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Guayaquil

$185+ Cheap flights from Jose Maria Cordova Intl (MDE) to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/22. Fares are subject to change and may not be available on all flights or dates of travel.
MDE — GYE
feb. 28 — mar. 71
sáb. 2/28
sáb. 3/7
1 adult, Economy
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Cheapflights Tip: The best prices from Medellín Jose Maria Cordova Intl to Guayaquil Jose Joaquin de Olmedo are usually found in June or May, booked 37 days in advance, depart on a Monday or Tuesday and return on a Tuesday

Cheap flight deals from Jose Maria Cordova Intl to Guayaquil

Cheapest flights from Jose Maria Cordova Intl to Guayaquil
Explore the most affordable flight options available from Jose Maria Cordova Intl to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 29, 2026.

This Avianca deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 2/65:00 am
MDE
-
GYE
2 stops6h 25m
Avianca
sáb. 2/79:05 am
GYE
-
MDE
1 stop3h 50m
Avianca
Deal found 1/27$298
This Copa Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/15:00 am
MDE
-
GYE
1 stop8h 33m
Copa Airlines
sáb. 5/98:28 am
GYE
-
MDE
1 stop5h 47m
Copa Airlines
Deal found 1/27$304
This Priceline deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 2/46:25 pm
MDE
-
GYE
Nonstop2h 00m
Avianca
vie. 2/64:40 am
GYE
-
MDE
1 stop4h 25m
Avianca
Deal found 1/28$308
This FlightHub deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/164:10 pm
MDE
-
GYE
Nonstop2h 00m
Avianca
mié. 3/183:35 pm
GYE
-
MDE
1 stop4h 40m
Avianca
Deal found 1/26$321
This Copa Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 3/1810:46 am
MDE
-
GYE
1 stop10h 00m
Copa Airlines
sáb. 6/66:27 pm
GYE
-
MDE
1 stop13h 48m
Copa Airlines
Deal found 1/28$322
This Copa Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/165:00 am
MDE
-
GYE
1 stop8h 33m
Copa Airlines
lun. 10/198:24 am
GYE
-
MDE
1 stop6h 21m
Copa Airlines
Deal found 1/27$325
This FlightHub deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 1/309:50 am
MDE
-
GYE
1 stop4h 35m
Avianca
lun. 2/21:25 pm
GYE
-
MDE
Nonstop1h 45m
Avianca
Deal found 1/27$332
This Copa Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 3/1810:46 am
MDE
-
GYE
1 stop12h 55m
Copa Airlines
lun. 6/158:27 am
GYE
-
MDE
1 stop6h 18m
Copa Airlines
Deal found 1/27$333
This Avianca deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 2/85:00 am
MDE
-
GYE
2 stops7h 30m
Avianca
mar. 2/109:05 am
GYE
-
MDE
1 stop4h 15m
Avianca
Deal found 1/27$334

Find flight deals from Jose Maria Cordova Intl to Guayaquil

Discover tips and strategies to find the most affordable flight options for your journey from Jose Maria Cordova Intl (MDE) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated enero 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$304
(Copa Airlines)

One-way from

$185
(FlightHub)

Popular in

December

Cheapest in

June

Average price

$319
Provider with most accurate pricing for Medellín Jose Maria Cordova Intl-Guayaquil Jose Joaquin de Olmedo flight deals.
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Provider most trusted by Cheapflights users for Medellín Jose Maria Cordova Intl-Guayaquil Jose Joaquin de Olmedo flights.
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From Medellín Jose Maria Cordova Intl to Guayaquil Jose Joaquin de Olmedo
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One-way flight from Medellín Jose Maria Cordova Intl to Guayaquil Jose Joaquin de Olmedo
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($30 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Jose Maria Cordova Intl to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 29, 2026.
Use the filters below to find and compare flights from Medellín Jose Maria Cordova Intl Airport to Guayaquil that are best for you.

