com)

Popular in

December

Cheapest in

March

Average price

$1,324
From Panama to Istanbul
Search Deals
One-way flight from Panama to Istanbul
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($27 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Istanbul that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2026.
Use the filters below to find and compare flights from Panama to Istanbul that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Mon 9/14

8:25 pm-1:55 pm

1 stop33h 30m

Istanbul

Fri 9/18

3:45 pm-6:40 pm

1 stop34h 55m

$1,058

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Mon 10/26

12:33 pm-12:20 pm

2 stops39h 47m

Istanbul

Tue 11/10

8:10 pm-12:40 am

2 stops36h 30m

$1,186

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Fri 1/15

8:55 am-10:45 pm

2 stops29h 50m

Istanbul

Sat 1/23

6:30 am-2:45 pm

2 stops40h 15m

$1,187

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Tue 9/15

3:30 pm-4:55 pm

2 stops41h 25m

Istanbul

Fri 9/25

5:40 am-2:14 pm

2 stops40h 34m

$1,191
Quickest round-trip

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Wed 10/21

10:20 pm-7:05 pm

Nonstop12h 45m

Istanbul

Mon 11/2

1:50 pm-8:05 pm

Nonstop14h 15m

$1,199

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Wed 10/21

10:20 pm-7:05 pm

Nonstop12h 45m

Istanbul

Wed 10/28

1:50 pm-8:05 pm

Nonstop14h 15m

$1,199

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Thu 9/3

10:55 pm-9:25 pm

2 stops38h 30m

Istanbul

Mon 9/14

1:55 pm-7:31 pm

2 stops61h 36m

$1,211

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Wed 10/21

8:25 pm-1:55 pm

1 stop33h 30m

Istanbul

Mon 11/2

4:35 pm-7:45 pm

1 stop35h 10m

$1,238

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Mon 10/26

12:33 pm-12:20 pm

2 stops39h 47m

Istanbul

Fri 11/13

1:50 pm-8:15 pm

2 stops38h 25m

$1,267
Cheapest one-way

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Wed 11/11

9:31 pm-10:50 am

3 stops53h 19m

$613

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/25

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

Best time to book a flight from Panama to Istanbul

Have a flexible travel schedule? Discover the best time to fly to Istanbul from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Istanbul

What is the cheapest month to book a flight from Panama to Istanbul?

Currently, March is the cheapest month in which you can book a flight from Panama to Istanbul (average of $1,191). Flying from Panama to Istanbul in December is currently the most expensive (average of $1,407). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to IST?

Find hourly flight availability from Panama to Istanbul. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 30, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama to Istanbul as you normally would.

How often are flights from Panama to Istanbul delayed?

About 23% of weekly flights between Panama and Istanbul have experienced delays in the past year, with the average delay time being 160 minutes.

What is the most punctual flight time for Panama to Istanbul flights?

Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the evening tend to experience delays more often.

What day of the week experiences the fewest flight delays on this route?

Wednesday tends to have the lowest number of delays on this route, whereas Tuesday has historically faced a higher average of delays compared to other days of the week.

Which airline has the best punctuality record on Panama to Istanbul flights?

Over the last year, Turkish Airlines have had the lowest number of delays on this route, with just 23% of flights being delayed.

How far ahead should I book a flight from Panama to Istanbul?

The best time to book flights from Panama to Istanbul is 83 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

Reviews of airlines servicing Istanbul

Get insights into the airlines that provide service to Istanbul. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Istanbul. Reviews last updated July 30, 2026.
See what other customers who have flown with Turkish Airlines and Air Europa from Panama to Istanbul have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Turkish Airlines
7.4
Good
4,457 reviews

Food

7.5

Boarding

7.3

Comfort

7.3

Crew

7.8

Overall

7.4

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Anonymous,Jun 2026

KRK - IST

Of course, when one books a trip in "sardine class," one realizes that comfort is an expensive option. That having been said, the seats were in the seat no comfortable. However, this was more than compensated by the excellent (for coach) food service and the helpfulness of the crew. I also loved that Turkish Airlines does not nickle-and-dime you on luggage. Yes, I would go with them again.
Turkish Airlines
7.4
Good
4,457 reviews
Turkish Airlines
7.4
Good
4,457 reviews

Food

7.5

Boarding

7.3

Comfort

7.3

Crew

7.8

Overall

7.4

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Anonymous,Jun 2026

KRK - IST

Of course, when one books a trip in "sardine class," one realizes that comfort is an expensive option. That having been said, the seats were in the seat no comfortable. However, this was more than compensated by the excellent (for coach) food service and the helpfulness of the crew. I also loved that Turkish Airlines does not nickle-and-dime you on luggage. Yes, I would go with them again.
Air Europa
7.0
Good
629 reviews
Turkish Airlines
7.4
Good
4,457 reviews

Food

7.5

Boarding

7.3

Comfort

7.3

Crew

7.8

Overall

7.4

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Anonymous,Jun 2026

KRK - IST

Of course, when one books a trip in "sardine class," one realizes that comfort is an expensive option. That having been said, the seats were in the seat no comfortable. However, this was more than compensated by the excellent (for coach) food service and the helpfulness of the crew. I also loved that Turkish Airlines does not nickle-and-dime you on luggage. Yes, I would go with them again.

Related info for your journey

Find useful and relevant information for your journey from Panama to Istanbul. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama to Istanbul?

    A quick flight from Panama to Istanbul can take about 33h 30m. Air Europa provides one of the quickest options available for as low as $1,058. The distance from Panama to Istanbul is about 6717 mi.

  • What are the cheapest flights from Panama to Istanbul?

    While on average a flight from Panama to Istanbul is generally $1,254, our data shows the cheapest flight currently is $657. When looking at the most popular route, (Panama City Tocumen Intl - Istanbul), you can expect to pay $1,199 for that flight.

  • Can I find deals for flights from Panama to Istanbul that include hotel bookings?

    Yes. In addition to deals on Panama to Istanbul flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Istanbul?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Istanbul.

  • Can I find deals for business class flights from Panama to Istanbul?

    Yes. Cheapflights offers flight deals from Panama to Istanbul by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Istanbul?

    Currently, March is the cheapest month in which you can book a flight from Panama to Istanbul (average of $1,191). Flying from Panama to Istanbul in December is currently the most expensive (average of $1,407). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Panama to Istanbul

Discover the top 2 airlines that operate flights from Panama to Istanbul. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2026.
AirlineCheapestAverageFlexibilityOn-time
Air EuropaCheapest$853Average$1,062FlexibilityNo cancel feeOn-time83%
Turkish AirlinesCheapest$1,202Average$1,375FlexibilityNo cancel feeOn-time77%

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