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$160+ Cheap flights from Jose Maria Cordova Intl (MDE) to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/14. Fares are subject to change and may not be available on all flights or dates of travel.
MDE — GYE
Aug 4 — Aug 111
Mon 8/4
Mon 8/11
1 adult, Economy
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Cheapflights Tip: The best prices from Medellín Jose Maria Cordova Intl to Guayaquil Jose Joaquin de Olmedo are usually found in January or September, booked 45 days in advance, depart on a Saturday or Thursday and return on a Friday

Cheap flight deals from Jose Maria Cordova Intl to Guayaquil

Discover tips and strategies to find the most affordable flight options for your journey from Jose Maria Cordova Intl (MDE) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 30, 2025.

Round-trip from

$278
(Copa Airlines)

One-way from

$160
(Copa Airlines)

Popular in

December

Cheapest in

January

Average price

$262
From Medellín Jose Maria Cordova Intl to Guayaquil Jose Joaquin de Olmedo
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One-way flight from Medellín Jose Maria Cordova Intl to Guayaquil Jose Joaquin de Olmedo
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Highest demand for flights based on searches. 1% potential increase in price ($3 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($3 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Jose Maria Cordova Intl to Guayaquil

Cheapest flights from Jose Maria Cordova Intl to Guayaquil
Explore the most affordable flight options available from Jose Maria Cordova Intl to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.

This Copa Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/36:37 amMDE - GYE
1 stop13h 57mCopa Airlines
Mon 9/86:32 pmGYE - MDE
1 stop14h 38mCopa Airlines
Deal found 7/29$278
This Avianca deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/186:57 pmMDE - GYE
1 stop4h 23mAvianca
Thu 9/118:50 amGYE - MDE
1 stop4h 13mAvianca
Deal found 7/30$307
This Mytrip deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/411:53 pmMDE - GYE
2 stops17h 23mMultiple Airlines
Sun 8/1711:05 amGYE - MDE
1 stop4h 43mMultiple Airlines
Deal found 7/30$362
This Booking.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/411:53 pmMDE - GYE
2 stops17h 23mLATAM Airlines
Sun 8/174:10 pmGYE - MDE
2 stops15h 30mLATAM Airlines
Deal found 7/30$407
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1512:15 amMDE - GYE
2 stops37h 31mUnited Airlines
Sun 8/242:47 pmGYE - MDE
2 stops54h 23mUnited Airlines
Deal found 7/29$2,092

Cheapflights Fare Finder

 
Customize your flight search to find flights from Jose Maria Cordova Intl to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
Use the filters below to find and compare flights from Medellín Jose Maria Cordova Intl Airport to Guayaquil that are best for you.

Fly from

Jose Maria Cordova Intl

Fly to

Guayaquil

Route

Depart

Return

Price

MedellínGuayaquil

MDE - GYE

MDEGYE

Medellín Jose Maria Cordova Intl

Wed 9/3

6:37 am-8:34 pm

1 stop13h 57m

Guayaquil Jose Joaquin de Olmedo

Mon 9/8

6:32 pm-9:10 am

1 stop14h 38m

$278

MedellínGuayaquil

MDE - GYE

MDEGYE

Medellín Jose Maria Cordova Intl

Mon 8/18

6:57 pm-11:20 pm

1 stop4h 23m

Guayaquil Jose Joaquin de Olmedo

Thu 9/11

8:50 am-1:03 pm

1 stop4h 13m

$307

MedellínGuayaquil

MDE - GYE

MDEGYE

Medellín Jose Maria Cordova Intl

Mon 8/18

7:31 am-8:18 pm

2 stops12h 47m

Guayaquil Jose Joaquin de Olmedo

Thu 9/11

4:43 pm-6:33 am

2 stops13h 50m

$416

MedellínGuayaquil

MDE - GYE

MDEGYE

Medellín Jose Maria Cordova Intl

Mon 8/18

4:23 am-8:35 am

1 stop4h 12m

Guayaquil Jose Joaquin de Olmedo

Thu 9/11

4:43 pm-6:33 am

2 stops13h 50m

$512

MedellínGuayaquil

MDE - GYE

MDEGYE

Medellín Jose Maria Cordova Intl

Fri 8/15

12:15 am-1:46 pm

2 stops37h 31m

Guayaquil Jose Joaquin de Olmedo

Sun 8/24

2:47 pm-9:10 pm

2 stops54h 23m

$2,092

MedellínGuayaquil

MDE - GYE

MDEGYE

Medellín Jose Maria Cordova Intl

Fri 11/14

12:42 pm-11:55 pm

1 stop11h 13m

$160

MedellínGuayaquil

MDE - GYE

MDEGYE

Medellín Jose Maria Cordova Intl

Mon 8/4

5:30 pm-11:20 pm

1 stop5h 50m

$181

MedellínGuayaquil

MDE - GYE

MDEGYE

Medellín Jose Maria Cordova Intl

Mon 8/4

11:53 pm-7:31 pm

2 stops19h 38m

$206

MedellínGuayaquil

MDE - GYE

MDEGYE

Medellín Jose Maria Cordova Intl

Mon 8/4

2:00 pm-5:16 pm

3 stops27h 16m

$281

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Best time to book a flight from Jose Maria Cordova Intl to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Jose Maria Cordova Intl with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medellín Jose Maria Cordova Intl Airport to Guayaquil

How far ahead should I book a flight from Medellín Jose Maria Cordova Intl Airport to Guayaquil?