Fly from

Jose Maria Cordova Intl

Fly to

Guayaquil

Route

Depart

Return

Price

MedellínGuayaquil

MDE - GYE

MDEGYE

Medellín Jose Maria Cordova Intl

vie. 5/1

5:00 am-1:33 pm

1 stop8h 33m

Guayaquil Jose Joaquin de Olmedo

sáb. 5/9

8:28 am-2:15 pm

1 stop5h 47m

$304

MedellínGuayaquil

MDE - GYE

MDEGYE

Medellín Jose Maria Cordova Intl

lun. 3/16

4:10 pm-6:10 pm

Nonstop2h 00m

Guayaquil Jose Joaquin de Olmedo

mié. 3/18

3:35 pm-8:15 pm

1 stop4h 40m

$321

MedellínGuayaquil

MDE - GYE

MDEGYE

Medellín Jose Maria Cordova Intl

jue. 4/2

4:30 pm-12:02 am

1 stop7h 32m

Guayaquil Jose Joaquin de Olmedo

mar. 4/7

6:00 am-2:15 pm

1 stop8h 15m

$322

MedellínGuayaquil

MDE - GYE

MDEGYE

Medellín Jose Maria Cordova Intl

mié. 3/18

3:15 pm-11:55 pm

1 stop8h 40m

Guayaquil Jose Joaquin de Olmedo

sáb. 6/6

6:27 pm-8:15 am

1 stop13h 48m

$322

MedellínGuayaquil

MDE - GYE

MDEGYE

Medellín Jose Maria Cordova Intl

jue. 2/19

5:00 am-5:35 pm

1 stop12h 35m

Guayaquil Jose Joaquin de Olmedo

lun. 2/23

6:33 pm-8:18 am

1 stop13h 45m

$322

MedellínGuayaquil

MDE - GYE

MDEGYE

Medellín Jose Maria Cordova Intl

jue. 3/5

8:37 am-1:34 pm

1 stop4h 57m

Guayaquil Jose Joaquin de Olmedo

mié. 6/3

8:27 am-2:45 pm

1 stop6h 18m

$323

MedellínGuayaquil

MDE - GYE

MDEGYE

Medellín Jose Maria Cordova Intl

lun. 3/16

4:30 pm-11:55 pm

1 stop7h 25m

Guayaquil Jose Joaquin de Olmedo

mié. 3/18

8:32 am-2:44 pm

1 stop6h 12m

$323

MedellínGuayaquil

MDE - GYE

MDEGYE

Medellín Jose Maria Cordova Intl

mié. 3/18

10:46 am-11:41 pm

1 stop12h 55m

Guayaquil Jose Joaquin de Olmedo

lun. 6/15

8:27 am-2:45 pm

1 stop6h 18m

$333

MedellínGuayaquil

MDE - GYE

MDEGYE

Medellín Jose Maria Cordova Intl

dom. 3/22

9:50 am-2:30 pm

1 stop4h 40m

$185

MedellínGuayaquil

MDE - GYE

MDEGYE

Medellín Jose Maria Cordova Intl

mié. 4/1

3:14 pm-8:53 pm

1 stop5h 39m

$193

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 14 results
1
2
  • Most accurate provider: When it comes to deals on Medellín Jose Maria Cordova Intl Airport-Guayaquil flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Medellín Jose Maria Cordova Intl Airport-Guayaquil flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Medellín Jose Maria Cordova Intl Airport-Guayaquil flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Medellín Jose Maria Cordova Intl Airport-Guayaquil flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Medellín Jose Maria Cordova Intl Airport-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Jose Maria Cordova Intl to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Jose Maria Cordova Intl with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medellín Jose Maria Cordova Intl Airport to Guayaquil

How far ahead should I book a flight from Medellín Jose Maria Cordova Intl Airport to Guayaquil?

Use this chart to determine the optimal time to book a round-trip flight from Jose Maria Cordova Intl to Guayaquil. Price data was last updated on January 23, 2026.