Use this chart to determine the optimal time to book a round-trip flight from Jose Maria Cordova Intl to Guayaquil. Price data was last updated on July 25, 2025.

Booking 45 days in advance of your planned departure date is, on average, the best time to get cheap flights from Medellín Jose Maria Cordova Intl Airport to Guayaquil. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Medellín Jose Maria Cordova Intl Airport to Guayaquil?

Currently, April is the cheapest month in which you can book a flight from Medellín Jose Maria Cordova Intl Airport to Guayaquil (average of $440). Flying from Medellín Jose Maria Cordova Intl Airport to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDE to GYE?

Find hourly flight availability from Jose Maria Cordova Intl to Guayaquil. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 30, 2025.

It’s typically best to fly out from Medellín Jose Maria Cordova Intl Airport to Guayaquil in the afternoon. Doing so could potentially save you 59% on the flight price compared to flying at noon, which is usually more expensive.

Reviews of airlines servicing Guayaquil

Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated July 30, 2025.
Read reviews from past customers who have flown LATAM Airlines, Copa Airlines, and United Airlines from Medellín Jose Maria Cordova Intl Airport to Guayaquil. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,822 reviews

Food

6.7

Comfort

7.4

Entertainment

7.0

Boarding

7.6

Crew

8.1

Overall

7.5

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing
LATAM Airlines
7.5
Good
1,822 reviews
LATAM Airlines
7.5
Good
1,822 reviews

Food

6.7

Comfort

7.4

Entertainment

7.0

Boarding

7.6

Crew

8.1

Overall

7.5

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing
Copa Airlines
7.5
Good
1,493 reviews
LATAM Airlines
7.5
Good
1,822 reviews

Food

6.7

Comfort

7.4

Entertainment

7.0

Boarding

7.6

Crew

8.1

Overall

7.5

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing
United Airlines
7.4
Good
8,896 reviews
LATAM Airlines
7.5
Good
1,822 reviews

Food

6.7

Comfort

7.4

Entertainment

7.0

Boarding

7.6

Crew

8.1

Overall

7.5

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing
Avianca
6.7
Okay
2,387 reviews
LATAM Airlines
7.5
Good
1,822 reviews

Food

6.7

Comfort

7.4

Entertainment

7.0

Boarding

7.6

Crew

8.1

Overall

7.5

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing

Related info for your journey

Find useful and relevant information for your journey from Jose Maria Cordova Intl to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Guayaquil from Medellín Jose Maria Cordova Intl?

    Most people fly into Guayaquil Jose Joaquin de Olmedo (GYE) if they book a flight to Guayaquil from Medellín Jose Maria Cordova Intl. On average, Jose Joaquin de Olmedo has 0 inbound flights from Medellín Jose Maria Cordova Intl per day from 1 airline. Guayaquil Jose Joaquin de Olmedo is conveniently located just 2.5 mi from Guayaquil’s city center.

  • What are the cheapest airlines flying from Medellín Jose Maria Cordova Intl Airport to Guayaquil round-trip?

    Currently priced at $278, Copa Airlines will fly you from Medellín Jose Maria Cordova Intl Airport to Guayaquil and back. In addition to Copa Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Avianca and LATAM Airlines - these airlines can fly you to your destination from $307 and $416, respectively.

  • What are the cheapest airlines to fly from Medellín Jose Maria Cordova Intl Airport to Guayaquil one-way?

    $160 is the cheapest one-way deal found within the past few days, from Copa Airlines. You may also be able to find cheap deals on Avianca and LATAM Airlines, with prices starting from $181 and $206, respectively.

  • Can I find deals for flights from Jose Maria Cordova Intl to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Jose Maria Cordova Intl to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Jose Maria Cordova Intl to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jose Maria Cordova Intl to Guayaquil.

  • Can I find deals for business class flights from Jose Maria Cordova Intl to Guayaquil?

    Yes. Cheapflights offers flight deals from Jose Maria Cordova Intl to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medellín Jose Maria Cordova Intl Airport to Guayaquil?

    Currently, April is the cheapest month in which you can book a flight from Medellín Jose Maria Cordova Intl Airport to Guayaquil (average of $440). Flying from Medellín Jose Maria Cordova Intl Airport to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Jose Maria Cordova Intl to Guayaquil

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Top airline flying from Jose Maria Cordova Intl to Guayaquil

Discover the top airline that operate flights from Jose Maria Cordova Intl to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$241Average$269FlexibilityNo cancel feeOn-time71%

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