Booking 37 days in advance of your planned departure date is, on average, the best time to get cheap flights from Medellín Jose Maria Cordova Intl Airport to Guayaquil. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Medellín Jose Maria Cordova Intl Airport to Guayaquil?

Currently, November is the cheapest month in which you can book a flight from Medellín Jose Maria Cordova Intl Airport to Guayaquil (average of $141). Flying from Medellín Jose Maria Cordova Intl Airport to Guayaquil in October is currently the most expensive (average of $247). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDE to GYE?

Find hourly flight availability from Jose Maria Cordova Intl to Guayaquil. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated enero 29, 2026.

When flying from Medellín Jose Maria Cordova Intl Airport to Guayaquil, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Guayaquil

Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated enero 29, 2026.
Read reviews from past customers who have flown Avianca from Medellín Jose Maria Cordova Intl Airport to Guayaquil. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Avianca
6.6
Okay
2,492 reviews

Entertainment

5.4

Crew

7.2

Comfort

6.2

Overall

6.6

Boarding

6.9

Food

5.0

Reviews

1 / 20
6.0
Good

Adrian,Sep 2025

MDE - CUN

It was a decent flight. No extras like a meal or a snack. But would do it again as the pricing was right.
Avianca
6.6
Okay
2,492 reviews
Avianca
6.6
Okay
2,492 reviews

Entertainment

5.4

Crew

7.2

Comfort

6.2

Overall

6.6

Boarding

6.9

Food

5.0

Reviews

1 / 20
6.0
Good

Adrian,Sep 2025

MDE - CUN

It was a decent flight. No extras like a meal or a snack. But would do it again as the pricing was right.

Related info for your journey

Find useful and relevant information for your journey from Jose Maria Cordova Intl to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Guayaquil from Medellín Jose Maria Cordova Intl?

    Most people fly into Guayaquil Jose Joaquin de Olmedo (GYE) if they book a flight to Guayaquil from Medellín Jose Maria Cordova Intl. On average, Jose Joaquin de Olmedo has 0 inbound flights from Medellín Jose Maria Cordova Intl per day from 1 airline. Guayaquil Jose Joaquin de Olmedo is conveniently located just 2.5 mi from Guayaquil’s city center.

  • How long is the flight from Medellín Jose Maria Cordova Intl Airport to Guayaquil?

    Airlines like Copa Airlines and Avianca fly from Medellín Jose Maria Cordova Intl Airport to Guayaquil in about 2h. The time it takes to get you to your destination can typically vary by up to 6h 33m. Medellín Jose Maria Cordova Intl Airport and Guayaquil are separated by a distance of 652 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Medellín Jose Maria Cordova Intl Airport to Guayaquil round-trip?

    Currently priced at $253, Avianca will fly you from Medellín Jose Maria Cordova Intl Airport to Guayaquil and back. In addition to Avianca, many other airlines offer competitively priced options for your trip. Avianca is priced at 12% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Jose Maria Cordova Intl to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Jose Maria Cordova Intl to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Jose Maria Cordova Intl to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jose Maria Cordova Intl to Guayaquil.

  • Can I find deals for business class flights from Jose Maria Cordova Intl to Guayaquil?

    Yes. Cheapflights offers flight deals from Jose Maria Cordova Intl to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medellín Jose Maria Cordova Intl Airport to Guayaquil?

    Currently, November is the cheapest month in which you can book a flight from Medellín Jose Maria Cordova Intl Airport to Guayaquil (average of $141). Flying from Medellín Jose Maria Cordova Intl Airport to Guayaquil in October is currently the most expensive (average of $247). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Jose Maria Cordova Intl to Guayaquil

See prices for flight routes from nearby airports that may be better suited for you.
Jose Maria Cordova Intl to Quito flights

Top airline flying from Jose Maria Cordova Intl to Guayaquil

Discover the top airline that operate flights from Jose Maria Cordova Intl to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$253Average$333FlexibilityNo cancel feeOn-time71%

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